Serinc1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Serinc1
Entrez Gene ID	56442
Full Name	serine incorporator 1
Synonyms	1500011D18Rik,AI315070,AIGP-2,TMS-2,Tde1l,Tde2,Tms2,mKIAA1253
General protein information	Preferred Names serine incorporator 1 Names serine incorporator 1 axotomy induced glycoprotein 2 axotomy-induced glyco/Golgi protein 2 membrane protein TMS-2 tumor differentially expressed 1, like tumor differentially expressed 2 tumor differentially expressed protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 B4

mRNA and Protein(s)

mRNA	Protein	Name
NM_019760.3	NP_062734.1	serine incorporator 1 precursor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	serinc1	NP_956021.1
Saccharomyces cerevisiae (baker's yeast)	TMS1	NP_010390.3
Neurospora crassa	NCU07986	XP_962656.1
Homo sapiens (human)	SERINC1	NP_065806.1
Pan troglodytes (chimpanzee)	SERINC1	XP_518719.2
Caenorhabditis elegans (roundworm)	CELE_R11H6.2	NP_506611.1
Kluyveromyces lactis	KLLA0F11935g	XP_455621.1
Mus musculus (house mouse)	Serinc1	NP_062734.1
Drosophila melanogaster (fruit fly)	TMS1	NP_648893.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002569	XP_312367.5
Caenorhabditis elegans (roundworm)	CELE_Y57E12AL.1	NP_741561.1
Schizosaccharomyces pombe (fission yeast)	SPAPB1A10.07c	NP_593521.1
Xenopus tropicalis (tropical clawed frog)	serinc1	NP_001011399.1
	SERINC1	XP_001109167.2
Canis lupus familiaris (dog)	SERINC1	XP_533483.1
Eremothecium gossypii	AGOS_AGR100W	NP_986766.2
Arabidopsis thaliana (thale cress)	AT3G06170	NP_187268.2
Oryza sativa (rice)	Os03g0454100	NP_001050476.1
Bos taurus (cattle)	SERINC1	NP_001030504.1
Rattus norvegicus (Norway rat)	Serinc1	NP_891996.1
Gallus gallus (chicken)	SERINC1	NP_001026245.1
Magnaporthe oryzae (rice blast fungus)	MGG_15076	XP_003715257.1

Gene Ontology
Bibliography

Related articles in PubMed

Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility.
Chu EP, Elso CM, Pollock AH, Alsayb MA, Mackin L, Thomas HE, Kay TW, Silveira PA, Mansell AS, Gaus K, Brodnicki TC
Molecular immunology8219-33(2017 Feb)

Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes.
Elso CM, Chu EP, Alsayb MA, Mackin L, Ivory ST, Ashton MP, Br?er S, Silveira PA, Brodnicki TC
G3 (Bethesda, Md.)5(12)2903-11(2015 Oct)

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.
Fossat N, Tourle K, Radziewic T, Barratt K, Liebhold D, Studdert JB, Power M, Jones V, Loebel DA, Tam PP
EMBO reports15(8)903-10(2014 Aug)

Characterization of the proneural gene regulatory network during mouse telencephalon development.
Gohlke JM, Armant O, Parham FM, Smith MV, Zimmer C, Castro DS, Nguyen L, Parker JS, Gradwohl G, Portier CJ, Guillemot F
BMC biology615(2008 Mar)

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Nagase T, Ohara O, Koga H
DNA research : an international journal for rapid publication of reports on genes and genomes10(4)167-80(2003 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that Serinc1 is dispensable for certain immune cell functions and does not contribute to previously reported links between lipid composition in immune cells and autoimmunity.
Title: Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility.

The following Serinc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Serinc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11513	NM_019760.3 Latest version!	Mus musculus serine incorporator 1 (Serinc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Serinc1 ( NM_019760.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062734.1 Mus musculus serine incorporator 1 (Serinc1), mRNA.

