Lgi1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lgi1
Entrez Gene ID	56839
Full Name	leucine-rich repeat LGI family, member 1
Synonyms	BB130740
General protein information	Preferred Names leucine-rich repeat LGI family, member 1 Names leucine-rich glioma-inactivated protein 1 leucine-rich, glioma inactivated 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_020278.2	NP_064674.1	leucine-rich glioma-inactivated protein 1 precursor
NM_020278.3	NP_064674.1	leucine-rich glioma-inactivated protein 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LGI1	NP_005088.1
Gallus gallus (chicken)	LGI1	NP_001038120.1
Danio rerio (zebrafish)	lgi1a	NP_955921.1
Xenopus tropicalis (tropical clawed frog)	lgi1	NP_001072366.1
Pan troglodytes (chimpanzee)	LGI1	NP_001065246.1
Canis lupus familiaris (dog)	LGI1	XP_534971.2
Rattus norvegicus (Norway rat)	Lgi1	NP_665712.1
Danio rerio (zebrafish)	lgi1b	NP_001122241.1
	LGI1	XP_001093284.1
Bos taurus (cattle)	LGI1	NP_001040056.2
Mus musculus (house mouse)	Lgi1	NP_064674.1

Gene Ontology
Bibliography

Related articles in PubMed

LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels.
Seagar M, Russier M, Caillard O, Maulet Y, Fronzaroli-Molinieres L, De San Feliciano M, Boumedine-Guignon N, Rodriguez L, Zbili M, Usseglio F, Formisano-Tr?ziny C, Youssouf F, Sangiardi M, Boillot M, Baulac S, Benitez MJ, Garrido JJ, Debanne D, El Far O
Proceedings of the National Academy of Sciences of the United States of America114(29)7719-7724(2017 Jul)

LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development.
Boillot M, Lee CY, Allene C, Leguern E, Baulac S, Rouach N
Scientific reports621769(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

LGI1 has a role in regulating cortical development, which is increasingly becoming recognized as one of the causes of idiopathic epilepsy.
Title: Homozygous Deletion of the LGI1 Gene in Mice Leads to Developmental Abnormalities Resulting in Cortical Dysplasia.

LGI1 and ADAM22 form an essential synaptic organizing complex that coordinates the maturation of excitatory synapses by regulating the functional incorporation of PSD-95
Title: The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function.

Review article demonstrating that LGI1 may be an essential player in the development of the brain
Title: LGI1 is involved in the development of mouse brain.

Glutamatergic neuron-targeted loss of Lgi1 causes a severe epileptic phenotype; Lgi1 displays an essential role in brain during the whole life.
Title: Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizures.

Lgi1 contains nuclear localization signal that mediates Lgi1 localization to cytoplasm and nucleus in CNS embryonic neurons.
Title: Leucine-rich glioma inactivated 1 (Lgi1), an epilepsy-related secreted protein, has a nuclear localization signal and localizes to both the cytoplasm and the nucleus of the caudal ganglionic eminence neurons.

The following Lgi1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lgi1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11952	NM_020278.3 Latest version!	Mus musculus leucine-rich repeat LGI family, member 1 (Lgi1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
View Old Accession Versions >>
OMu11952	NM_020278.2	Mus musculus leucine-rich repeat LGI family, member 1 (Lgi1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lgi1 ( NM_020278.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064674.1 Mus musculus leucine-rich repeat LGI family, member 1 (Lgi1), mRNA.

Price & Availability↑

CloneID	OMu11952
Clone ID Related Accession (Same CDS sequence)	NM_020278.2 , NM_020278.3
Accession Version	NM_020278.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Mus musculus(house mouse)
Product	leucine-rich glioma-inactivated protein 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC066090.1. On Feb 22, 2004 this sequence version replaced NM_020278.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC066090.1, SRR1660823.118202.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849390 [ECO:0000348] ##Evidence-Data-END##

