Obscn cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Obscn
Entrez Gene ID	380698
Full Name	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms	BC046431,Gm878,UNC89
General protein information	Preferred Names obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF Names obscurin obscn obscurin-MLCK obscurin-RhoGEF obscurin-myosin light chain kinase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B1.3
Summary	The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 800 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein is one of three giant sacromeric signaling proteins that includes titin and nebulin. It may have a role in the organization of myofibrils during assembly and also may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been described although the full-length nature is not known for all splicing variants. [provided by RefSeq, Jan 2010].

mRNA and Protein(s)

mRNA	Protein	Name
NM_199152.3	NP_954603.3	obscurin isoform 2
NM_001171512.2	NP_001164983.2	obscurin isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	OBSCN	NP_001258152.2
Xenopus tropicalis (tropical clawed frog)	LOC101730564	XP_004915765.1
Rattus norvegicus (Norway rat)	Obscn	XP_006246598.1
Pan troglodytes (chimpanzee)	OBSCN	XP_514255.4
Mus musculus (house mouse)	Obscn	NP_001164983.2
Danio rerio (zebrafish)	LOC572412	XP_005162931.1
Gallus gallus (chicken)	OBSCN	XP_418501.4

Gene Ontology
Bibliography

Related articles in PubMed

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.
Ackermann MA, King B, Lieberman NAP, Bobbili PJ, Rudloff M, Berndsen CE, Wright NT, Hecker PA, Kontrogianni-Konstantopoulos A
Journal of molecular and cellular cardiology11127-39(2017 Oct)

Deregulated Ca
Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A
Science advances3(6)e1603081(2017 Jun)

Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice.
Randazzo D, Blaauw B, Paolini C, Pierantozzi E, Spinozzi S, Lange S, Chen J, Protasi F, Reggiani C, Sorrentino V
American journal of physiology. Cell physiology312(1)C16-C28(2017 Jan)

The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.
Ford-Speelman DL, Roche JA, Bowman AL, Bloch RJ
Molecular biology of the cell20(17)3905-17(2009 Sep)

Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.
Lange S, Ouyang K, Meyer G, Cui L, Cheng H, Lieber RL, Chen J
Journal of cell science122(Pt 15)2640-50(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Altogether, these results suggest that obscurin is required for the maintenance of morphological and ultrastructural integrity of skeletal muscle fibers against damage induced by intense mechanical stress and point to the diaphragm as the skeletal muscle most severely affected in obscurin-deficient mice.
Title: Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice.

obscurins are not restricted to striated muscles, but are abundantly expressed in several tissues and organs including brain, skin, kidney, liver, spleen, and lung.
Title: Obscurins: Goliaths and Davids take over non-muscle tissues.

the obscurin kinase domains, SK1 and SK2, are active enzymes with distinct substrate specificities.
Title: The kinase domains of obscurin interact with intercellular adhesion proteins.

Obscurin, by targeting ankB at the M band, contributes to the organization of subsarcolemma microtubules, localization of dystrophin at costameres, and maintenance of sarcolemmal integrity.
Title: Obscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity.

the organization of obscurin at different locations in the sarcomere changes during muscle development and that this might affect the interaction with ank1.5.
Title: Localization of ank1.5 in the sarcoplasmic reticulum precedes that of SERCA and RyR: relationship with the organization of obscurin in developing sarcomeres.

The following Obscn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Obscn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09385	NM_199152.3 Latest version!	Mus musculus obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price
OMu11845	NM_001171512.2 Latest version!	Mus musculus obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Obscn ( NM_199152.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_954603.3 Mus musculus obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), transcript variant 2, mRNA.

