Scarf1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scarf1
Entrez Gene ID	380713
Full Name	scavenger receptor class F, member 1
Synonyms	AA986099,SREC,SREC-I,mKIAA0149
General protein information	Preferred Names scavenger receptor class F, member 1 Names scavenger receptor class F member 1 acetyl LDL receptor scavenger receptor expressed by endothelial cells 1 protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B5

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004157.2	NP_001004157.2	scavenger receptor class F member 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SCARF1	XP_003954499.1
Bos taurus (cattle)	SCARF1	XP_002695728.3
Mus musculus (house mouse)	Scarf1	NP_001004157.2
Rattus norvegicus (Norway rat)	Scarf1	NP_001100492.1
	SCARF1	XP_001117324.1
Danio rerio (zebrafish)	LOC100005273	XP_001344375.3
Homo sapiens (human)	SCARF1	NP_003684.2
Canis lupus familiaris (dog)	SCARF1	XP_853984.2
Gallus gallus (chicken)	SCARF1	XP_004946587.1
Xenopus tropicalis (tropical clawed frog)	scarf1	XP_002936099.2

Gene Ontology
Bibliography

Related articles in PubMed

Scavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 264.7 cells upon LPS activation.
Murshid A, Gong J, Prince T, Borges TJ, Calderwood SK
PloS one10(4)e0122529(2015)

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.
Ramirez-Ortiz ZG, Pendergraft WF 3rd, Prasad A, Byrne MH, Iram T, Blanchette CJ, Luster AD, Hacohen N, El Khoury J, Means TK
Nature immunology14(9)917-26(2013 Sep)

Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.
Murshid A, Gong J, Calderwood SK
Journal of immunology (Baltimore, Md. : 1950)185(5)2903-17(2010 Sep)

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36.
Means TK, Mylonakis E, Tampakakis E, Colvin RA, Seung E, Puckett L, Tai MF, Stewart CR, Pukkila-Worley R, Hickman SE, Moore KJ, Calderwood SB, Hacohen N, Luster AD, El Khoury J
The Journal of experimental medicine206(3)637-53(2009 Mar)

Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene.
Hasegawa H, Abbott S, Han BX, Qi Y, Wang F
The Journal of neuroscience : the official journal of the Society for Neuroscience27(52)14404-14(2007 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SREC-I became associated with TLR4 on binding bacterial lipopolysaccharides in RAW 264.7.
Title: Scavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 264.7 cells upon LPS activation.

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.
Title: The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.

SREC-I mediated internalization of Hsp90-ovalbumin polypeptide complexes through an endocytic pathway known as the glycosylphosphatidylinositol-anchored protein-enriched early endosomal compartment to recycling endosomes.
Title: Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.

CED-1/SCARF1 and C03F11.3/CD36 are beta-glucan binding receptors and define an evolutionarily conserved pathway for the innate sensing of fungal pathogens.
Title: Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36.

Our system may be useful for the elucidation of the mechanism of morphological maturation of neuronal cells such as dorsal root ganglion neurons that express SREC-I during early development.
Title: Scavenger receptor expressed by endothelial cells (SREC)-I interacts with protein phosphatase 1alpha in L cells to induce neurite-like outgrowth.

The following Scarf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scarf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15052	NM_001004157.2 Latest version!	Mus musculus scavenger receptor class F, member 1 (Scarf1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$482.30 $689.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scarf1 ( NM_001004157.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001004157.2 Mus musculus scavenger receptor class F, member 1 (Scarf1), mRNA.

