Cend1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cend1
Entrez Gene ID	57754
Full Name	cell cycle exit and neuronal differentiation 1
Synonyms	1500001H12Rik,AI415214,BM88
General protein information	Preferred Names cell cycle exit and neuronal differentiation 1 Names cell cycle exit and neuronal differentiation protein 1 BM88 antigen
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F5

mRNA and Protein(s)

mRNA	Protein	Name
NM_021316.5	NP_067291.1	cell cycle exit and neuronal differentiation protein 1
XM_006536217.2	XP_006536280.1	cell cycle exit and neuronal differentiation protein 1 isoform X1
NM_001360485.1	NP_001347414.1	cell cycle exit and neuronal differentiation protein 1
NM_021316.4	NP_067291.1	cell cycle exit and neuronal differentiation protein 1
XM_006536217.3	XP_006536280.1	cell cycle exit and neuronal differentiation protein 1 isoform X1

Pathways from BioSystems

Homologies

	CEND1	XP_002799478.1
Mus musculus (house mouse)	Cend1	NP_067291.1
Homo sapiens (human)	CEND1	NP_057648.2
Pan troglodytes (chimpanzee)	CEND1	XP_001150340.2

Gene Ontology
Bibliography

Related articles in PubMed

CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons.
Aravantinou-Fatorou K, Ortega F, Chroni-Tzartou D, Antoniou N, Poulopoulou C, Politis PK, Berninger B, Matsas R, Thomaidou D
Stem cell reports5(3)405-18(2015 Sep)

Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation.
Weng L, Lin YF, Li AL, Wang CE, Yan S, Sun M, Gaertig MA, Mitha N, Kosaka J, Wakabayashi T, Xu X, Tang B, Li S, Li XJ
The Journal of neuroscience : the official journal of the Society for Neuroscience33(19)8172-84(2013 May)

Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.
Tsioras K, Papastefanaki F, Politis PK, Matsas R, Gaitanou M
PloS one8(11)e82172(2013)

Impaired cerebellar development and deficits in motor coordination in mice lacking the neuronal protein BM88/Cend1.
Sergaki MC, Guillemot F, Matsas R
Molecular and cellular neurosciences44(1)15-29(2010 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data suggest that common reprogramming mechanisms exist driving the conversion of lineage-distant somatic cell types to neurons and reveal a critical role for CEND1 in NEUROG2-driven astrocytic reprogramming.
Title: CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons.

This study suggested that Cend1 is involved in Ahi1-associated hypothalamic neuronal differentiation in early development, giving us fresh insight into the mechanism behind the delayed development in Joubert syndrome.
Title: Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation.

results suggest that functional interactions between BM88/Cend1, RanBPM and Dyrk1B affect the balance between cellular proliferation and differentiation in Neuro 2a cells
Title: Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.

Our results suggest that Cend1 is required for normal cerebellar development.
Title: Impaired cerebellar development and deficits in motor coordination in mice lacking the neuronal protein BM88/Cend1.

Transplantation of BM88/Cend1-overexpressing neural progenitor cells exerts beneficial effects on tissue regeneration by enhancing the number of generated neurons and restricting the formation of astroglial scar, in a mouse model of cortical brain injury.
Title: Transplantation of embryonic neural stem/precursor cells overexpressing BM88/Cend1 enhances the generation of neuronal cells in the injured mouse cortex.

The following Cend1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cend1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu12165	NM_021316.5 Latest version!	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu12165	NM_001360485.1 Latest version!	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu12165	XM_006536217.3 Latest version!	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu12165	NM_021316.4	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu12165	XM_006536217.2	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cend1 ( NM_021316.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067291.1 Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu12165
Clone ID Related Accession (Same CDS sequence)	NM_021316.5 , XM_006536217.2 , NM_001360485.1 , NM_021316.4 , XM_006536217.3
Accession Version	NM_021316.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-10
Organism	Mus musculus(house mouse)
Product	cell cycle exit and neuronal differentiation protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102547.8, AK079045.1 and AC163434.5. On Feb 6, 2018 this sequence version replaced NM_021316.4. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC023032.1, AK079045.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164136 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067291.1
CDS	345..794
Translation	MESRGKSASSPKPDTKVPQATAEAKATPAADGKAPLTKPVKKDTQAEKQEQAAAPGPAATKKTPAKADPVLLNNHSNLKPAPTVPAAPSSPDATSEPKGPGDGAEEDESNTGGRGPWPCENLTPLLVAGGVAVATIALILGVAFLARKK

Target ORF information:

RefSeq Version	NM_021316.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021316.5

ORF Insert Sequence:

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cend1 ( NM_001360485.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001347414.1 Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu12165
Clone ID Related Accession (Same CDS sequence)	NM_021316.5 , XM_006536217.2 , NM_001360485.1 , NM_021316.4 , XM_006536217.3
Accession Version	NM_001360485.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	cell cycle exit and neuronal differentiation protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC102547.8 and AC163434.5. On Feb 6, 2018 this sequence version replaced XM_006536217.3. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK005092.1, SRR1660813.388105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001347414.1
CDS	387..836
Translation	MESRGKSASSPKPDTKVPQATAEAKATPAADGKAPLTKPVKKDTQAEKQEQAAAPGPAATKKTPAKADPVLLNNHSNLKPAPTVPAAPSSPDATSEPKGPGDGAEEDESNTGGRGPWPCENLTPLLVAGGVAVATIALILGVAFLARKK

Target ORF information:

RefSeq Version	NM_001360485.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001360485.1

ORF Insert Sequence:

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cend1 ( NM_021316.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067291.1 Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), mRNA.

