Hpgds cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hpgds
Entrez Gene ID	54486
Full Name	hematopoietic prostaglandin D synthase
Synonyms	H-PGDS,Ptgds2
General protein information	Preferred Names hematopoietic prostaglandin D synthase Names hematopoietic prostaglandin D synthase GST class-sigma glutathione S-transferase glutathione-dependent PGD synthase glutathione-dependent PGD synthetase glutathione-requiring prostaglandin D synthase prostaglandin D2 synthase 2, hematopoietic prostaglandin-H2 D-isomerase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 C1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006506398.3	XP_006506461.1	hematopoietic prostaglandin D synthase isoform X1
XM_006506398.4	XP_006506461.1	hematopoietic prostaglandin D synthase isoform X1
NM_019455.4	NP_062328.3	hematopoietic prostaglandin D synthase

Pathways from BioSystems

Homologies

	HPGDS	XP_001102342.1
Canis lupus familiaris (dog)	HPGDS	NP_001186973.1
Gallus gallus (chicken)	HPGDS	NP_990342.1
Caenorhabditis elegans (roundworm)	gst-37	NP_503532.1
Caenorhabditis elegans (roundworm)	gst-8	NP_494884.1
Caenorhabditis elegans (roundworm)	gst-3	NP_501846.1
Caenorhabditis elegans (roundworm)	gst-20	NP_496858.1
Caenorhabditis elegans (roundworm)	gst-14	NP_496861.1
Caenorhabditis elegans (roundworm)	gst-16	NP_496863.1
Caenorhabditis elegans (roundworm)	gst-31	NP_497121.1
Caenorhabditis elegans (roundworm)	gst-17	NP_496865.1
Caenorhabditis elegans (roundworm)	gst-27	NP_497116.1
Caenorhabditis elegans (roundworm)	gst-21	NP_001256002.1
Xenopus tropicalis (tropical clawed frog)	hpgds	NP_001005090.1
Drosophila melanogaster (fruit fly)	GstS1	NP_001261040.1
Caenorhabditis elegans (roundworm)	gst-19	NP_496864.1
Caenorhabditis elegans (roundworm)	gst-29	NP_497118.1
Caenorhabditis elegans (roundworm)	gst-35	NP_741061.2
Caenorhabditis elegans (roundworm)	gst-22	NP_507095.1
Caenorhabditis elegans (roundworm)	gst-38	NP_506983.1
Rattus norvegicus (Norway rat)	Hpgds	NP_113832.1
Anopheles gambiae (African malaria mosquito)	GST_ANOGA	XP_311546.4
Caenorhabditis elegans (roundworm)	gst-5	NP_001254267.1
Caenorhabditis elegans (roundworm)	gst-4	NP_501848.1
Caenorhabditis elegans (roundworm)	gst-15	NP_496860.1
Caenorhabditis elegans (roundworm)	gst-39	NP_497119.1
Caenorhabditis elegans (roundworm)	gst-24	NP_496859.1
Pan troglodytes (chimpanzee)	HPGDS	XP_001163736.1
Bos taurus (cattle)	HPGDS	XP_005207797.1
Mus musculus (house mouse)	Hpgds	NP_062328.3
Caenorhabditis elegans (roundworm)	gst-9	NP_001022266.1
Caenorhabditis elegans (roundworm)	gst-6	NP_494882.2
Caenorhabditis elegans (roundworm)	gst-7	NP_494883.1
Caenorhabditis elegans (roundworm)	gst-28	NP_497117.1
Caenorhabditis elegans (roundworm)	gst-13	NP_495967.1
Caenorhabditis elegans (roundworm)	gst-32	NP_497123.2
Caenorhabditis elegans (roundworm)	gst-12	NP_496862.1
Caenorhabditis elegans (roundworm)	gst-34	NP_741060.2
Caenorhabditis elegans (roundworm)	gst-36	NP_509652.2
Homo sapiens (human)	HPGDS	NP_055300.1
Caenorhabditis elegans (roundworm)	gst-30	NP_494902.1
Caenorhabditis elegans (roundworm)	gst-2	NP_501847.1
Caenorhabditis elegans (roundworm)	gst-18	NP_496866.1
Caenorhabditis elegans (roundworm)	gst-26	NP_497115.1
Caenorhabditis elegans (roundworm)	gst-33	NP_503968.1
Caenorhabditis elegans (roundworm)	gst-11	NP_508625.1

