Lrig3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrig3
Entrez Gene ID	320398
Full Name	leucine-rich repeats and immunoglobulin-like domains 3
Synonyms	9030421L11Rik,9130004I02Rik,9430095K15Rik,mKIAA3016
General protein information	Preferred Names leucine-rich repeats and immunoglobulin-like domains 3 Names leucine-rich repeats and immunoglobulin-like domains protein 3 LIG-3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_177152.5	NP_796126.4	leucine-rich repeats and immunoglobulin-like domains protein 3 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LRIG3	XP_005625618.1
Gallus gallus (chicken)	LRIG3	NP_001186484.1
Drosophila melanogaster (fruit fly)	lbk	NP_611091.2
Xenopus tropicalis (tropical clawed frog)	lrig3	XP_002940426.2
Pan troglodytes (chimpanzee)	LRIG3	XP_001167069.1
Mus musculus (house mouse)	Lrig3	NP_796126.4
Rattus norvegicus (Norway rat)	Lrig3	XP_216905.5
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009688	XP_318747.4
Caenorhabditis elegans (roundworm)	sma-10	NP_499896.1
Bos taurus (cattle)	LRIG3	NP_001192520.1
Danio rerio (zebrafish)	lrig3	NP_001103817.1
Homo sapiens (human)	LRIG3	NP_700356.2
	LRIG3	XP_001116602.1

Gene Ontology
Bibliography

Related articles in PubMed

Cardiac hypertrophy and decreased high-density lipoprotein cholesterol in Lrig3-deficient mice.
Hellstr?m M, Ericsson M, Johansson B, Faraz M, Anderson F, Henriksson R, Nilsson SK, Hedman H
American journal of physiology. Regulatory, integrative and comparative physiology310(11)R1045-52(2016 Jun)

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ
Developmental cell35(5)537-52(2015 Dec)

Radial glia require PDGFD-PDGFR? signalling in human but not mouse neocortex.
Lui JH, Nowakowski TJ, Pollen AA, Javaherian A, Kriegstein AR, Oldham MC
Nature515(7526)264-8(2014 Nov)

In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear.
Del Rio T, Nishitani AM, Yu WM, Goodrich LV
PLoS genetics9(9)e1003824(2013)

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Tamplin OJ, Cox BJ, Rossant J
Developmental biology360(2)415-25(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings in mice complement the human epidemiological results and suggest that Lrig3 may influence heart function and plasma lipid levels in mice and humans.
Title: Cardiac hypertrophy and decreased high-density lipoprotein cholesterol in Lrig3-deficient mice.

Lrig1 and Lrig3 overlap prominently in the developing vestibular apparatus and simultaneous removal of both genes disrupts inner ear morphogenesis.
Title: In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear.

Results suggest that although both Lrig1 and Lrig3 can interact with ErbB receptors in vitro, modulation of Neuregulin signaling is unlikely to contribute to Lrig3-dependent processes of inner ear morphogenesis.
Title: Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis.

mutually antagonistic interactions between Lrig3 and Ntn1 create complementary expression domains that define the future shape of the lateral canal. Removal of one copy of Ntn1 from Lrig3 mutants rescues the circling behavior and the canal malformation.
Title: Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear.

The following Lrig3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrig3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16205	NM_177152.5 Latest version!	Mus musculus leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$657.30 $939.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrig3 ( NM_177152.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_796126.4 Mus musculus leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3), mRNA.

