Txnrd1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Txnrd1
Entrez Gene ID	50493
Full Name	thioredoxin reductase 1
Synonyms	TR,TR1,TrxR1
General protein information	Preferred Names thioredoxin reductase 1 Names thioredoxin reductase 1, cytoplasmic TR alpha thioredoxin reductase TR1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 C1
Summary	The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms. [provided by RefSeq, May 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001042523.1	NP_001035988.1	thioredoxin reductase 1, cytoplasmic isoform 2
NM_001042514.1	NP_001035979.1	thioredoxin reductase 1, cytoplasmic isoform 1
NM_015762.2	NP_056577.2	thioredoxin reductase 1, cytoplasmic isoform 1
NM_001042513.1	NP_001035978.1	thioredoxin reductase 1, cytoplasmic isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TXNRD1	NP_001116141.1
	TXNRD1	XP_002798903.1
Mus musculus (house mouse)	Txnrd1	NP_001035988.1
Arabidopsis thaliana (thale cress)	GR1	NP_001118688.1
Xenopus tropicalis (tropical clawed frog)	txnrd1	NP_001243400.1
Canis lupus familiaris (dog)	TXNRD1	NP_001116145.1
Bos taurus (cattle)	TXNRD1	NP_777050.1
Homo sapiens (human)	TXNRD1	NP_001087240.1
Rattus norvegicus (Norway rat)	Txnrd1	NP_113802.2
Gallus gallus (chicken)	TXNRD1	NP_001025933.2
Oryza sativa (rice)	Os02g0813500	NP_001048485.1

Gene Ontology
Bibliography

Related articles in PubMed

MiR-23-TrxR1 as a novel molecular axis in skeletal muscle differentiation.
Mercatelli N, Fittipaldi S, De Paola E, Dimauro I, Paronetto MP, Jackson MJ, Caporossi D
Scientific reports7(1)7219(2017 Aug)

Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes.
Osborne SA, Tonissen KF
BMC genomics210(2001)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Collectively, our results suggest that MsrA protects hepatocytes from APAP-induced cytotoxicity through the modulation of TXNRD1 expression.
Title: Methionine sulfoxide reductase A protects hepatocytes against acetaminophen-induced toxicity via regulation of thioredoxin reductase 1 expression.

The results demonstrate that DATS protects against oxidative stress-induced DNA damage and apoptosis in C2C12 cells in part through the activation of Nrf2-mediated TrxR1 induction via the ERK signaling pathway.
Title: Antioxidative effects of diallyl trisulfide on hydrogen peroxide-induced cytotoxicity through regulation of nuclear factor-E2-related factor-mediated thioredoxin reductase 1 expression in C2C12 skeletal muscle myoblast cells.

GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea; the thioredoxin/thioredoxin reductase system can probably operate as a functional backup for GSR.
Title: GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR.

TrxR1 represents a novel therapeutic target to prevent oxygen-mediated neonatal lung injury through Nrf2.
Title: Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nuclear Factor E2-Related Factor 2 Activation.

Considering the variable expression levels of Sep15 and TR1 found within the human population, our results provide insights into new roles of selenoproteins in cancer
Title: The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways.

