Sdcbp cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sdcbp
Entrez Gene ID	53378
Full Name	syndecan binding protein
Synonyms	MDA-9,Sycl,syntenin-1
General protein information	Preferred Names syndecan binding protein Names syntenin-1 scaffold protein Pbp1 syndecan interacting protein syndecan-binding protein 1 syntenin
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4\|4 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_016807.2	NP_058087.2	syntenin-1 isoform 2
XM_006538084.4	XP_006538147.1	syntenin-1 isoform X1
XM_006538084.3	XP_006538147.1	syntenin-1 isoform X1
XM_030253672.1	XP_030109532.1	syntenin-1 isoform X2
NM_001098227.1	NP_001091697.1	syntenin-1 isoform 1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009569	XP_318581.1
Pan troglodytes (chimpanzee)	SDCBP	NP_001233375.1
	SDCBP	XP_001088209.2
Homo sapiens (human)	SDCBP	NP_005616.2
Rattus norvegicus (Norway rat)	Sdcbp	NP_114192.1
Gallus gallus (chicken)	SDCBP	NP_001026195.1
Canis lupus familiaris (dog)	SDCBP	XP_005638059.1
Bos taurus (cattle)	SDCBP	NP_001068951.1
Mus musculus (house mouse)	Sdcbp	NP_001091697.1
Danio rerio (zebrafish)	sdcbp	NP_997856.1
Xenopus tropicalis (tropical clawed frog)	sdcbp	NP_001006801.1

Gene Ontology
Bibliography

Related articles in PubMed

Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells.
Tae N, Lee S, Kim O, Park J, Na S, Lee JH
Oncotarget8(24)38886-38901(2017 Jun)

Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
Das SK, Guo C, Pradhan AK, Bhoopathi P, Talukdar S, Shen XN, Emdad L, Subler MA, Windle JJ, Sarkar D, Wang XY, Fisher PB
Oncotarget7(30)46848-46861(2016 Jul)

Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.
Sugiura H, Yasuda S, Katsurabayashi S, Kawano H, Endo K, Takasaki K, Iwasaki K, Ichikawa M, Kobayashi T, Hino O, Yamagata K
Nature communications66842(2015 Apr)

Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells.
Kashyap R, Roucourt B, Lembo F, Fares J, Carcavilla AM, Restouin A, Zimmermann P, Ghossoub R
Frontiers in pharmacology6241(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Present study is the first demonstration of the relevance of MDA-9/Syntenin expression in regulating inflammation and immunosuppression in the microenvironment thereby impacting tumor growth and metastasis in mouse melanoma model.
Title: Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.

Syntenin-1 negatively regulates the intestinal immunoglobulin production and has a function to maintain the intestinal homeostasis in vivo.
Title: Increased production of intestinal immunoglobulins in Syntenin-1-deficient mice.

ALCAM stably interacts with actin by binding to syntenin-1 and ezrin.
Title: Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton.

Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.
Title: Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.

MDA-9/syntenin may play a prominent role during normal mouse development in the context of cell proliferation as well as differentiation through modulating multiple signaling pathways as a crucial adaptor protein.
Title: Expression patterns of MDA-9/syntenin during development of the mouse embryo.

