Ccrl2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ccrl2
Entrez Gene ID	54199
Full Name	chemokine (C-C motif) receptor-like 2
Synonyms	1810047I05Rik,Ackr5,CCR11,Cmkbr1l2,E01,L-CCR
General protein information	Preferred Names chemokine (C-C motif) receptor-like 2 Names C-C chemokine receptor-like 2 G-protein coupled beta chemokine receptor chemokine (C-C) receptor 1-like 2 chemokine receptor CCR11 lipopolysaccharide inducible C-C chemokine receptor related lipopolysaccharide-inducible C-C chemokine receptor lipopolysacharide-inducible C-C chemokine receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 F2\|9 60.92 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_017466.5	NP_059494.2	C-C chemokine receptor-like 2
NM_001302376.1	NP_001289305.1	C-C chemokine receptor-like 2
NM_001302377.1	NP_001289306.1	C-C chemokine receptor-like 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCRL2	NP_001124382.1
Mus musculus (house mouse)	Ccrl2	NP_059494.2
Canis lupus familiaris (dog)	LOC484788	XP_005632684.1
Rattus norvegicus (Norway rat)	Ccrl2	NP_001101661.1
Pan troglodytes (chimpanzee)	CCRL2	XP_001149932.2
	LOC713715	XP_001103165.2
Bos taurus (cattle)	LOC515976	NP_001069200.1

Gene Ontology
Bibliography

Related articles in PubMed

Chemokine (C-C Motif) Receptor-Like 2 is not essential for lung injury, lung inflammation, or airway hyperresponsiveness induced by acute exposure to ozone.
Malik F, Cromar KR, Atkins CL, Price RE, Jackson WT, Siddiqui SR, Spencer CY, Mitchell NC, Haque IU, Johnston RA
Physiological reports5(24)(2017 Dec)

The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage.
Del Prete A, Mart?nez-Mu?oz L, Mazzon C, Toffali L, Sozio F, Za L, Bosisio D, Gazzurelli L, Salvi V, Tiberio L, Liberati C, Scanziani E, Vecchi A, Laudanna C, Mellado M, Mantovani A, Sozzani S
Blood130(10)1223-1234(2017 09)

Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.
Zimny S, Pohl R, Rein-Fischboeck L, Haberl EM, Krautbauer S, Weiss TS, Buechler C
Experimental and molecular pathology103(1)1-8(2017 08)

CCRL2 regulates M1/M2 polarization during EAE recovery phase.
Mazzon C, Zanotti L, Wang L, Del Prete A, Fontana E, Salvi V, Poliani PL, Sozzani S
Journal of leukocyte biology99(6)1027-33(2016 06)

The expression and regulation of chemerin in the epidermis.
Banas M, Zegar A, Kwitniewski M, Zabieglo K, Marczynska J, Kapinska-Mrowiecka M, LaJevic M, Zabel BA, Cichy J
PloS one10(2)e0117830(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

upregulation of CCRL2 observed under inflammatory conditions is functional to finely tune CXCR2-mediated neutrophil recruitment at sites of inflammation.
Title: The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage.

CCRL2 mRNA was not significantly changed in murine and human non-alcoholic steatohepatitis liver. CCRL2 was related to the mRNA levels of F4/80, transforming growth factor beta and alpha smooth muscle actin in murine non-alcoholic steatohepatitis.
Title: Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.

chemokine (CC motif) receptor-like 2 should be considered to be a molecule involved in the regulation of the inflammatory response associated with multiple sclerosis.
Title: CCRL2 regulates M1/M2 polarization during EAE recovery phase.

Proinflammatory stimuli upregulate atypical chemerin receptor CCRL2 and VCAM-1 on endothelial cells via NF-kappaB and JAK/STAT intracellular signaling pathways.
Title: Expression, regulation, and function of atypical chemerin receptor CCRL2 on endothelial cells.

Ccrl2(-/-) mice showed normal recruitment of circulating dendritic cells (DC) into the lung, but a defective trafficking of antigen-loaded lung DC to mediastinal lymph nodes.
Title: Nonredundant role of CCRL2 in lung dendritic cell trafficking.