Price & Availability↑

CloneID	OMu15052
Clone ID Related Accession (Same CDS sequence)	NM_001004157.2
Accession Version	NM_001004157.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2463bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Mus musculus(house mouse)
Product	scavenger receptor class F member 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC080288.1, AK220215.1 and AK133477.1. On Feb 14, 2006 this sequence version replaced NM_001004157.1. ##Evidence-Data-START## Transcript exon combination :: AK133477.1, AK220215.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCTGGCCG CCATGGGACT AGAGCTGGTG TTCTCACTGT TGCTGCTCTG GACTCAGGGG 
ACCCAGGGAT CCACGCTAGA CCCTGCTGGT CAGCACGTCT GTAAAGGCAG CAGCCCCTCT 
GAGCTCCAGT GTTGTCCCGG CTGGAGGCAG AAAGATCAAG AATGCACCAT CCCCATCTGT 
GAGGGGCCTG ATGCCTGCAG GAAAGAAGAG GTGTGCGTGA AGCCGGGCCT CTGTCGGTGT 
AAACCTGGAT TCTTCGGAGC CCAGTGCAGC TCCCGCTGTC CAGGACAGTA CTGGGGCCAC 
GACTGTCGTG AGACCTGCCC CTGTCATCCA CGTGGCCAGT GCGAACCGGC CACGGGTGAT 
TGCCAATGCC AGCCTAACTA CTGGGGCAGG CTCTGTGAGT TCCCCTGCAC CTGCGGCCCC 
CACGGACAGT GCGACCCAAA GACAGGCTTG TGCCACTGTG ACCCTGGCTG GTGGTCACCC 
ACGTGTCGTC GCCCATGCCA GTGCAACCCA GCCTCACGCT GTGACCAGGC CACTGGAACC 
TGTGTATGCC CGCCGGGCTG GTGGGGCCGC CGCTGCAGCT TCAGTTGCAA CTGCCACACC 
TCGCCCTGCA TGCAGGACTC CGGCCGCTGC GTCTGCCTGC CGGGCTGGTG GGGTCCGGAG 
TGCAGTCGTA AGTGCCAGTG TGTGCGAGGC CAATGCAGCG TTACTTCTGG CCACTGTTCC 
TGCCCTCCTG GCTTCCATGG AATCCGCTGT GAGCTGCCTT GCAACCCTGG CCACTATGGG 
GCACAGTGCA AAGAAAGCTG TGGCCACTGT GAGCTGAATG CCACATGCTC TCCAGTCACC 
GGCAACTGTG AGTCCTGCAA GCCAGGCTGG AACGGTACTC AGTGCAAGCA GCCATGTCCT 
GCAGGCACCT TTGGTGAGAG GTGCACTGGG CAGTGCCCCC GCTGCCGGCT TGGGGAGCCC 
TGTCAAGCGG AAACTGGGCA CTGCCAGCAC TGCGACCCCG GTTGGCTGGG GCACAGGTGT 
GAGAACCCTT GTCCCCTTGG CACCTTTGGG AAGGGCTGCA GCTCAACCTG CCCTGCCTGT 
GCTCAGGGGA CTTGCGATGC CGTGACTGGG GAATGTGTCT GCAGTGCTGG CTACTGGGGG 
ACCAGCTGCA ACAGTTCCTG CCCAGCTGGC TTCCACGGAA ACAACTGCTC TATGCCCTGC 
CAATGCCCAG AGGGGCTCTG CCACCCTGTG TCTGGGACCT GCCAGCTGGG CCGTCATGGT 
AAGAACGCCC TCATTGTGGG CATCCTGGTA CCTCTGCTGC TGCTCCTCAT GGGCATCGTC 
TGCTGTGCCT ACTGCTGCTC AGGAACCCGA CTGGACCCCA AGGACAGGCC TGAGAGAAAT 
