Krt71 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Krt71
Entrez Gene ID	56735
Full Name	keratin 71
Synonyms	AA589543,Ca,Cal4,Cu,Krt2-6g,mK6irs,mK6irs1
General protein information	Preferred Names keratin 71 Names keratin, type II cytoskeletal 71 CK-6G CK-71 K6G K71 caracul cytokeratin-6G cytokeratin-71 keratin complex 2, basic, gene 6g keratin complex 2, gene 6g keratin-6G mK6irs1/Krt2-6g type II inner root sheath-specific keratin-K6irs1 type-II keratin Kb34
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 F2\|15 57.0 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_019956.1	NP_064340.1	keratin, type II cytoskeletal 71

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KRT71	NP_001183958.1
Pan troglodytes (chimpanzee)	KRT71	XP_003313729.1
Gallus gallus (chicken)	KRT75L2	XP_428850.2
Homo sapiens (human)	KRT71	NP_258259.1
	LOC698941	XP_001097289.1
Bos taurus (cattle)	KRT71	NP_001069438.1
Mus musculus (house mouse)	Krt71	NP_064340.1
Rattus norvegicus (Norway rat)	Krt71	NP_001263369.1
Gallus gallus (chicken)	LOC768881	XP_001232027.2

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Fairfield H, Srivastava A, Ananda G, Liu R, Kircher M, Lakshminarayana A, Harris BS, Karst SY, Dionne LA, Kane CC, Curtain M, Berry ML, Ward-Bailey PF, Greenstein I, Byers C, Czechanski A, Sharp J, Palmer K, Gudis P, Martin W, Tadenev A, Bogdanik L, Pratt CH, Chang B, Schroeder DG, Cox GA, Cliften P, Milbrandt J, Murray S, Burgess R, Bergstrom DE, Donahue LR, Hamamy H, Masri A, Santoni FA, Makrythanasis P, Antonarakis SE, Shendure J, Reinholdt LG
Genome research25(7)948-57(2015 Jul)

iRhom2 mutation leads to aberrant hair follicle differentiation in mice.
Leilei Y, Bing L, Yang L, Shaoxia W, Yuan X, Dongping W, Huahu Y, Shichen S, Guangzhou Z, Ruiyun P, Lin Z, Wenlong L
PloS one9(12)e115114(2014)

Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis.
Jin C, Chen J, Meng Q, Carreira V, Tam NN, Geh E, Karyala S, Ho SM, Zhou X, Medvedovic M, Xia Y
Developmental biology374(1)96-107(2013 Feb)

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Sotiropoulou PA, Karambelas AE, Debaugnies M, Candi A, Bouwman P, Moers V, Revenco T, Rocha AS, Sekiguchi K, Jonkers J, Blanpain C
Genes & development27(1)39-51(2013 Jan)

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.
Dai D, Li L, Huebner A, Zeng H, Guevara E, Claypool DJ, Liu A, Chen J
Cell death and differentiation20(1)130-8(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Missense point mutations in Krt2-6g is associated with hair abnormalities
Title: Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71rco12 and Krt71rco13.

The following Krt71 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Krt71 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11865	NM_019956.1 Latest version!	Mus musculus keratin 71 (Krt71), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Krt71 ( NM_019956.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064340.1 Mus musculus keratin 71 (Krt71), mRNA.