The following Ccrl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccrl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10823	NM_017466.5 Latest version!	Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu10823	NM_001302376.1 Latest version!	Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu10823	NM_001302377.1 Latest version!	Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ccrl2 ( NM_017466.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_059494.2 Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10823
Clone ID Related Accession (Same CDS sequence)	NM_017466.5 , NM_001302376.1 , NM_001302377.1
Accession Version	NM_017466.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Mus musculus(house mouse)
Product	C-C chemokine receptor-like 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK007808.1, AK145946.1 and BC038631.1. On Oct 22, 2014 this sequence version replaced NM_017466.4. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF030185.1, AK007808.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATAACT ACACAGTGGC CCCGGACGAT GAATATGATG TCCTAATCTT AGACGACTAC 
CTGGACAACA GTGGGCCGGA CCAAGTTCCG GCCCCCGAGT TCCTCTCCCC CCAGCAGGTG 
CTGCAGTTCT GCTGCGCGGT GTTTGCGGTG GGTCTCTTGG ACAACGTGCT GGCGGTGTTT 
ATCTTGGTGA AATACAAAGG ACTCAAGAAT CTGGGGAACA TCTACTTCCT AAACCTGGCA 
CTTTCAAACC TGTGTTTCCT GCTTCCCCTG CCGTTCTGGG CCCATACTGC AGCACACGGG 
GAAAGCCCTG GCAATGGGAC CTGTAAAGTT CTTGTCGGAC TCCACTCCTC GGGCTTATAC 
AGCGAGGTGT TTTCCAACAT CCTCCTCCTT GTGCAAGGAT ACAGGGTGTT TTCCCAAGGG 
CGACTGGCCT CCATCTTCAC GACAGTGTCT TGTGGTATTG TTGCGTGCAT CCTGGCATGG 
GCCATGGCTA CTGCGCTCTC TTTGCCCGAG TCTGTGTTTT ATGAGCCTCG GATGGAAAGA 
CAGAAACACA AGTGTGCCTT TGGCAAACCT CACTTCTTGC CAATCGAAGC GCCGCTCTGG 
AAGTACGTTC TGACGTCAAA AATGATCATC TTGGTACTTG CTTTTCCTCT GCTGGTTTTT 
ATAATCTGCT GCAGGCAACT GAGGAGAAGG CAGAGCTTCA GGGAGAGACA GTACGACCTC 
CACAAGCCGG CTCTTGTCAT AACGGGCGTG TTCCTTTTGA TGTGGGCGCC TTACAACACT 
GTGCTTTTCC TGTCTGCTTT CCAGGAACAC TTGTCCCTGC AGGATGAGAA GAGCAGCTAC 
CACCTGGACG CAAGTGTTCA GGTCACACAG CTGGTAGCGA CCACCCACTG CTGCGTCAAC 
CCGCTGCTCT ATTTGCTTCT TGACCGGAAG GCCTTTATGA GATACCTTCG CAGCCTGTTC 
CCACGGTGCA ATGATATCCC CTATCAAAGT AGTGGAGGCT ATCAGCAAGC GCCTCCAAGG 
GAAGGTCATG GCAGGCCCAT TGAACTGTAC AGCAATTTGC ATCAAAGGCA GGATATAATA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059494.2
CDS	517..1599
Translation	MDNYTVAPDDEYDVLILDDYLDNSGPDQVPAPEFLSPQQVLQFCCAVFAVGLLDNVLAVFILVKYKGLKNLGNIYFLNLALSNLCFLLPLPFWAHTAAHGESPGNGTCKVLVGLHSSGLYSEVFSNILLLVQGYRVFSQGRLASIFTTVSCGIVACILAWAMATALSLPESVFYEPRMERQKHKCAFGKPHFLPIEAPLWKYVLTSKMIILVLAFPLLVFIICCRQLRRRQSFRERQYDLHKPALVITGVFLLMWAPYNTVLFLSAFQEHLSLQDEKSSYHLDASVQVTQLVATTHCCVNPLLYLLLDRKAFMRYLRSLFPRCNDIPYQSSGGYQQAPPREGHGRPIELYSNLHQRQDII

Target ORF information:

RefSeq Version	NM_017466.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017466.5

