Patz1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Patz1
Entrez Gene ID	56218
Full Name	POZ (BTB) and AT hook containing zinc finger 1
Synonyms	8430401L15Rik,AI447519,Mazr,Patz,Zfp278
General protein information	Preferred Names POZ (BTB) and AT hook containing zinc finger 1 Names POZ-, AT hook-, and zinc finger-containing protein 1 POZ-AT hook-zinc finger protein transcription factor (MAZ-related) MAZR zinc finger protein 278
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_019574.3	NP_062520.1	POZ-, AT hook-, and zinc finger-containing protein 1 isoform 1
NM_001253690.1	NP_001240619.1	POZ-, AT hook-, and zinc finger-containing protein 1 isoform 2
NM_001253691.1	NP_001240620.1	POZ-, AT hook-, and zinc finger-containing protein 1 isoform 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Patz1	NP_062520.1
Xenopus tropicalis (tropical clawed frog)	patz1	XP_004910654.1
Pan troglodytes (chimpanzee)	PATZ1	XP_525568.3
Gallus gallus (chicken)	PATZ1	XP_004934428.1
Danio rerio (zebrafish)	patz1	XP_688779.3
Homo sapiens (human)	PATZ1	NP_055138.2
Bos taurus (cattle)	PATZ1	NP_001178126.1
Rattus norvegicus (Norway rat)	Patz1	NP_001100701.1
Canis lupus familiaris (dog)	PATZ1	XP_003433451.1

Gene Ontology
Bibliography

Related articles in PubMed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstr?m E, Pachnis V, Marklund U
Gastroenterology(2017 Oct)

miR-24 suppression of POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) protects endothelial cell from diabetic damage.
Cui YX, Hua YZ, Wang N, Chen X, Wang F, Liu JY, Wang LL, Yan CY, Ma YG, Cao YH, Zhang XH
Biochemical and biophysical research communications480(4)682-689(2016 11)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Hyperglycemia-induced PATZ1 negatively modulates endothelial vasculogenesis via repression of FABP4 signaling.
Chen RA, Sun XM, Yan CY, Liu L, Hao MW, Liu Q, Jiao XY, Liang YM
Biochemical and biophysical research communications477(4)548-555(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Together, these results suggest a novel mechanism regulating endothelial PATZ1 expression based on the down-regulation of miR-24 expression caused by hyperglycemia. Interfering with PATZ1 expression via miRNAs or miRNA mimics could potentially represent a new way to target endothelial PATZ1-dependent signaling of vascular dysfunction in diabetes.
Title: miR-24 suppression of POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) protects endothelial cell from diabetic damage.

endothelial PATZ1 thus potently inhibits endothelial function and angiogenesis via inhibition of FABP4 expression, and abnormal induction of endothelial PATZ1 may contribute to multiple aspects of vascular dysfunction in diabetes
Title: Hyperglycemia-induced PATZ1 negatively modulates endothelial vasculogenesis via repression of FABP4 signaling.

the repression of ThPOK during CD8 lineage differentiation is mediated by the synergistic activity of the transcription factor MAZR and Runx/CBFbeta complexes.
Title: MAZR and Runx Factors Synergistically Repress ThPOK during CD8+ T Cell Lineage Development.

Results show that PATZ1 binds to p53 and inhibits p53-dependent transcription activation.
Title: PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.

The data support a PATZ1 tumour-suppressive function based on its ability to enhance p53-dependent transcription and apoptosis.
Title: PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context.