The following Txnrd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Txnrd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu15601	NM_001042514.1 Latest version!	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu15601	NM_001042513.1 Latest version!	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu15601	NM_015762.2 Latest version!	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu15752	NM_001042523.1 Latest version!	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$363.30 $519.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Txnrd1 ( NM_001042514.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001035979.1 Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu15601
Clone ID Related Accession (Same CDS sequence)	NM_001042514.1 , NM_015762.2 , NM_001042513.1
Accession Version	NM_001042514.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Mus musculus(house mouse)
Product	thioredoxin reductase 1, cytoplasmic isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CX562215.1, AB027565.1 and CJ235434.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.107420.1, SRR1660819.157761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 10721726 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATGGCT CCAAAGATCC CCCTGGGTCC TATGACTTCG ACCTGATCAT CATTGGAGGA 
GGCTCAGGAG GACTGGCAGC AGCTAAGGAG GCAGCCAAAT TTGACAAGAA AGTGCTGGTC 
TTGGATTTTG TCACACCGAC TCCTCTTGGG ACCAGATGGG GTCTCGGAGG AACGTGTGTG 
AATGTGGGTT GCATACCTAA GAAGCTGATG CACCAGGCAG CTTTGCTCGG ACAAGCTCTG 
AAAGACTCGC GCAACTATGG CTGGAAAGTC GAAGACACAG TGAAGCATGA CTGGGAGAAA 
ATGACGGAAT CTGTGCAGAG TCACATCGGC TCGCTGAACT GGGGCTACCG CGTAGCTCTC 
CGGGAGAAAA AGGTCGTCTA TGAGAATGCT TACGGGAGGT TCATTGGTCC TCACAGGATT 
GTGGCGACAA ATAACAAAGG TAAAGAAAAA ATCTATTCAG CAGAGCGGTT CCTCATCGCC 
ACAGGTGAGA GGCCCCGCTA CCTGGGCATC CCTGGAGACA AAGAGTACTG CATCAGCAGT 
GATGATCTTT TCTCCTTGCC TTACTGCCCG GGGAAGACCC TAGTAGTTGG TGCATCCTAT 
GTCGCCTTGG AATGTGCAGG ATTTCTGGCT GGTATCGGCT TAGACGTCAC TGTAATGGTG 
CGGTCCATTC TCCTTAGAGG ATTTGACCAA GACATGGCCA ACAAAATCGG TGAACACATG 
GAAGAACATG GTATCAAGTT TATAAGGCAG TTCGTCCCAA CGAAAATTGA ACAGATCGAA 
GCAGGAACAC CAGGCCGACT CAGGGTGACT GCTCAATCCA CAAACAGCGA GGAGACCATA 
GAGGGCGAAT TTAACACAGT GTTGCTGGCG GTAGGAAGAG ATTCTTGTAC GAGAACTATT 
GGCTTAGAGA CCGTGGGCGT GAAGATAAAC GAAAAAACCG GAAAGATACC CGTCACGGAT 
GAAGAGCAGA CCAATGTGCC TTACATCTAC GCCATCGGTG ACATCCTGGA GGGGAAGCTA 
GAGCTGACTC CCGTAGCCAT CCAGGCGGGG AGATTGCTGG CTCAGAGGCT GTATGGAGGC 
TCCAATGTCA AATGTGACTA TGACAATGTC CCAACGACTG TATTTACTCC TTTGGAATAT 
GGCTGTTGTG GCCTCTCTGA AGAAAAAGCC GTAGAGAAAT TTGGGGAAGA AAATATTGAA 
GTTTACCATA GTTTCTTTTG GCCATTGGAA TGGACAGTCC CATCCCGGGA TAACAACAAA 
TGTTATGCAA AAATAATCTG CAACCTTAAA GACGATGAAC GTGTCGTGGG CTTCCACGTG 
CTGGGTCCAA ACGCTGGAGA GGTGACGCAG GGCTTTGCGG CTGCGCTCAA GTGTGGGCTG 
ACTAAGCAGC AGCTGGACAG CACCATCGGC ATCCACCCGG TCTGTGCAGA GATATTCACA 
ACGTTGTCAG TGACGAAGCG CTCTGGGGGA GACATCCTCC AGTCTGGCTG CTGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035979.1
CDS	327..1826
Translation	MNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGC*G

Target ORF information:

RefSeq Version	NM_001042514.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042514.1

ORF Insert Sequence:

ATGAATGGCT CCAAAGATCC CCCTGGGTCC TATGACTTCG ACCTGATCAT CATTGGAGGA 
GGCTCAGGAG GACTGGCAGC AGCTAAGGAG GCAGCCAAAT TTGACAAGAA AGTGCTGGTC 
TTGGATTTTG TCACACCGAC TCCTCTTGGG ACCAGATGGG GTCTCGGAGG AACGTGTGTG 
AATGTGGGTT GCATACCTAA GAAGCTGATG CACCAGGCAG CTTTGCTCGG ACAAGCTCTG 
AAAGACTCGC GCAACTATGG CTGGAAAGTC GAAGACACAG TGAAGCATGA CTGGGAGAAA 
ATGACGGAAT CTGTGCAGAG TCACATCGGC TCGCTGAACT GGGGCTACCG CGTAGCTCTC 
CGGGAGAAAA AGGTCGTCTA TGAGAATGCT TACGGGAGGT TCATTGGTCC TCACAGGATT 
GTGGCGACAA ATAACAAAGG TAAAGAAAAA ATCTATTCAG CAGAGCGGTT CCTCATCGCC 
ACAGGTGAGA GGCCCCGCTA CCTGGGCATC CCTGGAGACA AAGAGTACTG CATCAGCAGT 
GATGATCTTT TCTCCTTGCC TTACTGCCCG GGGAAGACCC TAGTAGTTGG TGCATCCTAT 
GTCGCCTTGG AATGTGCAGG ATTTCTGGCT GGTATCGGCT TAGACGTCAC TGTAATGGTG 
CGGTCCATTC TCCTTAGAGG ATTTGACCAA GACATGGCCA ACAAAATCGG TGAACACATG 
GAAGAACATG GTATCAAGTT TATAAGGCAG TTCGTCCCAA CGAAAATTGA ACAGATCGAA 
GCAGGAACAC CAGGCCGACT CAGGGTGACT GCTCAATCCA CAAACAGCGA GGAGACCATA 
GAGGGCGAAT TTAACACAGT GTTGCTGGCG GTAGGAAGAG ATTCTTGTAC GAGAACTATT 
GGCTTAGAGA CCGTGGGCGT GAAGATAAAC GAAAAAACCG GAAAGATACC CGTCACGGAT 
GAAGAGCAGA CCAATGTGCC TTACATCTAC GCCATCGGTG ACATCCTGGA GGGGAAGCTA 
GAGCTGACTC CCGTAGCCAT CCAGGCGGGG AGATTGCTGG CTCAGAGGCT GTATGGAGGC 
TCCAATGTCA AATGTGACTA TGACAATGTC CCAACGACTG TATTTACTCC TTTGGAATAT 
GGCTGTTGTG GCCTCTCTGA AGAAAAAGCC GTAGAGAAAT TTGGGGAAGA AAATATTGAA 
GTTTACCATA GTTTCTTTTG GCCATTGGAA TGGACAGTCC CATCCCGGGA TAACAACAAA 
TGTTATGCAA AAATAATCTG CAACCTTAAA GACGATGAAC GTGTCGTGGG CTTCCACGTG 
CTGGGTCCAA ACGCTGGAGA GGTGACGCAG GGCTTTGCGG CTGCGCTCAA GTGTGGGCTG 
ACTAAGCAGC AGCTGGACAG CACCATCGGC ATCCACCCGG TCTGTGCAGA GATATTCACA 
ACGTTGTCAG TGACGAAGCG CTCTGGGGGA GACATCCTCC AGTCTGGCTG CTGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Txnrd1 ( NM_015762.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_056577.2 Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu15601
Clone ID Related Accession (Same CDS sequence)	NM_001042514.1 , NM_015762.2 , NM_001042513.1
Accession Version	NM_015762.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Mus musculus(house mouse)
Product	thioredoxin reductase 1, cytoplasmic isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB027565.1 and CJ235434.1. On Jul 6, 2006 this sequence version replaced NM_015762.1. Transcript Variant: This variant (2) lacks a 5' non-coding exon; therefore, has a shorter 5' UTR compared to variant 1. Variants 1-3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK146125.1, AB027565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849377 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 10721726 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATGGCT CCAAAGATCC CCCTGGGTCC TATGACTTCG ACCTGATCAT CATTGGAGGA 
GGCTCAGGAG GACTGGCAGC AGCTAAGGAG GCAGCCAAAT TTGACAAGAA AGTGCTGGTC 
TTGGATTTTG TCACACCGAC TCCTCTTGGG ACCAGATGGG GTCTCGGAGG AACGTGTGTG 
AATGTGGGTT GCATACCTAA GAAGCTGATG CACCAGGCAG CTTTGCTCGG ACAAGCTCTG 
AAAGACTCGC GCAACTATGG CTGGAAAGTC GAAGACACAG TGAAGCATGA CTGGGAGAAA 
ATGACGGAAT CTGTGCAGAG TCACATCGGC TCGCTGAACT GGGGCTACCG CGTAGCTCTC 
CGGGAGAAAA AGGTCGTCTA TGAGAATGCT TACGGGAGGT TCATTGGTCC TCACAGGATT 
GTGGCGACAA ATAACAAAGG TAAAGAAAAA ATCTATTCAG CAGAGCGGTT CCTCATCGCC 
ACAGGTGAGA GGCCCCGCTA CCTGGGCATC CCTGGAGACA AAGAGTACTG CATCAGCAGT 
GATGATCTTT TCTCCTTGCC TTACTGCCCG GGGAAGACCC TAGTAGTTGG TGCATCCTAT 
GTCGCCTTGG AATGTGCAGG ATTTCTGGCT GGTATCGGCT TAGACGTCAC TGTAATGGTG 
CGGTCCATTC TCCTTAGAGG ATTTGACCAA GACATGGCCA ACAAAATCGG TGAACACATG 
GAAGAACATG GTATCAAGTT TATAAGGCAG TTCGTCCCAA CGAAAATTGA ACAGATCGAA 
GCAGGAACAC CAGGCCGACT CAGGGTGACT GCTCAATCCA CAAACAGCGA GGAGACCATA 
GAGGGCGAAT TTAACACAGT GTTGCTGGCG GTAGGAAGAG ATTCTTGTAC GAGAACTATT 
GGCTTAGAGA CCGTGGGCGT GAAGATAAAC GAAAAAACCG GAAAGATACC CGTCACGGAT 
GAAGAGCAGA CCAATGTGCC TTACATCTAC GCCATCGGTG ACATCCTGGA GGGGAAGCTA 
GAGCTGACTC CCGTAGCCAT CCAGGCGGGG AGATTGCTGG CTCAGAGGCT GTATGGAGGC 
TCCAATGTCA AATGTGACTA TGACAATGTC CCAACGACTG TATTTACTCC TTTGGAATAT 
GGCTGTTGTG GCCTCTCTGA AGAAAAAGCC GTAGAGAAAT TTGGGGAAGA AAATATTGAA 
GTTTACCATA GTTTCTTTTG GCCATTGGAA TGGACAGTCC CATCCCGGGA TAACAACAAA 
TGTTATGCAA AAATAATCTG CAACCTTAAA GACGATGAAC GTGTCGTGGG CTTCCACGTG 
CTGGGTCCAA ACGCTGGAGA GGTGACGCAG GGCTTTGCGG CTGCGCTCAA GTGTGGGCTG 
ACTAAGCAGC AGCTGGACAG CACCATCGGC ATCCACCCGG TCTGTGCAGA GATATTCACA 
ACGTTGTCAG TGACGAAGCG CTCTGGGGGA GACATCCTCC AGTCTGGCTG CTGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056577.2
CDS	132..1631
Translation	MNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGC*G

