Ankrd2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ankrd2
Entrez Gene ID	56642
Full Name	ankyrin repeat domain 2 (stretch responsive muscle)
Synonyms	Arpp,mArpp
General protein information	Preferred Names ankyrin repeat domain 2 (stretch responsive muscle) Names ankyrin repeat domain-containing protein 2 skeletal muscle ankyrin repeat protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA	Protein	Name
XM_017318264.1	XP_017173753.1	ankyrin repeat domain-containing protein 2 isoform X1
NM_020033.2	NP_064417.2	ankyrin repeat domain-containing protein 2
XM_017318264.2	XP_017173753.1	ankyrin repeat domain-containing protein 2 isoform X1
NM_020033.1	NP_064417.1	ankyrin repeat domain-containing protein 2
XM_006527234.3	XP_006527297.1	ankyrin repeat domain-containing protein 2 isoform X2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ANKRD2	XP_003587918.2
Rattus norvegicus (Norway rat)	Ankrd2	NP_001101059.1
Homo sapiens (human)	ANKRD2	NP_065082.2
Mus musculus (house mouse)	Ankrd2	NP_064417.1
	ANKRD2	XP_001095517.2
Pan troglodytes (chimpanzee)	ANKRD2	XP_507964.3
Canis lupus familiaris (dog)	ANKRD2	XP_850948.2
Gallus gallus (chicken)	ANKRD2	XP_004942257.1
Danio rerio (zebrafish)	LOC101886079	XP_005157118.1
Xenopus tropicalis (tropical clawed frog)	ankrd2	NP_001090801.1

Gene Ontology
Bibliography

Related articles in PubMed

ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase).
Andrade EC, Musante V, Horiuchi A, Matsuzaki H, Brody AH, Wu T, Greengard P, Taylor JR, Nairn AC
The Journal of neuroscience : the official journal of the Society for Neuroscience37(10)2709-2722(2017 Mar)

MLP and CARP are linked to chronic PKC? signalling in dilated cardiomyopathy.
Lange S, Gehmlich K, Lun AS, Blondelle J, Hooper C, Dalton ND, Alvarez EA, Zhang X, Bang ML, Abassi YA, Dos Remedios CG, Peterson KL, Chen J, Ehler E
Nature communications712120(2016 Jun)

Ankrd2 is a modulator of NF-?B-mediated inflammatory responses during muscle differentiation.
Bean C, Verma NK, Yamamoto DL, Chemello F, Cenni V, Filomena MC, Chen J, Bang ML, Lanfranchi G
Cell death & disease5e1002(2014 Jan)

The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overload.
Bang ML, Gu Y, Dalton ND, Peterson KL, Chien KR, Chen J
PloS one9(4)e93638(2014)

Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction.
Mohamed JS, Lopez MA, Cox GA, Boriek AM
The Journal of biological chemistry288(34)24560-8(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We describe a novel mechanism of signal transduction enriched in medium spiny neurons of striatum that likely mediates effects of the neurotransmitter dopamine acting on these cells. We find that the protein ARPP-16, which is highly expressed in striatal medium spiny neurons, acts as a selective inhibitor of certain forms of the serine/threonine protein phosphatase, PP2A, when phosphorylated by the kinase, MAST3.
Title: ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase).

Ankrd2 as a potent repressor of inflammatory responses through direct interaction with the NF-kappaB repressor subunit p50.
Title: Ankrd2 is a modulator of NF-?B-mediated inflammatory responses during muscle differentiation.

CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to mechanical pressure overload.
Title: The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overload.

a novel pathway in which SREBP-1/ANKRD2/ID3 activation inhibits myoblast differentiation, and we propose that this pathway acts as a critical determinant of the skeletal muscle developmental program.
Title: Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction.

The Ankrd2 accumulated in the nuclei of myofibers located adjacent to severely damaged myofibers after muscle injury. Ankrd2 may translocate from the I-band to the nucleus in response to muscle damage and in the regulation of gene expression.
Title: Arpp/Ankrd2, a member of the muscle ankyrin repeat proteins (MARPs), translocates from the I-band to the nucleus after muscle injury.

The following Ankrd2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ankrd2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11798	NM_020033.1 Latest version!	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu55660	XM_006527234.3 Latest version!	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu84240	NM_020033.2 Latest version!	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu80007	XM_017318264.2 Latest version!	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu80007	XM_017318264.1	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ankrd2 ( NM_020033.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064417.1 Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA.