The following Patz1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Patz1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05518	NM_001253690.1 Latest version!	Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu05519	NM_001253691.1 Latest version!	Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu11216	NM_019574.3 Latest version!	Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$377.30 $539.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Patz1 ( NM_001253690.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001240619.1 Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu05518
Clone ID Related Accession (Same CDS sequence)	NM_001253690.1
Accession Version	NM_001253690.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1614bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Mus musculus(house mouse)
Product	POZ-, AT hook-, and zinc finger-containing protein 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671968.17 and BC043035.1. Transcript Variant: This variant (4) includes an additional exon that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (2) has a distinct and shorter C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660811.242085.1, BF141996.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGGG TCAACGACGC TTCTTGCGGT CCGTCGGGCT GCTACACCTA CCAGGTGAGC 
AGACACAGTA CGGAGATGCT GCACAACCTG AACCAACAAC GCAAAAACGG CGGGCGCTTT 
TGCGACGTGC TCCTACGAGT AGGCGACGAG AGCTTCCCAG CGCACCGCGC CGTACTGGCT 
GCCTGCAGCG AGTACTTTGA GTCTGTGTTC AGCGCCCAGT TAGGCGACGG CGGAGCTGCA 
GATGGTGGTC CTGCTGATGT GGGAGGCGCG GCGGCGGCTC CAGGCGGCGG AGCTGGAGGC 
AGCCGCGAAC TGGAGATGCA CACCATCAGT TCCAAAGTGT TCGGAGACAT CCTGGACTTC 
GCTTATACGT CCCGAATCGT TGTGCGCCTA GAGAGCTTCC CCGAGCTCAT GACGGCCGCC 
AAGTTCCTGC TGATGAGGTC GGTCATCGAG ATCTGCCAGG AAGTAATCAA ACAGTCCAAC 
GTGCAGATCC TCGTGCCCCC TGCCCGGGCT GATATCATGC TCTTTCGCCC ACCTGGGACT 
TCTGACTTGG GCTTCCCTTT GGACATGACC AACGGGGCAG CCATGGCAGC CAACAGTAAC 
GGTATTGCTG GCAGTATGCA GCCCGAGGAG GAGGCTGCCA GGGCCACAGG TGCTGCTATT 
GCGGGCCAAG CTTCTCTGCC TGTGTTACCC GGGGTGGACA GATTGCCCAT GGTGGCTGGA 
CCCCTATCCC CCCAACTACT GACTTCTCCG TTCCCTAATG TGGCATCCAG TGCACCTCCA 
CTAACTAGCA AGCGAGGCCG GGGACGCCCC AGGAAGGCCA ACCTGCTGGA CTCCATGTTT 
GGGTCTCCAG GGGGCTTGAG GGAAGCAGGC ATCCTTCCAT GTGGCCTGTG CGGGAAGGTG 
TTCACTGACG CCAACCGGCT CCGGCAACAT GAGGCCCAGC ACGGCGTCAC AAGCCTCCAG 
TTGGGCTATA TCGATCTTCC TCCTCCAAGG CTGGGTGAGA ATGGGTTACC CATCTCCGAG 
GACCCCGATG GCCCCAGAAA AAGGAGCCGG ACCAGGAAGC AAGTGGCTTG TGAGATCTGT 
GGCAAGATCT TTCGTGACGT ATACCATCTC AACCGGCATA AGCTTTCCCA CTCGGGGGAG 
AAGCCGTACT CGTGCCCGGT GTGTGGTCTG CGGTTCAAGA GAAAAGACCG AATGTCGTAC 
CATGTGAGGT CCCATGATGG GTCAGTGGGC AAACCGTACA TCTGCCAGAG CTGTGGGAAA 
GGTTTCTCCA GGCCAGATCA CTTGAATGGA CATATCAAGC AGGTGCACAC TTCTGAGCGA 
CCTCACAAGT GTCAGACCTG CAATGCCTCC TTTGCGACTC GAGACCGCCT GCGCTCCCAC 
CTGGCCTGTC ATGAAGACAA GGTGCCCTGC CAGGTGTGTG GAAAGTACTT GCGGGCCGCA 
TACATGGCAG ACCACCTGAA GAAGCACAGT GAGGGGCCCA GCAACTTCTG TAGCATCTGT 
AACCGAGGTC TCCAGGCACC AGGAACCCAT CCTGAATGGG GGAGCAGCGT TCCACTGCGC 
CAGGACCTAT GGCAACAAAG AAGGCCAGAA ATGCTCACAT CAGGATCTGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001240619.1
CDS	158..1771
Translation	MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTSKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGLQAPGTHPEWGSSVPLRQDLWQQRRPEMLTSGSD