Target ORF information:

RefSeq Version	NM_015762.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015762.2

ORF Insert Sequence:

ATGAATGGCT CCAAAGATCC CCCTGGGTCC TATGACTTCG ACCTGATCAT CATTGGAGGA 
GGCTCAGGAG GACTGGCAGC AGCTAAGGAG GCAGCCAAAT TTGACAAGAA AGTGCTGGTC 
TTGGATTTTG TCACACCGAC TCCTCTTGGG ACCAGATGGG GTCTCGGAGG AACGTGTGTG 
AATGTGGGTT GCATACCTAA GAAGCTGATG CACCAGGCAG CTTTGCTCGG ACAAGCTCTG 
AAAGACTCGC GCAACTATGG CTGGAAAGTC GAAGACACAG TGAAGCATGA CTGGGAGAAA 
ATGACGGAAT CTGTGCAGAG TCACATCGGC TCGCTGAACT GGGGCTACCG CGTAGCTCTC 
CGGGAGAAAA AGGTCGTCTA TGAGAATGCT TACGGGAGGT TCATTGGTCC TCACAGGATT 
GTGGCGACAA ATAACAAAGG TAAAGAAAAA ATCTATTCAG CAGAGCGGTT CCTCATCGCC 
ACAGGTGAGA GGCCCCGCTA CCTGGGCATC CCTGGAGACA AAGAGTACTG CATCAGCAGT 
GATGATCTTT TCTCCTTGCC TTACTGCCCG GGGAAGACCC TAGTAGTTGG TGCATCCTAT 
GTCGCCTTGG AATGTGCAGG ATTTCTGGCT GGTATCGGCT TAGACGTCAC TGTAATGGTG 
CGGTCCATTC TCCTTAGAGG ATTTGACCAA GACATGGCCA ACAAAATCGG TGAACACATG 
GAAGAACATG GTATCAAGTT TATAAGGCAG TTCGTCCCAA CGAAAATTGA ACAGATCGAA 
GCAGGAACAC CAGGCCGACT CAGGGTGACT GCTCAATCCA CAAACAGCGA GGAGACCATA 
GAGGGCGAAT TTAACACAGT GTTGCTGGCG GTAGGAAGAG ATTCTTGTAC GAGAACTATT 
GGCTTAGAGA CCGTGGGCGT GAAGATAAAC GAAAAAACCG GAAAGATACC CGTCACGGAT 
GAAGAGCAGA CCAATGTGCC TTACATCTAC GCCATCGGTG ACATCCTGGA GGGGAAGCTA 
GAGCTGACTC CCGTAGCCAT CCAGGCGGGG AGATTGCTGG CTCAGAGGCT GTATGGAGGC 
TCCAATGTCA AATGTGACTA TGACAATGTC CCAACGACTG TATTTACTCC TTTGGAATAT 
GGCTGTTGTG GCCTCTCTGA AGAAAAAGCC GTAGAGAAAT TTGGGGAAGA AAATATTGAA 
GTTTACCATA GTTTCTTTTG GCCATTGGAA TGGACAGTCC CATCCCGGGA TAACAACAAA 
TGTTATGCAA AAATAATCTG CAACCTTAAA GACGATGAAC GTGTCGTGGG CTTCCACGTG 
CTGGGTCCAA ACGCTGGAGA GGTGACGCAG GGCTTTGCGG CTGCGCTCAA GTGTGGGCTG 
ACTAAGCAGC AGCTGGACAG CACCATCGGC ATCCACCCGG TCTGTGCAGA GATATTCACA 
ACGTTGTCAG TGACGAAGCG CTCTGGGGGA GACATCCTCC AGTCTGGCTG CTGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Txnrd1 ( NM_001042513.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001035978.1 Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu15601
Clone ID Related Accession (Same CDS sequence)	NM_001042514.1 , NM_015762.2 , NM_001042513.1
Accession Version	NM_001042513.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Mus musculus(house mouse)
