Actr1a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Actr1a
Entrez Gene ID	54130
Full Name	ARP1 actin-related protein 1A, centractin alpha
Synonyms	Arp1,alpha-Arp1
General protein information	Preferred Names ARP1 actin-related protein 1A, centractin alpha Names alpha-centractin ARP1 actin-related protein 1 homolog A, centractin alpha Arp1 centractin alpha Arp1 contractin alpha actin-RPV actin-related protein 1 alpha actin-related protein 1 homolog A centractin centrosome-associated actin homolog
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 19 Map Location: 19\|19 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001365070.1	NP_001351999.1	alpha-centractin isoform 2
NM_016860.1	NP_058556.1	alpha-centractin
NM_016860.2	NP_058556.1	alpha-centractin isoform 1

Pathways from BioSystems

Homologies

	ACTR1A	XP_001112871.1
Pan troglodytes (chimpanzee)	ACTR1A	XP_521593.1
Canis lupus familiaris (dog)	ACTR1A	NP_001003164.1
Bos taurus (cattle)	ACTR1A	NP_001180177.1
Rattus norvegicus (Norway rat)	Actr1a	NP_001099834.1
Homo sapiens (human)	ACTR1A	NP_005727.1
Gallus gallus (chicken)	ACTR1A	NP_001007949.1
Caenorhabditis elegans (roundworm)	arp-1	NP_497108.2
Xenopus tropicalis (tropical clawed frog)	actr1a	NP_001163973.1
Mus musculus (house mouse)	Actr1a	NP_058556.1
Drosophila melanogaster (fruit fly)	Arp1	NP_524331.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002127	XP_320908.2

Gene Ontology
Bibliography

Related articles in PubMed

Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi.
Clarkson YL, Gillespie T, Perkins EM, Lyndon AR, Jackson M
Human molecular genetics19(18)3634-41(2010 Sep)

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, M?bius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)

PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum.
Lin SS, Bassik MC, Suh H, Nishino M, Arroyo JD, Hahn WC, Korsmeyer SJ, Roberts TM
The Journal of biological chemistry281(32)23003-12(2006 Aug)

Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1.
Eckley DM, Schroer TA
Molecular biology of the cell14(7)2645-54(2003 Jul)

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T, Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA, Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts P, Muramatsu M, Okazaki Y, Kawai J, Hayashizaki Y
Genome research13(6B)1273-89(2003 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Beta-III spectrin mutation L253P interferes with binding to Arp1 and protein trafficking from the Golgi.
Title: Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi.

The following Actr1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Actr1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10770	NM_016860.2 Latest version!	Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu84379	NM_001365070.1 Latest version!	Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu10770	NM_016860.1	Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Actr1a ( NM_016860.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058556.1 Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), mRNA.

Price & Availability↑

CloneID	OMu10770
Clone ID Related Accession (Same CDS sequence)	NM_016860.1 , NM_016860.2
Accession Version	NM_016860.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-25
Organism	Mus musculus(house mouse)
Product	alpha-centractin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB010297.1. On May 4, 2006 this sequence version replaced XM_981021.1. ##Evidence-Data-START## Transcript exon combination :: AB010297.1, AK088062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCCT ACGATGTGAT CGCCAACCAG CCTGTTGTGA TCGACAACGG ATCCGGTGTG 
ATTAAAGCTG GCTTTGCTGG TGATCAGATC CCCAAATACT GCTTTCCAAA CTATGTGGGC 
AGACCCAAAC ATGTTCGTGT CATGGCAGGA GCCCTGGAAG GTGACATCTT CATTGGCCCC 
AAAGCGGAGG AGCACCGGGG GCTGCTGTCA ATCCGTTACC CCATGGAACA TGGCATCGTC 
AAGGACTGGA ACGACATGGA ACGCATCTGG CAATACGTCT ACTCTAAGGA CCAGCTGCAG 
ACTTTCTCAG AGGAGCATCC TGTGCTCCTA ACGGAGGCAC CTTTAAACCC TCGGAAAAAC 
CGGGAGCGAG CTGCAGAAGT CTTCTTCGAG ACCTTCAATG TGCCGGCCCT CTTCATCTCC 
ATGCAAGCCG TGCTGAGCCT TTATGCCACG GGCAGAACCA CAGGCGTGGT GTTGGATTCT 
GGGGATGGTG TCACCCATGC AGTCCCGATT TATGAAGGCT TCGCCATGCC TCACTCCATC 
ATGCGCATCG ACATCGCTGG CCGGGATGTC TCACGCTTCC TCCGCCTCTA CCTACGGAAG 
GAGGGCTATG ATTTCCACTC CTCCTCTGAG TTTGAGATTG TCAAGGCCAT AAAGGAAAGA 
GCTTGCTACC TGTCCATAAA CCCCCAGAAG GATGAGACAC TGGAGACAGA GAAGGCTCAG 
TACTACCTGC CCGATGGCAG CACCATTGAG ATTGGCCCTT CCCGGTTCCG GGCCCCTGAG 
CTGCTGTTCA GGCCGGACTT GATTGGCGAG GAGAGTGAAG GCATCCACGA GGTGCTGGTG 
TTTGCTATCC AGAAGTCAGA CATGGATTTA CGGCGTACAC TGTTTTCCAA CATTGTCCTC 
TCAGGAGGTT CTACCCTGTT CAAAGGTTTT GGAGACAGGC TACTGAGTGA AGTGAAGAAA 
CTAGCTCCAA AAGACGTGAA GATCAGGATA TCTGCACCCC AGGAGAGACT GTATTCCACA 
TGGATTGGAG GTTCTATCCT TGCTTCCCTG GACACCTTTA AGAAGATGTG GGTCTCTAAG 
AAAGAATATG AAGAAGACGG TGCCCGATCC ATCCACAGGA AAACCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058556.1
CDS	59..1189
Translation	MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF

Target ORF information:

RefSeq Version	NM_016860.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016860.1

ORF Insert Sequence:

ATGGAGTCCT ACGATGTGAT CGCCAACCAG CCTGTTGTGA TCGACAACGG ATCCGGTGTG 
ATTAAAGCTG GCTTTGCTGG TGATCAGATC CCCAAATACT GCTTTCCAAA CTATGTGGGC 
AGACCCAAAC ATGTTCGTGT CATGGCAGGA GCCCTGGAAG GTGACATCTT CATTGGCCCC 
AAAGCGGAGG AGCACCGGGG GCTGCTGTCA ATCCGTTACC CCATGGAACA TGGCATCGTC 
AAGGACTGGA ACGACATGGA ACGCATCTGG CAATACGTCT ACTCTAAGGA CCAGCTGCAG 
ACTTTCTCAG AGGAGCATCC TGTGCTCCTA ACGGAGGCAC CTTTAAACCC TCGGAAAAAC 
CGGGAGCGAG CTGCAGAAGT CTTCTTCGAG ACCTTCAATG TGCCGGCCCT CTTCATCTCC 
ATGCAAGCCG TGCTGAGCCT TTATGCCACG GGCAGAACCA CAGGCGTGGT GTTGGATTCT 
GGGGATGGTG TCACCCATGC AGTCCCGATT TATGAAGGCT TCGCCATGCC TCACTCCATC 
ATGCGCATCG ACATCGCTGG CCGGGATGTC TCACGCTTCC TCCGCCTCTA CCTACGGAAG 
GAGGGCTATG ATTTCCACTC CTCCTCTGAG TTTGAGATTG TCAAGGCCAT AAAGGAAAGA 
GCTTGCTACC TGTCCATAAA CCCCCAGAAG GATGAGACAC TGGAGACAGA GAAGGCTCAG 
TACTACCTGC CCGATGGCAG CACCATTGAG ATTGGCCCTT CCCGGTTCCG GGCCCCTGAG 
CTGCTGTTCA GGCCGGACTT GATTGGCGAG GAGAGTGAAG GCATCCACGA GGTGCTGGTG 
TTTGCTATCC AGAAGTCAGA CATGGATTTA CGGCGTACAC TGTTTTCCAA CATTGTCCTC 
TCAGGAGGTT CTACCCTGTT CAAAGGTTTT GGAGACAGGC TACTGAGTGA AGTGAAGAAA 
CTAGCTCCAA AAGACGTGAA GATCAGGATA TCTGCACCCC AGGAGAGACT GTATTCCACA 
TGGATTGGAG GTTCTATCCT TGCTTCCCTG GACACCTTTA AGAAGATGTG GGTCTCTAAG 
AAAGAATATG AAGAAGACGG TGCCCGATCC ATCCACAGGA AAACCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Actr1a ( NM_016860.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058556.1 Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10770
Clone ID Related Accession (Same CDS sequence)	NM_016860.1 , NM_016860.2