GGGGCTGCCT TTTTCAGAAT GAAGCAGCAG GTATGGGGGG CCCTCACCAA CTTGGGCTCG 
GCACTGCCCT GTGGCTCCCT CAGTAACTAC AAGCTACCCT GGGTGACAGT TTCTCATCAC 
GATCCAGAGG TCCCCTTCAA CCATAGCTTC ATCGAGCCCC CCTCTGCCGG CTGGGCCTCT 
GACGACTCCT TCTCTTCTGA TCCTGACTCT GGAGAAGAGG ACGAAGCTCA TGCCTACTTC 
GTGCCGCCTC GAGAAGAGAT GGTCCCTATG GCCCAAGAAG AGTCACCAGA AGCCAGCCTT 
CCTGGAGGCT CCTTCCCTCC CCCTGAGGAT GCCTCCACAC CATTCCCCAT TCCACGTACC 
TCCAGCCTGG CTAGGGCCAA GAGGCCATCC GTCTCCTTTG CTGAAGGCAC GAAGTTTGCA 
CCACAGAATG GCCGAAGCTC TGGGGATCTC TCCAGCCCCA TACGAAAACC CAAGAGACTC 
TCCAGAGGTG CTCAACCCCG TCCTGAAGGG CAGGAGGCGG AGGAGTCTAC AGGCCCAGAG 
CAAGTGAACA CAGAGGAGGA TGCTCCTACG GCCACAAGCT CTGGAGATCC TGCCACTAGT 
CACGGCCAAC TTCCACCTGG TAGCCAGATG GTAGCTGAGT GTGCGGAGAC CACTGATGGA 
GGCATCCAGG AGAGCTCAGG ATCTGTGGCC ACTATCTATA TGCTGGCAGG GACACCTCAG 
AAACCTGAGG GTCCTGTCTG GTCTGTCTTT CGTCGTTTGG GAAACTACCA GAAAGATCAG 
ATGGATCCCA AAGTAAAGAG TGCTATCCCT AAGCCTCTGC GCCGATCTCT GGGTCGGAAC 
CAGGCCAGCG CTGGCTCAGC TCCAGGTGCT GTGCTCTCCC AGGCCATGGA GTCCACCGCA 
GTTAGACCAG AGGAAACACC CAGAGGTCTG GGAGATGGCA TTGAGAGCTC AGGGACTGTC 
CAGGAGCCAG ACGCTGGAGG CAGTTCCCTG GAACAGGATT CCCAGAAGCA GGCGGAAGAG 
AAGGAGCAAG AGGAGCCCCT GTATGAGAAT GTTGTGCCCA TGTCCGTGCC GCCACAGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004157.2
CDS	38..2500
Translation	MLAAMGLELVFSLLLLWTQGTQGSTLDPAGQHVCKGSSPSELQCCPGWRQKDQECTIPICEGPDACRKEEVCVKPGLCRCKPGFFGAQCSSRCPGQYWGHDCRETCPCHPRGQCEPATGDCQCQPNYWGRLCEFPCTCGPHGQCDPKTGLCHCDPGWWSPTCRRPCQCNPASRCDQATGTCVCPPGWWGRRCSFSCNCHTSPCMQDSGRCVCLPGWWGPECSRKCQCVRGQCSVTSGHCSCPPGFHGIRCELPCNPGHYGAQCKESCGHCELNATCSPVTGNCESCKPGWNGTQCKQPCPAGTFGERCTGQCPRCRLGEPCQAETGHCQHCDPGWLGHRCENPCPLGTFGKGCSSTCPACAQGTCDAVTGECVCSAGYWGTSCNSSCPAGFHGNNCSMPCQCPEGLCHPVSGTCQLGRHGKNALIVGILVPLLLLLMGIVCCAYCCSGTRLDPKDRPERNGAAFFRMKQQVWGALTNLGSALPCGSLSNYKLPWVTVSHHDPEVPFNHSFIEPPSAGWASDDSFSSDPDSGEEDEAHAYFVPPREEMVPMAQEESPEASLPGGSFPPPEDASTPFPIPRTSSLARAKRPSVSFAEGTKFAPQNGRSSGDLSSPIRKPKRLSRGAQPRPEGQEAEESTGPEQVNTEEDAPTATSSGDPATSHGQLPPGSQMVAECAETTDGGIQESSGSVATIYMLAGTPQKPEGPVWSVFRRLGNYQKDQMDPKVKSAIPKPLRRSLGRNQASAGSAPGAVLSQAMESTAVRPEETPRGLGDGIESSGTVQEPDAGGSSLEQDSQKQAEEKEQEEPLYENVVPMSVPPQH