ATGGAATCAG AAAGCAGCAG AAGGATGGGA AATGCCTGCA TTCCCCTGAA AAGAATTGCC 
TATTTCCTAT GCCTCTTTTC TGTGGTTTTG CTGACTGAGG GGAAGAAACC AGCGAAGCCA 
AAATGCCCTG CCGTGTGTAC TTGTAGCAAA GATAACGCTT TATGTGAGAA TGCGAGATCC 
ATTCCACGCA CCGTTCCTCC TGATGTTATC TCACTATCCT TTGTGAGATC TGGTTTTACT 
GAAATCTCAG AAGGGAGTTT CTTATTCACA CCATCGCTGC AGCTCTTGTT ATTTACGTCG 
AACTCCTTTG ATGTGATCAG TGATGATGCT TTTATTGGTC TTCCACATCT AGAATATTTA 
TTCATAGAAA ACAACAATAT CAAGTCCATT TCAAGACATA CTTTCCGGGG ACTCAAGTCT 
TTGATTCACT TGAGTCTTGC AAACAACAAT CTCCAGACAC TCCCAAAAGA CATTTTCAAA 
GGCCTGGATT CCTTAACAAA TGTGGACCTA AGAGGGAACG CATTTAATTG TGACTGTAAG 
TTGAAGTGGC TGGTGGAATG GCTCGGCCAT ACCAATGCAA CTGTGGAAGA CATCTACTGT 
GAAGGCCCAC CGGAATATAA GAAACGGAAA ATCAATAGCC TCTCCCCCAA GGATTTTGAC 
TGTATCATTA CAGAATTTGC AAAGTCCCAA GACCTACCTT ATCAGTCGCT GTCCATAGAC 
ACTTTTTCTT ATTTGAATGA TGAATATGTA GTCATTGCTC AGCCTTTTAC TGGAAAATGC 
ATTTTCCTGG AATGGGACCA CGTAGAGAAG ACCTTCCGGA ATTATGACAA CATTACAGGC 
ACGTCCACTG TGGTGTGCAA GCCCATAGTT ATTGACACTC AGCTCTATGT CATTGTGGCC 
CAGCTGTTTG GTGGCTCTCA TATCTATAAG CGAGATGGTT TTGCAAACAA ATTCATAAAA 
ATCCAAGATA TTGAAGTTCT CAAAATTCGA AAACCCAATG ACATCGAAAC ATTCAAGATT 
GAAGACAACT GGTACTTCGT TGTCGCTGAC AGTTCCAAAG CTGGGTTTAC TACCATTTAC 
AAGTGGAATG GAAACGGATT CTACTCCCAC CAATCCTTAC ATGCCTGGTA CAGGGATACT 
GATGTGGAAT ACCTTGAAAT AGCCAGACCA CCATTGGCCC TCAGAACACC TCATTTAATC 
CTGTCCAGTA GTTCTCAGCG CCCTGTTATT TACCAGTGGA GCAAAGCAAC ACAGCTATTC 
ACTAACCAAA CCGACATTCC TAACATGGAG GACGTATACG CGGTGAAGCA CTTCTCTGTG 
AAAGGTGATG TGTACATCTG CTTGACCAGA TTCATTGGCG ACTCTAAAGT CATGAAGTGG 
GGCGGCTCCT CCTTCCAGGA CATCCAGAGG ATGCCATCTC GAGGATCCAT GGTGTTCCAA 
CCTCTTCAGA TAAATAATTA CCAATATGCA ATTCTCGGAA GCGATTACTC CTTTACTCAA 
GTGTATAACT GGGATGCAGA GAAAGCCAAA TTTGTGAAGT TTCAGGAGTT AAACGTTCAG 
GCACCCAGAT CATTCACACA CGTATCCATT AATAAGCGTA ATTTTCTCTT TGCTTCCAGT 
TTTAAGGGAA ACACGCAGAT TTACAAACAT GTCATAGTTG ACTTAAGCGC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064674.1
CDS	102..1775
Translation	MESESSRRMGNACIPLKRIAYFLCLFSVVLLTEGKKPAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNAFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSPKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIDTQLYVIVAQLFGGSHIYKRDGFANKFIKIQDIEVLKIRKPNDIETFKIEDNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIARPPLALRTPHLILSSSSQRPVIYQWSKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA

Target ORF information:

RefSeq Version	NM_020278.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine-rich repeat LGI family, member 1 (Lgi1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020278.2

ORF Insert Sequence:

ATGGAATCAG AAAGCAGCAG AAGGATGGGA AATGCCTGCA TTCCCCTGAA AAGAATTGCC 
TATTTCCTAT GCCTCTTTTC TGTGGTTTTG CTGACTGAGG GGAAGAAACC AGCGAAGCCA 
AAATGCCCTG CCGTGTGTAC TTGTAGCAAA GATAACGCTT TATGTGAGAA TGCGAGATCC 
ATTCCACGCA CCGTTCCTCC TGATGTTATC TCACTATCCT TTGTGAGATC TGGTTTTACT 
GAAATCTCAG AAGGGAGTTT CTTATTCACA CCATCGCTGC AGCTCTTGTT ATTTACGTCG 
AACTCCTTTG ATGTGATCAG TGATGATGCT TTTATTGGTC TTCCACATCT AGAATATTTA 
TTCATAGAAA ACAACAATAT CAAGTCCATT TCAAGACATA CTTTCCGGGG ACTCAAGTCT 
TTGATTCACT TGAGTCTTGC AAACAACAAT CTCCAGACAC TCCCAAAAGA CATTTTCAAA 
GGCCTGGATT CCTTAACAAA TGTGGACCTA AGAGGGAACG CATTTAATTG TGACTGTAAG 
TTGAAGTGGC TGGTGGAATG GCTCGGCCAT ACCAATGCAA CTGTGGAAGA CATCTACTGT 
GAAGGCCCAC CGGAATATAA GAAACGGAAA ATCAATAGCC TCTCCCCCAA GGATTTTGAC 
TGTATCATTA CAGAATTTGC AAAGTCCCAA GACCTACCTT ATCAGTCGCT GTCCATAGAC 
ACTTTTTCTT ATTTGAATGA TGAATATGTA GTCATTGCTC AGCCTTTTAC TGGAAAATGC 
ATTTTCCTGG AATGGGACCA CGTAGAGAAG ACCTTCCGGA ATTATGACAA CATTACAGGC 
ACGTCCACTG TGGTGTGCAA GCCCATAGTT ATTGACACTC AGCTCTATGT CATTGTGGCC 
CAGCTGTTTG GTGGCTCTCA TATCTATAAG CGAGATGGTT TTGCAAACAA ATTCATAAAA 
ATCCAAGATA TTGAAGTTCT CAAAATTCGA AAACCCAATG ACATCGAAAC ATTCAAGATT 
GAAGACAACT GGTACTTCGT TGTCGCTGAC AGTTCCAAAG CTGGGTTTAC TACCATTTAC 
AAGTGGAATG GAAACGGATT CTACTCCCAC CAATCCTTAC ATGCCTGGTA CAGGGATACT 
GATGTGGAAT ACCTTGAAAT AGCCAGACCA CCATTGGCCC TCAGAACACC TCATTTAATC 
CTGTCCAGTA GTTCTCAGCG CCCTGTTATT TACCAGTGGA GCAAAGCAAC ACAGCTATTC 
ACTAACCAAA CCGACATTCC TAACATGGAG GACGTATACG CGGTGAAGCA CTTCTCTGTG 
AAAGGTGATG TGTACATCTG CTTGACCAGA TTCATTGGCG ACTCTAAAGT CATGAAGTGG 
GGCGGCTCCT CCTTCCAGGA CATCCAGAGG ATGCCATCTC GAGGATCCAT GGTGTTCCAA 
CCTCTTCAGA TAAATAATTA CCAATATGCA ATTCTCGGAA GCGATTACTC CTTTACTCAA 
GTGTATAACT GGGATGCAGA GAAAGCCAAA TTTGTGAAGT TTCAGGAGTT AAACGTTCAG 
GCACCCAGAT CATTCACACA CGTATCCATT AATAAGCGTA ATTTTCTCTT TGCTTCCAGT 
TTTAAGGGAA ACACGCAGAT TTACAAACAT GTCATAGTTG ACTTAAGCGC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lgi1 ( NM_020278.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064674.1 Mus musculus leucine-rich repeat LGI family, member 1 (Lgi1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu11952
Clone ID Related Accession (Same CDS sequence)	NM_020278.2 , NM_020278.3
Accession Version	NM_020278.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Mus musculus(house mouse)