Target ORF information:

RefSeq Version	NM_001253690.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001253690.1

ORF Insert Sequence:

ATGGAGCGGG TCAACGACGC TTCTTGCGGT CCGTCGGGCT GCTACACCTA CCAGGTGAGC 
AGACACAGTA CGGAGATGCT GCACAACCTG AACCAACAAC GCAAAAACGG CGGGCGCTTT 
TGCGACGTGC TCCTACGAGT AGGCGACGAG AGCTTCCCAG CGCACCGCGC CGTACTGGCT 
GCCTGCAGCG AGTACTTTGA GTCTGTGTTC AGCGCCCAGT TAGGCGACGG CGGAGCTGCA 
GATGGTGGTC CTGCTGATGT GGGAGGCGCG GCGGCGGCTC CAGGCGGCGG AGCTGGAGGC 
AGCCGCGAAC TGGAGATGCA CACCATCAGT TCCAAAGTGT TCGGAGACAT CCTGGACTTC 
GCTTATACGT CCCGAATCGT TGTGCGCCTA GAGAGCTTCC CCGAGCTCAT GACGGCCGCC 
AAGTTCCTGC TGATGAGGTC GGTCATCGAG ATCTGCCAGG AAGTAATCAA ACAGTCCAAC 
GTGCAGATCC TCGTGCCCCC TGCCCGGGCT GATATCATGC TCTTTCGCCC ACCTGGGACT 
TCTGACTTGG GCTTCCCTTT GGACATGACC AACGGGGCAG CCATGGCAGC CAACAGTAAC 
GGTATTGCTG GCAGTATGCA GCCCGAGGAG GAGGCTGCCA GGGCCACAGG TGCTGCTATT 
GCGGGCCAAG CTTCTCTGCC TGTGTTACCC GGGGTGGACA GATTGCCCAT GGTGGCTGGA 
CCCCTATCCC CCCAACTACT GACTTCTCCG TTCCCTAATG TGGCATCCAG TGCACCTCCA 
CTAACTAGCA AGCGAGGCCG GGGACGCCCC AGGAAGGCCA ACCTGCTGGA CTCCATGTTT 
GGGTCTCCAG GGGGCTTGAG GGAAGCAGGC ATCCTTCCAT GTGGCCTGTG CGGGAAGGTG 
TTCACTGACG CCAACCGGCT CCGGCAACAT GAGGCCCAGC ACGGCGTCAC AAGCCTCCAG 
TTGGGCTATA TCGATCTTCC TCCTCCAAGG CTGGGTGAGA ATGGGTTACC CATCTCCGAG 
GACCCCGATG GCCCCAGAAA AAGGAGCCGG ACCAGGAAGC AAGTGGCTTG TGAGATCTGT 
GGCAAGATCT TTCGTGACGT ATACCATCTC AACCGGCATA AGCTTTCCCA CTCGGGGGAG 
AAGCCGTACT CGTGCCCGGT GTGTGGTCTG CGGTTCAAGA GAAAAGACCG AATGTCGTAC 
CATGTGAGGT CCCATGATGG GTCAGTGGGC AAACCGTACA TCTGCCAGAG CTGTGGGAAA 
GGTTTCTCCA GGCCAGATCA CTTGAATGGA CATATCAAGC AGGTGCACAC TTCTGAGCGA 
CCTCACAAGT GTCAGACCTG CAATGCCTCC TTTGCGACTC GAGACCGCCT GCGCTCCCAC 
CTGGCCTGTC ATGAAGACAA GGTGCCCTGC CAGGTGTGTG GAAAGTACTT GCGGGCCGCA 
TACATGGCAG ACCACCTGAA GAAGCACAGT GAGGGGCCCA GCAACTTCTG TAGCATCTGT 
AACCGAGGTC TCCAGGCACC AGGAACCCAT CCTGAATGGG GGAGCAGCGT TCCACTGCGC 
CAGGACCTAT GGCAACAAAG AAGGCCAGAA ATGCTCACAT CAGGATCTGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Patz1 ( NM_001253691.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001240620.1 Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu05519
Clone ID Related Accession (Same CDS sequence)	NM_001253691.1
Accession Version	NM_001253691.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Mus musculus(house mouse)
