Nmu cDNA ORF clone, Mus musculus(house mouse)

Role of neuromedin U in accelerating of non-alcoholic steatohepatitis in mice.
Teranishi H, Hayashi M, Higa R, Mori K, Miyazawa T, Hino J, Amano Y, Tozawa R, Ida T, Hanada T, Miyazato M, Hanada R, Kangawa K, Nakao K
Peptides99134-141(2018 01)

Identification of neuromedin U precursor-related peptide and its possible role in the regulation of prolactin release.
Mori K, Ida T, Fudetani M, Mori M, Kaiya H, Hino J, Nakahara K, Murakami N, Miyazato M, Kangawa K
Scientific reports7(1)10468(2017 Sep)

The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.
Klose CSN, Mahlak?iv T, Moeller JB, Rankin LC, Flamar AL, Kabata H, Monticelli LA, Moriyama S, Putzel GG, Rakhilin N, Shen X, Kostenis E, K?nig GM, Senda T, Carpenter D, Farber DL, Artis D
Nature549(7671)282-286(2017 09)

Neuronal regulation of type 2 innate lymphoid cells via neuromedin U.
Cardoso V, Chesn? J, Ribeiro H, Garc?a-Cassani B, Carvalho T, Bouchery T, Shah K, Barbosa-Morais NL, Harris N, Veiga-Fernandes H
Nature549(7671)277-281(2017 09)

Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway.
Hanada R, Teranishi H, Pearson JT, Kurokawa M, Hosoda H, Fukushima N, Fukue Y, Serino R, Fujihara H, Ueta Y, Ikawa M, Okabe M, Murakami N, Shirai M, Yoshimatsu H, Kangawa K, Kojima M
Nature medicine10(10)1067-73(2004 Oct)

These results suggested that NMU can act directly on beta cells through NMUR1 in an autocrine or paracrine fashion to suppress insulin secretion. Collectively, our results highlight the crucial role of NMU in suppressing pancreatic insulin secretion, and may improve our understanding of glucose homeostasis.
Title: Neuromedin U suppresses glucose-stimulated insulin secretion in pancreatic ? cells.

These results suggest that NMU and NMS are involved in thermoregulation via the prostaglandin E2 and beta3 adrenergic receptors, but that endogenous NMS might play a more predominant role than NMU.
Title: Involvement of endogenous neuromedin U and neuromedin S in thermoregulation.

the anorectic effect of the lipidated NMU is partly mediated by a decrease in gastric emptying which is subject to tachyphylaxis after continuous dosing.
Title: Neuromedin U inhibits food intake partly by inhibiting gastric emptying.

Beta-adrenergic and cholinergic mechanisms are involved in the anxiolytic action of neuromedin-U.
Title: Anxiolytic action of neuromedin-U and neurotransmitters involved in mice.

Data show that neuromedin U (NMU)-deficient mice developed less severe arthritis than control mice.
Title: The neuropeptide neuromedin U promotes autoantibody-mediated arthritis.