Cbln3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cbln3
Entrez Gene ID	56410
Full Name	cerebellin 3 precursor protein
General protein information	Preferred Names cerebellin 3 precursor protein Names cerebellin-3 precerebellin 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14 C3\|14 28.19 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_019820.3	NP_062794.1	cerebellin-3 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cbln3	NP_062794.1
Rattus norvegicus (Norway rat)	Cbln3	NP_001102800.1
	CBLN3	XP_001114278.1
Bos taurus (cattle)	CBLN3	NP_001073071.1
Homo sapiens (human)	CBLN3	NP_001034860.1
Pan troglodytes (chimpanzee)	CBLN3	XP_001170186.1
Canis lupus familiaris (dog)	CBLN3	XP_547748.2

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.
Deans MR, Peterson JM, Wong GW
PloS one5(9)e12765(2010 Sep)

A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ
Nature biotechnology28(7)749-55(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

immunohistochemical localization suggests the basis for anatomical convergence of the Cbln-GluRdelta2 signaling pathway in parallel fiber-Purkinje cell synapses
Title: Cbln1 accumulates and colocalizes with Cbln3 and GluRdelta2 at parallel fiber-Purkinje cell synapses in the mouse cerebellum.

Cbln3 is a secreted glycoprotein that participates in heteromeric complexes with Cbln1.
Title: Cbln1 is essential for interaction-dependent secretion of Cbln3.

The following Cbln3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cbln3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11468	NM_019820.3 Latest version!	Mus musculus cerebellin 3 precursor protein (Cbln3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cbln3 ( NM_019820.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062794.1 Mus musculus cerebellin 3 precursor protein (Cbln3), mRNA.

Price & Availability↑

CloneID	OMu11468
Clone ID Related Accession (Same CDS sequence)	NM_019820.3
Accession Version	NM_019820.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 594bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	cerebellin-3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC098877.3. On Nov 17, 2006 this sequence version replaced NM_019820.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC065108.1, SRR1660811.74297.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849377 [ECO:0000348] ##Evidence-Data-END##

ATGGGGACGG AATGGCACAA ACCCAAGCTG TCCTTGGCCC TGGTGCTTCT GACCCTGGAG 
GCTGGGTGGG CTCAAGAAGG GTCAGAGCCT GTCCTACTGG AGGGGGAGTG CCTGGTGGTC 
TGTGAGCCAG GCCGACCTAC TGCAGGAGGA CCTGGGGGTG CAGCCCTGGG AGAGGCACCC 
CCAGGACGAG TGGCGTTTGC TGCAGTCCGA AGCCATCACC ATGAACCAGC AGGAGAAACC 
GGCAACGGTA CCAGTGGTGC CATCTACTTC GACCAGGTAC TGGTCAATGA GGGCGAGGGC 
TTTGATCGGA CCTCGGGCTG CTTCGTGGCC CCTGTCCGTG GAGTCTACAG CTTCCGATTC 
CACGTGGTCA AGGTGTACAA CCGCCAAACT GTCCAGGTGA GTCTGATGCT GAACACATGG 
CCGGTCATCT CAGCCTTTGC AAATGACCCT GATGTGACCC GAGAGGCAGC CACAAGCTCT 
GTGCTGCTTC CCCTGGACCC GGGGGACCGT GTGTCCCTGC GCCTGCGTCG GGGGAATCTT 
CTGGGTGGCT GGAAGTATTC GAGCTTCTCA GGCTTCCTCA TCTTCCCACT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062794.1
CDS	70..663
Translation	MGTEWHKPKLSLALVLLTLEAGWAQEGSEPVLLEGECLVVCEPGRPTAGGPGGAALGEAPPGRVAFAAVRSHHHEPAGETGNGTSGAIYFDQVLVNEGEGFDRTSGCFVAPVRGVYSFRFHVVKVYNRQTVQVSLMLNTWPVISAFANDPDVTREAATSSVLLPLDPGDRVSLRLRRGNLLGGWKYSSFSGFLIFPL

Target ORF information:

RefSeq Version	NM_019820.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cerebellin 3 precursor protein (Cbln3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019820.3

ORF Insert Sequence:

ATGGGGACGG AATGGCACAA ACCCAAGCTG TCCTTGGCCC TGGTGCTTCT GACCCTGGAG 
GCTGGGTGGG CTCAAGAAGG GTCAGAGCCT GTCCTACTGG AGGGGGAGTG CCTGGTGGTC 
TGTGAGCCAG GCCGACCTAC TGCAGGAGGA CCTGGGGGTG CAGCCCTGGG AGAGGCACCC 
CCAGGACGAG TGGCGTTTGC TGCAGTCCGA AGCCATCACC ATGAACCAGC AGGAGAAACC 
GGCAACGGTA CCAGTGGTGC CATCTACTTC GACCAGGTAC TGGTCAATGA GGGCGAGGGC 
TTTGATCGGA CCTCGGGCTG CTTCGTGGCC CCTGTCCGTG GAGTCTACAG CTTCCGATTC 
CACGTGGTCA AGGTGTACAA CCGCCAAACT GTCCAGGTGA GTCTGATGCT GAACACATGG 
CCGGTCATCT CAGCCTTTGC AAATGACCCT GATGTGACCC GAGAGGCAGC CACAAGCTCT 
GTGCTGCTTC CCCTGGACCC GGGGGACCGT GTGTCCCTGC GCCTGCGTCG GGGGAATCTT 
CTGGGTGGCT GGAAGTATTC GAGCTTCTCA GGCTTCCTCA TCTTCCCACT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.
PloS one5(9)e12765(2010 Sep)
Deans MR,Peterson JM,Wong GW

A mouse knockout library for secreted and transmembrane proteins.
Nature biotechnology28(7)749-55(2010 Jul)
Tang T,Li L,Tang J,Li Y,Lin WY,Martin F,Grant D,Solloway M,Parker L,Ye W,Forrest W,Ghilardi N,Oravecz T,Platt KA,Rice DS,Hansen GM,Abuin A,Eberhart DE,Godowski P,Holt KH,Peterson A,Zambrowicz BP,de Sauvage FJ

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Cbln3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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