Slc9a9 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc9a9
Entrez Gene ID	331004
Full Name	solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms	5730527A11Rik,9930105B05,AI854429,Nhe9
General protein information	Preferred Names solute carrier family 9 (sodium/hydrogen exchanger), member 9 Names sodium/hydrogen exchanger 9 Na(+)/H(+) exchanger 9 solute carrier family 9 member 9
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 E3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_177909.5	NP_808577.3	sodium/hydrogen exchanger 9

Pathways from BioSystems

Homologies

	SLC9A9	XP_001111715.1
Kluyveromyces lactis	KLLA0B01738g	XP_451608.1
Schizosaccharomyces pombe (fission yeast)	SPAC15A10.06	NP_594293.2
Mus musculus (house mouse)	Slc9a9	NP_808577.3
Saccharomyces cerevisiae (baker's yeast)	NHX1	NP_010744.3
Pan troglodytes (chimpanzee)	SLC9A9	XP_001162912.1
Homo sapiens (human)	SLC9A9	NP_775924.1
Canis lupus familiaris (dog)	SLC9A9	XP_854179.2
Magnaporthe oryzae (rice blast fungus)	MGG_06437	XP_003717132.1
Neurospora crassa	NCU00453	XP_956772.2
Bos taurus (cattle)	SLC9A9	NP_001069536.1
Rattus norvegicus (Norway rat)	Slc9a9	NP_001258367.1
Gallus gallus (chicken)	SLC9A9	NP_001026476.1
Eremothecium gossypii	AGOS_AER308C	NP_985164.1
Xenopus tropicalis (tropical clawed frog)	slc9a9	XP_002938455.2

Gene Ontology
Bibliography

Related articles in PubMed

Autism spectrum disorder traits in Slc9a9 knock-out mice.
Yang L, Faraone SV, Zhang-James Y
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics171B(3)363-76(2016 Apr)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development.
Ouyang Q, Lizarraga SB, Schmidt M, Yang U, Gong J, Ellisor D, Kauer JA, Morrow EM
Neuron80(1)97-112(2013 Oct)

Functional evaluation of autism-associated mutations in NHE9.
Kondapalli KC, Hack A, Schushan M, Landau M, Ben-Tal N, Rao R
Nature communications42510(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This is the first animal behavior study that links Slc9a9 to Autism spectrum disorders.
Title: Autism spectrum disorder traits in Slc9a9 knock-out mice.

Loss-of-function mutations in NHE9 may contribute to autistic phenotype by modulating synaptic membrane protein expression and neurotransmitter clearance.
Title: Functional evaluation of autism-associated mutations in NHE9.

NHE9/Slc9a9 is expressed in the inner ear
Title: Vestibular hair bundles control pH with (Na+, K+)/H+ exchangers NHE6 and NHE9.

The following Slc9a9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc9a9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu19605	NM_177909.5 Latest version!	Mus musculus solute carrier family 9 (sodium/hydrogen exchanger), member 9 (Slc9a9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc9a9 ( NM_177909.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_808577.3 Mus musculus solute carrier family 9 (sodium/hydrogen exchanger), member 9 (Slc9a9), mRNA.