Product	thioredoxin reductase 1, cytoplasmic isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CJ136679.1, AK149625.1, AB027565.1 and CJ235434.1. Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform 1. Variants 1-3 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7652917.755478.1, SRR7652917.723732.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 10721726 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATGGCT CCAAAGATCC CCCTGGGTCC TATGACTTCG ACCTGATCAT CATTGGAGGA 
GGCTCAGGAG GACTGGCAGC AGCTAAGGAG GCAGCCAAAT TTGACAAGAA AGTGCTGGTC 
TTGGATTTTG TCACACCGAC TCCTCTTGGG ACCAGATGGG GTCTCGGAGG AACGTGTGTG 
AATGTGGGTT GCATACCTAA GAAGCTGATG CACCAGGCAG CTTTGCTCGG ACAAGCTCTG 
AAAGACTCGC GCAACTATGG CTGGAAAGTC GAAGACACAG TGAAGCATGA CTGGGAGAAA 
ATGACGGAAT CTGTGCAGAG TCACATCGGC TCGCTGAACT GGGGCTACCG CGTAGCTCTC 
CGGGAGAAAA AGGTCGTCTA TGAGAATGCT TACGGGAGGT TCATTGGTCC TCACAGGATT 
GTGGCGACAA ATAACAAAGG TAAAGAAAAA ATCTATTCAG CAGAGCGGTT CCTCATCGCC 
ACAGGTGAGA GGCCCCGCTA CCTGGGCATC CCTGGAGACA AAGAGTACTG CATCAGCAGT 
GATGATCTTT TCTCCTTGCC TTACTGCCCG GGGAAGACCC TAGTAGTTGG TGCATCCTAT 
GTCGCCTTGG AATGTGCAGG ATTTCTGGCT GGTATCGGCT TAGACGTCAC TGTAATGGTG 
CGGTCCATTC TCCTTAGAGG ATTTGACCAA GACATGGCCA ACAAAATCGG TGAACACATG 
GAAGAACATG GTATCAAGTT TATAAGGCAG TTCGTCCCAA CGAAAATTGA ACAGATCGAA 
GCAGGAACAC CAGGCCGACT CAGGGTGACT GCTCAATCCA CAAACAGCGA GGAGACCATA 
GAGGGCGAAT TTAACACAGT GTTGCTGGCG GTAGGAAGAG ATTCTTGTAC GAGAACTATT 
GGCTTAGAGA CCGTGGGCGT GAAGATAAAC GAAAAAACCG GAAAGATACC CGTCACGGAT 
GAAGAGCAGA CCAATGTGCC TTACATCTAC GCCATCGGTG ACATCCTGGA GGGGAAGCTA 
GAGCTGACTC CCGTAGCCAT CCAGGCGGGG AGATTGCTGG CTCAGAGGCT GTATGGAGGC 
TCCAATGTCA AATGTGACTA TGACAATGTC CCAACGACTG TATTTACTCC TTTGGAATAT 
GGCTGTTGTG GCCTCTCTGA AGAAAAAGCC GTAGAGAAAT TTGGGGAAGA AAATATTGAA 
GTTTACCATA GTTTCTTTTG GCCATTGGAA TGGACAGTCC CATCCCGGGA TAACAACAAA 
TGTTATGCAA AAATAATCTG CAACCTTAAA GACGATGAAC GTGTCGTGGG CTTCCACGTG 
CTGGGTCCAA ACGCTGGAGA GGTGACGCAG GGCTTTGCGG CTGCGCTCAA GTGTGGGCTG 
ACTAAGCAGC AGCTGGACAG CACCATCGGC ATCCACCCGG TCTGTGCAGA GATATTCACA 
ACGTTGTCAG TGACGAAGCG CTCTGGGGGA GACATCCTCC AGTCTGGCTG CTGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035978.1
CDS	239..1738
Translation	MNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGC*G

Target ORF information:

RefSeq Version	NM_001042513.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042513.1

