Prdx4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prdx4
Entrez Gene ID	53381
Full Name	peroxiredoxin 4
Synonyms	AOE372,Prx-iv,Prx4,TRANK
General protein information	Preferred Names peroxiredoxin 4 Names peroxiredoxin-4 Prx IV antioxidant enzyme AOE372 peroxiredoxin IV thioredoxin peroxidase AO372 thioredoxin-dependent peroxide reductase A0372
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X F3\|X 72.38 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_016764.5	NP_058044.1	peroxiredoxin-4 isoform 2 precursor
XM_011247844.2	XP_011246146.1	peroxiredoxin-4 isoform X1
NM_001313711.1	NP_001300640.1	peroxiredoxin-4 isoform 1 precursor
XM_011247844.1	XP_011246146.1	peroxiredoxin-4 isoform X1

Pathways from BioSystems

Homologies

	PRDX4	XP_001087492.1
Gallus gallus (chicken)	PRDX4	XP_416800.2
Drosophila melanogaster (fruit fly)	Jafrac2	NP_001261350.1
Anopheles gambiae (African malaria mosquito)	TPX3	XP_308336.4
Homo sapiens (human)	PRDX4	NP_006397.1
Bos taurus (cattle)	PRDX4	NP_776858.1
Mus musculus (house mouse)	Prdx4	NP_058044.1
Danio rerio (zebrafish)	prdx4	NP_001082894.1
Xenopus tropicalis (tropical clawed frog)	prdx4	NP_001006812.1
Canis lupus familiaris (dog)	PRDX4	XP_003640291.1
Rattus norvegicus (Norway rat)	Prdx4	NP_445964.1

Gene Ontology
Bibliography

Related articles in PubMed

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
Wu Y, Wei FY, Kawarada L, Suzuki T, Araki K, Komohara Y, Fujimura A, Kaitsuka T, Takeya M, Oike Y, Suzuki T, Tomizawa K
PLoS genetics12(9)e1006355(2016 Sep)

Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.
Nawata A, Noguchi H, Mazaki Y, Kurahashi T, Izumi H, Wang KY, Guo X, Uramoto H, Kohno K, Taniguchi H, Tanaka Y, Fujii J, Sasaguri Y, Tanimoto A, Nakayama T, Yamada S
PloS one11(4)e0152549(2016)

Implication of Differential Peroxiredoxin 4 Expression with Age in Ovaries of Mouse and Human for Ovarian Aging.
Qian Y, Shao L, Yuan C, Jiang CY, Liu J, Gao C, Gao L, Cui YG, Jiang SW, Liu JY, Meng Y
Current molecular medicine16(3)243-51(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data provide the first evidence of the beneficial effects of PRDX4 on intestinal function in the reduction of the severity of NAFLD, by ameliorating oxidative stress-induced local and systemic injury
Title: Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.

Prdx4 expression was closely related to follicular development and has aprominent role in protecting human and mouse granulosa cells from reactive oxygen species damage.
Title: Implication of Differential Peroxiredoxin 4 Expression with Age in Ovaries of Mouse and Human for Ovarian Aging.

The ventral signal observed for Prdx4 from early stages colocalized with motor neuron markers Isl1/2 and FoxP1 and the strong ventral signal colocalizing with Isl1/2 was observed in all rostrocaudal segments of the spinal cord.
Title: Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development.

Prdx4 dimers generated by hydrogen peroxide metabolism oxidize two cysteine residues within the GDE2 enzymatic domain, which blocks GDE2 trafficking to the plasma membrane and prevents GDE2 neurogeneic function.
Title: Prdx4 is a compartment-specific H2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2.

PRDX4 may protect against nonalcoholic steatohepatitis and type 2 diabetes by ameliorating oxidative stress-induced injury.
Title: Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model.