Gene Ontology
Bibliography

Related articles in PubMed

PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.
Nakamura T, Maeda S, Horiguchi K, Maehara T, Aritake K, Choi BI, Iwakura Y, Urade Y, Murata T
Nature communications67514(2015 Jul)

Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination.
Trimarco A, Forese MG, Alfieri V, Lucente A, Brambilla P, Dina G, Pieragostino D, Sacchetta P, Urade Y, Boizet-Bonhoure B, Martinelli Boneschi F, Quattrini A, Taveggia C
Nature neuroscience17(12)1682-92(2014 Dec)

Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity.
Trivedi SG, Newson J, Rajakariar R, Jacques TS, Hannon R, Kanaoka Y, Eguchi N, Colville-Nash P, Gilroy DW
Proceedings of the National Academy of Sciences of the United States of America103(13)5179-84(2006 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).
Title: PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.

HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.
Title: Hematopoetic prostaglandin D synthase: an ESR1-dependent oviductal epithelial cell synthase.

Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9.
Title: Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein.

These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.
Title: Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury.

Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.
Title: Protective role of hematopoietic prostaglandin D synthase in transient focal cerebral ischemia in mice.

The following Hpgds gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hpgds cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10964	NM_019455.4 Latest version!	Mus musculus hematopoietic prostaglandin D synthase (Hpgds), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu37452	XM_006506398.4 Latest version!	Mus musculus hematopoietic prostaglandin D synthase (Hpgds), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu37452	XM_006506398.3	Mus musculus hematopoietic prostaglandin D synthase (Hpgds), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hpgds ( XM_006506398.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506461.1 Mus musculus hematopoietic prostaglandin D synthase (Hpgds), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37452
Clone ID Related Accession (Same CDS sequence)	XM_006506398.3 , XM_006506398.4
Accession Version	XM_006506398.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	hematopoietic prostaglandin D synthase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006506398.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTAACT ACAAACTGCT TTATTTTAAT ATGAGGGGAA GAGCCGAAAT TATTCGCTAC 
ATATTCGCTT ATTTGGACAT AAAGTATGAG GATCACAGAA TAGAACAAGC TGACTGGCCT 
AAAATCAAGC CAACTCTTCC ATTTGGCAAA ATCCCTGTTT TGGAGGTGGA AGGACTTACA 
ATCCACCAGA GCCTCGCAAT AGCAAGATAT TTGACCAAAA ACACAGATTT GGCTGGGAAG 
ACAGCGTTGG AGCAATGTCA AGCTGATGCA GTGGTGGACA CGCTGGATGA CTTCATGTCT 
CTCTTCCCAT GGGCAGAGAA AGATCAAGAT CTAAAAGAGC GGATGTTCAA TGAATTGCTC 
ACACATCAAG CACCTCGCCT TCTGAAAGAT TTGGACACAT ACTTAGGAGA CAAAGAGTGG 
TTTATAGGCA ATTATCAGGT AACCTGGGCA GACTTCTACT GGGATATCTG CAGCACCACA 
CTTTTGGTTT TAAAGCCTGG CTTGTTGGAT ATCTACCCCA AACTGGTGTC ATTACGGAAC 
AAAGTCCAAG CTATCCCTGC CATTTCTGCC TGGATACTAA AGAGGCCACA GACAAAACTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506461.1
CDS	353..955
Translation	MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQSLAIARYLTKNTDLAGKTALEQCQADAVVDTLDDFMSLFPWAEKDQDLKERMFNELLTHQAPRLLKDLDTYLGDKEWFIGNYQVTWADFYWDICSTTLLVLKPGLLDIYPKLVSLRNKVQAIPAISAWILKRPQTKL

Target ORF information:

RefSeq Version	XM_006506398.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus hematopoietic prostaglandin D synthase (Hpgds), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006506398.3

ORF Insert Sequence:

ATGCCTAACT ACAAACTGCT TTATTTTAAT ATGAGGGGAA GAGCCGAAAT TATTCGCTAC 
ATATTCGCTT ATTTGGACAT AAAGTATGAG GATCACAGAA TAGAACAAGC TGACTGGCCT 
AAAATCAAGC CAACTCTTCC ATTTGGCAAA ATCCCTGTTT TGGAGGTGGA AGGACTTACA 
ATCCACCAGA GCCTCGCAAT AGCAAGATAT TTGACCAAAA ACACAGATTT GGCTGGGAAG 
ACAGCGTTGG AGCAATGTCA AGCTGATGCA GTGGTGGACA CGCTGGATGA CTTCATGTCT 
CTCTTCCCAT GGGCAGAGAA AGATCAAGAT CTAAAAGAGC GGATGTTCAA TGAATTGCTC 
ACACATCAAG CACCTCGCCT TCTGAAAGAT TTGGACACAT ACTTAGGAGA CAAAGAGTGG 
TTTATAGGCA ATTATCAGGT AACCTGGGCA GACTTCTACT GGGATATCTG CAGCACCACA 
CTTTTGGTTT TAAAGCCTGG CTTGTTGGAT ATCTACCCCA AACTGGTGTC ATTACGGAAC 
AAAGTCCAAG CTATCCCTGC CATTTCTGCC TGGATACTAA AGAGGCCACA GACAAAACTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hpgds ( NM_019455.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062328.3 Mus musculus hematopoietic prostaglandin D synthase (Hpgds), mRNA.

Price & Availability↑

CloneID	OMu10964
Clone ID Related Accession (Same CDS sequence)	NM_019455.4
Accession Version	NM_019455.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	hematopoietic prostaglandin D synthase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from D82072.1 and AC143330.4. On Jul 18, 2009 this sequence version replaced NM_019455.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK039392.1, AK020246.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGCCTAACT ACAAACTGCT TTATTTTAAT ATGAGGGGAA GAGCCGAAAT TATTCGCTAC 
ATATTCGCTT ATTTGGACAT AAAGTATGAG GATCACAGAA TAGAACAAGC TGACTGGCCT 
AAAATCAAGC CAACTCTTCC ATTTGGCAAA ATCCCTGTTT TGGAGGTGGA AGGACTTACA 
ATCCACCAGA GCCTCGCAAT AGCAAGATAT TTGACCAAAA ACACAGATTT GGCTGGGAAG 
ACAGCGTTGG AGCAATGTCA AGCTGATGCA GTGGTGGACA CGCTGGATGA CTTCATGTCT 
CTCTTCCCAT GGGCAGAGAA AGATCAAGAT CTAAAAGAGC GGATGTTCAA TGAATTGCTC 
ACACATCAAG CACCTCGCCT TCTGAAAGAT TTGGACACAT ACTTAGGAGA CAAAGAGTGG 
TTTATAGGCA ATTATGTAAC CTGGGCAGAC TTCTACTGGG ATATCTGCAG CACCACACTT 
TTGGTTTTAA AGCCTGGCTT GTTGGATATC TACCCCAAAC TGGTGTCATT ACGGAACAAA 
GTCCAAGCTA TCCCTGCCAT TTCTGCCTGG ATACTAAAGA GGCCACAGAC AAAACTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062328.3
CDS	68..667
Translation	MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQSLAIARYLTKNTDLAGKTALEQCQADAVVDTLDDFMSLFPWAEKDQDLKERMFNELLTHQAPRLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPGLLDIYPKLVSLRNKVQAIPAISAWILKRPQTKL

Target ORF information:

RefSeq Version	NM_019455.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus hematopoietic prostaglandin D synthase (Hpgds), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019455.4

ORF Insert Sequence:

ATGCCTAACT ACAAACTGCT TTATTTTAAT ATGAGGGGAA GAGCCGAAAT TATTCGCTAC 
ATATTCGCTT ATTTGGACAT AAAGTATGAG GATCACAGAA TAGAACAAGC TGACTGGCCT 
AAAATCAAGC CAACTCTTCC ATTTGGCAAA ATCCCTGTTT TGGAGGTGGA AGGACTTACA 
ATCCACCAGA GCCTCGCAAT AGCAAGATAT TTGACCAAAA ACACAGATTT GGCTGGGAAG 
ACAGCGTTGG AGCAATGTCA AGCTGATGCA GTGGTGGACA CGCTGGATGA CTTCATGTCT 
CTCTTCCCAT GGGCAGAGAA AGATCAAGAT CTAAAAGAGC GGATGTTCAA TGAATTGCTC 
ACACATCAAG CACCTCGCCT TCTGAAAGAT TTGGACACAT ACTTAGGAGA CAAAGAGTGG 
TTTATAGGCA ATTATGTAAC CTGGGCAGAC TTCTACTGGG ATATCTGCAG CACCACACTT 
TTGGTTTTAA AGCCTGGCTT GTTGGATATC TACCCCAAAC TGGTGTCATT ACGGAACAAA 
GTCCAAGCTA TCCCTGCCAT TTCTGCCTGG ATACTAAAGA GGCCACAGAC AAAACTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hpgds ( XM_006506398.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006506461.1 Mus musculus hematopoietic prostaglandin D synthase (Hpgds), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu37452
Clone ID Related Accession (Same CDS sequence)	XM_006506398.3 , XM_006506398.4
Accession Version	XM_006506398.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	hematopoietic prostaglandin D synthase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006506398.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTAACT ACAAACTGCT TTATTTTAAT ATGAGGGGAA GAGCCGAAAT TATTCGCTAC 
ATATTCGCTT ATTTGGACAT AAAGTATGAG GATCACAGAA TAGAACAAGC TGACTGGCCT 
AAAATCAAGC CAACTCTTCC ATTTGGCAAA ATCCCTGTTT TGGAGGTGGA AGGACTTACA 
ATCCACCAGA GCCTCGCAAT AGCAAGATAT TTGACCAAAA ACACAGATTT GGCTGGGAAG 
ACAGCGTTGG AGCAATGTCA AGCTGATGCA GTGGTGGACA CGCTGGATGA CTTCATGTCT 
CTCTTCCCAT GGGCAGAGAA AGATCAAGAT CTAAAAGAGC GGATGTTCAA TGAATTGCTC 
ACACATCAAG CACCTCGCCT TCTGAAAGAT TTGGACACAT ACTTAGGAGA CAAAGAGTGG 
TTTATAGGCA ATTATCAGGT AACCTGGGCA GACTTCTACT GGGATATCTG CAGCACCACA 
CTTTTGGTTT TAAAGCCTGG CTTGTTGGAT ATCTACCCCA AACTGGTGTC ATTACGGAAC 
AAAGTCCAAG CTATCCCTGC CATTTCTGCC TGGATACTAA AGAGGCCACA GACAAAACTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006506461.1
CDS	319..921
Translation	MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQSLAIARYLTKNTDLAGKTALEQCQADAVVDTLDDFMSLFPWAEKDQDLKERMFNELLTHQAPRLLKDLDTYLGDKEWFIGNYQVTWADFYWDICSTTLLVLKPGLLDIYPKLVSLRNKVQAIPAISAWILKRPQTKL

Target ORF information:

RefSeq Version	XM_006506398.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus hematopoietic prostaglandin D synthase (Hpgds), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006506398.4

ORF Insert Sequence:

ATGCCTAACT ACAAACTGCT TTATTTTAAT ATGAGGGGAA GAGCCGAAAT TATTCGCTAC 
ATATTCGCTT ATTTGGACAT AAAGTATGAG GATCACAGAA TAGAACAAGC TGACTGGCCT 
AAAATCAAGC CAACTCTTCC ATTTGGCAAA ATCCCTGTTT TGGAGGTGGA AGGACTTACA 
ATCCACCAGA GCCTCGCAAT AGCAAGATAT TTGACCAAAA ACACAGATTT GGCTGGGAAG 
ACAGCGTTGG AGCAATGTCA AGCTGATGCA GTGGTGGACA CGCTGGATGA CTTCATGTCT 
CTCTTCCCAT GGGCAGAGAA AGATCAAGAT CTAAAAGAGC GGATGTTCAA TGAATTGCTC 
ACACATCAAG CACCTCGCCT TCTGAAAGAT TTGGACACAT ACTTAGGAGA CAAAGAGTGG 
TTTATAGGCA ATTATCAGGT AACCTGGGCA GACTTCTACT GGGATATCTG CAGCACCACA 
CTTTTGGTTT TAAAGCCTGG CTTGTTGGAT ATCTACCCCA AACTGGTGTC ATTACGGAAC 
AAAGTCCAAG CTATCCCTGC CATTTCTGCC TGGATACTAA AGAGGCCACA GACAAAACTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.
Nature communications67514(2015 Jul)
Nakamura T,Maeda S,Horiguchi K,Maehara T,Aritake K,Choi BI,Iwakura Y,Urade Y,Murata T

Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination.
Nature neuroscience17(12)1682-92(2014 Dec)
Trimarco A,Forese MG,Alfieri V,Lucente A,Brambilla P,Dina G,Pieragostino D,Sacchetta P,Urade Y,Boizet-Bonhoure B,Martinelli Boneschi F,Quattrini A,Taveggia C

Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity.
Proceedings of the National Academy of Sciences of the United States of America103(13)5179-84(2006 Mar)
Trivedi SG,Newson J,Rajakariar R,Jacques TS,Hannon R,Kanaoka Y,Eguchi N,Colville-Nash P,Gilroy DW

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Hpgds cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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