Fbxl17 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fbxl17
Entrez Gene ID	50758
Full Name	F-box and leucine-rich repeat protein 17
Synonyms	6330576B01Rik,AI452053,BB073797,C130023C01Rik,Fbx13,Fbxo13
General protein information	Preferred Names F-box and leucine-rich repeat protein 17 Names F-box/LRR-repeat protein 17 F-box only protein 13
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 E1.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006524600.4	XP_006524663.1	F-box/LRR-repeat protein 17 isoform X1
NM_015794.1	NP_056609.1	F-box/LRR-repeat protein 17
XM_006524600.3	XP_006524663.1	F-box/LRR-repeat protein 17 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FBXL17	XP_850192.3
Mus musculus (house mouse)	Fbxl17	NP_056609.1
Danio rerio (zebrafish)	LOC795023	XP_001335097.5
	LOC710818	XP_002808481.1
Rattus norvegicus (Norway rat)	Fbxl17	NP_001101705.1
Gallus gallus (chicken)	FBXL17	XP_004949350.1
Homo sapiens (human)	FBXL17	NP_001156787.2
Pan troglodytes (chimpanzee)	FBXL17	XP_001137158.2

Gene Ontology
Bibliography

Related articles in PubMed

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, Bristow C, Th?z?nas ML, Finta C, Christianson JC, Buffa FM, Kessler BM, Sibson NR, Di Marcotullio L, Toftg?rd R, D'Angiolella V
The EMBO journal35(13)1400-16(2016 07)

Systematic analysis and nomenclature of mammalian F-box proteins.
Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW
Genes & development18(21)2573-80(2004 Nov)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

A family of mammalian F-box proteins.
Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW
Current biology : CB9(20)1180-2(1999 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fbxl17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fbxl17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu53817	XM_006524600.4 Latest version!	Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu10278	NM_015794.1 Latest version!	Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OMu53817	XM_006524600.3	Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fbxl17 ( XM_006524600.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006524663.1 Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu53817
Clone ID Related Accession (Same CDS sequence)	XM_006524600.4 , XM_006524600.3
Accession Version	XM_006524600.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	F-box/LRR-repeat protein 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006524600.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCACC TTCTCTCGAA GGAGCCGCGT AACCGCCCGA GCCAGAAGAG GCCTCGCTGC 
TGCAGCTGGT GTCGCCGCCG GCGCCCTCTC CTCAGACTGC CCCGCCGGGC TCTGGCCAAG 
GCGTCCCCGC AGCCCGCGGC GCCCCGGAGC CGGGACTGCT TCTTCCGCGG GCCCTGCATG 
CTCTGCTTCA TCGTGCACAG CCCCGGCGCG CCCGCCTCCG CCGGCCTAGA GGAGGAGCCG 
CCGCTCTCGC CACCGCCGCC GCCGCCGCGG GACGGGGCCT ACGCCGCCGT CTCCTCGCAG 
CACTTGGCGC GGCGCTACGC GGCCCTGGCC GCCGAGGACT GCGCCGCCGC CGCACGCCGC 
TTCCTGCTGT CCTCGGCCGC CGCCGCCGCC GCCGCTGCCT CGTCGCCCGC GTCCTGCTGC 
AAGGAGCTGG GGCTGGCCGC CGCCGCCGCC TGGGAGCAGC AGGGCCGGAG CCTCTTCCTG 
GCCGGCGTGG GGCCCGTGCG CTTCCTGGGA CCGCTGGCCG CCGTGCAGCT CTTCCGGGCA 
CCGCCGGCGC CGCCGCCGCA GGCCGAGCCC GCCACGGCCC TCGAGATGGT TTGCAAGCGG 
AAAGGGGCCG GGGTCCCCGC CTGCACCCCC TGCAAGCAGC CCCGTTGCGG CTGCGGGGGC 
TGCGGCGGGG GCGGCGGCGG CGGGGGAGGG CCCGCGGGAG GAGGTGCCTC GCCGCCGCGG 
CCGCCCGATG CCGGCTGCTG CCAGGCCCCG GAGCAGCCCC CGCCGCCGCT CTGCCCCGCG 
CCCGCCTCTC CCGCCTCAGA GTGTGCCCCC ATCGTGGCCG CCGCCGGGGA CACAGTCCGA 
GCCGGGGGCA CCGCCCCCTC GTCTGCCCAG CAGCAGCCCG AGAGCGGCGA CGCGGACTGT 
CAGGAGCCCC CCGAAAACCC CTGCGACTGT CACAGGGAGC CGCCCCCCGA GATCCCAGAC 
ATCAACCAAC TGCCGCCGTC CATCCTGCTT AAGATATTTT CCAATTTGTC CCTGAACGAA 
CGCTGCCTTT CTGCATCGTT GGTTTGCAAG TACTGGCGTG ACCTTTGCTT AGATTTCCAG 
TTTTGGAAGC AGCTGGACCT TAGTAGTCGT CAGCAGGTTA CTGATGAATT ATTGGAAAAA 
ATTGCCTCCA GAAGTCAGAA TATAATTGAG ATTAACATTT CTGATTGTCG AAGTCTGTCT 
GACAGTGGCG TGTGTGTCCT AGCATTTAAG TGTCCTGGAC TTCTTAGGTA TACAGCCTAC 
AGGTGTAAGC AGCTTTCTGA CACCTCAATC ATTGCGGTCG CGTCTCACTG CCCTTTACTG 
CAGAAAGTCC ACGTAGGCAA CCAGGACAAG CTCACCGATG AAGGACTTAA GCAGTGGACA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006524663.1
CDS	4168..5550
Translation	MGHLLSKEPRNRPSQKRPRCCSWCRRRRPLLRLPRRALAKASPQPAAPRSRDCFFRGPCMLCFIVHSPGAPASAGLEEEPPLSPPPPPPRDGAYAAVSSQHLARRYAALAAEDCAAAARRFLLSSAAAAAAAASSPASCCKELGLAAAAAWEQQGRSLFLAGVGPVRFLGPLAAVQLFRAPPAPPPQAEPATALEMVCKRKGAGVPACTPCKQPRCGCGGCGGGGGGGGGPAGGGASPPRPPDAGCCQAPEQPPPPLCPAPASPASECAPIVAAAGDTVRAGGTAPSSAQQQPESGDADCQEPPENPCDCHREPPPEIPDINQLPPSILLKIFSNLSLNERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQWT

Target ORF information:

RefSeq Version	XM_006524600.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006524600.4

ORF Insert Sequence:

ATGGGCCACC TTCTCTCGAA GGAGCCGCGT AACCGCCCGA GCCAGAAGAG GCCTCGCTGC 
TGCAGCTGGT GTCGCCGCCG GCGCCCTCTC CTCAGACTGC CCCGCCGGGC TCTGGCCAAG 
GCGTCCCCGC AGCCCGCGGC GCCCCGGAGC CGGGACTGCT TCTTCCGCGG GCCCTGCATG 
CTCTGCTTCA TCGTGCACAG CCCCGGCGCG CCCGCCTCCG CCGGCCTAGA GGAGGAGCCG 
CCGCTCTCGC CACCGCCGCC GCCGCCGCGG GACGGGGCCT ACGCCGCCGT CTCCTCGCAG 
CACTTGGCGC GGCGCTACGC GGCCCTGGCC GCCGAGGACT GCGCCGCCGC CGCACGCCGC 
TTCCTGCTGT CCTCGGCCGC CGCCGCCGCC GCCGCTGCCT CGTCGCCCGC GTCCTGCTGC 
AAGGAGCTGG GGCTGGCCGC CGCCGCCGCC TGGGAGCAGC AGGGCCGGAG CCTCTTCCTG 
GCCGGCGTGG GGCCCGTGCG CTTCCTGGGA CCGCTGGCCG CCGTGCAGCT CTTCCGGGCA 
CCGCCGGCGC CGCCGCCGCA GGCCGAGCCC GCCACGGCCC TCGAGATGGT TTGCAAGCGG 
AAAGGGGCCG GGGTCCCCGC CTGCACCCCC TGCAAGCAGC CCCGTTGCGG CTGCGGGGGC 
TGCGGCGGGG GCGGCGGCGG CGGGGGAGGG CCCGCGGGAG GAGGTGCCTC GCCGCCGCGG 
CCGCCCGATG CCGGCTGCTG CCAGGCCCCG GAGCAGCCCC CGCCGCCGCT CTGCCCCGCG 
CCCGCCTCTC CCGCCTCAGA GTGTGCCCCC ATCGTGGCCG CCGCCGGGGA CACAGTCCGA 
GCCGGGGGCA CCGCCCCCTC GTCTGCCCAG CAGCAGCCCG AGAGCGGCGA CGCGGACTGT 
CAGGAGCCCC CCGAAAACCC CTGCGACTGT CACAGGGAGC CGCCCCCCGA GATCCCAGAC 
ATCAACCAAC TGCCGCCGTC CATCCTGCTT AAGATATTTT CCAATTTGTC CCTGAACGAA 
CGCTGCCTTT CTGCATCGTT GGTTTGCAAG TACTGGCGTG ACCTTTGCTT AGATTTCCAG 
TTTTGGAAGC AGCTGGACCT TAGTAGTCGT CAGCAGGTTA CTGATGAATT ATTGGAAAAA 
ATTGCCTCCA GAAGTCAGAA TATAATTGAG ATTAACATTT CTGATTGTCG AAGTCTGTCT 
GACAGTGGCG TGTGTGTCCT AGCATTTAAG TGTCCTGGAC TTCTTAGGTA TACAGCCTAC 
AGGTGTAAGC AGCTTTCTGA CACCTCAATC ATTGCGGTCG CGTCTCACTG CCCTTTACTG 
CAGAAAGTCC ACGTAGGCAA CCAGGACAAG CTCACCGATG AAGGACTTAA GCAGTGGACA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxl17 ( NM_015794.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_056609.1 Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), mRNA.

