Arl6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arl6
Entrez Gene ID	56297
Full Name	ADP-ribosylation factor-like 6
Synonyms	1110018H24Rik,2210411E14Rik,BBS3
General protein information	Preferred Names ADP-ribosylation factor-like 6 Names ADP-ribosylation factor-like protein 6 ADP-ribosylation-like 6 ADP-ribosylation-like factor homolog ARL6
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 16 Map Location: 16\|16 C1.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_019665.3	NP_062639.3	ADP-ribosylation factor-like protein 6 isoform 1
NM_001347244.1	NP_001334173.1	ADP-ribosylation factor-like protein 6 isoform 2

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CG7735	NP_611421.1
Caenorhabditis elegans (roundworm)	arl-6	NP_497993.1
Homo sapiens (human)	ARL6	NP_001265222.1
Canis lupus familiaris (dog)	ARL6	XP_005639411.1
Pan troglodytes (chimpanzee)	ARL6	XP_001139103.1
	ARL6	XP_001085821.1
Bos taurus (cattle)	ARL6	NP_001069250.1
Rattus norvegicus (Norway rat)	Arl6	NP_001102312.1
Danio rerio (zebrafish)	arl6	NP_001008733.1
Mus musculus (house mouse)	Arl6	NP_062639.3
Xenopus tropicalis (tropical clawed frog)	arl6	XP_002931823.2

Gene Ontology
Bibliography

Related articles in PubMed

Bardet-Biedl syndrome 3 regulates the development of cranial base midline structures.
Kawasaki M, Izu Y, Hayata T, Ideno H, Nifuji A, Sheffield VC, Ezura Y, Noda M
Bone101179-190(2017 Aug)

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA
Developmental biology406(1)92-103(2015 Oct)

The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
Liew GM, Ye F, Nager AR, Murphy JP, Lee JS, Aguiar M, Breslow DK, Gygi SP, Nachury MV
Developmental cell31(3)265-78(2014 Nov)

Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein.
Su X, Driscoll K, Yao G, Raed A, Wu M, Beales PL, Zhou J
Human molecular genetics23(20)5441-51(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IFT27 prevents aggregation of nucleotide-free ARL6 in solution
Title: The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

Results show that BBS1 and BBS3 regulates the ciliary traficking of PC1.
Title: Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein.

Bbs3 knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes
Title: Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes.

These data demonstrate that the BBS3L transcript is required for proper retinal function and organization.
Title: Identification and functional analysis of the vision-specific BBS3 (ARL6) long isoform.

ARL6 was expressed in the neural plate and probably in the somites
Title: Expression of ADP-ribosylation factor (ARF)-like protein 6 during mouse embryonic development.

The following Arl6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arl6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu11287	NM_019665.3 Latest version!	Mus musculus ADP-ribosylation factor-like 6 (Arl6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu52309	NM_001347244.1 Latest version!	Mus musculus ADP-ribosylation factor-like 6 (Arl6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arl6 ( NM_019665.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062639.3 Mus musculus ADP-ribosylation factor-like 6 (Arl6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu11287
Clone ID Related Accession (Same CDS sequence)	NM_019665.3
Accession Version	NM_019665.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY279441.1, AK160666.1 and CO040545.1. On May 17, 2008 this sequence version replaced NM_019665.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660811.3797.1, AK003778.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTTGC TGGACAGACT TTCAGGTTTG CTTGGCCTGA AGAAGAAGGA GGTTCATGTT 
CTGTGCCTGG GGCTGGATAA CAGTGGGAAA ACCACAATCA TTAACAAGCT GAAGCCTTCC 
AACGCTCAAT CTCAAGATAT AGTTCCAACC ATAGGATTTA GCATAGAGAA ATTCAAGTCC 
TCCAGTTTGT CTTTTACAGT GTTTGACATG TCAGGTCAAG GAAGGTACAG GAATCTCTGG 
GAACACTATT ATAAAGATGG ACAAGCCATT ATTTTTGTCA TTGATAGTAG TGATAAGTTA 
AGAATGGTTG TGGCCAAAGA AGAGCTTGAT ACCCTTCTGA ATCACCCAGA TATTAAGCAC 
CGTCGAATTC CAATCTTGTT CTTTGCAAAC AAAATGGACC TTAGAGACTC AGTGACCTCT 
GTGAAAGTGT CTCAGTTGCT GTGCTTAGAG AGCATTAAAG ACAAGCCGTG GCATATTTGT 
GCTAGTGACG CCATCAAAGG AGAAGGCCTG CAGGAAGGCG TGGACTGGCT CCAAGATCAG 
ATCCAAGCTG TGAAGACGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062639.3
CDS	438..998
Translation	MGLLDRLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQDQIQAVKT

Target ORF information:

RefSeq Version	NM_019665.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 6 (Arl6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019665.3

ORF Insert Sequence:

ATGGGCTTGC TGGACAGACT TTCAGGTTTG CTTGGCCTGA AGAAGAAGGA GGTTCATGTT 
CTGTGCCTGG GGCTGGATAA CAGTGGGAAA ACCACAATCA TTAACAAGCT GAAGCCTTCC 
AACGCTCAAT CTCAAGATAT AGTTCCAACC ATAGGATTTA GCATAGAGAA ATTCAAGTCC 
TCCAGTTTGT CTTTTACAGT GTTTGACATG TCAGGTCAAG GAAGGTACAG GAATCTCTGG 
GAACACTATT ATAAAGATGG ACAAGCCATT ATTTTTGTCA TTGATAGTAG TGATAAGTTA 
AGAATGGTTG TGGCCAAAGA AGAGCTTGAT ACCCTTCTGA ATCACCCAGA TATTAAGCAC 
CGTCGAATTC CAATCTTGTT CTTTGCAAAC AAAATGGACC TTAGAGACTC AGTGACCTCT 
GTGAAAGTGT CTCAGTTGCT GTGCTTAGAG AGCATTAAAG ACAAGCCGTG GCATATTTGT 
GCTAGTGACG CCATCAAAGG AGAAGGCCTG CAGGAAGGCG TGGACTGGCT CCAAGATCAG 
ATCCAAGCTG TGAAGACGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Arl6 ( NM_001347244.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334173.1 Mus musculus ADP-ribosylation factor-like 6 (Arl6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu52309
Clone ID Related Accession (Same CDS sequence)	NM_001347244.1
Accession Version	NM_001347244.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC154473.2, AK158832.1 and AK003778.1. On Nov 19, 2016 this sequence version replaced XM_006522398.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK158832.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTTGC TGGACAGACT TTCAGGTTTG CTTGGCCTGA AGAAGAAGGA GGTTCATGTT 
CTGTGCCTGG GGCTGGATAA CAGTGGGAAA ACCACAATCA TTAACAAGCT GAAGCCTTCC 
AACGCTCAAT CTCAAGATAT AGTTCCAACC ATAGGATTTA GCATAGAGAA ATTCAAGTCC 
TCCAGTTTGT CTTTTACAGT GTTTGACATG TCAGGTCAAG GAAGGTACAG GAATCTCTGG 
GAACACTATT ATAAAGATGG ACAAGCCATT ATTTTTGTCA TTGATAGTAG TGATAAGTTA 
AGAATGGTTG TGGCCAAAGA AGAGCTTGAT ACCCTTCTGA ATCACCCAGA TATTAAGCAC 
CGTCGAATTC CAATCTTGTT CTTTGCAAAC AAAATGGACC TTAGAGACTC AGTGACCTCT 
GTGAAAGTGT CTCAGTTGCT GTGCTTAGAG AGCATTAAAG ACAAGCCGTG GCATATTTGT 
GCTAGTGACG CCATCAAAGG AGAAGGCCTG CAGGAAGGCG TGGACTGGCT CCAAGAAAAA 
ACAGTACAAT CAGATCCAAG CTGTGAAGAC GTGAAGAGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334173.1
CDS	508..1089
Translation	MGLLDRLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQEKTVQSDPSCEDVKR

Target ORF information:

RefSeq Version	NM_001347244.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 6 (Arl6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347244.1

ORF Insert Sequence:

ATGGGCTTGC TGGACAGACT TTCAGGTTTG CTTGGCCTGA AGAAGAAGGA GGTTCATGTT 
CTGTGCCTGG GGCTGGATAA CAGTGGGAAA ACCACAATCA TTAACAAGCT GAAGCCTTCC 
AACGCTCAAT CTCAAGATAT AGTTCCAACC ATAGGATTTA GCATAGAGAA ATTCAAGTCC 
TCCAGTTTGT CTTTTACAGT GTTTGACATG TCAGGTCAAG GAAGGTACAG GAATCTCTGG 
GAACACTATT ATAAAGATGG ACAAGCCATT ATTTTTGTCA TTGATAGTAG TGATAAGTTA 
AGAATGGTTG TGGCCAAAGA AGAGCTTGAT ACCCTTCTGA ATCACCCAGA TATTAAGCAC 
CGTCGAATTC CAATCTTGTT CTTTGCAAAC AAAATGGACC TTAGAGACTC AGTGACCTCT 
GTGAAAGTGT CTCAGTTGCT GTGCTTAGAG AGCATTAAAG ACAAGCCGTG GCATATTTGT 
GCTAGTGACG CCATCAAAGG AGAAGGCCTG CAGGAAGGCG TGGACTGGCT CCAAGAAAAA 
ACAGTACAAT CAGATCCAAG CTGTGAAGAC GTGAAGAGAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bardet-Biedl syndrome 3 regulates the development of cranial base midline structures.
Bone101179-190(2017 Aug)
Kawasaki M,Izu Y,Hayata T,Ideno H,Nifuji A,Sheffield VC,Ezura Y,Noda M

Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Developmental biology406(1)92-103(2015 Oct)
Lewandowski JP,Du F,Zhang S,Powell MB,Falkenstein KN,Ji H,Vokes SA

The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
Developmental cell31(3)265-78(2014 Nov)
Liew GM,Ye F,Nager AR,Murphy JP,Lee JS,Aguiar M,Breslow DK,Gygi SP,Nachury MV

Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein.
Human molecular genetics23(20)5441-51(2014 Oct)
Su X,Driscoll K,Yao G,Raed A,Wu M,Beales PL,Zhou J

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Arl6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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