Jmy cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Jmy
Entrez Gene ID	57748
Full Name	junction-mediating and regulatory protein
General protein information	Preferred Names junction-mediating and regulatory protein Names junction-mediating and -regulatory protein p300 transcriptional cofactor JMY
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_021310.3	NP_067285.2	junction-mediating and -regulatory protein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	JMY	XP_003639003.1
	JMY	XP_002804487.1
Danio rerio (zebrafish)	jmy	NP_998437.1
Xenopus tropicalis (tropical clawed frog)	jmy	NP_001106426.1
Homo sapiens (human)	JMY	NP_689618.4
Pan troglodytes (chimpanzee)	JMY	XP_517685.3
Bos taurus (cattle)	JMY	XP_002690504.1
Mus musculus (house mouse)	Jmy	NP_067285.2
Gallus gallus (chicken)	JMY	XP_003642959.1

Gene Ontology
Bibliography

Related articles in PubMed

Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex.
Gong W, Gohla RM, Bowlin KM, Koyano-Nakagawa N, Garry DJ, Shi X
The Journal of biological chemistry290(24)15350-61(2015 Jun)

JMY is involved in anterograde vesicle trafficking from the trans-Golgi network.
Schl?ter K, Waschb?sch D, Anft M, H?gging D, Kind S, H?nisch J, Lakisic G, Gautreau A, Barnekow A, Stradal TE
European journal of cell biology93(5-6)194-204(2014 May-Jun)

Role of nucleation-promoting factors in mouse early embryo development.
Wang QC, Liu J, Wang F, Duan X, Dai XX, Wang T, Liu HL, Cui XS, Sun SC, Kim NH
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada19(3)559-64(2013 Jun)

Nucleation promoting factors regulate the expression and localization of Arp2/3 complex during meiosis of mouse oocytes.
Liu J, Wang QC, Wang F, Duan X, Dai XX, Wang T, Liu HL, Cui XS, Kim NH, Sun SC
PloS one7(12)e52277(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

JMY drives vesicular trafficking in the trans-Golgi region and at ER-membrane contact sites, distinct from other Arp2/3 activators involved in vesicle transport processes such as the related WHAMM or WASH.
Title: JMY is involved in anterograde vesicle trafficking from the trans-Golgi network.

Results of the present study show that the nucleation-promoting factors JMY and WAVE2 are critical for cytokinesis during development of mouse embryos.
Title: Role of nucleation-promoting factors in mouse early embryo development.

The protein and messenger RNA levels of JMY were decreased in aged oocytes, but the levels were normal in caffeine-treated aged oocytes.
Title: Degradation of actin nucleators affects cortical polarity of aged mouse oocytes.

JMY is a modulator of neuritogenesis
Title: The actin nucleation factor JMY is a negative regulator of neuritogenesis.

JMY is required for spindle migration, asymmetric division and cytokinesis during mouse oocyte maturation.
Title: JMY is required for asymmetric division and cytokinesis in mouse oocytes.

The following Jmy gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Jmy cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12156	NM_021310.3 Latest version!	Mus musculus junction-mediating and regulatory protein (Jmy), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Jmy ( NM_021310.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067285.2 Mus musculus junction-mediating and regulatory protein (Jmy), mRNA.

