Panx2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Panx2
Entrez Gene ID	406218
Full Name	pannexin 2
General protein information	Preferred Names pannexin 2 Names pannexin-2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 E3\|15

mRNA and Protein(s)

mRNA	Protein	Name
XM_006521139.1	XP_006521202.1	pannexin-2 isoform X1
NM_001002005.2	NP_001002005.2	pannexin-2
XM_006521139.2	XP_006521202.1	pannexin-2 isoform X1
XM_017316689.1	XP_017172178.1	pannexin-2 isoform X2
XM_017316689.2	XP_017172178.1	pannexin-2 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	PANX2	NP_443071.2
Xenopus tropicalis (tropical clawed frog)	LOC100486454	XP_002932244.1
	LOC720613	XP_001116218.2
Mus musculus (house mouse)	Panx2	NP_001002005.2
Pan troglodytes (chimpanzee)	PANX2	XP_001140508.1
Gallus gallus (chicken)	PANX2	XP_424545.3
Canis lupus familiaris (dog)	PANX2	XP_538316.4
Bos taurus (cattle)	PANX2	NP_001095695.1
Danio rerio (zebrafish)	panx2	NP_001243570.1
Rattus norvegicus (Norway rat)	Panx2	NP_955441.2

Gene Ontology
Bibliography

Related articles in PubMed

Pannexin-2-deficiency sensitizes pancreatic ?-cells to cytokine-induced apoptosis in?vitro and impairs glucose tolerance in?vivo.
Berchtold LA, Miani M, Diep TA, Madsen AN, Cigliola V, Colli M, Krivokapic JM, Pociot F, Eizirik DL, Meda P, Holst B, Billestrup N, St?rling J
Molecular and cellular endocrinology448108-121(2017 Jun)

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release.
Wang S, Chennupati R, Kaur H, Iring A, Wettschureck N, Offermanns S
The Journal of clinical investigation126(12)4527-4536(2016 Dec)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Panx2 is an important regulator of the insulin secretory capacity and apoptosis in pancreatic beta-cells.
Title: Pannexin-2-deficiency sensitizes pancreatic ?-cells to cytokine-induced apoptosis in?vitro and impairs glucose tolerance in?vivo.

It used overlap-extension cloning to create the first chimeric Panx, consisting of Panx2 with the Panx1 C-terminus (Panx2(Panx1CT)), to determine whether the Panx1 C-terminus influences the trafficking of Panx2.
Title: Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization.

In situ hybridization revealed that mRNAs for Panx1 and Panx2 were both expressed in the olfactory epithelium and olfactory bulb.
Title: Patterns of heterogeneous expression of pannexin 1 and pannexin 2 transcripts in the olfactory epithelium and olfactory bulb.

). Pannexin double-knockout mice (Px1(-/-) Px2(-/-)) were less impaired in parameters such as exploration, anxiety, sensorimotor function and behavioral symmetry.
Title: Functional outcome of pannexin-deficient mice after cerebral ischemia.

Px1 and Px2 underlie channel function in neurons and contribute to ischemic brain damage
Title: Pannexins in ischemia-induced neurodegeneration.

The following Panx2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Panx2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu79153	XM_017316689.2 Latest version!	Mus musculus pannexin 2 (Panx2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu10207	NM_001002005.2 Latest version!	Mus musculus pannexin 2 (Panx2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu51420	XM_006521139.2 Latest version!	Mus musculus pannexin 2 (Panx2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OMu51420	XM_006521139.1	Mus musculus pannexin 2 (Panx2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OMu79153	XM_017316689.1	Mus musculus pannexin 2 (Panx2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Panx2 ( XM_017316689.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017172178.1 Mus musculus pannexin 2 (Panx2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu79153
Clone ID Related Accession (Same CDS sequence)	XM_017316689.1 , XM_017316689.2
Accession Version	XM_017316689.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	pannexin-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCTCA TCATCCTAGT CAACCTCATC CACCTCTTCA TCTTCCGCAA GAGCAACTTC 
ATCTTCGACA AACTAAACAA GGTGGGTATC AAGACGCGCC GGCAGTGGCG CCGCTCGCAG 
TTCTGCGACA TCAACATCCT GGCCATGTTC TGTAACGAGA ACCGCGACCA CATCAAGTCG 
CTGAACCGGC TGGACTTCAT CACCAACGAG AGCGACCTCA TGTACGACAA TGTGGTGCGG 
CAGCTTCTGG CTGCCTTGGC TCAGTCTAAC CACGACACCA CGCCCACTGT GCGGGACTCT 
GGCATCCAGA CCGTGGACCC CAGCATCAAC CCTGCGGAGC CTGATGGTTC TGCTGAGCCA 
CCCGTGGTCA AGCGGCCCCG TAAGAAAATG AAGTGGATCC CCACCAGCAA CCCGCTGCCA 
CAGCCCTTCA AGGAGCAGCT GGCCATTATG CGCGTGGAAA ACAGCAAGAC TGAGAAGCCC 
AAGCCCGTGC GCAGGAAGAC AGCCACAGAC ACACTTATTG CCCCGCTGCT GGACGCTGGT 
GCCCGTGCTG CCCACCACTA CAAGGGCAGT GGAGGTGATT CAGGCCCCTC CTCTGCCCCG 
CCTGCTGCCT CTGAGAAAAA GCATACCCGC CACTTCTCCT TGGACGTGCA TCCCTATATC 
CTAGGTACCA AGAAGGCCAA GACTGAGGCG GTACCCCCTG CCCTACCAGC CTCCCGCAGC 
CAAGAAGGTG GCTTCCTGTC CCAGACAGAG GAATGTGGGC TGGGCCTAGC TGCAGCACCC 
ACCAAAGATG CTCCACTCCC CGAGAAGGAA ATCCCGTACC CCACAGAGCC TGCCCTGCCA 
GGGCTCCCAT CTGGGGGATC ATTCCATGTC TGCTCACCCC CCGCAGCCCC CGCCGCTGCT 
TCCCTGTCAC CAGGCAGTCT GGGCAAGGCT GACCCTCTCA CCATCCTGAG CCGGAACGCC 
ACTCACCCCC TGCTCCACAT CAGCACGCTG TATGAGGCCC GGGAAGAGGA GGAAGGAGGC 
CCCTGTGCCC CCTCAGACAT GGGCGACCTC CTCAGCATAC CCCCGCCCCA GCAGATCCTC 
ATCGCCACCT TCGAGGAGCC GAGAACAGTT GTCCTGTTTC CCAAGTGCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017172178.1
CDS	634..1767
Translation	MNLIILVNLIHLFIFRKSNFIFDKLNKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEPDGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENSKTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDSGPSSAPPAASEKKHTRHFSLDVHPYILGTKKAKTEAVPPALPASRSQEGGFLSQTEECGLGLAAAPTKDAPLPEKEIPYPTEPALPGLPSGGSFHVCSPPAAPAAASLSPGSLGKADPLTILSRNATHPLLHISTLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVLFPKCH

Target ORF information:

RefSeq Version	XM_017316689.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus pannexin 2 (Panx2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017316689.1

ORF Insert Sequence:

ATGAACCTCA TCATCCTAGT CAACCTCATC CACCTCTTCA TCTTCCGCAA GAGCAACTTC 
ATCTTCGACA AACTAAACAA GGTGGGTATC AAGACGCGCC GGCAGTGGCG CCGCTCGCAG 
TTCTGCGACA TCAACATCCT GGCCATGTTC TGTAACGAGA ACCGCGACCA CATCAAGTCG 
CTGAACCGGC TGGACTTCAT CACCAACGAG AGCGACCTCA TGTACGACAA TGTGGTGCGG 
CAGCTTCTGG CTGCCTTGGC TCAGTCTAAC CACGACACCA CGCCCACTGT GCGGGACTCT 
GGCATCCAGA CCGTGGACCC CAGCATCAAC CCTGCGGAGC CTGATGGTTC TGCTGAGCCA 
CCCGTGGTCA AGCGGCCCCG TAAGAAAATG AAGTGGATCC CCACCAGCAA CCCGCTGCCA 
CAGCCCTTCA AGGAGCAGCT GGCCATTATG CGCGTGGAAA ACAGCAAGAC TGAGAAGCCC 
AAGCCCGTGC GCAGGAAGAC AGCCACAGAC ACACTTATTG CCCCGCTGCT GGACGCTGGT 
GCCCGTGCTG CCCACCACTA CAAGGGCAGT GGAGGTGATT CAGGCCCCTC CTCTGCCCCG 
CCTGCTGCCT CTGAGAAAAA GCATACCCGC CACTTCTCCT TGGACGTGCA TCCCTATATC 
CTAGGTACCA AGAAGGCCAA GACTGAGGCG GTACCCCCTG CCCTACCAGC CTCCCGCAGC 
CAAGAAGGTG GCTTCCTGTC CCAGACAGAG GAATGTGGGC TGGGCCTAGC TGCAGCACCC 
ACCAAAGATG CTCCACTCCC CGAGAAGGAA ATCCCGTACC CCACAGAGCC TGCCCTGCCA 
GGGCTCCCAT CTGGGGGATC ATTCCATGTC TGCTCACCCC CCGCAGCCCC CGCCGCTGCT 
TCCCTGTCAC CAGGCAGTCT GGGCAAGGCT GACCCTCTCA CCATCCTGAG CCGGAACGCC 
ACTCACCCCC TGCTCCACAT CAGCACGCTG TATGAGGCCC GGGAAGAGGA GGAAGGAGGC 
CCCTGTGCCC CCTCAGACAT GGGCGACCTC CTCAGCATAC CCCCGCCCCA GCAGATCCTC 
ATCGCCACCT TCGAGGAGCC GAGAACAGTT GTCCTGTTTC CCAAGTGCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Panx2 ( XM_017316689.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017172178.1 Mus musculus pannexin 2 (Panx2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu79153
Clone ID Related Accession (Same CDS sequence)	XM_017316689.1 , XM_017316689.2
Accession Version	XM_017316689.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	pannexin-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017316689.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCTCA TCATCCTAGT CAACCTCATC CACCTCTTCA TCTTCCGCAA GAGCAACTTC 
ATCTTCGACA AACTAAACAA GGTGGGTATC AAGACGCGCC GGCAGTGGCG CCGCTCGCAG 
TTCTGCGACA TCAACATCCT GGCCATGTTC TGTAACGAGA ACCGCGACCA CATCAAGTCG 
CTGAACCGGC TGGACTTCAT CACCAACGAG AGCGACCTCA TGTACGACAA TGTGGTGCGG 
CAGCTTCTGG CTGCCTTGGC TCAGTCTAAC CACGACACCA CGCCCACTGT GCGGGACTCT 
GGCATCCAGA CCGTGGACCC CAGCATCAAC CCTGCGGAGC CTGATGGTTC TGCTGAGCCA 
CCCGTGGTCA AGCGGCCCCG TAAGAAAATG AAGTGGATCC CCACCAGCAA CCCGCTGCCA 
CAGCCCTTCA AGGAGCAGCT GGCCATTATG CGCGTGGAAA ACAGCAAGAC TGAGAAGCCC 
AAGCCCGTGC GCAGGAAGAC AGCCACAGAC ACACTTATTG CCCCGCTGCT GGACGCTGGT 
GCCCGTGCTG CCCACCACTA CAAGGGCAGT GGAGGTGATT CAGGCCCCTC CTCTGCCCCG 
CCTGCTGCCT CTGAGAAAAA GCATACCCGC CACTTCTCCT TGGACGTGCA TCCCTATATC 
CTAGGTACCA AGAAGGCCAA GACTGAGGCG GTACCCCCTG CCCTACCAGC CTCCCGCAGC 
CAAGAAGGTG GCTTCCTGTC CCAGACAGAG GAATGTGGGC TGGGCCTAGC TGCAGCACCC 
ACCAAAGATG CTCCACTCCC CGAGAAGGAA ATCCCGTACC CCACAGAGCC TGCCCTGCCA 
GGGCTCCCAT CTGGGGGATC ATTCCATGTC TGCTCACCCC CCGCAGCCCC CGCCGCTGCT 
TCCCTGTCAC CAGGCAGTCT GGGCAAGGCT GACCCTCTCA CCATCCTGAG CCGGAACGCC 
ACTCACCCCC TGCTCCACAT CAGCACGCTG TATGAGGCCC GGGAAGAGGA GGAAGGAGGC 
CCCTGTGCCC CCTCAGACAT GGGCGACCTC CTCAGCATAC CCCCGCCCCA GCAGATCCTC 
ATCGCCACCT TCGAGGAGCC GAGAACAGTT GTCCTGTTTC CCAAGTGCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017172178.1
CDS	1670..2803
Translation	MNLIILVNLIHLFIFRKSNFIFDKLNKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEPDGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENSKTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDSGPSSAPPAASEKKHTRHFSLDVHPYILGTKKAKTEAVPPALPASRSQEGGFLSQTEECGLGLAAAPTKDAPLPEKEIPYPTEPALPGLPSGGSFHVCSPPAAPAAASLSPGSLGKADPLTILSRNATHPLLHISTLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVLFPKCH

Target ORF information:

RefSeq Version	XM_017316689.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus pannexin 2 (Panx2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017316689.2

ORF Insert Sequence:

ATGAACCTCA TCATCCTAGT CAACCTCATC CACCTCTTCA TCTTCCGCAA GAGCAACTTC 
ATCTTCGACA AACTAAACAA GGTGGGTATC AAGACGCGCC GGCAGTGGCG CCGCTCGCAG 
TTCTGCGACA TCAACATCCT GGCCATGTTC TGTAACGAGA ACCGCGACCA CATCAAGTCG 
CTGAACCGGC TGGACTTCAT CACCAACGAG AGCGACCTCA TGTACGACAA TGTGGTGCGG 
CAGCTTCTGG CTGCCTTGGC TCAGTCTAAC CACGACACCA CGCCCACTGT GCGGGACTCT 
GGCATCCAGA CCGTGGACCC CAGCATCAAC CCTGCGGAGC CTGATGGTTC TGCTGAGCCA 
CCCGTGGTCA AGCGGCCCCG TAAGAAAATG AAGTGGATCC CCACCAGCAA CCCGCTGCCA 
CAGCCCTTCA AGGAGCAGCT GGCCATTATG CGCGTGGAAA ACAGCAAGAC TGAGAAGCCC 
AAGCCCGTGC GCAGGAAGAC AGCCACAGAC ACACTTATTG CCCCGCTGCT GGACGCTGGT 
GCCCGTGCTG CCCACCACTA CAAGGGCAGT GGAGGTGATT CAGGCCCCTC CTCTGCCCCG 
CCTGCTGCCT CTGAGAAAAA GCATACCCGC CACTTCTCCT TGGACGTGCA TCCCTATATC 
CTAGGTACCA AGAAGGCCAA GACTGAGGCG GTACCCCCTG CCCTACCAGC CTCCCGCAGC 
CAAGAAGGTG GCTTCCTGTC CCAGACAGAG GAATGTGGGC TGGGCCTAGC TGCAGCACCC 
ACCAAAGATG CTCCACTCCC CGAGAAGGAA ATCCCGTACC CCACAGAGCC TGCCCTGCCA 
GGGCTCCCAT CTGGGGGATC ATTCCATGTC TGCTCACCCC CCGCAGCCCC CGCCGCTGCT 
TCCCTGTCAC CAGGCAGTCT GGGCAAGGCT GACCCTCTCA CCATCCTGAG CCGGAACGCC 
ACTCACCCCC TGCTCCACAT CAGCACGCTG TATGAGGCCC GGGAAGAGGA GGAAGGAGGC 
CCCTGTGCCC CCTCAGACAT GGGCGACCTC CTCAGCATAC CCCCGCCCCA GCAGATCCTC 
ATCGCCACCT TCGAGGAGCC GAGAACAGTT GTCCTGTTTC CCAAGTGCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Panx2 ( NM_001002005.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001002005.2 Mus musculus pannexin 2 (Panx2), mRNA.