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CloneID	OMu09385
Clone ID Related Accession (Same CDS sequence)	NM_199152.3
Accession Version	NM_199152.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 22491bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	obscurin isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL645854.10 and AL662809.14. On or before Oct 10, 2012 this sequence version replaced XM_003945907.1, NM_199152.2. Transcript Variant: This variant (2) represents the shorter transcript and encodes the shorter protein (isoform 2). The RefSeq Project created this record to better support genomic annotation of the full gene length but the combination of exons and splice sites still needs to be experimentally confirmed. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The genomic coordinates used for the transcript record were based on genomic predictions and alignments of transcripts from different species. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACCACT CCTTCAGCGG AGCACCCCGC TTCCTGACGC GGCCAAAGGC CTTTGTGGTA 
TCTGTTGGCA AGGATGCCAC GCTGAGCTGC CAGATCGTGG GCAACCCCAC GCCACACGTG 
AGCTGGGAGA AGGACCGGCA GCCAGTAGAG GCAGGAGCGC GCTTCCGCCT GGCCCAGGAC 
GGGGATGTGT ACCGCCTCAC AATTCTCGAT CTGGCGCTAG GTGACAGCGG GCAGTATGTG 
TGTCGCGCGA GGAACGCCAT AGGGGAGGCC TTCGCCGCCG TCGGCCTGCG AGTGGACTCG 
GAGGGCACGT GTGCCGAGCA GGCGCCCCAC TTTCTGCTGC GGCCCACATC CATTCGCGTG 
CGCGAGGGCG CAGACGCCAC CTTCCGATGT CGCGTTGGAG GCTCACCACA ACCTGCTGTG 
AGCTGGTCCA AAGATGGGCG GCGCCTGGGC CCACCCGATG CCCCCCATGT GCGTGTGGAA 
GAACACGGGG AGTCGAGCGC GCTTCGCATC CGTTCGGCAA GGCCTCGCGA TGGTGGCACC 
TACGAAGTCC GAGCAGAAAA TCCGCTGGGC TCTGCCAGCG CTGCCGCCGC TCTGGTGGTG 
GACTCGGACG CCGAGGTTGC CGGACCACCC GGCACCTCCA CCGCCACGCT CCTGGCGCAC 
CTGCAGCAGC GGCGGGAGGC CATGCGCGCA GAGGGCATAC CCCCTTCTCC ACCCGGCGCT 
GGCACGCGCA CCTGCACGGT GACCGAAGGC AAACACGCGC GCCTCAGCTG TTTTGTGACC 
GGCGAGCCCA AGCCCGAGAC AGTGTGGAAG AAGGACGGGC AGCTGGTGAC CGAGGGCCGG 
CGACACGTAG TGTATGAGGA CGAGCAAGAG AACTTCGTCC TTAAGATTCT TTTCTGCAAG 
CAGTCCGACC GCGGCCTCTA CACCTGCACA GCGTCCAACC TCGTGGGCCA GACCTACAGC 
TCGGTGCTGG TGGTCGTGAG AGAGCCGACG GTGCCCTTCA AGAAGCGGCT GCAGGACCTG 
GAGGTACGAG AGAAAGAGTC TGCTACATTC CAGTGCGAGG TGGCTCAGCC AGCTACCGAG 
GCGGCGTGGT TCAAGGAGGA GACCCGGCTA TGGGCCAGCG CCAAGTACGA CATCGAGGAG 
GAGGGCACCG AGCGCCGGCT GACCGTGCGC AACGTCTCGG CAGACGACGA CGCTGTGTAC 
ATCTGCGAGA CCACAGAGGG CAGCCGCACG GTGGCAGAGC TCTCTGTTCA AGGAAACTTG 
ACCAGAAAGC TGCCTCGGAA GACAGCAGTG CGCACTGGAG ACACAGCCAT CTTTTGGGTG 
GAGCTGGCTG TCCCCGAAGG CCCTGTCCGG TGGCTACGGA ACCAGGAGGA GATGGTGGCA 
GGGGGTCGGG TTGCCATCAC TGCAGAAGGC ACGTGCCACA CACTGACCAT CTTCCAGTGC 
ACCTTGGAGG ACATGGGTGA GGTGGCCTTT GTGTCTGGTG GCTGCCGGAC GACCACCCAG 
TTCTGTGTAT CAGCGCCCAG GAGGCCACCC CTGTACCCTC CTGCTGACCC TGTTGTAAAG 
GCCAAGACAG AGAGTTCTGT GACCCTCAGC TGGTCCGCAC CACCCCATGG GGACCGCCCT 
GTCACTATTG ATGGCTATGT GTTGGAGAAG AGGAAGCTGG GTGCCTATGC CTGGAGCAGG 
TGTCACGAAG CTGGATGGCT GGCCACAACT GAGTTTACCA TCACTGGTGT GGCTGAGGAG 
GGGGATTTCC AGTTCCGAGT GTCAGCCATC AATCACTTTG GCCAGGGTCC TTACCTTGAA 
TTTCCAGGGA CCATGCACTT GGTCCCCATG CTGGCTGTAA AGACACCTCT GAAGGCGGTG 
GAGGCAGTGG AGGGTGGTGA GGTCACTTTC TCCGTGGACC TCACGGTGGC CTCTTCGGGC 
GAATGGTTCC TGGATGGGGA GGCCTTGAAA GCGAGCAGTA TATACGTGAT CCGTTGTGAC 
CGCACCCGGC ATATGCTCAC CATCAGAGAG GTGCCCGCCA GATTGCATGG GGCACAGCTG 
AAGTTTGTGG CTAATGGCAT TGAAACTAGC ATCCAAATGG TGGTCCGAGC GGCTCTGGGG 
CTGCCCAGCA GTAAGCTTCC TGCTGCGGCT GCCCGGGAGG TGCTGGCCCA GTTGCACGAG 
GAGGCACAGC TGCTGGCTGA GCTGTCGGAC CAGGCTGCTG CTGTGACTTG GCTGAAGGAT 
GGTCGTGAGC TGTCCCTAGG GCCCAAGTAT GAGATGCAGG TGTCAGCTGG GAGGCGAGCA 
CTGCTGGTGC GGGACGTGGC ACAGGATGAC GCTGGCCTCT ATGAGTGTGT CAGTCGTGGG 
AGCCGCACTG CCTACCAGCT GTTGGTGCAA GAACCCAAGC TGGTGTTTGC CAAGGGGCAG 
CAGGCACACA GCGAGGTGAA GGCAGAGGCG GGGAACAGCG CCACCCTGAG CTGCGAGGTG 
ACCCAGGCCC AGACTGAGGT GACATGGTTC AAGGATGGGA AGAAGCTGAG CTCCAGCTCG 
AAGGTGCGCA TGGAGGCCTC GGGCTGCTCC AGGAGGCTGG TGGTGCAGCA GGCGGGCAAG 
GCGGATGCTG GGGAGTACAG CTGCGAGGCC GGGGGACAGA AGCTCTCCTT CCGCCTGGAC 
GTGGCAGAAC CCAAGCTGGT ATTTGCCAAG GGGCAGCAGG CACACAGTGA GGTGAAGGCA 
GAGGCGGGGG CCAGCGCCAC ACTGAGCTGC GAGGTGGCCC AGGCCCAGAC TGAGGTGACA 
TGGTTCAAGG ACGGGAAGAA GCTGAGCTCC AGCTCGAAGG TGCGCATGGA GGCCTCGGGC 
TGCTCCAGGA GGCTGGTGGT GCAGCAGGCG GGCAAGGCGG ATGCTGGGGA GTACAGCTGC 
GAGGCCGGGG GACAGAAGCT CTCCTTCCGC CTGGACGTGG CAGAGCCCAA GATGGTGTTT 
GCCAAGGAGC AGCAGGCACG CAGCGAGGTG AAGGCCGAGG CGGGGGCCAG CGCCACACTG 
AGCTGCGAGG TGGCCCAGGC TCAGACTGAG GTGACATGGT TCAAGGACGG GAAGAAGCTG 
AGCTCCAGCT CGAAGGTGCG CATGGAGGCC TCGGGCTGCT CCAGGAGGCT GGTGGTGCAG 
CAGGCGGGCA AGGCAGATGC TGGGGAGTAC AGCTGCGAGG CCGGGGGACA GAAGCTCTCC 
TTCCGCCTGG ACGTCACAGA GCCCAAGCTG GTGTTTGCCA AGGAGCAGCA GGCACGCAGT 
GAGGTGAAGG CAGAGGTGGG GAACAGTGCC ACACTGAGCT GCGAGGTGGC CCAGGCCCAG 
ACTGAGGTGA CATGGTTCAA GGACGGGAAG AAGCTGAGCT CCAGCTCGAA GGTGCGCATG 
GAGGCCTCGG GCTGCTCCAG GAGGCTGGTG GTGCAGCAGG CGGGCAAGGC GGATGCTGGG 
GAGTACAGCT GCGAGGCCGG GGGGCAGAAA CTCTCCTTCC GCCTGGACGT GGCAGAACCC 
AAGCTGGTGT TTGCCAAGGA GCAGCAGGCA CGAAGTGAGG TGAAGGCAGA GGCAGGGAAC 
AGTGCCACAC TGAGCTGTGA GGTGGCCCAG GCACAGACTG AGGTGACATG GTTCAAGGAC 
GGGAAGAAGC TGAGCTCCAG CTCAAAGGTG CGCATGGAGG CCTCGGGCTG CTCCAGGAGG 
CTGGTGGTGC AGCAGGCGGG CAAGGCGGAT GCTGGGGAGT ACAGCTGCGA GGCCGGGGGA 
CAGAAGCTCT CATTCCATCT GGACGTCACA GAACCCAAGC TGGTGTTTGC CAAGGAGCAG 
CAGGCACACA GTGAGGTGAA GGCAGAGGCG GGGGCCAGTG CCACCCTGAG CTGCGAGGTG 
GCCCAGGCCC AGACTGAGGT GACATGGTTC AAGGACGGAA AGAAGCTGAG CTCCAGCTCA 
AAGGTGCGCA TGGAGGCCTC GGGCTGCTCC AGGAGGCTGG TGGTGCAGCA GGCGGGCAAG 
GCGGATGCTG GGGAGTACAG CTGCGAGGCC GAGGGACAGA AGCTCTCCTT CCGCCTGGAC 
GTGGCAGAGC CCAAGCTGGT GTTTGCCAAG GAGCAGCAGG CACGCAGCGA GGTGAAGGCA 
GAGGCTGGGG CCAGTGCCAC ACTGAGCTGT GAGGTGGCCC AGGCCCAGAC TGAGGTGACA 
TGGTTCAAGG ACGGGAAGAA GCTGAGCTCC AGCTCGAAGG TGCGAGTGGA GGCCTCGGGC 
TGCTCCAGGA GGCTGGTGGT GCAGCAGGCG GGCAAGGCGG ATGCTGGGGA GTACAGCTGC 
GAGGCCGGGG GCCAGAAGCT CTCCTTCCGC CTGGACGTCG CAGAGCCCAA GCTGGTGTTT 
GCCAAGGAAC AGCAGGCAAA CAGCGAGGTG AAGGCCGAGG CGGGGGCCAG CGCCACACTG 
AGCTGCGAGG TGGCCCAGGC CCAGACTGAG GTGACATGGT TCAAGGACGG GAAGAAGCTG 
AGCTCCAGCT CGAAGGTGCG CGTGGAGGCC TCGGGCTGCT CCAGGAGGCT GGTGGTGCAG 
CAGGCGGGCA AGGCGGATGC TGGGGAGTAC AGCTGCGAGG CCGGGGGGCA GAAGCTTTCC 
TTCCGCCTGG ACGTGGCAGA GCCCAAGCTG GCGTTTGCCA AGGAGCAGCA GGCACACAGC 
GAAGTGAAGG CAGAGGCGGG GGCCAGCGCC ACACTGAGCT GCGAGGTGGC CCAGGCCCAG 
ACTGAGGTGA CATGGTTCAA GGATGGGAAG AAGCTGAGCT CCAGCTCGAA GGTGCGCGTG 
GAGGCCTCGG GCTGCTCCAG GAGGCTGGTG GTGCAGCAGG CGGGCAAGGC GGATGCTGGG 
GAGTACAGCT GCGAGGCCGG GGGACAGAAG CTCTCATTCC GCCTGGACGT GGCAGAGCCC 
AAGCTGGCGT TTGCCAAGGA GCAGCAGGCA CACAGCGAGG TGAAGGCAGA GGCGGGGGCC 
AGCGCCACAC TGAGCTGTGA GGTGGCCCAG GCCCAGACTG AGGTGACATG GTTCAAGGAC 
GGGAAGAAGC TGAGCTCCAG CTCGAAGGTG CGCGTGGAGG CCTCGGGCTG CTCCAGGAGG 
CTGGTGGTGC AGCAGGCGGG CAAGGCGGAT GCTGGGGAGT ACAGCTGCGA GGCCGGGGGT 
CAGAAGCTCT CCTTCCGCCT GGACGTGGCA GAGCCTAAGC TGGCGTTTGC CAAGGAACAG 
CAGGCACACA GCGAGGTGAA GGCAGAGGCG GGGGCCAGTG CCACACTGAG CTGCGAGGTG 
GCCCAGGCCC AGACTGAGGT GACATGGTTC AAGGACGGGA AGAAGCTGAG CTCCAGCTCG 
AAGGTGCGCG TGGAGGCCTC GGGCTGCTCC AGGAGGCTGG TGGTGCAGCA GGCGGGCAAG 
GCGGATGCTG GGGAGTACAG CTGCGAGGCC GGGGGACAGA AGCTCTTCTT CCGCCTGGAT 
GTGGCAGAGC CCAAGCTGAT GTTTGCCAAG GAGCAGCAGG CACACAGCGA GGTGAAGGCA 
GAGGCTGGGG CCAGCGCCAC ACTGAGCTGC GAGGTGGCCC AGGCCCAGAC TGAGGTGACA 
TGGTTCAAGG ACGGGAAGAA GCTGAGCTCC AGCTCGAAGG TGCGCGTGGA GGCCTCGGGC 
TGCTCCAGGA GGCTGGTGGT GCAGCAGGCG GGCAAGGCGG ATGCTGGGGA GTACAGCTGC 
GAGGCCGGGG GGCAGAAGCT CTCCTTCCGC CTGGATGTGG CAGAGCCCAA GCTGGTGTTT 
GCCAAGGAGC AGCAGGCACA CAGTGAGGTG AAGGCCGAGG CGGGGGCCAG CGCCACCCTG 
AGCTGCGAGG TGGCCCAGGC CCAGACTGAG GTGACATGGT TCAAGGACGG GAAGAAGCTG 
AGCTCCAGCT CGAAGGTGCG CGTGGAGGCC TCGGGCTGCT CCAGGAGGCT GGTGGTGCAG 
CAGGTGGGCA AGGCGGATGC TGGGGAGTAC AGCTGCGAGG CCAGGGGACA GAAGCTCTCC 
TTCCGCCTGG ACGTGGCAGA CACCAGGCTG ATGTTTGCCA AGGAGCAGCA GGCACGCACC 
GAGGTGAAGG CTGAGGCGGG GAACAGTGCC ACCCTGAGCT GCGAGGTGGC CCAGGCCCAG 
ACTGAGGTGA CATGGTTCAA GGACGGGAAG AAGCTGAGCT CCAGCTCGAA GGTGCGCGTG 
GAGGCCTCGG GCTGCTCCAG GAGGCTGGTG GTGCAGCAGG CGGGCAAGGC GGATGCTGGG 
GAGTACAGCT GCGAGGCCGG GGGTCAGAAG CTCTCCTTCC GCCTGGACGT GGCAGAGGCC 
GAATCCCAGA TTCCGGAGAG ACCCAGCCGC AGGGAACCTC TGGTTGTCAA GGAACATGAG 
ACCATTATCC TGACTGCCAC AATAGCTGCA CCCTCTGTGG CTGCTGTGAC CTGGCTCAAA 
GATGGAGTGG AGATCCGCCG CAGTAAGCGG CATGAGGCCA CCAGTCTGGG TGATACCCAT 
ACCCTGACCG TGAGAGGCGC ACAGGTCCTG GACAGTGCCA TCTACAGCTG CCGTGTTGGC 
AAGGAAGGTC AGGACTTCCC GGTGCAGGTA GAAGAGGTGG CCGCCAAGTT CTCCAAACCC 
CTGGAGCCCG TCGAAGGGGA GCTGGGTGGC ACCGTGATGC TGGTTTGTGA GCTGAGCCCG 
GAGCAGGCTG AGGTTGTGTG GCGCTGTGGG AACACACAGC TGCGGCCAGG CAAGCGCTTC 
CAGATGACAT CAGAGGGGCC TAGGCGCACG CTGACCGTGT CTGGCCTTCG AGAGGATGAC 
GCAGAGGAGT ATGTGTGTGA GAGCCGGGAT GACCGCACCA GCGCACGGCT CACTGTTAAA 
GTTCCCCGAG TGGTCAAGTT TACGTCTGGA TTGAGTGCCA TGGTCGCAGA GGAGGGCCAA 
GAGGCCACCT TTCAGTGTGT CGTGTCCCCC AGCGATGCAG GGGTCACATG GTACAAGGAC 
GGGATGCAGC TGCAGCCTAG CGAGAAGTTT GTTATGGTAG AGAGTGGGGC CAGCCGCAGC 
TTGACTATCT TGGGCCTGAC CCTGGAGGAT GCCGGTCAAG TCACAGTGGA GGCTGAGGGG 
GCTTCATCTT CTGCTGCCCT CCGGGTCCGA GAGGCACCGG TCCTCTTCAA AAAGAAGCTG 
GAGCCACAGA CAGTGGAGGA GAGGACCTCT GTGACATTGG AGGTGGAGCT GACGCGGCCC 
TGGCCCGAGG TGAAGTGGAC ACGGAATGCT GCCGTCCTGA CACCCAGCGA GAACGTGGAG 
ATCCGCGCTG AGGGTGCTCG GCACTGTCTG GTGCTGCGCA GCGTGGGCTT TGCTGACCGC 
GGCTTCTTTG GCTGTGAGAC ACCAGATGAT AAGACTCAGG CCAAGCTCAA TGTAGAAATG 
CGGCAGGTCC GGCTGGTTCG CGGTCTGCAG GAGGTGGAGG CTAAGGAACA GGGCACGGCC 
TCGATGGATG TGGAGCTGTC CCATGCCGAG GTGGAGGGCA GCTGGACCCG AGATGGCCTG 
CGACTTCAGC CTGGACCCAA ATGCCACCTG GCCGTACAAG GCCCTGTCCA CATCCTCACA 
CTCTCGGCGC TGCAGCCACA GGACAGTGGG CTGGTGGCCT TCAGGGCCGA GGGCGTGCAC 
ACGTCTGCGA GGCTCATAGT CACTGAGTTG CCCGTGAGCT TCACCAGAGT ACTACAGGAT 
GTGGTGGCCA CGCAGAAGGA GAAGGTCACC CTGGAGTGTG AGCTGTCGAG GCCTGTGGAT 
GTGCGCTGGC TGAAGGATGG TGTGGAGCTG CGGGCAGGCA AGGCCATAGG CATAGTGGCC 
CAGGGAACCT GCAGGAGTCT CGTTATCTAC CGCTGTGAGA CTGGGGACCA GGGTGTCTAT 
GTATGTGATG CTCTTGATGC TCAGACCTCT GCCTCTCTGA GGGTGCAAGG GAGGACATAC 
ACGCTTATCT TCCGGAGGGT ACTGGCAGAG GATGCAGGGG AGGTCAAGTT TGTAGCTGAG 
AACGCAGAAT CAAGAGCTCA CCTCCGAGTG AAAGAACTGC CCGTGACCCT CCTGCGCCCA 
CTGAGGGACA AGATTGCCAT GGAAAAACAC CGTGGAGTGC TGGAGTGCCA GGTGTCCCGG 
GCTAGTGCCC AGGTGCGGTG GTTCAAGGGC GGAGTCGAGC TGCAGTCTGG GCCCAAGTAC 
GAGGTGGTCA GTGACGGCCT TTACCGCAAG CTGGTCATTA ATGACGTGCA GCCTGAGGAT 
GAAGATACGT ACACCTGTGA CGCTGGCAAC GTCAAGACCA GTGCCCAGTT CTTTGTGGAA 
GAGCAATCCA TCACTATTGT GCGGGGACTG AAGGACATGA CAGTGATGGA GCCTGCCCCT 
GCCTGGTTTG AATGTGAGAC ATCCATCCCT TCCGTGAGGC CACCCAAGTG GCTCCTTGGT 
AAGACTGTGC TCCAGGCAGG GGGGAACGTG GGACTGGAGC AAGACGGCAC CGTGCACCGG 
CTGACACTGC ACAAGACCTG CTCTACCATG ACCGGGCCTG TGCACTTCAC TATCGGCAAG 
TCCCGCTCCT CTGCCCAGCT GGTTGTCTCA GACATTCCTG TGGTACTGAC ACGGCCTCTG 
GAGCCCAAAG CAGGGCGTGA ACTGCAGTCA GTAGTCCTGT CCTGTGACTT CAGGCCAGCC 
CCCAAGGCTG TGCAGTGGTA CAAGGATGAC ACACCCCTGT CCCCGTCAGA AAAGTTCAAG 
ATGGCGCTGG AGGGCCAGAT GGCAGAGCTG CGCATACTCC GGCTCACGCC AGCTGATGCT 
GGGGTCTACC GGTGCCAGGC GGGTAGCGCC CAGAGCAGTG CTGAGGTTAC TGTGGAAGCT 
CGGGAGGTGA CAGTGATTCA GCCACTGCAG GATGCAGAAG CCATGGAGGA AGGCCGGGTC 
TGCTTCTCCT GCGAGCTGTC CCATAAGGAT GAAGATATCG AATGGTCACT CAATGGTACA 
CCCCTGTACA ATGACAGCTT CCATGAGATC AGCCATGAGG GCTGTCTCCA CACCCTGGTG 
CTGAAGAGTG TCCGGCAGGC TGACACAGGC ACCGTGTGCG CCACCTCCCC CAAGGTGTCC 
GTTTCCGCCC GGCTGGTGGT TAAAGGCAAG CCAGTGGTGT TCCTGAAAGC ACTGGATGAC 
GTATCTGCAG AAGAGCGTGG CACGCTGACC CTGCAATGCG AGGTCTCCGA CCCCGAGGCA 
CGCGTGGTTT GGCGCAAAGA TGGTGTGGAG CTTGGTCCCA GCGACAAGTA TGATTTCCTA 
CATAAGGCAG GTGCCCGGGG CCTTACGGTC CATGACCTGA GCCATGAGGA TGCTGGACTG 
TACACCTGCC AGGTGGGCAG TAAGGAGACC CAGTCCAAGG TCAGCGTACA TGATCTTCAC 
GTGGGCATCA CCAAGAGGTT AAAGACAGTG GAGGTGCTGG AGGGAGAGAG CTGCAGCTTT 
GAGTGTGTCC TTTCCCACGA GAGTCCCAGT GACCCAGCAG TGTGGACGGT CGGTGGGAAG 
ACAGTGGGTG GTTCTGGCCA CTTTCACGCC GTTCGGCAGG GCCGCAAATA CACCCTGACA 
GTCAAAGATG CTGCACTCAG TGATGCAGGA GAGGTGGTCT TCTCGGTGCT GGGCCTCACT 
TCCAAGGCCT CGCTCATCAT CAGAGAGAGG CCAGTGGACA TCACCAAGCC CCTGGAGGAC 
CAGCGGACGA CGCTTGGGGA AGATGTAATG CTAAGCTGTG AGCTGTCCAG GGCAGGCACC 
TCTGTGCGCT GGCTGAAAGA CGGGAAGGCC ATCAGGAAGA GCCAGAAGTA TGACCTGCTC 
AGTGAAGGCA CGCGGGCTGT GTTGGTTGTC CGCAAGGCCT CACTCAAGGA TTCAGGGGAA 
TACACCTGCG AGACAGAAGC TTCGAAAAGC ACTGCCAAGC TCTGTGTGGA AGAAAAGGCA 
AACCGGTTCA CGGAGGAGCT GGCTGACCTG CAGGTGGAAG AGAAGGGCAG AGCTGTGTTC 
ACATGCAAGA CAGAGCACCC AGCATCTGTC GTGACCTGGC GCAAAGGCCT CCTGGAGCTG 
CGCGCCTCAG GGAAGCATGT CCCCAGTCAG GAAGGCTTGA CCCTGAAGCT CACCATCAAC 
GCCCTGGAGA GGACAGACAG TGACACTTAC ACCTGTGACA TCGGCCAAGC CCGGACCCAG 
GCACGGCTCC TCGTCCACGG CCAGAAAGTG CGCGTTATTG AGGACCTAGA GGACACTGCT 
GTCCAGGAGG GCTCCTCTGC TAAGTTTTGC TGCCGCATCG CTCCTGCTGA CTACGGCCCC 
GTGCACTGGT TCCTGGATAA GACCCCCTTG CACAGCAATG AGCTGAATGA GATCACTGTC 
CAGCCTGGAG GCTATCACGT GCTCACCCTG CGGCAGCTGG CACTCAAGGA CTCAGGCACT 
GTCTACTTTG AGGCGGGTGA CCAGCGAACC TCAGCTGCCC TGCGGGTGAC TGAGAAGCCG 
AGCATCTTCT CTCGGCCACT CACAGACGTC ACAGTCACAG AAGGCGAGGA CCTGACTCTG 
GTCTGTGAAA CCACCACTGT GGATAGCTCT GTGCGCTGGA CCAAAGATGG GAAGACACTG 
AGGCCGTCTG CACGATGCCA GCTGAGCCAT GAAGGCTGTC AGGCCCAGCT GCTCATCACT 
GCCACCACCC CACAAGATGG TGGGCGGTAC AAATGTGAGA TTGGTGGAGC CTCCAGCAGC 
TCCATTGTCA GGGTCCATGC TCTGCCAGTG CGGTTCAGGG AGTCCCTGAA GGACGTGGAG 
GTACCAGAGG GCAAGGCCGC CACACTGCGC TGTGTGCTGT CATCCGTGGC TGCACCTGTG 
GAGTGGCGTC ATGGAGATGA TGTCCTGAAA TCCAGCAACA AGTATAGCCT GCGCCAAGAG 
GGTGCTGTGC TGGAATTGGT CATCCGAGAC CTGCAGCCCC AGGACAGTGG GCAATACTCA 
TGCTCCTTTG GGGACCAGAC AACTTCAGCC ACACTCACAG TGAAAACCTC TTCTGCCCAG 
TTCGTAGGGA AACTGAGAAA CAAGGAGGCC ACAGAAGGGA CCACGGTCAC ACTTCGGTGT 
GAGCTGACCA AAGAGGCCCC CGTGGAGTGG AAGAAGGGAA CAGAGACCCT GAGAAATGGG 
GACAAATACA GTCTGAAGCA GGATGGAGCT GTGTGTGAGC TGCAGATCTG TAGTCTGCTG 