ORF Insert Sequence:

ATGAATGGCT CCAAAGATCC CCCTGGGTCC TATGACTTCG ACCTGATCAT CATTGGAGGA 
GGCTCAGGAG GACTGGCAGC AGCTAAGGAG GCAGCCAAAT TTGACAAGAA AGTGCTGGTC 
TTGGATTTTG TCACACCGAC TCCTCTTGGG ACCAGATGGG GTCTCGGAGG AACGTGTGTG 
AATGTGGGTT GCATACCTAA GAAGCTGATG CACCAGGCAG CTTTGCTCGG ACAAGCTCTG 
AAAGACTCGC GCAACTATGG CTGGAAAGTC GAAGACACAG TGAAGCATGA CTGGGAGAAA 
ATGACGGAAT CTGTGCAGAG TCACATCGGC TCGCTGAACT GGGGCTACCG CGTAGCTCTC 
CGGGAGAAAA AGGTCGTCTA TGAGAATGCT TACGGGAGGT TCATTGGTCC TCACAGGATT 
GTGGCGACAA ATAACAAAGG TAAAGAAAAA ATCTATTCAG CAGAGCGGTT CCTCATCGCC 
ACAGGTGAGA GGCCCCGCTA CCTGGGCATC CCTGGAGACA AAGAGTACTG CATCAGCAGT 
GATGATCTTT TCTCCTTGCC TTACTGCCCG GGGAAGACCC TAGTAGTTGG TGCATCCTAT 
GTCGCCTTGG AATGTGCAGG ATTTCTGGCT GGTATCGGCT TAGACGTCAC TGTAATGGTG 
CGGTCCATTC TCCTTAGAGG ATTTGACCAA GACATGGCCA ACAAAATCGG TGAACACATG 
GAAGAACATG GTATCAAGTT TATAAGGCAG TTCGTCCCAA CGAAAATTGA ACAGATCGAA 
GCAGGAACAC CAGGCCGACT CAGGGTGACT GCTCAATCCA CAAACAGCGA GGAGACCATA 
GAGGGCGAAT TTAACACAGT GTTGCTGGCG GTAGGAAGAG ATTCTTGTAC GAGAACTATT 
GGCTTAGAGA CCGTGGGCGT GAAGATAAAC GAAAAAACCG GAAAGATACC CGTCACGGAT 
GAAGAGCAGA CCAATGTGCC TTACATCTAC GCCATCGGTG ACATCCTGGA GGGGAAGCTA 
GAGCTGACTC CCGTAGCCAT CCAGGCGGGG AGATTGCTGG CTCAGAGGCT GTATGGAGGC 
TCCAATGTCA AATGTGACTA TGACAATGTC CCAACGACTG TATTTACTCC TTTGGAATAT 
GGCTGTTGTG GCCTCTCTGA AGAAAAAGCC GTAGAGAAAT TTGGGGAAGA AAATATTGAA 
GTTTACCATA GTTTCTTTTG GCCATTGGAA TGGACAGTCC CATCCCGGGA TAACAACAAA 
TGTTATGCAA AAATAATCTG CAACCTTAAA GACGATGAAC GTGTCGTGGG CTTCCACGTG 
CTGGGTCCAA ACGCTGGAGA GGTGACGCAG GGCTTTGCGG CTGCGCTCAA GTGTGGGCTG 
ACTAAGCAGC AGCTGGACAG CACCATCGGC ATCCACCCGG TCTGTGCAGA GATATTCACA 
ACGTTGTCAG TGACGAAGCG CTCTGGGGGA GACATCCTCC AGTCTGGCTG CTGAGGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Txnrd1 ( NM_001042523.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001035988.1 Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 4, mRNA.

