Fbxo6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fbxo6
Entrez Gene ID	50762
Full Name	F-box protein 6
Synonyms	AA408845,FBG2,Fbs2,Fbx6b,Fbxo6b
General protein information	Preferred Names F-box protein 6 Names F-box only protein 6 F-box only protein 6b F-box protein that recognizes sugar chains 2 F-box/G-domain protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 4 Map Location: 4 E2\|4 78.67 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001163706.1	NP_001157178.1	F-box only protein 6
NM_001163705.1	NP_001157177.1	F-box only protein 6
NM_015797.4	NP_056612.1	F-box only protein 6
NM_001163707.1	NP_001157179.1	F-box only protein 6
NM_001163704.1	NP_001157176.1	F-box only protein 6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FBXO6	NP_001233333.1
	LOC722740	XP_002802223.1
Danio rerio (zebrafish)	si:rp71-1k13.6	XP_005162152.1
Homo sapiens (human)	FBXO6	NP_060908.1
Danio rerio (zebrafish)	si:dkey-147f3.4	NP_001153111.1
Xenopus tropicalis (tropical clawed frog)	fbxo6	XP_004916183.1
Canis lupus familiaris (dog)	FBXO6	XP_005618058.1
Danio rerio (zebrafish)	zgc:100832	NP_001003542.1
Danio rerio (zebrafish)	zgc:153722	NP_001070044.1
Bos taurus (cattle)	FBXO6	NP_001029605.1
Danio rerio (zebrafish)	fbxo44	NP_001008577.1
Danio rerio (zebrafish)	zgc:114174	NP_001020352.1
Danio rerio (zebrafish)	zgc:114081	NP_001025364.1
Mus musculus (house mouse)	Fbxo6	NP_001157176.1
Rattus norvegicus (Norway rat)	Fbxo6	NP_620272.3
Gallus gallus (chicken)	FBXO6	XP_417649.2
Danio rerio (zebrafish)	zgc:173570	NP_001104672.1

Gene Ontology
Bibliography

Related articles in PubMed

Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.
Groisman B, Shenkman M, Ron E, Lederkremer GZ
The Journal of biological chemistry286(2)1292-300(2011 Jan)

Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.
Yoshida Y, Adachi E, Fukiya K, Iwai K, Tanaka K
EMBO reports6(3)239-44(2005 Mar)

Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Bliskovsky V, Ramsay ES, Scott J, DuBois W, Shi W, Zhang S, Qian X, Lowy DR, Mock BA
Proceedings of the National Academy of Sciences of the United States of America100(25)14982-7(2003 Dec)

Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.
Yoshida Y, Tokunaga F, Chiba T, Iwai K, Tanaka K, Tai T
The Journal of biological chemistry278(44)43877-84(2003 Oct)

A family of mammalian F-box proteins.
Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW
Current biology : CB9(20)1180-2(1999 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Fbs2 is a novel member of F-box protein family that recognizes N-glycans and plays a role in ERAD
Title: Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.

The following Fbxo6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbxo6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu09351	NM_015797.4 Latest version!	Mus musculus F-box protein 6 (Fbxo6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu09351	NM_001163706.1 Latest version!	Mus musculus F-box protein 6 (Fbxo6), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu09351	NM_001163705.1 Latest version!	Mus musculus F-box protein 6 (Fbxo6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu09351	NM_001163707.1 Latest version!	Mus musculus F-box protein 6 (Fbxo6), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OMu09351	NM_001163704.1 Latest version!	Mus musculus F-box protein 6 (Fbxo6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fbxo6 ( NM_001163706.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157178.1 Mus musculus F-box protein 6 (Fbxo6), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu09351
Clone ID Related Accession (Same CDS sequence)	NM_001163706.1 , NM_001163705.1 , NM_015797.4 , NM_001163707.1 , NM_001163704.1
Accession Version	NM_001163706.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-23
Organism	Mus musculus(house mouse)
Product	F-box only protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK171483.1 and AK165867.1. Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK170743.1, AK171483.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157178.1
CDS	118..1005
Translation	MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR

Target ORF information:

RefSeq Version	NM_001163706.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box protein 6 (Fbxo6), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163706.1

ORF Insert Sequence:

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( NM_001163705.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157177.1 Mus musculus F-box protein 6 (Fbxo6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu09351
Clone ID Related Accession (Same CDS sequence)	NM_001163706.1 , NM_001163705.1 , NM_015797.4 , NM_001163707.1 , NM_001163704.1
Accession Version	NM_001163705.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	F-box only protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB854497.1, BY260050.1, AK171483.1 and AK165867.1. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BF143106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157177.1
CDS	126..1013
Translation	MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR

Target ORF information:

RefSeq Version	NM_001163705.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box protein 6 (Fbxo6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163705.1

ORF Insert Sequence:

