C1ra cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	C1ra
Entrez Gene ID	50909
Full Name	complement component 1, r subcomponent A
Synonyms	AI132558,C1r,mC1rA
General protein information	Preferred Names complement component 1, r subcomponent A Names complement C1r-A subcomponent complement component 1 subcomponent r-A complement component 1, r-A subcomponent
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 F2

mRNA and Protein(s)

mRNA	Protein	Name
NM_023143.3	NP_075632.3	complement C1r-A subcomponent precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	C1R	XP_416518.2
Pan troglodytes (chimpanzee)	C1R	NP_001029292.1
Canis lupus familiaris (dog)	C1R	XP_005637266.1
Mus musculus (house mouse)	C1ra	NP_075632.3
Xenopus tropicalis (tropical clawed frog)	LOC100498646	XP_002941255.1
Homo sapiens (human)	C1R	NP_001724.3
Mus musculus (house mouse)	C1rb	NP_001106827.1
Rattus norvegicus (Norway rat)	C1r	NP_001128027.1
Xenopus tropicalis (tropical clawed frog)	LOC100485749	XP_002941260.2

Gene Ontology
Bibliography

Related articles in PubMed

Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.
Boyle MP, Bernard A, Thompson CL, Ng L, Boe A, Mortrud M, Hawrylycz MJ, Jones AR, Hevner RF, Lein ES
The Journal of comparative neurology519(11)2061-89(2011 Aug)

IFN-gamma upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1.
Byun SJ, Jeon IS, Lee H, Kim TY
The Journal of investigative dermatology127(5)1187-96(2007 May)

Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.
Bernhard OK, Kapp EA, Simpson RJ
Journal of proteome research6(3)987-95(2007 Mar)

Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system.
Garnier G, Circolo A, Xu Y, Volanakis JE
The Biochemical journal371(Pt 2)631-40(2003 Apr)

Identification of cDNA encoding a serine protease homologous to human complement C1r precursor from grafted mouse skin.
Byun SJ, Bahk YY, Ryoo ZY, Kim KE, Hwang HY, Lee JW, Yi JY, Kim TY
The Journal of investigative dermatology116(3)374-9(2001 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We conclude that IFN-gamma stimulates mC1rA gene expression via IRF-1 in mouse keratinocytes.
Title: IFN-gamma upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1.

This and C1s genes are duplicated in mice; differential expression generates alternative isomorphs in the liver and in the male reproductive system.
Title: Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system.

The following C1ra gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C1ra cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00253	NM_023143.3 Latest version!	Mus musculus complement component 1, r subcomponent A (C1ra), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$419.30 $599.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C1ra ( NM_023143.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_075632.3 Mus musculus complement component 1, r subcomponent A (C1ra), mRNA.