Price & Availability↑

CloneID	OMu12156
Clone ID Related Accession (Same CDS sequence)	NM_021310.3
Accession Version	NM_021310.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2952bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	junction-mediating and -regulatory protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK141957.1, BC090835.1 and AC154231.2. On Mar 23, 2011 this sequence version replaced NM_021310.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC090835.1, AF201390.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTTCG CGCTGGAGGA GACACTCGAG TCCGACTGGG TGGCGGTGCG GCCCCACGTA 
TTCGACGAGC GCGAGAAGCA CAAGTTTGTG TTCATTGTGG CCTGGAACGA GATCGAAGGC 
AAGTTTGCTA TAACCTGTCA CAACCGGACG GCCCAGAGAC AGAGGAGCGG TTCCCGGGAA 
CAGGCGGGGA CGCCCGCGTC TGATGGGAGT CGCGGTCCGG GCAGCCCCGC GGCCAGGGGT 
CGGTCAGAGG CCGCTGCCTC TGCTACAGCA GCGCTCCGGA GTCCCGGGCC ACGGAAAAGC 
CAGGCCTGGG CCGAGGGCGG CTCTCCGCGC AGCGCGCGCA GCCTGAAGGG GGATCCTCCT 
CGGGGTCCCG CGGGCAGAGG ACCGGAGAGT CCTCTCCGTA GCCCCGCGCG GGCTAAGGCC 
AGCCCGCTCC GCAGAAGCGC CGAATCCCGA GATGCGACCG CCAGTGCCAC GCCAGCCCCG 
CCGGCGCCCC CGGTGCCCCC GGTGTCGTCG GTGCGGGTGG TGAGTGCCTC CGGGGCGGTC 
TCCGAGGAGA TCGAGGTCCT GGAAATGGTG AGGGAGGACG AGGCGCCACA GCCGCTCCCG 
GACTCGGAGC AGCCGCCGTC TGCCGCGGAG CTGGAGTCTC CGGCCGAAGA ATGCAGCTGG 
GCCGGGCTTT TCTCCTTCCA GGATCTGCGA GCCGTGCATC AGCAGCTGTG CTCGGTAAAC 
TCCCAGCTGG AGCCGTGTCT GCCGGTGTTC CCCGAAGAGC CGTCAGGCAT GTGGACGGTG 
CTGTTTGGGG GCGCCCCCGA GATGACCGAG CAGGAGATCG ACGCTCTATG TTACCAACTC 
CAGGTATACC TGGGCCACGG CCTGGACACG TGTGGCTGGA AGATCCTTTC TCAGGTTCTT 
TTCACCGAGA CGGATGATCC GGAGGAGTAT TACGAAAGCC TCAGCGAGCT GCGGCAGAAG 
GGCTATGAAG AGGTGCTTCA GCGGGCCAGG AGGCGCATCC AGGAGCTCTT GGACAAGCAC 
AAGACTATAG AAAGCATGGT AGAGCTTTTG GACTTGTATC AGATGGAGGA TGAAGCCTAC 
AGCAGCCTTG CAGAGGCCAC AACTGAACTC TACCAGTATT TACTTCAGCC ATTCCGAGAC 
ATGCGAGAAC TGGCCATGCT ACGAAGACAG CAGATCAAGA TTTCCATGGA GAATGATTAT 
TTGGGCCCTC GAAGAATTGA GAGTCTACAG AAAGAAGATG CTGACTGGCA GCGGAAAGCT 
CACATGGCTG TTTTGTCTAT TCAGGATCTC ACCGTCAAAT ATTTTGAAAT AACAGCAAAA 
GCTCAGAAAG CTGTGTATGA TCGGATGCGA GCAGATCAGA AGAAATTTGG CAAAGCATCG 
TGGGCAGCAG CTGCTGAGCG AATGGAAAAA CTCCAGTATG CAGTTTCTAA AGAGACTTTG 
CAGATGATGA GAGCTAAAGA AATTTGTCTG GAACAGAAGA AACATGCACT AAAAGAAGAG 
ATGCAAAGCT TACAGGGTGG TACAGAAGCT ATAGCTCGAT TGGATCAGCT GGAATCTGAC 
TACTATGATC TGCAACTTCA GTTGTATGAA GTACAGTTTG AAATCTTGAA GTGTGAAGAG 
TTGTTATTAA CTGCACAGCT GGAGAGCATC AAGAGACTTA TATCAGAAAA GAGAGATGAA 
