Bpifb4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bpifb4
Entrez Gene ID	381399
Full Name	BPI fold containing family B, member 4
Synonyms	Gm1006,Lplunc4
General protein information	Preferred Names BPI fold containing family B, member 4 Names BPI fold-containing family B member 4 LBP / BPI / CETP family, N-terminal domain containing protein Novel LBP/BPI/CETP family, N-terminal domain containing protein ligand-binding protein RY2G5 long palate, lung and nasal epithelium carcinoma-associated protein 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 H1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006499824.1	XP_006499887.1	BPI fold-containing family B member 4 isoform X1
NM_001034875.3	NP_001030047.2	BPI fold-containing family B member 4 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BPIFB4	XP_003586861.2
Mus musculus (house mouse)	Bpifb4	NP_001030047.2
Pan troglodytes (chimpanzee)	BPIFB4	XP_525303.2
Rattus norvegicus (Norway rat)	Bpifb4	NP_001102679.2
Homo sapiens (human)	BPIFB4	NP_872325.2
Canis lupus familiaris (dog)	BPIFB4	XP_534383.3
Gallus gallus (chicken)	BPIFB4	XP_425718.4

Gene Ontology
Bibliography

Related articles in PubMed

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.
Vecchione C, Villa F, Carrizzo A, Spinelli CC, Damato A, Ambrosio M, Ferrario A, Madonna M, Uccellatore A, Lupini S, Maciag A, Ryskalin L, Milanesi L, Frati G, Sciarretta S, Bellazzi R, Genovese S, Ceriello A, Auricchio A, Malovini A, Puca AA
Scientific reports7(1)9706(2017 Aug)

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism.
Spinelli CC, Carrizzo A, Ferrario A, Villa F, Damato A, Ambrosio M, Madonna M, Frati G, Fucile S, Sciaccaluga M, Capunzo M, Cal? G, Milanesi L, Maciag A, Puca AA, Vecchione C
Cardiovascular research113(7)795-804(2017 Jun)

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.
Villa F, Carrizzo A, Spinelli CC, Ferrario A, Malovini A, Maci?g A, Damato A, Auricchio A, Spinetti G, Sangalli E, Dang Z, Madonna M, Ambrosio M, Sitia L, Bigini P, Cal? G, Schreiber S, Perls T, Fucile S, Mulas F, Nebel A, Bellazzi R, Madeddu P, Vecchione C, Puca AA
Circulation research117(4)333-45(2015 Jul)

Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.
Bingle CD, Seal RL, Craven CJ
Biochemical Society transactions39(4)977-83(2011 Aug)

Phylogenetic and evolutionary analysis of the PLUNC gene family.
Bingle CD, LeClair EE, Havard S, Bingle L, Gillingham P, Craven CJ
Protein science : a publication of the Protein Society13(2)422-30(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Bpifb4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bpifb4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16163	NM_001034875.3 Latest version!	Mus musculus BPI fold containing family B, member 4 (Bpifb4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu16163	XM_006499824.1 Latest version!	Mus musculus BPI fold containing family B, member 4 (Bpifb4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bpifb4 ( NM_001034875.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001030047.2 Mus musculus BPI fold containing family B, member 4 (Bpifb4), mRNA.

