Vti1b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vti1b
Entrez Gene ID	53612
Full Name	vesicle transport through interaction with t-SNAREs 1B
Synonyms	AU015348,GES30,MVti1b,SNARE,Vti1-rp1
General protein information	Preferred Names vesicle transport through interaction with t-SNAREs 1B Names vesicle transport through interaction with t-SNAREs homolog 1B A novel SNARE Soluble N-ethylmaleimide-sensitive factor-attachment protein receptor vesicle transport through interaction with t-SNAREs 1B homolog vesicle transport v-SNARE protein Vti1-like 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12\|12 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_016800.3	NP_058080.2	vesicle transport through interaction with t-SNAREs homolog 1B isoform 1
XM_011244143.1	XP_011242445.1	vesicle transport through interaction with t-SNAREs homolog 1B isoform X1
NM_001364374.1	NP_001351303.1	vesicle transport through interaction with t-SNAREs homolog 1B isoform 2
XM_006516088.3	XP_006516151.1	vesicle transport through interaction with t-SNAREs homolog 1B isoform X1
XM_011244143.2	XP_011242445.1	vesicle transport through interaction with t-SNAREs homolog 1B isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	VTI1B	XP_421192.1
	VTI1B	XP_001107598.1
Canis lupus familiaris (dog)	VTI1B	XP_537489.2
Bos taurus (cattle)	VTI1B	NP_001073115.1
Mus musculus (house mouse)	Vti1b	NP_058080.2
Homo sapiens (human)	VTI1B	NP_006361.1
Rattus norvegicus (Norway rat)	Vti1b	XP_003750244.1
Xenopus tropicalis (tropical clawed frog)	vti1b	NP_001016960.1
Pan troglodytes (chimpanzee)	VTI1B	NP_001238940.1
Danio rerio (zebrafish)	vti1b	NP_957330.1

Gene Ontology
Bibliography

Related articles in PubMed

Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function.
Sardinha VM, Guerra-Gomes S, Caetano I, Tavares G, Martins M, Reis JS, Correia JS, Teixeira-Castro A, Pinto L, Sousa N, Oliveira JF
Glia65(12)1944-1960(2017 Dec)

Suppression of SNARE-dependent exocytosis in retinal glial cells and its effect on ischemia-induced neurodegeneration.
Wagner L, Pannicke T, Rupprecht V, Frommherz I, Volz C, Illes P, Hirrlinger J, J?gle H, Egger V, Haydon PG, Pfrieger FW, Grosche A
Glia65(7)1059-1071(2017 Jul)

A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation.
Wu SJ, Niknafs YS, Kim SH, Oravecz-Wilson K, Zajac C, Toubai T, Sun Y, Prasad J, Peltier D, Fujiwara H, Hedig I, Mathewson ND, Khoriaty R, Ginsburg D, Reddy P
Cell reports19(13)2645-2656(2017 Jun)

Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
Golebiewska EM, Harper MT, Williams CM, Savage JS, Goggs R, Fischer von Mollard G, Poole AW
The Journal of biological chemistry290(3)1536-45(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

syntaxin 1 and vesicle-associated membrane protein 1 are more suitable targets to abolish functional soluble N-ethylmaleimide-sensitive factor attachment protein receptor complexes
Title: Selective cleavage of SNAREs in sensory neurons unveils protein complexes mediating peptide exocytosis triggered by different stimuli.

The dnSNARE mice performed significantly better than littermate controls on rung walk and adhesive dot removal tasks following lesion. and demonistraed that the important role of astrocytic signaling under ischemic conditions.
Title: Inhibition of a SNARE-sensitive pathway in astrocytes attenuates damage following stroke.

These results suggest that SNARE proteins are necessary for the increased activity of KCC2 after Zn(2+) stimulation of mZnR/GPR39.
Title: SNARE-dependent upregulation of potassium chloride co-transporter 2 activity after metabotropic zinc receptor activation in rat cortical neurons in vitro.

Results suggest that by regulating the availability of Vti1b, Stx11 regulates trafficking steps between late endosomes, lysosomes and the cell surface in macrophages.
Title: Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.

The identify IR as the first known tyrosine kinase for Munc18c as in GLUT4 vesicle exocytosis, exemplifying a new model for the coordination of SNARE assembly and vesicle mobilization events in response to a single extracellular stimulus.
Title: Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis.