Product	POZ-, AT hook-, and zinc finger-containing protein 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671968.17, CA327687.1 and BC043035.1. Transcript Variant: This variant (5) includes an additional exon that causes a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (3) has a distinct and shorter C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ886184.1, CA327687.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCGGG TCAACGACGC TTCTTGCGGT CCGTCGGGCT GCTACACCTA CCAGGTGAGC 
AGACACAGTA CGGAGATGCT GCACAACCTG AACCAACAAC GCAAAAACGG CGGGCGCTTT 
TGCGACGTGC TCCTACGAGT AGGCGACGAG AGCTTCCCAG CGCACCGCGC CGTACTGGCT 
GCCTGCAGCG AGTACTTTGA GTCTGTGTTC AGCGCCCAGT TAGGCGACGG CGGAGCTGCA 
GATGGTGGTC CTGCTGATGT GGGAGGCGCG GCGGCGGCTC CAGGCGGCGG AGCTGGAGGC 
AGCCGCGAAC TGGAGATGCA CACCATCAGT TCCAAAGTGT TCGGAGACAT CCTGGACTTC 
GCTTATACGT CCCGAATCGT TGTGCGCCTA GAGAGCTTCC CCGAGCTCAT GACGGCCGCC 
AAGTTCCTGC TGATGAGGTC GGTCATCGAG ATCTGCCAGG AAGTAATCAA ACAGTCCAAC 
GTGCAGATCC TCGTGCCCCC TGCCCGGGCT GATATCATGC TCTTTCGCCC ACCTGGGACT 
TCTGACTTGG GCTTCCCTTT GGACATGACC AACGGGGCAG CCATGGCAGC CAACAGTAAC 
GGTATTGCTG GCAGTATGCA GCCCGAGGAG GAGGCTGCCA GGGCCACAGG TGCTGCTATT 
GCGGGCCAAG CTTCTCTGCC TGTGTTACCC GGGGTGGACA GATTGCCCAT GGTGGCTGGA 
CCCCTATCCC CCCAACTACT GACTTCTCCG TTCCCTAATG TGGCATCCAG TGCACCTCCA 
CTAACTAGCA AGCGAGGCCG GGGACGCCCC AGGAAGGCCA ACCTGCTGGA CTCCATGTTT 
GGGTCTCCAG GGGGCTTGAG GGAAGCAGGC ATCCTTCCAT GTGGCCTGTG CGGGAAGGTG 
TTCACTGACG CCAACCGGCT CCGGCAACAT GAGGCCCAGC ACGGCGTCAC AAGCCTCCAG 
TTGGGCTATA TCGATCTTCC TCCTCCAAGG CTGGGTGAGA ATGGGTTACC CATCTCCGAG 
GACCCCGATG GCCCCAGAAA AAGGAGCCGG ACCAGGAAGC AAGTGGCTTG TGAGATCTGT 
GGCAAGATCT TTCGTGACGT ATACCATCTC AACCGGCATA AGCTTTCCCA CTCGGGGGAG 
AAGCCGTACT CGTGCCCGGT GTGTGGTCTG CGGTTCAAGA GAAAAGACCG AATGTCGTAC 
CATGTGAGGT CCCATGATGG GTCAGTGGGC AAACCGTACA TCTGCCAGAG CTGTGGGAAA 
GGTTTCTCCA GGCCAGATCA CTTGAATGGA CATATCAAGC AGGTGCACAC TTCTGAGCGA 
CCTCACAAGT GTCAGGTGTG GGTTGGGAGC AGCAGCGGCC TGCCGCCCCT GGAACCTCTT 
CCTAGCGACC TGCCATCATG GGACTTTGCC CAGCCTGCTT TGTGGAGACC TGCAATGCCT 
CCTTTGCGAC TCGAGACCGC CTGCGCTCCC ACCTGGCCTG TCATGAAGAC AAGGTGCCCT 
GCCAGGTGTG TGGAAAGTAC TTGCGGGCCG CATACATGGC AGACCACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001240620.1
CDS	158..1708
Translation	MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTSKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQVWVGSSSGLPPLEPLPSDLPSWDFAQPALWRPAMPPLRLETACAPTWPVMKTRCPARCVESTCGPHTWQTT