GTGGCAGATG CAGGGGAGTA CTCGTGTGTG TGTGGGCAGG AGAAGACTTC AGCCACGCTG 
ACTGTCAAGG CTCTGCTTGT CCACTTTGTC AGAAGGCTCA GGAGCAAGGA GGCCACAGAA 
GGAGACACGA CCACACTGCA GTGTGAACTG AGCAAGGCTG CCCCCGTGGA GTGGAGGAAG 
GGAACAGAGA CCCTGAGAGA TGGGGACAGA TACAGCCTGA AGCAGGATGG GGCTGTGTGT 
GAGCTGCAAA TCCGCAGCCT GACCATAGCA GATGCTGGCG AGTACTTGTG CACGTGTGGA 
CAGGAAAAGA CCTCAGCCAC GCTGACCGTC AGGGCCCTTC CAGCTAAGTT CAAAGACAGT 
CTGAAGAATG AAGAGGCTAC AGAAGGCACC ACAGCTACAC TGAGCTGTGA ACTGAGCAAG 
GCAGCTCCGG TGACATGGAA GAAAGGACCG AAGACCTTGC AAAGTGGAGA CAAATATGTC 
CTGAGGCAGG ATGGAGCTGT GTGTGGACTA CAGATCCATG GCCTGACCAT GGCTGATGCT 
GGGGAGTACT CGTGTGTGTG TGGGCAGGAG AAGACGTCAG CCACGCTGAC TGTCAGGGGC 
TTGCCTGCCA AATTTATAGA AGATCTGAGA AGCCAAGAAG CCACAGAAGG GGCCACAGCA 
ATCTTAAGAT GTGAGCTGAG CAAGGCTGCT CCTGTGGAGT GGAGGAAAGG GTCTGAGACC 
CTGAAAGATG GGGACAGATA CACCCTGAGG CAGGATGGGG CCGTATGTGA GCTGCAGATC 
CGTGGCCTGG CTGTGGTGGA TACTGGGACA TACTCGTCCC TGCCCACCAA GTTCACAGAG 
GGTCTGAGGA ATGAAGAGGC CACGGAAGGC ACCATGGCCA CTCTGAGGTG CCAGATGAGC 
AAGGCTGCCC CTGTGGAGTG GAGGAAGGGG TCAGAGACCC TGAGAGATGG GGACAGATAC 
AGCCTGAGGC AGGATGGGGC CATGTGTGAG CTGCAGATCC GTGGCCTGAC CATAGAAGAT 
TCTGGGGAGT ACACATGTGT GTGTGGGCAG GAGAAGACGT CAGCCACACT GAGTGTCAAG 
GCCCTGCCCT CCAGATTCAT AGAAGATTTG AGAAGTCAAG AGGCCACAGA AGGCACCATG 
GCCACTCTGA GGTGCCAGAT GAGCAAGACT GCCCCTGTGG AGTGGAAGAA GGGGTCTGAG 
ACCCTGAGAG ATGGGGGCAG ATACAGCCTG AGGCAGGATG GGCCTGTGTG TGAGCTGCAG 
ATCTGTGACC TGGCTGTCGA AGACGCTGGG GAGTACTCAT GTGTGTGTGG GCAGGAGAAG 
ACCTCAGCCA CACTGAGTAT CAAGGCTCTG CCCCCCAGAT TCATAGAAGA CTTGAGAAGC 
CAAGAGGCCA CAGAAGGCAC CATGGCCACT CTGAGGTGCC AGATGAGCAA GGCAGCCCCT 
GTGGAGTGGA GGAAGGGGTC TGAAACCCTG GGAGATGGGG GCAGATACAG CCTGAGGCAG 
AATGGTGCTG TGTGTGAGCT GCAGATCCAT GACCTGGCTG TGGAAGACAC TGGGGAGTAC 
TCATGTGTGT GTGGGCAGGA GAAGACCTCA GCCACACTGA ATGTCAAGGC CCTGCCCCCC 
AGATTCATAG AAGACTTGAG AAGCCAAGAG GCCACAGAAG GCACCATGGC CACTCTGAGG 
TGCCAGATGA GCAAGGCAGC CCCTGTGGAG TGGAGGAAGG GGTCTGAGAC CCTGAGAGAT 
GGGGGCAGAT ACAGCCTGAG GCAGGATGGG GCTGTGTGTG AGCTGCAGAT CCATGACCTG 
GATGTGGAAG ATGCTGGCCA GTACTCGTGC GTGTGTGGGC AGGAGAAGAC CTCAGCCGTG 
CTGACTGTAG ATGCACTGCC CCCCAAGTTT ACAGAGGGTC TGAAGAAGGA AGAGGCCACA 
GAAGGGACCA TGGTAACACT GAGGTGCCAG ATGAGCAAAG AAGCCACGGT GGAGTGGAGG 
AAGGGAGCAA AGACCCTCAG CGATGGGGGC AGATACAGCC TGAGGCAGGA TGGGGCCATG 
TGTGAGCTGC AGATCTGTGG CCTGGCTGTG GAAGACGCTG GGGAATACTC ATGTGTGTGT 
GGGCAGGAGA AGACCTCAGC CACACTGAGT GTCAAGGCCC TGCCCCCCAG ATTCATAGAA 
GACTTGAGAA GCCAAGAGGC CACAGAAGGC ACCATGGCCA CTCTGAGGTG CCAGATGAGC 
AAGGCTGCCC CTGTGGAGTG GAGGAAGGGG TCTGAGACCC TGAGAGATGG GGACAGATAC 
AGCCTGAGGC AGGATGGGGC TGTGTGTGAG CTGCAGATCC GTGACCTGGC TGTGGAAGAT 
GCTGGCGAGT ACTTGTGCGT GTGTGGGCAG GAGAAGACCT CAGCCACACT AAGTGTCAAG 
GCCCTGCCCC CCAGATTCAT AGAAGACTTG AGAAGCCAAG AGGCCACAGA AGGCACCATG 
GCCACTCTGA GGTGCCAGAT GAGCAAGGCT GCCCCTGTGG AGTGGAGGAA GGGATCCAAG 
ACCCTGAGAG ATGGGGACAG ATACAGCCTG AGGCAGGATG GGGCCATGTG TGAGCTGCAG 
ATCTGTGACC TGGCTGTGGA AGACACTGGG GACTACTCAT GTGTGTGTGG GCAGGAGAAG 
ACCTCAGCCA CACTGAGTGT CAAGGCCCTG CCCCCTAGAT TCATAGAAGA TTTGAGAAGC 
CAAGAGGCCA GGGAAGGTAC TGTGGCCACT CTGAGGTGCC GGATGAGCAA GGCTGCCCCA 
GTGGAGTGGA GGAAGGGGTC AGAAACCCTG AAAGATGGGG ACAGATACAG CCTGAGGCAG 
GAGGGGAACC TGTGTGAGCT GCAGATCCGT GACCTGGCTG TCGAAGACAC TGAGGAGTAC 
TCATGTGTGT GTGGGCAGGA GAAGACCTCA GCCACACTGA GTGTCAAGGC CTTGCCAGCC 
AAATTCATAG AAGACTTGAG AAGCCAAGAG GCCCCGGAAA GTTCAACAGT CACATTGCGG 
TGTAAGCTAA GCAAGAAGGC CTCTGTGGTG TGGAAGAAAG GGTCTGAGAC CCTAAGAAAT 
GGGGCCAGAT ACAGCCTGAG GCAAGATGGG GCTGTGTGTG AGCTGGAGAT CCGAGACCTG 
ACTGTGGAAG ATACTGGAGA GTACTCGTGC ACATGTGGGC AGGAGAGGAC CTCAGCCACA 
CTGAGCATTA TGGCTCCACA GGTGGTATTC CAGCAGCCAC TGCAGAATCT GCAAGCAGAA 
GAAGGCTCCA TGGCCAGCCT GCGGTGTGAG TTGTCAGTCC CCAACGCTGC CATGGTCTGG 
AGCAAGGGTG GTCTGGAGCT GCAGGGTGAC ACGCGCCGAG AGGCACGGCA GCAGGGGTGT 
GTGGCAGAGC TGTTGCTTAG GGACCTGCGT CGCGAGGATG CGGGCGAGTA CAGTTGCACC 
TGTGGCTCTC AGACCACAAG CGCCACGCTC ATGGTCACAG CTGCTCCTGT GCGGTTCCTC 
CGGGAACTGC AGGCCCAGGA CGTAGATGAG GGGGCCACCG CACGCCTGCG CTGTGAGCTG 
AGCCGGGAGG CTGTGAGCGT GGAGTGGCGC AAGGGCTCCT TGCAACTTTT TCCTTGTGCT 
AAGTATCAGA TGGTGCAGGA GGGCACAACT GCGGAGCTGC TGGTCCATGG GGTGGAGCAG 
GAGGATGCAG GCGAATACAC CTGCGATGCA GGCCACACGC AGAGCATTGC CAGGCTCTCT 
GTCCGAGCCC CCAAGCCCAA GTTCAAGACC GACCTGCAAA GCACAGAGCA GGAAGCAGGT 
GGCACGGCAC GGCTGTGTTG TCAACTGAGC GAAGCTGAGC CAGGGACTCC AGTGCAGTGG 
CTCAAGGAGG GGGTGGAGCT GCACGTCGGC TCCAAGTATG AGATGCGGCG CCAAGGGGCT 
GTGTGCGAGC TGCTGATCCA TGGGCTGGAG GCCAAGGACA CTGGAGAATA TGCCTGCCTG 
GTGGGTGGCC AGAAGACCTT GGCCTCCCTC AGAGTCAAAG AGCCTGAGGT GACCATCGTG 
CGGGGACTCG TGGACATGGA GGTGCAGGCC GATGAGGATG TGGAGTTCAC TTGCAAGGTG 
TCACAGGCAG GAGCCACAGA CGTGCAGTGG CACCTCCAAG GTCTGCCACT GCAGAGCAAT 
GAAGTGACAG AGGTGGCTGT CCTTGCGGAC GGCTGTACCC ATGTGCTCCA GTTAAAGGGT 
GTGACACTGG AGGATGCTGG TACTGTCTCC TTCCACGTGG GCGGCCTTTC ATCTTCTGCT 
CAGCTCACAG TCCGAGTCCC TGAGGTGACC GTTCTGGAGC CCCTGAAGGA TGTGCAGCTC 
AGCGAGGGCC AGGATGCCCA CTTCCGGTGC CGACTGTCCA GGGCCTCGGG CCAGGAGGCT 
CGCTGGGCTT TGGGAGGGGT TCCCTTGCAG TGCAACGAGA TGAACGACAT CACTGTGGAG 
CAGGGCACAC TCTACCTGCT CACTCTGCAC AAGGTGACCC TGGAGGATGC TGGGACCATC 
ACTCTCCAAG TGGGCTCATG CTCCTCAGAG GCCCAGCTGA AGGTCACAGC CAAGAACACG 
GTGTTGCGTG GCCTGGAGAA CGTGGATGCA CTGGAGGGCG GTGAGGCTCT GTTCGAGTGC 
CAGCTGTCCC AGCCTGAAGT GGCCGCCCAC ACCTGGCTGC TGGACGACGA GCCTGTGCAC 
ACGTCGGAGA AGGTGGAGGT GGTCTACTTT GAGAACGGAC TGCGGCACCT GCTTCTACTC 
AAAAACCTGA AGCCACAGGA CAGCTGCCGA GTGACCTTCC TGGCAGGGGA TGTGGTCACG 
TCCGCATTCC TCACTGTGAG AGGCTGGCGC TTGGAGGTCC TAGAGCCCCC ACATGATGCA 
TCTGTGAAAG CTGGTATGCA GGTCCGCTTC ACATGCATAC TAAGTGAGGC GGTGCCTGTG 
GGTGAGGCTA CTTGGTACAT CAACGGGGCT GCCATCCAAC CTGATGACAC TGACTGGACA 
GTCACCACAG ATGGCAGCCA CCATGCCCTG ACGCTGAGCA ATGCCCAGCC CCAACACGCA 
GGAGAGGTCA CATTTGCAGC ACGGGATGCT GTGGCCTCTG CACGCCTCTC TGTGTTGGCT 
CTTCCTGACC CCCCTGAAGA TGCTGAAGTG GTGGGGCGTA GTGACCATTC TGTGACCCTA 
TCCTGGGTGG CTCCCATGAG TGATGGAGGT GGGGGTCTAT GTGGTTATCG TGTGGAGATG 
AAGGAGGCAT CCACAGGCCA GTGGCAGTTG TGCCATGACT TGGTACCTGG TCCAGAGTGC 
GTGGTGGACG ACCTGGTCCC CGGGAAGACC TACCGCTTCC GAGTGGCAGC TGTGGGTCCA 
GCAGGTGCTG GGGAGCCTGT ACACTTGCCC CAGATGGTCA AGATAGCCCC AGCCCCGGCC 
CCGGCCCCGG CCCCTGCCCC AGCCCCTGCC CCAGAAACAC GGCAGGCAGT AGTTGGTGAA 
GACATCTGTC TGGAGTTGGA AGTGGCAGCT GATGGTGGCG AGGTCGTCTG GCACAAGGGA 
ACAGAGCGCA TCCAGCCCGG AGGGCACTTT GAGGTCCTCT CTCGGGGTCA GCGGCAGATG 
CTGGTGATCA AGGGCTTTAG GACCGAAGAC CAAGGGGAGT ACCGCTGTGG TCCCATTCAG 
GGTCTGCCCT CCTCAGGAGC TGCCACGTTC AATGTGGTCA TGACCTCAGG CTCTGGGGAT 
GAGGTCCCGG CACAGCCTAG CCTGCCTCCC GAGGCAGCCC AGGAGGGTGA CCTGCATCTG 
CTTTGGGAGG CCCTTGCCCG GAAGCGCCGC ATGAGTCGGG AGCCCACGCT GGACTCCATC 
AGTGAGCTGC CTGAGGAAGA CAGCCGTGTG CAGCATCTGC GGCAGGAGGC AGAAGAGACA 
GCTCCCGACC TCTCTGAAGG CTACTCTACA GCGGATGAGC TAGCACGCAC AGGAGAGGCC 
GACCTCTCAC ACACCAGCTC TGACGATGAG TCTCGGGCTG GCACCCCTTC CCTAGTTACC 
TACCTCAAGA AGGCCGGGGG TCCTGGGATC TCACCCTTGG CCAGCAAGCA TGAGGCCCAG 
GTGACCACGT CTGTGAAGCC ACAAAAGCAG CAGGAGCCAG TCGTGCCCAC GTGCCCACCG 
CCGGGAGACT TGAGTGCAGC AGATTTGATG GATCCATCCC TGGACAAGGC TGCTGTGAAG 
ATTCAGGCTG CCTTTAAGGG TTACAAAGTG CGGAAGGAGA TGAAACAGCA GGAAGGGCCT 
GTGTTCTCAC GAACATTTGG GGACACAGAG GCACAGGTTG GGGATGTGCT GCGGCTAGAG 
TGTGTGCTGG CCACCAAGAC TGATATGCGG GCCTGCTGGT TGAAGGATGG CATCGAGTTA 
ACAGATGGGC GCCATTACCA CATAGACCAG CTCAAGGATG GTACCTGCTC TCTGCTGGTC 
ACTGGCCTGG CCCCCACTGA CTCTGGCCGT TACACCTGTC AGGTGAGCAC CAAGTCTGGC 
CGTGTGAGCC ACAGTGCCTG CGTGGTGGTC AGTGGGACAG AGAGCGAGGC CGAGAGCTCC 
TCTGGGGGCG AGCTGGATGA TGCTTTCCGC CGGGCAGCGA GACGCCTGCA CCGCCTCTTC 
CGCACCAAGA GCCCAGCTGA GCTTTCAGAG GAGGAACTCT TCCTCAGCGC TGATGAAGGC 
CCCGGGGAGC CAGAGGAGCC CGCAGACTGG CAAACATACC GAGAGGATGA GAACTTTGTG 
TGCATCCGTT TTGAGTCCCT TGCAGAGGCC CGCCAGGCAG TCACCTGCTT CCGAAACATG 
TTTGCCACTA TGGGCATCGG GGTGGAGATC AGCCTAGGGG AGCAGGGACC CCGGGGAGTG 
GAGATGCGCA TCGGCAAGGT GGCCCCTACT GTCACCCCTG CAGTGCCGCT TGCAAAGACA 
CCTGGCCTGC AGACTTCAGA TGCTGCCCCA GTGTTCCTGA CCGAGCTGCA GAACCAAGAT 
GTGCAGGATG GATACCCCAT GAGCTTCGAC TGCGTGGTAA CGGGCCAGCC TGTGCCCAGT 
GTGCGCTGGT TCAAGGATGG GAAGCTGCTA GAAGAGGATG ACCACTATAT GATCAATGAG 
GACCAACAGG GGGGTCACCA GCTCATCATC ACAGCTGTGG TGCCGGCAGA CATGGGTGTC 
TACCGCTGCC TGGCGGAGAA CAGCATGGGC GTCTCCTCCA CCAAGGCTGA GCTTCGTGTG 
GAATTGACCA GCACAGACTA TGATACTGCT GCGGATGCTA CTGAGACCTC ATCCTACTTC 
AGCGCCCAGG GATACCTGTC CAGTCGGGAG CAAGAGGGAA CGGAGTCAGA TGAGGGGCAG 
CTTCCCCAGG TGCTGGAGGA ACTGAAAGAC CTCCAAGTGG CCCCCGGGAC ACGCCTGGCC 
AAGTTCCAGC TCAAGGTGAA AGGCTATCCA GCTCCCAAAC TGTATTGGTT CAAAGATGGC 
CAGCCCCTGA CCACGTCTGA CCACATCCGC ATGACTGACA AGAAGACCCT GCACACCCTG 
GAGATTGTCT CGGTCACTCG GGAGGACAGC GGCCAGTATG CAGCCTACAT CAGCAATGCT 
GTGGGTGCTG CCTATTCGTC AGCCCGGCTT CTGGTCCGAG GTCCCAGTGA ACCAGAAGAG 
AAGCCAGCAT CAGATGTTCA TGAGAGGCTG GTGCCACCCC GAATCCTGGA GAAGTTCACC 
CCCAAGAAAG TGAAGAGGGG CTCCAGCATC ACCTTTTCAG TGAAGGTGGA AGGACACCCG 
GCCCCCAGTG TGCATTGGCT CAAGGAGGAG GCAGAGAAGG GAGTCCTGTG GATTGGCCCT 
GACACCCCGG GCTACACCAT GGCCAGCTCT TCCAAGCAGC ATAGCCTGGT CCTGCTGGAC 
GTAGGCCGAC AGCACCAGGG CACCTACACA TGTATTGCTA CCAACCCTGC TGGCCAGGCG 
CTCTGCTCTG CCAGCCTGCA CATCTCTGGC TTGGCCAAAG AAGAAGAGCA GGAGAGAGTG 
AAGGAGGCCC TCATTTCCTC TTTCCTGCAA GGGACAAGCC AAGCTGTCTC AGCCCAGATG 
TCAGAATCCG CAGGTTTTGC TGATCTTGTC GGGCAAAGCA AAGGCGAGTC TCTGGTGGCT 
GAGGAGGCCC ACAGTCACCT GTCCCTTGCT GAGGTGGGCA CTGAAGAGTT CCTGCAGAAA 
CTCACCTCGC AGATCACGGA GATGGTATCG GCCAAGATCT CTCAGGCCAA ACTCCAGGTG 
CCTGGAGGTG ACAGCGATGA AGAGACCAAG ACACCATCTG CTTCTCCTCG GCATGGCCGG 
TCACGTCCTT CCTCCAGTGT TCAAGAGTCC TCCTCAGAGT CAGAGGATGG GGACTCCCGT 
GGTGAGATCT TTGACATCTA TGTGGTCACA GCTGACTATC TGCCACTGGG AGCTGAGCAG 
GATGCCATCA TTCTGAGAGA AGGCCAGTAT GTGGAGGTCC TTGACTCTGC CCATCCCCTG 
CGCTGGCTTG TCCGGACCAA GCCCACCAAA TCCAGTCCTT CCAGGCAGGG CTGGGTGTCA 
CCTGCCTACC TGGATAAGAG GCTCAAGCTG TCTCCTGAGT GGGGGCCCAC TGAGGCCCCC 
GAGTTCCCTG GCGAGGCTGT GTCTGAGGAT GAGTATAGAA CGAGGCTGAG CTCTGTCATC 
CAGGAGTTGC TGAGTTCAGA GCAGGCTTTT GTGGGTGAGC TGCAGTTCTT GGAGAGCCAC 
CACATGAAGC ACCTGGAGCG ATCTCCCCGA GTACCCGCAG CTGTGGCCAG CCAGAAGACA 
GTCATCTTTC GTAATGTGCA GGACATCAGC CATTTCCACA GCAGCTTCTT GAAGGAGCTG 
CAGGGCTGTG GCACCGACGA TGATGTGGCC ATGTGCTTCA TCAAGAACCA GGAGGCCTTT 
GAGAAGTACC TCGAGTTCCT GGTGGGCCGC GTGCAAGCTG AATCAGTGGT TGTCAGCACC 
CCAGTCCAGG AGTTCTACAA GAAATATGCA GAAGAGACAC TGTCAGCCAA GGACCCCACA 
CAGCCACCCC CACCTCCTCT TCAGCACTAC CTGGAGCAGC CAGTGGAACG GGTGCAGAAA 
TACCAGGCCT TGCTGAAGGA GCTAATCCGC AACAAGGCCC GCAACCGGCA GAACTGCGCG 
CTGCTGGAGC AGGCCTATGC TGTGGTGTCT GCCCTGCCTC AGCGCGCCGA GAACAAGCTG 
CACGTTTCTC TCATGGAGAA CTACCCAGGA ACCCTGGAGG CCCTGGGAGA ACCTATCCGC 
CAGGGCCACT TCATAGTGTG GGAGGGGGCC CCAGGGGCCC GGATGCCTTG GAAGGGCCAC 
AACCGGCACG TCTTCCTCTT CCGAAACTAC CTGGTGATCT GCAAGCCCCG AAGAGACTCT 
CGAACCGACA CCTTCAGCTA TGTGTTCCGG AACATGATGA AGCTGAGTAG CATCGACCTG 
AATGACCAAG TAGAGGGGGA TGACCGCGCC TTTGAGGTGT GGCACGAACG GGAAGACTCT 
GTGCGCAAGT ACCTGCTGCA GGCACGGACC GTCATCATCA AAAACTCCTG GGTGAAGGAG 
ATCTGTGGCA TCCAGCAGCG CCTGGCCCAG CCTGTGTGGC GTCCCCCTGA GTTTGAAGAG 
GAACTAGCGG ACTGCACAGC CGAGCTGGGT GAAACGGTCA AGCTAGCATG CCGAGTGACG 
GGCACACCTA AGCCTATTGT CAGCTGGTAC AAAGATGGGA AGCCAGTGGA GGTGGACCCA 
CACCACATCC TCATTGAAGA CCCTGACGGC TCCTGCACCC TCATCTTGGA CAACCTTACT 
GGCATAGACT CTGGCCAGTA CATGTGTTTT GCGGCCAGTG CTGCTGGCAA CGCCAGCACC 
TTGGGGAAGA TTCTAGTACA AGTGCCCCCA CGGTTTGTGA ACAAGGTCCG GGCCACACCC 
TTTGTGGAGG GAGAGGATGC ACAGATCACC TGCACAGTGG AAGGAGCCCC GTACCCTCAG 
ATCAGGTGGT ACAAGGATGG TACCCTGCTA GCCCCGGGCA ACAGGTACCG GATGTTGAAT 
GAACCCCGCA GTGGTGTGCT GGTGCTGGTG ATCCAGGCGG CCAGCAAGGA GGACCTGGGA 
CACTATGAAT GTGAGTTGGT GAACCGGTTG GGCTCAACAC GTGGTGGTGG AGAACTATAC 
ATGCAGAGCC CTGCACTGCG TGCCCGGGAC CAGCACCACC GGGAACAGAT TGTGGCTGCC 
GTAGAAGTCA CTGAGCAGGA GACAAAAGTC CCCAAGAAAA CCGTCATCAT AGAGGAGACC 
ATCACCACCG TAGTGAAGAG TCCGCGTGGC CGACGACAGT CCCCCGGCAA GTCTCCCTCT 
CGTTCACCTT CCCGCCGCTC TGCCAGTCCA CGGAGACCAG GGCTGTTGGC CCCCGAGAGG 
CTGTATCCAC CAGGGACCAG CCCATCCCGG AGGCTTGAAG TAGAACAAGG CAGGAAAGCC 
CCGGTGCCTG CATTGTATGT GACAGAAGCA GAGGTCCACG CTCCAGCCTC GCAGTCCCAG 
CCCAAGTGGT TAGAGGTGGA GGAAACCATT GAAGTCCGGG TGAAGAAGAC GGGGTCACGG 
GGTGCATCTC CTGTCCGAGA GATGACCAGC CGTGGAGAAG GAATCCTCTT CACACTGCCT 
GGTGGGATCC CTGGTAGGGA CCCAAATGCC AACAACTCCA ACAACAAGAG TGTGTACCAG 
GAAGCCCGGA CCTGGGGTCC CGCTGTGGTC CATGTTGGTG AACCTTTCAT CTTCCAAGTG 
GACTCGGTGG GCAATGTGGA CTGGGTAGCT GCTAGCCCTG AGCCAGAGCA GGTCAGAGCC 
TCCCAGAAGG AAGAGAACAC TGAAAGGCAG GAAGGATGCA GTGATGGAGA CGAGAATACC 
TTCCTGATGG AAGAACCACA GGACACGGAT AGCCTTCAGG GCCGTGACCC CAAAATCCTC 
ACACACAATG GCCGGGTGCT GACATTGGCT GACCTGGAAG ATTATGTGCC CCAGGAAGGA 
GAGACTTTTG GCTGTGGGGA CTCCACCCCC AGCACCCCTG ATGAACCTCC CTGTGAAGTC 
TCCGTGCTCC AGAGAGAGAT CAGCGAGCCC ACGGTGGGGC AACCTGTCCT GCTCAATGTG 
GGGCGTCCTC CAGGCACCGG TGCCACTCCC AGCTTCTTCA GGCCAGGTTC CCAGGTCCAC 
AGCCCTGAGA GTGTCTCCTT CCTTTTGCGT GAGGCCTGGT CAGGTCCAGT GAGTGCCGCC 
CCTTGGACAA GCTCCTTCCA TACCCATGTC CAGAGTTCTG TAGATGGTAG CCATGGGAGC 
TTCAAGACAG AGGTCTCCAC CCAGACAGTC AGCTTTGGGG CCGTAGGAGA GACAGTCACT 
CTTCATATTG ACCCAGATGG TGGCGAGGCT CCAGGCCCCT CCCAGGGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_954603.3
CDS	1..22491
Translation	MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQEPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPSRFIEDLRSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRMSKAAPVEWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEVTEQETKVPKKTVIIEETITTVVKSPRGRRQSPGKSPSRSPSRRSASPRRPGLLAPERLYPPGTSPSRRLEVEQGRKAPVPALYVTEAEVHAPASQSQPKWLEVEETIEVRVKKTGSRGASPVREMTSRGEGILFTLPGGIPGRDPNANNSNNKSVYQEARTWGPAVVHVGEPFIFQVDSVGNVDWVAASPEPEQVRASQKEENTERQEGCSDGDENTFLMEEPQDTDSLQGRDPKILTHNGRVLTLADLEDYVPQEGETFGCGDSTPSTPDEPPCEVSVLQREISEPTVGQPVLLNVGRPPGTGATPSFFRPGSQVHSPESVSFLLREAWSGPVSAAPWTSSFHTHVQSSVDGSHGSFKTEVSTQTVSFGAVGETVTLHIDPDGGEAPGPSQG