Price & Availability↑

CloneID	OMu16163
Clone ID Related Accession (Same CDS sequence)	XM_006499824.1 , NM_001034875.3
Accession Version	NM_001034875.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1854bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	BPI fold-containing family B member 4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX470156.7. On Feb 12, 2009 this sequence version replaced NM_001034875.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA 
GACACAACCA CAGTCCTCAG GGTTACAAAA GATGTGCTGG GCAATGCCAT CTCAGGCACA 
ATTCAGAAGA GTGACGCCTT CCGCTCCGCC CTGAGGGAGG TGCCCGTGGG TGTCGGTGGT 
GTCCCGTACA ACGACTTCCA TGTCCGAGAG CCTCCCCCCA AATACACCAA TGGCAGACAG 
CTTGGTGGCA ATTACAAATA TGGTCACATT AAGGCGAACG ACAATAGAGC TCAGCTGGGG 
GGCAAGTACC GCTATGGGGA GATCCTGGAC TCCGATGGGA GCCTCAGGGA CCTACGGCAT 
GAAGACTACC GTCCTCCAGA CAGTGCCTAC CACCGCGGCT CTGGGCGGTA CAGATCCGCC 
GCAGACTCAT CCTCGGTGGG CAGGCTCTAC CGGCGCGAAC TGAGGCCTGG AGAGATCCCA 
GCTGGTGTGG CCACTGGGGC CCTGGGCCCC GGAGGTCTGC TGGGCACAGG GGGCATGCTG 
GCAAATGAAG GCATTCTGGC AGGCCAAGGG GGCTTGCTTG GTGGAGGTGG TCTTCTTGGA 
GATGGAGGAC TTCTTGGAGG AGGAGGTGTG CTCGGTGTGC TGGGTGAAGG AGGCATCCTA 
AGCACCGTAC AAGGCATCAC TGGGTTGCGC ATCGTGGAAC TTACCCTTCC CCGGGTGTCC 
GTGAGACTCC TGCCCGGTGT GGGTGTCTAC CTGAGCTTGT ACACCCGTGT GGCCATCAAC 
GGAAGGAGCC TCATCGGCTT CCTGGATATT GCAGTGGAGG TAAACATCAC GGCCAAAGTT 
CGGCTGACCA TGGACCGCAC AGGCTACCCA CGGTTGGTCA TTGAGCGCTG TGACACCCTC 
CTGGGAGGTA TCAAAGTCAA GCTGCTTCGA GGGCTTCTCC CCAACCTGGT GGACAACTTA 
GTGAACCGAG TGCTGGCCAA TGTACTCCCT GACCTGCTCT GCCCCATTGT GGATGTGGTA 
TTGGGTCTTG TCAATGACCA GCTGGGTCTC GTGGACTCTT TGGTGCCTCT GGGAATACTT 
GGGAGTGTGC AATACACTTT CTCCAGCCTT CCACTGGTGA CTGGGGAATT CCTTGAGTTG 
GACCTTAATA CTCTAGTTGG GGAGGCAGGA GGTGACCTCA TTGACTACCC CCTGGGGCGG 
CCAGCTATAT TGCCCAGGCC ACAGATGCCA GAACTACCCC CCATGGGCGA CAACACCAAC 
TCCCAGCTGG CCATCTCAGC CAATTTCCTG AGCTCGGTGC TGACCATGCT GCAGAAGCAA 
GGTGCAATGG ACATTGACAT CACTGATGGC ATGTTTGAAG ATCTCCCTCC ACTTACCACT 
TCCACACTGG GGGCCTTGAT TCCCAAGGTG TTCCAGCAAT ACCCGGAATC CCGCCCACTC 
ACCATCAGGA TCCAGGTGCC CAACCCTCCA ACTGTGACAC TGCAGAAAGA CAAGGCGCTG 
GTGAAGGTGT TCGCCACCTC TGAAGTTGTG GTCTCCCAGC CCAACGATGT AGAGACCACT 
ATCTGCCTCA TCGATGTGGA CACAGACCTC TTGGCTTCAT TTTCTGTGGA AGGAGATAAG 
CTCATGATCG ACGCCAAGCT GGATAAGACC AGCCTCAACC TCAGAACCTC AAACGTGGGC 
AACTTTGATG TGTTCATCTT GGAAATGTTG GTTGAGAAGA TCTTTGACCT AGCGTTTATG 
CCTGCAATGA ATGCTATACT GGGTTCTGGA GTCCCCCTGC CCAAAATCCT CAACATTGAC 
TTCAGCAACG CAGACATTGA TGTGTTGGAG GACCTTCTGG TGCTGAGCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030047.2
CDS	16..1869
Translation	MWTAWCVAALSVAAVCGIRQDTTTVLRVTKDVLGNAISGTIQKSDAFRSALREVPVGVGGVPYNDFHVREPPPKYTNGRQLGGNYKYGHIKANDNRAQLGGKYRYGEILDSDGSLRDLRHEDYRPPDSAYHRGSGRYRSAADSSSVGRLYRRELRPGEIPAGVATGALGPGGLLGTGGMLANEGILAGQGGLLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYLSLYTRVAINGRSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLGGIKVKLLRGLLPNLVDNLVNRVLANVLPDLLCPIVDVVLGLVNDQLGLVDSLVPLGILGSVQYTFSSLPLVTGEFLELDLNTLVGEAGGDLIDYPLGRPAILPRPQMPELPPMGDNTNSQLAISANFLSSVLTMLQKQGAMDIDITDGMFEDLPPLTTSTLGALIPKVFQQYPESRPLTIRIQVPNPPTVTLQKDKALVKVFATSEVVVSQPNDVETTICLIDVDTDLLASFSVEGDKLMIDAKLDKTSLNLRTSNVGNFDVFILEMLVEKIFDLAFMPAMNAILGSGVPLPKILNIDFSNADIDVLEDLLVLST