Price & Availability↑

CloneID	OMu10207
Clone ID Related Accession (Same CDS sequence)	NM_001002005.2
Accession Version	NM_001002005.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	pannexin-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ062100.1, BY727115.1, DQ093579.1 and BM942843.1. On Dec 21, 2007 this sequence version replaced NM_001002005.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ093579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCACCACC TCCTGGAGCA GTCGGCGGAC ATGGCGACCG CGCTGCTGGC GGGCGAGAAG 
CTGAGGGAGC TGATCCTGCC TGGCTCGCAG GACGACAAGG CGGGCGCGCT GGCCGCGCTG 
CTGCTGCAGC TCAAGCTGGA ACTGCCGTTC GACCGCGTGG TCACCATCGG CACCGTGCTG 
GTACCCATCC TGCTGGTCAC CCTGGTCTTC ACCAAGAACT TCGCAGAGGA ACCAATTTAC 
TGTTATACTC CGCACAACTT CACCCGTGAT CAGGCGCTGT ACGCCCGCGG CTACTGCTGG 
ACAGAGCTGC GGGACGCGCT GCCCGGCGTG GATGCCAGCC TCTGGCCATC GTTGTTTGAG 
CACAAGTTCC TGCCCTACGC GCTGCTGGCC TTTGCCGCCA TCATGTATGT GCCCGCGCTG 
GGCTGGGAGT TCCTCGCCTC CACGCGCCTC ACCTCGGAGC TCAACTTCCT TCTTCAGGAG 
ATCGACAACT GCTACCACCG AGCGGCCGAA GGTCGCGCAC CCAAGATTGA GAAGCAGATC 
CAGTCCAAGG GGCCCGGCAT CACGGAGCGC GAGAAGCGAG AGATCATTGA GAACGCCGAG 
AAGGAGAAGA GCCCGGAGCA GAATCTGTTT GAGAAGTACC TGGAACGCCG GGGCCGCAGC 
AACTTCCTGG CCAAGCTGTA CTTGGCACGG CACGTCCTGA TCCTGCTGCT CAGCGTGGTG 
CCCATCTCCT ACCTATGCAC ATACTACGCC ACCCAGAAGC AGAACGAGTT CACCTGTGCC 
CTGGGCGCCT CACCTGACGG GCCGGTGGGT AGCGCTGGGC CCACGGTGCG CGTCAGCTGT 
AAGCTACCGT CTGTGCAGCT GCAGCGGATC ATTGCAGGTG TGGACATCGT CTTGCTCTGC 
TTCATGAACC TCATCATCCT AGTCAACCTC ATCCACCTCT TCATCTTCCG CAAGAGCAAC 
TTCATCTTCG ACAAACTAAA CAAGGTGGGT ATCAAGACGC GCCGGCAGTG GCGCCGCTCG 
CAGTTCTGCG ACATCAACAT CCTGGCCATG TTCTGTAACG AGAACCGCGA CCACATCAAG 
TCGCTGAACC GGCTGGACTT CATCACCAAC GAGAGCGACC TCATGTACGA CAATGTGGTG 
CGGCAGCTTC TGGCTGCCTT GGCTCAGTCT AACCACGACA CCACGCCCAC TGTGCGGGAC 
TCTGGCATCC AGACCGTGGA CCCCAGCATC AACCCTGCGG AGCCTGATGG TTCTGCTGAG 
CCACCCGTGG TCAAGCGGCC CCGTAAGAAA ATGAAGTGGA TCCCCACCAG CAACCCGCTG 
CCACAGCCCT TCAAGGAGCA GCTGGCCATT ATGCGCGTGG AAAACAGCAA GACTGAGAAG 
CCCAAGCCCG TGCGCAGGAA GACAGCCACA GACACACTTA TTGCCCCGCT GCTGGACGCT 
GGTGCCCGTG CTGCCCACCA CTACAAGGGC AGTGGAGGTG ATTCAGGCCC CTCCTCTGCC 
CCGCCTGCTG CCTCTGAGAA AAAGCATACC CGCCACTTCT CCTTGGACGT GCATCCCTAT 
ATCCTAGGTA CCAAGAAGGC CAAGACTGAG GCGGTACCCC CTGCCCTACC AGCCTCCCGC 
AGCCAAGAAG GTGGCTTCCT GTCCCAGACA GAGGAATGTG GGCTGGGCCT AGCTGCAGCA 
CCCACCAAAG ATGCTCCACT CCCCGAGAAG GAAATCCCGT ACCCCACAGA GCCTGCCCTG 
CCAGGGCTCC CATCTGGGGG ATCATTCCAT GTCTGCTCAC CCCCCGCAGC CCCCGCCGCT 
GCTTCCCTGT CACCAGGCAG TCTGGGCAAG GCTGACCCTC TCACCATCCT GAGCCGGAAC 
GCCACTCACC CCCTGCTCCA CATCAGCACG CTGTATGAGG CCCGGGAAGA GGAGGAAGGA 
GGCCCCTGTG CCCCCTCAGA CATGGGCGAC CTCCTCAGCA TACCCCCGCC CCAGCAGATC 
CTCATCGCCA CCTTCGAGGA GCCGAGAACA GTTGTGAGTA CTGTGGAGTT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002005.2
CDS	349..2382
Translation	MHHLLEQSADMATALLAGEKLRELILPGSQDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSVVPISYLCTYYATQKQNEFTCALGASPDGPVGSAGPTVRVSCKLPSVQLQRIIAGVDIVLLCFMNLIILVNLIHLFIFRKSNFIFDKLNKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEPDGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENSKTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDSGPSSAPPAASEKKHTRHFSLDVHPYILGTKKAKTEAVPPALPASRSQEGGFLSQTEECGLGLAAAPTKDAPLPEKEIPYPTEPALPGLPSGGSFHVCSPPAAPAAASLSPGSLGKADPLTILSRNATHPLLHISTLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVSTVEF

Target ORF information:

RefSeq Version	NM_001002005.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus pannexin 2 (Panx2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002005.2

ORF Insert Sequence:

ATGCACCACC TCCTGGAGCA GTCGGCGGAC ATGGCGACCG CGCTGCTGGC GGGCGAGAAG 
CTGAGGGAGC TGATCCTGCC TGGCTCGCAG GACGACAAGG CGGGCGCGCT GGCCGCGCTG 
CTGCTGCAGC TCAAGCTGGA ACTGCCGTTC GACCGCGTGG TCACCATCGG CACCGTGCTG 
GTACCCATCC TGCTGGTCAC CCTGGTCTTC ACCAAGAACT TCGCAGAGGA ACCAATTTAC 
TGTTATACTC CGCACAACTT CACCCGTGAT CAGGCGCTGT ACGCCCGCGG CTACTGCTGG 
ACAGAGCTGC GGGACGCGCT GCCCGGCGTG GATGCCAGCC TCTGGCCATC GTTGTTTGAG 
CACAAGTTCC TGCCCTACGC GCTGCTGGCC TTTGCCGCCA TCATGTATGT GCCCGCGCTG 
GGCTGGGAGT TCCTCGCCTC CACGCGCCTC ACCTCGGAGC TCAACTTCCT TCTTCAGGAG 
ATCGACAACT GCTACCACCG AGCGGCCGAA GGTCGCGCAC CCAAGATTGA GAAGCAGATC 
CAGTCCAAGG GGCCCGGCAT CACGGAGCGC GAGAAGCGAG AGATCATTGA GAACGCCGAG 
AAGGAGAAGA GCCCGGAGCA GAATCTGTTT GAGAAGTACC TGGAACGCCG GGGCCGCAGC 
AACTTCCTGG CCAAGCTGTA CTTGGCACGG CACGTCCTGA TCCTGCTGCT CAGCGTGGTG 
CCCATCTCCT ACCTATGCAC ATACTACGCC ACCCAGAAGC AGAACGAGTT CACCTGTGCC 
CTGGGCGCCT CACCTGACGG GCCGGTGGGT AGCGCTGGGC CCACGGTGCG CGTCAGCTGT 
AAGCTACCGT CTGTGCAGCT GCAGCGGATC ATTGCAGGTG TGGACATCGT CTTGCTCTGC 
TTCATGAACC TCATCATCCT AGTCAACCTC ATCCACCTCT TCATCTTCCG CAAGAGCAAC 
TTCATCTTCG ACAAACTAAA CAAGGTGGGT ATCAAGACGC GCCGGCAGTG GCGCCGCTCG 
CAGTTCTGCG ACATCAACAT CCTGGCCATG TTCTGTAACG AGAACCGCGA CCACATCAAG 
TCGCTGAACC GGCTGGACTT CATCACCAAC GAGAGCGACC TCATGTACGA CAATGTGGTG 
CGGCAGCTTC TGGCTGCCTT GGCTCAGTCT AACCACGACA CCACGCCCAC TGTGCGGGAC 
TCTGGCATCC AGACCGTGGA CCCCAGCATC AACCCTGCGG AGCCTGATGG TTCTGCTGAG 
CCACCCGTGG TCAAGCGGCC CCGTAAGAAA ATGAAGTGGA TCCCCACCAG CAACCCGCTG 
CCACAGCCCT TCAAGGAGCA GCTGGCCATT ATGCGCGTGG AAAACAGCAA GACTGAGAAG 
CCCAAGCCCG TGCGCAGGAA GACAGCCACA GACACACTTA TTGCCCCGCT GCTGGACGCT 
GGTGCCCGTG CTGCCCACCA CTACAAGGGC AGTGGAGGTG ATTCAGGCCC CTCCTCTGCC 
CCGCCTGCTG CCTCTGAGAA AAAGCATACC CGCCACTTCT CCTTGGACGT GCATCCCTAT 
ATCCTAGGTA CCAAGAAGGC CAAGACTGAG GCGGTACCCC CTGCCCTACC AGCCTCCCGC 
AGCCAAGAAG GTGGCTTCCT GTCCCAGACA GAGGAATGTG GGCTGGGCCT AGCTGCAGCA 
CCCACCAAAG ATGCTCCACT CCCCGAGAAG GAAATCCCGT ACCCCACAGA GCCTGCCCTG 
CCAGGGCTCC CATCTGGGGG ATCATTCCAT GTCTGCTCAC CCCCCGCAGC CCCCGCCGCT 
GCTTCCCTGT CACCAGGCAG TCTGGGCAAG GCTGACCCTC TCACCATCCT GAGCCGGAAC 
GCCACTCACC CCCTGCTCCA CATCAGCACG CTGTATGAGG CCCGGGAAGA GGAGGAAGGA 
GGCCCCTGTG CCCCCTCAGA CATGGGCGAC CTCCTCAGCA TACCCCCGCC CCAGCAGATC 
CTCATCGCCA CCTTCGAGGA GCCGAGAACA GTTGTGAGTA CTGTGGAGTT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Panx2 ( XM_006521139.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521202.1 Mus musculus pannexin 2 (Panx2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51420
Clone ID Related Accession (Same CDS sequence)	XM_006521139.1 , XM_006521139.2
Accession Version	XM_006521139.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	pannexin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACCACC TCCTGGAGCA GTCGGCGGAC ATGGCGACCG CGCTGCTGGC GGGCGAGAAG 
CTGAGGGAGC TGATCCTGCC TGGCTCGCAG GACGACAAGG CGGGCGCGCT GGCCGCGCTG 
CTGCTGCAGC TCAAGCTGGA ACTGCCGTTC GACCGCGTGG TCACCATCGG CACCGTGCTG 
GTACCCATCC TGCTGGTCAC CCTGGTCTTC ACCAAGAACT TCGCAGAGGA ACCAATTTAC 
TGTTATACTC CGCACAACTT CACCCGTGAT CAGGCGCTGT ACGCCCGCGG CTACTGCTGG 
ACAGAGCTGC GGGACGCGCT GCCCGGCGTG GATGCCAGCC TCTGGCCATC GTTGTTTGAG 
CACAAGTTCC TGCCCTACGC GCTGCTGGCC TTTGCCGCCA TCATGTATGT GCCCGCGCTG 
GGCTGGGAGT TCCTCGCCTC CACGCGCCTC ACCTCGGAGC TCAACTTCCT TCTTCAGGAG 
ATCGACAACT GCTACCACCG AGCGGCCGAA GGTCGCGCAC CCAAGATTGA GAAGCAGATC 
CAGTCCAAGG GGCCCGGCAT CACGGAGCGC GAGAAGCGAG AGATCATTGA GAACGCCGAG 
AAGGAGAAGA GCCCGGAGCA GAATCTGTTT GAGAAGTACC TGGAACGCCG GGGCCGCAGC 
AACTTCCTGG CCAAGCTGTA CTTGGCACGG CACGTCCTGA TCCTGCTGCT CAGCGTGGTG 
CCCATCTCCT ACCTATGCAC ATACTACGCC ACCCAGAAGC AGAACGAGTT CACCTGTGCC 
CTGGGCGCCT CACCTGACGG GCCGGTGGGT AGCGCTGGGC CCACGGTGCG CGTCAGCTGT 
AAGCTACCGT CTGTGCAGCT GCAGCGGATC ATTGCAGGTG TGGACATCGT CTTGCTCTGC 
TTCATGAACC TCATCATCCT AGTCAACCTC ATCCACCTCT TCATCTTCCG CAAGAGCAAC 
TTCATCTTCG ACAAACTAAA CAAGGTGGGT ATCAAGACGC GCCGGCAGTG GCGCCGCTCG 
CAGTTCTGCG ACATCAACAT CCTGGCCATG TTCTGTAACG AGAACCGCGA CCACATCAAG 
TCGCTGAACC GGCTGGACTT CATCACCAAC GAGAGCGACC TCATGTACGA CAATGTGGTG 
CGGCAGCTTC TGGCTGCCTT GGCTCAGTCT AACCACGACA CCACGCCCAC TGTGCGGGAC 
TCTGGCATCC AGACCGTGGA CCCCAGCATC AACCCTGCGG AGCCTGATGG TTCTGCTGAG 
CCACCCGTGG TCAAGCGGCC CCGTAAGAAA ATGAAGTGGA TCCCCACCAG CAACCCGCTG 
CCACAGCCCT TCAAGGAGCA GCTGGCCATT ATGCGCGTGG AAAACAGCAA GACTGAGAAG 
CCCAAGCCCG TGCGCAGGAA GACAGCCACA GACACACTTA TTGCCCCGCT GCTGGACGCT 
GGTGCCCGTG CTGCCCACCA CTACAAGGGC AGTGGAGGTG ATTCAGGCCC CTCCTCTGCC 
CCGCCTGCTG CCTCTGAGAA AAAGCATACC CGCCACTTCT CCTTGGACGT GCATCCCTAT 
ATCCTAGGTA CCAAGAAGGC CAAGACTGAG GCGGTACCCC CTGCCCTACC AGCCTCCCGC 
AGCCAAGAAG GTGGCTTCCT GTCCCAGACA GAGGAATGTG GGCTGGGCCT AGCTGCAGCA 
CCCACCAAAG ATGCTCCACT CCCCGAGAAG GAAATCCCGT ACCCCACAGA GCCTGCCCTG 
CCAGGGCTCC CATCTGGGGG ATCATTCCAT GTCTGCTCAC CCCCCGCAGC CCCCGCCGCT 
GCTTCCCTGT CACCAGGCAG TCTGGGCAAG GCTGACCCTC TCACCATCCT GAGCCGGAAC 
GCCACTCACC CCCTGCTCCA CATCAGCACG CTGTATGAGG CCCGGGAAGA GGAGGAAGGA 
GGCCCCTGTG CCCCCTCAGA CATGGGCGAC CTCCTCAGCA TACCCCCGCC CCAGCAGATC 
CTCATCGCCA CCTTCGAGGA GCCGAGAACA GTTGTCCTGT TTCCCAAGTG CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521202.1
CDS	344..2380
Translation	MHHLLEQSADMATALLAGEKLRELILPGSQDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSVVPISYLCTYYATQKQNEFTCALGASPDGPVGSAGPTVRVSCKLPSVQLQRIIAGVDIVLLCFMNLIILVNLIHLFIFRKSNFIFDKLNKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEPDGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENSKTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDSGPSSAPPAASEKKHTRHFSLDVHPYILGTKKAKTEAVPPALPASRSQEGGFLSQTEECGLGLAAAPTKDAPLPEKEIPYPTEPALPGLPSGGSFHVCSPPAAPAAASLSPGSLGKADPLTILSRNATHPLLHISTLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVLFPKCH

Target ORF information:

RefSeq Version	XM_006521139.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus pannexin 2 (Panx2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521139.1

ORF Insert Sequence:

ATGCACCACC TCCTGGAGCA GTCGGCGGAC ATGGCGACCG CGCTGCTGGC GGGCGAGAAG 
CTGAGGGAGC TGATCCTGCC TGGCTCGCAG GACGACAAGG CGGGCGCGCT GGCCGCGCTG 
CTGCTGCAGC TCAAGCTGGA ACTGCCGTTC GACCGCGTGG TCACCATCGG CACCGTGCTG 
GTACCCATCC TGCTGGTCAC CCTGGTCTTC ACCAAGAACT TCGCAGAGGA ACCAATTTAC 
TGTTATACTC CGCACAACTT CACCCGTGAT CAGGCGCTGT ACGCCCGCGG CTACTGCTGG 
ACAGAGCTGC GGGACGCGCT GCCCGGCGTG GATGCCAGCC TCTGGCCATC GTTGTTTGAG 
CACAAGTTCC TGCCCTACGC GCTGCTGGCC TTTGCCGCCA TCATGTATGT GCCCGCGCTG 
GGCTGGGAGT TCCTCGCCTC CACGCGCCTC ACCTCGGAGC TCAACTTCCT TCTTCAGGAG 
ATCGACAACT GCTACCACCG AGCGGCCGAA GGTCGCGCAC CCAAGATTGA GAAGCAGATC 
CAGTCCAAGG GGCCCGGCAT CACGGAGCGC GAGAAGCGAG AGATCATTGA GAACGCCGAG 
AAGGAGAAGA GCCCGGAGCA GAATCTGTTT GAGAAGTACC TGGAACGCCG GGGCCGCAGC 
AACTTCCTGG CCAAGCTGTA CTTGGCACGG CACGTCCTGA TCCTGCTGCT CAGCGTGGTG 
CCCATCTCCT ACCTATGCAC ATACTACGCC ACCCAGAAGC AGAACGAGTT CACCTGTGCC 
CTGGGCGCCT CACCTGACGG GCCGGTGGGT AGCGCTGGGC CCACGGTGCG CGTCAGCTGT 
AAGCTACCGT CTGTGCAGCT GCAGCGGATC ATTGCAGGTG TGGACATCGT CTTGCTCTGC 
TTCATGAACC TCATCATCCT AGTCAACCTC ATCCACCTCT TCATCTTCCG CAAGAGCAAC 
TTCATCTTCG ACAAACTAAA CAAGGTGGGT ATCAAGACGC GCCGGCAGTG GCGCCGCTCG 
CAGTTCTGCG ACATCAACAT CCTGGCCATG TTCTGTAACG AGAACCGCGA CCACATCAAG 
TCGCTGAACC GGCTGGACTT CATCACCAAC GAGAGCGACC TCATGTACGA CAATGTGGTG 
CGGCAGCTTC TGGCTGCCTT GGCTCAGTCT AACCACGACA CCACGCCCAC TGTGCGGGAC 
TCTGGCATCC AGACCGTGGA CCCCAGCATC AACCCTGCGG AGCCTGATGG TTCTGCTGAG 
CCACCCGTGG TCAAGCGGCC CCGTAAGAAA ATGAAGTGGA TCCCCACCAG CAACCCGCTG 
CCACAGCCCT TCAAGGAGCA GCTGGCCATT ATGCGCGTGG AAAACAGCAA GACTGAGAAG 
CCCAAGCCCG TGCGCAGGAA GACAGCCACA GACACACTTA TTGCCCCGCT GCTGGACGCT 
GGTGCCCGTG CTGCCCACCA CTACAAGGGC AGTGGAGGTG ATTCAGGCCC CTCCTCTGCC 
CCGCCTGCTG CCTCTGAGAA AAAGCATACC CGCCACTTCT CCTTGGACGT GCATCCCTAT 
ATCCTAGGTA CCAAGAAGGC CAAGACTGAG GCGGTACCCC CTGCCCTACC AGCCTCCCGC 
AGCCAAGAAG GTGGCTTCCT GTCCCAGACA GAGGAATGTG GGCTGGGCCT AGCTGCAGCA 
CCCACCAAAG ATGCTCCACT CCCCGAGAAG GAAATCCCGT ACCCCACAGA GCCTGCCCTG 
CCAGGGCTCC CATCTGGGGG ATCATTCCAT GTCTGCTCAC CCCCCGCAGC CCCCGCCGCT 
GCTTCCCTGT CACCAGGCAG TCTGGGCAAG GCTGACCCTC TCACCATCCT GAGCCGGAAC 
GCCACTCACC CCCTGCTCCA CATCAGCACG CTGTATGAGG CCCGGGAAGA GGAGGAAGGA 
GGCCCCTGTG CCCCCTCAGA CATGGGCGAC CTCCTCAGCA TACCCCCGCC CCAGCAGATC 
CTCATCGCCA CCTTCGAGGA GCCGAGAACA GTTGTCCTGT TTCCCAAGTG CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Panx2 ( XM_006521139.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521202.1 Mus musculus pannexin 2 (Panx2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51420
Clone ID Related Accession (Same CDS sequence)	XM_006521139.1 , XM_006521139.2
Accession Version	XM_006521139.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	pannexin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006521139.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACCACC TCCTGGAGCA GTCGGCGGAC ATGGCGACCG CGCTGCTGGC GGGCGAGAAG 