Target ORF information:

RefSeq Version	NM_199152.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199152.3

ORF Insert Sequence:

ATGGACCACT CCTTCAGCGG AGCACCCCGC TTCCTGACGC GGCCAAAGGC CTTTGTGGTA 
TCTGTTGGCA AGGATGCCAC GCTGAGCTGC CAGATCGTGG GCAACCCCAC GCCACACGTG 
AGCTGGGAGA AGGACCGGCA GCCAGTAGAG GCAGGAGCGC GCTTCCGCCT GGCCCAGGAC 
GGGGATGTGT ACCGCCTCAC AATTCTCGAT CTGGCGCTAG GTGACAGCGG GCAGTATGTG 
TGTCGCGCGA GGAACGCCAT AGGGGAGGCC TTCGCCGCCG TCGGCCTGCG AGTGGACTCG 
GAGGGCACGT GTGCCGAGCA GGCGCCCCAC TTTCTGCTGC GGCCCACATC CATTCGCGTG 
CGCGAGGGCG CAGACGCCAC CTTCCGATGT CGCGTTGGAG GCTCACCACA ACCTGCTGTG 
AGCTGGTCCA AAGATGGGCG GCGCCTGGGC CCACCCGATG CCCCCCATGT GCGTGTGGAA 
GAACACGGGG AGTCGAGCGC GCTTCGCATC CGTTCGGCAA GGCCTCGCGA TGGTGGCACC 
TACGAAGTCC GAGCAGAAAA TCCGCTGGGC TCTGCCAGCG CTGCCGCCGC TCTGGTGGTG 
GACTCGGACG CCGAGGTTGC CGGACCACCC GGCACCTCCA CCGCCACGCT CCTGGCGCAC 
CTGCAGCAGC GGCGGGAGGC CATGCGCGCA GAGGGCATAC CCCCTTCTCC ACCCGGCGCT 
GGCACGCGCA CCTGCACGGT GACCGAAGGC AAACACGCGC GCCTCAGCTG TTTTGTGACC 
GGCGAGCCCA AGCCCGAGAC AGTGTGGAAG AAGGACGGGC AGCTGGTGAC CGAGGGCCGG 
CGACACGTAG TGTATGAGGA CGAGCAAGAG AACTTCGTCC TTAAGATTCT TTTCTGCAAG 
CAGTCCGACC GCGGCCTCTA CACCTGCACA GCGTCCAACC TCGTGGGCCA GACCTACAGC 
TCGGTGCTGG TGGTCGTGAG AGAGCCGACG GTGCCCTTCA AGAAGCGGCT GCAGGACCTG 
GAGGTACGAG AGAAAGAGTC TGCTACATTC CAGTGCGAGG TGGCTCAGCC AGCTACCGAG 
GCGGCGTGGT TCAAGGAGGA GACCCGGCTA TGGGCCAGCG CCAAGTACGA CATCGAGGAG 
GAGGGCACCG AGCGCCGGCT GACCGTGCGC AACGTCTCGG CAGACGACGA CGCTGTGTAC 
ATCTGCGAGA CCACAGAGGG CAGCCGCACG GTGGCAGAGC TCTCTGTTCA AGGAAACTTG 
ACCAGAAAGC TGCCTCGGAA GACAGCAGTG CGCACTGGAG ACACAGCCAT CTTTTGGGTG 
GAGCTGGCTG TCCCCGAAGG CCCTGTCCGG TGGCTACGGA ACCAGGAGGA GATGGTGGCA 
GGGGGTCGGG TTGCCATCAC TGCAGAAGGC ACGTGCCACA CACTGACCAT CTTCCAGTGC 
ACCTTGGAGG ACATGGGTGA GGTGGCCTTT GTGTCTGGTG GCTGCCGGAC GACCACCCAG 
TTCTGTGTAT CAGCGCCCAG GAGGCCACCC CTGTACCCTC CTGCTGACCC TGTTGTAAAG 
GCCAAGACAG AGAGTTCTGT GACCCTCAGC TGGTCCGCAC CACCCCATGG GGACCGCCCT 
GTCACTATTG ATGGCTATGT GTTGGAGAAG AGGAAGCTGG GTGCCTATGC CTGGAGCAGG 
TGTCACGAAG CTGGATGGCT GGCCACAACT GAGTTTACCA TCACTGGTGT GGCTGAGGAG 
GGGGATTTCC AGTTCCGAGT GTCAGCCATC AATCACTTTG GCCAGGGTCC TTACCTTGAA 
TTTCCAGGGA CCATGCACTT GGTCCCCATG CTGGCTGTAA AGACACCTCT GAAGGCGGTG 
GAGGCAGTGG AGGGTGGTGA GGTCACTTTC TCCGTGGACC TCACGGTGGC CTCTTCGGGC 
GAATGGTTCC TGGATGGGGA GGCCTTGAAA GCGAGCAGTA TATACGTGAT CCGTTGTGAC 
CGCACCCGGC ATATGCTCAC CATCAGAGAG GTGCCCGCCA GATTGCATGG GGCACAGCTG 
AAGTTTGTGG CTAATGGCAT TGAAACTAGC ATCCAAATGG TGGTCCGAGC GGCTCTGGGG 
CTGCCCAGCA GTAAGCTTCC TGCTGCGGCT GCCCGGGAGG TGCTGGCCCA GTTGCACGAG 
GAGGCACAGC TGCTGGCTGA GCTGTCGGAC CAGGCTGCTG CTGTGACTTG GCTGAAGGAT 
GGTCGTGAGC TGTCCCTAGG GCCCAAGTAT GAGATGCAGG TGTCAGCTGG GAGGCGAGCA 
CTGCTGGTGC GGGACGTGGC ACAGGATGAC GCTGGCCTCT ATGAGTGTGT CAGTCGTGGG 
AGCCGCACTG CCTACCAGCT GTTGGTGCAA GAACCCAAGC TGGTGTTTGC CAAGGGGCAG 
CAGGCACACA GCGAGGTGAA GGCAGAGGCG GGGAACAGCG CCACCCTGAG CTGCGAGGTG 
ACCCAGGCCC AGACTGAGGT GACATGGTTC AAGGATGGGA AGAAGCTGAG CTCCAGCTCG 
AAGGTGCGCA TGGAGGCCTC GGGCTGCTCC AGGAGGCTGG TGGTGCAGCA GGCGGGCAAG 
GCGGATGCTG GGGAGTACAG CTGCGAGGCC GGGGGACAGA AGCTCTCCTT CCGCCTGGAC 
GTGGCAGAAC CCAAGCTGGT ATTTGCCAAG GGGCAGCAGG CACACAGTGA GGTGAAGGCA 
GAGGCGGGGG CCAGCGCCAC ACTGAGCTGC GAGGTGGCCC AGGCCCAGAC TGAGGTGACA 
TGGTTCAAGG ACGGGAAGAA GCTGAGCTCC AGCTCGAAGG TGCGCATGGA GGCCTCGGGC 
TGCTCCAGGA GGCTGGTGGT GCAGCAGGCG GGCAAGGCGG ATGCTGGGGA GTACAGCTGC 
GAGGCCGGGG GACAGAAGCT CTCCTTCCGC CTGGACGTGG CAGAGCCCAA GATGGTGTTT 
GCCAAGGAGC AGCAGGCACG CAGCGAGGTG AAGGCCGAGG CGGGGGCCAG CGCCACACTG 
AGCTGCGAGG TGGCCCAGGC TCAGACTGAG GTGACATGGT TCAAGGACGG GAAGAAGCTG 
AGCTCCAGCT CGAAGGTGCG CATGGAGGCC TCGGGCTGCT CCAGGAGGCT GGTGGTGCAG 
CAGGCGGGCA AGGCAGATGC TGGGGAGTAC AGCTGCGAGG CCGGGGGACA GAAGCTCTCC 
TTCCGCCTGG ACGTCACAGA GCCCAAGCTG GTGTTTGCCA AGGAGCAGCA GGCACGCAGT 
GAGGTGAAGG CAGAGGTGGG GAACAGTGCC ACACTGAGCT GCGAGGTGGC CCAGGCCCAG 
ACTGAGGTGA CATGGTTCAA GGACGGGAAG AAGCTGAGCT CCAGCTCGAA GGTGCGCATG 
GAGGCCTCGG GCTGCTCCAG GAGGCTGGTG GTGCAGCAGG CGGGCAAGGC GGATGCTGGG 
GAGTACAGCT GCGAGGCCGG GGGGCAGAAA CTCTCCTTCC GCCTGGACGT GGCAGAACCC 
AAGCTGGTGT TTGCCAAGGA GCAGCAGGCA CGAAGTGAGG TGAAGGCAGA GGCAGGGAAC 
AGTGCCACAC TGAGCTGTGA GGTGGCCCAG GCACAGACTG AGGTGACATG GTTCAAGGAC 
GGGAAGAAGC TGAGCTCCAG CTCAAAGGTG CGCATGGAGG CCTCGGGCTG CTCCAGGAGG 
CTGGTGGTGC AGCAGGCGGG CAAGGCGGAT GCTGGGGAGT ACAGCTGCGA GGCCGGGGGA 
CAGAAGCTCT CATTCCATCT GGACGTCACA GAACCCAAGC TGGTGTTTGC CAAGGAGCAG 
CAGGCACACA GTGAGGTGAA GGCAGAGGCG GGGGCCAGTG CCACCCTGAG CTGCGAGGTG 
GCCCAGGCCC AGACTGAGGT GACATGGTTC AAGGACGGAA AGAAGCTGAG CTCCAGCTCA 
AAGGTGCGCA TGGAGGCCTC GGGCTGCTCC AGGAGGCTGG TGGTGCAGCA GGCGGGCAAG 
GCGGATGCTG GGGAGTACAG CTGCGAGGCC GAGGGACAGA AGCTCTCCTT CCGCCTGGAC 
GTGGCAGAGC CCAAGCTGGT GTTTGCCAAG GAGCAGCAGG CACGCAGCGA GGTGAAGGCA 
GAGGCTGGGG CCAGTGCCAC ACTGAGCTGT GAGGTGGCCC AGGCCCAGAC TGAGGTGACA 
TGGTTCAAGG ACGGGAAGAA GCTGAGCTCC AGCTCGAAGG TGCGAGTGGA GGCCTCGGGC 
TGCTCCAGGA GGCTGGTGGT GCAGCAGGCG GGCAAGGCGG ATGCTGGGGA GTACAGCTGC 
GAGGCCGGGG GCCAGAAGCT CTCCTTCCGC CTGGACGTCG CAGAGCCCAA GCTGGTGTTT 
GCCAAGGAAC AGCAGGCAAA CAGCGAGGTG AAGGCCGAGG CGGGGGCCAG CGCCACACTG 
AGCTGCGAGG TGGCCCAGGC CCAGACTGAG GTGACATGGT TCAAGGACGG GAAGAAGCTG 
AGCTCCAGCT CGAAGGTGCG CGTGGAGGCC TCGGGCTGCT CCAGGAGGCT GGTGGTGCAG 
CAGGCGGGCA AGGCGGATGC TGGGGAGTAC AGCTGCGAGG CCGGGGGGCA GAAGCTTTCC 
TTCCGCCTGG ACGTGGCAGA GCCCAAGCTG GCGTTTGCCA AGGAGCAGCA GGCACACAGC 
GAAGTGAAGG CAGAGGCGGG GGCCAGCGCC ACACTGAGCT GCGAGGTGGC CCAGGCCCAG 
ACTGAGGTGA CATGGTTCAA GGATGGGAAG AAGCTGAGCT CCAGCTCGAA GGTGCGCGTG 
GAGGCCTCGG GCTGCTCCAG GAGGCTGGTG GTGCAGCAGG CGGGCAAGGC GGATGCTGGG 
GAGTACAGCT GCGAGGCCGG GGGACAGAAG CTCTCATTCC GCCTGGACGT GGCAGAGCCC 
AAGCTGGCGT TTGCCAAGGA GCAGCAGGCA CACAGCGAGG TGAAGGCAGA GGCGGGGGCC 
AGCGCCACAC TGAGCTGTGA GGTGGCCCAG GCCCAGACTG AGGTGACATG GTTCAAGGAC 
GGGAAGAAGC TGAGCTCCAG CTCGAAGGTG CGCGTGGAGG CCTCGGGCTG CTCCAGGAGG 
CTGGTGGTGC AGCAGGCGGG CAAGGCGGAT GCTGGGGAGT ACAGCTGCGA GGCCGGGGGT 
CAGAAGCTCT CCTTCCGCCT GGACGTGGCA GAGCCTAAGC TGGCGTTTGC CAAGGAACAG 
CAGGCACACA GCGAGGTGAA GGCAGAGGCG GGGGCCAGTG CCACACTGAG CTGCGAGGTG 
GCCCAGGCCC AGACTGAGGT GACATGGTTC AAGGACGGGA AGAAGCTGAG CTCCAGCTCG 
AAGGTGCGCG TGGAGGCCTC GGGCTGCTCC AGGAGGCTGG TGGTGCAGCA GGCGGGCAAG 
GCGGATGCTG GGGAGTACAG CTGCGAGGCC GGGGGACAGA AGCTCTTCTT CCGCCTGGAT 
GTGGCAGAGC CCAAGCTGAT GTTTGCCAAG GAGCAGCAGG CACACAGCGA GGTGAAGGCA 
GAGGCTGGGG CCAGCGCCAC ACTGAGCTGC GAGGTGGCCC AGGCCCAGAC TGAGGTGACA 
TGGTTCAAGG ACGGGAAGAA GCTGAGCTCC AGCTCGAAGG TGCGCGTGGA GGCCTCGGGC 
TGCTCCAGGA GGCTGGTGGT GCAGCAGGCG GGCAAGGCGG ATGCTGGGGA GTACAGCTGC 
GAGGCCGGGG GGCAGAAGCT CTCCTTCCGC CTGGATGTGG CAGAGCCCAA GCTGGTGTTT 
GCCAAGGAGC AGCAGGCACA CAGTGAGGTG AAGGCCGAGG CGGGGGCCAG CGCCACCCTG 
AGCTGCGAGG TGGCCCAGGC CCAGACTGAG GTGACATGGT TCAAGGACGG GAAGAAGCTG 
AGCTCCAGCT CGAAGGTGCG CGTGGAGGCC TCGGGCTGCT CCAGGAGGCT GGTGGTGCAG 
CAGGTGGGCA AGGCGGATGC TGGGGAGTAC AGCTGCGAGG CCAGGGGACA GAAGCTCTCC 
TTCCGCCTGG ACGTGGCAGA CACCAGGCTG ATGTTTGCCA AGGAGCAGCA GGCACGCACC 
GAGGTGAAGG CTGAGGCGGG GAACAGTGCC ACCCTGAGCT GCGAGGTGGC CCAGGCCCAG 
ACTGAGGTGA CATGGTTCAA GGACGGGAAG AAGCTGAGCT CCAGCTCGAA GGTGCGCGTG 
GAGGCCTCGG GCTGCTCCAG GAGGCTGGTG GTGCAGCAGG CGGGCAAGGC GGATGCTGGG 
GAGTACAGCT GCGAGGCCGG GGGTCAGAAG CTCTCCTTCC GCCTGGACGT GGCAGAGGCC 
GAATCCCAGA TTCCGGAGAG ACCCAGCCGC AGGGAACCTC TGGTTGTCAA GGAACATGAG 
ACCATTATCC TGACTGCCAC AATAGCTGCA CCCTCTGTGG CTGCTGTGAC CTGGCTCAAA 
GATGGAGTGG AGATCCGCCG CAGTAAGCGG CATGAGGCCA CCAGTCTGGG TGATACCCAT 
ACCCTGACCG TGAGAGGCGC ACAGGTCCTG GACAGTGCCA TCTACAGCTG CCGTGTTGGC 
AAGGAAGGTC AGGACTTCCC GGTGCAGGTA GAAGAGGTGG CCGCCAAGTT CTCCAAACCC 
CTGGAGCCCG TCGAAGGGGA GCTGGGTGGC ACCGTGATGC TGGTTTGTGA GCTGAGCCCG 
GAGCAGGCTG AGGTTGTGTG GCGCTGTGGG AACACACAGC TGCGGCCAGG CAAGCGCTTC 
CAGATGACAT CAGAGGGGCC TAGGCGCACG CTGACCGTGT CTGGCCTTCG AGAGGATGAC 
GCAGAGGAGT ATGTGTGTGA GAGCCGGGAT GACCGCACCA GCGCACGGCT CACTGTTAAA 
GTTCCCCGAG TGGTCAAGTT TACGTCTGGA TTGAGTGCCA TGGTCGCAGA GGAGGGCCAA 
GAGGCCACCT TTCAGTGTGT CGTGTCCCCC AGCGATGCAG GGGTCACATG GTACAAGGAC 
GGGATGCAGC TGCAGCCTAG CGAGAAGTTT GTTATGGTAG AGAGTGGGGC CAGCCGCAGC 
TTGACTATCT TGGGCCTGAC CCTGGAGGAT GCCGGTCAAG TCACAGTGGA GGCTGAGGGG 
GCTTCATCTT CTGCTGCCCT CCGGGTCCGA GAGGCACCGG TCCTCTTCAA AAAGAAGCTG 
GAGCCACAGA CAGTGGAGGA GAGGACCTCT GTGACATTGG AGGTGGAGCT GACGCGGCCC 
TGGCCCGAGG TGAAGTGGAC ACGGAATGCT GCCGTCCTGA CACCCAGCGA GAACGTGGAG 
ATCCGCGCTG AGGGTGCTCG GCACTGTCTG GTGCTGCGCA GCGTGGGCTT TGCTGACCGC 
GGCTTCTTTG GCTGTGAGAC ACCAGATGAT AAGACTCAGG CCAAGCTCAA TGTAGAAATG 
CGGCAGGTCC GGCTGGTTCG CGGTCTGCAG GAGGTGGAGG CTAAGGAACA GGGCACGGCC 
TCGATGGATG TGGAGCTGTC CCATGCCGAG GTGGAGGGCA GCTGGACCCG AGATGGCCTG 
CGACTTCAGC CTGGACCCAA ATGCCACCTG GCCGTACAAG GCCCTGTCCA CATCCTCACA 
CTCTCGGCGC TGCAGCCACA GGACAGTGGG CTGGTGGCCT TCAGGGCCGA GGGCGTGCAC 
ACGTCTGCGA GGCTCATAGT CACTGAGTTG CCCGTGAGCT TCACCAGAGT ACTACAGGAT 
GTGGTGGCCA CGCAGAAGGA GAAGGTCACC CTGGAGTGTG AGCTGTCGAG GCCTGTGGAT 
GTGCGCTGGC TGAAGGATGG TGTGGAGCTG CGGGCAGGCA AGGCCATAGG CATAGTGGCC 
CAGGGAACCT GCAGGAGTCT CGTTATCTAC CGCTGTGAGA CTGGGGACCA GGGTGTCTAT 
GTATGTGATG CTCTTGATGC TCAGACCTCT GCCTCTCTGA GGGTGCAAGG GAGGACATAC 
ACGCTTATCT TCCGGAGGGT ACTGGCAGAG GATGCAGGGG AGGTCAAGTT TGTAGCTGAG 
AACGCAGAAT CAAGAGCTCA CCTCCGAGTG AAAGAACTGC CCGTGACCCT CCTGCGCCCA 
CTGAGGGACA AGATTGCCAT GGAAAAACAC CGTGGAGTGC TGGAGTGCCA GGTGTCCCGG 
GCTAGTGCCC AGGTGCGGTG GTTCAAGGGC GGAGTCGAGC TGCAGTCTGG GCCCAAGTAC 
GAGGTGGTCA GTGACGGCCT TTACCGCAAG CTGGTCATTA ATGACGTGCA GCCTGAGGAT 
GAAGATACGT ACACCTGTGA CGCTGGCAAC GTCAAGACCA GTGCCCAGTT CTTTGTGGAA 
GAGCAATCCA TCACTATTGT GCGGGGACTG AAGGACATGA CAGTGATGGA GCCTGCCCCT 
GCCTGGTTTG AATGTGAGAC ATCCATCCCT TCCGTGAGGC CACCCAAGTG GCTCCTTGGT 
AAGACTGTGC TCCAGGCAGG GGGGAACGTG GGACTGGAGC AAGACGGCAC CGTGCACCGG 
CTGACACTGC ACAAGACCTG CTCTACCATG ACCGGGCCTG TGCACTTCAC TATCGGCAAG 
TCCCGCTCCT CTGCCCAGCT GGTTGTCTCA GACATTCCTG TGGTACTGAC ACGGCCTCTG 
GAGCCCAAAG CAGGGCGTGA ACTGCAGTCA GTAGTCCTGT CCTGTGACTT CAGGCCAGCC 
CCCAAGGCTG TGCAGTGGTA CAAGGATGAC ACACCCCTGT CCCCGTCAGA AAAGTTCAAG 
ATGGCGCTGG AGGGCCAGAT GGCAGAGCTG CGCATACTCC GGCTCACGCC AGCTGATGCT 
GGGGTCTACC GGTGCCAGGC GGGTAGCGCC CAGAGCAGTG CTGAGGTTAC TGTGGAAGCT 
CGGGAGGTGA CAGTGATTCA GCCACTGCAG GATGCAGAAG CCATGGAGGA AGGCCGGGTC 
TGCTTCTCCT GCGAGCTGTC CCATAAGGAT GAAGATATCG AATGGTCACT CAATGGTACA 
CCCCTGTACA ATGACAGCTT CCATGAGATC AGCCATGAGG GCTGTCTCCA CACCCTGGTG 
CTGAAGAGTG TCCGGCAGGC TGACACAGGC ACCGTGTGCG CCACCTCCCC CAAGGTGTCC 
GTTTCCGCCC GGCTGGTGGT TAAAGGCAAG CCAGTGGTGT TCCTGAAAGC ACTGGATGAC 
GTATCTGCAG AAGAGCGTGG CACGCTGACC CTGCAATGCG AGGTCTCCGA CCCCGAGGCA 
CGCGTGGTTT GGCGCAAAGA TGGTGTGGAG CTTGGTCCCA GCGACAAGTA TGATTTCCTA 
CATAAGGCAG GTGCCCGGGG CCTTACGGTC CATGACCTGA GCCATGAGGA TGCTGGACTG 
TACACCTGCC AGGTGGGCAG TAAGGAGACC CAGTCCAAGG TCAGCGTACA TGATCTTCAC 
GTGGGCATCA CCAAGAGGTT AAAGACAGTG GAGGTGCTGG AGGGAGAGAG CTGCAGCTTT 
GAGTGTGTCC TTTCCCACGA GAGTCCCAGT GACCCAGCAG TGTGGACGGT CGGTGGGAAG 
ACAGTGGGTG GTTCTGGCCA CTTTCACGCC GTTCGGCAGG GCCGCAAATA CACCCTGACA 
GTCAAAGATG CTGCACTCAG TGATGCAGGA GAGGTGGTCT TCTCGGTGCT GGGCCTCACT 
TCCAAGGCCT CGCTCATCAT CAGAGAGAGG CCAGTGGACA TCACCAAGCC CCTGGAGGAC 
CAGCGGACGA CGCTTGGGGA AGATGTAATG CTAAGCTGTG AGCTGTCCAG GGCAGGCACC 
TCTGTGCGCT GGCTGAAAGA CGGGAAGGCC ATCAGGAAGA GCCAGAAGTA TGACCTGCTC 
AGTGAAGGCA CGCGGGCTGT GTTGGTTGTC CGCAAGGCCT CACTCAAGGA TTCAGGGGAA 
TACACCTGCG AGACAGAAGC TTCGAAAAGC ACTGCCAAGC TCTGTGTGGA AGAAAAGGCA 
AACCGGTTCA CGGAGGAGCT GGCTGACCTG CAGGTGGAAG AGAAGGGCAG AGCTGTGTTC 
ACATGCAAGA CAGAGCACCC AGCATCTGTC GTGACCTGGC GCAAAGGCCT CCTGGAGCTG 
CGCGCCTCAG GGAAGCATGT CCCCAGTCAG GAAGGCTTGA CCCTGAAGCT CACCATCAAC 
GCCCTGGAGA GGACAGACAG TGACACTTAC ACCTGTGACA TCGGCCAAGC CCGGACCCAG 
GCACGGCTCC TCGTCCACGG CCAGAAAGTG CGCGTTATTG AGGACCTAGA GGACACTGCT 
GTCCAGGAGG GCTCCTCTGC TAAGTTTTGC TGCCGCATCG CTCCTGCTGA CTACGGCCCC 
GTGCACTGGT TCCTGGATAA GACCCCCTTG CACAGCAATG AGCTGAATGA GATCACTGTC 
CAGCCTGGAG GCTATCACGT GCTCACCCTG CGGCAGCTGG CACTCAAGGA CTCAGGCACT 
GTCTACTTTG AGGCGGGTGA CCAGCGAACC TCAGCTGCCC TGCGGGTGAC TGAGAAGCCG 
AGCATCTTCT CTCGGCCACT CACAGACGTC ACAGTCACAG AAGGCGAGGA CCTGACTCTG 
GTCTGTGAAA CCACCACTGT GGATAGCTCT GTGCGCTGGA CCAAAGATGG GAAGACACTG 
AGGCCGTCTG CACGATGCCA GCTGAGCCAT GAAGGCTGTC AGGCCCAGCT GCTCATCACT 
GCCACCACCC CACAAGATGG TGGGCGGTAC AAATGTGAGA TTGGTGGAGC CTCCAGCAGC 
TCCATTGTCA GGGTCCATGC TCTGCCAGTG CGGTTCAGGG AGTCCCTGAA GGACGTGGAG 
GTACCAGAGG GCAAGGCCGC CACACTGCGC TGTGTGCTGT CATCCGTGGC TGCACCTGTG 
GAGTGGCGTC ATGGAGATGA TGTCCTGAAA TCCAGCAACA AGTATAGCCT GCGCCAAGAG 
GGTGCTGTGC TGGAATTGGT CATCCGAGAC CTGCAGCCCC AGGACAGTGG GCAATACTCA 
TGCTCCTTTG GGGACCAGAC AACTTCAGCC ACACTCACAG TGAAAACCTC TTCTGCCCAG 
TTCGTAGGGA AACTGAGAAA CAAGGAGGCC ACAGAAGGGA CCACGGTCAC ACTTCGGTGT 
GAGCTGACCA AAGAGGCCCC CGTGGAGTGG AAGAAGGGAA CAGAGACCCT GAGAAATGGG 
GACAAATACA GTCTGAAGCA GGATGGAGCT GTGTGTGAGC TGCAGATCTG TAGTCTGCTG 
GTGGCAGATG CAGGGGAGTA CTCGTGTGTG TGTGGGCAGG AGAAGACTTC AGCCACGCTG 
ACTGTCAAGG CTCTGCTTGT CCACTTTGTC AGAAGGCTCA GGAGCAAGGA GGCCACAGAA 
GGAGACACGA CCACACTGCA GTGTGAACTG AGCAAGGCTG CCCCCGTGGA GTGGAGGAAG 
GGAACAGAGA CCCTGAGAGA TGGGGACAGA TACAGCCTGA AGCAGGATGG GGCTGTGTGT 
GAGCTGCAAA TCCGCAGCCT GACCATAGCA GATGCTGGCG AGTACTTGTG CACGTGTGGA 
CAGGAAAAGA CCTCAGCCAC GCTGACCGTC AGGGCCCTTC CAGCTAAGTT CAAAGACAGT 
CTGAAGAATG AAGAGGCTAC AGAAGGCACC ACAGCTACAC TGAGCTGTGA ACTGAGCAAG 
GCAGCTCCGG TGACATGGAA GAAAGGACCG AAGACCTTGC AAAGTGGAGA CAAATATGTC 
CTGAGGCAGG ATGGAGCTGT GTGTGGACTA CAGATCCATG GCCTGACCAT GGCTGATGCT 
GGGGAGTACT CGTGTGTGTG TGGGCAGGAG AAGACGTCAG CCACGCTGAC TGTCAGGGGC 
TTGCCTGCCA AATTTATAGA AGATCTGAGA AGCCAAGAAG CCACAGAAGG GGCCACAGCA 
ATCTTAAGAT GTGAGCTGAG CAAGGCTGCT CCTGTGGAGT GGAGGAAAGG GTCTGAGACC 
CTGAAAGATG GGGACAGATA CACCCTGAGG CAGGATGGGG CCGTATGTGA GCTGCAGATC 
CGTGGCCTGG CTGTGGTGGA TACTGGGACA TACTCGTCCC TGCCCACCAA GTTCACAGAG 
GGTCTGAGGA ATGAAGAGGC CACGGAAGGC ACCATGGCCA CTCTGAGGTG CCAGATGAGC 
AAGGCTGCCC CTGTGGAGTG GAGGAAGGGG TCAGAGACCC TGAGAGATGG GGACAGATAC 
AGCCTGAGGC AGGATGGGGC CATGTGTGAG CTGCAGATCC GTGGCCTGAC CATAGAAGAT 
TCTGGGGAGT ACACATGTGT GTGTGGGCAG GAGAAGACGT CAGCCACACT GAGTGTCAAG 
GCCCTGCCCT CCAGATTCAT AGAAGATTTG AGAAGTCAAG AGGCCACAGA AGGCACCATG 
GCCACTCTGA GGTGCCAGAT GAGCAAGACT GCCCCTGTGG AGTGGAAGAA GGGGTCTGAG 
ACCCTGAGAG ATGGGGGCAG ATACAGCCTG AGGCAGGATG GGCCTGTGTG TGAGCTGCAG 
ATCTGTGACC TGGCTGTCGA AGACGCTGGG GAGTACTCAT GTGTGTGTGG GCAGGAGAAG 
ACCTCAGCCA CACTGAGTAT CAAGGCTCTG CCCCCCAGAT TCATAGAAGA CTTGAGAAGC 
CAAGAGGCCA CAGAAGGCAC CATGGCCACT CTGAGGTGCC AGATGAGCAA GGCAGCCCCT 
GTGGAGTGGA GGAAGGGGTC TGAAACCCTG GGAGATGGGG GCAGATACAG CCTGAGGCAG 
AATGGTGCTG TGTGTGAGCT GCAGATCCAT GACCTGGCTG TGGAAGACAC TGGGGAGTAC 
TCATGTGTGT GTGGGCAGGA GAAGACCTCA GCCACACTGA ATGTCAAGGC CCTGCCCCCC 
AGATTCATAG AAGACTTGAG AAGCCAAGAG GCCACAGAAG GCACCATGGC CACTCTGAGG 
TGCCAGATGA GCAAGGCAGC CCCTGTGGAG TGGAGGAAGG GGTCTGAGAC CCTGAGAGAT 
GGGGGCAGAT ACAGCCTGAG GCAGGATGGG GCTGTGTGTG AGCTGCAGAT CCATGACCTG 
GATGTGGAAG ATGCTGGCCA GTACTCGTGC GTGTGTGGGC AGGAGAAGAC CTCAGCCGTG 
CTGACTGTAG ATGCACTGCC CCCCAAGTTT ACAGAGGGTC TGAAGAAGGA AGAGGCCACA 
GAAGGGACCA TGGTAACACT GAGGTGCCAG ATGAGCAAAG AAGCCACGGT GGAGTGGAGG 
AAGGGAGCAA AGACCCTCAG CGATGGGGGC AGATACAGCC TGAGGCAGGA TGGGGCCATG 
TGTGAGCTGC AGATCTGTGG CCTGGCTGTG GAAGACGCTG GGGAATACTC ATGTGTGTGT 
GGGCAGGAGA AGACCTCAGC CACACTGAGT GTCAAGGCCC TGCCCCCCAG ATTCATAGAA 
GACTTGAGAA GCCAAGAGGC CACAGAAGGC ACCATGGCCA CTCTGAGGTG CCAGATGAGC 
AAGGCTGCCC CTGTGGAGTG GAGGAAGGGG TCTGAGACCC TGAGAGATGG GGACAGATAC 
AGCCTGAGGC AGGATGGGGC TGTGTGTGAG CTGCAGATCC GTGACCTGGC TGTGGAAGAT 
GCTGGCGAGT ACTTGTGCGT GTGTGGGCAG GAGAAGACCT CAGCCACACT AAGTGTCAAG 
GCCCTGCCCC CCAGATTCAT AGAAGACTTG AGAAGCCAAG AGGCCACAGA AGGCACCATG 
GCCACTCTGA GGTGCCAGAT GAGCAAGGCT GCCCCTGTGG AGTGGAGGAA GGGATCCAAG 
ACCCTGAGAG ATGGGGACAG ATACAGCCTG AGGCAGGATG GGGCCATGTG TGAGCTGCAG 
ATCTGTGACC TGGCTGTGGA AGACACTGGG GACTACTCAT GTGTGTGTGG GCAGGAGAAG 
ACCTCAGCCA CACTGAGTGT CAAGGCCCTG CCCCCTAGAT TCATAGAAGA TTTGAGAAGC 
CAAGAGGCCA GGGAAGGTAC TGTGGCCACT CTGAGGTGCC GGATGAGCAA GGCTGCCCCA 
GTGGAGTGGA GGAAGGGGTC AGAAACCCTG AAAGATGGGG ACAGATACAG CCTGAGGCAG 
GAGGGGAACC TGTGTGAGCT GCAGATCCGT GACCTGGCTG TCGAAGACAC TGAGGAGTAC 
TCATGTGTGT GTGGGCAGGA GAAGACCTCA GCCACACTGA GTGTCAAGGC CTTGCCAGCC 
AAATTCATAG AAGACTTGAG AAGCCAAGAG GCCCCGGAAA GTTCAACAGT CACATTGCGG 
TGTAAGCTAA GCAAGAAGGC CTCTGTGGTG TGGAAGAAAG GGTCTGAGAC CCTAAGAAAT 
GGGGCCAGAT ACAGCCTGAG GCAAGATGGG GCTGTGTGTG AGCTGGAGAT CCGAGACCTG 
ACTGTGGAAG ATACTGGAGA GTACTCGTGC ACATGTGGGC AGGAGAGGAC CTCAGCCACA 
CTGAGCATTA TGGCTCCACA GGTGGTATTC CAGCAGCCAC TGCAGAATCT GCAAGCAGAA 
GAAGGCTCCA TGGCCAGCCT GCGGTGTGAG TTGTCAGTCC CCAACGCTGC CATGGTCTGG 
AGCAAGGGTG GTCTGGAGCT GCAGGGTGAC ACGCGCCGAG AGGCACGGCA GCAGGGGTGT 
GTGGCAGAGC TGTTGCTTAG GGACCTGCGT CGCGAGGATG CGGGCGAGTA CAGTTGCACC 
TGTGGCTCTC AGACCACAAG CGCCACGCTC ATGGTCACAG CTGCTCCTGT GCGGTTCCTC 
CGGGAACTGC AGGCCCAGGA CGTAGATGAG GGGGCCACCG CACGCCTGCG CTGTGAGCTG 
AGCCGGGAGG CTGTGAGCGT GGAGTGGCGC AAGGGCTCCT TGCAACTTTT TCCTTGTGCT 
AAGTATCAGA TGGTGCAGGA GGGCACAACT GCGGAGCTGC TGGTCCATGG GGTGGAGCAG 
GAGGATGCAG GCGAATACAC CTGCGATGCA GGCCACACGC AGAGCATTGC CAGGCTCTCT 
GTCCGAGCCC CCAAGCCCAA GTTCAAGACC GACCTGCAAA GCACAGAGCA GGAAGCAGGT 
GGCACGGCAC GGCTGTGTTG TCAACTGAGC GAAGCTGAGC CAGGGACTCC AGTGCAGTGG 
CTCAAGGAGG GGGTGGAGCT GCACGTCGGC TCCAAGTATG AGATGCGGCG CCAAGGGGCT 
GTGTGCGAGC TGCTGATCCA TGGGCTGGAG GCCAAGGACA CTGGAGAATA TGCCTGCCTG 
GTGGGTGGCC AGAAGACCTT GGCCTCCCTC AGAGTCAAAG AGCCTGAGGT GACCATCGTG 
CGGGGACTCG TGGACATGGA GGTGCAGGCC GATGAGGATG TGGAGTTCAC TTGCAAGGTG 
TCACAGGCAG GAGCCACAGA CGTGCAGTGG CACCTCCAAG GTCTGCCACT GCAGAGCAAT 
GAAGTGACAG AGGTGGCTGT CCTTGCGGAC GGCTGTACCC ATGTGCTCCA GTTAAAGGGT 
GTGACACTGG AGGATGCTGG TACTGTCTCC TTCCACGTGG GCGGCCTTTC ATCTTCTGCT 
CAGCTCACAG TCCGAGTCCC TGAGGTGACC GTTCTGGAGC CCCTGAAGGA TGTGCAGCTC 
AGCGAGGGCC AGGATGCCCA CTTCCGGTGC CGACTGTCCA GGGCCTCGGG CCAGGAGGCT 
CGCTGGGCTT TGGGAGGGGT TCCCTTGCAG TGCAACGAGA TGAACGACAT CACTGTGGAG 
CAGGGCACAC TCTACCTGCT CACTCTGCAC AAGGTGACCC TGGAGGATGC TGGGACCATC 
ACTCTCCAAG TGGGCTCATG CTCCTCAGAG GCCCAGCTGA AGGTCACAGC CAAGAACACG 
GTGTTGCGTG GCCTGGAGAA CGTGGATGCA CTGGAGGGCG GTGAGGCTCT GTTCGAGTGC 
CAGCTGTCCC AGCCTGAAGT GGCCGCCCAC ACCTGGCTGC TGGACGACGA GCCTGTGCAC 
ACGTCGGAGA AGGTGGAGGT GGTCTACTTT GAGAACGGAC TGCGGCACCT GCTTCTACTC 
AAAAACCTGA AGCCACAGGA CAGCTGCCGA GTGACCTTCC TGGCAGGGGA TGTGGTCACG 
TCCGCATTCC TCACTGTGAG AGGCTGGCGC TTGGAGGTCC TAGAGCCCCC ACATGATGCA 
TCTGTGAAAG CTGGTATGCA GGTCCGCTTC ACATGCATAC TAAGTGAGGC GGTGCCTGTG 
GGTGAGGCTA CTTGGTACAT CAACGGGGCT GCCATCCAAC CTGATGACAC TGACTGGACA 
GTCACCACAG ATGGCAGCCA CCATGCCCTG ACGCTGAGCA ATGCCCAGCC CCAACACGCA 
GGAGAGGTCA CATTTGCAGC ACGGGATGCT GTGGCCTCTG CACGCCTCTC TGTGTTGGCT 
CTTCCTGACC CCCCTGAAGA TGCTGAAGTG GTGGGGCGTA GTGACCATTC TGTGACCCTA 
TCCTGGGTGG CTCCCATGAG TGATGGAGGT GGGGGTCTAT GTGGTTATCG TGTGGAGATG 
AAGGAGGCAT CCACAGGCCA GTGGCAGTTG TGCCATGACT TGGTACCTGG TCCAGAGTGC 
GTGGTGGACG ACCTGGTCCC CGGGAAGACC TACCGCTTCC GAGTGGCAGC TGTGGGTCCA 
GCAGGTGCTG GGGAGCCTGT ACACTTGCCC CAGATGGTCA AGATAGCCCC AGCCCCGGCC 
CCGGCCCCGG CCCCTGCCCC AGCCCCTGCC CCAGAAACAC GGCAGGCAGT AGTTGGTGAA 
GACATCTGTC TGGAGTTGGA AGTGGCAGCT GATGGTGGCG AGGTCGTCTG GCACAAGGGA 
ACAGAGCGCA TCCAGCCCGG AGGGCACTTT GAGGTCCTCT CTCGGGGTCA GCGGCAGATG 
CTGGTGATCA AGGGCTTTAG GACCGAAGAC CAAGGGGAGT ACCGCTGTGG TCCCATTCAG 
GGTCTGCCCT CCTCAGGAGC TGCCACGTTC AATGTGGTCA TGACCTCAGG CTCTGGGGAT 
GAGGTCCCGG CACAGCCTAG CCTGCCTCCC GAGGCAGCCC AGGAGGGTGA CCTGCATCTG 
CTTTGGGAGG CCCTTGCCCG GAAGCGCCGC ATGAGTCGGG AGCCCACGCT GGACTCCATC 
AGTGAGCTGC CTGAGGAAGA CAGCCGTGTG CAGCATCTGC GGCAGGAGGC AGAAGAGACA 
GCTCCCGACC TCTCTGAAGG CTACTCTACA GCGGATGAGC TAGCACGCAC AGGAGAGGCC 
GACCTCTCAC ACACCAGCTC TGACGATGAG TCTCGGGCTG GCACCCCTTC CCTAGTTACC 
TACCTCAAGA AGGCCGGGGG TCCTGGGATC TCACCCTTGG CCAGCAAGCA TGAGGCCCAG 
GTGACCACGT CTGTGAAGCC ACAAAAGCAG CAGGAGCCAG TCGTGCCCAC GTGCCCACCG 
CCGGGAGACT TGAGTGCAGC AGATTTGATG GATCCATCCC TGGACAAGGC TGCTGTGAAG 
ATTCAGGCTG CCTTTAAGGG TTACAAAGTG CGGAAGGAGA TGAAACAGCA GGAAGGGCCT 
GTGTTCTCAC GAACATTTGG GGACACAGAG GCACAGGTTG GGGATGTGCT GCGGCTAGAG 
TGTGTGCTGG CCACCAAGAC TGATATGCGG GCCTGCTGGT TGAAGGATGG CATCGAGTTA 
ACAGATGGGC GCCATTACCA CATAGACCAG CTCAAGGATG GTACCTGCTC TCTGCTGGTC 
ACTGGCCTGG CCCCCACTGA CTCTGGCCGT TACACCTGTC AGGTGAGCAC CAAGTCTGGC 
CGTGTGAGCC ACAGTGCCTG CGTGGTGGTC AGTGGGACAG AGAGCGAGGC CGAGAGCTCC 
TCTGGGGGCG AGCTGGATGA TGCTTTCCGC CGGGCAGCGA GACGCCTGCA CCGCCTCTTC 
CGCACCAAGA GCCCAGCTGA GCTTTCAGAG GAGGAACTCT TCCTCAGCGC TGATGAAGGC 
CCCGGGGAGC CAGAGGAGCC CGCAGACTGG CAAACATACC GAGAGGATGA GAACTTTGTG 
TGCATCCGTT TTGAGTCCCT TGCAGAGGCC CGCCAGGCAG TCACCTGCTT CCGAAACATG 
TTTGCCACTA TGGGCATCGG GGTGGAGATC AGCCTAGGGG AGCAGGGACC CCGGGGAGTG 
GAGATGCGCA TCGGCAAGGT GGCCCCTACT GTCACCCCTG CAGTGCCGCT TGCAAAGACA 
CCTGGCCTGC AGACTTCAGA TGCTGCCCCA GTGTTCCTGA CCGAGCTGCA GAACCAAGAT 
GTGCAGGATG GATACCCCAT GAGCTTCGAC TGCGTGGTAA CGGGCCAGCC TGTGCCCAGT 
GTGCGCTGGT TCAAGGATGG GAAGCTGCTA GAAGAGGATG ACCACTATAT GATCAATGAG 
GACCAACAGG GGGGTCACCA GCTCATCATC ACAGCTGTGG TGCCGGCAGA CATGGGTGTC 
TACCGCTGCC TGGCGGAGAA CAGCATGGGC GTCTCCTCCA CCAAGGCTGA GCTTCGTGTG 
GAATTGACCA GCACAGACTA TGATACTGCT GCGGATGCTA CTGAGACCTC ATCCTACTTC 
AGCGCCCAGG GATACCTGTC CAGTCGGGAG CAAGAGGGAA CGGAGTCAGA TGAGGGGCAG 
CTTCCCCAGG TGCTGGAGGA ACTGAAAGAC CTCCAAGTGG CCCCCGGGAC ACGCCTGGCC 
AAGTTCCAGC TCAAGGTGAA AGGCTATCCA GCTCCCAAAC TGTATTGGTT CAAAGATGGC 
CAGCCCCTGA CCACGTCTGA CCACATCCGC ATGACTGACA AGAAGACCCT GCACACCCTG 
GAGATTGTCT CGGTCACTCG GGAGGACAGC GGCCAGTATG CAGCCTACAT CAGCAATGCT 
GTGGGTGCTG CCTATTCGTC AGCCCGGCTT CTGGTCCGAG GTCCCAGTGA ACCAGAAGAG 
AAGCCAGCAT CAGATGTTCA TGAGAGGCTG GTGCCACCCC GAATCCTGGA GAAGTTCACC 
CCCAAGAAAG TGAAGAGGGG CTCCAGCATC ACCTTTTCAG TGAAGGTGGA AGGACACCCG 
GCCCCCAGTG TGCATTGGCT CAAGGAGGAG GCAGAGAAGG GAGTCCTGTG GATTGGCCCT 
GACACCCCGG GCTACACCAT GGCCAGCTCT TCCAAGCAGC ATAGCCTGGT CCTGCTGGAC 
GTAGGCCGAC AGCACCAGGG CACCTACACA TGTATTGCTA CCAACCCTGC TGGCCAGGCG 
CTCTGCTCTG CCAGCCTGCA CATCTCTGGC TTGGCCAAAG AAGAAGAGCA GGAGAGAGTG 
AAGGAGGCCC TCATTTCCTC TTTCCTGCAA GGGACAAGCC AAGCTGTCTC AGCCCAGATG 
TCAGAATCCG CAGGTTTTGC TGATCTTGTC GGGCAAAGCA AAGGCGAGTC TCTGGTGGCT 
GAGGAGGCCC ACAGTCACCT GTCCCTTGCT GAGGTGGGCA CTGAAGAGTT CCTGCAGAAA 
CTCACCTCGC AGATCACGGA GATGGTATCG GCCAAGATCT CTCAGGCCAA ACTCCAGGTG 
CCTGGAGGTG ACAGCGATGA AGAGACCAAG ACACCATCTG CTTCTCCTCG GCATGGCCGG 
TCACGTCCTT CCTCCAGTGT TCAAGAGTCC TCCTCAGAGT CAGAGGATGG GGACTCCCGT 
GGTGAGATCT TTGACATCTA TGTGGTCACA GCTGACTATC TGCCACTGGG AGCTGAGCAG 
GATGCCATCA TTCTGAGAGA AGGCCAGTAT GTGGAGGTCC TTGACTCTGC CCATCCCCTG 
CGCTGGCTTG TCCGGACCAA GCCCACCAAA TCCAGTCCTT CCAGGCAGGG CTGGGTGTCA 
CCTGCCTACC TGGATAAGAG GCTCAAGCTG TCTCCTGAGT GGGGGCCCAC TGAGGCCCCC 
GAGTTCCCTG GCGAGGCTGT GTCTGAGGAT GAGTATAGAA CGAGGCTGAG CTCTGTCATC 
CAGGAGTTGC TGAGTTCAGA GCAGGCTTTT GTGGGTGAGC TGCAGTTCTT GGAGAGCCAC 
CACATGAAGC ACCTGGAGCG ATCTCCCCGA GTACCCGCAG CTGTGGCCAG CCAGAAGACA 
GTCATCTTTC GTAATGTGCA GGACATCAGC CATTTCCACA GCAGCTTCTT GAAGGAGCTG 
CAGGGCTGTG GCACCGACGA TGATGTGGCC ATGTGCTTCA TCAAGAACCA GGAGGCCTTT 
GAGAAGTACC TCGAGTTCCT GGTGGGCCGC GTGCAAGCTG AATCAGTGGT TGTCAGCACC 
CCAGTCCAGG AGTTCTACAA GAAATATGCA GAAGAGACAC TGTCAGCCAA GGACCCCACA 
CAGCCACCCC CACCTCCTCT TCAGCACTAC CTGGAGCAGC CAGTGGAACG GGTGCAGAAA 
TACCAGGCCT TGCTGAAGGA GCTAATCCGC AACAAGGCCC GCAACCGGCA GAACTGCGCG 
CTGCTGGAGC AGGCCTATGC TGTGGTGTCT GCCCTGCCTC AGCGCGCCGA GAACAAGCTG 
CACGTTTCTC TCATGGAGAA CTACCCAGGA ACCCTGGAGG CCCTGGGAGA ACCTATCCGC 
CAGGGCCACT TCATAGTGTG GGAGGGGGCC CCAGGGGCCC GGATGCCTTG GAAGGGCCAC 
AACCGGCACG TCTTCCTCTT CCGAAACTAC CTGGTGATCT GCAAGCCCCG AAGAGACTCT 
CGAACCGACA CCTTCAGCTA TGTGTTCCGG AACATGATGA AGCTGAGTAG CATCGACCTG 
AATGACCAAG TAGAGGGGGA TGACCGCGCC TTTGAGGTGT GGCACGAACG GGAAGACTCT 
GTGCGCAAGT ACCTGCTGCA GGCACGGACC GTCATCATCA AAAACTCCTG GGTGAAGGAG 
ATCTGTGGCA TCCAGCAGCG CCTGGCCCAG CCTGTGTGGC GTCCCCCTGA GTTTGAAGAG 
GAACTAGCGG ACTGCACAGC CGAGCTGGGT GAAACGGTCA AGCTAGCATG CCGAGTGACG 
GGCACACCTA AGCCTATTGT CAGCTGGTAC AAAGATGGGA AGCCAGTGGA GGTGGACCCA 
CACCACATCC TCATTGAAGA CCCTGACGGC TCCTGCACCC TCATCTTGGA CAACCTTACT 
GGCATAGACT CTGGCCAGTA CATGTGTTTT GCGGCCAGTG CTGCTGGCAA CGCCAGCACC 
TTGGGGAAGA TTCTAGTACA AGTGCCCCCA CGGTTTGTGA ACAAGGTCCG GGCCACACCC 
TTTGTGGAGG GAGAGGATGC ACAGATCACC TGCACAGTGG AAGGAGCCCC GTACCCTCAG 
ATCAGGTGGT ACAAGGATGG TACCCTGCTA GCCCCGGGCA ACAGGTACCG GATGTTGAAT 
GAACCCCGCA GTGGTGTGCT GGTGCTGGTG ATCCAGGCGG CCAGCAAGGA GGACCTGGGA 
CACTATGAAT GTGAGTTGGT GAACCGGTTG GGCTCAACAC GTGGTGGTGG AGAACTATAC 
ATGCAGAGCC CTGCACTGCG TGCCCGGGAC CAGCACCACC GGGAACAGAT TGTGGCTGCC 
GTAGAAGTCA CTGAGCAGGA GACAAAAGTC CCCAAGAAAA CCGTCATCAT AGAGGAGACC 
ATCACCACCG TAGTGAAGAG TCCGCGTGGC CGACGACAGT CCCCCGGCAA GTCTCCCTCT 
CGTTCACCTT CCCGCCGCTC TGCCAGTCCA CGGAGACCAG GGCTGTTGGC CCCCGAGAGG 
CTGTATCCAC CAGGGACCAG CCCATCCCGG AGGCTTGAAG TAGAACAAGG CAGGAAAGCC 
CCGGTGCCTG CATTGTATGT GACAGAAGCA GAGGTCCACG CTCCAGCCTC GCAGTCCCAG 
CCCAAGTGGT TAGAGGTGGA GGAAACCATT GAAGTCCGGG TGAAGAAGAC GGGGTCACGG 
GGTGCATCTC CTGTCCGAGA GATGACCAGC CGTGGAGAAG GAATCCTCTT CACACTGCCT 
GGTGGGATCC CTGGTAGGGA CCCAAATGCC AACAACTCCA ACAACAAGAG TGTGTACCAG 
GAAGCCCGGA CCTGGGGTCC CGCTGTGGTC CATGTTGGTG AACCTTTCAT CTTCCAAGTG 
GACTCGGTGG GCAATGTGGA CTGGGTAGCT GCTAGCCCTG AGCCAGAGCA GGTCAGAGCC 
TCCCAGAAGG AAGAGAACAC TGAAAGGCAG GAAGGATGCA GTGATGGAGA CGAGAATACC 
TTCCTGATGG AAGAACCACA GGACACGGAT AGCCTTCAGG GCCGTGACCC CAAAATCCTC 
ACACACAATG GCCGGGTGCT GACATTGGCT GACCTGGAAG ATTATGTGCC CCAGGAAGGA 
GAGACTTTTG GCTGTGGGGA CTCCACCCCC AGCACCCCTG ATGAACCTCC CTGTGAAGTC 
TCCGTGCTCC AGAGAGAGAT CAGCGAGCCC ACGGTGGGGC AACCTGTCCT GCTCAATGTG 
GGGCGTCCTC CAGGCACCGG TGCCACTCCC AGCTTCTTCA GGCCAGGTTC CCAGGTCCAC 
AGCCCTGAGA GTGTCTCCTT CCTTTTGCGT GAGGCCTGGT CAGGTCCAGT GAGTGCCGCC 
CCTTGGACAA GCTCCTTCCA TACCCATGTC CAGAGTTCTG TAGATGGTAG CCATGGGAGC 
TTCAAGACAG AGGTCTCCAC CCAGACAGTC AGCTTTGGGG CCGTAGGAGA GACAGTCACT 
CTTCATATTG ACCCAGATGG TGGCGAGGCT CCAGGCCCCT CCCAGGGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Obscn ( NM_001171512.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001164983.2 Mus musculus obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), transcript variant 1, mRNA.