Target ORF information:

RefSeq Version	NM_001004157.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus scavenger receptor class F, member 1 (Scarf1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004157.2

ORF Insert Sequence:

ATGCTGGCCG CCATGGGACT AGAGCTGGTG TTCTCACTGT TGCTGCTCTG GACTCAGGGG 
ACCCAGGGAT CCACGCTAGA CCCTGCTGGT CAGCACGTCT GTAAAGGCAG CAGCCCCTCT 
GAGCTCCAGT GTTGTCCCGG CTGGAGGCAG AAAGATCAAG AATGCACCAT CCCCATCTGT 
GAGGGGCCTG ATGCCTGCAG GAAAGAAGAG GTGTGCGTGA AGCCGGGCCT CTGTCGGTGT 
AAACCTGGAT TCTTCGGAGC CCAGTGCAGC TCCCGCTGTC CAGGACAGTA CTGGGGCCAC 
GACTGTCGTG AGACCTGCCC CTGTCATCCA CGTGGCCAGT GCGAACCGGC CACGGGTGAT 
TGCCAATGCC AGCCTAACTA CTGGGGCAGG CTCTGTGAGT TCCCCTGCAC CTGCGGCCCC 
CACGGACAGT GCGACCCAAA GACAGGCTTG TGCCACTGTG ACCCTGGCTG GTGGTCACCC 
ACGTGTCGTC GCCCATGCCA GTGCAACCCA GCCTCACGCT GTGACCAGGC CACTGGAACC 
TGTGTATGCC CGCCGGGCTG GTGGGGCCGC CGCTGCAGCT TCAGTTGCAA CTGCCACACC 
TCGCCCTGCA TGCAGGACTC CGGCCGCTGC GTCTGCCTGC CGGGCTGGTG GGGTCCGGAG 
TGCAGTCGTA AGTGCCAGTG TGTGCGAGGC CAATGCAGCG TTACTTCTGG CCACTGTTCC 
TGCCCTCCTG GCTTCCATGG AATCCGCTGT GAGCTGCCTT GCAACCCTGG CCACTATGGG 
GCACAGTGCA AAGAAAGCTG TGGCCACTGT GAGCTGAATG CCACATGCTC TCCAGTCACC 
GGCAACTGTG AGTCCTGCAA GCCAGGCTGG AACGGTACTC AGTGCAAGCA GCCATGTCCT 
GCAGGCACCT TTGGTGAGAG GTGCACTGGG CAGTGCCCCC GCTGCCGGCT TGGGGAGCCC 
TGTCAAGCGG AAACTGGGCA CTGCCAGCAC TGCGACCCCG GTTGGCTGGG GCACAGGTGT 
GAGAACCCTT GTCCCCTTGG CACCTTTGGG AAGGGCTGCA GCTCAACCTG CCCTGCCTGT 
GCTCAGGGGA CTTGCGATGC CGTGACTGGG GAATGTGTCT GCAGTGCTGG CTACTGGGGG 
ACCAGCTGCA ACAGTTCCTG CCCAGCTGGC TTCCACGGAA ACAACTGCTC TATGCCCTGC 
CAATGCCCAG AGGGGCTCTG CCACCCTGTG TCTGGGACCT GCCAGCTGGG CCGTCATGGT 
AAGAACGCCC TCATTGTGGG CATCCTGGTA CCTCTGCTGC TGCTCCTCAT GGGCATCGTC 
TGCTGTGCCT ACTGCTGCTC AGGAACCCGA CTGGACCCCA AGGACAGGCC TGAGAGAAAT 
GGGGCTGCCT TTTTCAGAAT GAAGCAGCAG GTATGGGGGG CCCTCACCAA CTTGGGCTCG 
GCACTGCCCT GTGGCTCCCT CAGTAACTAC AAGCTACCCT GGGTGACAGT TTCTCATCAC 
GATCCAGAGG TCCCCTTCAA CCATAGCTTC ATCGAGCCCC CCTCTGCCGG CTGGGCCTCT 
GACGACTCCT TCTCTTCTGA TCCTGACTCT GGAGAAGAGG ACGAAGCTCA TGCCTACTTC 
GTGCCGCCTC GAGAAGAGAT GGTCCCTATG GCCCAAGAAG AGTCACCAGA AGCCAGCCTT 
CCTGGAGGCT CCTTCCCTCC CCCTGAGGAT GCCTCCACAC CATTCCCCAT TCCACGTACC 
TCCAGCCTGG CTAGGGCCAA GAGGCCATCC GTCTCCTTTG CTGAAGGCAC GAAGTTTGCA 
CCACAGAATG GCCGAAGCTC TGGGGATCTC TCCAGCCCCA TACGAAAACC CAAGAGACTC 
TCCAGAGGTG CTCAACCCCG TCCTGAAGGG CAGGAGGCGG AGGAGTCTAC AGGCCCAGAG 
CAAGTGAACA CAGAGGAGGA TGCTCCTACG GCCACAAGCT CTGGAGATCC TGCCACTAGT 
CACGGCCAAC TTCCACCTGG TAGCCAGATG GTAGCTGAGT GTGCGGAGAC CACTGATGGA 
GGCATCCAGG AGAGCTCAGG ATCTGTGGCC ACTATCTATA TGCTGGCAGG GACACCTCAG 
AAACCTGAGG GTCCTGTCTG GTCTGTCTTT CGTCGTTTGG GAAACTACCA GAAAGATCAG 
ATGGATCCCA AAGTAAAGAG TGCTATCCCT AAGCCTCTGC GCCGATCTCT GGGTCGGAAC 
CAGGCCAGCG CTGGCTCAGC TCCAGGTGCT GTGCTCTCCC AGGCCATGGA GTCCACCGCA 
GTTAGACCAG AGGAAACACC CAGAGGTCTG GGAGATGGCA TTGAGAGCTC AGGGACTGTC 
CAGGAGCCAG ACGCTGGAGG CAGTTCCCTG GAACAGGATT CCCAGAAGCA GGCGGAAGAG 
AAGGAGCAAG AGGAGCCCCT GTATGAGAAT GTTGTGCCCA TGTCCGTGCC GCCACAGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Scavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 264.7 cells upon LPS activation.
PloS one10(4)e0122529(2015)
Murshid A,Gong J,Prince T,Borges TJ,Calderwood SK

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.
Nature immunology14(9)917-26(2013 Sep)
Ramirez-Ortiz ZG,Pendergraft WF 3rd,Prasad A,Byrne MH,Iram T,Blanchette CJ,Luster AD,Hacohen N,El Khoury J,Means TK

Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.
Journal of immunology (Baltimore, Md. : 1950)185(5)2903-17(2010 Sep)
Murshid A,Gong J,Calderwood SK

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36.
The Journal of experimental medicine206(3)637-53(2009 Mar)
Means TK,Mylonakis E,Tampakakis E,Colvin RA,Seung E,Puckett L,Tai MF,Stewart CR,Pukkila-Worley R,Hickman SE,Moore KJ,Calderwood SB,Hacohen N,Luster AD,El Khoury J

Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(52)14404-14(2007 Dec)
Hasegawa H,Abbott S,Han BX,Qi Y,Wang F

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Scarf1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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