Price & Availability↑

CloneID	OMu11865
Clone ID Related Accession (Same CDS sequence)	NM_019956.1
Accession Version	NM_019956.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	keratin, type II cytoskeletal 71
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB033744.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB033744.1, AB100413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGAGCCGCC AATTCACCTG CAAGTCTGGA GCCAGCAACA GGGGCTTCAG TGGTTGCTCC 
GCAGTGCTCT CTGGGGGAAG CTCATCCTCC TACCGGGCAG GAGGCAAAGG GCTCAGCGGG 
GGCTTTGGCA GTCGGAGTCT CTACAGCCTG GGAGGTGGCA GGAGCATCAC TCTTAACATG 
GCTAGTGGCA GCGGGAAGAA CGGAGGTTTT GGATTTGGCC GGAACCGAGC CAGTGGCTTT 
GCCGGAAGTA TCTTTGGCAG TGTGGCCCTG GGGCCCGTGT GCCCTGCTGT GTGCCCGCCT 
GGCGGTATCC ATCAGGTCAC AGTCAATGAA AGCCTTCTGG CCCCACTCAA TGTGGAGCTG 
GACCCTGAGA TCCAGAAGGT GCGCGCACAG GAGCGGGAGC AGATCAAGGC TCTGAACAAC 
AAGTTTGCCT CCTTCATTGA CAAGGTGCGC TTCTTGGAGC AGCAGAACCA GGTGCTGCAG 
ACCAAGTGGG AGCTGCTGCA GCAGCTGGAC CTGAACAACT GCAAGAACAA CCTGGAACCC 
ATCCTTGAGG GCCACATCAG CAACATGCGG AAGCAGCTGG AGACGCTGTC TGGGGACAGA 
GTGAGGCTGG ACTCTGAGCT GAGGAATGTG CGTGACGTGG TGGAGGACTA CAAGAAGAAG 
TATGAGGAGG AGATCAACCG GCGGACAGCT GCAGAGAATG AGTTTGTGCT GCTGAAGAAG 
GACGTGGATG CGGCTTATGC CAACAAGGTG GAACTGCAGG CCAAGGTGGA CACCATGGAC 
CAGGACATCA AATTCTTCAA GTGTCTGTTC GAAGCCGAGA TGGCTCAGAT CCAGTCCCAC 
ATCAGCGACA TGTCCGTCAT CCTGTCCATG GACAACAACA GGAACCTGGA CCTGGACAGC 
ATCATCGATG AGGTTCGCGC TCAGTATGAG GAGATTGCCC TGAAGAGCAA GGCTGAAGCT 
GAGGCCCTGT ACCAGACCAA GTTCCAGGAG CTGCAGCTGG CAGCTGGTCG CCATGGAGAT 
GACCTCAAAA ACACCAAAAA TGAAATCACT GAGCTGACCC GGTTCATCCA GAGACTCCGC 
TCAGAGATTG AGAACGCAAA GAAGCAGGCT TCTAACCTAG AGACAGCCAT CGCTGATGCC 
GAGCAGCGAG GTGACAGTGC CCTCAAGGAT GCCCGGGCCA AGCTGGATGA GCTGGAGGGT 
GCCCTGCACC AGGCCAAGGA GGAGCTGGCC AGGATGCTGC GTGAATATCA GGAGCTCATG 
AGCCTAAAGT TGGCCCTGGA CATGGAGATC GCCACCTACC GCAAACTTCT GGAGAGCGAG 
GAGTGCAGGA TGTCCGGAGA ATACTCTTCC CCCGTCAGCA TCTCCATTAT CAGCAGCACC 
AGTGGCAGTG GAGGCTATGG CTTCCGGCCC AGCACAGTCA GCGGTGGCTA CGTGGCCAAT 
AGCACTAGCT GCATCTCTGG AGTGTGCAGT GTCCGTGGTG GGGAGAACAG GAGCAGAGGT 
AGTGCCAGCG ACTACAAGGA TACCCTAACA AAGGGCTCCA GTCTGAGCAC CCCCTCCAAG 
AAAGGTGGCC GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064340.1
CDS	52..1626
Translation	MSRQFTCKSGASNRGFSGCSAVLSGGSSSSYRAGGKGLSGGFGSRSLYSLGGGRSITLNMASGSGKNGGFGFGRNRASGFAGSIFGSVALGPVCPAVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLQTKWELLQQLDLNNCKNNLEPILEGHISNMRKQLETLSGDRVRLDSELRNVRDVVEDYKKKYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDTMDQDIKFFKCLFEAEMAQIQSHISDMSVILSMDNNRNLDLDSIIDEVRAQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEITELTRFIQRLRSEIENAKKQASNLETAIADAEQRGDSALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEYSSPVSISIISSTSGSGGYGFRPSTVSGGYVANSTSCISGVCSVRGGENRSRGSASDYKDTLTKGSSLSTPSKKGGR

Target ORF information:

RefSeq Version	NM_019956.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus keratin 71 (Krt71), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019956.1

ORF Insert Sequence:

ATGAGCCGCC AATTCACCTG CAAGTCTGGA GCCAGCAACA GGGGCTTCAG TGGTTGCTCC 
GCAGTGCTCT CTGGGGGAAG CTCATCCTCC TACCGGGCAG GAGGCAAAGG GCTCAGCGGG 
GGCTTTGGCA GTCGGAGTCT CTACAGCCTG GGAGGTGGCA GGAGCATCAC TCTTAACATG 
GCTAGTGGCA GCGGGAAGAA CGGAGGTTTT GGATTTGGCC GGAACCGAGC CAGTGGCTTT 
GCCGGAAGTA TCTTTGGCAG TGTGGCCCTG GGGCCCGTGT GCCCTGCTGT GTGCCCGCCT 
GGCGGTATCC ATCAGGTCAC AGTCAATGAA AGCCTTCTGG CCCCACTCAA TGTGGAGCTG 
GACCCTGAGA TCCAGAAGGT GCGCGCACAG GAGCGGGAGC AGATCAAGGC TCTGAACAAC 
AAGTTTGCCT CCTTCATTGA CAAGGTGCGC TTCTTGGAGC AGCAGAACCA GGTGCTGCAG 
ACCAAGTGGG AGCTGCTGCA GCAGCTGGAC CTGAACAACT GCAAGAACAA CCTGGAACCC 
ATCCTTGAGG GCCACATCAG CAACATGCGG AAGCAGCTGG AGACGCTGTC TGGGGACAGA 
GTGAGGCTGG ACTCTGAGCT GAGGAATGTG CGTGACGTGG TGGAGGACTA CAAGAAGAAG 
TATGAGGAGG AGATCAACCG GCGGACAGCT GCAGAGAATG AGTTTGTGCT GCTGAAGAAG 
GACGTGGATG CGGCTTATGC CAACAAGGTG GAACTGCAGG CCAAGGTGGA CACCATGGAC 
CAGGACATCA AATTCTTCAA GTGTCTGTTC GAAGCCGAGA TGGCTCAGAT CCAGTCCCAC 
ATCAGCGACA TGTCCGTCAT CCTGTCCATG GACAACAACA GGAACCTGGA CCTGGACAGC 
ATCATCGATG AGGTTCGCGC TCAGTATGAG GAGATTGCCC TGAAGAGCAA GGCTGAAGCT 
GAGGCCCTGT ACCAGACCAA GTTCCAGGAG CTGCAGCTGG CAGCTGGTCG CCATGGAGAT 
GACCTCAAAA ACACCAAAAA TGAAATCACT GAGCTGACCC GGTTCATCCA GAGACTCCGC 
TCAGAGATTG AGAACGCAAA GAAGCAGGCT TCTAACCTAG AGACAGCCAT CGCTGATGCC 
GAGCAGCGAG GTGACAGTGC CCTCAAGGAT GCCCGGGCCA AGCTGGATGA GCTGGAGGGT 
GCCCTGCACC AGGCCAAGGA GGAGCTGGCC AGGATGCTGC GTGAATATCA GGAGCTCATG 
AGCCTAAAGT TGGCCCTGGA CATGGAGATC GCCACCTACC GCAAACTTCT GGAGAGCGAG 
GAGTGCAGGA TGTCCGGAGA ATACTCTTCC CCCGTCAGCA TCTCCATTAT CAGCAGCACC 
AGTGGCAGTG GAGGCTATGG CTTCCGGCCC AGCACAGTCA GCGGTGGCTA CGTGGCCAAT 
AGCACTAGCT GCATCTCTGG AGTGTGCAGT GTCCGTGGTG GGGAGAACAG GAGCAGAGGT 
AGTGCCAGCG ACTACAAGGA TACCCTAACA AAGGGCTCCA GTCTGAGCAC CCCCTCCAAG 
AAAGGTGGCC GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Genome research25(7)948-57(2015 Jul)
Fairfield H,Srivastava A,Ananda G,Liu R,Kircher M,Lakshminarayana A,Harris BS,Karst SY,Dionne LA,Kane CC,Curtain M,Berry ML,Ward-Bailey PF,Greenstein I,Byers C,Czechanski A,Sharp J,Palmer K,Gudis P,Martin W,Tadenev A,Bogdanik L,Pratt CH,Chang B,Schroeder DG,Cox GA,Cliften P,Milbrandt J,Murray S,Burgess R,Bergstrom DE,Donahue LR,Hamamy H,Masri A,Santoni FA,Makrythanasis P,Antonarakis SE,Shendure J,Reinholdt LG

iRhom2 mutation leads to aberrant hair follicle differentiation in mice.
PloS one9(12)e115114(2014)
Leilei Y,Bing L,Yang L,Shaoxia W,Yuan X,Dongping W,Huahu Y,Shichen S,Guangzhou Z,Ruiyun P,Lin Z,Wenlong L

Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis.
Developmental biology374(1)96-107(2013 Feb)
Jin C,Chen J,Meng Q,Carreira V,Tam NN,Geh E,Karyala S,Ho SM,Zhou X,Medvedovic M,Xia Y

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Genes & development27(1)39-51(2013 Jan)
Sotiropoulou PA,Karambelas AE,Debaugnies M,Candi A,Bouwman P,Moers V,Revenco T,Rocha AS,Sekiguchi K,Jonkers J,Blanpain C

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.
Cell death and differentiation20(1)130-8(2013 Jan)
Dai D,Li L,Huebner A,Zeng H,Guevara E,Claypool DJ,Liu A,Chen J

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Krt71 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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