Price & Availability↑

CloneID	OMu16205
Clone ID Related Accession (Same CDS sequence)	NM_177152.5
Accession Version	NM_177152.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3354bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Mus musculus(house mouse)
Product	leucine-rich repeats and immunoglobulin-like domains protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK035166.1, BC065142.1 and AC153489.7. On Jan 6, 2010 this sequence version replaced NM_177152.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY505341.1, BC065142.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTGCTC CCGGACTCCG AGCGGCCACC GCGGCGCTGG GACTGCTGCT GTGCGCGGGG 
CTGGGGCGCG CGGGCCCGGC GGGAAGCGGA GGCCACGGGG CTCCCGGGCA GCTCTTGGAC 
GACGATGCGC AGCGCCCGTG TCCAGCCGCC TGCCACTGCC TCGGGGACCT GCTGGACTGC 
AGCCGGCGGC GGCTGGTTCG CCTTCCCGAT CCTCTCCCGG CCTGGGTCAC ACGGCTGGAC 
CTGAGTCACA ACAGATTATC TTTTATCCAG ACGAGTTCCC TGAGCCACCT TCAAAGCCTT 
CAAGAAGTGA AGCTGAACAA CAATGAATTA GAGACCATTC CAAACCTGGG ATCCATCTCT 
GCAAATATTA GACAGCTATC CTTGGCTGGG AACGCCATCG ACAAAATCCT CCCTGAACAG 
CTGGAAGCCT TTCAGTCCCT TGAGACTTTG GACCTCAGCA ACAATAATAT TTCAGAACTG 
AGAACTGCCT TTCCACCCTT ACAACTCAAG TATCTGTATA TCAATAACAA CCGAGTGTCG 
TCCATGGAAC CAGGGTATTT TGACAATTTG GCGAGCACGC TCCTGGTGCT GAAGCTGAAC 
AGGAACCGCA TCTCAGCCAT CCCTCCCAAG ATGTTTAAAC TGCCTCAGCT GCAGCACCTT 
GAGCTGAACA GAAACAAGAT TAAGAACGTG GATGGACTCA CATTCCAAGG ACTTGGTGCA 
CTGAAGTCTC TGAAAATGCA AAGAAACGGA GTGACAAAGC TGATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAGT CCTGCAGCTG GACCATAACA ACCTAACCGA GATTACCAAA 
GGCTGGCTCT ATGGCTTGTT GATGCTGCGG GAACTTCATC TGAGCCAGAA CGCCATCAAC 
AGGATCAGCC CGGATGCCTG GGAGTTCTGC CAGAAACTCA GTGAGCTAGA CCTGACTTTC 
AACCACTTAT CAAGGCTAGA CGATTCCAGC TTCCTGGGCC TAAGCCTACT AAATGCCCTC 
CACATTGGGA ATAACAAAGT CAGCTACATT GCTGACTGTG CCTTCCGGGG GCTTACCAGT 
TTAAAGACTT TGGATCTGAG GAACAATGAA ATCTCATGGA CCATCGAAGA CATGAGTGGG 
GCATTCTCTG GGCTGGACAG ATTGAGGCAA CTAATTCTCC AGGGAAACCG GATTCGATCT 
ATTACCAAAA AGGCCTTCGC TGGTTTGGAC ACATTGGAAC ACCTGGACCT GAGTGGCAAC 
GCCATCATGT CTCTACAGAG CAATGCGTTT TCCCAAATGA AGAAACTTCA GCAGCTGCAT 
TTAAATACGT CGAGCCTTTT GTGTGACTGC CAGCTGAGAT GGCTCCCACA GTGGGTGGCG 
GAGAACAACT TTCAGAGCTT CGTAAATGCC AGTTGTGCCC ACCCTCAGCT GCTGAAAGGG 
AGGAGCATTT TCACTGTCAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACCGTCC AGCCAGAAAC GCAGTCGGCA ATAAAGGGCT CCGACGTGAG TTTTACCTGC 
TCGGCTGCTA GCAGCAGTGA CTCCCCTATG ACGTTCGCTT GGAAGAAAGA CAACGAAGCG 
CTTCAGGATG CAGAGATGGA GAACTACGCA CACCTGCGGG CCCAGGGAGG CGAGCTGATG 
GAGTATACCA CCATCCTGAG GCTGCGCAAT GTGGAATTCA CCAGCGAAGG GAAGTACCAG 
TGTGTCATCT CCAACCACTT CGGTTCGTCA TACTCCGTCA AAGCCAAGCT CACCATCAAC 
ATGTTGCCTT CCTTTACCAA GACCCCCATG GACCTCACCA TCCGTGCCGG GGCCATGGCC 