Price & Availability↑

CloneID	OMu10278
Clone ID Related Accession (Same CDS sequence)	NM_015794.1
Accession Version	NM_015794.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2106bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Mus musculus(house mouse)
Product	F-box/LRR-repeat protein 17
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ179644.1, CT025670.8, AF176529.1, AC154192.3 and BX515367.1. On or before Aug 10, 2009 this sequence version replaced XM_001478436.1, XM_925135.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.108573.1, AF176529.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCCACC TTCTCTCGAA GGAGCCGCGT AACCGCCCGA GCCAGAAGAG GCCTCGCTGC 
TGCAGCTGGT GTCGCCGCCG GCGCCCTCTC CTCAGACTGC CCCGCCGGGC TCTGGCCAAG 
GCGTCCCCGC AGCCCGCGGC GCCCCGGAGC CGGGACTGCT TCTTCCGCGG GCCCTGCATG 
CTCTGCTTCA TCGTGCACAG CCCCGGCGCG CCCGCCTCCG CCGGCCTAGA GGAGGAGCCG 
CCGCTCTCGC CACCGCCGCC GCCGCCGCGG GACGGGGCCT ACGCCGCCGT CTCCTCGCAG 
CACTTGGCGC GGCGCTACGC GGCCCTGGCC GCCGAGGACT GCGCCGCCGC CGCACGCCGC 
TTCCTGCTGT CCTCGGCCGC CGCCGCCGCC GCCGCTGCCT CGTCGCCCGC GTCCTGCTGC 
AAGGAGCTGG GGCTGGCCGC CGCCGCCGCC TGGGAGCAGC AGGGCCGGAG CCTCTTCCTG 
GCCGGCGTGG GGCCCGTGCG CTTCCTGGGA CCGCTGGCCG CCGTGCAGCT CTTCCGGGCA 
CCGCCGGCGC CGCCGCCGCA GGCCGAGCCC GCCACGGCCC TCGAGATGGT TTGCAAGCGG 
AAAGGGGCCG GGGTCCCCGC CTGCACCCCC TGCAAGCAGC CCCGTTGCGG CTGCGGGGGC 
TGCGGCGGGG GCGGCGGCGG CGGGGGAGGG CCCGCGGGAG GAGGTGCCTC GCCGCCGCGG 
CCGCCCGATG CCGGCTGCTG CCAGGCCCCG GAGCAGCCCC CGCCGCCGCT CTGCCCCGCG 
CCCGCCTCTC CCGCCTCAGA GTGTGCCCCC ATCGTGGCCG CCGCCGGGGA CACAGTCCGA 
GCCGGGGGCA CCGCCCCCTC GTCTGCCCAG CAGCAGCCCG AGAGCGGCGA CGCGGACTGT 
CAGGAGCCCC CCGAAAACCC CTGCGACTGT CACAGGGAGC CGCCCCCCGA GATCCCAGAC 
ATCAACCAAC TGCCGCCGTC CATCCTGCTT AAGATATTTT CCAATTTGTC CCTGAACGAA 
CGCTGCCTTT CTGCATCGTT GGTTTGCAAG TACTGGCGTG ACCTTTGCTT AGATTTCCAG 
TTTTGGAAGC AGCTGGACCT TAGTAGTCGT CAGCAGGTTA CTGATGAATT ATTGGAAAAA 