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( NM_015797.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_056612.1 Mus musculus F-box protein 6 (Fbxo6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu09351
Clone ID Related Accession (Same CDS sequence)	NM_001163706.1 , NM_001163705.1 , NM_015797.4 , NM_001163707.1 , NM_001163704.1
Accession Version	NM_015797.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-23
Organism	Mus musculus(house mouse)
Product	F-box only protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB854497.1 and AK165867.1. On Jul 30, 2009 this sequence version replaced NM_015797.3. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-6 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK165867.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056612.1
CDS	868..1755
Translation	MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR

Target ORF information:

RefSeq Version	NM_015797.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box protein 6 (Fbxo6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015797.4

ORF Insert Sequence:

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( NM_001163707.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157179.1 Mus musculus F-box protein 6 (Fbxo6), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu09351
Clone ID Related Accession (Same CDS sequence)	NM_001163706.1 , NM_001163705.1 , NM_015797.4 , NM_001163707.1 , NM_001163704.1
Accession Version	NM_001163707.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	F-box only protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY164736.1, AK171483.1 and AK165867.1. Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BE916711.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157179.1
CDS	153..1040
Translation	MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR

Target ORF information:

RefSeq Version	NM_001163707.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box protein 6 (Fbxo6), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163707.1

ORF Insert Sequence:

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxo6 ( NM_001163704.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001157176.1 Mus musculus F-box protein 6 (Fbxo6), transcript variant 2, mRNA.

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CloneID	OMu09351
Clone ID Related Accession (Same CDS sequence)	NM_001163706.1 , NM_001163705.1 , NM_015797.4 , NM_001163707.1 , NM_001163704.1
Accession Version	NM_001163704.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	F-box only protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB854497.1, AK150612.1 and AK165867.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK150612.1, AK144715.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157176.1
CDS	342..1229
Translation	MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR

Target ORF information:

RefSeq Version	NM_001163704.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box protein 6 (Fbxo6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163704.1

ORF Insert Sequence:

ATGGTCCACA TCAACGAGCT GCCAGAGAAC ATTCTCCTGG AGCTGTTCAT CCATATCCCG 
GCCCCACAGC TGCTGCGCAA CTGCCGCCTG GTCTGCCGCC TCTGGCGAGA CCTCATCGAT 
GTGGTGTCCC TATGGAAGCG CAAGAGTCTT CGAGAGGGCT TCTTCACCAA AGACCGGTGC 
GAGCCCGTGG AAGACTGGAA GGTCTTCTAT ATCCTGTGCA GCCTGCAGAG GAACCTCCTT 
CGGAACCCGT GTGCTGAAGA GAACCTGAGC TCATGGCGGA TAGACTCCAA CGGAGGGGAT 
CGCTGGAAGG TGGAGACGCT CCCTGGGAGC TGTGGCACAA GCTTTCCTGA CAACAAGGTC 
AAGAAGTATT TTGTCACCTC TTTTGAGATG TGCCTCAAAT CCCAGATGGT GGACCTCAAA 
GCTGAGGGCT ACTGCGAGGA GCTGATGGAC ACCTTTCGGC CTGACATTGT GGTTAAGGAC 
TGGGTTGCCC CCAGAGCAGA CTGTGGCTGC ACCTATCAAC TCCGGGTACA GCTGGCCTCT 
GCGGACTACA TTGTCTTGGC CTCTTTTGAG CCTCCACCTG TGACATTCCA ACAGTGGAAT 
GATGCCAAAT GGCAAGAGAT TTCCCACACC TTCTCTGATT ACCCTCCAGG TGTCCGTCAC 
ATCCTTTTTC AACACGGGGG CCAGGACACT CAGTTCTGGA AAGGCTGGTA CGGCCCCCGT 
GTCACCAACA GCAGCATCAT TATCAGCCAC AGGACAGCCA AGAACCCTCC CCCTGCCAGA 
ACTCTACCGG AAGAAACTGT AGTAATCGGA AGGAGACGGC GAGCTTCGGA CTCCAACACT 
CATGAGGGTT TCTTCTGGCA AGGGCTATGG CAAAGGCTAA GGCGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.
The Journal of biological chemistry286(2)1292-300(2011 Jan)
Groisman B,Shenkman M,Ron E,Lederkremer GZ

Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.
EMBO reports6(3)239-44(2005 Mar)
Yoshida Y,Adachi E,Fukiya K,Iwai K,Tanaka K

Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene.
Proceedings of the National Academy of Sciences of the United States of America100(25)14982-7(2003 Dec)
Bliskovsky V,Ramsay ES,Scott J,DuBois W,Shi W,Zhang S,Qian X,Lowy DR,Mock BA

Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.
The Journal of biological chemistry278(44)43877-84(2003 Oct)
Yoshida Y,Tokunaga F,Chiba T,Iwai K,Tanaka K,Tai T

A family of mammalian F-box proteins.
Current biology : CB9(20)1180-2(1999 Oct)
Winston JT,Koepp DM,Zhu C,Elledge SJ,Harper JW

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Fbxo6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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