ORF Insert Sequence:

ATGGATAACT ACACAGTGGC CCCGGACGAT GAATATGATG TCCTAATCTT AGACGACTAC 
CTGGACAACA GTGGGCCGGA CCAAGTTCCG GCCCCCGAGT TCCTCTCCCC CCAGCAGGTG 
CTGCAGTTCT GCTGCGCGGT GTTTGCGGTG GGTCTCTTGG ACAACGTGCT GGCGGTGTTT 
ATCTTGGTGA AATACAAAGG ACTCAAGAAT CTGGGGAACA TCTACTTCCT AAACCTGGCA 
CTTTCAAACC TGTGTTTCCT GCTTCCCCTG CCGTTCTGGG CCCATACTGC AGCACACGGG 
GAAAGCCCTG GCAATGGGAC CTGTAAAGTT CTTGTCGGAC TCCACTCCTC GGGCTTATAC 
AGCGAGGTGT TTTCCAACAT CCTCCTCCTT GTGCAAGGAT ACAGGGTGTT TTCCCAAGGG 
CGACTGGCCT CCATCTTCAC GACAGTGTCT TGTGGTATTG TTGCGTGCAT CCTGGCATGG 
GCCATGGCTA CTGCGCTCTC TTTGCCCGAG TCTGTGTTTT ATGAGCCTCG GATGGAAAGA 
CAGAAACACA AGTGTGCCTT TGGCAAACCT CACTTCTTGC CAATCGAAGC GCCGCTCTGG 
AAGTACGTTC TGACGTCAAA AATGATCATC TTGGTACTTG CTTTTCCTCT GCTGGTTTTT 
ATAATCTGCT GCAGGCAACT GAGGAGAAGG CAGAGCTTCA GGGAGAGACA GTACGACCTC 
CACAAGCCGG CTCTTGTCAT AACGGGCGTG TTCCTTTTGA TGTGGGCGCC TTACAACACT 
GTGCTTTTCC TGTCTGCTTT CCAGGAACAC TTGTCCCTGC AGGATGAGAA GAGCAGCTAC 
CACCTGGACG CAAGTGTTCA GGTCACACAG CTGGTAGCGA CCACCCACTG CTGCGTCAAC 
CCGCTGCTCT ATTTGCTTCT TGACCGGAAG GCCTTTATGA GATACCTTCG CAGCCTGTTC 
CCACGGTGCA ATGATATCCC CTATCAAAGT AGTGGAGGCT ATCAGCAAGC GCCTCCAAGG 
GAAGGTCATG GCAGGCCCAT TGAACTGTAC AGCAATTTGC ATCAAAGGCA GGATATAATA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ccrl2 ( NM_001302376.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289305.1 Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu10823
Clone ID Related Accession (Same CDS sequence)	NM_017466.5 , NM_001302376.1 , NM_001302377.1
Accession Version	NM_001302376.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Mus musculus(house mouse)
Product	C-C chemokine receptor-like 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY162594.1, AK007808.1, AK145946.1 and BC038631.1. On Oct 22, 2014 this sequence version replaced XM_006512185.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC038631.1, AB009384.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATAACT ACACAGTGGC CCCGGACGAT GAATATGATG TCCTAATCTT AGACGACTAC 
CTGGACAACA GTGGGCCGGA CCAAGTTCCG GCCCCCGAGT TCCTCTCCCC CCAGCAGGTG 
CTGCAGTTCT GCTGCGCGGT GTTTGCGGTG GGTCTCTTGG ACAACGTGCT GGCGGTGTTT 
ATCTTGGTGA AATACAAAGG ACTCAAGAAT CTGGGGAACA TCTACTTCCT AAACCTGGCA 
CTTTCAAACC TGTGTTTCCT GCTTCCCCTG CCGTTCTGGG CCCATACTGC AGCACACGGG 
GAAAGCCCTG GCAATGGGAC CTGTAAAGTT CTTGTCGGAC TCCACTCCTC GGGCTTATAC 
AGCGAGGTGT TTTCCAACAT CCTCCTCCTT GTGCAAGGAT ACAGGGTGTT TTCCCAAGGG 
CGACTGGCCT CCATCTTCAC GACAGTGTCT TGTGGTATTG TTGCGTGCAT CCTGGCATGG 
GCCATGGCTA CTGCGCTCTC TTTGCCCGAG TCTGTGTTTT ATGAGCCTCG GATGGAAAGA 
CAGAAACACA AGTGTGCCTT TGGCAAACCT CACTTCTTGC CAATCGAAGC GCCGCTCTGG 
AAGTACGTTC TGACGTCAAA AATGATCATC TTGGTACTTG CTTTTCCTCT GCTGGTTTTT 
ATAATCTGCT GCAGGCAACT GAGGAGAAGG CAGAGCTTCA GGGAGAGACA GTACGACCTC 
CACAAGCCGG CTCTTGTCAT AACGGGCGTG TTCCTTTTGA TGTGGGCGCC TTACAACACT 
GTGCTTTTCC TGTCTGCTTT CCAGGAACAC TTGTCCCTGC AGGATGAGAA GAGCAGCTAC 
CACCTGGACG CAAGTGTTCA GGTCACACAG CTGGTAGCGA CCACCCACTG CTGCGTCAAC 
CCGCTGCTCT ATTTGCTTCT TGACCGGAAG GCCTTTATGA GATACCTTCG CAGCCTGTTC 
CCACGGTGCA ATGATATCCC CTATCAAAGT AGTGGAGGCT ATCAGCAAGC GCCTCCAAGG 
GAAGGTCATG GCAGGCCCAT TGAACTGTAC AGCAATTTGC ATCAAAGGCA GGATATAATA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289305.1
CDS	267..1349
Translation	MDNYTVAPDDEYDVLILDDYLDNSGPDQVPAPEFLSPQQVLQFCCAVFAVGLLDNVLAVFILVKYKGLKNLGNIYFLNLALSNLCFLLPLPFWAHTAAHGESPGNGTCKVLVGLHSSGLYSEVFSNILLLVQGYRVFSQGRLASIFTTVSCGIVACILAWAMATALSLPESVFYEPRMERQKHKCAFGKPHFLPIEAPLWKYVLTSKMIILVLAFPLLVFIICCRQLRRRQSFRERQYDLHKPALVITGVFLLMWAPYNTVLFLSAFQEHLSLQDEKSSYHLDASVQVTQLVATTHCCVNPLLYLLLDRKAFMRYLRSLFPRCNDIPYQSSGGYQQAPPREGHGRPIELYSNLHQRQDII