ATTGCCTCCA GAAGTCAGAA TATAATTGAG ATTAACATTT CTGATTGTCG AAGTCTGTCT 
GACAGTGGCG TGTGTGTCCT AGCATTTAAG TGTCCTGGAC TTCTTAGGTA TACAGCCTAC 
AGGTGTAAGC AGCTTTCTGA CACCTCAATC ATTGCGGTCG CGTCTCACTG CCCTTTACTG 
CAGAAAGTCC ACGTAGGCAA CCAGGACAAG CTCACCGATG AAGGACTTAA GCAGCTGGGC 
TCAAGATGCA GAGAACTCAA AGACATCCAT TTTGGCCAGT GTTACAAGAT CTCAGATGAA 
GGCATGATTG TCATAGCTAA GAGCTGCCTG AAGTTACAGA GGATATACAT GCAGGAAAAC 
AAATTAGTGA CAGATCAGTC AGTGAAGGCA TTTGCTGAGC ACTGTCCTGA ACTCCAGTAT 
GTTGGCTTCA TGGGTTGTTC AGTTACTTCC AAAGGAGTCA TTCACTTAAC CAAGCTAAGG 
AACCTGTCCA GCTTAGACCT CCGTCACATC ACTGAACTGG ATAATGAAAC CGTGATGGAA 
ATCGTCAAGA GGTGCAAAAA TCTCAGCTCT CTGAATCTCT GTCTGAACTG GATCATAAAC 
GACAGGTGTG TGGAGGTCAT TGCAAAGGAA GGACAGAACC TGAAAGAGCT GTACCTGGTG 
TCCTGTAAGA TCACTGATTA TGCACTGATA GCCATTGGGC GATACAGCGT GACCATAGAG 
ACTGTGGACG TCGGATGGTG TAAAGAAATC ACAGATCAAG GAGCCACCCT GATTGCACAG 
AGCAGCAAGT CCCTGAGATA CTTGGGCCTG ATGAGATGTG ACAAAGTCAA TGAATTGACA 
GTGGAGCAGC TGGTGCAGCA GTACCCGCAC ATCACCTTCA GCACCGTTCT GCAGGACTGC 
AAGAGGACCT TGGAGAGAGC CTACCAGATG GGCTGGACCC CCAATATGTC CGCTGCCACC 
TCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056609.1
CDS	564..2669
Translation	MGHLLSKEPRNRPSQKRPRCCSWCRRRRPLLRLPRRALAKASPQPAAPRSRDCFFRGPCMLCFIVHSPGAPASAGLEEEPPLSPPPPPPRDGAYAAVSSQHLARRYAALAAEDCAAAARRFLLSSAAAAAAAASSPASCCKELGLAAAAAWEQQGRSLFLAGVGPVRFLGPLAAVQLFRAPPAPPPQAEPATALEMVCKRKGAGVPACTPCKQPRCGCGGCGGGGGGGGGPAGGGASPPRPPDAGCCQAPEQPPPPLCPAPASPASECAPIVAAAGDTVRAGGTAPSSAQQQPESGDADCQEPPENPCDCHREPPPEIPDINQLPPSILLKIFSNLSLNERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSRCRELKDIHFGQCYKISDEGMIVIAKSCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSVTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNELTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAATS

Target ORF information:

RefSeq Version	NM_015794.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015794.1

ORF Insert Sequence:

ATGGGCCACC TTCTCTCGAA GGAGCCGCGT AACCGCCCGA GCCAGAAGAG GCCTCGCTGC 
TGCAGCTGGT GTCGCCGCCG GCGCCCTCTC CTCAGACTGC CCCGCCGGGC TCTGGCCAAG 
GCGTCCCCGC AGCCCGCGGC GCCCCGGAGC CGGGACTGCT TCTTCCGCGG GCCCTGCATG 
CTCTGCTTCA TCGTGCACAG CCCCGGCGCG CCCGCCTCCG CCGGCCTAGA GGAGGAGCCG 
CCGCTCTCGC CACCGCCGCC GCCGCCGCGG GACGGGGCCT ACGCCGCCGT CTCCTCGCAG 
CACTTGGCGC GGCGCTACGC GGCCCTGGCC GCCGAGGACT GCGCCGCCGC CGCACGCCGC 
TTCCTGCTGT CCTCGGCCGC CGCCGCCGCC GCCGCTGCCT CGTCGCCCGC GTCCTGCTGC 
AAGGAGCTGG GGCTGGCCGC CGCCGCCGCC TGGGAGCAGC AGGGCCGGAG CCTCTTCCTG 
GCCGGCGTGG GGCCCGTGCG CTTCCTGGGA CCGCTGGCCG CCGTGCAGCT CTTCCGGGCA 
CCGCCGGCGC CGCCGCCGCA GGCCGAGCCC GCCACGGCCC TCGAGATGGT TTGCAAGCGG 
AAAGGGGCCG GGGTCCCCGC CTGCACCCCC TGCAAGCAGC CCCGTTGCGG CTGCGGGGGC 
TGCGGCGGGG GCGGCGGCGG CGGGGGAGGG CCCGCGGGAG GAGGTGCCTC GCCGCCGCGG 
CCGCCCGATG CCGGCTGCTG CCAGGCCCCG GAGCAGCCCC CGCCGCCGCT CTGCCCCGCG 
CCCGCCTCTC CCGCCTCAGA GTGTGCCCCC ATCGTGGCCG CCGCCGGGGA CACAGTCCGA 
GCCGGGGGCA CCGCCCCCTC GTCTGCCCAG CAGCAGCCCG AGAGCGGCGA CGCGGACTGT 
CAGGAGCCCC CCGAAAACCC CTGCGACTGT CACAGGGAGC CGCCCCCCGA GATCCCAGAC 
ATCAACCAAC TGCCGCCGTC CATCCTGCTT AAGATATTTT CCAATTTGTC CCTGAACGAA 
CGCTGCCTTT CTGCATCGTT GGTTTGCAAG TACTGGCGTG ACCTTTGCTT AGATTTCCAG 
TTTTGGAAGC AGCTGGACCT TAGTAGTCGT CAGCAGGTTA CTGATGAATT ATTGGAAAAA 
ATTGCCTCCA GAAGTCAGAA TATAATTGAG ATTAACATTT CTGATTGTCG AAGTCTGTCT 
GACAGTGGCG TGTGTGTCCT AGCATTTAAG TGTCCTGGAC TTCTTAGGTA TACAGCCTAC 
AGGTGTAAGC AGCTTTCTGA CACCTCAATC ATTGCGGTCG CGTCTCACTG CCCTTTACTG 
CAGAAAGTCC ACGTAGGCAA CCAGGACAAG CTCACCGATG AAGGACTTAA GCAGCTGGGC 
TCAAGATGCA GAGAACTCAA AGACATCCAT TTTGGCCAGT GTTACAAGAT CTCAGATGAA 
GGCATGATTG TCATAGCTAA GAGCTGCCTG AAGTTACAGA GGATATACAT GCAGGAAAAC 
AAATTAGTGA CAGATCAGTC AGTGAAGGCA TTTGCTGAGC ACTGTCCTGA ACTCCAGTAT 
GTTGGCTTCA TGGGTTGTTC AGTTACTTCC AAAGGAGTCA TTCACTTAAC CAAGCTAAGG 
AACCTGTCCA GCTTAGACCT CCGTCACATC ACTGAACTGG ATAATGAAAC CGTGATGGAA 
ATCGTCAAGA GGTGCAAAAA TCTCAGCTCT CTGAATCTCT GTCTGAACTG GATCATAAAC 
GACAGGTGTG TGGAGGTCAT TGCAAAGGAA GGACAGAACC TGAAAGAGCT GTACCTGGTG 
TCCTGTAAGA TCACTGATTA TGCACTGATA GCCATTGGGC GATACAGCGT GACCATAGAG 
ACTGTGGACG TCGGATGGTG TAAAGAAATC ACAGATCAAG GAGCCACCCT GATTGCACAG 
AGCAGCAAGT CCCTGAGATA CTTGGGCCTG ATGAGATGTG ACAAAGTCAA TGAATTGACA 
GTGGAGCAGC TGGTGCAGCA GTACCCGCAC ATCACCTTCA GCACCGTTCT GCAGGACTGC 
AAGAGGACCT TGGAGAGAGC CTACCAGATG GGCTGGACCC CCAATATGTC CGCTGCCACC 
TCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fbxl17 ( XM_006524600.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006524663.1 Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu53817