Price & Availability↑

CloneID	OMu00253
Clone ID Related Accession (Same CDS sequence)	NM_023143.3
Accession Version	NM_023143.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	complement C1r-A subcomponent precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY014972.1, AF148216.1, AI119268.1 and AK019687.1. On Jan 9, 2008 this sequence version replaced NM_023143.2. ##Evidence-Data-START## Transcript exon combination :: BC093528.1, AF148216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTGGCTCT TTGCCCTCCT GGTGACCCTG TTCTATGGGG TGGAAGGCTC CATTTACCTC 
CCTCAGAAGC TCTATGGAGA GGTGACCTCC CCTCTGTATC CCAAGCCTTA CCCCAGTGAC 
TTGGAGACAA CCACTGTGAT CACTGTCCCC ATGGGGTACA GGGTGAAGCT GGTCTTCTGG 
CAGTTTGACG TGGAGCCTTC TGAAGGCTGC TTCTATGACT ATGTTAAGAT TTCTGCTGAT 
AAGCAAACAC TGGGGAGGTT CTGTGGGCAG CTGGATTCTC CCCTGGGCAA CCCCCCAGGA 
AGCAAGGAAT TCATGTCCCA AGGAAACAAG ATGCTGCTGA CCTTCCACAC AGACTTCTCC 
AATGAGGAGA ATGGGACCAT CATGTTCTAC AAGGGCTTCC TGGCCTACTA CCAGGCTGTA 
GACCTTGATG AATGTGCATC GCAGCCCAAC TCAGTGGAAG AGGGTTTGCA GCCCCGATGC 
CAACATCTGT GTCACAACTA TGTTGGAGGC TACTTCTGTT CCTGCCATCC TGGCTATGAG 
CTTCAGAAAG ATGGGCAATC CTGCCAGGCT GAGTGCAGCA GTGAGCTCTA CACAGAGCCC 
TCAGGCTATG TCTCCAGCCT TGAATACCCT CAGCCCTATC CACCGGATCT ACGCTGCAAC 
TACAGCATCC GGGTGGAGAG GGGCCTCACT GTGCACCTCA AGTTCCTGGA TCCTTTTGAA 
ATTGATGACC ACCAGCAAGT GCACTGCCCC TATGACCAGC TCCAGATCTA CGCTAATGGG 
AAGAACTTGG GTGAATTCTG TGGAAAGCAA AGGCCTCCAG ACCTTGACAC CAGCAGCAAT 
GCAGTGGATC TGCTGTTCTT CACAGATGAG TCAGGGGACA GCCGAGGCTG GAAGCTGCAC 
TACACCACTG AAACCATCAA GTGCCCCCAG CCCAAGGCTC TGGATGAGTT CACCATCATC 
CAGGATCCGC AGCCTCAGTA CCAGTTCCGG GATTACTTCA TTGTCACCTG CAAGCAAGGC 
TACCAGCTCA TGGAGGGAAA TCAGGCGCTA CTCTCCTTCA CAGCTGTTTG CCAGAATGAT 
GGCACATGGC ATCGTGCCAT GCCCAGGTGC AAGATCAAGA ACTGTGGGCA GCCCCAAAGC 
CTGTCTAATG GGGACTTCCG CTACATCACC ACAAAAGGCG TGACCACCTA TGAAGCCAGT 
ATCCAGTATC ACTGCCATGA ACCATATTAC AAGATGCTGA CCAGAGCTGG CAGCAGCGAG 
TCCATGCGAG GGATATATAC CTGCACAGCC CAAGGCATTT GGAAGAATGA AGAGGAAGGA 
GAGAAAATGC CCCGGTGTCT GCCAGTGTGT GGGAAACCTG TCAACCCTGT GACACAGAAG 
GAGCGCATCA TCAGAGGGCA GCCAGCCAGG CCCGGCAACT TCCCCTGGCA GGCCTTCACC 
ACTACCCACG GGCGAGGGGG TGGGGCCCTG CTTGGAGACC GCTGGATCCT CACAGCAGCC 
CACACCATCT ACCCCAAGCA TCACAACAAG GAAAACGACA ATGCCAACCC CAAAATGCTT 
GTTTTCCTGG GCCACACAAA TGTGGAACAG ATCAAAAAAC TGGGACATCA CCCAGTCCGT 
AGGGTCATCA TACACCCAGA CTACCGCCAA GATGAACCTA ACAATTTTGA AGGAGACATT 
GCTCTACTGG AGCTGGAAAA CAGTGTCACA CTGGGCCCCG AACTCCTCCC CATCTGTCTC 
CCAGACAATG AGACCTTCTA TGGCCAAGGC CTCATGGGTT ATGTCAGCGG ATTCGGGATA 
ACAGAAGATA AGTTAGCTTT CGATCTCAGG TTCGTCAGAC TGCCTGTAGC TGACAGTGAG 
GCATGCCAGA GATGGCTCCA GACAAAAAAG GATACTTCTC CATTTTCTCA AAATATGTTC 
TGTTCTGGGG ACCCAGCTGT ACAGCAAGAC GCCTGCCAAG GGGACAGTGG GGGTGTTTTT 
GCAGTCAGGG ACAGAAATCG TGATATTTGG GTGGCTACGG GCATCGTATC CTGGGGCATT 
GGGTGTGGTG AGGGATATGG CTTCTACACC AAGGTACTGA ATTATGTTGA CTGGATCAAG 
AAAGAGATGG GAGACGAAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075632.3
CDS	179..2302
Translation	MWLFALLVTLFYGVEGSIYLPQKLYGEVTSPLYPKPYPSDLETTTVITVPMGYRVKLVFWQFDVEPSEGCFYDYVKISADKQTLGRFCGQLDSPLGNPPGSKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASQPNSVEEGLQPRCQHLCHNYVGGYFCSCHPGYELQKDGQSCQAECSSELYTEPSGYVSSLEYPQPYPPDLRCNYSIRVERGLTVHLKFLDPFEIDDHQQVHCPYDQLQIYANGKNLGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLHYTTETIKCPQPKALDEFTIIQDPQPQYQFRDYFIVTCKQGYQLMEGNQALLSFTAVCQNDGTWHRAMPRCKIKNCGQPQSLSNGDFRYITTKGVTTYEASIQYHCHEPYYKMLTRAGSSESMRGIYTCTAQGIWKNEEEGEKMPRCLPVCGKPVNPVTQKERIIRGQPARPGNFPWQAFTTTHGRGGGALLGDRWILTAAHTIYPKHHNKENDNANPKMLVFLGHTNVEQIKKLGHHPVRRVIIHPDYRQDEPNNFEGDIALLELENSVTLGPELLPICLPDNETFYGQGLMGYVSGFGITEDKLAFDLRFVRLPVADSEACQRWLQTKKDTSPFSQNMFCSGDPAVQQDACQGDSGGVFAVRDRNRDIWVATGIVSWGIGCGEGYGFYTKVLNYVDWIKKEMGDEN

Target ORF information:

RefSeq Version	NM_023143.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 1, r subcomponent A (C1ra), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023143.3

ORF Insert Sequence:

ATGTGGCTCT TTGCCCTCCT GGTGACCCTG TTCTATGGGG TGGAAGGCTC CATTTACCTC 
CCTCAGAAGC TCTATGGAGA GGTGACCTCC CCTCTGTATC CCAAGCCTTA CCCCAGTGAC 
TTGGAGACAA CCACTGTGAT CACTGTCCCC ATGGGGTACA GGGTGAAGCT GGTCTTCTGG 
CAGTTTGACG TGGAGCCTTC TGAAGGCTGC TTCTATGACT ATGTTAAGAT TTCTGCTGAT 
AAGCAAACAC TGGGGAGGTT CTGTGGGCAG CTGGATTCTC CCCTGGGCAA CCCCCCAGGA 
AGCAAGGAAT TCATGTCCCA AGGAAACAAG ATGCTGCTGA CCTTCCACAC AGACTTCTCC 
AATGAGGAGA ATGGGACCAT CATGTTCTAC AAGGGCTTCC TGGCCTACTA CCAGGCTGTA 
GACCTTGATG AATGTGCATC GCAGCCCAAC TCAGTGGAAG AGGGTTTGCA GCCCCGATGC 
CAACATCTGT GTCACAACTA TGTTGGAGGC TACTTCTGTT CCTGCCATCC TGGCTATGAG 
CTTCAGAAAG ATGGGCAATC CTGCCAGGCT GAGTGCAGCA GTGAGCTCTA CACAGAGCCC 
TCAGGCTATG TCTCCAGCCT TGAATACCCT CAGCCCTATC CACCGGATCT ACGCTGCAAC 
TACAGCATCC GGGTGGAGAG GGGCCTCACT GTGCACCTCA AGTTCCTGGA TCCTTTTGAA 
ATTGATGACC ACCAGCAAGT GCACTGCCCC TATGACCAGC TCCAGATCTA CGCTAATGGG 
AAGAACTTGG GTGAATTCTG TGGAAAGCAA AGGCCTCCAG ACCTTGACAC CAGCAGCAAT 
GCAGTGGATC TGCTGTTCTT CACAGATGAG TCAGGGGACA GCCGAGGCTG GAAGCTGCAC 
TACACCACTG AAACCATCAA GTGCCCCCAG CCCAAGGCTC TGGATGAGTT CACCATCATC 
CAGGATCCGC AGCCTCAGTA CCAGTTCCGG GATTACTTCA TTGTCACCTG CAAGCAAGGC 
TACCAGCTCA TGGAGGGAAA TCAGGCGCTA CTCTCCTTCA CAGCTGTTTG CCAGAATGAT 
GGCACATGGC ATCGTGCCAT GCCCAGGTGC AAGATCAAGA ACTGTGGGCA GCCCCAAAGC 
CTGTCTAATG GGGACTTCCG CTACATCACC ACAAAAGGCG TGACCACCTA TGAAGCCAGT 
ATCCAGTATC ACTGCCATGA ACCATATTAC AAGATGCTGA CCAGAGCTGG CAGCAGCGAG 
TCCATGCGAG GGATATATAC CTGCACAGCC CAAGGCATTT GGAAGAATGA AGAGGAAGGA 
GAGAAAATGC CCCGGTGTCT GCCAGTGTGT GGGAAACCTG TCAACCCTGT GACACAGAAG 
GAGCGCATCA TCAGAGGGCA GCCAGCCAGG CCCGGCAACT TCCCCTGGCA GGCCTTCACC 
ACTACCCACG GGCGAGGGGG TGGGGCCCTG CTTGGAGACC GCTGGATCCT CACAGCAGCC 
CACACCATCT ACCCCAAGCA TCACAACAAG GAAAACGACA ATGCCAACCC CAAAATGCTT 
GTTTTCCTGG GCCACACAAA TGTGGAACAG ATCAAAAAAC TGGGACATCA CCCAGTCCGT 
AGGGTCATCA TACACCCAGA CTACCGCCAA GATGAACCTA ACAATTTTGA AGGAGACATT 
GCTCTACTGG AGCTGGAAAA CAGTGTCACA CTGGGCCCCG AACTCCTCCC CATCTGTCTC 
CCAGACAATG AGACCTTCTA TGGCCAAGGC CTCATGGGTT ATGTCAGCGG ATTCGGGATA 
ACAGAAGATA AGTTAGCTTT CGATCTCAGG TTCGTCAGAC TGCCTGTAGC TGACAGTGAG 
GCATGCCAGA GATGGCTCCA GACAAAAAAG GATACTTCTC CATTTTCTCA AAATATGTTC 
TGTTCTGGGG ACCCAGCTGT ACAGCAAGAC GCCTGCCAAG GGGACAGTGG GGGTGTTTTT 
GCAGTCAGGG ACAGAAATCG TGATATTTGG GTGGCTACGG GCATCGTATC CTGGGGCATT 
GGGTGTGGTG AGGGATATGG CTTCTACACC AAGGTACTGA ATTATGTTGA CTGGATCAAG 
AAAGAGATGG GAGACGAAAA CTGA