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CloneID	OMu15752
Clone ID Related Accession (Same CDS sequence)	NM_001042523.1
Accession Version	NM_001042523.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Mus musculus(house mouse)
Product	thioredoxin reductase 1, cytoplasmic isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF333036.1, AB027565.1 and CJ235434.1. Transcript Variant: This variant (4) represents the use of an alternate upstream promoter, and contains 2 novel exons compared to variant 1. The encoded isoform (2) has a longer and distinct N-terminus, resulting from translation initiation at an alternate in-frame start codon, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF333036.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 10721726 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCAGTTG ATGACTGCTG GCTGTACTTC CCAGCTTCTC GAGGTAGAAC CTTTGTGCAG 
ACTGTCTGGG TGGCACCCAC TTGCCCCAAC TGTTGCTGGT TTCCAGGTTT TCTCCCTCCA 
GTCCCCCGGC CACCACATGT GCCCCGTGTG CTGCTGAGGG GCCCTCGTGG GGCTGTGCTT 
CCTGCTTCAC GTCCCTCCAA GACACTCCCC TCCTCATCCC AGACGCCCTG TCCTACTGAC 
CCCTGTATCT GCCCTCCACC CTCCACACCT GATAGTAGGC AGGAAAAAAA TACGCAATCT 
GAGCTGCCGA ACAAAAAAGG CCAACTTCAA AAGCTGCCAA CAATGAATGG CTCCAAAGAT 
CCCCCTGGGT CCTATGACTT CGACCTGATC ATCATTGGAG GAGGCTCAGG AGGACTGGCA 
GCAGCTAAGG AGGCAGCCAA ATTTGACAAG AAAGTGCTGG TCTTGGATTT TGTCACACCG 
ACTCCTCTTG GGACCAGATG GGGTCTCGGA GGAACGTGTG TGAATGTGGG TTGCATACCT 
AAGAAGCTGA TGCACCAGGC AGCTTTGCTC GGACAAGCTC TGAAAGACTC GCGCAACTAT 
GGCTGGAAAG TCGAAGACAC AGTGAAGCAT GACTGGGAGA AAATGACGGA ATCTGTGCAG 
AGTCACATCG GCTCGCTGAA CTGGGGCTAC CGCGTAGCTC TCCGGGAGAA AAAGGTCGTC 
TATGAGAATG CTTACGGGAG GTTCATTGGT CCTCACAGGA TTGTGGCGAC AAATAACAAA 
GGTAAAGAAA AAATCTATTC AGCAGAGCGG TTCCTCATCG CCACAGGTGA GAGGCCCCGC 
TACCTGGGCA TCCCTGGAGA CAAAGAGTAC TGCATCAGCA GTGATGATCT TTTCTCCTTG 
CCTTACTGCC CGGGGAAGAC CCTAGTAGTT GGTGCATCCT ATGTCGCCTT GGAATGTGCA 
GGATTTCTGG CTGGTATCGG CTTAGACGTC ACTGTAATGG TGCGGTCCAT TCTCCTTAGA 
GGATTTGACC AAGACATGGC CAACAAAATC GGTGAACACA TGGAAGAACA TGGTATCAAG 
TTTATAAGGC AGTTCGTCCC AACGAAAATT GAACAGATCG AAGCAGGAAC ACCAGGCCGA 
CTCAGGGTGA CTGCTCAATC CACAAACAGC GAGGAGACCA TAGAGGGCGA ATTTAACACA 
GTGTTGCTGG CGGTAGGAAG AGATTCTTGT ACGAGAACTA TTGGCTTAGA GACCGTGGGC 
GTGAAGATAA ACGAAAAAAC CGGAAAGATA CCCGTCACGG ATGAAGAGCA GACCAATGTG 
CCTTACATCT ACGCCATCGG TGACATCCTG GAGGGGAAGC TAGAGCTGAC TCCCGTAGCC 
ATCCAGGCGG GGAGATTGCT GGCTCAGAGG CTGTATGGAG GCTCCAATGT CAAATGTGAC 
TATGACAATG TCCCAACGAC TGTATTTACT CCTTTGGAAT ATGGCTGTTG TGGCCTCTCT 
GAAGAAAAAG CCGTAGAGAA ATTTGGGGAA GAAAATATTG AAGTTTACCA TAGTTTCTTT 
TGGCCATTGG AATGGACAGT CCCATCCCGG GATAACAACA AATGTTATGC AAAAATAATC 
TGCAACCTTA AAGACGATGA ACGTGTCGTG GGCTTCCACG TGCTGGGTCC AAACGCTGGA 
GAGGTGACGC AGGGCTTTGC GGCTGCGCTC AAGTGTGGGC TGACTAAGCA GCAGCTGGAC 
AGCACCATCG GCATCCACCC GGTCTGTGCA GAGATATTCA CAACGTTGTC AGTGACGAAG 
CGCTCTGGGG GAGACATCCT CCAGTCTGGC TGCTGAGGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035988.1
CDS	114..1955
Translation	MPVDDCWLYFPASRGRTFVQTVWVAPTCPNCCWFPGFLPPVPRPPHVPRVLLRGPRGAVLPASRPSKTLPSSSQTPCPTDPCICPPPSTPDSRQEKNTQSELPNKKGQLQKLPTMNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGC*G

Target ORF information:

RefSeq Version	NM_001042523.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus thioredoxin reductase 1 (Txnrd1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042523.1

ORF Insert Sequence:

ATGCCAGTTG ATGACTGCTG GCTGTACTTC CCAGCTTCTC GAGGTAGAAC CTTTGTGCAG 
ACTGTCTGGG TGGCACCCAC TTGCCCCAAC TGTTGCTGGT TTCCAGGTTT TCTCCCTCCA 
GTCCCCCGGC CACCACATGT GCCCCGTGTG CTGCTGAGGG GCCCTCGTGG GGCTGTGCTT 
CCTGCTTCAC GTCCCTCCAA GACACTCCCC TCCTCATCCC AGACGCCCTG TCCTACTGAC 
CCCTGTATCT GCCCTCCACC CTCCACACCT GATAGTAGGC AGGAAAAAAA TACGCAATCT 
GAGCTGCCGA ACAAAAAAGG CCAACTTCAA AAGCTGCCAA CAATGAATGG CTCCAAAGAT 
CCCCCTGGGT CCTATGACTT CGACCTGATC ATCATTGGAG GAGGCTCAGG AGGACTGGCA 
GCAGCTAAGG AGGCAGCCAA ATTTGACAAG AAAGTGCTGG TCTTGGATTT TGTCACACCG 
ACTCCTCTTG GGACCAGATG GGGTCTCGGA GGAACGTGTG TGAATGTGGG TTGCATACCT 
AAGAAGCTGA TGCACCAGGC AGCTTTGCTC GGACAAGCTC TGAAAGACTC GCGCAACTAT 
GGCTGGAAAG TCGAAGACAC AGTGAAGCAT GACTGGGAGA AAATGACGGA ATCTGTGCAG 
AGTCACATCG GCTCGCTGAA CTGGGGCTAC CGCGTAGCTC TCCGGGAGAA AAAGGTCGTC 
TATGAGAATG CTTACGGGAG GTTCATTGGT CCTCACAGGA TTGTGGCGAC AAATAACAAA 
GGTAAAGAAA AAATCTATTC AGCAGAGCGG TTCCTCATCG CCACAGGTGA GAGGCCCCGC 
TACCTGGGCA TCCCTGGAGA CAAAGAGTAC TGCATCAGCA GTGATGATCT TTTCTCCTTG 
CCTTACTGCC CGGGGAAGAC CCTAGTAGTT GGTGCATCCT ATGTCGCCTT GGAATGTGCA 
GGATTTCTGG CTGGTATCGG CTTAGACGTC ACTGTAATGG TGCGGTCCAT TCTCCTTAGA 
GGATTTGACC AAGACATGGC CAACAAAATC GGTGAACACA TGGAAGAACA TGGTATCAAG 
TTTATAAGGC AGTTCGTCCC AACGAAAATT GAACAGATCG AAGCAGGAAC ACCAGGCCGA 
CTCAGGGTGA CTGCTCAATC CACAAACAGC GAGGAGACCA TAGAGGGCGA ATTTAACACA 
GTGTTGCTGG CGGTAGGAAG AGATTCTTGT ACGAGAACTA TTGGCTTAGA GACCGTGGGC 
GTGAAGATAA ACGAAAAAAC CGGAAAGATA CCCGTCACGG ATGAAGAGCA GACCAATGTG 
CCTTACATCT ACGCCATCGG TGACATCCTG GAGGGGAAGC TAGAGCTGAC TCCCGTAGCC 
ATCCAGGCGG GGAGATTGCT GGCTCAGAGG CTGTATGGAG GCTCCAATGT CAAATGTGAC 
TATGACAATG TCCCAACGAC TGTATTTACT CCTTTGGAAT ATGGCTGTTG TGGCCTCTCT 
GAAGAAAAAG CCGTAGAGAA ATTTGGGGAA GAAAATATTG AAGTTTACCA TAGTTTCTTT 
TGGCCATTGG AATGGACAGT CCCATCCCGG GATAACAACA AATGTTATGC AAAAATAATC 
TGCAACCTTA AAGACGATGA ACGTGTCGTG GGCTTCCACG TGCTGGGTCC AAACGCTGGA 
GAGGTGACGC AGGGCTTTGC GGCTGCGCTC AAGTGTGGGC TGACTAAGCA GCAGCTGGAC 
AGCACCATCG GCATCCACCC GGTCTGTGCA GAGATATTCA CAACGTTGTC AGTGACGAAG 
CGCTCTGGGG GAGACATCCT CCAGTCTGGC TGCTGAGGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MiR-23-TrxR1 as a novel molecular axis in skeletal muscle differentiation.
Scientific reports7(1)7219(2017 Aug)
Mercatelli N,Fittipaldi S,De Paola E,Dimauro I,Paronetto MP,Jackson MJ,Caporossi D

Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes.
BMC genomics210(2001)
Osborne SA,Tonissen KF

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Txnrd1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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