Target ORF information:

RefSeq Version	NM_001034875.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus BPI fold containing family B, member 4 (Bpifb4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034875.3

ORF Insert Sequence:

ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA 
GACACAACCA CAGTCCTCAG GGTTACAAAA GATGTGCTGG GCAATGCCAT CTCAGGCACA 
ATTCAGAAGA GTGACGCCTT CCGCTCCGCC CTGAGGGAGG TGCCCGTGGG TGTCGGTGGT 
GTCCCGTACA ACGACTTCCA TGTCCGAGAG CCTCCCCCCA AATACACCAA TGGCAGACAG 
CTTGGTGGCA ATTACAAATA TGGTCACATT AAGGCGAACG ACAATAGAGC TCAGCTGGGG 
GGCAAGTACC GCTATGGGGA GATCCTGGAC TCCGATGGGA GCCTCAGGGA CCTACGGCAT 
GAAGACTACC GTCCTCCAGA CAGTGCCTAC CACCGCGGCT CTGGGCGGTA CAGATCCGCC 
GCAGACTCAT CCTCGGTGGG CAGGCTCTAC CGGCGCGAAC TGAGGCCTGG AGAGATCCCA 
GCTGGTGTGG CCACTGGGGC CCTGGGCCCC GGAGGTCTGC TGGGCACAGG GGGCATGCTG 
GCAAATGAAG GCATTCTGGC AGGCCAAGGG GGCTTGCTTG GTGGAGGTGG TCTTCTTGGA 
GATGGAGGAC TTCTTGGAGG AGGAGGTGTG CTCGGTGTGC TGGGTGAAGG AGGCATCCTA 
AGCACCGTAC AAGGCATCAC TGGGTTGCGC ATCGTGGAAC TTACCCTTCC CCGGGTGTCC 
GTGAGACTCC TGCCCGGTGT GGGTGTCTAC CTGAGCTTGT ACACCCGTGT GGCCATCAAC 
GGAAGGAGCC TCATCGGCTT CCTGGATATT GCAGTGGAGG TAAACATCAC GGCCAAAGTT 
CGGCTGACCA TGGACCGCAC AGGCTACCCA CGGTTGGTCA TTGAGCGCTG TGACACCCTC 
CTGGGAGGTA TCAAAGTCAA GCTGCTTCGA GGGCTTCTCC CCAACCTGGT GGACAACTTA 
GTGAACCGAG TGCTGGCCAA TGTACTCCCT GACCTGCTCT GCCCCATTGT GGATGTGGTA 
TTGGGTCTTG TCAATGACCA GCTGGGTCTC GTGGACTCTT TGGTGCCTCT GGGAATACTT 
GGGAGTGTGC AATACACTTT CTCCAGCCTT CCACTGGTGA CTGGGGAATT CCTTGAGTTG 
GACCTTAATA CTCTAGTTGG GGAGGCAGGA GGTGACCTCA TTGACTACCC CCTGGGGCGG 
CCAGCTATAT TGCCCAGGCC ACAGATGCCA GAACTACCCC CCATGGGCGA CAACACCAAC 
TCCCAGCTGG CCATCTCAGC CAATTTCCTG AGCTCGGTGC TGACCATGCT GCAGAAGCAA 
GGTGCAATGG ACATTGACAT CACTGATGGC ATGTTTGAAG ATCTCCCTCC ACTTACCACT 
TCCACACTGG GGGCCTTGAT TCCCAAGGTG TTCCAGCAAT ACCCGGAATC CCGCCCACTC 
ACCATCAGGA TCCAGGTGCC CAACCCTCCA ACTGTGACAC TGCAGAAAGA CAAGGCGCTG 
GTGAAGGTGT TCGCCACCTC TGAAGTTGTG GTCTCCCAGC CCAACGATGT AGAGACCACT 
ATCTGCCTCA TCGATGTGGA CACAGACCTC TTGGCTTCAT TTTCTGTGGA AGGAGATAAG 
CTCATGATCG ACGCCAAGCT GGATAAGACC AGCCTCAACC TCAGAACCTC AAACGTGGGC 
AACTTTGATG TGTTCATCTT GGAAATGTTG GTTGAGAAGA TCTTTGACCT AGCGTTTATG 
CCTGCAATGA ATGCTATACT GGGTTCTGGA GTCCCCCTGC CCAAAATCCT CAACATTGAC 
TTCAGCAACG CAGACATTGA TGTGTTGGAG GACCTTCTGG TGCTGAGCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bpifb4 ( XM_006499824.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499887.1 Mus musculus BPI fold containing family B, member 4 (Bpifb4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu16163
Clone ID Related Accession (Same CDS sequence)	XM_006499824.1 , NM_001034875.3
Accession Version	XM_006499824.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1854bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	BPI fold-containing family B member 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA 