Clone ID Related Accession (Same CDS sequence)	XM_006524600.4 , XM_006524600.3
Accession Version	XM_006524600.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	F-box/LRR-repeat protein 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006524600.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCACC TTCTCTCGAA GGAGCCGCGT AACCGCCCGA GCCAGAAGAG GCCTCGCTGC 
TGCAGCTGGT GTCGCCGCCG GCGCCCTCTC CTCAGACTGC CCCGCCGGGC TCTGGCCAAG 
GCGTCCCCGC AGCCCGCGGC GCCCCGGAGC CGGGACTGCT TCTTCCGCGG GCCCTGCATG 
CTCTGCTTCA TCGTGCACAG CCCCGGCGCG CCCGCCTCCG CCGGCCTAGA GGAGGAGCCG 
CCGCTCTCGC CACCGCCGCC GCCGCCGCGG GACGGGGCCT ACGCCGCCGT CTCCTCGCAG 
CACTTGGCGC GGCGCTACGC GGCCCTGGCC GCCGAGGACT GCGCCGCCGC CGCACGCCGC 
TTCCTGCTGT CCTCGGCCGC CGCCGCCGCC GCCGCTGCCT CGTCGCCCGC GTCCTGCTGC 
AAGGAGCTGG GGCTGGCCGC CGCCGCCGCC TGGGAGCAGC AGGGCCGGAG CCTCTTCCTG 
GCCGGCGTGG GGCCCGTGCG CTTCCTGGGA CCGCTGGCCG CCGTGCAGCT CTTCCGGGCA 
CCGCCGGCGC CGCCGCCGCA GGCCGAGCCC GCCACGGCCC TCGAGATGGT TTGCAAGCGG 
AAAGGGGCCG GGGTCCCCGC CTGCACCCCC TGCAAGCAGC CCCGTTGCGG CTGCGGGGGC 
TGCGGCGGGG GCGGCGGCGG CGGGGGAGGG CCCGCGGGAG GAGGTGCCTC GCCGCCGCGG 
CCGCCCGATG CCGGCTGCTG CCAGGCCCCG GAGCAGCCCC CGCCGCCGCT CTGCCCCGCG 
CCCGCCTCTC CCGCCTCAGA GTGTGCCCCC ATCGTGGCCG CCGCCGGGGA CACAGTCCGA 
GCCGGGGGCA CCGCCCCCTC GTCTGCCCAG CAGCAGCCCG AGAGCGGCGA CGCGGACTGT 
CAGGAGCCCC CCGAAAACCC CTGCGACTGT CACAGGGAGC CGCCCCCCGA GATCCCAGAC 
ATCAACCAAC TGCCGCCGTC CATCCTGCTT AAGATATTTT CCAATTTGTC CCTGAACGAA 
CGCTGCCTTT CTGCATCGTT GGTTTGCAAG TACTGGCGTG ACCTTTGCTT AGATTTCCAG 
TTTTGGAAGC AGCTGGACCT TAGTAGTCGT CAGCAGGTTA CTGATGAATT ATTGGAAAAA 
ATTGCCTCCA GAAGTCAGAA TATAATTGAG ATTAACATTT CTGATTGTCG AAGTCTGTCT 
GACAGTGGCG TGTGTGTCCT AGCATTTAAG TGTCCTGGAC TTCTTAGGTA TACAGCCTAC 
AGGTGTAAGC AGCTTTCTGA CACCTCAATC ATTGCGGTCG CGTCTCACTG CCCTTTACTG 
CAGAAAGTCC ACGTAGGCAA CCAGGACAAG CTCACCGATG AAGGACTTAA GCAGTGGACA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006524663.1
CDS	2155..3537
Translation	MGHLLSKEPRNRPSQKRPRCCSWCRRRRPLLRLPRRALAKASPQPAAPRSRDCFFRGPCMLCFIVHSPGAPASAGLEEEPPLSPPPPPPRDGAYAAVSSQHLARRYAALAAEDCAAAARRFLLSSAAAAAAAASSPASCCKELGLAAAAAWEQQGRSLFLAGVGPVRFLGPLAAVQLFRAPPAPPPQAEPATALEMVCKRKGAGVPACTPCKQPRCGCGGCGGGGGGGGGPAGGGASPPRPPDAGCCQAPEQPPPPLCPAPASPASECAPIVAAAGDTVRAGGTAPSSAQQQPESGDADCQEPPENPCDCHREPPPEIPDINQLPPSILLKIFSNLSLNERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNIIEINISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQWT

Target ORF information:

RefSeq Version	XM_006524600.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006524600.3

ORF Insert Sequence:

ATGGGCCACC TTCTCTCGAA GGAGCCGCGT AACCGCCCGA GCCAGAAGAG GCCTCGCTGC 
TGCAGCTGGT GTCGCCGCCG GCGCCCTCTC CTCAGACTGC CCCGCCGGGC TCTGGCCAAG 
GCGTCCCCGC AGCCCGCGGC GCCCCGGAGC CGGGACTGCT TCTTCCGCGG GCCCTGCATG 
CTCTGCTTCA TCGTGCACAG CCCCGGCGCG CCCGCCTCCG CCGGCCTAGA GGAGGAGCCG 
CCGCTCTCGC CACCGCCGCC GCCGCCGCGG GACGGGGCCT ACGCCGCCGT CTCCTCGCAG 
CACTTGGCGC GGCGCTACGC GGCCCTGGCC GCCGAGGACT GCGCCGCCGC CGCACGCCGC 
TTCCTGCTGT CCTCGGCCGC CGCCGCCGCC GCCGCTGCCT CGTCGCCCGC GTCCTGCTGC 
AAGGAGCTGG GGCTGGCCGC CGCCGCCGCC TGGGAGCAGC AGGGCCGGAG CCTCTTCCTG 
GCCGGCGTGG GGCCCGTGCG CTTCCTGGGA CCGCTGGCCG CCGTGCAGCT CTTCCGGGCA 
CCGCCGGCGC CGCCGCCGCA GGCCGAGCCC GCCACGGCCC TCGAGATGGT TTGCAAGCGG 
AAAGGGGCCG GGGTCCCCGC CTGCACCCCC TGCAAGCAGC CCCGTTGCGG CTGCGGGGGC 
TGCGGCGGGG GCGGCGGCGG CGGGGGAGGG CCCGCGGGAG GAGGTGCCTC GCCGCCGCGG 
CCGCCCGATG CCGGCTGCTG CCAGGCCCCG GAGCAGCCCC CGCCGCCGCT CTGCCCCGCG 
CCCGCCTCTC CCGCCTCAGA GTGTGCCCCC ATCGTGGCCG CCGCCGGGGA CACAGTCCGA 
GCCGGGGGCA CCGCCCCCTC GTCTGCCCAG CAGCAGCCCG AGAGCGGCGA CGCGGACTGT 
CAGGAGCCCC CCGAAAACCC CTGCGACTGT CACAGGGAGC CGCCCCCCGA GATCCCAGAC 
ATCAACCAAC TGCCGCCGTC CATCCTGCTT AAGATATTTT CCAATTTGTC CCTGAACGAA 
CGCTGCCTTT CTGCATCGTT GGTTTGCAAG TACTGGCGTG ACCTTTGCTT AGATTTCCAG 
TTTTGGAAGC AGCTGGACCT TAGTAGTCGT CAGCAGGTTA CTGATGAATT ATTGGAAAAA 
ATTGCCTCCA GAAGTCAGAA TATAATTGAG ATTAACATTT CTGATTGTCG AAGTCTGTCT 
GACAGTGGCG TGTGTGTCCT AGCATTTAAG TGTCCTGGAC TTCTTAGGTA TACAGCCTAC 
AGGTGTAAGC AGCTTTCTGA CACCTCAATC ATTGCGGTCG CGTCTCACTG CCCTTTACTG 
CAGAAAGTCC ACGTAGGCAA CCAGGACAAG CTCACCGATG AAGGACTTAA GCAGTGGACA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
The EMBO journal35(13)1400-16(2016 07)
Raducu M,Fung E,Serres S,Infante P,Barberis A,Fischer R,Bristow C,Th?z?nas ML,Finta C,Christianson JC,Buffa FM,Kessler BM,Sibson NR,Di Marcotullio L,Toftg?rd R,D'Angiolella V

Systematic analysis and nomenclature of mammalian F-box proteins.
Genes & development18(21)2573-80(2004 Nov)
Jin J,Cardozo T,Lovering RC,Elledge SJ,Pagano M,Harper JW

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

A family of mammalian F-box proteins.
Current biology : CB9(20)1180-2(1999 Oct)
Winston JT,Koepp DM,Zhu C,Elledge SJ,Harper JW

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Fbxl17 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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