The following Prdx4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prdx4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu69482	NM_001313711.1 Latest version!	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu10672	NM_016764.5 Latest version!	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu69483	XM_011247844.2 Latest version!	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu69483	XM_011247844.1	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prdx4 ( NM_001313711.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001300640.1 Mus musculus peroxiredoxin 4 (Prdx4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu69482
Clone ID Related Accession (Same CDS sequence)	NM_001313711.1
Accession Version	NM_001313711.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 828bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	peroxiredoxin-4 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ079814.1, AK152255.1 and AW121558.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU512775.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCGC GGTCCAAGCT GCTGGACGGG ACCACGGCGT CCCGTCGCTG GACCCGAAAG 
CTGGTGTTGC TCCTGCCGCC GCTGCTGCTG TTCCTGTTGC GGACCGAATC TCTGCAAGGC 
TTGGAGAGTG ATGAACGGTT CCGGACCCGC GAAAATGAGT GCCACTTCTA CGCTGGTGGA 
CAAGTGTACC CCGGGGAGGC GTCCCGGGTT TCAGTCGCGG ATCACTCCCT GCATCTAAGC 
AAAGCCAAGA TCTCCAAGCC AGCACCTTAT TGGGAAGGAA CAGCTGTGAT TAACGGAGAA 
TTCAAGGAGC TCAAACTGAC TGACTATCGT GGGAAATACT TGGTTTTTTT CTTCTACCCA 
CTGGATTTCA CCTTTGTGTG TCCAACTGAA ATCATCGCTT TTGGGGATCG AATTGAAGAA 
TTCAAATCTA TAAATACTGA AGTGGTAGCA TGCTCTGTTG ACTCTCAGTT TACCCACTTG 
GCCTGGATTA ATACCCCTCG AAGACAAGGA GGACTGGGGC CAATAAGGAT TCCACTTCTT 
TCTGACCTGA ACCATCAGAT CTCAAAGGAC TATGGTGTAT ACCTTGAAGA CTCAGGACAT 
ACTCTTAGAG GCCTCTTTAT TATCGATGAC AAAGGAGTCC TGAGGCAGAT TACTCTGAAT 
GACCTTCCTG TCGGAAGATC AGTGGACGAG ACACTGCGTT TGGTTCAAGC CTTCCAGTAC 
ACTGACAAGC ATGGAGAAGA TAATCCCAGA TCCAGCTGGA AAACTGAAGT ATTTCGACAA 
GCTAAACTGA AAAGTACTTC AGTTATGATG TTTGGACCTT CTCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001300640.1
CDS	99..926
Translation	MEARSKLLDGTTASRRWTRKLVLLLPPLLLFLLRTESLQGLESDERFRTRENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWKTEVFRQAKLKSTSVMMFGPSQ

Target ORF information:

RefSeq Version	NM_001313711.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001313711.1

ORF Insert Sequence:

ATGGAGGCGC GGTCCAAGCT GCTGGACGGG ACCACGGCGT CCCGTCGCTG GACCCGAAAG 
CTGGTGTTGC TCCTGCCGCC GCTGCTGCTG TTCCTGTTGC GGACCGAATC TCTGCAAGGC 
TTGGAGAGTG ATGAACGGTT CCGGACCCGC GAAAATGAGT GCCACTTCTA CGCTGGTGGA 
CAAGTGTACC CCGGGGAGGC GTCCCGGGTT TCAGTCGCGG ATCACTCCCT GCATCTAAGC 
AAAGCCAAGA TCTCCAAGCC AGCACCTTAT TGGGAAGGAA CAGCTGTGAT TAACGGAGAA 
TTCAAGGAGC TCAAACTGAC TGACTATCGT GGGAAATACT TGGTTTTTTT CTTCTACCCA 
CTGGATTTCA CCTTTGTGTG TCCAACTGAA ATCATCGCTT TTGGGGATCG AATTGAAGAA 
TTCAAATCTA TAAATACTGA AGTGGTAGCA TGCTCTGTTG ACTCTCAGTT TACCCACTTG 
GCCTGGATTA ATACCCCTCG AAGACAAGGA GGACTGGGGC CAATAAGGAT TCCACTTCTT 
TCTGACCTGA ACCATCAGAT CTCAAAGGAC TATGGTGTAT ACCTTGAAGA CTCAGGACAT 
ACTCTTAGAG GCCTCTTTAT TATCGATGAC AAAGGAGTCC TGAGGCAGAT TACTCTGAAT 
GACCTTCCTG TCGGAAGATC AGTGGACGAG ACACTGCGTT TGGTTCAAGC CTTCCAGTAC 
ACTGACAAGC ATGGAGAAGA TAATCCCAGA TCCAGCTGGA AAACTGAAGT ATTTCGACAA 
GCTAAACTGA AAAGTACTTC AGTTATGATG TTTGGACCTT CTCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prdx4 ( XM_011247844.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246146.1 Mus musculus peroxiredoxin 4 (Prdx4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69483
Clone ID Related Accession (Same CDS sequence)	XM_011247844.2 , XM_011247844.1
Accession Version	XM_011247844.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	peroxiredoxin-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCACC GTTGCCGTTC ACGTGGCATG AGCCACAGTC GAGTCTCTGG ATCTCATATC 
CGAACTCCCA GGGTCCCACT TCCGTTCCAT GTTGAGCAGG AGGCTAGGGA AGGAGAAGAA 
TGGGAACGAG AGCTACCTCG TCAGAGGCCT ATCATCTACG GACCTCCAGA AAGCGAAGAG 
TTACAGGAAA CTGTAATGAT CTCCAAGCCA GCACCTTATT GGGAAGGAAC AGCTGTGATT 
AACGGAGAAT TCAAGGAGCT CAAACTGACT GACTATCGTG GGAAATACTT GGTTTTTTTC 
TTCTACCCAC TGGATTTCAC CTTTGTGTGT CCAACTGAAA TCATCGCTTT TGGGGATCGA 
ATTGAAGAAT TCAAATCTAT AAATACTGAA GTGGTAGCAT GCTCTGTTGA CTCTCAGTTT 
ACCCACTTGG CCTGGATTAA TACCCCTCGA AGACAAGGAG GACTGGGGCC AATAAGGATT 
CCACTTCTTT CTGACCTGAA CCATCAGATC TCAAAGGACT ATGGTGTATA CCTTGAAGAC 
TCAGGACATA CTCTTAGAGG CCTCTTTATT ATCGATGACA AAGGAGTCCT GAGGCAGATT 
ACTCTGAATG ACCTTCCTGT CGGAAGATCA GTGGACGAGA CACTGCGTTT GGTTCAAGCC 
TTCCAGTACA CTGACAAGCA TGGAGAAGTC TGCCCTGCTG GCTGGAAACC TGGTAGTGAA 
ACAATAATCC CAGATCCAGC TGGAAAACTG AAGTATTTCG ACAAGCTAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246146.1
CDS	243..1016
Translation	MDHRCRSRGMSHSRVSGSHIRTPRVPLPFHVEQEAREGEEWERELPRQRPIIYGPPESEELQETVMISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN

Target ORF information:

RefSeq Version	XM_011247844.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247844.1

ORF Insert Sequence:

ATGGATCACC GTTGCCGTTC ACGTGGCATG AGCCACAGTC GAGTCTCTGG ATCTCATATC 
CGAACTCCCA GGGTCCCACT TCCGTTCCAT GTTGAGCAGG AGGCTAGGGA AGGAGAAGAA 
TGGGAACGAG AGCTACCTCG TCAGAGGCCT ATCATCTACG GACCTCCAGA AAGCGAAGAG 
TTACAGGAAA CTGTAATGAT CTCCAAGCCA GCACCTTATT GGGAAGGAAC AGCTGTGATT 
AACGGAGAAT TCAAGGAGCT CAAACTGACT GACTATCGTG GGAAATACTT GGTTTTTTTC 
TTCTACCCAC TGGATTTCAC CTTTGTGTGT CCAACTGAAA TCATCGCTTT TGGGGATCGA 
ATTGAAGAAT TCAAATCTAT AAATACTGAA GTGGTAGCAT GCTCTGTTGA CTCTCAGTTT 
ACCCACTTGG CCTGGATTAA TACCCCTCGA AGACAAGGAG GACTGGGGCC AATAAGGATT 
CCACTTCTTT CTGACCTGAA CCATCAGATC TCAAAGGACT ATGGTGTATA CCTTGAAGAC 
TCAGGACATA CTCTTAGAGG CCTCTTTATT ATCGATGACA AAGGAGTCCT GAGGCAGATT 
ACTCTGAATG ACCTTCCTGT CGGAAGATCA GTGGACGAGA CACTGCGTTT GGTTCAAGCC 
TTCCAGTACA CTGACAAGCA TGGAGAAGTC TGCCCTGCTG GCTGGAAACC TGGTAGTGAA 
ACAATAATCC CAGATCCAGC TGGAAAACTG AAGTATTTCG ACAAGCTAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prdx4 ( NM_016764.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058044.1 Mus musculus peroxiredoxin 4 (Prdx4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu10672
Clone ID Related Accession (Same CDS sequence)	NM_016764.5
Accession Version	NM_016764.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	peroxiredoxin-4 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ079814.1, AK152255.1 and AW121558.1. On Aug 27, 2015 this sequence version replaced NM_016764.4. Transcript Variant: This variant (2) lacks contains an alternate exon in the 3' coding region compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC019578.1, U96746.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCGC GGTCCAAGCT GCTGGACGGG ACCACGGCGT CCCGTCGCTG GACCCGAAAG 
CTGGTGTTGC TCCTGCCGCC GCTGCTGCTG TTCCTGTTGC GGACCGAATC TCTGCAAGGC 
TTGGAGAGTG ATGAACGGTT CCGGACCCGC GAAAATGAGT GCCACTTCTA CGCTGGTGGA 
CAAGTGTACC CCGGGGAGGC GTCCCGGGTT TCAGTCGCGG ATCACTCCCT GCATCTAAGC 
AAAGCCAAGA TCTCCAAGCC AGCACCTTAT TGGGAAGGAA CAGCTGTGAT TAACGGAGAA 
TTCAAGGAGC TCAAACTGAC TGACTATCGT GGGAAATACT TGGTTTTTTT CTTCTACCCA 
CTGGATTTCA CCTTTGTGTG TCCAACTGAA ATCATCGCTT TTGGGGATCG AATTGAAGAA 
TTCAAATCTA TAAATACTGA AGTGGTAGCA TGCTCTGTTG ACTCTCAGTT TACCCACTTG 
GCCTGGATTA ATACCCCTCG AAGACAAGGA GGACTGGGGC CAATAAGGAT TCCACTTCTT 
TCTGACCTGA ACCATCAGAT CTCAAAGGAC TATGGTGTAT ACCTTGAAGA CTCAGGACAT 
ACTCTTAGAG GCCTCTTTAT TATCGATGAC AAAGGAGTCC TGAGGCAGAT TACTCTGAAT 
GACCTTCCTG TCGGAAGATC AGTGGACGAG ACACTGCGTT TGGTTCAAGC CTTCCAGTAC 
ACTGACAAGC ATGGAGAAGT CTGCCCTGCT GGCTGGAAAC CTGGTAGTGA AACAATAATC 
CCAGATCCAG CTGGAAAACT GAAGTATTTC GACAAGCTAA ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058044.1
CDS	99..923
Translation	MEARSKLLDGTTASRRWTRKLVLLLPPLLLFLLRTESLQGLESDERFRTRENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN

Target ORF information:

RefSeq Version	NM_016764.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016764.5

ORF Insert Sequence:

ATGGAGGCGC GGTCCAAGCT GCTGGACGGG ACCACGGCGT CCCGTCGCTG GACCCGAAAG 
CTGGTGTTGC TCCTGCCGCC GCTGCTGCTG TTCCTGTTGC GGACCGAATC TCTGCAAGGC 
TTGGAGAGTG ATGAACGGTT CCGGACCCGC GAAAATGAGT GCCACTTCTA CGCTGGTGGA 
CAAGTGTACC CCGGGGAGGC GTCCCGGGTT TCAGTCGCGG ATCACTCCCT GCATCTAAGC 
AAAGCCAAGA TCTCCAAGCC AGCACCTTAT TGGGAAGGAA CAGCTGTGAT TAACGGAGAA 
TTCAAGGAGC TCAAACTGAC TGACTATCGT GGGAAATACT TGGTTTTTTT CTTCTACCCA 
CTGGATTTCA CCTTTGTGTG TCCAACTGAA ATCATCGCTT TTGGGGATCG AATTGAAGAA 
TTCAAATCTA TAAATACTGA AGTGGTAGCA TGCTCTGTTG ACTCTCAGTT TACCCACTTG 
GCCTGGATTA ATACCCCTCG AAGACAAGGA GGACTGGGGC CAATAAGGAT TCCACTTCTT 
TCTGACCTGA ACCATCAGAT CTCAAAGGAC TATGGTGTAT ACCTTGAAGA CTCAGGACAT 
ACTCTTAGAG GCCTCTTTAT TATCGATGAC AAAGGAGTCC TGAGGCAGAT TACTCTGAAT 
GACCTTCCTG TCGGAAGATC AGTGGACGAG ACACTGCGTT TGGTTCAAGC CTTCCAGTAC 
ACTGACAAGC ATGGAGAAGT CTGCCCTGCT GGCTGGAAAC CTGGTAGTGA AACAATAATC 
CCAGATCCAG CTGGAAAACT GAAGTATTTC GACAAGCTAA ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prdx4 ( XM_011247844.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246146.1 Mus musculus peroxiredoxin 4 (Prdx4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69483
Clone ID Related Accession (Same CDS sequence)	XM_011247844.2 , XM_011247844.1
Accession Version	XM_011247844.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	peroxiredoxin-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011247844.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCACC GTTGCCGTTC ACGTGGCATG AGCCACAGTC GAGTCTCTGG ATCTCATATC 
CGAACTCCCA GGGTCCCACT TCCGTTCCAT GTTGAGCAGG AGGCTAGGGA AGGAGAAGAA 
TGGGAACGAG AGCTACCTCG TCAGAGGCCT ATCATCTACG GACCTCCAGA AAGCGAAGAG 
TTACAGGAAA CTGTAATGAT CTCCAAGCCA GCACCTTATT GGGAAGGAAC AGCTGTGATT 
AACGGAGAAT TCAAGGAGCT CAAACTGACT GACTATCGTG GGAAATACTT GGTTTTTTTC 
TTCTACCCAC TGGATTTCAC CTTTGTGTGT CCAACTGAAA TCATCGCTTT TGGGGATCGA 
ATTGAAGAAT TCAAATCTAT AAATACTGAA GTGGTAGCAT GCTCTGTTGA CTCTCAGTTT 
ACCCACTTGG CCTGGATTAA TACCCCTCGA AGACAAGGAG GACTGGGGCC AATAAGGATT 
CCACTTCTTT CTGACCTGAA CCATCAGATC TCAAAGGACT ATGGTGTATA CCTTGAAGAC 
TCAGGACATA CTCTTAGAGG CCTCTTTATT ATCGATGACA AAGGAGTCCT GAGGCAGATT 
ACTCTGAATG ACCTTCCTGT CGGAAGATCA GTGGACGAGA CACTGCGTTT GGTTCAAGCC 
TTCCAGTACA CTGACAAGCA TGGAGAAGTC TGCCCTGCTG GCTGGAAACC TGGTAGTGAA 
ACAATAATCC CAGATCCAGC TGGAAAACTG AAGTATTTCG ACAAGCTAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246146.1
CDS	1766..2539
Translation	MDHRCRSRGMSHSRVSGSHIRTPRVPLPFHVEQEAREGEEWERELPRQRPIIYGPPESEELQETVMISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN

Target ORF information:

RefSeq Version	XM_011247844.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus peroxiredoxin 4 (Prdx4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011247844.2

ORF Insert Sequence:

ATGGATCACC GTTGCCGTTC ACGTGGCATG AGCCACAGTC GAGTCTCTGG ATCTCATATC 
CGAACTCCCA GGGTCCCACT TCCGTTCCAT GTTGAGCAGG AGGCTAGGGA AGGAGAAGAA 
TGGGAACGAG AGCTACCTCG TCAGAGGCCT ATCATCTACG GACCTCCAGA AAGCGAAGAG 
TTACAGGAAA CTGTAATGAT CTCCAAGCCA GCACCTTATT GGGAAGGAAC AGCTGTGATT 
AACGGAGAAT TCAAGGAGCT CAAACTGACT GACTATCGTG GGAAATACTT GGTTTTTTTC 
TTCTACCCAC TGGATTTCAC CTTTGTGTGT CCAACTGAAA TCATCGCTTT TGGGGATCGA 
ATTGAAGAAT TCAAATCTAT AAATACTGAA GTGGTAGCAT GCTCTGTTGA CTCTCAGTTT 
ACCCACTTGG CCTGGATTAA TACCCCTCGA AGACAAGGAG GACTGGGGCC AATAAGGATT 
CCACTTCTTT CTGACCTGAA CCATCAGATC TCAAAGGACT ATGGTGTATA CCTTGAAGAC 
TCAGGACATA CTCTTAGAGG CCTCTTTATT ATCGATGACA AAGGAGTCCT GAGGCAGATT 
ACTCTGAATG ACCTTCCTGT CGGAAGATCA GTGGACGAGA CACTGCGTTT GGTTCAAGCC 
TTCCAGTACA CTGACAAGCA TGGAGAAGTC TGCCCTGCTG GCTGGAAACC TGGTAGTGAA 
ACAATAATCC CAGATCCAGC TGGAAAACTG AAGTATTTCG ACAAGCTAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.
PLoS genetics12(9)e1006355(2016 Sep)
Wu Y,Wei FY,Kawarada L,Suzuki T,Araki K,Komohara Y,Fujimura A,Kaitsuka T,Takeya M,Oike Y,Suzuki T,Tomizawa K

Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.
PloS one11(4)e0152549(2016)
Nawata A,Noguchi H,Mazaki Y,Kurahashi T,Izumi H,Wang KY,Guo X,Uramoto H,Kohno K,Taniguchi H,Tanaka Y,Fujii J,Sasaguri Y,Tanimoto A,Nakayama T,Yamada S

Implication of Differential Peroxiredoxin 4 Expression with Age in Ovaries of Mouse and Human for Ovarian Aging.
Current molecular medicine16(3)243-51(2016)
Qian Y,Shao L,Yuan C,Jiang CY,Liu J,Gao C,Gao L,Cui YG,Jiang SW,Liu JY,Meng Y

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Prdx4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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