Price & Availability↑

CloneID	OMu11798
Clone ID Related Accession (Same CDS sequence)	NM_020033.1
Accession Version	NM_020033.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Mus musculus(house mouse)
Product	ankyrin repeat domain-containing protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ245514.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ011118.1, AJ245514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849385 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGGC CCGAGGCGGT GCAGAGAGCC ACAGAGCTCA TCGAGCAGCG GCTTGCCCAG 
GAGGAAGAGA CTGAGAAACT TCGAAGATCC GCTCCTGGGA AGCTGTCCAT GGACATGCTA 
GTGCTAGAGG AAGAGAAGCG CCTCGGGGTT CAGAGTCCTG CTTTACAAAA GGTTAAGGGC 
CAAGAGCGCG TGCGCAAGAC ATCCCTGGAC CTGCGACGTG AGATCATTGA TGTGGGTGGG 
ATCCAGAACC TCATTGAACT GAGGAAAAAA CGCAAGCAGA AAAAGCGAGA TGCCCTGGCT 
GCAGCCCAGG AGCCTCCTCC AGAGCCAGAG GAGATCACCG GCCCTGTGAA TGAGGAGACA 
TTCCTGAAAG CTGCAGTGGA GGGGAAAATG AAAGTCATTG ACAAGTACCT GGCGGACGGA 
GGTTCAGCGG ACACCTGTGA TGAGTTCCGT CGGACAGCAC TGCATCGGGC CTCCCTGGAG 
GGACACATGG AGATACTGGA GAAACTTCTG GAGAATGGGG CCACCGTGGA CTTCCAGGAT 
CGGCTGGACT GCACAGCCAT GCACTGGGCC TGCCGTGGGG GCCACCTGGA GGTGGTGAGA 
CTCCTGCAAA GCCGGGGGGC CGACACCAAC GTGAGAGACA AGCTACTGAG CACTCCCCTG 
CATGTGGCCG TCCGTACTGG ACACGTGGAG ATTGTGGAAC ATTTTCTTTC CCTGGGCTTG 
GATATCAATG CCAAAGACAG AGAAGGGGAC AGTGCCCTAC ATGATGCCGT GAGACTCAAC 
CGCTACAAAA TCATCAAACT GCTGCTCTTG CATGGGGCGG ACATGATGGC TAAGAACCTG 
GCGGGAAAGA CCCCCACGGA CCTGGTCCAG CTCTGGCAAG CAGACACCCG GCATGCCCTG 
GAGCATCCCG AGCCAGAATC AGAGCAGAAC GGACTGGAGA GGCCTGGGAG TGGCCGTGAG 
ACACCTCAGC CTATACCAGC CCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064417.1
CDS	11..997
Translation	MEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRETPQPIPAQ

Target ORF information:

RefSeq Version	NM_020033.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020033.1

ORF Insert Sequence:

ATGGAGGGGC CCGAGGCGGT GCAGAGAGCC ACAGAGCTCA TCGAGCAGCG GCTTGCCCAG 
GAGGAAGAGA CTGAGAAACT TCGAAGATCC GCTCCTGGGA AGCTGTCCAT GGACATGCTA 
GTGCTAGAGG AAGAGAAGCG CCTCGGGGTT CAGAGTCCTG CTTTACAAAA GGTTAAGGGC 
CAAGAGCGCG TGCGCAAGAC ATCCCTGGAC CTGCGACGTG AGATCATTGA TGTGGGTGGG 
ATCCAGAACC TCATTGAACT GAGGAAAAAA CGCAAGCAGA AAAAGCGAGA TGCCCTGGCT 
GCAGCCCAGG AGCCTCCTCC AGAGCCAGAG GAGATCACCG GCCCTGTGAA TGAGGAGACA 
TTCCTGAAAG CTGCAGTGGA GGGGAAAATG AAAGTCATTG ACAAGTACCT GGCGGACGGA 
GGTTCAGCGG ACACCTGTGA TGAGTTCCGT CGGACAGCAC TGCATCGGGC CTCCCTGGAG 
GGACACATGG AGATACTGGA GAAACTTCTG GAGAATGGGG CCACCGTGGA CTTCCAGGAT 
CGGCTGGACT GCACAGCCAT GCACTGGGCC TGCCGTGGGG GCCACCTGGA GGTGGTGAGA 
CTCCTGCAAA GCCGGGGGGC CGACACCAAC GTGAGAGACA AGCTACTGAG CACTCCCCTG 
CATGTGGCCG TCCGTACTGG ACACGTGGAG ATTGTGGAAC ATTTTCTTTC CCTGGGCTTG 
GATATCAATG CCAAAGACAG AGAAGGGGAC AGTGCCCTAC ATGATGCCGT GAGACTCAAC 
CGCTACAAAA TCATCAAACT GCTGCTCTTG CATGGGGCGG ACATGATGGC TAAGAACCTG 
GCGGGAAAGA CCCCCACGGA CCTGGTCCAG CTCTGGCAAG CAGACACCCG GCATGCCCTG 
GAGCATCCCG AGCCAGAATC AGAGCAGAAC GGACTGGAGA GGCCTGGGAG TGGCCGTGAG 
ACACCTCAGC CTATACCAGC CCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ankrd2 ( XM_006527234.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006527297.1 Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu55660
Clone ID Related Accession (Same CDS sequence)	XM_006527234.3
Accession Version	XM_006527234.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ankyrin repeat domain-containing protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006527234.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGCTACTG 
AGCACTCCCC TGCATGTGGC CGTCCGTACT GGACACGTGG AGATTGTGGA ACATTTTCTT 
TCCCTGGGCT TGGATATCAA TGCCAAAGAC AGAGAAGGGG ACAGTGCCCT ACATGATGCC 
GTGAGACTCA ACCGCTACAA AATCATCAAA CTGCTGCTCT TGCATGGGGC GGACATGATG 
GCTAAGAACC TGGCGGGAAA GACCCCCACG GACCTGGTCC AGCTCTGGCA AGCAGACACC 
CGGCATGCCC TGGAGCATCC CGAGCCAGAA TCAGAGCAGA ACGGACTGGA GAGGCCTGGG 
AGTGGCCGTG AGACACCTCA GCCTATACCA GCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006527297.1
CDS	235..1113
Translation	MDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRETPQPIPAQ

Target ORF information:

RefSeq Version	XM_006527234.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006527234.3

ORF Insert Sequence:

ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGCTACTG 
AGCACTCCCC TGCATGTGGC CGTCCGTACT GGACACGTGG AGATTGTGGA ACATTTTCTT 
TCCCTGGGCT TGGATATCAA TGCCAAAGAC AGAGAAGGGG ACAGTGCCCT ACATGATGCC 
GTGAGACTCA ACCGCTACAA AATCATCAAA CTGCTGCTCT TGCATGGGGC GGACATGATG 
GCTAAGAACC TGGCGGGAAA GACCCCCACG GACCTGGTCC AGCTCTGGCA AGCAGACACC 
CGGCATGCCC TGGAGCATCC CGAGCCAGAA TCAGAGCAGA ACGGACTGGA GAGGCCTGGG 
AGTGGCCGTG AGACACCTCA GCCTATACCA GCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ankrd2 ( NM_020033.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_064417.2 Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA.

Price & Availability↑

CloneID	OMu84240
Clone ID Related Accession (Same CDS sequence)	NM_020033.2
Accession Version	NM_020033.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	ankyrin repeat domain-containing protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133503.4. On Jul 24, 2018 this sequence version replaced NM_020033.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB076256.1, AJ245514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849385 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGTA CCATGGAGGG GCCCGAGGCG GTGCAGAGAG CCACAGAGCT CATCGAGCAG 
CGGCTTGCCC AGGAGGAAGA GACTGAGAAA CTTCGAAGAT CCGCTCCTGG GAAGCTGTCC 
ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGCTACTG 
AGCACTCCCC TGCATGTGGC CGTCCGTACT GGACACGTGG AGATTGTGGA ACATTTTCTT 
TCCCTGGGCT TGGATATCAA TGCCAAAGAC AGAGAAGGGG ACAGTGCCCT ACATGATGCC 
GTGAGACTCA ACCGCTACAA AATCATCAAA CTGCTGCTCT TGCATGGGGC GGACATGATG 
GCTAAGAACC TGGCGGGAAA GACCCCCACG GACCTGGTCC AGCTCTGGCA AGCAGACACC 
CGGCATGCCC TGGAGCATCC CGAGCCAGAA TCAGAGCAGA ACGGACTGGA GAGGCCTGGG 
AGTGGCCGTG AGACACCTCA GCCTATACCA GCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064417.2
CDS	10..1008
Translation	MEGTMEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRETPQPIPAQ

Target ORF information:

RefSeq Version	NM_020033.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020033.2

ORF Insert Sequence:

ATGGAGGGTA CCATGGAGGG GCCCGAGGCG GTGCAGAGAG CCACAGAGCT CATCGAGCAG 
CGGCTTGCCC AGGAGGAAGA GACTGAGAAA CTTCGAAGAT CCGCTCCTGG GAAGCTGTCC 
ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGCTACTG 
AGCACTCCCC TGCATGTGGC CGTCCGTACT GGACACGTGG AGATTGTGGA ACATTTTCTT 
TCCCTGGGCT TGGATATCAA TGCCAAAGAC AGAGAAGGGG ACAGTGCCCT ACATGATGCC 
GTGAGACTCA ACCGCTACAA AATCATCAAA CTGCTGCTCT TGCATGGGGC GGACATGATG 
GCTAAGAACC TGGCGGGAAA GACCCCCACG GACCTGGTCC AGCTCTGGCA AGCAGACACC 
CGGCATGCCC TGGAGCATCC CGAGCCAGAA TCAGAGCAGA ACGGACTGGA GAGGCCTGGG 
AGTGGCCGTG AGACACCTCA GCCTATACCA GCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ankrd2 ( XM_017318264.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173753.1 Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu80007
Clone ID Related Accession (Same CDS sequence)	XM_017318264.1 , XM_017318264.2
Accession Version	XM_017318264.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ankyrin repeat domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGTA CCATGGAGGG GCCCGAGGCG GTGCAGAGAG CCACAGAGCT CATCGAGCAG 
CGGCTTGCCC AGGAGGAAGA GACTGAGAAA CTTCGAAGAT CCGCTCCTGG GAAGCTGTCC 
ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGGAAGGG 
GACAGTGCCC TACATGATGC CGTGAGACTC AACCGCTACA AAATCATCAA ACTGCTGCTC 
TTGCATGGGG CGGACATGAT GGCTAAGAAC CTGGCGGGAA AGACCCCCAC GGACCTGGTC 
CAGCTCTGGC AAGCAGACAC CCGGCATGCC CTGGAGCATC CCGAGCCAGA ATCAGAGCAG 
AACGGACTGG AGAGGCCTGG GAGTGGCCGT GAGACACCTC AGCCTATACC AGCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173753.1
CDS	119..1018
Translation	MEGTMEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKEGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRETPQPIPAQ

Target ORF information:

RefSeq Version	XM_017318264.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318264.1

ORF Insert Sequence:

ATGGAGGGTA CCATGGAGGG GCCCGAGGCG GTGCAGAGAG CCACAGAGCT CATCGAGCAG 
CGGCTTGCCC AGGAGGAAGA GACTGAGAAA CTTCGAAGAT CCGCTCCTGG GAAGCTGTCC 
ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGGAAGGG 
GACAGTGCCC TACATGATGC CGTGAGACTC AACCGCTACA AAATCATCAA ACTGCTGCTC 
TTGCATGGGG CGGACATGAT GGCTAAGAAC CTGGCGGGAA AGACCCCCAC GGACCTGGTC 
CAGCTCTGGC AAGCAGACAC CCGGCATGCC CTGGAGCATC CCGAGCCAGA ATCAGAGCAG 
AACGGACTGG AGAGGCCTGG GAGTGGCCGT GAGACACCTC AGCCTATACC AGCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ankrd2 ( XM_017318264.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173753.1 Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X1, mRNA.