The following Sdcbp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sdcbp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu18620	NM_016807.2 Latest version!	Mus musculus syndecan binding protein (Sdcbp), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu18862	NM_001098227.1 Latest version!	Mus musculus syndecan binding protein (Sdcbp), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu18620	XM_030253672.1 Latest version!	Mus musculus syndecan binding protein (Sdcbp), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu18862	XM_006538084.4 Latest version!	Mus musculus syndecan binding protein (Sdcbp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu18862	XM_006538084.3	Mus musculus syndecan binding protein (Sdcbp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sdcbp ( NM_016807.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058087.2 Mus musculus syndecan binding protein (Sdcbp), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu18620
Clone ID Related Accession (Same CDS sequence)	NM_016807.2 , XM_030253672.1
Accession Version	NM_016807.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Mus musculus(house mouse)
Product	syntenin-1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY779386.1, AK150278.1, BY757323.1, W65143.1, BB736053.1 and BY387130.1. On May 24, 2007 this sequence version replaced NM_016807.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660821.165420.1, SRR1660811.44228.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGTTGGTAG CAAGACCATC CAGTGTGAAC TATATGGTAG CACCTGTGAC AGGTAACGAT 
GCTGGAATTC GGAGAGCAGA AATTAAGCAA GGGATCCGTG AAGTTATTTT GTGTAAGGAT 
CAAGATGGAA AAATTGGGCT CAGACTTAAG TCAATAGATA ATGGTATATT TGTTCAACTC 
GTCCAGGCTA ATTCCCCAGC CTCCTTGGTT GGACTGAGAT TTGGGGACCA GGTGCTCCAG 
ATCAACGGTG AAAACTGTGC GGGCTGGAGC TCTGATAAGG CACACAAGGT GCTCAAGCAG 
GCGTTTGGAG AGAAGATCAC CATGACGATC CGTGACAGGC CCTTTGAACG GACAGTTACT 
ATGCATAAGG ACAGCAGTGG ACATGTTGGC TTTATCTTTA AAAGTGGAAA AATCACATCC 
ATAGTAAAAG ATAGTTCTGC TGCCAGAAAC GGCCTCCTCA CTGATCACCA CATCTGTGAG 
ATCAACGGAC AGAACGTCAT TGGCTTGAAG GATGCTCAGA TTGCAGATAT ACTGTCAACA 
GCTGGGACTG TGGTTACCAT CACAATCATG CCTACTTTTA TCTTCGAACA CATTATTAAA 
CGGATGGCTC CCAGCATTAT GAAAAGCCTG ATGGATCACA CCATTCCTGA AGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058087.2
CDS	96..992
Translation	MSLYPSLEDLKVDKVIQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSLNEAEICESMPMVSGAPAQGLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDHTIPEV

Target ORF information:

RefSeq Version	NM_016807.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus syndecan binding protein (Sdcbp), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016807.2

ORF Insert Sequence:

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGTTGGTAG CAAGACCATC CAGTGTGAAC TATATGGTAG CACCTGTGAC AGGTAACGAT 
GCTGGAATTC GGAGAGCAGA AATTAAGCAA GGGATCCGTG AAGTTATTTT GTGTAAGGAT 
CAAGATGGAA AAATTGGGCT CAGACTTAAG TCAATAGATA ATGGTATATT TGTTCAACTC 
GTCCAGGCTA ATTCCCCAGC CTCCTTGGTT GGACTGAGAT TTGGGGACCA GGTGCTCCAG 
ATCAACGGTG AAAACTGTGC GGGCTGGAGC TCTGATAAGG CACACAAGGT GCTCAAGCAG 
GCGTTTGGAG AGAAGATCAC CATGACGATC CGTGACAGGC CCTTTGAACG GACAGTTACT 
ATGCATAAGG ACAGCAGTGG ACATGTTGGC TTTATCTTTA AAAGTGGAAA AATCACATCC 
ATAGTAAAAG ATAGTTCTGC TGCCAGAAAC GGCCTCCTCA CTGATCACCA CATCTGTGAG 
ATCAACGGAC AGAACGTCAT TGGCTTGAAG GATGCTCAGA TTGCAGATAT ACTGTCAACA 
GCTGGGACTG TGGTTACCAT CACAATCATG CCTACTTTTA TCTTCGAACA CATTATTAAA 
CGGATGGCTC CCAGCATTAT GAAAAGCCTG ATGGATCACA CCATTCCTGA AGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sdcbp ( NM_001098227.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001091697.1 Mus musculus syndecan binding protein (Sdcbp), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu18862
Clone ID Related Accession (Same CDS sequence)	XM_006538084.4 , XM_006538084.3 , NM_001098227.1
Accession Version	NM_001098227.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	syntenin-1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY779386.1, AK150278.1, BY757323.1, W65143.1, BB736053.1 and BY387130.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK028429.1, AK033412.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGCAGTTGG TAGCAAGACC ATCCAGTGTG AACTATATGG TAGCACCTGT GACAGGTAAC 
GATGCTGGAA TTCGGAGAGC AGAAATTAAG CAAGGGATCC GTGAAGTTAT TTTGTGTAAG 
GATCAAGATG GAAAAATTGG GCTCAGACTT AAGTCAATAG ATAATGGTAT ATTTGTTCAA 
CTCGTCCAGG CTAATTCCCC AGCCTCCTTG GTTGGACTGA GATTTGGGGA CCAGGTGCTC 
CAGATCAACG GTGAAAACTG TGCGGGCTGG AGCTCTGATA AGGCACACAA GGTGCTCAAG 
CAGGCGTTTG GAGAGAAGAT CACCATGACG ATCCGTGACA GGCCCTTTGA ACGGACAGTT 
ACTATGCATA AGGACAGCAG TGGACATGTT GGCTTTATCT TTAAAAGTGG AAAAATCACA 
TCCATAGTAA AAGATAGTTC TGCTGCCAGA AACGGCCTCC TCACTGATCA CCACATCTGT 
GAGATCAACG GACAGAACGT CATTGGCTTG AAGGATGCTC AGATTGCAGA TATACTGTCA 
ACAGCTGGGA CTGTGGTTAC CATCACAATC ATGCCTACTT TTATCTTCGA ACACATTATT 
AAACGGATGG CTCCCAGCAT TATGAAAAGC CTGATGGATC ACACCATTCC TGAAGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091697.1
CDS	96..995
Translation	MSLYPSLEDLKVDKVIQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSLNEAEICESMPMVSGAPAQGQLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDHTIPEV

Target ORF information:

RefSeq Version	NM_001098227.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syndecan binding protein (Sdcbp), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098227.1

ORF Insert Sequence:

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGCAGTTGG TAGCAAGACC ATCCAGTGTG AACTATATGG TAGCACCTGT GACAGGTAAC 
GATGCTGGAA TTCGGAGAGC AGAAATTAAG CAAGGGATCC GTGAAGTTAT TTTGTGTAAG 
GATCAAGATG GAAAAATTGG GCTCAGACTT AAGTCAATAG ATAATGGTAT ATTTGTTCAA 
CTCGTCCAGG CTAATTCCCC AGCCTCCTTG GTTGGACTGA GATTTGGGGA CCAGGTGCTC 
CAGATCAACG GTGAAAACTG TGCGGGCTGG AGCTCTGATA AGGCACACAA GGTGCTCAAG 
CAGGCGTTTG GAGAGAAGAT CACCATGACG ATCCGTGACA GGCCCTTTGA ACGGACAGTT 
ACTATGCATA AGGACAGCAG TGGACATGTT GGCTTTATCT TTAAAAGTGG AAAAATCACA 
TCCATAGTAA AAGATAGTTC TGCTGCCAGA AACGGCCTCC TCACTGATCA CCACATCTGT 
GAGATCAACG GACAGAACGT CATTGGCTTG AAGGATGCTC AGATTGCAGA TATACTGTCA 
ACAGCTGGGA CTGTGGTTAC CATCACAATC ATGCCTACTT TTATCTTCGA ACACATTATT 
AAACGGATGG CTCCCAGCAT TATGAAAAGC CTGATGGATC ACACCATTCC TGAAGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sdcbp ( XM_006538084.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538147.1 Mus musculus syndecan binding protein (Sdcbp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu18862
Clone ID Related Accession (Same CDS sequence)	XM_006538084.4 , XM_006538084.3 , NM_001098227.1
Accession Version	XM_006538084.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	syntenin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006538084.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGCAGTTGG TAGCAAGACC ATCCAGTGTG AACTATATGG TAGCACCTGT GACAGGTAAC 
GATGCTGGAA TTCGGAGAGC AGAAATTAAG CAAGGGATCC GTGAAGTTAT TTTGTGTAAG 
GATCAAGATG GAAAAATTGG GCTCAGACTT AAGTCAATAG ATAATGGTAT ATTTGTTCAA 
CTCGTCCAGG CTAATTCCCC AGCCTCCTTG GTTGGACTGA GATTTGGGGA CCAGGTGCTC 
CAGATCAACG GTGAAAACTG TGCGGGCTGG AGCTCTGATA AGGCACACAA GGTGCTCAAG 
CAGGCGTTTG GAGAGAAGAT CACCATGACG ATCCGTGACA GGCCCTTTGA ACGGACAGTT 
ACTATGCATA AGGACAGCAG TGGACATGTT GGCTTTATCT TTAAAAGTGG AAAAATCACA 
TCCATAGTAA AAGATAGTTC TGCTGCCAGA AACGGCCTCC TCACTGATCA CCACATCTGT 
GAGATCAACG GACAGAACGT CATTGGCTTG AAGGATGCTC AGATTGCAGA TATACTGTCA 
ACAGCTGGGA CTGTGGTTAC CATCACAATC ATGCCTACTT TTATCTTCGA ACACATTATT 
AAACGGATGG CTCCCAGCAT TATGAAAAGC CTGATGGATC ACACCATTCC TGAAGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538147.1
CDS	224..1123
Translation	MSLYPSLEDLKVDKVIQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSLNEAEICESMPMVSGAPAQGQLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDHTIPEV

Target ORF information:

RefSeq Version	XM_006538084.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus syndecan binding protein (Sdcbp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538084.3

ORF Insert Sequence:

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGCAGTTGG TAGCAAGACC ATCCAGTGTG AACTATATGG TAGCACCTGT GACAGGTAAC 
GATGCTGGAA TTCGGAGAGC AGAAATTAAG CAAGGGATCC GTGAAGTTAT TTTGTGTAAG 
GATCAAGATG GAAAAATTGG GCTCAGACTT AAGTCAATAG ATAATGGTAT ATTTGTTCAA 
CTCGTCCAGG CTAATTCCCC AGCCTCCTTG GTTGGACTGA GATTTGGGGA CCAGGTGCTC 
CAGATCAACG GTGAAAACTG TGCGGGCTGG AGCTCTGATA AGGCACACAA GGTGCTCAAG 
CAGGCGTTTG GAGAGAAGAT CACCATGACG ATCCGTGACA GGCCCTTTGA ACGGACAGTT 
ACTATGCATA AGGACAGCAG TGGACATGTT GGCTTTATCT TTAAAAGTGG AAAAATCACA 
TCCATAGTAA AAGATAGTTC TGCTGCCAGA AACGGCCTCC TCACTGATCA CCACATCTGT 
GAGATCAACG GACAGAACGT CATTGGCTTG AAGGATGCTC AGATTGCAGA TATACTGTCA 
ACAGCTGGGA CTGTGGTTAC CATCACAATC ATGCCTACTT TTATCTTCGA ACACATTATT 
AAACGGATGG CTCCCAGCAT TATGAAAAGC CTGATGGATC ACACCATTCC TGAAGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sdcbp ( XM_030253672.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030109532.1 Mus musculus syndecan binding protein (Sdcbp), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu18620
Clone ID Related Accession (Same CDS sequence)	NM_016807.2 , XM_030253672.1
Accession Version	XM_030253672.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	syntenin-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGTTGGTAG CAAGACCATC CAGTGTGAAC TATATGGTAG CACCTGTGAC AGGTAACGAT 
GCTGGAATTC GGAGAGCAGA AATTAAGCAA GGGATCCGTG AAGTTATTTT GTGTAAGGAT 
CAAGATGGAA AAATTGGGCT CAGACTTAAG TCAATAGATA ATGGTATATT TGTTCAACTC 
GTCCAGGCTA ATTCCCCAGC CTCCTTGGTT GGACTGAGAT TTGGGGACCA GGTGCTCCAG 
ATCAACGGTG AAAACTGTGC GGGCTGGAGC TCTGATAAGG CACACAAGGT GCTCAAGCAG 
GCGTTTGGAG AGAAGATCAC CATGACGATC CGTGACAGGC CCTTTGAACG GACAGTTACT 
ATGCATAAGG ACAGCAGTGG ACATGTTGGC TTTATCTTTA AAAGTGGAAA AATCACATCC 
ATAGTAAAAG ATAGTTCTGC TGCCAGAAAC GGCCTCCTCA CTGATCACCA CATCTGTGAG 
ATCAACGGAC AGAACGTCAT TGGCTTGAAG GATGCTCAGA TTGCAGATAT ACTGTCAACA 
GCTGGGACTG TGGTTACCAT CACAATCATG CCTACTTTTA TCTTCGAACA CATTATTAAA 
CGGATGGCTC CCAGCATTAT GAAAAGCCTG ATGGATCACA CCATTCCTGA AGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030109532.1
CDS	185..1081
Translation	MSLYPSLEDLKVDKVIQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSLNEAEICESMPMVSGAPAQGLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDHTIPEV

Target ORF information:

RefSeq Version	XM_030253672.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus syndecan binding protein (Sdcbp), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030253672.1

ORF Insert Sequence:

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGTTGGTAG CAAGACCATC CAGTGTGAAC TATATGGTAG CACCTGTGAC AGGTAACGAT 
GCTGGAATTC GGAGAGCAGA AATTAAGCAA GGGATCCGTG AAGTTATTTT GTGTAAGGAT 
CAAGATGGAA AAATTGGGCT CAGACTTAAG TCAATAGATA ATGGTATATT TGTTCAACTC 
GTCCAGGCTA ATTCCCCAGC CTCCTTGGTT GGACTGAGAT TTGGGGACCA GGTGCTCCAG 
ATCAACGGTG AAAACTGTGC GGGCTGGAGC TCTGATAAGG CACACAAGGT GCTCAAGCAG 
GCGTTTGGAG AGAAGATCAC CATGACGATC CGTGACAGGC CCTTTGAACG GACAGTTACT 
ATGCATAAGG ACAGCAGTGG ACATGTTGGC TTTATCTTTA AAAGTGGAAA AATCACATCC 
ATAGTAAAAG ATAGTTCTGC TGCCAGAAAC GGCCTCCTCA CTGATCACCA CATCTGTGAG 
ATCAACGGAC AGAACGTCAT TGGCTTGAAG GATGCTCAGA TTGCAGATAT ACTGTCAACA 
GCTGGGACTG TGGTTACCAT CACAATCATG CCTACTTTTA TCTTCGAACA CATTATTAAA 
CGGATGGCTC CCAGCATTAT GAAAAGCCTG ATGGATCACA CCATTCCTGA AGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sdcbp ( XM_006538084.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006538147.1 Mus musculus syndecan binding protein (Sdcbp), transcript variant X1, mRNA.

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CloneID	OMu18862
Clone ID Related Accession (Same CDS sequence)	XM_006538084.4 , XM_006538084.3 , NM_001098227.1
Accession Version	XM_006538084.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	syntenin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006538084.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGCAGTTGG TAGCAAGACC ATCCAGTGTG AACTATATGG TAGCACCTGT GACAGGTAAC 
GATGCTGGAA TTCGGAGAGC AGAAATTAAG CAAGGGATCC GTGAAGTTAT TTTGTGTAAG 
GATCAAGATG GAAAAATTGG GCTCAGACTT AAGTCAATAG ATAATGGTAT ATTTGTTCAA 
CTCGTCCAGG CTAATTCCCC AGCCTCCTTG GTTGGACTGA GATTTGGGGA CCAGGTGCTC 
CAGATCAACG GTGAAAACTG TGCGGGCTGG AGCTCTGATA AGGCACACAA GGTGCTCAAG 
CAGGCGTTTG GAGAGAAGAT CACCATGACG ATCCGTGACA GGCCCTTTGA ACGGACAGTT 
ACTATGCATA AGGACAGCAG TGGACATGTT GGCTTTATCT TTAAAAGTGG AAAAATCACA 
TCCATAGTAA AAGATAGTTC TGCTGCCAGA AACGGCCTCC TCACTGATCA CCACATCTGT 
GAGATCAACG GACAGAACGT CATTGGCTTG AAGGATGCTC AGATTGCAGA TATACTGTCA 
ACAGCTGGGA CTGTGGTTAC CATCACAATC ATGCCTACTT TTATCTTCGA ACACATTATT 
AAACGGATGG CTCCCAGCAT TATGAAAAGC CTGATGGATC ACACCATTCC TGAAGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006538147.1
CDS	204..1103
Translation	MSLYPSLEDLKVDKVIQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSLNEAEICESMPMVSGAPAQGQLVARPSSVNYMVAPVTGNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDHTIPEV

Target ORF information:

RefSeq Version	XM_006538084.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus syndecan binding protein (Sdcbp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006538084.4

ORF Insert Sequence:

ATGTCTCTTT ATCCATCTCT TGAAGATTTG AAGGTAGACA AAGTAATTCA GGCTCAAACT 
GCTTATTCTG CCAATCCCGC CAGCCAAGCA TTTGTTCTGG TGGATGCTTC TGCTGCTCTC 
CCTCCAGATG GAAATCTGTA TCCTAAACTG TATCCAGAGC TCTCTCAATA CATGGGACTG 
TCTTTAAATG AAGCTGAAAT ATGTGAGAGC ATGCCCATGG TCTCTGGAGC ACCAGCACAA 
GGGCAGTTGG TAGCAAGACC ATCCAGTGTG AACTATATGG TAGCACCTGT GACAGGTAAC 
GATGCTGGAA TTCGGAGAGC AGAAATTAAG CAAGGGATCC GTGAAGTTAT TTTGTGTAAG 
GATCAAGATG GAAAAATTGG GCTCAGACTT AAGTCAATAG ATAATGGTAT ATTTGTTCAA 
CTCGTCCAGG CTAATTCCCC AGCCTCCTTG GTTGGACTGA GATTTGGGGA CCAGGTGCTC 
CAGATCAACG GTGAAAACTG TGCGGGCTGG AGCTCTGATA AGGCACACAA GGTGCTCAAG 
CAGGCGTTTG GAGAGAAGAT CACCATGACG ATCCGTGACA GGCCCTTTGA ACGGACAGTT 
ACTATGCATA AGGACAGCAG TGGACATGTT GGCTTTATCT TTAAAAGTGG AAAAATCACA 
TCCATAGTAA AAGATAGTTC TGCTGCCAGA AACGGCCTCC TCACTGATCA CCACATCTGT 
GAGATCAACG GACAGAACGT CATTGGCTTG AAGGATGCTC AGATTGCAGA TATACTGTCA 
ACAGCTGGGA CTGTGGTTAC CATCACAATC ATGCCTACTT TTATCTTCGA ACACATTATT 
AAACGGATGG CTCCCAGCAT TATGAAAAGC CTGATGGATC ACACCATTCC TGAAGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells.
Oncotarget8(24)38886-38901(2017 Jun)
Tae N,Lee S,Kim O,Park J,Na S,Lee JH

Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
Oncotarget7(30)46848-46861(2016 Jul)
Das SK,Guo C,Pradhan AK,Bhoopathi P,Talukdar S,Shen XN,Emdad L,Subler MA,Windle JJ,Sarkar D,Wang XY,Fisher PB

Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.
Nature communications66842(2015 Apr)
Sugiura H,Yasuda S,Katsurabayashi S,Kawano H,Endo K,Takasaki K,Iwasaki K,Ichikawa M,Kobayashi T,Hino O,Yamagata K

Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells.
Frontiers in pharmacology6241(2015)
Kashyap R,Roucourt B,Lembo F,Fares J,Carcavilla AM,Restouin A,Zimmermann P,Ghossoub R

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Sdcbp cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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