CGCCTGGAGT GTGCTGCCGT GGGGCACCCA GCCCCACAGA TAGCCTGGCA GAAGGATGGA 
GGCACGGACT TCCCGGCCGC CCGAGAGAGA CGCATGCACG TGATGCCCGA GGATGACGTC 
TTCTTCATCG TGGACGTGAA GATCGAGGAC ATCGGGGTTT ACAGCTGCAC AGCTCAGAAC 
AGTGCAGGGA GCGTCTCTGC AAACGCAACC CTGACTGTGC TAGAGACGCC GTCATTTTTG 
CGGCCCCTGT TAGACAGAAC CGTCACCAAG GGAGAAACAG CGGTCCTGCA GTGCATTGCT 
GGAGGGAGCC CGCCCCCTCG GCTGAACTGG ACGAAAGATG ACAGCCCTTT GGTGGTGACC 
GAGAGGCACT TTTTTGCAGC AGGCAACCAG CTGCTGATCA TCGTGGACTC GGACGTCAGC 
GACGCCGGGA AATACACGTG TGAGATGTCC AATACCCTTG GCACCGAGAG AGGCAACGTT 
CGCCTCAGTG TGATCCCTAC TCCGACCTGC GACTCCCCTC ACATGACTGC CCCATCGCTG 
GACGGCGATG GATGGGCCAC CGTGGGCGTG GTGATCATAG CTGTGGTTTG CTGTGTGGTG 
GGCACATCCC TCGTGTGGGT GGTCATCATA TACCACACAA GGCGGAGGAA CGAAGACTGC 
AGCATTACCA ACACAGATGA GACCAACTTG CCGGCTGACA TCCCTAGTTA TCTATCATCT 
CAGGGAACAC TAGCTGACAG GCAGGACGGG TACATCTCCT CAGAAAGCGG AAGTCACCAC 
CAGTTCGTGA CTTCTTCGGG AGGCGGATTT TTCTTACCAC AACACGACGG TGCTGGGACC 
TGCCATTTTG ACGACAGCAG TGAGGCTGAT GTGGAAGCCG CTTCTGACCC GTTTCTTTGC 
CCATTCGTGG GCTCCACAGG CCCTGTGTAT CTACAGGGGA ATCTGTACAG CCCAGATCCA 
TTTGAAGTTT ATCTTCCAGG TTGCAGCTCT GACCCGAGGA CCGCTTTAAT GGATCACTGT 
GAGTCCAGCT ACGTGAAGCA GGACCGCTTC TCCTGTGCTC GTCCCTCAGA GGAACCCTGT 
GAACGGAGCC TCAAGAGCAT CCCATGGCCA CATTCCAGAA AGCTCACCGA CTCCACATAT 
CCTCCGAATG AGGGACACAC AGTTCAGACT CTGTGTCTAA ACAAGTCCTC CGTGGATTTC 
AGTACAGGGC CGGAACCAGG ATCGGCTACT TCAAGTAACT CATTCATGGG AACCTTCGGA 
AAACCTCTGA GGAGACCACA CCTGGATGCC TTTTCAAGCT CCGCACAACC GCCAGACTGT 
CAGCCAAGGC CCTGTCACGG GAAATCGCTT TCCTCGCCAG AGCTGGACTC TGAATCAGAA 
GAAAATGACA AAGAAAGGAC AGATTTTCGG GAAGAGAATC ACAGGTGTAC TTATCAACAG 
ATATTCCACA CTTACAGGAC TCCAGATTGC CAGCCTTGTG ATTCAGACAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_796126.4
CDS	258..3611
Translation	MGAPGLRAATAALGLLLCAGLGRAGPAGSGGHGAPGQLLDDDAQRPCPAACHCLGDLLDCSRRRLVRLPDPLPAWVTRLDLSHNRLSFIQTSSLSHLQSLQEVKLNNNELETIPNLGSISANIRQLSLAGNAIDKILPEQLEAFQSLETLDLSNNNISELRTAFPPLQLKYLYINNNRVSSMEPGYFDNLASTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLRNNEISWTIEDMSGAFSGLDRLRQLILQGNRIRSITKKAFAGLDTLEHLDLSGNAIMSLQSNAFSQMKKLQQLHLNTSSLLCDCQLRWLPQWVAENNFQSFVNASCAHPQLLKGRSIFTVSPDGFVCDDFPKPQITVQPETQSAIKGSDVSFTCSAASSSDSPMTFAWKKDNEALQDAEMENYAHLRAQGGELMEYTTILRLRNVEFTSEGKYQCVISNHFGSSYSVKAKLTINMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSVSANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPHMTAPSLDGDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYISSESGSHHQFVTSSGGGFFLPQHDGAGTCHFDDSSEADVEAASDPFLCPFVGSTGPVYLQGNLYSPDPFEVYLPGCSSDPRTALMDHCESSYVKQDRFSCARPSEEPCERSLKSIPWPHSRKLTDSTYPPNEGHTVQTLCLNKSSVDFSTGPEPGSATSSNSFMGTFGKPLRRPHLDAFSSSAQPPDCQPRPCHGKSLSSPELDSESEENDKERTDFREENHRCTYQQIFHTYRTPDCQPCDSDT

