Snx1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snx1
Entrez Gene ID	56440
Full Name	sorting nexin 1
General protein information	Preferred Names sorting nexin 1 Names sorting nexin-1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 C

mRNA and Protein(s)

mRNA	Protein	Name
NM_019727.2	NP_062701.2	sorting nexin-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SNX1	XP_003314756.1
Bos taurus (cattle)	SNX1	NP_001039572.2
Rattus norvegicus (Norway rat)	Snx1	NP_445863.1
Homo sapiens (human)	SNX1	NP_003090.2
	SNX1	XP_001106400.1
Gallus gallus (chicken)	SNX1	XP_004943678.1
Canis lupus familiaris (dog)	SNX1	XP_535509.2
Xenopus tropicalis (tropical clawed frog)	snx1	XP_002938918.1
Mus musculus (house mouse)	Snx1	NP_062701.2
Danio rerio (zebrafish)	snx1a	NP_001122143.2
Danio rerio (zebrafish)	LOC100331408	XP_002666830.3

Gene Ontology
Bibliography

Related articles in PubMed

EFA6A, a guanine nucleotide exchange factor for Arf6, interacts with sorting nexin-1 and regulates neurite outgrowth.
Fukaya M, Fukushima D, Hara Y, Sakagami H
Journal of neurochemistry129(1)21-36(2014 Apr)

Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice.
Villar VA, Jones JE, Armando I, Asico LD, Escano CS Jr, Lee H, Wang X, Yang Y, Pascua-Crusan AM, Palmes-Saloma CP, Felder RA, Jose PA
The Journal of biological chemistry288(1)152-63(2013 Jan)

SNX5 is essential for efficient macropinocytosis and antigen processing in primary macrophages.
Lim JP, Teasdale RD, Gleeson PA
Biology open1(9)904-14(2012 Sep)

Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos.
Kawamura N, Sun-Wada GH, Aoyama M, Harada A, Takasuga S, Sasaki T, Wada Y
Nature communications31071(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SNX1 interacts with Arf6 to mediate neurite formation which is regulated by EFA6A.
Title: EFA6A, a guanine nucleotide exchange factor for Arf6, interacts with sorting nexin-1 and regulates neurite outgrowth.

SNX1 has a crucial role in D(5)R trafficking and SNX1 depletion results in D(5)R dysfunction and thus may represent a novel mechanism for the pathogenesis of essential hypertension
Title: Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice.

A RUN Domain from DENND5/Rab6IP1 binds sorting Nexin 1 and is involved in the trafficking of vesicles at the level of Golgi.
Title: Mapping the interactions between a RUN domain from DENND5/Rab6IP1 and sorting nexin 1.

Data describe a functional interaction between Hbeta58, sorting nexin 1 (SNX1), and SNX2 and strongly suggest that SNX2 plays a more critical role than SNX1 in retromer activity during embryonic development.
Title: Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2.

HkRP1 is involved in the process of tubulation of sorting nexin-1 positive membranes from early endosome subdomains
Title: A novel hook-related protein family and the characterization of hook-related protein 1.

The following Snx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu22090	NM_019727.2 Latest version!	Mus musculus sorting nexin 1 (Snx1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snx1 ( NM_019727.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062701.2 Mus musculus sorting nexin 1 (Snx1), mRNA.