Target ORF information:

RefSeq Version	NM_001302376.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302376.1

ORF Insert Sequence:

ATGGATAACT ACACAGTGGC CCCGGACGAT GAATATGATG TCCTAATCTT AGACGACTAC 
CTGGACAACA GTGGGCCGGA CCAAGTTCCG GCCCCCGAGT TCCTCTCCCC CCAGCAGGTG 
CTGCAGTTCT GCTGCGCGGT GTTTGCGGTG GGTCTCTTGG ACAACGTGCT GGCGGTGTTT 
ATCTTGGTGA AATACAAAGG ACTCAAGAAT CTGGGGAACA TCTACTTCCT AAACCTGGCA 
CTTTCAAACC TGTGTTTCCT GCTTCCCCTG CCGTTCTGGG CCCATACTGC AGCACACGGG 
GAAAGCCCTG GCAATGGGAC CTGTAAAGTT CTTGTCGGAC TCCACTCCTC GGGCTTATAC 
AGCGAGGTGT TTTCCAACAT CCTCCTCCTT GTGCAAGGAT ACAGGGTGTT TTCCCAAGGG 
CGACTGGCCT CCATCTTCAC GACAGTGTCT TGTGGTATTG TTGCGTGCAT CCTGGCATGG 
GCCATGGCTA CTGCGCTCTC TTTGCCCGAG TCTGTGTTTT ATGAGCCTCG GATGGAAAGA 
CAGAAACACA AGTGTGCCTT TGGCAAACCT CACTTCTTGC CAATCGAAGC GCCGCTCTGG 
AAGTACGTTC TGACGTCAAA AATGATCATC TTGGTACTTG CTTTTCCTCT GCTGGTTTTT 
ATAATCTGCT GCAGGCAACT GAGGAGAAGG CAGAGCTTCA GGGAGAGACA GTACGACCTC 
CACAAGCCGG CTCTTGTCAT AACGGGCGTG TTCCTTTTGA TGTGGGCGCC TTACAACACT 
GTGCTTTTCC TGTCTGCTTT CCAGGAACAC TTGTCCCTGC AGGATGAGAA GAGCAGCTAC 
CACCTGGACG CAAGTGTTCA GGTCACACAG CTGGTAGCGA CCACCCACTG CTGCGTCAAC 
CCGCTGCTCT ATTTGCTTCT TGACCGGAAG GCCTTTATGA GATACCTTCG CAGCCTGTTC 
CCACGGTGCA ATGATATCCC CTATCAAAGT AGTGGAGGCT ATCAGCAAGC GCCTCCAAGG 
GAAGGTCATG GCAGGCCCAT TGAACTGTAC AGCAATTTGC ATCAAAGGCA GGATATAATA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ccrl2 ( NM_001302377.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001289306.1 Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu10823
Clone ID Related Accession (Same CDS sequence)	NM_017466.5 , NM_001302376.1 , NM_001302377.1
Accession Version	NM_001302377.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-05
Organism	Mus musculus(house mouse)