CTGAGGGAGC TGATCCTGCC TGGCTCGCAG GACGACAAGG CGGGCGCGCT GGCCGCGCTG 
CTGCTGCAGC TCAAGCTGGA ACTGCCGTTC GACCGCGTGG TCACCATCGG CACCGTGCTG 
GTACCCATCC TGCTGGTCAC CCTGGTCTTC ACCAAGAACT TCGCAGAGGA ACCAATTTAC 
TGTTATACTC CGCACAACTT CACCCGTGAT CAGGCGCTGT ACGCCCGCGG CTACTGCTGG 
ACAGAGCTGC GGGACGCGCT GCCCGGCGTG GATGCCAGCC TCTGGCCATC GTTGTTTGAG 
CACAAGTTCC TGCCCTACGC GCTGCTGGCC TTTGCCGCCA TCATGTATGT GCCCGCGCTG 
GGCTGGGAGT TCCTCGCCTC CACGCGCCTC ACCTCGGAGC TCAACTTCCT TCTTCAGGAG 
ATCGACAACT GCTACCACCG AGCGGCCGAA GGTCGCGCAC CCAAGATTGA GAAGCAGATC 
CAGTCCAAGG GGCCCGGCAT CACGGAGCGC GAGAAGCGAG AGATCATTGA GAACGCCGAG 
AAGGAGAAGA GCCCGGAGCA GAATCTGTTT GAGAAGTACC TGGAACGCCG GGGCCGCAGC 
AACTTCCTGG CCAAGCTGTA CTTGGCACGG CACGTCCTGA TCCTGCTGCT CAGCGTGGTG 
CCCATCTCCT ACCTATGCAC ATACTACGCC ACCCAGAAGC AGAACGAGTT CACCTGTGCC 
CTGGGCGCCT CACCTGACGG GCCGGTGGGT AGCGCTGGGC CCACGGTGCG CGTCAGCTGT 
AAGCTACCGT CTGTGCAGCT GCAGCGGATC ATTGCAGGTG TGGACATCGT CTTGCTCTGC 
TTCATGAACC TCATCATCCT AGTCAACCTC ATCCACCTCT TCATCTTCCG CAAGAGCAAC 
TTCATCTTCG ACAAACTAAA CAAGGTGGGT ATCAAGACGC GCCGGCAGTG GCGCCGCTCG 
CAGTTCTGCG ACATCAACAT CCTGGCCATG TTCTGTAACG AGAACCGCGA CCACATCAAG 
TCGCTGAACC GGCTGGACTT CATCACCAAC GAGAGCGACC TCATGTACGA CAATGTGGTG 
CGGCAGCTTC TGGCTGCCTT GGCTCAGTCT AACCACGACA CCACGCCCAC TGTGCGGGAC 
TCTGGCATCC AGACCGTGGA CCCCAGCATC AACCCTGCGG AGCCTGATGG TTCTGCTGAG 
CCACCCGTGG TCAAGCGGCC CCGTAAGAAA ATGAAGTGGA TCCCCACCAG CAACCCGCTG 
CCACAGCCCT TCAAGGAGCA GCTGGCCATT ATGCGCGTGG AAAACAGCAA GACTGAGAAG 
CCCAAGCCCG TGCGCAGGAA GACAGCCACA GACACACTTA TTGCCCCGCT GCTGGACGCT 
GGTGCCCGTG CTGCCCACCA CTACAAGGGC AGTGGAGGTG ATTCAGGCCC CTCCTCTGCC 
CCGCCTGCTG CCTCTGAGAA AAAGCATACC CGCCACTTCT CCTTGGACGT GCATCCCTAT 
ATCCTAGGTA CCAAGAAGGC CAAGACTGAG GCGGTACCCC CTGCCCTACC AGCCTCCCGC 
AGCCAAGAAG GTGGCTTCCT GTCCCAGACA GAGGAATGTG GGCTGGGCCT AGCTGCAGCA 
CCCACCAAAG ATGCTCCACT CCCCGAGAAG GAAATCCCGT ACCCCACAGA GCCTGCCCTG 
CCAGGGCTCC CATCTGGGGG ATCATTCCAT GTCTGCTCAC CCCCCGCAGC CCCCGCCGCT 
GCTTCCCTGT CACCAGGCAG TCTGGGCAAG GCTGACCCTC TCACCATCCT GAGCCGGAAC 
GCCACTCACC CCCTGCTCCA CATCAGCACG CTGTATGAGG CCCGGGAAGA GGAGGAAGGA 
GGCCCCTGTG CCCCCTCAGA CATGGGCGAC CTCCTCAGCA TACCCCCGCC CCAGCAGATC 
CTCATCGCCA CCTTCGAGGA GCCGAGAACA GTTGTCCTGT TTCCCAAGTG CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521202.1
CDS	1018..3054
Translation	MHHLLEQSADMATALLAGEKLRELILPGSQDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSVVPISYLCTYYATQKQNEFTCALGASPDGPVGSAGPTVRVSCKLPSVQLQRIIAGVDIVLLCFMNLIILVNLIHLFIFRKSNFIFDKLNKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEPDGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENSKTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDSGPSSAPPAASEKKHTRHFSLDVHPYILGTKKAKTEAVPPALPASRSQEGGFLSQTEECGLGLAAAPTKDAPLPEKEIPYPTEPALPGLPSGGSFHVCSPPAAPAAASLSPGSLGKADPLTILSRNATHPLLHISTLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVLFPKCH

Target ORF information:

RefSeq Version	XM_006521139.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus pannexin 2 (Panx2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521139.2

ORF Insert Sequence:

ATGCACCACC TCCTGGAGCA GTCGGCGGAC ATGGCGACCG CGCTGCTGGC GGGCGAGAAG 
CTGAGGGAGC TGATCCTGCC TGGCTCGCAG GACGACAAGG CGGGCGCGCT GGCCGCGCTG 
CTGCTGCAGC TCAAGCTGGA ACTGCCGTTC GACCGCGTGG TCACCATCGG CACCGTGCTG 
GTACCCATCC TGCTGGTCAC CCTGGTCTTC ACCAAGAACT TCGCAGAGGA ACCAATTTAC 
TGTTATACTC CGCACAACTT CACCCGTGAT CAGGCGCTGT ACGCCCGCGG CTACTGCTGG 
ACAGAGCTGC GGGACGCGCT GCCCGGCGTG GATGCCAGCC TCTGGCCATC GTTGTTTGAG 
CACAAGTTCC TGCCCTACGC GCTGCTGGCC TTTGCCGCCA TCATGTATGT GCCCGCGCTG 
GGCTGGGAGT TCCTCGCCTC CACGCGCCTC ACCTCGGAGC TCAACTTCCT TCTTCAGGAG 
ATCGACAACT GCTACCACCG AGCGGCCGAA GGTCGCGCAC CCAAGATTGA GAAGCAGATC 
CAGTCCAAGG GGCCCGGCAT CACGGAGCGC GAGAAGCGAG AGATCATTGA GAACGCCGAG 
AAGGAGAAGA GCCCGGAGCA GAATCTGTTT GAGAAGTACC TGGAACGCCG GGGCCGCAGC 
AACTTCCTGG CCAAGCTGTA CTTGGCACGG CACGTCCTGA TCCTGCTGCT CAGCGTGGTG 
CCCATCTCCT ACCTATGCAC ATACTACGCC ACCCAGAAGC AGAACGAGTT CACCTGTGCC 
CTGGGCGCCT CACCTGACGG GCCGGTGGGT AGCGCTGGGC CCACGGTGCG CGTCAGCTGT 
AAGCTACCGT CTGTGCAGCT GCAGCGGATC ATTGCAGGTG TGGACATCGT CTTGCTCTGC 
TTCATGAACC TCATCATCCT AGTCAACCTC ATCCACCTCT TCATCTTCCG CAAGAGCAAC 
TTCATCTTCG ACAAACTAAA CAAGGTGGGT ATCAAGACGC GCCGGCAGTG GCGCCGCTCG 
CAGTTCTGCG ACATCAACAT CCTGGCCATG TTCTGTAACG AGAACCGCGA CCACATCAAG 
TCGCTGAACC GGCTGGACTT CATCACCAAC GAGAGCGACC TCATGTACGA CAATGTGGTG 
CGGCAGCTTC TGGCTGCCTT GGCTCAGTCT AACCACGACA CCACGCCCAC TGTGCGGGAC 
TCTGGCATCC AGACCGTGGA CCCCAGCATC AACCCTGCGG AGCCTGATGG TTCTGCTGAG 
CCACCCGTGG TCAAGCGGCC CCGTAAGAAA ATGAAGTGGA TCCCCACCAG CAACCCGCTG 
CCACAGCCCT TCAAGGAGCA GCTGGCCATT ATGCGCGTGG AAAACAGCAA GACTGAGAAG 
CCCAAGCCCG TGCGCAGGAA GACAGCCACA GACACACTTA TTGCCCCGCT GCTGGACGCT 
GGTGCCCGTG CTGCCCACCA CTACAAGGGC AGTGGAGGTG ATTCAGGCCC CTCCTCTGCC 
CCGCCTGCTG CCTCTGAGAA AAAGCATACC CGCCACTTCT CCTTGGACGT GCATCCCTAT 
ATCCTAGGTA CCAAGAAGGC CAAGACTGAG GCGGTACCCC CTGCCCTACC AGCCTCCCGC 
AGCCAAGAAG GTGGCTTCCT GTCCCAGACA GAGGAATGTG GGCTGGGCCT AGCTGCAGCA 
CCCACCAAAG ATGCTCCACT CCCCGAGAAG GAAATCCCGT ACCCCACAGA GCCTGCCCTG 
CCAGGGCTCC CATCTGGGGG ATCATTCCAT GTCTGCTCAC CCCCCGCAGC CCCCGCCGCT 
GCTTCCCTGT CACCAGGCAG TCTGGGCAAG GCTGACCCTC TCACCATCCT GAGCCGGAAC 
GCCACTCACC CCCTGCTCCA CATCAGCACG CTGTATGAGG CCCGGGAAGA GGAGGAAGGA 
GGCCCCTGTG CCCCCTCAGA CATGGGCGAC CTCCTCAGCA TACCCCCGCC CCAGCAGATC 
CTCATCGCCA CCTTCGAGGA GCCGAGAACA GTTGTCCTGT TTCCCAAGTG CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pannexin-2-deficiency sensitizes pancreatic ?-cells to cytokine-induced apoptosis in?vitro and impairs glucose tolerance in?vivo.
Molecular and cellular endocrinology448108-121(2017 Jun)
Berchtold LA,Miani M,Diep TA,Madsen AN,Cigliola V,Colli M,Krivokapic JM,Pociot F,Eizirik DL,Meda P,Holst B,Billestrup N,St?rling J

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release.
The Journal of clinical investigation126(12)4527-4536(2016 Dec)
Wang S,Chennupati R,Kaur H,Iring A,Wettschureck N,Offermanns S

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
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Panx2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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