Mrgprx1 cDNA ORF clone, Mus musculus(house mouse)

Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.
Reddy VB, Lerner EA
The Journal of biological chemistry292(42)17399-17406(2017 10)

Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways.
Chang AY, Mann TS, McFawn PK, Han L, Dong X, Henry PJ
Respiratory research17(1)62(2016 May)

The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms.
Li Z, He SQ, Tseng PY, Xu Q, Tiwari V, Yang F, Shu B, Zhang T, Tang Z, Raja SN, Wang Y, Dong X, Guan Y
Neuroscience300393-403(2015 Aug)

Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.
Reddy VB, Sun S, Azimi E, Elmariah SB, Dong X, Lerner EA
Nature communications67864(2015 Jul)

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Kanai A, Takubo K, Suda T, Nakamura T, Wolff L, Honda H, Inaba T
Cancer cell24(3)305-17(2013 Sep)

Der p1 also induced the release of IL-6 from heterologous cells expressing MRGPRX1. In summary, activation of Mrgprs by the allergen Der p1 may contribute to inflammation.
Title: Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.

SLIGRL-amide inhibits influenza A virus infection independently of MRGPRC11 and independently of capsaicin-sensitive, neuropeptide-releasing sensory nerves.
Title: Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways.

Results suggest that activation of MrgC11 may inhibit high-voltage-activated calcium current in mouse dorsal root ganglion neurons through a voltage-independent mechanism that involves activation of the phospholipase C, but not Galphai or Galphas, pathway
Title: The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms.

Cathepsin S activates MrgprC11 and evokes receptor-dependent scratching in mice.
Title: Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.

analysis of the functional interactions between MRGPR-X1 and TRPV1
Title: Human sensory neuron-specific Mas-related G protein-coupled receptors-X1 sensitize and directly activate transient receptor potential cation channel V1 via distinct signaling pathways.