Target ORF information:

RefSeq Version	NM_001253691.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001253691.1

ORF Insert Sequence:

ATGGAGCGGG TCAACGACGC TTCTTGCGGT CCGTCGGGCT GCTACACCTA CCAGGTGAGC 
AGACACAGTA CGGAGATGCT GCACAACCTG AACCAACAAC GCAAAAACGG CGGGCGCTTT 
TGCGACGTGC TCCTACGAGT AGGCGACGAG AGCTTCCCAG CGCACCGCGC CGTACTGGCT 
GCCTGCAGCG AGTACTTTGA GTCTGTGTTC AGCGCCCAGT TAGGCGACGG CGGAGCTGCA 
GATGGTGGTC CTGCTGATGT GGGAGGCGCG GCGGCGGCTC CAGGCGGCGG AGCTGGAGGC 
AGCCGCGAAC TGGAGATGCA CACCATCAGT TCCAAAGTGT TCGGAGACAT CCTGGACTTC 
GCTTATACGT CCCGAATCGT TGTGCGCCTA GAGAGCTTCC CCGAGCTCAT GACGGCCGCC 
AAGTTCCTGC TGATGAGGTC GGTCATCGAG ATCTGCCAGG AAGTAATCAA ACAGTCCAAC 
GTGCAGATCC TCGTGCCCCC TGCCCGGGCT GATATCATGC TCTTTCGCCC ACCTGGGACT 
TCTGACTTGG GCTTCCCTTT GGACATGACC AACGGGGCAG CCATGGCAGC CAACAGTAAC 
GGTATTGCTG GCAGTATGCA GCCCGAGGAG GAGGCTGCCA GGGCCACAGG TGCTGCTATT 
GCGGGCCAAG CTTCTCTGCC TGTGTTACCC GGGGTGGACA GATTGCCCAT GGTGGCTGGA 
CCCCTATCCC CCCAACTACT GACTTCTCCG TTCCCTAATG TGGCATCCAG TGCACCTCCA 
CTAACTAGCA AGCGAGGCCG GGGACGCCCC AGGAAGGCCA ACCTGCTGGA CTCCATGTTT 
GGGTCTCCAG GGGGCTTGAG GGAAGCAGGC ATCCTTCCAT GTGGCCTGTG CGGGAAGGTG 
TTCACTGACG CCAACCGGCT CCGGCAACAT GAGGCCCAGC ACGGCGTCAC AAGCCTCCAG 
TTGGGCTATA TCGATCTTCC TCCTCCAAGG CTGGGTGAGA ATGGGTTACC CATCTCCGAG 
GACCCCGATG GCCCCAGAAA AAGGAGCCGG ACCAGGAAGC AAGTGGCTTG TGAGATCTGT 
GGCAAGATCT TTCGTGACGT ATACCATCTC AACCGGCATA AGCTTTCCCA CTCGGGGGAG 
AAGCCGTACT CGTGCCCGGT GTGTGGTCTG CGGTTCAAGA GAAAAGACCG AATGTCGTAC 
CATGTGAGGT CCCATGATGG GTCAGTGGGC AAACCGTACA TCTGCCAGAG CTGTGGGAAA 
GGTTTCTCCA GGCCAGATCA CTTGAATGGA CATATCAAGC AGGTGCACAC TTCTGAGCGA 
CCTCACAAGT GTCAGGTGTG GGTTGGGAGC AGCAGCGGCC TGCCGCCCCT GGAACCTCTT 
CCTAGCGACC TGCCATCATG GGACTTTGCC CAGCCTGCTT TGTGGAGACC TGCAATGCCT 
CCTTTGCGAC TCGAGACCGC CTGCGCTCCC ACCTGGCCTG TCATGAAGAC AAGGTGCCCT 
GCCAGGTGTG TGGAAAGTAC TTGCGGGCCG CATACATGGC AGACCACCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Patz1 ( NM_019574.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062520.1 Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu11216
Clone ID Related Accession (Same CDS sequence)	NM_019574.3
Accession Version	NM_019574.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Mus musculus(house mouse)
Product	POZ-, AT hook-, and zinc finger-containing protein 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL671968.17. On Sep 3, 2011 this sequence version replaced NM_019574.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB029397.1, SRR1660817.2393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCGGG TCAACGACGC TTCTTGCGGT CCGTCGGGCT GCTACACCTA CCAGGTGAGC 