Accession Version	NM_016860.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	alpha-centractin isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY794369.1, AB010297.1 and CD776146.1. On Jul 24, 2018 this sequence version replaced NM_016860.1. ##Evidence-Data-START## Transcript exon combination :: AK167450.1, SRR7345562.4696985.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTCCT ACGATGTGAT CGCCAACCAG CCTGTTGTGA TCGACAACGG ATCCGGTGTG 
ATTAAAGCTG GCTTTGCTGG TGATCAGATC CCCAAATACT GCTTTCCAAA CTATGTGGGC 
AGACCCAAAC ATGTTCGTGT CATGGCAGGA GCCCTGGAAG GTGACATCTT CATTGGCCCC 
AAAGCGGAGG AGCACCGGGG GCTGCTGTCA ATCCGTTACC CCATGGAACA TGGCATCGTC 
AAGGACTGGA ACGACATGGA ACGCATCTGG CAATACGTCT ACTCTAAGGA CCAGCTGCAG 
ACTTTCTCAG AGGAGCATCC TGTGCTCCTA ACGGAGGCAC CTTTAAACCC TCGGAAAAAC 
CGGGAGCGAG CTGCAGAAGT CTTCTTCGAG ACCTTCAATG TGCCGGCCCT CTTCATCTCC 
ATGCAAGCCG TGCTGAGCCT TTATGCCACG GGCAGAACCA CAGGCGTGGT GTTGGATTCT 
GGGGATGGTG TCACCCATGC AGTCCCGATT TATGAAGGCT TCGCCATGCC TCACTCCATC 
ATGCGCATCG ACATCGCTGG CCGGGATGTC TCACGCTTCC TCCGCCTCTA CCTACGGAAG 
GAGGGCTATG ATTTCCACTC CTCCTCTGAG TTTGAGATTG TCAAGGCCAT AAAGGAAAGA 
GCTTGCTACC TGTCCATAAA CCCCCAGAAG GATGAGACAC TGGAGACAGA GAAGGCTCAG 
TACTACCTGC CCGATGGCAG CACCATTGAG ATTGGCCCTT CCCGGTTCCG GGCCCCTGAG 
CTGCTGTTCA GGCCGGACTT GATTGGCGAG GAGAGTGAAG GCATCCACGA GGTGCTGGTG 
TTTGCTATCC AGAAGTCAGA CATGGATTTA CGGCGTACAC TGTTTTCCAA CATTGTCCTC 
TCAGGAGGTT CTACCCTGTT CAAAGGTTTT GGAGACAGGC TACTGAGTGA AGTGAAGAAA 
CTAGCTCCAA AAGACGTGAA GATCAGGATA TCTGCACCCC AGGAGAGACT GTATTCCACA 
TGGATTGGAG GTTCTATCCT TGCTTCCCTG GACACCTTTA AGAAGATGTG GGTCTCTAAG 
AAAGAATATG AAGAAGACGG TGCCCGATCC ATCCACAGGA AAACCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058556.1
CDS	65..1195
Translation	MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF

Target ORF information:

RefSeq Version	NM_016860.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016860.2

ORF Insert Sequence:

ATGGAGTCCT ACGATGTGAT CGCCAACCAG CCTGTTGTGA TCGACAACGG ATCCGGTGTG 
ATTAAAGCTG GCTTTGCTGG TGATCAGATC CCCAAATACT GCTTTCCAAA CTATGTGGGC 
AGACCCAAAC ATGTTCGTGT CATGGCAGGA GCCCTGGAAG GTGACATCTT CATTGGCCCC 
AAAGCGGAGG AGCACCGGGG GCTGCTGTCA ATCCGTTACC CCATGGAACA TGGCATCGTC 
AAGGACTGGA ACGACATGGA ACGCATCTGG CAATACGTCT ACTCTAAGGA CCAGCTGCAG 
ACTTTCTCAG AGGAGCATCC TGTGCTCCTA ACGGAGGCAC CTTTAAACCC TCGGAAAAAC 
CGGGAGCGAG CTGCAGAAGT CTTCTTCGAG ACCTTCAATG TGCCGGCCCT CTTCATCTCC 
ATGCAAGCCG TGCTGAGCCT TTATGCCACG GGCAGAACCA CAGGCGTGGT GTTGGATTCT 
GGGGATGGTG TCACCCATGC AGTCCCGATT TATGAAGGCT TCGCCATGCC TCACTCCATC 
ATGCGCATCG ACATCGCTGG CCGGGATGTC TCACGCTTCC TCCGCCTCTA CCTACGGAAG 
GAGGGCTATG ATTTCCACTC CTCCTCTGAG TTTGAGATTG TCAAGGCCAT AAAGGAAAGA 
GCTTGCTACC TGTCCATAAA CCCCCAGAAG GATGAGACAC TGGAGACAGA GAAGGCTCAG 
TACTACCTGC CCGATGGCAG CACCATTGAG ATTGGCCCTT CCCGGTTCCG GGCCCCTGAG 
CTGCTGTTCA GGCCGGACTT GATTGGCGAG GAGAGTGAAG GCATCCACGA GGTGCTGGTG 
TTTGCTATCC AGAAGTCAGA CATGGATTTA CGGCGTACAC TGTTTTCCAA CATTGTCCTC 
TCAGGAGGTT CTACCCTGTT CAAAGGTTTT GGAGACAGGC TACTGAGTGA AGTGAAGAAA 
CTAGCTCCAA AAGACGTGAA GATCAGGATA TCTGCACCCC AGGAGAGACT GTATTCCACA 
TGGATTGGAG GTTCTATCCT TGCTTCCCTG GACACCTTTA AGAAGATGTG GGTCTCTAAG 
AAAGAATATG AAGAAGACGG TGCCCGATCC ATCCACAGGA AAACCTTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Actr1a ( NM_001365070.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001351999.1 Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu84379
Clone ID Related Accession (Same CDS sequence)	NM_001365070.1
Accession Version	NM_001365070.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	alpha-centractin isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY794369.1, AK019518.1 and CD776146.1. ##Evidence-Data-START## Transcript exon combination :: AK019518.1, SRR7345562.4864080.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTCCT ACGATGTGAT CGCCAACCAG CCTGTTGTGA TCGACAACGG ATCCGGTGTG 
ATTAAAGCTG GCTTTGCTGG TGATCAGATC CCCAAATACT GCTTTCCAAA CTATGTGGGC 
AGACCCAAAC ATGTTCGTGT CATGGCAGGA GCCCTGGAAG GTGACATCTT CATTGGCCCC 
AAAGCGGAGG AGCACCGGGG GCTGCTGTCA ATCCGTTACC CCATGGAACA TGGCATCGTC 
AAGGACTGGA ACGACATGGA ACGCATCTGG CAATACGTCT ACTCTAAGGA CCAGCTGCAG 
ACTTTCTCAG AGGAGCATCC TGTGCTCCTA ACGGAGGCAC CTTTAAACCC TCGGAAAAAC 
CGGGAGCGAG CTGCAGAAGT CTTCTTCGAG ACCTTCAATG TGCCGGCCCT CTTCATCTCC 
ATGCAAGCCG TGCTGAGCCT TTATGCCACG GGCAGAACCA CAGGCGTGGT GTTGGATTCT 
GGGGATGGTG TCACCCATGC AGTCCCGATT TATGAAGGCT TCGCCATGCC TCACTCCATC 
ATGCGCATCG ACATCGCTGG CCGGGATGTC TCACGCTTCC TCCGCCTCTA CCTACGGAAG 
GAGGGCTATG ATTTCCACTC CTCCTCTGAG TTTGAGATTG TCAAGGCCAT AAAGGAAAGA 
GCTTGCTACC TGTCCATAAA CCCCCAGAAG GATGAGACAC TGGAGACAGA GAAGGCTCAG 
TACTACCTGC CCGATGGCAG CACCATTGAG ATTGGCCCTT CCCGGTTCCG GGCCCCTGAG 
CTGCTGTTCA GGCCGGACTT GATTGGCGAG GAGAGTGAAG GCATCCACGA GGTGCTGGTG 
TTTGCTATCC AGAAGTCAGA CATGGATTTA CGGCGTACAC TGTTTTCCAA CATTGTCCTC 
TCAGGAGGTT CTACCCTGTT CAAAGATATC TGCACCCCAG GAGAGACTGT ATTCCACATG 
GATTGGAGGT TCTATCCTTG CTTCCCTGGA CACCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001351999.1
CDS	65..1063
Translation	MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKDICTPGETVFHMDWRFYPCFPGHL