The following Vti1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vti1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19108	NM_016800.3 Latest version!	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu47998	NM_001364374.1 Latest version!	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu47998	XM_006516088.3 Latest version!	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu47998	XM_011244143.2 Latest version!	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu47998	XM_011244143.1	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vti1b ( NM_016800.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058080.2 Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu19108
Clone ID Related Accession (Same CDS sequence)	NM_016800.3
Accession Version	NM_016800.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 699bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Mus musculus(house mouse)
Product	vesicle transport through interaction with t-SNAREs homolog 1B isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY280269.1, CX239415.1 and BQ177030.1. On Aug 14, 2009 this sequence version replaced NM_016800.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK002289.1, SRR1660819.78009.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCT CCGCCGCCTC CTCCGAGCAT TTCGAGAAGC TGCACGAGAT CTTCCGCGGC 
CTCCTTGAAG ACTTACAAGG GGTGCCGGAG CGGCTGCTGG GGACCGCGGG GACAGAAGAG 
AAGAAGAAGC TGGTCAGAGA TTTTGATGAA AAGCAACAGG AAGCAAATGA AACGTTGGCA 
GAGATGGAGG AAGAACTACG ATATGCACCC CTGACTTTCC GTAACCCCAT GATGTCTAAG 
CTGAGAAACT ACCGGAAGGA CCTTGCTAAA CTCCACCGTG AGGTGAGAAG TACACCTCTG 
ACAGCCGCTC CTGGAGGCCG AGGAGACCTG AAGTATGGCA CGTATACCTT GGAGAACGAG 
CATTTGAATC GACTACAGTC TCAAAGAGCA TTACTCCTAC AAGGCACTGA AAGCCTGAAC 
CGGGCTACCC AAAGCATTGA GCGTTCTCAT CGGATTGCCA CAGAAACTGA TCAAATTGGT 
ACAGAAATCA TAGAAGAGTT GGGGGAGCAA CGAGACCAGT TGGAACGTAC TAAGAGCAGA 
CTGGTAAATA CAAATGAAAA TTTGAGCAAA AGCCGGAAGA TTCTTCGCTC AATGTCCAGA 
AAAGTGATAA CCAACAAGTT GCTGCTCTCC GTCATCATCT TGCTGGAGCT AGCCATCCTG 
GTCGGTCTGG TGTATTACAA ATTCTTTCGA CACCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058080.2
CDS	125..823
Translation	MAASAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDEKQQEANETLAEMEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH

Target ORF information:

RefSeq Version	NM_016800.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016800.3

ORF Insert Sequence:

ATGGCCGCCT CCGCCGCCTC CTCCGAGCAT TTCGAGAAGC TGCACGAGAT CTTCCGCGGC 
CTCCTTGAAG ACTTACAAGG GGTGCCGGAG CGGCTGCTGG GGACCGCGGG GACAGAAGAG 
AAGAAGAAGC TGGTCAGAGA TTTTGATGAA AAGCAACAGG AAGCAAATGA AACGTTGGCA 
GAGATGGAGG AAGAACTACG ATATGCACCC CTGACTTTCC GTAACCCCAT GATGTCTAAG 
CTGAGAAACT ACCGGAAGGA CCTTGCTAAA CTCCACCGTG AGGTGAGAAG TACACCTCTG 
ACAGCCGCTC CTGGAGGCCG AGGAGACCTG AAGTATGGCA CGTATACCTT GGAGAACGAG 
CATTTGAATC GACTACAGTC TCAAAGAGCA TTACTCCTAC AAGGCACTGA AAGCCTGAAC 
CGGGCTACCC AAAGCATTGA GCGTTCTCAT CGGATTGCCA CAGAAACTGA TCAAATTGGT 
ACAGAAATCA TAGAAGAGTT GGGGGAGCAA CGAGACCAGT TGGAACGTAC TAAGAGCAGA 
CTGGTAAATA CAAATGAAAA TTTGAGCAAA AGCCGGAAGA TTCTTCGCTC AATGTCCAGA 
AAAGTGATAA CCAACAAGTT GCTGCTCTCC GTCATCATCT TGCTGGAGCT AGCCATCCTG 
GTCGGTCTGG TGTATTACAA ATTCTTTCGA CACCATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vti1b ( NM_001364374.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001351303.1 Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu47998
Clone ID Related Accession (Same CDS sequence)	XM_011244143.1 , NM_001364374.1 , XM_006516088.3 , XM_011244143.2
Accession Version	NM_001364374.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Mus musculus(house mouse)
Product	vesicle transport through interaction with t-SNAREs homolog 1B isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC154585.2. On Jun 15, 2018 this sequence version replaced XM_006516088.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC002290.1, BI246400.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001351303.1
CDS	249..764
Translation	MEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH

Target ORF information:

RefSeq Version	NM_001364374.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001364374.1

ORF Insert Sequence:

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vti1b ( XM_011244143.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242445.1 Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu47998
Clone ID Related Accession (Same CDS sequence)	XM_011244143.1 , NM_001364374.1 , XM_006516088.3 , XM_011244143.2
Accession Version	XM_011244143.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	vesicle transport through interaction with t-SNAREs homolog 1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011242445.1
CDS	265..780
Translation	MEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH

Target ORF information:

RefSeq Version	XM_011244143.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011244143.1

ORF Insert Sequence:

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vti1b ( XM_006516088.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006516151.1 Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu47998
Clone ID Related Accession (Same CDS sequence)	XM_011244143.1 , NM_001364374.1 , XM_006516088.3 , XM_011244143.2
Accession Version	XM_006516088.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	vesicle transport through interaction with t-SNAREs homolog 1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006516088.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006516151.1
CDS	433..948
Translation	MEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH

Target ORF information:

RefSeq Version	XM_006516088.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006516088.3

ORF Insert Sequence:

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vti1b ( XM_011244143.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011242445.1 Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu47998
Clone ID Related Accession (Same CDS sequence)	XM_011244143.1 , NM_001364374.1 , XM_006516088.3 , XM_011244143.2
Accession Version	XM_011244143.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	vesicle transport through interaction with t-SNAREs homolog 1B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011244143.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011242445.1
CDS	618..1133
Translation	MEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH

Target ORF information:

RefSeq Version	XM_011244143.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus vesicle transport through interaction with t-SNAREs 1B (Vti1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011244143.2

ORF Insert Sequence:

ATGGAGGAAG AACTACGATA TGCACCCCTG ACTTTCCGTA ACCCCATGAT GTCTAAGCTG 
AGAAACTACC GGAAGGACCT TGCTAAACTC CACCGTGAGG TGAGAAGTAC ACCTCTGACA 
GCCGCTCCTG GAGGCCGAGG AGACCTGAAG TATGGCACGT ATACCTTGGA GAACGAGCAT 
TTGAATCGAC TACAGTCTCA AAGAGCATTA CTCCTACAAG GCACTGAAAG CCTGAACCGG 
GCTACCCAAA GCATTGAGCG TTCTCATCGG ATTGCCACAG AAACTGATCA AATTGGTACA 
GAAATCATAG AAGAGTTGGG GGAGCAACGA GACCAGTTGG AACGTACTAA GAGCAGACTG 
GTAAATACAA ATGAAAATTT GAGCAAAAGC CGGAAGATTC TTCGCTCAAT GTCCAGAAAA 
GTGATAACCA ACAAGTTGCT GCTCTCCGTC ATCATCTTGC TGGAGCTAGC CATCCTGGTC 
GGTCTGGTGT ATTACAAATT CTTTCGACAC CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function.
Glia65(12)1944-1960(2017 Dec)
Sardinha VM,Guerra-Gomes S,Caetano I,Tavares G,Martins M,Reis JS,Correia JS,Teixeira-Castro A,Pinto L,Sousa N,Oliveira JF

Suppression of SNARE-dependent exocytosis in retinal glial cells and its effect on ischemia-induced neurodegeneration.
Glia65(7)1059-1071(2017 Jul)
Wagner L,Pannicke T,Rupprecht V,Frommherz I,Volz C,Illes P,Hirrlinger J,J?gle H,Egger V,Haydon PG,Pfrieger FW,Grosche A

A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation.
Cell reports19(13)2645-2656(2017 Jun)
Wu SJ,Niknafs YS,Kim SH,Oravecz-Wilson K,Zajac C,Toubai T,Sun Y,Prasad J,Peltier D,Fujiwara H,Hedig I,Mathewson ND,Khoriaty R,Ginsburg D,Reddy P

Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.
The Journal of biological chemistry290(3)1536-45(2015 Jan)
Golebiewska EM,Harper MT,Williams CM,Savage JS,Goggs R,Fischer von Mollard G,Poole AW

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Vti1b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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