AGACACAGTA CGGAGATGCT GCACAACCTG AACCAACAAC GCAAAAACGG CGGGCGCTTT 
TGCGACGTGC TCCTACGAGT AGGCGACGAG AGCTTCCCAG CGCACCGCGC CGTACTGGCT 
GCCTGCAGCG AGTACTTTGA GTCTGTGTTC AGCGCCCAGT TAGGCGACGG CGGAGCTGCA 
GATGGTGGTC CTGCTGATGT GGGAGGCGCG GCGGCGGCTC CAGGCGGCGG AGCTGGAGGC 
AGCCGCGAAC TGGAGATGCA CACCATCAGT TCCAAAGTGT TCGGAGACAT CCTGGACTTC 
GCTTATACGT CCCGAATCGT TGTGCGCCTA GAGAGCTTCC CCGAGCTCAT GACGGCCGCC 
AAGTTCCTGC TGATGAGGTC GGTCATCGAG ATCTGCCAGG AAGTAATCAA ACAGTCCAAC 
GTGCAGATCC TCGTGCCCCC TGCCCGGGCT GATATCATGC TCTTTCGCCC ACCTGGGACT 
TCTGACTTGG GCTTCCCTTT GGACATGACC AACGGGGCAG CCATGGCAGC CAACAGTAAC 
GGTATTGCTG GCAGTATGCA GCCCGAGGAG GAGGCTGCCA GGGCCACAGG TGCTGCTATT 
GCGGGCCAAG CTTCTCTGCC TGTGTTACCC GGGGTGGACA GATTGCCCAT GGTGGCTGGA 
CCCCTATCCC CCCAACTACT GACTTCTCCG TTCCCTAATG TGGCATCCAG TGCACCTCCA 
CTAACTAGCA AGCGAGGCCG GGGACGCCCC AGGAAGGCCA ACCTGCTGGA CTCCATGTTT 
GGGTCTCCAG GGGGCTTGAG GGAAGCAGGC ATCCTTCCAT GTGGCCTGTG CGGGAAGGTG 
TTCACTGACG CCAACCGGCT CCGGCAACAT GAGGCCCAGC ACGGCGTCAC AAGCCTCCAG 
TTGGGCTATA TCGATCTTCC TCCTCCAAGG CTGGGTGAGA ATGGGTTACC CATCTCCGAG 
GACCCCGATG GCCCCAGAAA AAGGAGCCGG ACCAGGAAGC AAGTGGCTTG TGAGATCTGT 
GGCAAGATCT TTCGTGACGT ATACCATCTC AACCGGCATA AGCTTTCCCA CTCGGGGGAG 
AAGCCGTACT CGTGCCCGGT GTGTGGTCTG CGGTTCAAGA GAAAAGACCG AATGTCGTAC 
CATGTGAGGT CCCATGATGG GTCAGTGGGC AAACCGTACA TCTGCCAGAG CTGTGGGAAA 
GGTTTCTCCA GGCCAGATCA CTTGAATGGA CATATCAAGC AGGTGCACAC TTCTGAGCGA 
CCTCACAAGT GTCAGACCTG CAATGCCTCC TTTGCGACTC GAGACCGCCT GCGCTCCCAC 
CTGGCCTGTC ATGAAGACAA GGTGCCCTGC CAGGTGTGTG GAAAGTACTT GCGGGCCGCA 
TACATGGCAG ACCACCTGAA GAAGCACAGT GAGGGGCCCA GCAACTTCTG TAGCATCTGT 
AACCGAGAAG GCCAGAAATG CTCACATCAG GATCTGATTG AGAGCTCCGA CTCCTACGGT 
GACCTCTCCG ACGCCAGCGA CCTGAAGACG CCAGAGAAAC AGAGTGCCAA CGGCTCCTTC 
TCCTGCGACG TGGCAGTCCC TAAAAACAAA ATGGAGTCTG ACGGGGAGAA GAAGTACCCA 
TGCCCTGAAT GTGGGAGCTT CTTCCGTTCT AAGTCCTACT TGAACAAACA CATCCAGAAG 
GTGCATGTCC GTGCCCTTGG GGGTCCCTTG GGGGACCTGG GCCCTGCCCT TGGTTCACCT 
TTCTCTCCCC AGCAGAACAT GTCTCTTCTT GAGTCCTTTG GATTTCAGAT TGTTCAGTCA 
GCGTTTGCAT CATCTTTAGT GGATCCTGAG GTGGACCAGC AGCCCATGGG GCCTGAAGGG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062520.1
CDS	158..2083
Translation	MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTSKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNREGQKCSHQDLIESSDSYGDLSDASDLKTPEKQSANGSFSCDVAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK

Target ORF information:

RefSeq Version	NM_019574.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus POZ (BTB) and AT hook containing zinc finger 1 (Patz1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019574.3

ORF Insert Sequence:

ATGGAGCGGG TCAACGACGC TTCTTGCGGT CCGTCGGGCT GCTACACCTA CCAGGTGAGC 
AGACACAGTA CGGAGATGCT GCACAACCTG AACCAACAAC GCAAAAACGG CGGGCGCTTT 
TGCGACGTGC TCCTACGAGT AGGCGACGAG AGCTTCCCAG CGCACCGCGC CGTACTGGCT 
GCCTGCAGCG AGTACTTTGA GTCTGTGTTC AGCGCCCAGT TAGGCGACGG CGGAGCTGCA 
GATGGTGGTC CTGCTGATGT GGGAGGCGCG GCGGCGGCTC CAGGCGGCGG AGCTGGAGGC 
AGCCGCGAAC TGGAGATGCA CACCATCAGT TCCAAAGTGT TCGGAGACAT CCTGGACTTC 
GCTTATACGT CCCGAATCGT TGTGCGCCTA GAGAGCTTCC CCGAGCTCAT GACGGCCGCC 
AAGTTCCTGC TGATGAGGTC GGTCATCGAG ATCTGCCAGG AAGTAATCAA ACAGTCCAAC 
GTGCAGATCC TCGTGCCCCC TGCCCGGGCT GATATCATGC TCTTTCGCCC ACCTGGGACT 
TCTGACTTGG GCTTCCCTTT GGACATGACC AACGGGGCAG CCATGGCAGC CAACAGTAAC 
GGTATTGCTG GCAGTATGCA GCCCGAGGAG GAGGCTGCCA GGGCCACAGG TGCTGCTATT 
GCGGGCCAAG CTTCTCTGCC TGTGTTACCC GGGGTGGACA GATTGCCCAT GGTGGCTGGA 
CCCCTATCCC CCCAACTACT GACTTCTCCG TTCCCTAATG TGGCATCCAG TGCACCTCCA 
CTAACTAGCA AGCGAGGCCG GGGACGCCCC AGGAAGGCCA ACCTGCTGGA CTCCATGTTT 
GGGTCTCCAG GGGGCTTGAG GGAAGCAGGC ATCCTTCCAT GTGGCCTGTG CGGGAAGGTG 
TTCACTGACG CCAACCGGCT CCGGCAACAT GAGGCCCAGC ACGGCGTCAC AAGCCTCCAG 
TTGGGCTATA TCGATCTTCC TCCTCCAAGG CTGGGTGAGA ATGGGTTACC CATCTCCGAG 
GACCCCGATG GCCCCAGAAA AAGGAGCCGG ACCAGGAAGC AAGTGGCTTG TGAGATCTGT 
GGCAAGATCT TTCGTGACGT ATACCATCTC AACCGGCATA AGCTTTCCCA CTCGGGGGAG 
AAGCCGTACT CGTGCCCGGT GTGTGGTCTG CGGTTCAAGA GAAAAGACCG AATGTCGTAC 
CATGTGAGGT CCCATGATGG GTCAGTGGGC AAACCGTACA TCTGCCAGAG CTGTGGGAAA 