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CloneID	OMu11845
Clone ID Related Accession (Same CDS sequence)	NM_001171512.2
Accession Version	NM_001171512.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 24099bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Mus musculus(house mouse)
Product	obscurin isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL645854.10 and AL662809.14. On or before Jul 6, 2018 this sequence version replaced NM_001003914.1, XM_003689264.1, NM_001171512.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). The RefSeq Project created this record to better support genomic annotation of the full gene length but the combination of exons and splice sites still needs to be experimentally confirmed. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The genomic coordinates used for the transcript record were based on genomic predictions and alignments of transcripts from different species. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849390 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACCACT CCTTCAGCGG AGCACCCCGC TTCCTGACGC GGCCAAAGGC CTTTGTGGTA 
TCTGTTGGCA AGGATGCCAC GCTGAGCTGC CAGATCGTGG GCAACCCCAC GCCACACGTG 
AGCTGGGAGA AGGACCGGCA GCCAGTAGAG GCAGGAGCGC GCTTCCGCCT GGCCCAGGAC 
GGGGATGTGT ACCGCCTCAC AATTCTCGAT CTGGCGCTAG GTGACAGCGG GCAGTATGTG 
TGTCGCGCGA GGAACGCCAT AGGGGAGGCC TTCGCCGCCG TCGGCCTGCG AGTGGACTCG 
GAGGGCACGT GTGCCGAGCA GGCGCCCCAC TTTCTGCTGC GGCCCACATC CATTCGCGTG 
CGCGAGGGCG CAGACGCCAC CTTCCGATGT CGCGTTGGAG GCTCACCACA ACCTGCTGTG 
AGCTGGTCCA AAGATGGGCG GCGCCTGGGC CCACCCGATG CCCCCCATGT GCGTGTGGAA 
GAACACGGGG AGTCGAGCGC GCTTCGCATC CGTTCGGCAA GGCCTCGCGA TGGTGGCACC 
TACGAAGTCC GAGCAGAAAA TCCGCTGGGC TCTGCCAGCG CTGCCGCCGC TCTGGTGGTG 
GACTCGGACG CCGAGGTTGC CGGACCACCC GGCACCTCCA CCGCCACGCT CCTGGCGCAC 
CTGCAGCAGC GGCGGGAGGC CATGCGCGCA GAGGGCATAC CCCCTTCTCC ACCCGGCGCT 
GGCACGCGCA CCTGCACGGT GACCGAAGGC AAACACGCGC GCCTCAGCTG TTTTGTGACC 
GGCGAGCCCA AGCCCGAGAC AGTGTGGAAG AAGGACGGGC AGCTGGTGAC CGAGGGCCGG 
CGACACGTAG TGTATGAGGA CGAGCAAGAG AACTTCGTCC TTAAGATTCT TTTCTGCAAG 
CAGTCCGACC GCGGCCTCTA CACCTGCACA GCGTCCAACC TCGTGGGCCA GACCTACAGC 
TCGGTGCTGG TGGTCGTGAG AGAGCCGACG GTGCCCTTCA AGAAGCGGCT GCAGGACCTG 
GAGGTACGAG AGAAAGAGTC TGCTACATTC CAGTGCGAGG TGGCTCAGCC AGCTACCGAG 
GCGGCGTGGT TCAAGGAGGA GACCCGGCTA TGGGCCAGCG CCAAGTACGA CATCGAGGAG 
GAGGGCACCG AGCGCCGGCT GACCGTGCGC AACGTCTCGG CAGACGACGA CGCTGTGTAC 
ATCTGCGAGA CCACAGAGGG CAGCCGCACG GTGGCAGAGC TCTCTGTTCA AGGAAACTTG 
ACCAGAAAGC TGCCTCGGAA GACAGCAGTG CGCACTGGAG ACACAGCCAT CTTTTGGGTG 
GAGCTGGCTG TCCCCGAAGG CCCTGTCCGG TGGCTACGGA ACCAGGAGGA GATGGTGGCA 
GGGGGTCGGG TTGCCATCAC TGCAGAAGGC ACGTGCCACA CACTGACCAT CTTCCAGTGC 
ACCTTGGAGG ACATGGGTGA GGTGGCCTTT GTGTCTGGTG GCTGCCGGAC GACCACCCAG 
TTCTGTGTAT CAGCGCCCAG GAGGCCACCC CTGTACCCTC CTGCTGACCC TGTTGTAAAG 
GCCAAGACAG AGAGTTCTGT GACCCTCAGC TGGTCCGCAC CACCCCATGG GGACCGCCCT 
GTCACTATTG ATGGCTATGT GTTGGAGAAG AGGAAGCTGG GTGCCTATGC CTGGAGCAGG 
TGTCACGAAG CTGGATGGCT GGCCACAACT GAGTTTACCA TCACTGGTGT GGCTGAGGAG 
GGGGATTTCC AGTTCCGAGT GTCAGCCATC AATCACTTTG GCCAGGGTCC TTACCTTGAA 
TTTCCAGGGA CCATGCACTT GGTCCCCATG CTGGCTGTAA AGACACCTCT GAAGGCGGTG 
GAGGCAGTGG AGGGTGGTGA GGTCACTTTC TCCGTGGACC TCACGGTGGC CTCTTCGGGC 
GAATGGTTCC TGGATGGGGA GGCCTTGAAA GCGAGCAGTA TATACGTGAT CCGTTGTGAC 
CGCACCCGGC ATATGCTCAC CATCAGAGAG GTGCCCGCCA GATTGCATGG GGCACAGCTG 
AAGTTTGTGG CTAATGGCAT TGAAACTAGC ATCCAAATGG TGGTCCGAGC GGCTCTGGGG 
CTGCCCAGCA GTAAGCTTCC TGCTGCGGCT GCCCGGGAGG TGCTGGCCCA GTTGCACGAG 
GAGGCACAGC TGCTGGCTGA GCTGTCGGAC CAGGCTGCTG CTGTGACTTG GCTGAAGGAT 
GGTCGTGAGC TGTCCCTAGG GCCCAAGTAT GAGATGCAGG TGTCAGCTGG GAGGCGAGCA 
CTGCTGGTGC GGGACGTGGC ACAGGATGAC GCTGGCCTCT ATGAGTGTGT CAGTCGTGGG 
AGCCGCACTG CCTACCAGCT GTTGGTGCAA GACATAACAG ATGGCTACCG TGACTGGGGC 
CCAGCAGGAC CTCAGAAGCA CATGTGCAAG TGTGCTGGGG CAAAGATAGC GAGATACTTG 
GGTTCCTCTT GCTACCGCTT CTTGCAGTAT GACAAGGGGG TATGGCATTG GCTGGAGGCA 
GCTTTGGACA CCAGGCAGGG CAAGGGTACC TCCTCCTGCT CCCTGCATGA AAAACCCAAG 
CTGGTATTTG CCAAGGGGCA GCAGGCACAC AGTGAGGTGA AGGCAGAGGC GGGGGCCAGC 
GCCACACTGA GCTGCGAGGT GGCCCAGGCC CAGACTGAGG TGACATGGTT CAAGGACGGG 
AAGAAGCTGA GCTCCAGCTC GAAGGTGCGC ATGGAGGCCT CGGGCTGCTC CAGGAGGCTG 
GTGGTGCAGC AGGCGGGCAA GGCGGATGCT GGGGAGTACA GCTGCGAGGC CGGGGGACAG 
AAGCTCTCCT TCCGCCTGGA CGTGGCAGAG CCCAAGATGG TGTTTGCCAA GGAGCAGCAG 
GCACGCAGCG AGGTGAAGGC CGAGGCGGGG GCCAGCGCCA CACTGAGCTG CGAGGTGGCC 
CAGGCTCAGA CTGAGGTGAC ATGGTTCAAG GACGGGAAGA AGCTGAGCTC CAGCTCGAAG 
GTGCGCATGG AGGCCTCGGG CTGCTCCAGG AGGCTGGTGG TGCAGCAGGC GGGCAAGGCA 
GATGCTGGGG AGTACAGCTG CGAGGCCGGG GGACAGAAGC TCTCCTTCCG CCTGGACGTC 
ACAGAGCCCA AGCTGGTGTT TGCCAAGGAG CAGCAGGCAC GCAGTGAGGT GAAGGCAGAG 
GTGGGGAACA GTGCCACACT GAGCTGCGAG GTGGCCCAGG CCCAGACTGA GGTGACATGG 
TTCAAGGACG GGAAGAAGCT GAGCTCCAGC TCGAAGGTGC GCATGGAGGC CTCGGGCTGC 
TCCAGGAGGC TGGTGGTGCA GCAGGCGGGC AAGGCGGATG CTGGGGAGTA CAGCTGCGAG 
GCCGGGGGGC AGAAACTCTC CTTCCGCCTG GACGTGGCAG AACCCAAGCT GGTGTTTGCC 
AAGGAGCAGC AGGCACGAAG TGAGGTGAAG GCAGAGGCAG GGAACAGTGC CACACTGAGC 
TGTGAGGTGG CCCAGGCACA GACTGAGGTG ACATGGTTCA AGGACGGGAA GAAGCTGAGC 
TCCAGCTCAA AGGTGCGCAT GGAGGCCTCG GGCTGCTCCA GGAGGCTGGT GGTGCAGCAG 
GCGGGCAAGG CGGATGCTGG GGAGTACAGC TGCGAGGCCG GGGGACAGAA GCTCTCATTC 
CATCTGGACG TCACAGAACC CAAGCTGGTG TTTGCCAAGG AGCAGCAGGC ACACAGTGAG 
GTGAAGGCAG AGGCGGGGGC CAGTGCCACC CTGAGCTGCG AGGTGGCCCA GGCCCAGACT 
GAGGTGACAT GGTTCAAGGA CGGAAAGAAG CTGAGCTCCA GCTCAAAGGT GCGCATGGAG 
GCCTCGGGCT GCTCCAGGAG GCTGGTGGTG CAGCAGGCGG GCAAGGCGGA TGCTGGGGAG 
TACAGCTGCG AGGCCGAGGG ACAGAAGCTC TCCTTCCGCC TGGACGTGGC AGAGCCCAAG 
CTGGTGTTTG CCAAGGAGCA GCAGGCACGC AGCGAGGTGA AGGCAGAGGC TGGGGCCAGT 
GCCACACTGA GCTGTGAGGT GGCCCAGGCC CAGACTGAGG TGACATGGTT CAAGGACGGG 
AAGAAGCTGA GCTCCAGCTC GAAGGTGCGA GTGGAGGCCT CGGGCTGCTC CAGGAGGCTG 
GTGGTGCAGC AGGCGGGCAA GGCGGATGCT GGGGAGTACA GCTGCGAGGC CGGGGGCCAG 
AAGCTCTCCT TCCGCCTGGA CGTCGCAGAG CCCAAGCTGG TGTTTGCCAA GGAACAGCAG 
GCAAACAGCG AGGTGAAGGC CGAGGCGGGG GCCAGCGCCA CACTGAGCTG CGAGGTGGCC 
CAGGCCCAGA CTGAGGTGAC ATGGTTCAAG GACGGGAAGA AGCTGAGCTC CAGCTCGAAG 
GTGCGCGTGG AGGCCTCGGG CTGCTCCAGG AGGCTGGTGG TGCAGCAGGC GGGCAAGGCG 
GATGCTGGGG AGTACAGCTG CGAGGCCGGG GGGCAGAAGC TTTCCTTCCG CCTGGACGTG 
GCAGAGCCCA AGCTGGCGTT TGCCAAGGAG CAGCAGGCAC ACAGCGAAGT GAAGGCAGAG 
GCGGGGGCCA GCGCCACACT GAGCTGCGAG GTGGCCCAGG CCCAGACTGA GGTGACATGG 
TTCAAGGATG GGAAGAAGCT GAGCTCCAGC TCGAAGGTGC GCGTGGAGGC CTCGGGCTGC 
TCCAGGAGGC TGGTGGTGCA GCAGGCGGGC AAGGCGGATG CTGGGGAGTA CAGCTGCGAG 
GCCGGGGGAC AGAAGCTCTC ATTCCGCCTG GACGTGGCAG AGCCCAAGCT GGCGTTTGCC 
AAGGAGCAGC AGGCACACAG CGAGGTGAAG GCAGAGGCGG GGGCCAGCGC CACACTGAGC 
TGTGAGGTGG CCCAGGCCCA GACTGAGGTG ACATGGTTCA AGGACGGGAA GAAGCTGAGC 
TCCAGCTCGA AGGTGCGCGT GGAGGCCTCG GGCTGCTCCA GGAGGCTGGT GGTGCAGCAG 
GCGGGCAAGG CGGATGCTGG GGAGTACAGC TGCGAGGCCG GGGGTCAGAA GCTCTCCTTC 
CGCCTGGACG TGGCAGAGCC TAAGCTGGCG TTTGCCAAGG AACAGCAGGC ACACAGCGAG 
GTGAAGGCAG AGGCGGGGGC CAGTGCCACA CTGAGCTGCG AGGTGGCCCA GGCCCAGACT 
GAGGTGACAT GGTTCAAGGA CGGGAAGAAG CTGAGCTCCA GCTCGAAGGT GCGCGTGGAG 
GCCTCGGGCT GCTCCAGGAG GCTGGTGGTG CAGCAGGCGG GCAAGGCGGA TGCTGGGGAG 
TACAGCTGCG AGGCCGGGGG ACAGAAGCTC TTCTTCCGCC TGGATGTGGC AGAGCCCAAG 
CTGGTGTTTG CCAAGGAGCA GCAGGCACAC AGTGAGGTGA AGGCCGAGGC GGGGGCCAGC 
GCCACCCTGA GCTGCGAGGT GGCCCAGGCC CAGACTGAGG TGACATGGTT CAAGGACGGG 
AAGAAGCTGA GCTCCAGCTC GAAGGTGCGC GTGGAGGCCT CGGGCTGCTC CAGGAGGCTG 
GTGGTGCAGC AGGTGGGCAA GGCGGATGCT GGGGAGTACA GCTGCGAGGC CAGGGGACAG 
AAGCTCTCCT TCCGCCTGGA CGTGGCAGAG GCCGAATCCC AGATTCCGGA GAGACCCAGC 
CGCAGGGAAC CTCTGGTTGT CAAGGAACAT GAGACCATTA TCCTGACTGC CACAATAGCT 
GCACCCTCTG TGGCTGCTGT GACCTGGCTC AAAGATGGAG TGGAGATCCG CCGCAGTAAG 
CGGCATGAGG CCACCAGTCT GGGTGATACC CATACCCTGA CCGTGAGAGG CGCACAGGTC 
CTGGACAGTG CCATCTACAG CTGCCGTGTT GGCAAGGAAG GTCAGGACTT CCCGGTGCAG 
GTAGAAGAGG TGGCCGCCAA GTTCTCCAAA CCCCTGGAGC CCGTCGAAGG GGAGCTGGGT 
GGCACCGTGA TGCTGGTTTG TGAGCTGAGC CCGGAGCAGG CTGAGGTTGT GTGGCGCTGT 
GGGAACACAC AGCTGCGGCC AGGCAAGCGC TTCCAGATGA CATCAGAGGG GCCTAGGCGC 
ACGCTGACCG TGTCTGGCCT TCGAGAGGAT GACGCAGAGG AGTATGTGTG TGAGAGCCGG 
GATGACCGCA CCAGCGCACG GCTCACTGTT AAAGTTCCCC GAGTGGTCAA GTTTACGTCT 
GGATTGAGTG CCATGGTCGC AGAGGAGGGC CAAGAGGCCA CCTTTCAGTG TGTCGTGTCC 
CCCAGCGATG CAGGGGTCAC ATGGTACAAG GACGGGATGC AGCTGCAGCC TAGCGAGAAG 
TTTGTTATGG TAGAGAGTGG GGCCAGCCGC AGCTTGACTA TCTTGGGCCT GACCCTGGAG 
GATGCCGGTC AAGTCACAGT GGAGGCTGAG GGGGCTTCAT CTTCTGCTGC CCTCCGGGTC 
CGAGAGGCAC CGGTCCTCTT CAAAAAGAAG CTGGAGCCAC AGACAGTGGA GGAGAGGACC 
TCTGTGACAT TGGAGGTGGA GCTGACGCGG CCCTGGCCCG AGGTGAAGTG GACACGGAAT 
GCTGCCGTCC TGACACCCAG CGAGAACGTG GAGATCCGCG CTGAGGGTGC TCGGCACTGT 
CTGGTGCTGC GCAGCGTGGG CTTTGCTGAC CGCGGCTTCT TTGGCTGTGA GACACCAGAT 
GATAAGACTC AGGCCAAGCT CAATGTAGAA ATGCGGCAGG TCCGGCTGGT TCGCGGTCTG 
CAGGAGGTGG AGGCTAAGGA ACAGGGCACG GCCTCGATGG ATGTGGAGCT GTCCCATGCC 
GAGGTGGAGG GCAGCTGGAC CCGAGATGGC CTGCGACTTC AGCCTGGACC CAAATGCCAC 
CTGGCCGTAC AAGGCCCTGT CCACATCCTC ACACTCTCGG CGCTGCAGCC ACAGGACAGT 
GGGCTGGTGG CCTTCAGGGC CGAGGGCGTG CACACGTCTG CGAGGCTCAT AGTCACTGAG 
TTGCCCGTGA GCTTCACCAG AGTACTACAG GATGTGGTGG CCACGCAGAA GGAGAAGGTC 
ACCCTGGAGT GTGAGCTGTC GAGGCCTGTG GATGTGCGCT GGCTGAAGGA TGGTGTGGAG 
CTGCGGGCAG GCAAGGCCAT AGGCATAGTG GCCCAGGGAA CCTGCAGGAG TCTCGTTATC 
TACCGCTGTG AGACTGGGGA CCAGGGTGTC TATGTATGTG ATGCTCTTGA TGCTCAGACC 
TCTGCCTCTC TGAGGGTGCA AGGGAGGACA TACACGCTTA TCTTCCGGAG GGTACTGGCA 
GAGGATGCAG GGGAGGTCAA GTTTGTAGCT GAGAACGCAG AATCAAGAGC TCACCTCCGA 
GTGAAAGAAC TGCCCGTGAC CCTCCTGCGC CCACTGAGGG ACAAGATTGC CATGGAAAAA 
CACCGTGGAG TGCTGGAGTG CCAGGTGTCC CGGGCTAGTG CCCAGGTGCG GTGGTTCAAG 
GGCGGAGTCG AGCTGCAGTC TGGGCCCAAG TACGAGGTGG TCAGTGACGG CCTTTACCGC 
AAGCTGGTCA TTAATGACGT GCAGCCTGAG GATGAAGATA CGTACACCTG TGACGCTGGC 
AACGTCAAGA CCAGTGCCCA GTTCTTTGTG GAAGAGCAAT CCATCACTAT TGTGCGGGGA 
CTGAAGGACA TGACAGTGAT GGAGCCTGCC CCTGCCTGGT TTGAATGTGA GACATCCATC 
CCTTCCGTGA GGCCACCCAA GTGGCTCCTT GGTAAGACTG TGCTCCAGGC AGGGGGGAAC 
GTGGGACTGG AGCAAGACGG CACCGTGCAC CGGCTGACAC TGCACAAGAC CTGCTCTACC 
ATGACCGGGC CTGTGCACTT CACTATCGGC AAGTCCCGCT CCTCTGCCCA GCTGGTTGTC 
TCAGACATTC CTGTGGTACT GACACGGCCT CTGGAGCCCA AAGCAGGGCG TGAACTGCAG 
TCAGTAGTCC TGTCCTGTGA CTTCAGGCCA GCCCCCAAGG CTGTGCAGTG GTACAAGGAT 
GACACACCCC TGTCCCCGTC AGAAAAGTTC AAGATGGCGC TGGAGGGCCA GATGGCAGAG 
CTGCGCATAC TCCGGCTCAC GCCAGCTGAT GCTGGGGTCT ACCGGTGCCA GGCGGGTAGC 
GCCCAGAGCA GTGCTGAGGT TACTGTGGAA GCTCGGGAGG TGACAGTGAT TCAGCCACTG 
CAGGATGCAG AAGCCATGGA GGAAGGCCGG GTCTGCTTCT CCTGCGAGCT GTCCCATAAG 
GATGAAGATA TCGAATGGTC ACTCAATGGT ACACCCCTGT ACAATGACAG CTTCCATGAG 
ATCAGCCATG AGGGCTGTCT CCACACCCTG GTGCTGAAGA GTGTCCGGCA GGCTGACACA 
GGCACCGTGT GCGCCACCTC CCCCAAGGTG TCCGTTTCCG CCCGGCTGGT GGTTAAAGGC 
AAGCCAGTGG TGTTCCTGAA AGCACTGGAT GACGTATCTG CAGAAGAGCG TGGCACGCTG 
ACCCTGCAAT GCGAGGTCTC CGACCCCGAG GCACGCGTGG TTTGGCGCAA AGATGGTGTG 
GAGCTTGGTC CCAGCGACAA GTATGATTTC CTACATAAGG CAGGTGCCCG GGGCCTTACG 
GTCCATGACC TGAGCCATGA GGATGCTGGA CTGTACACCT GCCAGGTGGG CAGTAAGGAG 
ACCCAGTCCA AGGTCAGCGT ACATGATCTT CACGTGGGCA TCACCAAGAG GTTAAAGACA 
GTGGAGGTGC TGGAGGGAGA GAGCTGCAGC TTTGAGTGTG TCCTTTCCCA CGAGAGTCCC 
AGTGACCCAG CAGTGTGGAC GGTCGGTGGG AAGACAGTGG GTGGTTCTGG CCACTTTCAC 
GCCGTTCGGC AGGGCCGCAA ATACACCCTG ACAGTCAAAG ATGCTGCACT CAGTGATGCA 
GGAGAGGTGG TCTTCTCGGT GCTGGGCCTC ACTTCCAAGG CCTCGCTCAT CATCAGAGAG 
AGGCCAGTGG ACATCACCAA GCCCCTGGAG GACCAGCGGA CGACGCTTGG GGAAGATGTA 
ATGCTAAGCT GTGAGCTGTC CAGGGCAGGC ACCTCTGTGC GCTGGCTGAA AGACGGGAAG 
GCCATCAGGA AGAGCCAGAA GTATGACCTG CTCAGTGAAG GCACGCGGGC TGTGTTGGTT 
GTCCGCAAGG CCTCACTCAA GGATTCAGGG GAATACACCT GCGAGACAGA AGCTTCGAAA 
AGCACTGCCA AGCTCTGTGT GGAAGAAAAG GCAAACCGGT TCACGGAGGA GCTGGCTGAC 
CTGCAGGTGG AAGAGAAGGG CAGAGCTGTG TTCACATGCA AGACAGAGCA CCCAGCATCT 
GTCGTGACCT GGCGCAAAGG CCTCCTGGAG CTGCGCGCCT CAGGGAAGCA TGTCCCCAGT 
CAGGAAGGCT TGACCCTGAA GCTCACCATC AACGCCCTGG AGAGGACAGA CAGTGACACT 
TACACCTGTG ACATCGGCCA AGCCCGGACC CAGGCACGGC TCCTCGTCCA CGGCCAGAAA 
GTGCGCGTTA TTGAGGACCT AGAGGACACT GCTGTCCAGG AGGGCTCCTC TGCTAAGTTT 
TGCTGCCGCA TCGCTCCTGC TGACTACGGC CCCGTGCACT GGTTCCTGGA TAAGACCCCC 
TTGCACAGCA ATGAGCTGAA TGAGATCACT GTCCAGCCTG GAGGCTATCA CGTGCTCACC 
CTGCGGCAGC TGGCACTCAA GGACTCAGGC ACTGTCTACT TTGAGGCGGG TGACCAGCGA 
ACCTCAGCTG CCCTGCGGGT GACTGAGAAG CCGAGCATCT TCTCTCGGCC ACTCACAGAC 
GTCACAGTCA CAGAAGGCGA GGACCTGACT CTGGTCTGTG AAACCACCAC TGTGGATAGC 
TCTGTGCGCT GGACCAAAGA TGGGAAGACA CTGAGGCCGT CTGCACGATG CCAGCTGAGC 
CATGAAGGCT GTCAGGCCCA GCTGCTCATC ACTGCCACCA CCCCACAAGA TGGTGGGCGG 
TACAAATGTG AGATTGGTGG AGCCTCCAGC AGCTCCATTG TCAGGGTCCA TGCTCTGCCA 
GTGCGGTTCA GGGAGTCCCT GAAGGACGTG GAGGTACCAG AGGGCAAGGC CGCCACACTG 
CGCTGTGTGC TGTCATCCGT GGCTGCACCT GTGGAGTGGC GTCATGGAGA TGATGTCCTG 
AAATCCAGCA ACAAGTATAG CCTGCGCCAA GAGGGTGCTG TGCTGGAATT GGTCATCCGA 
GACCTGCAGC CCCAGGACAG TGGGCAATAC TCATGCTCCT TTGGGGACCA GACAACTTCA 
GCCACACTCA CAGTGAAAAC CTCTTCTGCC CAGTTCGTAG GGAAACTGAG AAACAAGGAG 
GCCACAGAAG GGACCACGGT CACACTTCGG TGTGAGCTGA CCAAAGAGGC CCCCGTGGAG 
TGGAAGAAGG GAACAGAGAC CCTGAGAAAT GGGGACAAAT ACAGTCTGAA GCAGGATGGA 
GCTGTGTGTG AGCTGCAGAT CTGTAGTCTG CTGGTGGCAG ATGCAGGGGA GTACTCGTGT 
GTGTGTGGGC AGGAGAAGAC TTCAGCCACG CTGACTGTCA AGGCTCTGCT TGTCCACTTT 
GTCAGAAGGC TCAGGAGCAA GGAGGCCACA GAAGGAGACA CGACCACACT GCAGTGTGAA 
CTGAGCAAGG CTGCCCCCGT GGAGTGGAGG AAGGGAACAG AGACCCTGAG AGATGGGGAC 
AGATACAGCC TGAAGCAGGA TGGGGCTGTG TGTGAGCTGC AAATCCGCAG CCTGACCATA 
GCAGATGCTG GCGAGTACTT GTGCACGTGT GGACAGGAAA AGACCTCAGC CACGCTGACC 
GTCAGGGCCC TTCCAGCTAA GTTCAAAGAC AGTCTGAAGA ATGAAGAGGC TACAGAAGGC 
ACCACAGCTA CACTGAGCTG TGAACTGAGC AAGGCAGCTC CGGTGACATG GAAGAAAGGA 
CCGAAGACCT TGCAAAGTGG AGACAAATAT GTCCTGAGGC AGGATGGAGC TGTGTGTGGA 
CTACAGATCC ATGGCCTGAC CATGGCTGAT GCTGGGGAGT ACTCGTGTGT GTGTGGGCAG 
GAGAAGACGT CAGCCACGCT GACTGTCAGG GGCTTGCCTG CCAAATTTAT AGAAGATCTG 
AGAAGCCAAG AAGCCACAGA AGGGGCCACA GCAATCTTAA GATGTGAGCT GAGCAAGGCT 
GCTCCTGTGG AGTGGAGGAA AGGGTCTGAG ACCCTGAAAG ATGGGGACAG ATACACCCTG 
AGGCAGGATG GGGCCGTATG TGAGCTGCAG ATCCGTGGCC TGGCTGTGGT GGATACTGGG 
ACATACTCGT CCCTGCCCAC CAAGTTCACA GAGGGTCTGA GGAATGAAGA GGCCACGGAA 
GGCACCATGG CCACTCTGAG GTGCCAGATG AGCAAGGCTG CCCCTGTGGA GTGGAGGAAG 
GGGTCAGAGA CCCTGAGAGA TGGGGACAGA TACAGCCTGA GGCAGGATGG GGCCATGTGT 
GAGCTGCAGA TCCGTGGCCT GACCATAGAA GATTCTGGGG AGTACACATG TGTGTGTGGG 
CAGGAGAAGA CGTCAGCCAC ACTGAGTGTC AAGGCTCTGC CCCCCAGATT CATAGAAGAC 
TTGAGAAGCC AAGAGGCCAC AGAAGGCACC ATGGCCACTC TGAGGTGCCA GATGAGCAAG 
GCAGCCCCTG TGGAGTGGAG GAAGGGGTCT GAAACCCTGG GAGATGGGGG CAGATACAGC 
CTGAGGCAGA ATGGTGCTGT GTGTGAGCTG CAGATCCATG ACCTGGCTGT GGAAGACACT 
GGGGAGTACT CATGTGTGTG TGGGCAGGAG AAGACCTCAG CCACACTGAA TGTCAAGGCC 
CTGCCCCCCA GATTCATAGA AGACTTGAGA AGCCAAGAGG CCACAGAAGG CACCATGGCC 
ACTCTGAGGT GCCAGATGAG CAAGGCAGCC CCTGTGGAGT GGAGGAAGGG GTCTGAGACC 
CTGAGAGATG GGGGCAGATA CAGCCTGAGG CAGGATGGGG CTGTGTGTGA GCTGCAGATC 