Product	leucine-rich glioma-inactivated protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ133398.1 and BC066090.1. On Jul 24, 2018 this sequence version replaced NM_020278.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC066090.1, SRR1660811.121443.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849390 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCAG AAAGCAGCAG AAGGATGGGA AATGCCTGCA TTCCCCTGAA AAGAATTGCC 
TATTTCCTAT GCCTCTTTTC TGTGGTTTTG CTGACTGAGG GGAAGAAACC AGCGAAGCCA 
AAATGCCCTG CCGTGTGTAC TTGTAGCAAA GATAACGCTT TATGTGAGAA TGCGAGATCC 
ATTCCACGCA CCGTTCCTCC TGATGTTATC TCACTATCCT TTGTGAGATC TGGTTTTACT 
GAAATCTCAG AAGGGAGTTT CTTATTCACA CCATCGCTGC AGCTCTTGTT ATTTACGTCG 
AACTCCTTTG ATGTGATCAG TGATGATGCT TTTATTGGTC TTCCACATCT AGAATATTTA 
TTCATAGAAA ACAACAATAT CAAGTCCATT TCAAGACATA CTTTCCGGGG ACTCAAGTCT 
TTGATTCACT TGAGTCTTGC AAACAACAAT CTCCAGACAC TCCCAAAAGA CATTTTCAAA 
GGCCTGGATT CCTTAACAAA TGTGGACCTA AGAGGGAACG CATTTAATTG TGACTGTAAG 
TTGAAGTGGC TGGTGGAATG GCTCGGCCAT ACCAATGCAA CTGTGGAAGA CATCTACTGT 
GAAGGCCCAC CGGAATATAA GAAACGGAAA ATCAATAGCC TCTCCCCCAA GGATTTTGAC 
TGTATCATTA CAGAATTTGC AAAGTCCCAA GACCTACCTT ATCAGTCGCT GTCCATAGAC 
ACTTTTTCTT ATTTGAATGA TGAATATGTA GTCATTGCTC AGCCTTTTAC TGGAAAATGC 
ATTTTCCTGG AATGGGACCA CGTAGAGAAG ACCTTCCGGA ATTATGACAA CATTACAGGC 
ACGTCCACTG TGGTGTGCAA GCCCATAGTT ATTGACACTC AGCTCTATGT CATTGTGGCC 
CAGCTGTTTG GTGGCTCTCA TATCTATAAG CGAGATGGTT TTGCAAACAA ATTCATAAAA 
ATCCAAGATA TTGAAGTTCT CAAAATTCGA AAACCCAATG ACATCGAAAC ATTCAAGATT 
GAAGACAACT GGTACTTCGT TGTCGCTGAC AGTTCCAAAG CTGGGTTTAC TACCATTTAC 
AAGTGGAATG GAAACGGATT CTACTCCCAC CAATCCTTAC ATGCCTGGTA CAGGGATACT 
GATGTGGAAT ACCTTGAAAT AGCCAGACCA CCATTGGCCC TCAGAACACC TCATTTAATC 
CTGTCCAGTA GTTCTCAGCG CCCTGTTATT TACCAGTGGA GCAAAGCAAC ACAGCTATTC 
ACTAACCAAA CCGACATTCC TAACATGGAG GACGTATACG CGGTGAAGCA CTTCTCTGTG 
AAAGGTGATG TGTACATCTG CTTGACCAGA TTCATTGGCG ACTCTAAAGT CATGAAGTGG 
GGCGGCTCCT CCTTCCAGGA CATCCAGAGG ATGCCATCTC GAGGATCCAT GGTGTTCCAA 
CCTCTTCAGA TAAATAATTA CCAATATGCA ATTCTCGGAA GCGATTACTC CTTTACTCAA 
GTGTATAACT GGGATGCAGA GAAAGCCAAA TTTGTGAAGT TTCAGGAGTT AAACGTTCAG 
GCACCCAGAT CATTCACACA CGTATCCATT AATAAGCGTA ATTTTCTCTT TGCTTCCAGT 
TTTAAGGGAA ACACGCAGAT TTACAAACAT GTCATAGTTG ACTTAAGCGC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064674.1
CDS	197..1870
Translation	MESESSRRMGNACIPLKRIAYFLCLFSVVLLTEGKKPAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNAFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSPKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIDTQLYVIVAQLFGGSHIYKRDGFANKFIKIQDIEVLKIRKPNDIETFKIEDNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIARPPLALRTPHLILSSSSQRPVIYQWSKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA

Target ORF information:

RefSeq Version	NM_020278.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine-rich repeat LGI family, member 1 (Lgi1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020278.3

ORF Insert Sequence:

ATGGAATCAG AAAGCAGCAG AAGGATGGGA AATGCCTGCA TTCCCCTGAA AAGAATTGCC 
TATTTCCTAT GCCTCTTTTC TGTGGTTTTG CTGACTGAGG GGAAGAAACC AGCGAAGCCA 
AAATGCCCTG CCGTGTGTAC TTGTAGCAAA GATAACGCTT TATGTGAGAA TGCGAGATCC 
ATTCCACGCA CCGTTCCTCC TGATGTTATC TCACTATCCT TTGTGAGATC TGGTTTTACT 
GAAATCTCAG AAGGGAGTTT CTTATTCACA CCATCGCTGC AGCTCTTGTT ATTTACGTCG 
AACTCCTTTG ATGTGATCAG TGATGATGCT TTTATTGGTC TTCCACATCT AGAATATTTA 
TTCATAGAAA ACAACAATAT CAAGTCCATT TCAAGACATA CTTTCCGGGG ACTCAAGTCT 
TTGATTCACT TGAGTCTTGC AAACAACAAT CTCCAGACAC TCCCAAAAGA CATTTTCAAA 
GGCCTGGATT CCTTAACAAA TGTGGACCTA AGAGGGAACG CATTTAATTG TGACTGTAAG 
TTGAAGTGGC TGGTGGAATG GCTCGGCCAT ACCAATGCAA CTGTGGAAGA CATCTACTGT 
GAAGGCCCAC CGGAATATAA GAAACGGAAA ATCAATAGCC TCTCCCCCAA GGATTTTGAC 
TGTATCATTA CAGAATTTGC AAAGTCCCAA GACCTACCTT ATCAGTCGCT GTCCATAGAC 
ACTTTTTCTT ATTTGAATGA TGAATATGTA GTCATTGCTC AGCCTTTTAC TGGAAAATGC 
ATTTTCCTGG AATGGGACCA CGTAGAGAAG ACCTTCCGGA ATTATGACAA CATTACAGGC 
ACGTCCACTG TGGTGTGCAA GCCCATAGTT ATTGACACTC AGCTCTATGT CATTGTGGCC 
CAGCTGTTTG GTGGCTCTCA TATCTATAAG CGAGATGGTT TTGCAAACAA ATTCATAAAA 
ATCCAAGATA TTGAAGTTCT CAAAATTCGA AAACCCAATG ACATCGAAAC ATTCAAGATT 
GAAGACAACT GGTACTTCGT TGTCGCTGAC AGTTCCAAAG CTGGGTTTAC TACCATTTAC 
AAGTGGAATG GAAACGGATT CTACTCCCAC CAATCCTTAC ATGCCTGGTA CAGGGATACT 
GATGTGGAAT ACCTTGAAAT AGCCAGACCA CCATTGGCCC TCAGAACACC TCATTTAATC 
CTGTCCAGTA GTTCTCAGCG CCCTGTTATT TACCAGTGGA GCAAAGCAAC ACAGCTATTC 
ACTAACCAAA CCGACATTCC TAACATGGAG GACGTATACG CGGTGAAGCA CTTCTCTGTG 
AAAGGTGATG TGTACATCTG CTTGACCAGA TTCATTGGCG ACTCTAAAGT CATGAAGTGG 
GGCGGCTCCT CCTTCCAGGA CATCCAGAGG ATGCCATCTC GAGGATCCAT GGTGTTCCAA 
CCTCTTCAGA TAAATAATTA CCAATATGCA ATTCTCGGAA GCGATTACTC CTTTACTCAA 
GTGTATAACT GGGATGCAGA GAAAGCCAAA TTTGTGAAGT TTCAGGAGTT AAACGTTCAG 
GCACCCAGAT CATTCACACA CGTATCCATT AATAAGCGTA ATTTTCTCTT TGCTTCCAGT 
TTTAAGGGAA ACACGCAGAT TTACAAACAT GTCATAGTTG ACTTAAGCGC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels.
Proceedings of the National Academy of Sciences of the United States of America114(29)7719-7724(2017 Jul)
Seagar M,Russier M,Caillard O,Maulet Y,Fronzaroli-Molinieres L,De San Feliciano M,Boumedine-Guignon N,Rodriguez L,Zbili M,Usseglio F,Formisano-Tr?ziny C,Youssouf F,Sangiardi M,Boillot M,Baulac S,Benitez MJ,Garrido JJ,Debanne D,El Far O

LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development.
Scientific reports621769(2016 Feb)
Boillot M,Lee CY,Allene C,Leguern E,Baulac S,Rouach N

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Lgi1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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