Price & Availability↑

CloneID	OMu12165
Clone ID Related Accession (Same CDS sequence)	NM_021316.5 , XM_006536217.2 , NM_001360485.1 , NM_021316.4 , XM_006536217.3
Accession Version	NM_021316.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Mus musculus(house mouse)
Product	cell cycle exit and neuronal differentiation protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK079045.1. On Dec 23, 2008 this sequence version replaced NM_021316.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK079045.1, SRR1660811.37605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164136 [ECO:0000348] ##Evidence-Data-END##

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067291.1
CDS	203..652
Translation	MESRGKSASSPKPDTKVPQATAEAKATPAADGKAPLTKPVKKDTQAEKQEQAAAPGPAATKKTPAKADPVLLNNHSNLKPAPTVPAAPSSPDATSEPKGPGDGAEEDESNTGGRGPWPCENLTPLLVAGGVAVATIALILGVAFLARKK

Target ORF information:

RefSeq Version	NM_021316.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021316.4

ORF Insert Sequence:

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cend1 ( XM_006536217.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536280.1 Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu12165
Clone ID Related Accession (Same CDS sequence)	NM_021316.5 , XM_006536217.2 , NM_001360485.1 , NM_021316.4 , XM_006536217.3
Accession Version	XM_006536217.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	cell cycle exit and neuronal differentiation protein 1 isoform X1
Comment

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536280.1
Translation	MESRGKSASSPKPDTKVPQATAEAKATPAADGKAPLTKPVKKDTQAEKQEQAAAPGPAATKKTPAKADPVLLNNHSNLKPAPTVPAAPSSPDATSEPKGPGDGAEEDESNTGGRGPWPCENLTPLLVAGGVAVATIALILGVAFLARKK

Target ORF information:

RefSeq Version	XM_006536217.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536217.2

ORF Insert Sequence:

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cend1 ( XM_006536217.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006536280.1 Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu12165
Clone ID Related Accession (Same CDS sequence)	NM_021316.5 , XM_006536217.2 , NM_001360485.1 , NM_021316.4 , XM_006536217.3
Accession Version	XM_006536217.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	cell cycle exit and neuronal differentiation protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006536217.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006536280.1
CDS	365..814
Translation	MESRGKSASSPKPDTKVPQATAEAKATPAADGKAPLTKPVKKDTQAEKQEQAAAPGPAATKKTPAKADPVLLNNHSNLKPAPTVPAAPSSPDATSEPKGPGDGAEEDESNTGGRGPWPCENLTPLLVAGGVAVATIALILGVAFLARKK

Target ORF information:

RefSeq Version	XM_006536217.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell cycle exit and neuronal differentiation 1 (Cend1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006536217.3

ORF Insert Sequence:

ATGGAATCCC GAGGAAAGTC AGCCAGCAGC CCCAAGCCAG ATACCAAGGT GCCTCAGGCC 
ACAGCTGAGG CCAAGGCCAC TCCAGCTGCG GATGGGAAAG CTCCCTTGAC CAAGCCTGTG 
AAGAAGGACA CCCAAGCAGA GAAGCAGGAG CAAGCAGCAG CCCCTGGGCC AGCCGCTACG 
AAGAAGACAC CAGCCAAGGC AGATCCTGTA CTTCTCAACA ACCACAGCAA CCTGAAGCCA 
GCTCCCACAG TGCCGGCAGC CCCCAGCAGT CCTGATGCAA CCTCAGAGCC CAAGGGTCCT 
GGGGATGGGG CAGAGGAGGA CGAGTCCAAC ACTGGAGGCC GAGGTCCCTG GCCTTGTGAG 
AACTTGACCC CTTTGCTGGT AGCTGGGGGT GTGGCCGTGG CCACCATAGC TCTAATTCTT 
GGTGTGGCCT TTCTAGCCCG GAAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons.
Stem cell reports5(3)405-18(2015 Sep)
Aravantinou-Fatorou K,Ortega F,Chroni-Tzartou D,Antoniou N,Poulopoulou C,Politis PK,Berninger B,Matsas R,Thomaidou D

Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience33(19)8172-84(2013 May)
Weng L,Lin YF,Li AL,Wang CE,Yan S,Sun M,Gaertig MA,Mitha N,Kosaka J,Wakabayashi T,Xu X,Tang B,Li S,Li XJ

Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.
PloS one8(11)e82172(2013)
Tsioras K,Papastefanaki F,Politis PK,Matsas R,Gaitanou M

Impaired cerebellar development and deficits in motor coordination in mice lacking the neuronal protein BM88/Cend1.
Molecular and cellular neurosciences44(1)15-29(2010 May)
Sergaki MC,Guillemot F,Matsas R

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Cend1 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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