GACACAACCA CAGTCCTCAG GGTTACAAAA GATGTGCTGG GCAATGCCAT CTCAGGCACA 
ATTCAGAAGA GTGACGCCTT CCGCTCCGCC CTGAGGGAGG TGCCCGTGGG TGTCGGTGGT 
GTCCCGTACA ACGACTTCCA TGTCCGAGAG CCTCCCCCCA AATACACCAA TGGCAGACAG 
CTTGGTGGCA ATTACAAATA TGGTCACATT AAGGCGAACG ACAATAGAGC TCAGCTGGGG 
GGCAAGTACC GCTATGGGGA GATCCTGGAC TCCGATGGGA GCCTCAGGGA CCTACGGCAT 
GAAGACTACC GTCCTCCAGA CAGTGCCTAC CACCGCGGCT CTGGGCGGTA CAGATCCGCC 
GCAGACTCAT CCTCGGTGGG CAGGCTCTAC CGGCGCGAAC TGAGGCCTGG AGAGATCCCA 
GCTGGTGTGG CCACTGGGGC CCTGGGCCCC GGAGGTCTGC TGGGCACAGG GGGCATGCTG 
GCAAATGAAG GCATTCTGGC AGGCCAAGGG GGCTTGCTTG GTGGAGGTGG TCTTCTTGGA 
GATGGAGGAC TTCTTGGAGG AGGAGGTGTG CTCGGTGTGC TGGGTGAAGG AGGCATCCTA 
AGCACCGTAC AAGGCATCAC TGGGTTGCGC ATCGTGGAAC TTACCCTTCC CCGGGTGTCC 
GTGAGACTCC TGCCCGGTGT GGGTGTCTAC CTGAGCTTGT ACACCCGTGT GGCCATCAAC 
GGAAGGAGCC TCATCGGCTT CCTGGATATT GCAGTGGAGG TAAACATCAC GGCCAAAGTT 
CGGCTGACCA TGGACCGCAC AGGCTACCCA CGGTTGGTCA TTGAGCGCTG TGACACCCTC 
CTGGGAGGTA TCAAAGTCAA GCTGCTTCGA GGGCTTCTCC CCAACCTGGT GGACAACTTA 
GTGAACCGAG TGCTGGCCAA TGTACTCCCT GACCTGCTCT GCCCCATTGT GGATGTGGTA 
TTGGGTCTTG TCAATGACCA GCTGGGTCTC GTGGACTCTT TGGTGCCTCT GGGAATACTT 
GGGAGTGTGC AATACACTTT CTCCAGCCTT CCACTGGTGA CTGGGGAATT CCTTGAGTTG 
GACCTTAATA CTCTAGTTGG GGAGGCAGGA GGTGACCTCA TTGACTACCC CCTGGGGCGG 
CCAGCTATAT TGCCCAGGCC ACAGATGCCA GAACTACCCC CCATGGGCGA CAACACCAAC 
TCCCAGCTGG CCATCTCAGC CAATTTCCTG AGCTCGGTGC TGACCATGCT GCAGAAGCAA 
GGTGCAATGG ACATTGACAT CACTGATGGC ATGTTTGAAG ATCTCCCTCC ACTTACCACT 
TCCACACTGG GGGCCTTGAT TCCCAAGGTG TTCCAGCAAT ACCCGGAATC CCGCCCACTC 
ACCATCAGGA TCCAGGTGCC CAACCCTCCA ACTGTGACAC TGCAGAAAGA CAAGGCGCTG 
GTGAAGGTGT TCGCCACCTC TGAAGTTGTG GTCTCCCAGC CCAACGATGT AGAGACCACT 
ATCTGCCTCA TCGATGTGGA CACAGACCTC TTGGCTTCAT TTTCTGTGGA AGGAGATAAG 
CTCATGATCG ACGCCAAGCT GGATAAGACC AGCCTCAACC TCAGAACCTC AAACGTGGGC 
AACTTTGATG TGTTCATCTT GGAAATGTTG GTTGAGAAGA TCTTTGACCT AGCGTTTATG 
CCTGCAATGA ATGCTATACT GGGTTCTGGA GTCCCCCTGC CCAAAATCCT CAACATTGAC 
TTCAGCAACG CAGACATTGA TGTGTTGGAG GACCTTCTGG TGCTGAGCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499887.1
CDS	76..1929
Translation	MWTAWCVAALSVAAVCGIRQDTTTVLRVTKDVLGNAISGTIQKSDAFRSALREVPVGVGGVPYNDFHVREPPPKYTNGRQLGGNYKYGHIKANDNRAQLGGKYRYGEILDSDGSLRDLRHEDYRPPDSAYHRGSGRYRSAADSSSVGRLYRRELRPGEIPAGVATGALGPGGLLGTGGMLANEGILAGQGGLLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYLSLYTRVAINGRSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLGGIKVKLLRGLLPNLVDNLVNRVLANVLPDLLCPIVDVVLGLVNDQLGLVDSLVPLGILGSVQYTFSSLPLVTGEFLELDLNTLVGEAGGDLIDYPLGRPAILPRPQMPELPPMGDNTNSQLAISANFLSSVLTMLQKQGAMDIDITDGMFEDLPPLTTSTLGALIPKVFQQYPESRPLTIRIQVPNPPTVTLQKDKALVKVFATSEVVVSQPNDVETTICLIDVDTDLLASFSVEGDKLMIDAKLDKTSLNLRTSNVGNFDVFILEMLVEKIFDLAFMPAMNAILGSGVPLPKILNIDFSNADIDVLEDLLVLST