GTGGTGTACT ACGACACTTA CGAAAGCATG GAGGCCATGC TGGAGAAGGA AGAGATGGCA 
GCGTCTGTGC ACGCCCAGAG GGAAGAGCTA CAGAAACTGC AGCAGAAGGC ACGCCAGCTG 
GAAGCAAGAA GGGGCCGTGT CTCAGCCAAG AAAGCCTACC TCAGAAATAA AAAAGAAATT 
TGCATTGCAA AACACCATGA GAAGTTCCAG CAGCGTTTTC AGAGTGAAGA TGAATATAGA 
GCCCATCATA CAATACAAAT AAAGAGAGAC AAATTGCATG ATGAAGAGGA AAGAAAAAGT 
GCCTGGGTTA GCCAAGAGAG ACAGAGGACA CTGGATAGAC TTCGAACATT TAAGCAGAGG 
TACCCCGGGC AAGTCATCCT TAAGTCGACC AGATTACGAG TGGCGCATTC AAGAAGAAAA 
AGCACAGCAA GCCCTGTGCC CTGTGAGGAG CAGTGTCACT CTCTGCCAAC AGTGCTGCAG 
GGGCAGGAGA AGACAGAGGT GGGAGGAGGA GGAAGCCAGC TTGGGCCTTC ACAGACAGCA 
GAACCCCAGA GCCTTGTCCA ACTTGAAGAC ACTTCATCAG AACAACTTGA ATCCACCTCA 
TTACCTCCTC GTGCTGTCGT CAGCTCTGAA CTGCCTCCTC CACAGTCAGC TCCACTGTTG 
ACTAGTATTG ACCCCAAACC GTGTTCTGTT ACTATAGATC CTCTCCCACC CCCTCTTCCT 
CCAACACCTC CCCCTCCCCC ACCCCCACCC CCACCTCCAC CCCCACCCCT GCCTGTTGCA 
AAGGACAATG GGGCCTCCAC CACTGCAGAG ACACTGGAGA AAGATGCACT TAGGACGGAG 
GGCAATGAGA GGAGCATCCC AAAGTCGGCC AGTGCCCCCG CAGCACACCT CTTTGATAGC 
AGCCAGCTGG TCAGCGCACG GAAAAAGCTC AGAAAGACTG TGGAAGGGCT GCAGAGGAGG 
AGAGTGAGTT CACCCATGGA TGAAGTGTTA GCATCCTTGA AGCGTGGTAG CTTTCATCTG 
AAAAAGGTTG AACAGCGGAC TCTGCCTCCT TTTCCTGATG AAGATGATAG TAATAATATT 
TTGGCGCAGA TAAGGAAAGG GGTAAAGTTG AAGAAGGTTC AGAAGGAAGT TTTGAGAGAA 
TCCTTCACAC TTCTGCCTGA TACCGACCCT TTGACACGGA GTATCCACGA AGCTCTAAGA 
AGAATCAAAG AAGCGTCCCC AGAGTCAGAG GATGAGGAAG AGGCTTTGCC GTGCACAGAC 
TGGGAGAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067285.2
CDS	503..3454
Translation	MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREQAGTPASDGSRGPGSPAARGRSEAAASATAALRSPGPRKSQAWAEGGSPRSARSLKGDPPRGPAGRGPESPLRSPARAKASPLRRSAESRDATASATPAPPAPPVPPVSSVRVVSASGAVSEEIEVLEMVREDEAPQPLPDSEQPPSAAELESPAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDALCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQELLDKHKTIESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQKKHALKEEMQSLQGGTEAIARLDQLESDYYDLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDTYESMEAMLEKEEMAASVHAQREELQKLQQKARQLEARRGRVSAKKAYLRNKKEICIAKHHEKFQQRFQSEDEYRAHHTIQIKRDKLHDEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRVAHSRRKSTASPVPCEEQCHSLPTVLQGQEKTEVGGGGSQLGPSQTAEPQSLVQLEDTSSEQLESTSLPPRAVVSSELPPPQSAPLLTSIDPKPCSVTIDPLPPPLPPTPPPPPPPPPPPPPPLPVAKDNGASTTAETLEKDALRTEGNERSIPKSASAPAAHLFDSSQLVSARKKLRKTVEGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKEVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDEEEALPCTDWEN

Target ORF information:

RefSeq Version	NM_021310.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus junction-mediating and regulatory protein (Jmy), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021310.3

ORF Insert Sequence:

ATGTCGTTCG CGCTGGAGGA GACACTCGAG TCCGACTGGG TGGCGGTGCG GCCCCACGTA 
TTCGACGAGC GCGAGAAGCA CAAGTTTGTG TTCATTGTGG CCTGGAACGA GATCGAAGGC 
AAGTTTGCTA TAACCTGTCA CAACCGGACG GCCCAGAGAC AGAGGAGCGG TTCCCGGGAA 
CAGGCGGGGA CGCCCGCGTC TGATGGGAGT CGCGGTCCGG GCAGCCCCGC GGCCAGGGGT 
CGGTCAGAGG CCGCTGCCTC TGCTACAGCA GCGCTCCGGA GTCCCGGGCC ACGGAAAAGC 
CAGGCCTGGG CCGAGGGCGG CTCTCCGCGC AGCGCGCGCA GCCTGAAGGG GGATCCTCCT 
CGGGGTCCCG CGGGCAGAGG ACCGGAGAGT CCTCTCCGTA GCCCCGCGCG GGCTAAGGCC 
AGCCCGCTCC GCAGAAGCGC CGAATCCCGA GATGCGACCG CCAGTGCCAC GCCAGCCCCG 
CCGGCGCCCC CGGTGCCCCC GGTGTCGTCG GTGCGGGTGG TGAGTGCCTC CGGGGCGGTC 
TCCGAGGAGA TCGAGGTCCT GGAAATGGTG AGGGAGGACG AGGCGCCACA GCCGCTCCCG 
GACTCGGAGC AGCCGCCGTC TGCCGCGGAG CTGGAGTCTC CGGCCGAAGA ATGCAGCTGG 
GCCGGGCTTT TCTCCTTCCA GGATCTGCGA GCCGTGCATC AGCAGCTGTG CTCGGTAAAC 
TCCCAGCTGG AGCCGTGTCT GCCGGTGTTC CCCGAAGAGC CGTCAGGCAT GTGGACGGTG 
CTGTTTGGGG GCGCCCCCGA GATGACCGAG CAGGAGATCG ACGCTCTATG TTACCAACTC 
CAGGTATACC TGGGCCACGG CCTGGACACG TGTGGCTGGA AGATCCTTTC TCAGGTTCTT 
TTCACCGAGA CGGATGATCC GGAGGAGTAT TACGAAAGCC TCAGCGAGCT GCGGCAGAAG 
GGCTATGAAG AGGTGCTTCA GCGGGCCAGG AGGCGCATCC AGGAGCTCTT GGACAAGCAC 
AAGACTATAG AAAGCATGGT AGAGCTTTTG GACTTGTATC AGATGGAGGA TGAAGCCTAC 
AGCAGCCTTG CAGAGGCCAC AACTGAACTC TACCAGTATT TACTTCAGCC ATTCCGAGAC 
ATGCGAGAAC TGGCCATGCT ACGAAGACAG CAGATCAAGA TTTCCATGGA GAATGATTAT 
TTGGGCCCTC GAAGAATTGA GAGTCTACAG AAAGAAGATG CTGACTGGCA GCGGAAAGCT 
CACATGGCTG TTTTGTCTAT TCAGGATCTC ACCGTCAAAT ATTTTGAAAT AACAGCAAAA 
GCTCAGAAAG CTGTGTATGA TCGGATGCGA GCAGATCAGA AGAAATTTGG CAAAGCATCG 
TGGGCAGCAG CTGCTGAGCG AATGGAAAAA CTCCAGTATG CAGTTTCTAA AGAGACTTTG 
CAGATGATGA GAGCTAAAGA AATTTGTCTG GAACAGAAGA AACATGCACT AAAAGAAGAG 
ATGCAAAGCT TACAGGGTGG TACAGAAGCT ATAGCTCGAT TGGATCAGCT GGAATCTGAC 
TACTATGATC TGCAACTTCA GTTGTATGAA GTACAGTTTG AAATCTTGAA GTGTGAAGAG 
TTGTTATTAA CTGCACAGCT GGAGAGCATC AAGAGACTTA TATCAGAAAA GAGAGATGAA 
GTGGTGTACT ACGACACTTA CGAAAGCATG GAGGCCATGC TGGAGAAGGA AGAGATGGCA 