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CloneID	OMu80007
Clone ID Related Accession (Same CDS sequence)	XM_017318264.1 , XM_017318264.2
Accession Version	XM_017318264.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ankyrin repeat domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017318264.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGGTA CCATGGAGGG GCCCGAGGCG GTGCAGAGAG CCACAGAGCT CATCGAGCAG 
CGGCTTGCCC AGGAGGAAGA GACTGAGAAA CTTCGAAGAT CCGCTCCTGG GAAGCTGTCC 
ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGGAAGGG 
GACAGTGCCC TACATGATGC CGTGAGACTC AACCGCTACA AAATCATCAA ACTGCTGCTC 
TTGCATGGGG CGGACATGAT GGCTAAGAAC CTGGCGGGAA AGACCCCCAC GGACCTGGTC 
CAGCTCTGGC AAGCAGACAC CCGGCATGCC CTGGAGCATC CCGAGCCAGA ATCAGAGCAG 
AACGGACTGG AGAGGCCTGG GAGTGGCCGT GAGACACCTC AGCCTATACC AGCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173753.1
CDS	120..1019
Translation	MEGTMEGPEAVQRATELIEQRLAQEEETEKLRRSAPGKLSMDMLVLEEEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAAQEPPPEPEEITGPVNEETFLKAAVEGKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRDKEGDSALHDAVRLNRYKIIKLLLLHGADMMAKNLAGKTPTDLVQLWQADTRHALEHPEPESEQNGLERPGSGRETPQPIPAQ

Target ORF information:

RefSeq Version	XM_017318264.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ankyrin repeat domain 2 (stretch responsive muscle) (Ankrd2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318264.2

ORF Insert Sequence:

ATGGAGGGTA CCATGGAGGG GCCCGAGGCG GTGCAGAGAG CCACAGAGCT CATCGAGCAG 
CGGCTTGCCC AGGAGGAAGA GACTGAGAAA CTTCGAAGAT CCGCTCCTGG GAAGCTGTCC 
ATGGACATGC TAGTGCTAGA GGAAGAGAAG CGCCTCGGGG TTCAGAGTCC TGCTTTACAA 
AAGGTTAAGG GCCAAGAGCG CGTGCGCAAG ACATCCCTGG ACCTGCGACG TGAGATCATT 
GATGTGGGTG GGATCCAGAA CCTCATTGAA CTGAGGAAAA AACGCAAGCA GAAAAAGCGA 
GATGCCCTGG CTGCAGCCCA GGAGCCTCCT CCAGAGCCAG AGGAGATCAC CGGCCCTGTG 
AATGAGGAGA CATTCCTGAA AGCTGCAGTG GAGGGGAAAA TGAAAGTCAT TGACAAGTAC 
CTGGCGGACG GAGGTTCAGC GGACACCTGT GATGAGTTCC GTCGGACAGC ACTGCATCGG 
GCCTCCCTGG AGGGACACAT GGAGATACTG GAGAAACTTC TGGAGAATGG GGCCACCGTG 
GACTTCCAGG ATCGGCTGGA CTGCACAGCC ATGCACTGGG CCTGCCGTGG GGGCCACCTG 
GAGGTGGTGA GACTCCTGCA AAGCCGGGGG GCCGACACCA ACGTGAGAGA CAAGGAAGGG 
GACAGTGCCC TACATGATGC CGTGAGACTC AACCGCTACA AAATCATCAA ACTGCTGCTC 
TTGCATGGGG CGGACATGAT GGCTAAGAAC CTGGCGGGAA AGACCCCCAC GGACCTGGTC 
CAGCTCTGGC AAGCAGACAC CCGGCATGCC CTGGAGCATC CCGAGCCAGA ATCAGAGCAG 
AACGGACTGG AGAGGCCTGG GAGTGGCCGT GAGACACCTC AGCCTATACC AGCCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase).
The Journal of neuroscience : the official journal of the Society for Neuroscience37(10)2709-2722(2017 Mar)
Andrade EC,Musante V,Horiuchi A,Matsuzaki H,Brody AH,Wu T,Greengard P,Taylor JR,Nairn AC

MLP and CARP are linked to chronic PKC? signalling in dilated cardiomyopathy.
Nature communications712120(2016 Jun)
Lange S,Gehmlich K,Lun AS,Blondelle J,Hooper C,Dalton ND,Alvarez EA,Zhang X,Bang ML,Abassi YA,Dos Remedios CG,Peterson KL,Chen J,Ehler E

Ankrd2 is a modulator of NF-?B-mediated inflammatory responses during muscle differentiation.
Cell death & disease5e1002(2014 Jan)
Bean C,Verma NK,Yamamoto DL,Chemello F,Cenni V,Filomena MC,Chen J,Bang ML,Lanfranchi G

The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overload.
PloS one9(4)e93638(2014)
Bang ML,Gu Y,Dalton ND,Peterson KL,Chien KR,Chen J

Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction.
The Journal of biological chemistry288(34)24560-8(2013 Aug)
Mohamed JS,Lopez MA,Cox GA,Boriek AM

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Ankrd2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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