CATGACCTGG ATGTGGAAGA TGCTGGCCAG TACTCGTGCG TGTGTGGGCA GGAGAAGACC 
TCAGCCGTGC TGACTGTAGA TGCACTGCCC CCCAAGTTTA CAGAGGGTCT GAAGAAGGAA 
GAGGCCACAG AAGGGACCAT GGTAACACTG AGGTGCCAGA TGAGCAAAGA AGCCACGGTG 
GAGTGGAGGA AGGGAGCAAA GACCCTCAGC GATGGGGGCA GATACAGCCT GAGGCAGGAT 
GGGGCCATGT GTGAGCTGCA GATCTGTGGC CTGGCTGTGG AAGACGCTGG GGAATACTCA 
TGTGTGTGTG GGCAGGAGAA GACCTCAGCC ACACTGAGTG TCAAGGCCCT GCCCCCCAGA 
TTCATAGAAG ACTTGAGAAG CCAAGAGGCC ACAGAAGGCA CCATGGCCAC TCTGAGGTGC 
CAGATGAGCA AGGCTGCCCC TGTGGAGTGG AGGAAGGGAT CCAAGACCCT GAGAGATGGG 
GACAGATACA GCCTGAGGCA GGATGGGGCC ATGTGTGAGC TGCAGATCTG TGACCTGGCT 
GTGGAAGACA CTGGGGACTA CTCATGTGTG TGTGGGCAGG AGAAGACCTC AGCCACACTG 
AGTGTCAAGG CTCCACAGGT GGTATTCCAG CAGCCACTGC AGAATCTGCA AGCAGAAGAA 
GGCTCCATGG CCAGCCTGCG GTGTGAGTTG TCAGTCCCCA ACGCTGCCAT GGTCTGGAGC 
AAGGGTGGTC TGGAGCTGCA GGGTGACACG CGCCGAGAGG CACGGCAGCA GGGGTGTGTG 
GCAGAGCTGT TGCTTAGGGA CCTGCGTCGC GAGGATGCGG GCGAGTACAG TTGCACCTGT 
GGCTCTCAGA CCACAAGCGC CACGCTCATG GTCACAGCTG CTCCTGTGCG GTTCCTCCGG 
GAACTGCAGG CCCAGGACGT AGATGAGGGG GCCACCGCAC GCCTGCGCTG TGAGCTGAGC 
CGGGAGGCTG TGAGCGTGGA GTGGCGCAAG GGCTCCTTGC AACTTTTTCC TTGTGCTAAG 
TATCAGATGG TGCAGGAGGG CACAACTGCG GAGCTGCTGG TCCATGGGGT GGAGCAGGAG 
GATGCAGGCG AATACACCTG CGATGCAGGC CACACGCAGA GCATTGCCAG GCTCTCTGTC 
CGAGCCCCCA AGCCCAAGTT CAAGACCGAC CTGCAAAGCA CAGAGCAGGA AGCAGGTGGC 
ACGGCACGGC TGTGTTGTCA ACTGAGCGAA GCTGAGCCAG GGACTCCAGT GCAGTGGCTC 
AAGGAGGGGG TGGAGCTGCA CGTCGGCTCC AAGTATGAGA TGCGGCGCCA AGGGGCTGTG 
TGCGAGCTGC TGATCCATGG GCTGGAGGCC AAGGACACTG GAGAATATGC CTGCCTGGTG 
GGTGGCCAGA AGACCTTGGC CTCCCTCAGA GTCAAAGAGC CTGAGGTGAC CATCGTGCGG 
GGACTCGTGG ACATGGAGGT GCAGGCCGAT GAGGATGTGG AGTTCACTTG CAAGGTGTCA 
CAGGCAGGAG CCACAGACGT GCAGTGGCAC CTCCAAGGTC TGCCACTGCA GAGCAATGAA 
GTGACAGAGG TGGCTGTCCT TGCGGACGGC TGTACCCATG TGCTCCAGTT AAAGGGTGTG 
ACACTGGAGG ATGCTGGTAC TGTCTCCTTC CACGTGGGCG GCCTTTCATC TTCTGCTCAG 
CTCACAGTCC GAGTCCCTGA GGTGACCGTT CTGGAGCCCC TGAAGGATGT GCAGCTCAGC 
GAGGGCCAGG ATGCCCACTT CCGGTGCCGA CTGTCCAGGG CCTCGGGCCA GGAGGCTCGC 
TGGGCTTTGG GAGGGGTTCC CTTGCAGTGC AACGAGATGA ACGACATCAC TGTGGAGCAG 
GGCACACTCT ACCTGCTCAC TCTGCACAAG GTGACCCTGG AGGATGCTGG GACCATCACT 
CTCCAAGTGG GCTCATGCTC CTCAGAGGCC CAGCTGAAGG TCACAGCCAA GAACACGGTG 
TTGCGTGGCC TGGAGAACGT GGATGCACTG GAGGGCGGTG AGGCTCTGTT CGAGTGCCAG 
CTGTCCCAGC CTGAAGTGGC CGCCCACACC TGGCTGCTGG ACGACGAGCC TGTGCACACG 
TCGGAGAAGG TGGAGGTGGT CTACTTTGAG AACGGACTGC GGCACCTGCT TCTACTCAAA 
AACCTGAAGC CACAGGACAG CTGCCGAGTG ACCTTCCTGG CAGGGGATGT GGTCACGTCC 
GCATTCCTCA CTGTGAGAGC TCTTCCTGAC CCCCCTGAAG ATGCTGAAGT GGTGGGGCGT 
AGTGACCATT CTGTGACCCT ATCCTGGGTG GCTCCCATGA GTGATGGAGG TGGGGGTCTA 
TGTGGTTATC GTGTGGAGAT GAAGGAGGCA TCCACAGGCC AGTGGCAGTT GTGCCATGAC 
TTGGTACCTG GTCCAGAGTG CGTGGTGGAC GACCTGGTCC CCGGGAAGAC CTACCGCTTC 
CGAGTGGCAG CTGTGGGTCC AGCAGGTGCT GGGGAGCCTG TACACTTGCC CCAGATGGTC 
AAGATAGCCC CAGCCCCGGC CCCGGCCCCG GCCCCTGCCC CAGCCCCTGC CCCAGAAACA 
CGGCAGGCAG TAGTTGGTGA AGACATCTGT CTGGAGTTGG AAGTGGCAGC TGATGGTGGC 
GAGGTCGTCT GGCACAAGGG AACAGAGCGC ATCCAGCCCG GAGGGCACTT TGAGGTCCTC 
TCTCGGGGTC AGCGGCAGAT GCTGGTGATC AAGGGCTTTA GGACCGAAGA CCAAGGGGAG 
TACCGCTGTG GTCCCATTCA GGGTCTGCCC TCCTCAGGAG CTGCCACGTT CAATGTGGTC 
ATGACCTCAG GCTCTGGGGA TGAGGTCCCG GCACAGCCTA GCCTGCCTCC CGAGGCAGCC 
CAGGAGGGTG ACCTGCATCT GCTTTGGGAG GCCCTTGCCC GGAAGCGCCG CATGAGTCGG 
GAGCCCACGC TGGACTCCAT CAGTGAGCTG CCTGAGGAAG ACAGCCGTGT GCAGCATCTG 
CGGCAGGAGG CAGAAGAGAC AGCTCCCGAC CTCTCTGAAG GCTACTCTAC AGCGGATGAG 
CTAGCACGCA CAGGAGAGGC CGACCTCTCA CACACCAGCT CTGACGATGA GTCTCGGGCT 
GGCACCCCTT CCCTAGTTAC CTACCTCAAG AAGGCCGGGG GTCCTGGGAT CTCACCCTTG 
GCCAGCAAGC ATGAGGCCCA GGTGACCACG TCTGTGAAGC CACAAAAGCA GCAGGAGCCA 
GTCGTGCCCA CGTGCCCACC GCCGGGAGAC TTGAGTGCAG CAGATTTGAT GGATCCATCC 
CTGGACAAGG CTGCTGTGAA GATTCAGGCT GCCTTTAAGG GTTACAAAGT GCGGAAGGAG 
ATGAAACAGC AGGAAGGGCC TGTGTTCTCA CGAACATTTG GGGACACAGA GGCACAGGTT 
GGGGATGTGC TGCGGCTAGA GTGTGTGCTG GCCACCAAGA CTGATATGCG GGCCTGCTGG 
TTGAAGGATG GCATCGAGTT AACAGATGGG CGCCATTACC ACATAGACCA GCTCAAGGAT 
GGTACCTGCT CTCTGCTGGT CACTGGCCTG GCCCCCACTG ACTCTGGCCG TTACACCTGT 
CAGGTGAGCA CCAAGTCTGG CCGTGTGAGC CACAGTGCCT GCGTGGTGGT CAGTGGGACA 
GAGAGCGAGG CCGAGAGCTC CTCTGGGGGC GAGCTGGATG ATGCTTTCCG CCGGGCAGCG 
AGACGCCTGC ACCGCCTCTT CCGCACCAAG AGCCCAGCTG AGCTTTCAGA GGAGGAACTC 
TTCCTCAGCG CTGATGAAGG CCCCGGGGAG CCAGAGGAGC CCGCAGACTG GCAAACATAC 
CGAGAGGATG AGAACTTTGT GTGCATCCGT TTTGAGTCCC TTGCAGAGGC CCGCCAGGCA 
GTCACCTGCT TCCGAAACAT GTTTGCCACT ATGGGCATCG GGGTGGAGAT CAGCCTAGGG 
GAGCAGGGAC CCCGGGGAGT GGAGATGCGC ATCGGCAAGG TGGCCCCTAC TGTCACCCCT 
GCAGTGCCGC TTGCAAAGAC ACCTGGCCTG CAGACTTCAG ATGCTGCCCC AGTGTTCCTG 
ACCGAGCTGC AGAACCAAGA TGTGCAGGAT GGATACCCCA TGAGCTTCGA CTGCGTGGTA 
ACGGGCCAGC CTGTGCCCAG TGTGCGCTGG TTCAAGGATG GGAAGCTGCT AGAAGAGGAT 
GACCACTATA TGATCAATGA GGACCAACAG GGGGGTCACC AGCTCATCAT CACAGCTGTG 
GTGCCGGCAG ACATGGGTGT CTACCGCTGC CTGGCGGAGA ACAGCATGGG CGTCTCCTCC 
ACCAAGGCTG AGCTTCGTGT GGAATTGACC AGCACAGACT ATGATACTGC TGCGGATGCT 
ACTGAGACCT CATCCTACTT CAGCGCCCAG GGATACCTGT CCAGTCGGGA GCAAGAGGGA 
ACGGAGTCAG ATGAGGGGCA GCTTCCCCAG GTGCTGGAGG AACTGAAAGA CCTCCAAGTG 
GCCCCCGGGA CACGCCTGGC CAAGTTCCAG CTCAAGGTGA AAGGCTATCC AGCTCCCAAA 
CTGTATTGGT TCAAAGATGG CCAGCCCCTG ACCACGTCTG ACCACATCCG CATGACTGAC 
AAGAAGACCC TGCACACCCT GGAGATTGTC TCGGTCACTC GGGAGGACAG CGGCCAGTAT 
GCAGCCTACA TCAGCAATGC TGTGGGTGCT GCCTATTCGT CAGCCCGGCT TCTGGTCCGA 
GGTCCCAGTG AACCAGAAGA GAAGCCAGCA TCAGATGTTC ATGAGAGGCT GGTGCCACCC 
CGAATCCTGG AGAAGTTCAC CCCCAAGAAA GTGAAGAGGG GCTCCAGCAT CACCTTTTCA 
GTGAAGGTGG AAGGACACCC GGCCCCCAGT GTGCATTGGC TCAAGGAGGA GGCAGAGAAG 
GGAGTCCTGT GGATTGGCCC TGACACCCCG GGCTACACCA TGGCCAGCTC TTCCAAGCAG 
CATAGCCTGG TCCTGCTGGA CGTAGGCCGA CAGCACCAGG GCACCTACAC ATGTATTGCT 
ACCAACCCTG CTGGCCAGGC GCTCTGCTCT GCCAGCCTGC ACATCTCTGG CTTGGCCAAA 
GAAGAAGAGC AGGAGAGAGT GAAGGAGGCC CTCATTTCCT CTTTCCTGCA AGGGACAAGC 
CAAGCTGTCT CAGCCCAGAT GTCAGAATCC GCAGGTTTTG CTGATCTTGT CGGGCAAAGC 
AAAGGCGAGT CTCTGGTGGC TGAGGAGGCC CACAGTCACC TGTCCCTTGC TGAGGTGGGC 
ACTGAAGAGT TCCTGCAGAA ACTCACCTCG CAGATCACGG AGATGGTATC GGCCAAGATC 
TCTCAGGCCA AACTCCAGGT GCCTGGAGGT GACAGCGATG AAGAGACCAA GACACCATCT 
GCTTCTCCTC GGCATGGCCG GTCACGTCCT TCCTCCAGTG TTCAAGAGTC CTCCTCAGAG 
TCAGAGGATG GGGACTCCCG TGGTGAGATC TTTGACATCT ATGTGGTCAC AGCTGACTAT 
CTGCCACTGG GAGCTGAGCA GGATGCCATC ATTCTGAGAG AAGGCCAGTA TGTGGAGGTC 
CTTGACTCTG CCCATCCCCT GCGCTGGCTT GTCCGGACCA AGCCCACCAA ATCCAGTCCT 
TCCAGGCAGG GCTGGGTGTC ACCTGCCTAC CTGGATAAGA GGCTCAAGCT GTCTCCTGAG 
TGGGGGCCCA CTGAGGCCCC CGAGTTCCCT GGCGAGGCTG TGTCTGAGGA TGAGTATAGA 
ACGAGGCTGA GCTCTGTCAT CCAGGAGTTG CTGAGTTCAG AGCAGGCTTT TGTGGGTGAG 
CTGCAGTTCT TGGAGAGCCA CCACATGAAG CACCTGGAGC GATCTCCCCG AGTACCCGCA 
GCTGTGGCCA GCCAGAAGAC AGTCATCTTT CGTAATGTGC AGGACATCAG CCATTTCCAC 
AGCAGCTTCT TGAAGGAGCT GCAGGGCTGT GGCACCGACG ATGATGTGGC CATGTGCTTC 
ATCAAGAACC AGGAGGCCTT TGAGAAGTAC CTCGAGTTCC TGGTGGGCCG CGTGCAAGCT 
GAATCAGTGG TTGTCAGCAC CCCAGTCCAG GAGTTCTACA AGAAATATGC AGAAGAGACA 
CTGTCAGCCA AGGACCCCAC ACAGCCACCC CCACCTCCTC TTCAGCACTA CCTGGAGCAG 
CCAGTGGAAC GGGTGCAGAA ATACCAGGCC TTGCTGAAGG AGCTAATCCG CAACAAGGCC 
CGCAACCGGC AGAACTGCGC GCTGCTGGAG CAGGCCTATG CTGTGGTGTC TGCCCTGCCT 
CAGCGCGCCG AGAACAAGCT GCACGTTTCT CTCATGGAGA ACTACCCAGG AACCCTGGAG 
GCCCTGGGAG AACCTATCCG CCAGGGCCAC TTCATAGTGT GGGAGGGGGC CCCAGGGGCC 
CGGATGCCTT GGAAGGGCCA CAACCGGCAC GTCTTCCTCT TCCGAAACTA CCTGGTGATC 
TGCAAGCCCC GAAGAGACTC TCGAACCGAC ACCTTCAGCT ATGTGTTCCG GAACATGATG 
AAGCTGAGTA GCATCGACCT GAATGACCAA GTAGAGGGGG ATGACCGCGC CTTTGAGGTG 
TGGCACGAAC GGGAAGACTC TGTGCGCAAG TACCTGCTGC AGGCACGGAC CGTCATCATC 
AAAAACTCCT GGGTGAAGGA GATCTGTGGC ATCCAGCAGC GCCTGGCCCA GCCTGTGTGG 
CGTCCCCCTG AGTTTGAAGA GGAACTAGCG GACTGCACAG CCGAGCTGGG TGAAACGGTC 
AAGCTAGCAT GCCGAGTGAC GGGCACACCT AAGCCTATTG TCAGCTGGTA CAAAGATGGG 
AAGCCAGTGG AGGTGGACCC ACACCACATC CTCATTGAAG ACCCTGACGG CTCCTGCACC 
CTCATCTTGG ACAACCTTAC TGGCATAGAC TCTGGCCAGT ACATGTGTTT TGCGGCCAGT 
GCTGCTGGCA ACGCCAGCAC CTTGGGGAAG ATTCTAGTAC AAGTGCCCCC ACGGTTTGTG 
AACAAGGTCC GGGCCACACC CTTTGTGGAG GGAGAGGATG CACAGATCAC CTGCACAGTG 
GAAGGAGCCC CGTACCCTCA GATCAGGTGG TACAAGGATG GTACCCTGCT AGCCCCGGGC 
AACAGGTACC GGATGTTGAA TGAACCCCGC AGTGGTGTGC TGGTGCTGGT GATCCAGGCG 
GCCAGCAAGG AGGACCTGGG ACACTATGAA TGTGAGTTGG TGAACCGGTT GGGCTCAACA 
CGTGGTGGTG GAGAACTATA CATGCAGAGC CCTGCACTGC GTGCCCGGGA CCAGCACCAC 
CGGGAACAGA TTGTGGCTGC CGTAGAAGGG GCCCCGTCCA TGCAGGTCAC TATTGAGGAT 
GTACAAGTAC AAGTAGGGGA CATGGCACAG TTTGATGCTG TCATTGAAGG CCACCCACCA 
CCCATAGTAA CCTGGTACAA GGGCAGCACC CAGCTGACGA GCAGTGCCCG GCTGAGCCAA 
CGGCAAGATG GAACGACATA CTCCTTGGTG TTGACTGACG TGGCTCCACA CGATGCCGGT 
GTCTACACAT GTGTTGCCAA TAATGCAGGT GGACAGGTGC TCTGCAAGGC AGAGCTGCTG 
GTCCATGGGG GGGACAAGCT AGATGCCGAA AATCAAGTCT ATCGGAGAAA ACTGCATTCC 
TTCTATGACG TTCAAGAAGA GATTGGGAGG GGTGTGTTTG GGTTTGTGAA AAGGGTTCAG 
CACAAAGGAA ACAAGATGTT CTGTGCCGCC AAGTTCATCC CCCTACGGAG TAAAACTCGG 
GCCCAGGCAT ACCAGGAACG AGACATCTTG GCTACACTCG GCCACCCACT GGTCACTGGG 
CTCCTGGATC AATTTGAGAC CCGGAAGACT CTCATCCTTA TCTTGGAACT GTGCTCGTCT 
GAGGAGCTGC TGGATCGGCT CTTCAAGAAG GGTGTAGTGA CTGAAGCCGA GGTCAAAGTC 
TATATCCAGC AGCTGGTGGA AGGCCTACAC TATTTGCACA GCCATGGTAT CCTCCACCTG 
GACATAAAGC CCCCCAACAT CCTGATGGTG CACCCAGCTC GGGAAGACAT CAAGATCTGT 
GACTTTGGCT TTGCCCAAAA GATCACCCCT TCAGAGCCAC AGTACAGCAA GTATGGCTCA 
CCCGAATTCG TGTCCCCAGA GATCATTGAG CAGAATCCTG TGAGCGAGGG CTCAGACATC 
TGGGCCATGG GCGTCATCTC CTACCTCAGC CTCACCTGCT CATCCCCATT TGCTGGAGAG 
AGTGACCGCG CCACCTTGCT CAATGTTTTG GAGGGGCGGG TCTCCTGGAG CAGTCCCACG 
GCTGCTCATC TGAGTGAGGA CGCCAAGGAC TTCATCAAGG CCACGCTGCA AAGGACCCCC 
AGGGCCAGGC CTAGTACTTC CCAGTGCCTT GCCCACCCCT GGTTCCTGAA ATCCATGCCT 
GCTGAGGAGG CCCACTTCAT CAACACCAAA CAGCTCAAGT TCCTTCTTGC TCGAAGTCGC 
TGGCAGCGTT CCTTGATGAG CTACAAGTCT ATCCTGGTGA TGCGCTCCAT CCCTGAGCTG 
CTTCAGGGTC CCCCAGACAG TCCATCTCTA GGAGTGGCCC GGCACCTACG AGGGGAAGCC 
AGTGGCGCCT CTAGCTCATC ATCTTCCTCA GACAACGAGC TTGCCCCATT TGCCAGGGCT 
AAGTCGCTGC CACCTTCTCC TGTGACTCAC TCGCCACTGC TGCACCCTCG GGGCTTTCTG 
CGGCCTTCGG CCAGCCTCCC AGAGGAGACA GAGGCCAGCA TGCCCACTGC TGATGCGGCC 
GTGCCAGCGT CCCCACAGAG TGCTGGGCCT CCGGCAAGCC CAGGTTGTGT GCCCCGGCAC 
AGCGTCATCA GCAGCCTGTT CTACCAGCAA GCTGGCGAGG GTGCAGAGCG TGGGAACAAA 
ACATCGGGTG CCAAGAGGCA CCCTGCGCGG AGGCGGCACC TGCTAAAGGG TGGGTACATT 
GCAAGGGCCT TACCCGGTCT GCGTGAGCCC CTCATGGAGT ACAGCTTGTT GGAGGAAGAG 
GCGGCTAGGG AAGAGCAGGC CTCTCTGATG ACCAAGACAC CCTCCTTTGA GACTGCCCTG 
CGACTACCTA GTTCCAGTGT CAGAGAGGTC CCAGGCCGAA GCCACTCCCT GGACAACCCA 
CCAGTCACGA CTGGCCCCTC TCCTGAGGCA TGCAAGGAAC AACTCCTGTT CCCACCCTCC 
ACGGGGTTGA CTCATGAAAC CACTGCCAAG GACAGGGGGC ACAAAGAGGG GTTCTTGCAG 
GAGTCTGTCC CCTTTCCACC TATGAGTGGT GACTCGAGGC CTGGGAAGCA AGAGGGATCA 
TCCCAGGACA GTTGTAGAGG GAAACCAGCC TCTTCCTGTC ACTCTGAGCT GGGTTCTGGT 
TCCCAGGAGG GCTGTGGCCC TCCATCATCT CAATCGCTTG GCTCCTTACC TCCACAGTCA 
TTGAAGAAGG AGCTCTCAAC GTCCTGTGGC CCACTCTTTT CAGAACAGCC TCAGGCAGCC 
CCATTCCCAA CTCAAGTAAG CCCCCTTCTG GGTTCTGAGA AGGAACCTCA GGATGGCTCT 
CTATCTGAAG GGCCAGTTCC AGTTCCCTCC AGTTCTCCAG GGTCAGCTTC CCAAGTAGAT 
GCATCCTTGG ATACTGAAGG CTTGTCTGAA GCTGGGGACA CATGTGACTT CACGCCTCCT 
CCACAGCGGC CTCAGGAGCA GGCCACCACC CGGAAGTTCT CTCTGGAGTC CCGTGGGGGC 
TATGCAGGGG TGGCAGGCTA TGGTACTTTT GCCTTTGGCG GGGATGCAGG GGGGATGCTA 
GGGCAGGGTC CTCTCTGGGC CAGGATGGCC TGGGCTGTGT CCCAGTCCTC AGAAGAGCAG 
GATGAAGCTG CGACTGAGAG CCCTCAACCT CTGGAGAGCT TGGGGCCCAT TGCTGAGGCC 
AGTGGGGTTC CCCTAAGGAC CTCTCCAAGC CTCACCCCTT GGGAGGAAGT TGAGCAGGTT 
TCCCTGGTGC AGATCCGGGA TCTGTCTGGT GATGCGGAAG CAGCTGACAC TATCTCCTTG 
GACATTTCTG AGGTCGATCC TGCCTACCTC AACCTCTCGG ATCTATATGA CATCAAATAT 
CTCCCATTTG AGTTCATGAT CTTCAGAAGG GTCCCCAAAC CTATAGAGCA GCCAGAGTCA 
CCTGGCTCAG AAACCGAAGC TGGGCAAGGG CTGGCAGATT TCCTGGAGGA GGCCGCGTGG 
CCCTGGCCAG GCGAGCTGGG ACTGCGTGCT GGTCTGGAGA TTACAGAGGA GCCGGAGGAG 
CCAGGGGACC TGGAAGCACT GCTGGGCGAG GCTGCTGTGG GCAGGAAGCG CAAGTGGTCC 
CCCTCCCGGG GCCTCTTCCA ATTCCCTGGG AGGTGCCTGT CAGGGGAGGA GCCTGTGGAG 
CTTGGGCTGC GCCAGAGGGT GAAGGCTTCC ATGGCTCACA TCTCCAGGAT CCTCAAGGGC 
AGGCCGGAAG GTCCTGAGAG GGAAGGGCCT CCCAGAAAGA AGGCAGGCCT AGCTTCTTTC 
CGGCTGTCAG GCCTGAAGGG CAGGGACCAA GAACTCTCAG ACGAGGCTGT GGTCCTGGGC 
CAATCAGTGA CACTGGCCTG CCAGGTGTTG GCCCAGCCAA CTGCCCAGGC TACCTGGAGC 
AAAGATGGGG TCCTCCTGGA GAGCAGCGGC CACCTCCTCA TCTCCTCCAC CCTGAAGAAC 
TTCCAGCTGC TGACCATCCT GGTGGTGAAA GAGGAGGATC TGGGCACATA TACCTGCTGT 
GTGAGCAACC CGCTGGGGAC AGCAGTCACC ACAGGTGTCC TCCGGAAAGC AGAGCGCCCT 
TCATCTTCTC CACGCCCTGA GGTGGGGGAA CTATACAAGG ATGCGGTGCT GCTGGTCTGG 
AAGCCTGTGG AATCCTGTGG CCCGGTGACC TACATTGTGC AGTGCTGTAT AGAAGGAGGC 
AGCTGGACAA CCCTGGCTTC AGACATCTCT GACTGCTGCT ACCTCACTGG CAAGCTATCG 
AGGGGTGGCA TGTATATCTT CCGGACAGCA TGTGTCAGCA AAGCAGGAAT GGGCCCCTAC 
AGCAGCCCCT CAGAACAGGT CCTCCTCGGA GGACCCAACC ACCTGGCCTC TGAGGAGGAA 
AGCAGCCGGG GGAGGCCAGC CCAGCTTCTC CCCAGCACAA AGACCTTTGC CTTCCAGATG 
CAGATCCGGA GGGGCCGCTT CAGTGTGGTG CGGCAGTGCA GGGAGAAGGC AAGTGGGCGG 
GCCCTAGCTG CTAAGATCGT TCCCTACCAA CCTGAGGACA AGACAGCTGT ACTAAGAGAA 
TACGAGGCAC TTAAGAGACT GCACCACCCA CATCTGGCCC AACTCCATGC CGCCTACCTC 
AGTCCCCGGC ACCTGGTGCT CATCCTGGAG CTGTGCTCTG GCCCTGAGCT GCTACCCTCT 
TTGGCAGAGA GGGAATCCTA CTCAGAGTCT GATGTGAAGG ACTACCTGTG GCAGATGCTG 
AGTGCCACCC AGTACCTGCA TGCCCAACAC ATCCTGCACC TGGACCTGAG GTCCGAGAAC 
ATGATGGTCA CTGAGTACAA CCTGCTTAAG GTTATAGACC TGGGAAATGC CCAGAGTCTC 
GACCAAGAGA AGGTCCCAGC CCCTGAGAAC TTCAAAGACT ACCTGGAGAC CATGGCTCCA 
GAACTCCTGG AAGGTCAAGG GGCTGTTCCA CAGACAGACA TTTGGGCTAT TGGTGTAACA 
GCCTTCATTA TGCTGAGTGG CGAGTACCCA GAGAGCAGCG AGGGGACTCG CGACCTGCAG 
AAAGGCTTGC GCAAGGGACT CATTCGGTTG AGTCGCTGCT ATGCAGGATT ATCAGGAGGA 
GCCGTAGCCT TCCTGCAGAG TTCATTATGT GCTCAACCCT GGGGCCGCCC GTGCGCTTCC 
ACCTGCTTGC AATGCGGATG GCTGACAGAG GAGGGCCCCA CCGGCTCCCG GCCCACGCCC 
GTAACCTTCC CCACCGTGCG GTTGCGCGCC TTTGTGCGCG AGCGCGAGAA GCGGCGTGCG 
CTCCTCTACA AGAAGCATAA CCTGGCCCAG GTGCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001164983.2
CDS	1..24099
Translation	MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYRRKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSKTRAQAYQERDILATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSKYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHLRGEASGASSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEETEASMPTADAAVPASPQSAGPPASPGCVPRHSVISSLFYQQAGEGAERGNKTSGAKRHPARRRHLLKGGYIARALPGLREPLMEYSLLEEEAAREEQASLMTKTPSFETALRLPSSSVREVPGRSHSLDNPPVTTGPSPEACKEQLLFPPSTGLTHETTAKDRGHKEGFLQESVPFPPMSGDSRPGKQEGSSQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQAAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCDFTPPPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGSETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQFPGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPPRKKAGLASFRLSGLKGRDQELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR

Target ORF information:

RefSeq Version	NM_001171512.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001171512.2

ORF Insert Sequence:

ATGGACCACT CCTTCAGCGG AGCACCCCGC TTCCTGACGC GGCCAAAGGC CTTTGTGGTA 
TCTGTTGGCA AGGATGCCAC GCTGAGCTGC CAGATCGTGG GCAACCCCAC GCCACACGTG 
AGCTGGGAGA AGGACCGGCA GCCAGTAGAG GCAGGAGCGC GCTTCCGCCT GGCCCAGGAC 
GGGGATGTGT ACCGCCTCAC AATTCTCGAT CTGGCGCTAG GTGACAGCGG GCAGTATGTG 
TGTCGCGCGA GGAACGCCAT AGGGGAGGCC TTCGCCGCCG TCGGCCTGCG AGTGGACTCG 
GAGGGCACGT GTGCCGAGCA GGCGCCCCAC TTTCTGCTGC GGCCCACATC CATTCGCGTG 
CGCGAGGGCG CAGACGCCAC CTTCCGATGT CGCGTTGGAG GCTCACCACA ACCTGCTGTG 
AGCTGGTCCA AAGATGGGCG GCGCCTGGGC CCACCCGATG CCCCCCATGT GCGTGTGGAA 
GAACACGGGG AGTCGAGCGC GCTTCGCATC CGTTCGGCAA GGCCTCGCGA TGGTGGCACC 
TACGAAGTCC GAGCAGAAAA TCCGCTGGGC TCTGCCAGCG CTGCCGCCGC TCTGGTGGTG 
GACTCGGACG CCGAGGTTGC CGGACCACCC GGCACCTCCA CCGCCACGCT CCTGGCGCAC 
CTGCAGCAGC GGCGGGAGGC CATGCGCGCA GAGGGCATAC CCCCTTCTCC ACCCGGCGCT 
GGCACGCGCA CCTGCACGGT GACCGAAGGC AAACACGCGC GCCTCAGCTG TTTTGTGACC 
GGCGAGCCCA AGCCCGAGAC AGTGTGGAAG AAGGACGGGC AGCTGGTGAC CGAGGGCCGG 
CGACACGTAG TGTATGAGGA CGAGCAAGAG AACTTCGTCC TTAAGATTCT TTTCTGCAAG 
CAGTCCGACC GCGGCCTCTA CACCTGCACA GCGTCCAACC TCGTGGGCCA GACCTACAGC 
TCGGTGCTGG TGGTCGTGAG AGAGCCGACG GTGCCCTTCA AGAAGCGGCT GCAGGACCTG 
GAGGTACGAG AGAAAGAGTC TGCTACATTC CAGTGCGAGG TGGCTCAGCC AGCTACCGAG 
GCGGCGTGGT TCAAGGAGGA GACCCGGCTA TGGGCCAGCG CCAAGTACGA CATCGAGGAG 
GAGGGCACCG AGCGCCGGCT GACCGTGCGC AACGTCTCGG CAGACGACGA CGCTGTGTAC 
ATCTGCGAGA CCACAGAGGG CAGCCGCACG GTGGCAGAGC TCTCTGTTCA AGGAAACTTG 
ACCAGAAAGC TGCCTCGGAA GACAGCAGTG CGCACTGGAG ACACAGCCAT CTTTTGGGTG 
GAGCTGGCTG TCCCCGAAGG CCCTGTCCGG TGGCTACGGA ACCAGGAGGA GATGGTGGCA 
GGGGGTCGGG TTGCCATCAC TGCAGAAGGC ACGTGCCACA CACTGACCAT CTTCCAGTGC 
ACCTTGGAGG ACATGGGTGA GGTGGCCTTT GTGTCTGGTG GCTGCCGGAC GACCACCCAG 
TTCTGTGTAT CAGCGCCCAG GAGGCCACCC CTGTACCCTC CTGCTGACCC TGTTGTAAAG 
GCCAAGACAG AGAGTTCTGT GACCCTCAGC TGGTCCGCAC CACCCCATGG GGACCGCCCT 
GTCACTATTG ATGGCTATGT GTTGGAGAAG AGGAAGCTGG GTGCCTATGC CTGGAGCAGG 
TGTCACGAAG CTGGATGGCT GGCCACAACT GAGTTTACCA TCACTGGTGT GGCTGAGGAG 
GGGGATTTCC AGTTCCGAGT GTCAGCCATC AATCACTTTG GCCAGGGTCC TTACCTTGAA 
TTTCCAGGGA CCATGCACTT GGTCCCCATG CTGGCTGTAA AGACACCTCT GAAGGCGGTG 
GAGGCAGTGG AGGGTGGTGA GGTCACTTTC TCCGTGGACC TCACGGTGGC CTCTTCGGGC 
GAATGGTTCC TGGATGGGGA GGCCTTGAAA GCGAGCAGTA TATACGTGAT CCGTTGTGAC 
CGCACCCGGC ATATGCTCAC CATCAGAGAG GTGCCCGCCA GATTGCATGG GGCACAGCTG 
AAGTTTGTGG CTAATGGCAT TGAAACTAGC ATCCAAATGG TGGTCCGAGC GGCTCTGGGG 
CTGCCCAGCA GTAAGCTTCC TGCTGCGGCT GCCCGGGAGG TGCTGGCCCA GTTGCACGAG 
GAGGCACAGC TGCTGGCTGA GCTGTCGGAC CAGGCTGCTG CTGTGACTTG GCTGAAGGAT 
GGTCGTGAGC TGTCCCTAGG GCCCAAGTAT GAGATGCAGG TGTCAGCTGG GAGGCGAGCA 
CTGCTGGTGC GGGACGTGGC ACAGGATGAC GCTGGCCTCT ATGAGTGTGT CAGTCGTGGG 
AGCCGCACTG CCTACCAGCT GTTGGTGCAA GACATAACAG ATGGCTACCG TGACTGGGGC 
CCAGCAGGAC CTCAGAAGCA CATGTGCAAG TGTGCTGGGG CAAAGATAGC GAGATACTTG 
GGTTCCTCTT GCTACCGCTT CTTGCAGTAT GACAAGGGGG TATGGCATTG GCTGGAGGCA 
GCTTTGGACA CCAGGCAGGG CAAGGGTACC TCCTCCTGCT CCCTGCATGA AAAACCCAAG 
CTGGTATTTG CCAAGGGGCA GCAGGCACAC AGTGAGGTGA AGGCAGAGGC GGGGGCCAGC 
GCCACACTGA GCTGCGAGGT GGCCCAGGCC CAGACTGAGG TGACATGGTT CAAGGACGGG 
AAGAAGCTGA GCTCCAGCTC GAAGGTGCGC ATGGAGGCCT CGGGCTGCTC CAGGAGGCTG 
GTGGTGCAGC AGGCGGGCAA GGCGGATGCT GGGGAGTACA GCTGCGAGGC CGGGGGACAG 
AAGCTCTCCT TCCGCCTGGA CGTGGCAGAG CCCAAGATGG TGTTTGCCAA GGAGCAGCAG 
GCACGCAGCG AGGTGAAGGC CGAGGCGGGG GCCAGCGCCA CACTGAGCTG CGAGGTGGCC 
CAGGCTCAGA CTGAGGTGAC ATGGTTCAAG GACGGGAAGA AGCTGAGCTC CAGCTCGAAG 
GTGCGCATGG AGGCCTCGGG CTGCTCCAGG AGGCTGGTGG TGCAGCAGGC GGGCAAGGCA 
GATGCTGGGG AGTACAGCTG CGAGGCCGGG GGACAGAAGC TCTCCTTCCG CCTGGACGTC 
ACAGAGCCCA AGCTGGTGTT TGCCAAGGAG CAGCAGGCAC GCAGTGAGGT GAAGGCAGAG 
GTGGGGAACA GTGCCACACT GAGCTGCGAG GTGGCCCAGG CCCAGACTGA GGTGACATGG 
TTCAAGGACG GGAAGAAGCT GAGCTCCAGC TCGAAGGTGC GCATGGAGGC CTCGGGCTGC 
TCCAGGAGGC TGGTGGTGCA GCAGGCGGGC AAGGCGGATG CTGGGGAGTA CAGCTGCGAG 
GCCGGGGGGC AGAAACTCTC CTTCCGCCTG GACGTGGCAG AACCCAAGCT GGTGTTTGCC 
AAGGAGCAGC AGGCACGAAG TGAGGTGAAG GCAGAGGCAG GGAACAGTGC CACACTGAGC 
TGTGAGGTGG CCCAGGCACA GACTGAGGTG ACATGGTTCA AGGACGGGAA GAAGCTGAGC 
TCCAGCTCAA AGGTGCGCAT GGAGGCCTCG GGCTGCTCCA GGAGGCTGGT GGTGCAGCAG 
GCGGGCAAGG CGGATGCTGG GGAGTACAGC TGCGAGGCCG GGGGACAGAA GCTCTCATTC 
CATCTGGACG TCACAGAACC CAAGCTGGTG TTTGCCAAGG AGCAGCAGGC ACACAGTGAG 
GTGAAGGCAG AGGCGGGGGC CAGTGCCACC CTGAGCTGCG AGGTGGCCCA GGCCCAGACT 
GAGGTGACAT GGTTCAAGGA CGGAAAGAAG CTGAGCTCCA GCTCAAAGGT GCGCATGGAG 
GCCTCGGGCT GCTCCAGGAG GCTGGTGGTG CAGCAGGCGG GCAAGGCGGA TGCTGGGGAG 
TACAGCTGCG AGGCCGAGGG ACAGAAGCTC TCCTTCCGCC TGGACGTGGC AGAGCCCAAG 
CTGGTGTTTG CCAAGGAGCA GCAGGCACGC AGCGAGGTGA AGGCAGAGGC TGGGGCCAGT 
GCCACACTGA GCTGTGAGGT GGCCCAGGCC CAGACTGAGG TGACATGGTT CAAGGACGGG 
AAGAAGCTGA GCTCCAGCTC GAAGGTGCGA GTGGAGGCCT CGGGCTGCTC CAGGAGGCTG 
GTGGTGCAGC AGGCGGGCAA GGCGGATGCT GGGGAGTACA GCTGCGAGGC CGGGGGCCAG 
AAGCTCTCCT TCCGCCTGGA CGTCGCAGAG CCCAAGCTGG TGTTTGCCAA GGAACAGCAG 
GCAAACAGCG AGGTGAAGGC CGAGGCGGGG GCCAGCGCCA CACTGAGCTG CGAGGTGGCC 
CAGGCCCAGA CTGAGGTGAC ATGGTTCAAG GACGGGAAGA AGCTGAGCTC CAGCTCGAAG 
GTGCGCGTGG AGGCCTCGGG CTGCTCCAGG AGGCTGGTGG TGCAGCAGGC GGGCAAGGCG 
GATGCTGGGG AGTACAGCTG CGAGGCCGGG GGGCAGAAGC TTTCCTTCCG CCTGGACGTG 
GCAGAGCCCA AGCTGGCGTT TGCCAAGGAG CAGCAGGCAC ACAGCGAAGT GAAGGCAGAG 
GCGGGGGCCA GCGCCACACT GAGCTGCGAG GTGGCCCAGG CCCAGACTGA GGTGACATGG 
TTCAAGGATG GGAAGAAGCT GAGCTCCAGC TCGAAGGTGC GCGTGGAGGC CTCGGGCTGC 
TCCAGGAGGC TGGTGGTGCA GCAGGCGGGC AAGGCGGATG CTGGGGAGTA CAGCTGCGAG 
GCCGGGGGAC AGAAGCTCTC ATTCCGCCTG GACGTGGCAG AGCCCAAGCT GGCGTTTGCC 
AAGGAGCAGC AGGCACACAG CGAGGTGAAG GCAGAGGCGG GGGCCAGCGC CACACTGAGC 
TGTGAGGTGG CCCAGGCCCA GACTGAGGTG ACATGGTTCA AGGACGGGAA GAAGCTGAGC 
TCCAGCTCGA AGGTGCGCGT GGAGGCCTCG GGCTGCTCCA GGAGGCTGGT GGTGCAGCAG 
GCGGGCAAGG CGGATGCTGG GGAGTACAGC TGCGAGGCCG GGGGTCAGAA GCTCTCCTTC 
CGCCTGGACG TGGCAGAGCC TAAGCTGGCG TTTGCCAAGG AACAGCAGGC ACACAGCGAG 
GTGAAGGCAG AGGCGGGGGC CAGTGCCACA CTGAGCTGCG AGGTGGCCCA GGCCCAGACT 
GAGGTGACAT GGTTCAAGGA CGGGAAGAAG CTGAGCTCCA GCTCGAAGGT GCGCGTGGAG 
GCCTCGGGCT GCTCCAGGAG GCTGGTGGTG CAGCAGGCGG GCAAGGCGGA TGCTGGGGAG 
TACAGCTGCG AGGCCGGGGG ACAGAAGCTC TTCTTCCGCC TGGATGTGGC AGAGCCCAAG 
CTGGTGTTTG CCAAGGAGCA GCAGGCACAC AGTGAGGTGA AGGCCGAGGC GGGGGCCAGC 
GCCACCCTGA GCTGCGAGGT GGCCCAGGCC CAGACTGAGG TGACATGGTT CAAGGACGGG 
AAGAAGCTGA GCTCCAGCTC GAAGGTGCGC GTGGAGGCCT CGGGCTGCTC CAGGAGGCTG 
GTGGTGCAGC AGGTGGGCAA GGCGGATGCT GGGGAGTACA GCTGCGAGGC CAGGGGACAG 
AAGCTCTCCT TCCGCCTGGA CGTGGCAGAG GCCGAATCCC AGATTCCGGA GAGACCCAGC 
CGCAGGGAAC CTCTGGTTGT CAAGGAACAT GAGACCATTA TCCTGACTGC CACAATAGCT 
GCACCCTCTG TGGCTGCTGT GACCTGGCTC AAAGATGGAG TGGAGATCCG CCGCAGTAAG 
CGGCATGAGG CCACCAGTCT GGGTGATACC CATACCCTGA CCGTGAGAGG CGCACAGGTC 
CTGGACAGTG CCATCTACAG CTGCCGTGTT GGCAAGGAAG GTCAGGACTT CCCGGTGCAG 
GTAGAAGAGG TGGCCGCCAA GTTCTCCAAA CCCCTGGAGC CCGTCGAAGG GGAGCTGGGT 
GGCACCGTGA TGCTGGTTTG TGAGCTGAGC CCGGAGCAGG CTGAGGTTGT GTGGCGCTGT 
GGGAACACAC AGCTGCGGCC AGGCAAGCGC TTCCAGATGA CATCAGAGGG GCCTAGGCGC 
ACGCTGACCG TGTCTGGCCT TCGAGAGGAT GACGCAGAGG AGTATGTGTG TGAGAGCCGG 
GATGACCGCA CCAGCGCACG GCTCACTGTT AAAGTTCCCC GAGTGGTCAA GTTTACGTCT 
GGATTGAGTG CCATGGTCGC AGAGGAGGGC CAAGAGGCCA CCTTTCAGTG TGTCGTGTCC 
CCCAGCGATG CAGGGGTCAC ATGGTACAAG GACGGGATGC AGCTGCAGCC TAGCGAGAAG 
TTTGTTATGG TAGAGAGTGG GGCCAGCCGC AGCTTGACTA TCTTGGGCCT GACCCTGGAG 
GATGCCGGTC AAGTCACAGT GGAGGCTGAG GGGGCTTCAT CTTCTGCTGC CCTCCGGGTC 
CGAGAGGCAC CGGTCCTCTT CAAAAAGAAG CTGGAGCCAC AGACAGTGGA GGAGAGGACC 
TCTGTGACAT TGGAGGTGGA GCTGACGCGG CCCTGGCCCG AGGTGAAGTG GACACGGAAT 
GCTGCCGTCC TGACACCCAG CGAGAACGTG GAGATCCGCG CTGAGGGTGC TCGGCACTGT 
CTGGTGCTGC GCAGCGTGGG CTTTGCTGAC CGCGGCTTCT TTGGCTGTGA GACACCAGAT 
GATAAGACTC AGGCCAAGCT CAATGTAGAA ATGCGGCAGG TCCGGCTGGT TCGCGGTCTG 
CAGGAGGTGG AGGCTAAGGA ACAGGGCACG GCCTCGATGG ATGTGGAGCT GTCCCATGCC 
GAGGTGGAGG GCAGCTGGAC CCGAGATGGC CTGCGACTTC AGCCTGGACC CAAATGCCAC 
CTGGCCGTAC AAGGCCCTGT CCACATCCTC ACACTCTCGG CGCTGCAGCC ACAGGACAGT 
GGGCTGGTGG CCTTCAGGGC CGAGGGCGTG CACACGTCTG CGAGGCTCAT AGTCACTGAG 
TTGCCCGTGA GCTTCACCAG AGTACTACAG GATGTGGTGG CCACGCAGAA GGAGAAGGTC 
ACCCTGGAGT GTGAGCTGTC GAGGCCTGTG GATGTGCGCT GGCTGAAGGA TGGTGTGGAG 
CTGCGGGCAG GCAAGGCCAT AGGCATAGTG GCCCAGGGAA CCTGCAGGAG TCTCGTTATC 
TACCGCTGTG AGACTGGGGA CCAGGGTGTC TATGTATGTG ATGCTCTTGA TGCTCAGACC 
TCTGCCTCTC TGAGGGTGCA AGGGAGGACA TACACGCTTA TCTTCCGGAG GGTACTGGCA 
GAGGATGCAG GGGAGGTCAA GTTTGTAGCT GAGAACGCAG AATCAAGAGC TCACCTCCGA 
GTGAAAGAAC TGCCCGTGAC CCTCCTGCGC CCACTGAGGG ACAAGATTGC CATGGAAAAA 
CACCGTGGAG TGCTGGAGTG CCAGGTGTCC CGGGCTAGTG CCCAGGTGCG GTGGTTCAAG 
GGCGGAGTCG AGCTGCAGTC TGGGCCCAAG TACGAGGTGG TCAGTGACGG CCTTTACCGC 
AAGCTGGTCA TTAATGACGT GCAGCCTGAG GATGAAGATA CGTACACCTG TGACGCTGGC 
AACGTCAAGA CCAGTGCCCA GTTCTTTGTG GAAGAGCAAT CCATCACTAT TGTGCGGGGA 
CTGAAGGACA TGACAGTGAT GGAGCCTGCC CCTGCCTGGT TTGAATGTGA GACATCCATC 
CCTTCCGTGA GGCCACCCAA GTGGCTCCTT GGTAAGACTG TGCTCCAGGC AGGGGGGAAC 
GTGGGACTGG AGCAAGACGG CACCGTGCAC CGGCTGACAC TGCACAAGAC CTGCTCTACC 
ATGACCGGGC CTGTGCACTT CACTATCGGC AAGTCCCGCT CCTCTGCCCA GCTGGTTGTC 
TCAGACATTC CTGTGGTACT GACACGGCCT CTGGAGCCCA AAGCAGGGCG TGAACTGCAG 
TCAGTAGTCC TGTCCTGTGA CTTCAGGCCA GCCCCCAAGG CTGTGCAGTG GTACAAGGAT 
GACACACCCC TGTCCCCGTC AGAAAAGTTC AAGATGGCGC TGGAGGGCCA GATGGCAGAG 
CTGCGCATAC TCCGGCTCAC GCCAGCTGAT GCTGGGGTCT ACCGGTGCCA GGCGGGTAGC 
GCCCAGAGCA GTGCTGAGGT TACTGTGGAA GCTCGGGAGG TGACAGTGAT TCAGCCACTG 
CAGGATGCAG AAGCCATGGA GGAAGGCCGG GTCTGCTTCT CCTGCGAGCT GTCCCATAAG 
GATGAAGATA TCGAATGGTC ACTCAATGGT ACACCCCTGT ACAATGACAG CTTCCATGAG 
ATCAGCCATG AGGGCTGTCT CCACACCCTG GTGCTGAAGA GTGTCCGGCA GGCTGACACA 
GGCACCGTGT GCGCCACCTC CCCCAAGGTG TCCGTTTCCG CCCGGCTGGT GGTTAAAGGC 
AAGCCAGTGG TGTTCCTGAA AGCACTGGAT GACGTATCTG CAGAAGAGCG TGGCACGCTG 
ACCCTGCAAT GCGAGGTCTC CGACCCCGAG GCACGCGTGG TTTGGCGCAA AGATGGTGTG 
GAGCTTGGTC CCAGCGACAA GTATGATTTC CTACATAAGG CAGGTGCCCG GGGCCTTACG 
GTCCATGACC TGAGCCATGA GGATGCTGGA CTGTACACCT GCCAGGTGGG CAGTAAGGAG 
ACCCAGTCCA AGGTCAGCGT ACATGATCTT CACGTGGGCA TCACCAAGAG GTTAAAGACA 
GTGGAGGTGC TGGAGGGAGA GAGCTGCAGC TTTGAGTGTG TCCTTTCCCA CGAGAGTCCC 
AGTGACCCAG CAGTGTGGAC GGTCGGTGGG AAGACAGTGG GTGGTTCTGG CCACTTTCAC 
GCCGTTCGGC AGGGCCGCAA ATACACCCTG ACAGTCAAAG ATGCTGCACT CAGTGATGCA 
GGAGAGGTGG TCTTCTCGGT GCTGGGCCTC ACTTCCAAGG CCTCGCTCAT CATCAGAGAG 
AGGCCAGTGG ACATCACCAA GCCCCTGGAG GACCAGCGGA CGACGCTTGG GGAAGATGTA 
ATGCTAAGCT GTGAGCTGTC CAGGGCAGGC ACCTCTGTGC GCTGGCTGAA AGACGGGAAG 
GCCATCAGGA AGAGCCAGAA GTATGACCTG CTCAGTGAAG GCACGCGGGC TGTGTTGGTT 
GTCCGCAAGG CCTCACTCAA GGATTCAGGG GAATACACCT GCGAGACAGA AGCTTCGAAA 
AGCACTGCCA AGCTCTGTGT GGAAGAAAAG GCAAACCGGT TCACGGAGGA GCTGGCTGAC 
CTGCAGGTGG AAGAGAAGGG CAGAGCTGTG TTCACATGCA AGACAGAGCA CCCAGCATCT 
GTCGTGACCT GGCGCAAAGG CCTCCTGGAG CTGCGCGCCT CAGGGAAGCA TGTCCCCAGT 
CAGGAAGGCT TGACCCTGAA GCTCACCATC AACGCCCTGG AGAGGACAGA CAGTGACACT 
TACACCTGTG ACATCGGCCA AGCCCGGACC CAGGCACGGC TCCTCGTCCA CGGCCAGAAA 
GTGCGCGTTA TTGAGGACCT AGAGGACACT GCTGTCCAGG AGGGCTCCTC TGCTAAGTTT 
TGCTGCCGCA TCGCTCCTGC TGACTACGGC CCCGTGCACT GGTTCCTGGA TAAGACCCCC 
TTGCACAGCA ATGAGCTGAA TGAGATCACT GTCCAGCCTG GAGGCTATCA CGTGCTCACC 
CTGCGGCAGC TGGCACTCAA GGACTCAGGC ACTGTCTACT TTGAGGCGGG TGACCAGCGA 
ACCTCAGCTG CCCTGCGGGT GACTGAGAAG CCGAGCATCT TCTCTCGGCC ACTCACAGAC 
GTCACAGTCA CAGAAGGCGA GGACCTGACT CTGGTCTGTG AAACCACCAC TGTGGATAGC 
TCTGTGCGCT GGACCAAAGA TGGGAAGACA CTGAGGCCGT CTGCACGATG CCAGCTGAGC 
CATGAAGGCT GTCAGGCCCA GCTGCTCATC ACTGCCACCA CCCCACAAGA TGGTGGGCGG 
TACAAATGTG AGATTGGTGG AGCCTCCAGC AGCTCCATTG TCAGGGTCCA TGCTCTGCCA 
GTGCGGTTCA GGGAGTCCCT GAAGGACGTG GAGGTACCAG AGGGCAAGGC CGCCACACTG 
CGCTGTGTGC TGTCATCCGT GGCTGCACCT GTGGAGTGGC GTCATGGAGA TGATGTCCTG 
AAATCCAGCA ACAAGTATAG CCTGCGCCAA GAGGGTGCTG TGCTGGAATT GGTCATCCGA 
GACCTGCAGC CCCAGGACAG TGGGCAATAC TCATGCTCCT TTGGGGACCA GACAACTTCA 
GCCACACTCA CAGTGAAAAC CTCTTCTGCC CAGTTCGTAG GGAAACTGAG AAACAAGGAG 
GCCACAGAAG GGACCACGGT CACACTTCGG TGTGAGCTGA CCAAAGAGGC CCCCGTGGAG 
TGGAAGAAGG GAACAGAGAC CCTGAGAAAT GGGGACAAAT ACAGTCTGAA GCAGGATGGA 
GCTGTGTGTG AGCTGCAGAT CTGTAGTCTG CTGGTGGCAG ATGCAGGGGA GTACTCGTGT 
GTGTGTGGGC AGGAGAAGAC TTCAGCCACG CTGACTGTCA AGGCTCTGCT TGTCCACTTT 
GTCAGAAGGC TCAGGAGCAA GGAGGCCACA GAAGGAGACA CGACCACACT GCAGTGTGAA 
CTGAGCAAGG CTGCCCCCGT GGAGTGGAGG AAGGGAACAG AGACCCTGAG AGATGGGGAC 
AGATACAGCC TGAAGCAGGA TGGGGCTGTG TGTGAGCTGC AAATCCGCAG CCTGACCATA 
GCAGATGCTG GCGAGTACTT GTGCACGTGT GGACAGGAAA AGACCTCAGC CACGCTGACC 
GTCAGGGCCC TTCCAGCTAA GTTCAAAGAC AGTCTGAAGA ATGAAGAGGC TACAGAAGGC 
ACCACAGCTA CACTGAGCTG TGAACTGAGC AAGGCAGCTC CGGTGACATG GAAGAAAGGA 
CCGAAGACCT TGCAAAGTGG AGACAAATAT GTCCTGAGGC AGGATGGAGC TGTGTGTGGA 
CTACAGATCC ATGGCCTGAC CATGGCTGAT GCTGGGGAGT ACTCGTGTGT GTGTGGGCAG 
GAGAAGACGT CAGCCACGCT GACTGTCAGG GGCTTGCCTG CCAAATTTAT AGAAGATCTG 
AGAAGCCAAG AAGCCACAGA AGGGGCCACA GCAATCTTAA GATGTGAGCT GAGCAAGGCT 
GCTCCTGTGG AGTGGAGGAA AGGGTCTGAG ACCCTGAAAG ATGGGGACAG ATACACCCTG 
AGGCAGGATG GGGCCGTATG TGAGCTGCAG ATCCGTGGCC TGGCTGTGGT GGATACTGGG 
ACATACTCGT CCCTGCCCAC CAAGTTCACA GAGGGTCTGA GGAATGAAGA GGCCACGGAA 
GGCACCATGG CCACTCTGAG GTGCCAGATG AGCAAGGCTG CCCCTGTGGA GTGGAGGAAG 
GGGTCAGAGA CCCTGAGAGA TGGGGACAGA TACAGCCTGA GGCAGGATGG GGCCATGTGT 
GAGCTGCAGA TCCGTGGCCT GACCATAGAA GATTCTGGGG AGTACACATG TGTGTGTGGG 
CAGGAGAAGA CGTCAGCCAC ACTGAGTGTC AAGGCTCTGC CCCCCAGATT CATAGAAGAC 
TTGAGAAGCC AAGAGGCCAC AGAAGGCACC ATGGCCACTC TGAGGTGCCA GATGAGCAAG 
GCAGCCCCTG TGGAGTGGAG GAAGGGGTCT GAAACCCTGG GAGATGGGGG CAGATACAGC 
CTGAGGCAGA ATGGTGCTGT GTGTGAGCTG CAGATCCATG ACCTGGCTGT GGAAGACACT 
GGGGAGTACT CATGTGTGTG TGGGCAGGAG AAGACCTCAG CCACACTGAA TGTCAAGGCC 
CTGCCCCCCA GATTCATAGA AGACTTGAGA AGCCAAGAGG CCACAGAAGG CACCATGGCC 
ACTCTGAGGT GCCAGATGAG CAAGGCAGCC CCTGTGGAGT GGAGGAAGGG GTCTGAGACC 
CTGAGAGATG GGGGCAGATA CAGCCTGAGG CAGGATGGGG CTGTGTGTGA GCTGCAGATC 
CATGACCTGG ATGTGGAAGA TGCTGGCCAG TACTCGTGCG TGTGTGGGCA GGAGAAGACC 
TCAGCCGTGC TGACTGTAGA TGCACTGCCC CCCAAGTTTA CAGAGGGTCT GAAGAAGGAA 
GAGGCCACAG AAGGGACCAT GGTAACACTG AGGTGCCAGA TGAGCAAAGA AGCCACGGTG 
GAGTGGAGGA AGGGAGCAAA GACCCTCAGC GATGGGGGCA GATACAGCCT GAGGCAGGAT 
GGGGCCATGT GTGAGCTGCA GATCTGTGGC CTGGCTGTGG AAGACGCTGG GGAATACTCA 
TGTGTGTGTG GGCAGGAGAA GACCTCAGCC ACACTGAGTG TCAAGGCCCT GCCCCCCAGA 
TTCATAGAAG ACTTGAGAAG CCAAGAGGCC ACAGAAGGCA CCATGGCCAC TCTGAGGTGC 
CAGATGAGCA AGGCTGCCCC TGTGGAGTGG AGGAAGGGAT CCAAGACCCT GAGAGATGGG 