Price & Availability↑

CloneID	OMu22090
Clone ID Related Accession (Same CDS sequence)	NM_019727.2
Accession Version	NM_019727.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	sorting nexin-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF154120.1, AB019214.1, BC066189.1 and BB198783.1. On Jul 21, 2005 this sequence version replaced NM_019727.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF154120.1, AK168742.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCAG GAGGTGGTGG CTGTAGCGCT TCGGAGCGAC TCCCTCCGCC CTTCCCTGGC 
ATGGATCCGG AGTCGGAAGG GGCTGCCGGG GGGTCAGAAC CCGAGGCTGG GGACAGCGAC 
ACCGAGGGGG AGGATATTTT CACTGGCGCC GCGGCAGCCA CTAAGCCCCA GTCTCCAAAG 
AAAACCACAT CCCTTTTTCC TATCAAAAAT GGTTCCAAAG AGAATGGGAT CCATGAGGAC 
CAAGACCAAG AGCCACAGGA TCTCTTTGCA GATGCCACAG TGGAACTATC CCTGGACAGC 
ACACAGAATA ACCAGAAGAC AATGCCAGGC AAAACCCTTA CTTCTCATCC TCCGCAAGAA 
GCCACAAATT CTCCGAAGCC ACAGCCAAGC TATGAGGAGC TGGAGGAAGA ACAGGAGGAT 
CAGTTTGATT TGACAGTTGG TATCACCGAT CCTGAGAAGA TCGGGGATGG TATGAATGCC 
TATGTAGCCT ACAAAGTCAC CACACAGACA AGCTTACCGA TGTTCAGAAG TAGGCAGTTT 
GCAGTGAAAA GAAGATTCAG TGACTTCCTG GGTCTTTATG AGAAGCTTTC AGAGAAGCAC 
TCCCAGAATG GTTTCATTGT GCCTCCTCCA CCCGAGAAGA GCCTAATAGG AATGACAAAG 
GTGAAGGTTG GGAAGGAAGA TTCTTCTTCC GCAGAGTTTC TTGAGAAACG GAGGGCTGCT 
TTGGAAAGGT ACCTTCAAAG AATTGTGAAT CATCCCACCA TGTTACAGGA CCCAGATGTC 
AGGGAGTTTC TGGAAAAAGA AGAGCTGCCT CGAGCTGTGG GCACGCAGGC TTTGAGTGGC 
GCTGGTCTCC TTAAGATGTT CAACAAAGCT ACAGATGCAG TCAGCAAAAT GACCATCAAG 
ATGAATGAAT CAGACATTTG GTTCGAGGAG AAACTCCAGG AGGTAGAGTG TGAGGAGCAG 
CGCCTACGGA AGCTGCATGC TGTGGTGGAG ACTCTAGTCA ACCATAGGAA AGAACTAGCG 
CTGAACACAG CCCTGTTTGC CAAGAGTCTA GCCATGCTTG GGAGCTCCGA GGACAACACA 
GCACTTTCTC GAGCGCTCTC CCAACTGGCT GAGGTGGAAG AAAAGATTGA GCAGCTCCAC 
CAGGAACAGG CCAACAATGA CTTCTTCCTC CTTGCTGAAC TCCTGAGTGA CTATATTCGC 
CTCCTGGCCA TTGTCCGAGC TGCCTTCGAC CAGCGCATGA AGACATGGCA GCGCTGGCAG 
GATGCTCAAG CCACGCTGCA GAAGAAGCGG GAGTCTGAGG CACGGCTGCT GTGGGCCAAC 
AAGCCTGACA AACTGCAGCA GGCTAAGGAT GAGATCACAG AGTGGGAATC TCGGGTGACT 
CAGTATGAAA GGGACTTTGA AAGGATTTCC ACAGTTGTCC GAAAGGAAGT GACACGATTT 
GAGAAAGAGA AGTCCAAGGA TTTCAAAAAC CACGTGATGA AGTACCTGGA GACACTCCTA 
CATTCCCAGC AGCAGCTGGC AAAATACTGG GAAGCCTTCC TTCCTGAGGC AAAGGCCATC 
TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062701.2
CDS	122..1687
Translation	MASGGGGCSASERLPPPFPGMDPESEGAAGGSEPEAGDSDTEGEDIFTGAAAATKPQSPKKTTSLFPIKNGSKENGIHEDQDQEPQDLFADATVELSLDSTQNNQKTMPGKTLTSHPPQEATNSPKPQPSYEELEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPMFRSRQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQALSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTALFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKRESEARLLWANKPDKLQQAKDEITEWESRVTQYERDFERISTVVRKEVTRFEKEKSKDFKNHVMKYLETLLHSQQQLAKYWEAFLPEAKAIS

Target ORF information:

RefSeq Version	NM_019727.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sorting nexin 1 (Snx1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019727.2

ORF Insert Sequence:

ATGGCGTCAG GAGGTGGTGG CTGTAGCGCT TCGGAGCGAC TCCCTCCGCC CTTCCCTGGC 
ATGGATCCGG AGTCGGAAGG GGCTGCCGGG GGGTCAGAAC CCGAGGCTGG GGACAGCGAC 
ACCGAGGGGG AGGATATTTT CACTGGCGCC GCGGCAGCCA CTAAGCCCCA GTCTCCAAAG 
AAAACCACAT CCCTTTTTCC TATCAAAAAT GGTTCCAAAG AGAATGGGAT CCATGAGGAC 
CAAGACCAAG AGCCACAGGA TCTCTTTGCA GATGCCACAG TGGAACTATC CCTGGACAGC 
ACACAGAATA ACCAGAAGAC AATGCCAGGC AAAACCCTTA CTTCTCATCC TCCGCAAGAA 
GCCACAAATT CTCCGAAGCC ACAGCCAAGC TATGAGGAGC TGGAGGAAGA ACAGGAGGAT 
CAGTTTGATT TGACAGTTGG TATCACCGAT CCTGAGAAGA TCGGGGATGG TATGAATGCC 
TATGTAGCCT ACAAAGTCAC CACACAGACA AGCTTACCGA TGTTCAGAAG TAGGCAGTTT 
GCAGTGAAAA GAAGATTCAG TGACTTCCTG GGTCTTTATG AGAAGCTTTC AGAGAAGCAC 
TCCCAGAATG GTTTCATTGT GCCTCCTCCA CCCGAGAAGA GCCTAATAGG AATGACAAAG 
GTGAAGGTTG GGAAGGAAGA TTCTTCTTCC GCAGAGTTTC TTGAGAAACG GAGGGCTGCT 
TTGGAAAGGT ACCTTCAAAG AATTGTGAAT CATCCCACCA TGTTACAGGA CCCAGATGTC 
AGGGAGTTTC TGGAAAAAGA AGAGCTGCCT CGAGCTGTGG GCACGCAGGC TTTGAGTGGC 
GCTGGTCTCC TTAAGATGTT CAACAAAGCT ACAGATGCAG TCAGCAAAAT GACCATCAAG 
ATGAATGAAT CAGACATTTG GTTCGAGGAG AAACTCCAGG AGGTAGAGTG TGAGGAGCAG 
CGCCTACGGA AGCTGCATGC TGTGGTGGAG ACTCTAGTCA ACCATAGGAA AGAACTAGCG 
CTGAACACAG CCCTGTTTGC CAAGAGTCTA GCCATGCTTG GGAGCTCCGA GGACAACACA 
GCACTTTCTC GAGCGCTCTC CCAACTGGCT GAGGTGGAAG AAAAGATTGA GCAGCTCCAC 
CAGGAACAGG CCAACAATGA CTTCTTCCTC CTTGCTGAAC TCCTGAGTGA CTATATTCGC 
CTCCTGGCCA TTGTCCGAGC TGCCTTCGAC CAGCGCATGA AGACATGGCA GCGCTGGCAG 
GATGCTCAAG CCACGCTGCA GAAGAAGCGG GAGTCTGAGG CACGGCTGCT GTGGGCCAAC 
AAGCCTGACA AACTGCAGCA GGCTAAGGAT GAGATCACAG AGTGGGAATC TCGGGTGACT 
CAGTATGAAA GGGACTTTGA AAGGATTTCC ACAGTTGTCC GAAAGGAAGT GACACGATTT 
GAGAAAGAGA AGTCCAAGGA TTTCAAAAAC CACGTGATGA AGTACCTGGA GACACTCCTA 
CATTCCCAGC AGCAGCTGGC AAAATACTGG GAAGCCTTCC TTCCTGAGGC AAAGGCCATC 
TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

EFA6A, a guanine nucleotide exchange factor for Arf6, interacts with sorting nexin-1 and regulates neurite outgrowth.
Journal of neurochemistry129(1)21-36(2014 Apr)
Fukaya M,Fukushima D,Hara Y,Sakagami H

Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice.
The Journal of biological chemistry288(1)152-63(2013 Jan)
Villar VA,Jones JE,Armando I,Asico LD,Escano CS Jr,Lee H,Wang X,Yang Y,Pascua-Crusan AM,Palmes-Saloma CP,Felder RA,Jose PA

SNX5 is essential for efficient macropinocytosis and antigen processing in primary macrophages.
Biology open1(9)904-14(2012 Sep)
Lim JP,Teasdale RD,Gleeson PA

Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos.
Nature communications31071(2012)
Kawamura N,Sun-Wada GH,Aoyama M,Harada A,Takasuga S,Sasaki T,Wada Y

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Snx1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報