Target ORF information:

RefSeq Version	XM_006499824.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus BPI fold containing family B, member 4 (Bpifb4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499824.1

ORF Insert Sequence:

ATGTGGACTG CGTGGTGTGT GGCTGCTCTG TCAGTGGCAG CTGTGTGTGG TATCCGCCAA 
GACACAACCA CAGTCCTCAG GGTTACAAAA GATGTGCTGG GCAATGCCAT CTCAGGCACA 
ATTCAGAAGA GTGACGCCTT CCGCTCCGCC CTGAGGGAGG TGCCCGTGGG TGTCGGTGGT 
GTCCCGTACA ACGACTTCCA TGTCCGAGAG CCTCCCCCCA AATACACCAA TGGCAGACAG 
CTTGGTGGCA ATTACAAATA TGGTCACATT AAGGCGAACG ACAATAGAGC TCAGCTGGGG 
GGCAAGTACC GCTATGGGGA GATCCTGGAC TCCGATGGGA GCCTCAGGGA CCTACGGCAT 
GAAGACTACC GTCCTCCAGA CAGTGCCTAC CACCGCGGCT CTGGGCGGTA CAGATCCGCC 
GCAGACTCAT CCTCGGTGGG CAGGCTCTAC CGGCGCGAAC TGAGGCCTGG AGAGATCCCA 
GCTGGTGTGG CCACTGGGGC CCTGGGCCCC GGAGGTCTGC TGGGCACAGG GGGCATGCTG 
GCAAATGAAG GCATTCTGGC AGGCCAAGGG GGCTTGCTTG GTGGAGGTGG TCTTCTTGGA 
GATGGAGGAC TTCTTGGAGG AGGAGGTGTG CTCGGTGTGC TGGGTGAAGG AGGCATCCTA 
AGCACCGTAC AAGGCATCAC TGGGTTGCGC ATCGTGGAAC TTACCCTTCC CCGGGTGTCC 
GTGAGACTCC TGCCCGGTGT GGGTGTCTAC CTGAGCTTGT ACACCCGTGT GGCCATCAAC 
GGAAGGAGCC TCATCGGCTT CCTGGATATT GCAGTGGAGG TAAACATCAC GGCCAAAGTT 
CGGCTGACCA TGGACCGCAC AGGCTACCCA CGGTTGGTCA TTGAGCGCTG TGACACCCTC 
CTGGGAGGTA TCAAAGTCAA GCTGCTTCGA GGGCTTCTCC CCAACCTGGT GGACAACTTA 
GTGAACCGAG TGCTGGCCAA TGTACTCCCT GACCTGCTCT GCCCCATTGT GGATGTGGTA 
TTGGGTCTTG TCAATGACCA GCTGGGTCTC GTGGACTCTT TGGTGCCTCT GGGAATACTT 
GGGAGTGTGC AATACACTTT CTCCAGCCTT CCACTGGTGA CTGGGGAATT CCTTGAGTTG 
GACCTTAATA CTCTAGTTGG GGAGGCAGGA GGTGACCTCA TTGACTACCC CCTGGGGCGG 
CCAGCTATAT TGCCCAGGCC ACAGATGCCA GAACTACCCC CCATGGGCGA CAACACCAAC 
TCCCAGCTGG CCATCTCAGC CAATTTCCTG AGCTCGGTGC TGACCATGCT GCAGAAGCAA 
GGTGCAATGG ACATTGACAT CACTGATGGC ATGTTTGAAG ATCTCCCTCC ACTTACCACT 
TCCACACTGG GGGCCTTGAT TCCCAAGGTG TTCCAGCAAT ACCCGGAATC CCGCCCACTC 