Price & Availability↑

CloneID	OMu11513
Clone ID Related Accession (Same CDS sequence)	NM_019760.3
Accession Version	NM_019760.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Mus musculus(house mouse)
Product	serine incorporator 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ142862.1, AK141574.1 and CD741076.1. On Jun 19, 2009 this sequence version replaced NM_019760.2. ##Evidence-Data-START## Transcript exon combination :: BC006940.1, SRR1660815.260748.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAGCG TTCTGGGGCT GTGCTCCGTG GCGAGCTGGA TTCCGTGTTT GTGTGGCAGT 
GCCCCGTGTT TGCTGTGCCG ATGCTGCCCC AGTGGGAACA ACTCCACTGT GACTAGATTG 
ATCTACGCAC TTTTCTTGCT CGTCGGAGTA TGTGTAGCTT GTGTAATGTT AATACCAGGA 
ATGGAAGAAC AACTGAATAA GATTCCTGGG TTCTGTGAGA ATGAGAAAGG TGTTGTTCCC 
TGTAATATCC TGGTTGGCTA CAAAGCTGTG TATCGCCTGT GCTTTGGTTT GGCCATGTTC 
TATCTTCTCC TCTCTTTACT AATGATCAAG GTAAAAAGCA GCAGTGACCC TAGAGCGGCA 
GTCCACAATG GATTCTGGTT CTTTAAATTT GCTACAGCAG TTGCAATTAT CATTGGCGCA 
TTCTTCATCC CAGAAGGCAC TTTTACAACT GTGTGGTTTT ATGTAGGCAT GGCGGGCGCC 
TTTTGTTTCA TCCTTATACA ACTAGTCTTA CTTATTGATT TTGCCCATTC TTGGAATGAA 
TCGTGGGTTG AAAAAATGGA AGAAGGGAAC TCAAGATGTT GGTATGCAGC CCTACTGTCA 
GCTACAGCTC TGAATTACTT GCTGTCTTTA GTTGCCGTCG TGCTATTCTT TGTCTACTAC 
ACTCACCCAG CCAGCTGTGC AGAGAACAAG GCGTTCATCA GTGTCAACAT GCTCCTCTGC 
ATTGGCGCCT CAGTAATGTC CATTCTGCCC AAGATCCAGG AATCACAACC AAGGTCTGGC 
TTGTTACAGT CGTCAGTAAT TACAGTCTAC ACAATGTATT TGACATGGTC TGCTATGACC 
AATGAACCAG AAACAAATTG CAATCCAAGT CTACTGAGCA TCATTGGCTT CAATACCACA 
AGGCCTATTC CAAAGGACGG GCAGTCTGTT CAGTGGTGGC ATCCTCAAGG AATTATAGGA 
CTTGTTCTTT TCCTGCTGTG TGTGTTTTAT TCGAGCATCC GTACCTCCAA CAACAGTCAG 
GTTAATAAGC TGACTCTAAC AAGTGATGAG TCAACATTGA TAGAGGATGG GAATGGCAGA 
AGTGACGGAT CACTAGATGA TGGTGATGGC ATCCACCGAG CTGTAGATAA CGAGAGGGAT 
GGAGTCACGT ACAGTTACTC CTTCTTTCAC TTCATGCTCT TCTTGGCTTC ACTTTACATC 
ATGATGACCC TCACCAATTG GTACAGGTAT GAGCCTTCTC GTGAGATGAA AAGTCAGTGG 
ACAGCAGTCT GGGTGAAAAT CTCTTCCAGT TGGATTGGCC TTGTGCTGTA CGTGTGGACA 
CTAGTGGCAC CACTTGTTCT TACAAATCGG GATTTTGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062734.1
CDS	135..1496
Translation	MGSVLGLCSVASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFATAVAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAVVLFFVYYTHPASCAENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGFNTTRPIPKDGQSVQWWHPQGIIGLVLFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGNGRSDGSLDDGDGIHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGLVLYVWTLVAPLVLTNRDFD

Target ORF information:

RefSeq Version	NM_019760.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus serine incorporator 1 (Serinc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019760.3

ORF Insert Sequence:

ATGGGGAGCG TTCTGGGGCT GTGCTCCGTG GCGAGCTGGA TTCCGTGTTT GTGTGGCAGT 
GCCCCGTGTT TGCTGTGCCG ATGCTGCCCC AGTGGGAACA ACTCCACTGT GACTAGATTG 
ATCTACGCAC TTTTCTTGCT CGTCGGAGTA TGTGTAGCTT GTGTAATGTT AATACCAGGA 
ATGGAAGAAC AACTGAATAA GATTCCTGGG TTCTGTGAGA ATGAGAAAGG TGTTGTTCCC 
TGTAATATCC TGGTTGGCTA CAAAGCTGTG TATCGCCTGT GCTTTGGTTT GGCCATGTTC 
TATCTTCTCC TCTCTTTACT AATGATCAAG GTAAAAAGCA GCAGTGACCC TAGAGCGGCA 
GTCCACAATG GATTCTGGTT CTTTAAATTT GCTACAGCAG TTGCAATTAT CATTGGCGCA 
TTCTTCATCC CAGAAGGCAC TTTTACAACT GTGTGGTTTT ATGTAGGCAT GGCGGGCGCC 
TTTTGTTTCA TCCTTATACA ACTAGTCTTA CTTATTGATT TTGCCCATTC TTGGAATGAA 
TCGTGGGTTG AAAAAATGGA AGAAGGGAAC TCAAGATGTT GGTATGCAGC CCTACTGTCA 
GCTACAGCTC TGAATTACTT GCTGTCTTTA GTTGCCGTCG TGCTATTCTT TGTCTACTAC 
ACTCACCCAG CCAGCTGTGC AGAGAACAAG GCGTTCATCA GTGTCAACAT GCTCCTCTGC 
ATTGGCGCCT CAGTAATGTC CATTCTGCCC AAGATCCAGG AATCACAACC AAGGTCTGGC 
TTGTTACAGT CGTCAGTAAT TACAGTCTAC ACAATGTATT TGACATGGTC TGCTATGACC 
AATGAACCAG AAACAAATTG CAATCCAAGT CTACTGAGCA TCATTGGCTT CAATACCACA 
AGGCCTATTC CAAAGGACGG GCAGTCTGTT CAGTGGTGGC ATCCTCAAGG AATTATAGGA 
CTTGTTCTTT TCCTGCTGTG TGTGTTTTAT TCGAGCATCC GTACCTCCAA CAACAGTCAG 
GTTAATAAGC TGACTCTAAC AAGTGATGAG TCAACATTGA TAGAGGATGG GAATGGCAGA 
AGTGACGGAT CACTAGATGA TGGTGATGGC ATCCACCGAG CTGTAGATAA CGAGAGGGAT 
GGAGTCACGT ACAGTTACTC CTTCTTTCAC TTCATGCTCT TCTTGGCTTC ACTTTACATC 
ATGATGACCC TCACCAATTG GTACAGGTAT GAGCCTTCTC GTGAGATGAA AAGTCAGTGG 
ACAGCAGTCT GGGTGAAAAT CTCTTCCAGT TGGATTGGCC TTGTGCTGTA CGTGTGGACA 
CTAGTGGCAC CACTTGTTCT TACAAATCGG GATTTTGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility.
Molecular immunology8219-33(2017 Feb)
Chu EP,Elso CM,Pollock AH,Alsayb MA,Mackin L,Thomas HE,Kay TW,Silveira PA,Mansell AS,Gaus K,Brodnicki TC

Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes.
G3 (Bethesda, Md.)5(12)2903-11(2015 Oct)
Elso CM,Chu EP,Alsayb MA,Mackin L,Ivory ST,Ashton MP,Br?er S,Silveira PA,Brodnicki TC

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.
EMBO reports15(8)903-10(2014 Aug)
Fossat N,Tourle K,Radziewic T,Barratt K,Liebhold D,Studdert JB,Power M,Jones V,Loebel DA,Tam PP

Characterization of the proneural gene regulatory network during mouse telencephalon development.
BMC biology615(2008 Mar)
Gohlke JM,Armant O,Parham FM,Smith MV,Zimmer C,Castro DS,Nguyen L,Parker JS,Gradwohl G,Portier CJ,Guillemot F

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
DNA research : an international journal for rapid publication of reports on genes and genomes10(4)167-80(2003 Aug)
Okazaki N,Kikuno R,Ohara R,Inamoto S,Koseki H,Hiraoka S,Saga Y,Nagase T,Ohara O,Koga H

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Serinc1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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