GACAGATACA GCCTGAGGCA GGATGGGGCC ATGTGTGAGC TGCAGATCTG TGACCTGGCT 
GTGGAAGACA CTGGGGACTA CTCATGTGTG TGTGGGCAGG AGAAGACCTC AGCCACACTG 
AGTGTCAAGG CTCCACAGGT GGTATTCCAG CAGCCACTGC AGAATCTGCA AGCAGAAGAA 
GGCTCCATGG CCAGCCTGCG GTGTGAGTTG TCAGTCCCCA ACGCTGCCAT GGTCTGGAGC 
AAGGGTGGTC TGGAGCTGCA GGGTGACACG CGCCGAGAGG CACGGCAGCA GGGGTGTGTG 
GCAGAGCTGT TGCTTAGGGA CCTGCGTCGC GAGGATGCGG GCGAGTACAG TTGCACCTGT 
GGCTCTCAGA CCACAAGCGC CACGCTCATG GTCACAGCTG CTCCTGTGCG GTTCCTCCGG 
GAACTGCAGG CCCAGGACGT AGATGAGGGG GCCACCGCAC GCCTGCGCTG TGAGCTGAGC 
CGGGAGGCTG TGAGCGTGGA GTGGCGCAAG GGCTCCTTGC AACTTTTTCC TTGTGCTAAG 
TATCAGATGG TGCAGGAGGG CACAACTGCG GAGCTGCTGG TCCATGGGGT GGAGCAGGAG 
GATGCAGGCG AATACACCTG CGATGCAGGC CACACGCAGA GCATTGCCAG GCTCTCTGTC 
CGAGCCCCCA AGCCCAAGTT CAAGACCGAC CTGCAAAGCA CAGAGCAGGA AGCAGGTGGC 
ACGGCACGGC TGTGTTGTCA ACTGAGCGAA GCTGAGCCAG GGACTCCAGT GCAGTGGCTC 
AAGGAGGGGG TGGAGCTGCA CGTCGGCTCC AAGTATGAGA TGCGGCGCCA AGGGGCTGTG 
TGCGAGCTGC TGATCCATGG GCTGGAGGCC AAGGACACTG GAGAATATGC CTGCCTGGTG 
GGTGGCCAGA AGACCTTGGC CTCCCTCAGA GTCAAAGAGC CTGAGGTGAC CATCGTGCGG 
GGACTCGTGG ACATGGAGGT GCAGGCCGAT GAGGATGTGG AGTTCACTTG CAAGGTGTCA 
CAGGCAGGAG CCACAGACGT GCAGTGGCAC CTCCAAGGTC TGCCACTGCA GAGCAATGAA 
GTGACAGAGG TGGCTGTCCT TGCGGACGGC TGTACCCATG TGCTCCAGTT AAAGGGTGTG 
ACACTGGAGG ATGCTGGTAC TGTCTCCTTC CACGTGGGCG GCCTTTCATC TTCTGCTCAG 
CTCACAGTCC GAGTCCCTGA GGTGACCGTT CTGGAGCCCC TGAAGGATGT GCAGCTCAGC 
GAGGGCCAGG ATGCCCACTT CCGGTGCCGA CTGTCCAGGG CCTCGGGCCA GGAGGCTCGC 
TGGGCTTTGG GAGGGGTTCC CTTGCAGTGC AACGAGATGA ACGACATCAC TGTGGAGCAG 
GGCACACTCT ACCTGCTCAC TCTGCACAAG GTGACCCTGG AGGATGCTGG GACCATCACT 
CTCCAAGTGG GCTCATGCTC CTCAGAGGCC CAGCTGAAGG TCACAGCCAA GAACACGGTG 
TTGCGTGGCC TGGAGAACGT GGATGCACTG GAGGGCGGTG AGGCTCTGTT CGAGTGCCAG 
CTGTCCCAGC CTGAAGTGGC CGCCCACACC TGGCTGCTGG ACGACGAGCC TGTGCACACG 
TCGGAGAAGG TGGAGGTGGT CTACTTTGAG AACGGACTGC GGCACCTGCT TCTACTCAAA 
AACCTGAAGC CACAGGACAG CTGCCGAGTG ACCTTCCTGG CAGGGGATGT GGTCACGTCC 
GCATTCCTCA CTGTGAGAGC TCTTCCTGAC CCCCCTGAAG ATGCTGAAGT GGTGGGGCGT 
AGTGACCATT CTGTGACCCT ATCCTGGGTG GCTCCCATGA GTGATGGAGG TGGGGGTCTA 
TGTGGTTATC GTGTGGAGAT GAAGGAGGCA TCCACAGGCC AGTGGCAGTT GTGCCATGAC 
TTGGTACCTG GTCCAGAGTG CGTGGTGGAC GACCTGGTCC CCGGGAAGAC CTACCGCTTC 
CGAGTGGCAG CTGTGGGTCC AGCAGGTGCT GGGGAGCCTG TACACTTGCC CCAGATGGTC 
AAGATAGCCC CAGCCCCGGC CCCGGCCCCG GCCCCTGCCC CAGCCCCTGC CCCAGAAACA 
CGGCAGGCAG TAGTTGGTGA AGACATCTGT CTGGAGTTGG AAGTGGCAGC TGATGGTGGC 
GAGGTCGTCT GGCACAAGGG AACAGAGCGC ATCCAGCCCG GAGGGCACTT TGAGGTCCTC 
TCTCGGGGTC AGCGGCAGAT GCTGGTGATC AAGGGCTTTA GGACCGAAGA CCAAGGGGAG 
TACCGCTGTG GTCCCATTCA GGGTCTGCCC TCCTCAGGAG CTGCCACGTT CAATGTGGTC 
ATGACCTCAG GCTCTGGGGA TGAGGTCCCG GCACAGCCTA GCCTGCCTCC CGAGGCAGCC 
CAGGAGGGTG ACCTGCATCT GCTTTGGGAG GCCCTTGCCC GGAAGCGCCG CATGAGTCGG 
GAGCCCACGC TGGACTCCAT CAGTGAGCTG CCTGAGGAAG ACAGCCGTGT GCAGCATCTG 
CGGCAGGAGG CAGAAGAGAC AGCTCCCGAC CTCTCTGAAG GCTACTCTAC AGCGGATGAG 
CTAGCACGCA CAGGAGAGGC CGACCTCTCA CACACCAGCT CTGACGATGA GTCTCGGGCT 
GGCACCCCTT CCCTAGTTAC CTACCTCAAG AAGGCCGGGG GTCCTGGGAT CTCACCCTTG 
GCCAGCAAGC ATGAGGCCCA GGTGACCACG TCTGTGAAGC CACAAAAGCA GCAGGAGCCA 
GTCGTGCCCA CGTGCCCACC GCCGGGAGAC TTGAGTGCAG CAGATTTGAT GGATCCATCC 
CTGGACAAGG CTGCTGTGAA GATTCAGGCT GCCTTTAAGG GTTACAAAGT GCGGAAGGAG 
ATGAAACAGC AGGAAGGGCC TGTGTTCTCA CGAACATTTG GGGACACAGA GGCACAGGTT 
GGGGATGTGC TGCGGCTAGA GTGTGTGCTG GCCACCAAGA CTGATATGCG GGCCTGCTGG 
TTGAAGGATG GCATCGAGTT AACAGATGGG CGCCATTACC ACATAGACCA GCTCAAGGAT 
GGTACCTGCT CTCTGCTGGT CACTGGCCTG GCCCCCACTG ACTCTGGCCG TTACACCTGT 
CAGGTGAGCA CCAAGTCTGG CCGTGTGAGC CACAGTGCCT GCGTGGTGGT CAGTGGGACA 
GAGAGCGAGG CCGAGAGCTC CTCTGGGGGC GAGCTGGATG ATGCTTTCCG CCGGGCAGCG 
AGACGCCTGC ACCGCCTCTT CCGCACCAAG AGCCCAGCTG AGCTTTCAGA GGAGGAACTC 
TTCCTCAGCG CTGATGAAGG CCCCGGGGAG CCAGAGGAGC CCGCAGACTG GCAAACATAC 
CGAGAGGATG AGAACTTTGT GTGCATCCGT TTTGAGTCCC TTGCAGAGGC CCGCCAGGCA 
GTCACCTGCT TCCGAAACAT GTTTGCCACT ATGGGCATCG GGGTGGAGAT CAGCCTAGGG 
GAGCAGGGAC CCCGGGGAGT GGAGATGCGC ATCGGCAAGG TGGCCCCTAC TGTCACCCCT 
GCAGTGCCGC TTGCAAAGAC ACCTGGCCTG CAGACTTCAG ATGCTGCCCC AGTGTTCCTG 
ACCGAGCTGC AGAACCAAGA TGTGCAGGAT GGATACCCCA TGAGCTTCGA CTGCGTGGTA 
ACGGGCCAGC CTGTGCCCAG TGTGCGCTGG TTCAAGGATG GGAAGCTGCT AGAAGAGGAT 
GACCACTATA TGATCAATGA GGACCAACAG GGGGGTCACC AGCTCATCAT CACAGCTGTG 
GTGCCGGCAG ACATGGGTGT CTACCGCTGC CTGGCGGAGA ACAGCATGGG CGTCTCCTCC 
ACCAAGGCTG AGCTTCGTGT GGAATTGACC AGCACAGACT ATGATACTGC TGCGGATGCT 
ACTGAGACCT CATCCTACTT CAGCGCCCAG GGATACCTGT CCAGTCGGGA GCAAGAGGGA 
ACGGAGTCAG ATGAGGGGCA GCTTCCCCAG GTGCTGGAGG AACTGAAAGA CCTCCAAGTG 
GCCCCCGGGA CACGCCTGGC CAAGTTCCAG CTCAAGGTGA AAGGCTATCC AGCTCCCAAA 
CTGTATTGGT TCAAAGATGG CCAGCCCCTG ACCACGTCTG ACCACATCCG CATGACTGAC 
AAGAAGACCC TGCACACCCT GGAGATTGTC TCGGTCACTC GGGAGGACAG CGGCCAGTAT 
GCAGCCTACA TCAGCAATGC TGTGGGTGCT GCCTATTCGT CAGCCCGGCT TCTGGTCCGA 
GGTCCCAGTG AACCAGAAGA GAAGCCAGCA TCAGATGTTC ATGAGAGGCT GGTGCCACCC 
CGAATCCTGG AGAAGTTCAC CCCCAAGAAA GTGAAGAGGG GCTCCAGCAT CACCTTTTCA 
GTGAAGGTGG AAGGACACCC GGCCCCCAGT GTGCATTGGC TCAAGGAGGA GGCAGAGAAG 
GGAGTCCTGT GGATTGGCCC TGACACCCCG GGCTACACCA TGGCCAGCTC TTCCAAGCAG 
CATAGCCTGG TCCTGCTGGA CGTAGGCCGA CAGCACCAGG GCACCTACAC ATGTATTGCT 
ACCAACCCTG CTGGCCAGGC GCTCTGCTCT GCCAGCCTGC ACATCTCTGG CTTGGCCAAA 
GAAGAAGAGC AGGAGAGAGT GAAGGAGGCC CTCATTTCCT CTTTCCTGCA AGGGACAAGC 
CAAGCTGTCT CAGCCCAGAT GTCAGAATCC GCAGGTTTTG CTGATCTTGT CGGGCAAAGC 
AAAGGCGAGT CTCTGGTGGC TGAGGAGGCC CACAGTCACC TGTCCCTTGC TGAGGTGGGC 
ACTGAAGAGT TCCTGCAGAA ACTCACCTCG CAGATCACGG AGATGGTATC GGCCAAGATC 
TCTCAGGCCA AACTCCAGGT GCCTGGAGGT GACAGCGATG AAGAGACCAA GACACCATCT 
GCTTCTCCTC GGCATGGCCG GTCACGTCCT TCCTCCAGTG TTCAAGAGTC CTCCTCAGAG 
TCAGAGGATG GGGACTCCCG TGGTGAGATC TTTGACATCT ATGTGGTCAC AGCTGACTAT 
CTGCCACTGG GAGCTGAGCA GGATGCCATC ATTCTGAGAG AAGGCCAGTA TGTGGAGGTC 
CTTGACTCTG CCCATCCCCT GCGCTGGCTT GTCCGGACCA AGCCCACCAA ATCCAGTCCT 
TCCAGGCAGG GCTGGGTGTC ACCTGCCTAC CTGGATAAGA GGCTCAAGCT GTCTCCTGAG 
TGGGGGCCCA CTGAGGCCCC CGAGTTCCCT GGCGAGGCTG TGTCTGAGGA TGAGTATAGA 
ACGAGGCTGA GCTCTGTCAT CCAGGAGTTG CTGAGTTCAG AGCAGGCTTT TGTGGGTGAG 
CTGCAGTTCT TGGAGAGCCA CCACATGAAG CACCTGGAGC GATCTCCCCG AGTACCCGCA 
GCTGTGGCCA GCCAGAAGAC AGTCATCTTT CGTAATGTGC AGGACATCAG CCATTTCCAC 
AGCAGCTTCT TGAAGGAGCT GCAGGGCTGT GGCACCGACG ATGATGTGGC CATGTGCTTC 
ATCAAGAACC AGGAGGCCTT TGAGAAGTAC CTCGAGTTCC TGGTGGGCCG CGTGCAAGCT 
GAATCAGTGG TTGTCAGCAC CCCAGTCCAG GAGTTCTACA AGAAATATGC AGAAGAGACA 
CTGTCAGCCA AGGACCCCAC ACAGCCACCC CCACCTCCTC TTCAGCACTA CCTGGAGCAG 
CCAGTGGAAC GGGTGCAGAA ATACCAGGCC TTGCTGAAGG AGCTAATCCG CAACAAGGCC 
CGCAACCGGC AGAACTGCGC GCTGCTGGAG CAGGCCTATG CTGTGGTGTC TGCCCTGCCT 
CAGCGCGCCG AGAACAAGCT GCACGTTTCT CTCATGGAGA ACTACCCAGG AACCCTGGAG 
GCCCTGGGAG AACCTATCCG CCAGGGCCAC TTCATAGTGT GGGAGGGGGC CCCAGGGGCC 
CGGATGCCTT GGAAGGGCCA CAACCGGCAC GTCTTCCTCT TCCGAAACTA CCTGGTGATC 
TGCAAGCCCC GAAGAGACTC TCGAACCGAC ACCTTCAGCT ATGTGTTCCG GAACATGATG 
AAGCTGAGTA GCATCGACCT GAATGACCAA GTAGAGGGGG ATGACCGCGC CTTTGAGGTG 
TGGCACGAAC GGGAAGACTC TGTGCGCAAG TACCTGCTGC AGGCACGGAC CGTCATCATC 
AAAAACTCCT GGGTGAAGGA GATCTGTGGC ATCCAGCAGC GCCTGGCCCA GCCTGTGTGG 
CGTCCCCCTG AGTTTGAAGA GGAACTAGCG GACTGCACAG CCGAGCTGGG TGAAACGGTC 
AAGCTAGCAT GCCGAGTGAC GGGCACACCT AAGCCTATTG TCAGCTGGTA CAAAGATGGG 
AAGCCAGTGG AGGTGGACCC ACACCACATC CTCATTGAAG ACCCTGACGG CTCCTGCACC 
CTCATCTTGG ACAACCTTAC TGGCATAGAC TCTGGCCAGT ACATGTGTTT TGCGGCCAGT 
GCTGCTGGCA ACGCCAGCAC CTTGGGGAAG ATTCTAGTAC AAGTGCCCCC ACGGTTTGTG 
AACAAGGTCC GGGCCACACC CTTTGTGGAG GGAGAGGATG CACAGATCAC CTGCACAGTG 
GAAGGAGCCC CGTACCCTCA GATCAGGTGG TACAAGGATG GTACCCTGCT AGCCCCGGGC 
AACAGGTACC GGATGTTGAA TGAACCCCGC AGTGGTGTGC TGGTGCTGGT GATCCAGGCG 
GCCAGCAAGG AGGACCTGGG ACACTATGAA TGTGAGTTGG TGAACCGGTT GGGCTCAACA 
CGTGGTGGTG GAGAACTATA CATGCAGAGC CCTGCACTGC GTGCCCGGGA CCAGCACCAC 
CGGGAACAGA TTGTGGCTGC CGTAGAAGGG GCCCCGTCCA TGCAGGTCAC TATTGAGGAT 
GTACAAGTAC AAGTAGGGGA CATGGCACAG TTTGATGCTG TCATTGAAGG CCACCCACCA 
CCCATAGTAA CCTGGTACAA GGGCAGCACC CAGCTGACGA GCAGTGCCCG GCTGAGCCAA 
CGGCAAGATG GAACGACATA CTCCTTGGTG TTGACTGACG TGGCTCCACA CGATGCCGGT 
GTCTACACAT GTGTTGCCAA TAATGCAGGT GGACAGGTGC TCTGCAAGGC AGAGCTGCTG 
GTCCATGGGG GGGACAAGCT AGATGCCGAA AATCAAGTCT ATCGGAGAAA ACTGCATTCC 
TTCTATGACG TTCAAGAAGA GATTGGGAGG GGTGTGTTTG GGTTTGTGAA AAGGGTTCAG 
CACAAAGGAA ACAAGATGTT CTGTGCCGCC AAGTTCATCC CCCTACGGAG TAAAACTCGG 
GCCCAGGCAT ACCAGGAACG AGACATCTTG GCTACACTCG GCCACCCACT GGTCACTGGG 
CTCCTGGATC AATTTGAGAC CCGGAAGACT CTCATCCTTA TCTTGGAACT GTGCTCGTCT 
GAGGAGCTGC TGGATCGGCT CTTCAAGAAG GGTGTAGTGA CTGAAGCCGA GGTCAAAGTC 
TATATCCAGC AGCTGGTGGA AGGCCTACAC TATTTGCACA GCCATGGTAT CCTCCACCTG 
GACATAAAGC CCCCCAACAT CCTGATGGTG CACCCAGCTC GGGAAGACAT CAAGATCTGT 
GACTTTGGCT TTGCCCAAAA GATCACCCCT TCAGAGCCAC AGTACAGCAA GTATGGCTCA 
CCCGAATTCG TGTCCCCAGA GATCATTGAG CAGAATCCTG TGAGCGAGGG CTCAGACATC 
TGGGCCATGG GCGTCATCTC CTACCTCAGC CTCACCTGCT CATCCCCATT TGCTGGAGAG 
AGTGACCGCG CCACCTTGCT CAATGTTTTG GAGGGGCGGG TCTCCTGGAG CAGTCCCACG 
GCTGCTCATC TGAGTGAGGA CGCCAAGGAC TTCATCAAGG CCACGCTGCA AAGGACCCCC 
AGGGCCAGGC CTAGTACTTC CCAGTGCCTT GCCCACCCCT GGTTCCTGAA ATCCATGCCT 
GCTGAGGAGG CCCACTTCAT CAACACCAAA CAGCTCAAGT TCCTTCTTGC TCGAAGTCGC 
TGGCAGCGTT CCTTGATGAG CTACAAGTCT ATCCTGGTGA TGCGCTCCAT CCCTGAGCTG 
CTTCAGGGTC CCCCAGACAG TCCATCTCTA GGAGTGGCCC GGCACCTACG AGGGGAAGCC 
AGTGGCGCCT CTAGCTCATC ATCTTCCTCA GACAACGAGC TTGCCCCATT TGCCAGGGCT 
AAGTCGCTGC CACCTTCTCC TGTGACTCAC TCGCCACTGC TGCACCCTCG GGGCTTTCTG 
CGGCCTTCGG CCAGCCTCCC AGAGGAGACA GAGGCCAGCA TGCCCACTGC TGATGCGGCC 
GTGCCAGCGT CCCCACAGAG TGCTGGGCCT CCGGCAAGCC CAGGTTGTGT GCCCCGGCAC 
AGCGTCATCA GCAGCCTGTT CTACCAGCAA GCTGGCGAGG GTGCAGAGCG TGGGAACAAA 
ACATCGGGTG CCAAGAGGCA CCCTGCGCGG AGGCGGCACC TGCTAAAGGG TGGGTACATT 
GCAAGGGCCT TACCCGGTCT GCGTGAGCCC CTCATGGAGT ACAGCTTGTT GGAGGAAGAG 
GCGGCTAGGG AAGAGCAGGC CTCTCTGATG ACCAAGACAC CCTCCTTTGA GACTGCCCTG 
CGACTACCTA GTTCCAGTGT CAGAGAGGTC CCAGGCCGAA GCCACTCCCT GGACAACCCA 
CCAGTCACGA CTGGCCCCTC TCCTGAGGCA TGCAAGGAAC AACTCCTGTT CCCACCCTCC 
ACGGGGTTGA CTCATGAAAC CACTGCCAAG GACAGGGGGC ACAAAGAGGG GTTCTTGCAG 
GAGTCTGTCC CCTTTCCACC TATGAGTGGT GACTCGAGGC CTGGGAAGCA AGAGGGATCA 
TCCCAGGACA GTTGTAGAGG GAAACCAGCC TCTTCCTGTC ACTCTGAGCT GGGTTCTGGT 
TCCCAGGAGG GCTGTGGCCC TCCATCATCT CAATCGCTTG GCTCCTTACC TCCACAGTCA 
TTGAAGAAGG AGCTCTCAAC GTCCTGTGGC CCACTCTTTT CAGAACAGCC TCAGGCAGCC 
CCATTCCCAA CTCAAGTAAG CCCCCTTCTG GGTTCTGAGA AGGAACCTCA GGATGGCTCT 
CTATCTGAAG GGCCAGTTCC AGTTCCCTCC AGTTCTCCAG GGTCAGCTTC CCAAGTAGAT 
GCATCCTTGG ATACTGAAGG CTTGTCTGAA GCTGGGGACA CATGTGACTT CACGCCTCCT 
CCACAGCGGC CTCAGGAGCA GGCCACCACC CGGAAGTTCT CTCTGGAGTC CCGTGGGGGC 
TATGCAGGGG TGGCAGGCTA TGGTACTTTT GCCTTTGGCG GGGATGCAGG GGGGATGCTA 
GGGCAGGGTC CTCTCTGGGC CAGGATGGCC TGGGCTGTGT CCCAGTCCTC AGAAGAGCAG 
GATGAAGCTG CGACTGAGAG CCCTCAACCT CTGGAGAGCT TGGGGCCCAT TGCTGAGGCC 
AGTGGGGTTC CCCTAAGGAC CTCTCCAAGC CTCACCCCTT GGGAGGAAGT TGAGCAGGTT 
TCCCTGGTGC AGATCCGGGA TCTGTCTGGT GATGCGGAAG CAGCTGACAC TATCTCCTTG 
GACATTTCTG AGGTCGATCC TGCCTACCTC AACCTCTCGG ATCTATATGA CATCAAATAT 
CTCCCATTTG AGTTCATGAT CTTCAGAAGG GTCCCCAAAC CTATAGAGCA GCCAGAGTCA 
CCTGGCTCAG AAACCGAAGC TGGGCAAGGG CTGGCAGATT TCCTGGAGGA GGCCGCGTGG 
CCCTGGCCAG GCGAGCTGGG ACTGCGTGCT GGTCTGGAGA TTACAGAGGA GCCGGAGGAG 
CCAGGGGACC TGGAAGCACT GCTGGGCGAG GCTGCTGTGG GCAGGAAGCG CAAGTGGTCC 
CCCTCCCGGG GCCTCTTCCA ATTCCCTGGG AGGTGCCTGT CAGGGGAGGA GCCTGTGGAG 
CTTGGGCTGC GCCAGAGGGT GAAGGCTTCC ATGGCTCACA TCTCCAGGAT CCTCAAGGGC 
AGGCCGGAAG GTCCTGAGAG GGAAGGGCCT CCCAGAAAGA AGGCAGGCCT AGCTTCTTTC 
CGGCTGTCAG GCCTGAAGGG CAGGGACCAA GAACTCTCAG ACGAGGCTGT GGTCCTGGGC 
CAATCAGTGA CACTGGCCTG CCAGGTGTTG GCCCAGCCAA CTGCCCAGGC TACCTGGAGC 
AAAGATGGGG TCCTCCTGGA GAGCAGCGGC CACCTCCTCA TCTCCTCCAC CCTGAAGAAC 
TTCCAGCTGC TGACCATCCT GGTGGTGAAA GAGGAGGATC TGGGCACATA TACCTGCTGT 
GTGAGCAACC CGCTGGGGAC AGCAGTCACC ACAGGTGTCC TCCGGAAAGC AGAGCGCCCT 
TCATCTTCTC CACGCCCTGA GGTGGGGGAA CTATACAAGG ATGCGGTGCT GCTGGTCTGG 
AAGCCTGTGG AATCCTGTGG CCCGGTGACC TACATTGTGC AGTGCTGTAT AGAAGGAGGC 
AGCTGGACAA CCCTGGCTTC AGACATCTCT GACTGCTGCT ACCTCACTGG CAAGCTATCG 
AGGGGTGGCA TGTATATCTT CCGGACAGCA TGTGTCAGCA AAGCAGGAAT GGGCCCCTAC 
AGCAGCCCCT CAGAACAGGT CCTCCTCGGA GGACCCAACC ACCTGGCCTC TGAGGAGGAA 
AGCAGCCGGG GGAGGCCAGC CCAGCTTCTC CCCAGCACAA AGACCTTTGC CTTCCAGATG 
CAGATCCGGA GGGGCCGCTT CAGTGTGGTG CGGCAGTGCA GGGAGAAGGC AAGTGGGCGG 
GCCCTAGCTG CTAAGATCGT TCCCTACCAA CCTGAGGACA AGACAGCTGT ACTAAGAGAA 
TACGAGGCAC TTAAGAGACT GCACCACCCA CATCTGGCCC AACTCCATGC CGCCTACCTC 
AGTCCCCGGC ACCTGGTGCT CATCCTGGAG CTGTGCTCTG GCCCTGAGCT GCTACCCTCT 
TTGGCAGAGA GGGAATCCTA CTCAGAGTCT GATGTGAAGG ACTACCTGTG GCAGATGCTG 
AGTGCCACCC AGTACCTGCA TGCCCAACAC ATCCTGCACC TGGACCTGAG GTCCGAGAAC 
ATGATGGTCA CTGAGTACAA CCTGCTTAAG GTTATAGACC TGGGAAATGC CCAGAGTCTC 
GACCAAGAGA AGGTCCCAGC CCCTGAGAAC TTCAAAGACT ACCTGGAGAC CATGGCTCCA 
GAACTCCTGG AAGGTCAAGG GGCTGTTCCA CAGACAGACA TTTGGGCTAT TGGTGTAACA 
GCCTTCATTA TGCTGAGTGG CGAGTACCCA GAGAGCAGCG AGGGGACTCG CGACCTGCAG 
AAAGGCTTGC GCAAGGGACT CATTCGGTTG AGTCGCTGCT ATGCAGGATT ATCAGGAGGA 
GCCGTAGCCT TCCTGCAGAG TTCATTATGT GCTCAACCCT GGGGCCGCCC GTGCGCTTCC 
ACCTGCTTGC AATGCGGATG GCTGACAGAG GAGGGCCCCA CCGGCTCCCG GCCCACGCCC 
GTAACCTTCC CCACCGTGCG GTTGCGCGCC TTTGTGCGCG AGCGCGAGAA GCGGCGTGCG 
CTCCTCTACA AGAAGCATAA CCTGGCCCAG GTGCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.
Journal of molecular and cellular cardiology11127-39(2017 Oct)
Ackermann MA,King B,Lieberman NAP,Bobbili PJ,Rudloff M,Berndsen CE,Wright NT,Hecker PA,Kontrogianni-Konstantopoulos A

Deregulated Ca
Science advances3(6)e1603081(2017 Jun)
Hu LR,Ackermann MA,Hecker PA,Prosser BL,King B,O'Connell KA,Grogan A,Meyer LC,Berndsen CE,Wright NT,Jonathan Lederer W,Kontrogianni-Konstantopoulos A

Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice.
American journal of physiology. Cell physiology312(1)C16-C28(2017 Jan)
Randazzo D,Blaauw B,Paolini C,Pierantozzi E,Spinozzi S,Lange S,Chen J,Protasi F,Reggiani C,Sorrentino V

The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.
Molecular biology of the cell20(17)3905-17(2009 Sep)
Ford-Speelman DL,Roche JA,Bowman AL,Bloch RJ

Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.
Journal of cell science122(Pt 15)2640-50(2009 Aug)
Lange S,Ouyang K,Meyer G,Cui L,Cheng H,Lieber RL,Chen J

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Obscn cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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