GCGTCTGTGC ACGCCCAGAG GGAAGAGCTA CAGAAACTGC AGCAGAAGGC ACGCCAGCTG 
GAAGCAAGAA GGGGCCGTGT CTCAGCCAAG AAAGCCTACC TCAGAAATAA AAAAGAAATT 
TGCATTGCAA AACACCATGA GAAGTTCCAG CAGCGTTTTC AGAGTGAAGA TGAATATAGA 
GCCCATCATA CAATACAAAT AAAGAGAGAC AAATTGCATG ATGAAGAGGA AAGAAAAAGT 
GCCTGGGTTA GCCAAGAGAG ACAGAGGACA CTGGATAGAC TTCGAACATT TAAGCAGAGG 
TACCCCGGGC AAGTCATCCT TAAGTCGACC AGATTACGAG TGGCGCATTC AAGAAGAAAA 
AGCACAGCAA GCCCTGTGCC CTGTGAGGAG CAGTGTCACT CTCTGCCAAC AGTGCTGCAG 
GGGCAGGAGA AGACAGAGGT GGGAGGAGGA GGAAGCCAGC TTGGGCCTTC ACAGACAGCA 
GAACCCCAGA GCCTTGTCCA ACTTGAAGAC ACTTCATCAG AACAACTTGA ATCCACCTCA 
TTACCTCCTC GTGCTGTCGT CAGCTCTGAA CTGCCTCCTC CACAGTCAGC TCCACTGTTG 
ACTAGTATTG ACCCCAAACC GTGTTCTGTT ACTATAGATC CTCTCCCACC CCCTCTTCCT 
CCAACACCTC CCCCTCCCCC ACCCCCACCC CCACCTCCAC CCCCACCCCT GCCTGTTGCA 
AAGGACAATG GGGCCTCCAC CACTGCAGAG ACACTGGAGA AAGATGCACT TAGGACGGAG 
GGCAATGAGA GGAGCATCCC AAAGTCGGCC AGTGCCCCCG CAGCACACCT CTTTGATAGC 
AGCCAGCTGG TCAGCGCACG GAAAAAGCTC AGAAAGACTG TGGAAGGGCT GCAGAGGAGG 
AGAGTGAGTT CACCCATGGA TGAAGTGTTA GCATCCTTGA AGCGTGGTAG CTTTCATCTG 
AAAAAGGTTG AACAGCGGAC TCTGCCTCCT TTTCCTGATG AAGATGATAG TAATAATATT 
TTGGCGCAGA TAAGGAAAGG GGTAAAGTTG AAGAAGGTTC AGAAGGAAGT TTTGAGAGAA 
TCCTTCACAC TTCTGCCTGA TACCGACCCT TTGACACGGA GTATCCACGA AGCTCTAAGA 
AGAATCAAAG AAGCGTCCCC AGAGTCAGAG GATGAGGAAG AGGCTTTGCC GTGCACAGAC 
TGGGAGAACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex.
The Journal of biological chemistry290(24)15350-61(2015 Jun)
Gong W,Gohla RM,Bowlin KM,Koyano-Nakagawa N,Garry DJ,Shi X

JMY is involved in anterograde vesicle trafficking from the trans-Golgi network.
European journal of cell biology93(5-6)194-204(2014 May-Jun)
Schl?ter K,Waschb?sch D,Anft M,H?gging D,Kind S,H?nisch J,Lakisic G,Gautreau A,Barnekow A,Stradal TE

Role of nucleation-promoting factors in mouse early embryo development.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada19(3)559-64(2013 Jun)
Wang QC,Liu J,Wang F,Duan X,Dai XX,Wang T,Liu HL,Cui XS,Sun SC,Kim NH

Nucleation promoting factors regulate the expression and localization of Arp2/3 complex during meiosis of mouse oocytes.
PloS one7(12)e52277(2012)
Liu J,Wang QC,Wang F,Duan X,Dai XX,Wang T,Liu HL,Cui XS,Kim NH,Sun SC