Price & Availability↑

CloneID	OMu19605
Clone ID Related Accession (Same CDS sequence)	NM_177909.5
Accession Version	NM_177909.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	sodium/hydrogen exchanger 9
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB838484.1, AK037058.1 and AC157517.2. On Apr 21, 2010 this sequence version replaced NM_177909.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC099942.1, AK156494.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGGGC AGCTTCGGTT TACGTCAGGG AAGGATGAAG ATCATTTTCA ACACCAGGGA 
GCAGTGGAGC TACTCGCGTT TAATTTTTTG CTCATCCTTA CCATTTTAAC AATCTGGTTA 
TTTAAAAATC ACCGATTCCG CTTCTTGCAT GAGACTGGAG GGGCGATGGT GTATGGCCTC 
ATAATGGGAC TAATTTTGCG ATATGCCACA GCGCCGACTG ATATTGATAG TGGAACTGTC 
TACAACTGTG GGAACTTGTT CTTCAGCCCA TCAACTCTAC TAGTCAACAT CACCGACCAA 
GTTTATGAGT ATAAGTACCA GAGAGAGATC AACCAGCACA ATATCAGCCC CCACCAAGGC 
AACGCCATAC TGGAGAAGAT GACGTTTGAC CCAGAAATCT TCTTCAACGT TTTGCTGCCT 
CCCATCATAT TTCATGCAGG ATACAGTCTG AAGAAGAGAC ACTTTTTTCA AAACTTGGGA 
TCCATTTTAA CATATGCCTT CTTGGGAACA GCCATCTCCT GTGTGGTCAT AGGGTTAATT 
ATGTACGGCT TTGTGAAAGC CATGGTGCAT GCTGGCCAGC TGAAGAGCGG AGACTTCCAC 
TTCACTGACT GTTTATTTTT TGGTTCACTG ATGTCTGCTA CAGATCCAGT GACAGTGCTG 
GCCATTTTCC ATGAACTCCA CGTGGACCCA GACCTGTACA CACTGCTGTT TGGAGAGAGT 
GTACTGAATG ATGCGGTGGC CATAGTCCTC ACATACTCTA TATCCATCTA TAGTCCCAAG 
GAGAATCCCA ACGCGTTTGA CACGGCAGCG TTCTTCCAAT CCGTGGGCAA TTTCCTAGGG 
ATCTTTGCCG GCTCCTTTGC AATGGGCTCC GCATATGCAG TTGTTACCGC ACTGTTGACC 
AAATTTACCA AGCTCCGTGA GTTCCCGATG CTGGAGACAG GCCTGTTTTT CCTCCTTTCT 
TGGAGTGCCT TCCTGTCTGC AGAGGCCGCC GGCTTAACAG GCATAGTTGC TGTTCTCTTC 
TGTGGAGTCA CACAGGCACA TTACACCTAC AACAATCTGT CATCGGATTC CAAACTGAGG 
ACCAAACAGC TGTTTGAATT TATGAACTTC CTGGCTGAAA ACGTCATCTT CTGCTACATG 
GGCCTGGCTC TGTTCACCTT CCAGAATCAC ATTTTCAATG CTCTTTTTAT ACTCGGAGCC 
TTTCTAGCAA TTTTTGTTGC CAGAGCCTGC AACATTTACC CCCTCTCCTT CCTCCTGAAT 
CTGGGCAGAA AGCAGAAGAT TCCCTGGAAC TTCCAGCACA TGATGATGTT TTCAGGTTTG 
CGAGGTGCCA TTGCCTTCGC CCTGGCCATC CGCAACACGG AATCTCAGCC CAAACAGATG 
ATGTTCACCA CCACACTGCT CCTTGTGTTC TTCACTGTCT GGGTGTTTGG AGGAGGAACG 
ACCCCCATGC TGACGTGGCT TCAGATCAGA GTTGGTGTGG ACCTGGATGA AAGTCTGAAG 
GAAGAGCCCT CCTCACAGCA GGAAGCAAAT AAGTTGGACA AAAACATGAC GAAGACAGAG 
AGTGCACAGC TCTTCAGAAT GTGGTATGGA TTTGACCACA AATACCTGAA ACCCATCCTA 
ACACACTCAG GCCCTCCACT GACCACCACC TTGCCAGCGT GGTGTGGCCC AGTCTCCAGG 
CTGCTCACCA GTCCGCAGGC CTATGGGGAA CAACTGAAAG AGGATGACGT GGAATGTATC 
GTCAACCAAG ATGAACTGGC CATGAATTAC CAGGAGCAGA GCCCTTCACC CAGCAGTCCC 
ACCACCAAGC TAGCTCTGGA CCAGAAGTCT TCAGGCCAGA CTCCAGGCAA GGAGAATATC 
TACGAGGGAG ATCTCGGCCT GGGAGGCTAT GATCTCAAAC TGGAGCAGAC TCGGGGTCAA 
CCCCAGATGG ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808577.3
CDS	171..2105
Translation	MAGQLRFTSGKDEDHFQHQGAVELLAFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLILRYATAPTDIDSGTVYNCGNLFFSPSTLLVNITDQVYEYKYQREINQHNISPHQGNAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCVVIGLIMYGFVKAMVHAGQLKSGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDTAAFFQSVGNFLGIFAGSFAMGSAYAVVTALLTKFTKLREFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKLRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDESLKEEPSSQQEANKLDKNMTKTESAQLFRMWYGFDHKYLKPILTHSGPPLTTTLPAWCGPVSRLLTSPQAYGEQLKEDDVECIVNQDELAMNYQEQSPSPSSPTTKLALDQKSSGQTPGKENIYEGDLGLGGYDLKLEQTRGQPQMD

Target ORF information:

RefSeq Version	NM_177909.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 9 (sodium/hydrogen exchanger), member 9 (Slc9a9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177909.5

ORF Insert Sequence:

ATGGCTGGGC AGCTTCGGTT TACGTCAGGG AAGGATGAAG ATCATTTTCA ACACCAGGGA 
GCAGTGGAGC TACTCGCGTT TAATTTTTTG CTCATCCTTA CCATTTTAAC AATCTGGTTA 
TTTAAAAATC ACCGATTCCG CTTCTTGCAT GAGACTGGAG GGGCGATGGT GTATGGCCTC 
ATAATGGGAC TAATTTTGCG ATATGCCACA GCGCCGACTG ATATTGATAG TGGAACTGTC 
TACAACTGTG GGAACTTGTT CTTCAGCCCA TCAACTCTAC TAGTCAACAT CACCGACCAA 
GTTTATGAGT ATAAGTACCA GAGAGAGATC AACCAGCACA ATATCAGCCC CCACCAAGGC 
AACGCCATAC TGGAGAAGAT GACGTTTGAC CCAGAAATCT TCTTCAACGT TTTGCTGCCT 
CCCATCATAT TTCATGCAGG ATACAGTCTG AAGAAGAGAC ACTTTTTTCA AAACTTGGGA 
TCCATTTTAA CATATGCCTT CTTGGGAACA GCCATCTCCT GTGTGGTCAT AGGGTTAATT 
ATGTACGGCT TTGTGAAAGC CATGGTGCAT GCTGGCCAGC TGAAGAGCGG AGACTTCCAC 
TTCACTGACT GTTTATTTTT TGGTTCACTG ATGTCTGCTA CAGATCCAGT GACAGTGCTG 
GCCATTTTCC ATGAACTCCA CGTGGACCCA GACCTGTACA CACTGCTGTT TGGAGAGAGT 
GTACTGAATG ATGCGGTGGC CATAGTCCTC ACATACTCTA TATCCATCTA TAGTCCCAAG 
GAGAATCCCA ACGCGTTTGA CACGGCAGCG TTCTTCCAAT CCGTGGGCAA TTTCCTAGGG 
ATCTTTGCCG GCTCCTTTGC AATGGGCTCC GCATATGCAG TTGTTACCGC ACTGTTGACC 
AAATTTACCA AGCTCCGTGA GTTCCCGATG CTGGAGACAG GCCTGTTTTT CCTCCTTTCT 
TGGAGTGCCT TCCTGTCTGC AGAGGCCGCC GGCTTAACAG GCATAGTTGC TGTTCTCTTC 
TGTGGAGTCA CACAGGCACA TTACACCTAC AACAATCTGT CATCGGATTC CAAACTGAGG 
ACCAAACAGC TGTTTGAATT TATGAACTTC CTGGCTGAAA ACGTCATCTT CTGCTACATG 
GGCCTGGCTC TGTTCACCTT CCAGAATCAC ATTTTCAATG CTCTTTTTAT ACTCGGAGCC 
TTTCTAGCAA TTTTTGTTGC CAGAGCCTGC AACATTTACC CCCTCTCCTT CCTCCTGAAT 
CTGGGCAGAA AGCAGAAGAT TCCCTGGAAC TTCCAGCACA TGATGATGTT TTCAGGTTTG 
CGAGGTGCCA TTGCCTTCGC CCTGGCCATC CGCAACACGG AATCTCAGCC CAAACAGATG 
ATGTTCACCA CCACACTGCT CCTTGTGTTC TTCACTGTCT GGGTGTTTGG AGGAGGAACG 
ACCCCCATGC TGACGTGGCT TCAGATCAGA GTTGGTGTGG ACCTGGATGA AAGTCTGAAG 
GAAGAGCCCT CCTCACAGCA GGAAGCAAAT AAGTTGGACA AAAACATGAC GAAGACAGAG 
AGTGCACAGC TCTTCAGAAT GTGGTATGGA TTTGACCACA AATACCTGAA ACCCATCCTA 
ACACACTCAG GCCCTCCACT GACCACCACC TTGCCAGCGT GGTGTGGCCC AGTCTCCAGG 
CTGCTCACCA GTCCGCAGGC CTATGGGGAA CAACTGAAAG AGGATGACGT GGAATGTATC 
GTCAACCAAG ATGAACTGGC CATGAATTAC CAGGAGCAGA GCCCTTCACC CAGCAGTCCC 
ACCACCAAGC TAGCTCTGGA CCAGAAGTCT TCAGGCCAGA CTCCAGGCAA GGAGAATATC 
TACGAGGGAG ATCTCGGCCT GGGAGGCTAT GATCTCAAAC TGGAGCAGAC TCGGGGTCAA 
CCCCAGATGG ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Autism spectrum disorder traits in Slc9a9 knock-out mice.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics171B(3)363-76(2016 Apr)
Yang L,Faraone SV,Zhang-James Y

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development.
Neuron80(1)97-112(2013 Oct)
Ouyang Q,Lizarraga SB,Schmidt M,Yang U,Gong J,Ellisor D,Kauer JA,Morrow EM

Functional evaluation of autism-associated mutations in NHE9.
Nature communications42510(2013)
Kondapalli KC,Hack A,Schushan M,Landau M,Ben-Tal N,Rao R

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Slc9a9 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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