Product	C-C chemokine receptor-like 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC118727.7, BY162594.1, AK007808.1, AK145946.1 and BC038631.1. On Oct 22, 2014 this sequence version replaced XM_006512186.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CB598882.1, CA580283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATAACT ACACAGTGGC CCCGGACGAT GAATATGATG TCCTAATCTT AGACGACTAC 
CTGGACAACA GTGGGCCGGA CCAAGTTCCG GCCCCCGAGT TCCTCTCCCC CCAGCAGGTG 
CTGCAGTTCT GCTGCGCGGT GTTTGCGGTG GGTCTCTTGG ACAACGTGCT GGCGGTGTTT 
ATCTTGGTGA AATACAAAGG ACTCAAGAAT CTGGGGAACA TCTACTTCCT AAACCTGGCA 
CTTTCAAACC TGTGTTTCCT GCTTCCCCTG CCGTTCTGGG CCCATACTGC AGCACACGGG 
GAAAGCCCTG GCAATGGGAC CTGTAAAGTT CTTGTCGGAC TCCACTCCTC GGGCTTATAC 
AGCGAGGTGT TTTCCAACAT CCTCCTCCTT GTGCAAGGAT ACAGGGTGTT TTCCCAAGGG 
CGACTGGCCT CCATCTTCAC GACAGTGTCT TGTGGTATTG TTGCGTGCAT CCTGGCATGG 
GCCATGGCTA CTGCGCTCTC TTTGCCCGAG TCTGTGTTTT ATGAGCCTCG GATGGAAAGA 
CAGAAACACA AGTGTGCCTT TGGCAAACCT CACTTCTTGC CAATCGAAGC GCCGCTCTGG 
AAGTACGTTC TGACGTCAAA AATGATCATC TTGGTACTTG CTTTTCCTCT GCTGGTTTTT 
ATAATCTGCT GCAGGCAACT GAGGAGAAGG CAGAGCTTCA GGGAGAGACA GTACGACCTC 
CACAAGCCGG CTCTTGTCAT AACGGGCGTG TTCCTTTTGA TGTGGGCGCC TTACAACACT 
GTGCTTTTCC TGTCTGCTTT CCAGGAACAC TTGTCCCTGC AGGATGAGAA GAGCAGCTAC 
CACCTGGACG CAAGTGTTCA GGTCACACAG CTGGTAGCGA CCACCCACTG CTGCGTCAAC 
CCGCTGCTCT ATTTGCTTCT TGACCGGAAG GCCTTTATGA GATACCTTCG CAGCCTGTTC 
CCACGGTGCA ATGATATCCC CTATCAAAGT AGTGGAGGCT ATCAGCAAGC GCCTCCAAGG 
GAAGGTCATG GCAGGCCCAT TGAACTGTAC AGCAATTTGC ATCAAAGGCA GGATATAATA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289306.1
CDS	169..1251
Translation	MDNYTVAPDDEYDVLILDDYLDNSGPDQVPAPEFLSPQQVLQFCCAVFAVGLLDNVLAVFILVKYKGLKNLGNIYFLNLALSNLCFLLPLPFWAHTAAHGESPGNGTCKVLVGLHSSGLYSEVFSNILLLVQGYRVFSQGRLASIFTTVSCGIVACILAWAMATALSLPESVFYEPRMERQKHKCAFGKPHFLPIEAPLWKYVLTSKMIILVLAFPLLVFIICCRQLRRRQSFRERQYDLHKPALVITGVFLLMWAPYNTVLFLSAFQEHLSLQDEKSSYHLDASVQVTQLVATTHCCVNPLLYLLLDRKAFMRYLRSLFPRCNDIPYQSSGGYQQAPPREGHGRPIELYSNLHQRQDII