Target ORF information:

RefSeq Version	NM_001365070.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ARP1 actin-related protein 1A, centractin alpha (Actr1a), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001365070.1

ORF Insert Sequence:

ATGGAGTCCT ACGATGTGAT CGCCAACCAG CCTGTTGTGA TCGACAACGG ATCCGGTGTG 
ATTAAAGCTG GCTTTGCTGG TGATCAGATC CCCAAATACT GCTTTCCAAA CTATGTGGGC 
AGACCCAAAC ATGTTCGTGT CATGGCAGGA GCCCTGGAAG GTGACATCTT CATTGGCCCC 
AAAGCGGAGG AGCACCGGGG GCTGCTGTCA ATCCGTTACC CCATGGAACA TGGCATCGTC 
AAGGACTGGA ACGACATGGA ACGCATCTGG CAATACGTCT ACTCTAAGGA CCAGCTGCAG 
ACTTTCTCAG AGGAGCATCC TGTGCTCCTA ACGGAGGCAC CTTTAAACCC TCGGAAAAAC 
CGGGAGCGAG CTGCAGAAGT CTTCTTCGAG ACCTTCAATG TGCCGGCCCT CTTCATCTCC 
ATGCAAGCCG TGCTGAGCCT TTATGCCACG GGCAGAACCA CAGGCGTGGT GTTGGATTCT 
GGGGATGGTG TCACCCATGC AGTCCCGATT TATGAAGGCT TCGCCATGCC TCACTCCATC 
ATGCGCATCG ACATCGCTGG CCGGGATGTC TCACGCTTCC TCCGCCTCTA CCTACGGAAG 
GAGGGCTATG ATTTCCACTC CTCCTCTGAG TTTGAGATTG TCAAGGCCAT AAAGGAAAGA 
GCTTGCTACC TGTCCATAAA CCCCCAGAAG GATGAGACAC TGGAGACAGA GAAGGCTCAG 
TACTACCTGC CCGATGGCAG CACCATTGAG ATTGGCCCTT CCCGGTTCCG GGCCCCTGAG 
CTGCTGTTCA GGCCGGACTT GATTGGCGAG GAGAGTGAAG GCATCCACGA GGTGCTGGTG 
TTTGCTATCC AGAAGTCAGA CATGGATTTA CGGCGTACAC TGTTTTCCAA CATTGTCCTC 
TCAGGAGGTT CTACCCTGTT CAAAGATATC TGCACCCCAG GAGAGACTGT ATTCCACATG 
GATTGGAGGT TCTATCCTTG CTTCCCTGGA CACCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi.
Human molecular genetics19(18)3634-41(2010 Sep)
Clarkson YL,Gillespie T,Perkins EM,Lyndon AR,Jackson M

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)
Werner HB,Kuhlmann K,Shen S,Uecker M,Schardt A,Dimova K,Orfaniotou F,Dhaunchak A,Brinkmann BG,M?bius W,Guarente L,Casaccia-Bonnefil P,Jahn O,Nave KA

PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum.
The Journal of biological chemistry281(32)23003-12(2006 Aug)
Lin SS,Bassik MC,Suh H,Nishino M,Arroyo JD,Hahn WC,Korsmeyer SJ,Roberts TM

Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1.
Molecular biology of the cell14(7)2645-54(2003 Jul)
Eckley DM,Schroer TA

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.
Genome research13(6B)1273-89(2003 Jun)
Carninci P,Waki K,Shiraki T,Konno H,Shibata K,Itoh M,Aizawa K,Arakawa T,Ishii Y,Sasaki D,Bono H,Kondo S,Sugahara Y,Saito R,Osato N,Fukuda S,Sato K,Watahiki A,Hirozane-Kishikawa T,Nakamura M,Shibata Y,Yasunishi A,Kikuchi N,Yoshiki A,Kusakabe M,Gustincich S,Beisel K,Pavan W,Aidinis V,Nakagawara A,Held WA,Iwata H,Kono T,Nakauchi H,Lyons P,Wells C,Hume DA,Fagiolini M,Hensch TK,Brinkmeier M,Camper S,Hirota J,Mombaerts P,Muramatsu M,Okazaki Y,Kawai J,Hayashizaki Y

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Actr1a cDNA ORF clone, Mus musculus(house mouse)

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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