Dpt cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dpt
Entrez Gene ID	56429
Full Name	dermatopontin
Synonyms	1810032B19Rik,5033416F05Rik,EQ-1,Eq1
General protein information	Preferred Names dermatopontin Names dermatopontin TRAMP early quiescence protein-1 tyrosine-rich acidic matrix protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 H2.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_019759.2	NP_062733.1	dermatopontin precursor
NM_019759.3	NP_062733.1	dermatopontin precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	DPT	NP_001039368.1
Homo sapiens (human)	DPT	NP_001928.2
Pan troglodytes (chimpanzee)	DPT	XP_001135049.1
Gallus gallus (chicken)	DPT	XP_001231676.2
Canis lupus familiaris (dog)	DPT	XP_547476.1
Xenopus tropicalis (tropical clawed frog)	dpt	NP_001025599.1
Danio rerio (zebrafish)	si:dkey-98p3.2	NP_001025256.2
Mus musculus (house mouse)	Dpt	NP_062733.1

Gene Ontology
Bibliography

Related articles in PubMed

Dermatopontin in Bone Marrow Extracellular Matrix Regulates Adherence but Is Dispensable for Murine Hematopoietic Cell Maintenance.
Kramer AC, Blake AL, Taisto ME, Lehrke MJ, Webber BR, Lund TC
Stem cell reports9(3)770-778(2017 Sep)

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.
Kosfeld A, Brand F, Weiss AC, Kreuzer M, Goerk M, Martens H, Schubert S, Sch?fer AK, Riehmer V, Hennies I, Br?sen JH, Pape L, Amann K, Krogvold L, Bjerre A, Daniel C, Kispert A, Haffner D, Weber RG
Human molecular genetics26(9)1716-1731(2017 05)

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO
Scientific reports740495(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings illustrate a previously uncharacterized role of Dpt in maintaining hematopoietic stem cells ex vivo.
Title: Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification.

DPT may affect testicular function by affecting the integrity of the bloodtestis barrier.
Title: Increased expression of dermatopontin and its implications for testicular dysfunction in mice.

The DP-4 peptide activated Fn and enhanced cell adhesion activity
Title: Identification of fibronectin binding sites in dermatopontin and their biological function.

The present study provides the first evidence that DPT may be a novel effector of cadmium chloride, highlighting the significant role of DPT in the regulation of claudin-11 expression
Title: Dermatopontin is a novel regulator of the CdCl2-induced decrease in claudin-11 expression.

Aging in the mdx diaphragm seems to be associated with a drastic increase in extracellular matrix proteins incliding dermatopontin.
Title: Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy.

The following Dpt gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dpt cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11495	NM_019759.3 Latest version!	Mus musculus dermatopontin (Dpt), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
View Old Accession Versions >>
OMu11495	NM_019759.2	Mus musculus dermatopontin (Dpt), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dpt ( NM_019759.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062733.1 Mus musculus dermatopontin (Dpt), mRNA.

Price & Availability↑

CloneID	OMu11495
Clone ID Related Accession (Same CDS sequence)	NM_019759.2 , NM_019759.3
Accession Version	NM_019759.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-09
Organism	Mus musculus(house mouse)
Product	dermatopontin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC137884.9. On Nov 17, 2006 this sequence version replaced NM_019759.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF143374.1, BC046420.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTCA CTCTTCTGTG GGTTCTTCTG CCACTGGTGA CCACAGCCTG GGGCCAGTAT 
GGTGGCTACG GGTACCCATA CCAGCAGTAC CAGGACTACG GTGATGATGG ATGGGTGAAT 
CTTAACCGCC AAGGCTTCAG CTACCAGTGT CCCCACGGGC AAGTGGTGGT AGCTGTGAGG 
AGCATCTTTA GCAAGAAGGA AGGCTCTGAC AGACAATGGA ACTATGCCTG CATGCCTACA 
CCCCAAAGCC TGGGGGAGCC CACTGAGTGC TGGTGGGAGG AGATCAACAG GGCCGGCATG 
GAATGGTACC AGAAGTGCTC CAACAATGGA TTGGTGGCGG GGTTCCAGAG CCGCTACTTC 
GAATCAGTGC TGGATCGTGA GTGGCAATTT TACTGCTGCC GCTATAGCAA GAGGTGTCCA 
TATTCCTGCT GGATGACAAC AGAGTACCCA AGCCACTATG GGGAAGACAT GGACATGATT 
TCCTATGACT ACGATTTTTA TATGCGAGGA GCAACAACCA CTTTCTCTGC AGTGGAAAGG 
GATCGCCAGT GGAAGTTCAT CATGTGCCGG ATGACTGACT ACGACTGCGA ATTCGAAAAC 
GTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062733.1
CDS	1..606
Translation	MDLTLLWVLLPLVTTAWGQYGGYGYPYQQYQDYGDDGWVNLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDMISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV

Target ORF information:

RefSeq Version	NM_019759.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus dermatopontin (Dpt), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019759.2

ORF Insert Sequence:

ATGGACCTCA CTCTTCTGTG GGTTCTTCTG CCACTGGTGA CCACAGCCTG GGGCCAGTAT 
GGTGGCTACG GGTACCCATA CCAGCAGTAC CAGGACTACG GTGATGATGG ATGGGTGAAT 
CTTAACCGCC AAGGCTTCAG CTACCAGTGT CCCCACGGGC AAGTGGTGGT AGCTGTGAGG 
AGCATCTTTA GCAAGAAGGA AGGCTCTGAC AGACAATGGA ACTATGCCTG CATGCCTACA 
CCCCAAAGCC TGGGGGAGCC CACTGAGTGC TGGTGGGAGG AGATCAACAG GGCCGGCATG 
GAATGGTACC AGAAGTGCTC CAACAATGGA TTGGTGGCGG GGTTCCAGAG CCGCTACTTC 
GAATCAGTGC TGGATCGTGA GTGGCAATTT TACTGCTGCC GCTATAGCAA GAGGTGTCCA 
TATTCCTGCT GGATGACAAC AGAGTACCCA AGCCACTATG GGGAAGACAT GGACATGATT 
TCCTATGACT ACGATTTTTA TATGCGAGGA GCAACAACCA CTTTCTCTGC AGTGGAAAGG 
GATCGCCAGT GGAAGTTCAT CATGTGCCGG ATGACTGACT ACGACTGCGA ATTCGAAAAC 
GTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dpt ( NM_019759.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062733.1 Mus musculus dermatopontin (Dpt), mRNA.

Price & Availability↑

CloneID	OMu11495
Clone ID Related Accession (Same CDS sequence)	NM_019759.2 , NM_019759.3
Accession Version	NM_019759.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Mus musculus(house mouse)
Product	dermatopontin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC137884.9. On Feb 17, 2018 this sequence version replaced NM_019759.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC046420.1, AF143374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCTCA CTCTTCTGTG GGTTCTTCTG CCACTGGTGA CCACAGCCTG GGGCCAGTAT 
GGTGGCTACG GGTACCCATA CCAGCAGTAC CAGGACTACG GTGATGATGG ATGGGTGAAT 
CTTAACCGCC AAGGCTTCAG CTACCAGTGT CCCCACGGGC AAGTGGTGGT AGCTGTGAGG 
AGCATCTTTA GCAAGAAGGA AGGCTCTGAC AGACAATGGA ACTATGCCTG CATGCCTACA 
CCCCAAAGCC TGGGGGAGCC CACTGAGTGC TGGTGGGAGG AGATCAACAG GGCCGGCATG 
GAATGGTACC AGAAGTGCTC CAACAATGGA TTGGTGGCGG GGTTCCAGAG CCGCTACTTC 
GAATCAGTGC TGGATCGTGA GTGGCAATTT TACTGCTGCC GCTATAGCAA GAGGTGTCCA 
TATTCCTGCT GGATGACAAC AGAGTACCCA AGCCACTATG GGGAAGACAT GGACATGATT 
TCCTATGACT ACGATTTTTA TATGCGAGGA GCAACAACCA CTTTCTCTGC AGTGGAAAGG 
GATCGCCAGT GGAAGTTCAT CATGTGCCGG ATGACTGACT ACGACTGCGA ATTCGAAAAC 
GTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062733.1
CDS	70..675
Translation	MDLTLLWVLLPLVTTAWGQYGGYGYPYQQYQDYGDDGWVNLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDMISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV

Target ORF information:

RefSeq Version	NM_019759.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus dermatopontin (Dpt), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019759.3

ORF Insert Sequence:

ATGGACCTCA CTCTTCTGTG GGTTCTTCTG CCACTGGTGA CCACAGCCTG GGGCCAGTAT 
GGTGGCTACG GGTACCCATA CCAGCAGTAC CAGGACTACG GTGATGATGG ATGGGTGAAT 
CTTAACCGCC AAGGCTTCAG CTACCAGTGT CCCCACGGGC AAGTGGTGGT AGCTGTGAGG 
AGCATCTTTA GCAAGAAGGA AGGCTCTGAC AGACAATGGA ACTATGCCTG CATGCCTACA 
CCCCAAAGCC TGGGGGAGCC CACTGAGTGC TGGTGGGAGG AGATCAACAG GGCCGGCATG 
GAATGGTACC AGAAGTGCTC CAACAATGGA TTGGTGGCGG GGTTCCAGAG CCGCTACTTC 
GAATCAGTGC TGGATCGTGA GTGGCAATTT TACTGCTGCC GCTATAGCAA GAGGTGTCCA 
TATTCCTGCT GGATGACAAC AGAGTACCCA AGCCACTATG GGGAAGACAT GGACATGATT 
TCCTATGACT ACGATTTTTA TATGCGAGGA GCAACAACCA CTTTCTCTGC AGTGGAAAGG 
GATCGCCAGT GGAAGTTCAT CATGTGCCGG ATGACTGACT ACGACTGCGA ATTCGAAAAC 
GTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dermatopontin in Bone Marrow Extracellular Matrix Regulates Adherence but Is Dispensable for Murine Hematopoietic Cell Maintenance.
Stem cell reports9(3)770-778(2017 Sep)
Kramer AC,Blake AL,Taisto ME,Lehrke MJ,Webber BR,Lund TC

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.
Human molecular genetics26(9)1716-1731(2017 05)
Kosfeld A,Brand F,Weiss AC,Kreuzer M,Goerk M,Martens H,Schubert S,Sch?fer AK,Riehmer V,Hennies I,Br?sen JH,Pape L,Amann K,Krogvold L,Bjerre A,Daniel C,Kispert A,Haffner D,Weber RG

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Scientific reports740495(2017 Jan)
Naba A,Clauser KR,Mani DR,Carr SA,Hynes RO

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Dpt cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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