Arl3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arl3
Entrez Gene ID	56350
Full Name	ADP-ribosylation factor-like 3
General protein information	Preferred Names ADP-ribosylation factor-like 3 Names ADP-ribosylation factor-like protein 3 ADP-ribosylation-like 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_019718.2	NP_062692.1	ADP-ribosylation factor-like protein 3
XM_006527223.2	XP_006527286.1	ADP-ribosylation factor-like protein 3 isoform X1
NM_001355233.1	NP_001342162.1	ADP-ribosylation factor-like protein 3 isoform 2
NM_019718.3	NP_062692.1	ADP-ribosylation factor-like protein 3 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ARL3	XP_508005.1
Danio rerio (zebrafish)	arl3	NP_001038373.1
Caenorhabditis elegans (roundworm)	arl-3	NP_497037.1
Canis lupus familiaris (dog)	ARL3	XP_003640041.1
Rattus norvegicus (Norway rat)	Arl3	NP_073191.1
Gallus gallus (chicken)	ARL3	XP_421730.1
Drosophila melanogaster (fruit fly)	dnd	NP_650995.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004496	XP_313793.5
Bos taurus (cattle)	ARL3	NP_001033656.1
Xenopus tropicalis (tropical clawed frog)	arl3	XP_002938771.2
Homo sapiens (human)	ARL3	NP_004302.1
Mus musculus (house mouse)	Arl3	NP_062692.1

Gene Ontology
Bibliography

Related articles in PubMed

Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).
Ivanova AA, Caspary T, Seyfried NT, Duong DM, West AB, Liu Z, Kahn RA
The Journal of biological chemistry292(26)11091-11108(2017 06)

ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment.
Wright ZC, Singh RK, Alpino R, Goldberg AF, Sokolov M, Ramamurthy V
Human molecular genetics25(10)2031-2044(2016 05)

PDE6?-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.
Fansa EK, K?sling SK, Zent E, Wittinghofer A, Ismail S
Nature communications711366(2016 Apr)

Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.
Hanke-Gogokhia C, Wu Z, Gerstner CD, Frederick JM, Zhang H, Baehr W
The Journal of biological chemistry291(13)7142-55(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).(
Title: Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).

this study identifies ARL3 as a key player in prenylated protein trafficking in rod photoreceptor cells and establishes the potential role for ARL3 dysregulation in the pathogenesis of RP2-related forms of X-linked retinitis pigmentosa
Title: ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment.

ARL3 regulates protein trafficking and ciliogenesis in mouse photoreceptors.
Title: Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.

Studies indicate that Arf-like proteins ARL2 and ARL3 are not substrates for N-myristoyl transferase.
Title: The Function of Arf-like Proteins ARL2 and ARL3 in Photoreceptors.

The authors show that the ciliary G-protein Arl13B, mutated in Joubert syndrome, is the guanine nucleotide exchange factor for Arl3, and its function is conserved in evolution
Title: A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins.

The following Arl3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arl3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu55657	NM_001355233.1 Latest version!	Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu55657	XM_006527223.2 Latest version!	Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu21716	NM_019718.3 Latest version!	Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OMu21716	NM_019718.2	Mus musculus ADP-ribosylation factor-like 3 (Arl3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arl3 ( NM_001355233.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001342162.1 Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu55657
Clone ID Related Accession (Same CDS sequence)	XM_006527223.2 , NM_001355233.1
Accession Version	NM_001355233.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 3 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC156982.8. On Sep 13, 2017 this sequence version replaced XM_006527223.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.386348.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383, SAMN00849390 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGACGTGTCG CAGCGCTGTG TGGACCAGTC ACTCCTGCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342162.1
CDS	141..683
Translation	MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDVSQRCVDQSLLL

Target ORF information:

RefSeq Version	NM_001355233.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355233.1

ORF Insert Sequence:

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGACGTGTCG CAGCGCTGTG TGGACCAGTC ACTCCTGCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arl3 ( XM_006527223.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006527286.1 Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu55657
Clone ID Related Accession (Same CDS sequence)	XM_006527223.2 , NM_001355233.1
Accession Version	XM_006527223.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	ADP-ribosylation factor-like protein 3 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000085.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006527223.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGACGTGTCG CAGCGCTGTG TGGACCAGTC ACTCCTGCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006527286.1
CDS	140..682
Translation	MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDVSQRCVDQSLLL

Target ORF information:

RefSeq Version	XM_006527223.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006527223.2

ORF Insert Sequence:

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGACGTGTCG CAGCGCTGTG TGGACCAGTC ACTCCTGCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arl3 ( NM_019718.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062692.1 Mus musculus ADP-ribosylation factor-like 3 (Arl3), mRNA.

Price & Availability↑

CloneID	OMu21716
Clone ID Related Accession (Same CDS sequence)	NM_019718.2 , NM_019718.3
Accession Version	NM_019718.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-25
Organism	Mus musculus(House mouse)
Product	ADP-ribosylation factor-like protein 3
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC042941.1. On Dec 20, 2003 this sequence version replaced NM_019718.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC042941.1, BU520638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGATGGCATG AACTGGGTCT GCAAGAATGT CAACGCAAAG 
AAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062692.1
CDS	44..592
Translation	MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK

Target ORF information:

RefSeq Version	NM_019718.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus ADP-ribosylation factor-like 3 (Arl3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019718.2

ORF Insert Sequence:

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGATGGCATG AACTGGGTCT GCAAGAATGT CAACGCAAAG 
AAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arl3 ( NM_019718.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062692.1 Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu21716
Clone ID Related Accession (Same CDS sequence)	NM_019718.2 , NM_019718.3
Accession Version	NM_019718.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC156982.8. On Sep 13, 2017 this sequence version replaced NM_019718.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC042941.1, BU520638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGATGGCATG AACTGGGTCT GCAAGAATGT CAACGCAAAG 
AAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062692.1
CDS	141..689
Translation	MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK

Target ORF information:

RefSeq Version	NM_019718.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 3 (Arl3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019718.3

ORF Insert Sequence:

ATGGGCTTGC TCTCTATTTT GCGCAAATTG AAAAGTGCAC CAGACCAGGA GGTGCGAATC 
CTACTCCTGG GCTTGGACAA CGCGGGCAAG ACTACCTTGC TGAAGCAACT CGCATCTGAA 
GACATCAGCC ACATCACACC TACACAGGGA TTTAACATCA AAAGCGTGCA GTCACAAGGT 
TTTAAGCTGA ATGTATGGGA CATTGGCGGG CAGAGGAAAA TCAGACCATA CTGGAGAAGT 
TATTTTGAAA ATACTGATAT TCTCATCTAT GTAATTGACA GTGCCGACAG AAAGAGATTT 
GAAGAGACGG GTCAGGAACT AACGGAATTA CTGGAGGAAG AAAAGCTGAG TTGTGTGCCC 
GTGCTCATCT TTGCTAACAA GCAGGACCTG CTCACGGCAG CCCCAGCCTC CGAGATCGCA 
GAAGGGCTAA ACCTCCACAC CATCCGGGAC CGCGTCTGGC AGATCCAGTC CTGTTCAGCG 
CTCACAGGCG AGGGCGTCCA GGATGGCATG AACTGGGTCT GCAAGAATGT CAACGCAAAG 
AAGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).
The Journal of biological chemistry292(26)11091-11108(2017 06)
Ivanova AA,Caspary T,Seyfried NT,Duong DM,West AB,Liu Z,Kahn RA

ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment.
Human molecular genetics25(10)2031-2044(2016 05)
Wright ZC,Singh RK,Alpino R,Goldberg AF,Sokolov M,Ramamurthy V

PDE6?-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.
Nature communications711366(2016 Apr)
Fansa EK,K?sling SK,Zent E,Wittinghofer A,Ismail S

Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.
The Journal of biological chemistry291(13)7142-55(2016 Mar)
Hanke-Gogokhia C,Wu Z,Gerstner CD,Frederick JM,Zhang H,Baehr W

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Arl3 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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