GGTTTCTCCA GGCCAGATCA CTTGAATGGA CATATCAAGC AGGTGCACAC TTCTGAGCGA 
CCTCACAAGT GTCAGACCTG CAATGCCTCC TTTGCGACTC GAGACCGCCT GCGCTCCCAC 
CTGGCCTGTC ATGAAGACAA GGTGCCCTGC CAGGTGTGTG GAAAGTACTT GCGGGCCGCA 
TACATGGCAG ACCACCTGAA GAAGCACAGT GAGGGGCCCA GCAACTTCTG TAGCATCTGT 
AACCGAGAAG GCCAGAAATG CTCACATCAG GATCTGATTG AGAGCTCCGA CTCCTACGGT 
GACCTCTCCG ACGCCAGCGA CCTGAAGACG CCAGAGAAAC AGAGTGCCAA CGGCTCCTTC 
TCCTGCGACG TGGCAGTCCC TAAAAACAAA ATGGAGTCTG ACGGGGAGAA GAAGTACCCA 
TGCCCTGAAT GTGGGAGCTT CTTCCGTTCT AAGTCCTACT TGAACAAACA CATCCAGAAG 
GTGCATGTCC GTGCCCTTGG GGGTCCCTTG GGGGACCTGG GCCCTGCCCT TGGTTCACCT 
TTCTCTCCCC AGCAGAACAT GTCTCTTCTT GAGTCCTTTG GATTTCAGAT TGTTCAGTCA 
GCGTTTGCAT CATCTTTAGT GGATCCTGAG GTGGACCAGC AGCCCATGGG GCCTGAAGGG 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Gastroenterology(2017 Oct)
Memic F,Knoflach V,Morarach K,Sadler R,Laranjeira C,Hjerling-Leffler J,Sundstr?m E,Pachnis V,Marklund U

miR-24 suppression of POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) protects endothelial cell from diabetic damage.
Biochemical and biophysical research communications480(4)682-689(2016 11)
Cui YX,Hua YZ,Wang N,Chen X,Wang F,Liu JY,Wang LL,Yan CY,Ma YG,Cao YH,Zhang XH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Hyperglycemia-induced PATZ1 negatively modulates endothelial vasculogenesis via repression of FABP4 signaling.
Biochemical and biophysical research communications477(4)548-555(2016 09)
Chen RA,Sun XM,Yan CY,Liu L,Hao MW,Liu Q,Jiao XY,Liang YM

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Patz1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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