Target ORF information:

RefSeq Version	NM_001302377.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus chemokine (C-C motif) receptor-like 2 (Ccrl2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302377.1

ORF Insert Sequence:

ATGGATAACT ACACAGTGGC CCCGGACGAT GAATATGATG TCCTAATCTT AGACGACTAC 
CTGGACAACA GTGGGCCGGA CCAAGTTCCG GCCCCCGAGT TCCTCTCCCC CCAGCAGGTG 
CTGCAGTTCT GCTGCGCGGT GTTTGCGGTG GGTCTCTTGG ACAACGTGCT GGCGGTGTTT 
ATCTTGGTGA AATACAAAGG ACTCAAGAAT CTGGGGAACA TCTACTTCCT AAACCTGGCA 
CTTTCAAACC TGTGTTTCCT GCTTCCCCTG CCGTTCTGGG CCCATACTGC AGCACACGGG 
GAAAGCCCTG GCAATGGGAC CTGTAAAGTT CTTGTCGGAC TCCACTCCTC GGGCTTATAC 
AGCGAGGTGT TTTCCAACAT CCTCCTCCTT GTGCAAGGAT ACAGGGTGTT TTCCCAAGGG 
CGACTGGCCT CCATCTTCAC GACAGTGTCT TGTGGTATTG TTGCGTGCAT CCTGGCATGG 
GCCATGGCTA CTGCGCTCTC TTTGCCCGAG TCTGTGTTTT ATGAGCCTCG GATGGAAAGA 
CAGAAACACA AGTGTGCCTT TGGCAAACCT CACTTCTTGC CAATCGAAGC GCCGCTCTGG 
AAGTACGTTC TGACGTCAAA AATGATCATC TTGGTACTTG CTTTTCCTCT GCTGGTTTTT 
ATAATCTGCT GCAGGCAACT GAGGAGAAGG CAGAGCTTCA GGGAGAGACA GTACGACCTC 
CACAAGCCGG CTCTTGTCAT AACGGGCGTG TTCCTTTTGA TGTGGGCGCC TTACAACACT 
GTGCTTTTCC TGTCTGCTTT CCAGGAACAC TTGTCCCTGC AGGATGAGAA GAGCAGCTAC 
CACCTGGACG CAAGTGTTCA GGTCACACAG CTGGTAGCGA CCACCCACTG CTGCGTCAAC 
CCGCTGCTCT ATTTGCTTCT TGACCGGAAG GCCTTTATGA GATACCTTCG CAGCCTGTTC 
CCACGGTGCA ATGATATCCC CTATCAAAGT AGTGGAGGCT ATCAGCAAGC GCCTCCAAGG 
GAAGGTCATG GCAGGCCCAT TGAACTGTAC AGCAATTTGC ATCAAAGGCA GGATATAATA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chemokine (C-C Motif) Receptor-Like 2 is not essential for lung injury, lung inflammation, or airway hyperresponsiveness induced by acute exposure to ozone.
Physiological reports5(24)(2017 Dec)
Malik F,Cromar KR,Atkins CL,Price RE,Jackson WT,Siddiqui SR,Spencer CY,Mitchell NC,Haque IU,Johnston RA

The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage.
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Ccrl2 cDNA ORF clone, Mus musculus(house mouse)

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ORF Insert Sequence:

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ORF Insert Sequence:

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