ACCATCAGGA TCCAGGTGCC CAACCCTCCA ACTGTGACAC TGCAGAAAGA CAAGGCGCTG 
GTGAAGGTGT TCGCCACCTC TGAAGTTGTG GTCTCCCAGC CCAACGATGT AGAGACCACT 
ATCTGCCTCA TCGATGTGGA CACAGACCTC TTGGCTTCAT TTTCTGTGGA AGGAGATAAG 
CTCATGATCG ACGCCAAGCT GGATAAGACC AGCCTCAACC TCAGAACCTC AAACGTGGGC 
AACTTTGATG TGTTCATCTT GGAAATGTTG GTTGAGAAGA TCTTTGACCT AGCGTTTATG 
CCTGCAATGA ATGCTATACT GGGTTCTGGA GTCCCCCTGC CCAAAATCCT CAACATTGAC 
TTCAGCAACG CAGACATTGA TGTGTTGGAG GACCTTCTGG TGCTGAGCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.
Scientific reports7(1)9706(2017 Aug)
Vecchione C,Villa F,Carrizzo A,Spinelli CC,Damato A,Ambrosio M,Ferrario A,Madonna M,Uccellatore A,Lupini S,Maciag A,Ryskalin L,Milanesi L,Frati G,Sciarretta S,Bellazzi R,Genovese S,Ceriello A,Auricchio A,Malovini A,Puca AA

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism.
Cardiovascular research113(7)795-804(2017 Jun)
Spinelli CC,Carrizzo A,Ferrario A,Villa F,Damato A,Ambrosio M,Madonna M,Frati G,Fucile S,Sciaccaluga M,Capunzo M,Cal? G,Milanesi L,Maciag A,Puca AA,Vecchione C

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.
Circulation research117(4)333-45(2015 Jul)
Villa F,Carrizzo A,Spinelli CC,Ferrario A,Malovini A,Maci?g A,Damato A,Auricchio A,Spinetti G,Sangalli E,Dang Z,Madonna M,Ambrosio M,Sitia L,Bigini P,Cal? G,Schreiber S,Perls T,Fucile S,Mulas F,Nebel A,Bellazzi R,Madeddu P,Vecchione C,Puca AA

Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.
Biochemical Society transactions39(4)977-83(2011 Aug)
Bingle CD,Seal RL,Craven CJ

Phylogenetic and evolutionary analysis of the PLUNC gene family.
Protein science : a publication of the Protein Society13(2)422-30(2004 Feb)
Bingle CD,LeClair EE,Havard S,Bingle L,Gillingham P,Craven CJ

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Bpifb4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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