Target ORF information:

RefSeq Version	NM_177152.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177152.5

ORF Insert Sequence:

ATGGGTGCTC CCGGACTCCG AGCGGCCACC GCGGCGCTGG GACTGCTGCT GTGCGCGGGG 
CTGGGGCGCG CGGGCCCGGC GGGAAGCGGA GGCCACGGGG CTCCCGGGCA GCTCTTGGAC 
GACGATGCGC AGCGCCCGTG TCCAGCCGCC TGCCACTGCC TCGGGGACCT GCTGGACTGC 
AGCCGGCGGC GGCTGGTTCG CCTTCCCGAT CCTCTCCCGG CCTGGGTCAC ACGGCTGGAC 
CTGAGTCACA ACAGATTATC TTTTATCCAG ACGAGTTCCC TGAGCCACCT TCAAAGCCTT 
CAAGAAGTGA AGCTGAACAA CAATGAATTA GAGACCATTC CAAACCTGGG ATCCATCTCT 
GCAAATATTA GACAGCTATC CTTGGCTGGG AACGCCATCG ACAAAATCCT CCCTGAACAG 
CTGGAAGCCT TTCAGTCCCT TGAGACTTTG GACCTCAGCA ACAATAATAT TTCAGAACTG 
AGAACTGCCT TTCCACCCTT ACAACTCAAG TATCTGTATA TCAATAACAA CCGAGTGTCG 
TCCATGGAAC CAGGGTATTT TGACAATTTG GCGAGCACGC TCCTGGTGCT GAAGCTGAAC 
AGGAACCGCA TCTCAGCCAT CCCTCCCAAG ATGTTTAAAC TGCCTCAGCT GCAGCACCTT 
GAGCTGAACA GAAACAAGAT TAAGAACGTG GATGGACTCA CATTCCAAGG ACTTGGTGCA 
CTGAAGTCTC TGAAAATGCA AAGAAACGGA GTGACAAAGC TGATGGATGG AGCTTTTTGG 
GGGCTGAGCA ACATGGAAGT CCTGCAGCTG GACCATAACA ACCTAACCGA GATTACCAAA 
GGCTGGCTCT ATGGCTTGTT GATGCTGCGG GAACTTCATC TGAGCCAGAA CGCCATCAAC 
AGGATCAGCC CGGATGCCTG GGAGTTCTGC CAGAAACTCA GTGAGCTAGA CCTGACTTTC 
AACCACTTAT CAAGGCTAGA CGATTCCAGC TTCCTGGGCC TAAGCCTACT AAATGCCCTC 
CACATTGGGA ATAACAAAGT CAGCTACATT GCTGACTGTG CCTTCCGGGG GCTTACCAGT 
TTAAAGACTT TGGATCTGAG GAACAATGAA ATCTCATGGA CCATCGAAGA CATGAGTGGG 
GCATTCTCTG GGCTGGACAG ATTGAGGCAA CTAATTCTCC AGGGAAACCG GATTCGATCT 
ATTACCAAAA AGGCCTTCGC TGGTTTGGAC ACATTGGAAC ACCTGGACCT GAGTGGCAAC 
GCCATCATGT CTCTACAGAG CAATGCGTTT TCCCAAATGA AGAAACTTCA GCAGCTGCAT 
TTAAATACGT CGAGCCTTTT GTGTGACTGC CAGCTGAGAT GGCTCCCACA GTGGGTGGCG 
GAGAACAACT TTCAGAGCTT CGTAAATGCC AGTTGTGCCC ACCCTCAGCT GCTGAAAGGG 
AGGAGCATTT TCACTGTCAG CCCAGATGGC TTTGTGTGTG ATGATTTTCC CAAACCCCAG 
ATCACCGTCC AGCCAGAAAC GCAGTCGGCA ATAAAGGGCT CCGACGTGAG TTTTACCTGC 
TCGGCTGCTA GCAGCAGTGA CTCCCCTATG ACGTTCGCTT GGAAGAAAGA CAACGAAGCG 
CTTCAGGATG CAGAGATGGA GAACTACGCA CACCTGCGGG CCCAGGGAGG CGAGCTGATG 
GAGTATACCA CCATCCTGAG GCTGCGCAAT GTGGAATTCA CCAGCGAAGG GAAGTACCAG 
TGTGTCATCT CCAACCACTT CGGTTCGTCA TACTCCGTCA AAGCCAAGCT CACCATCAAC 
ATGTTGCCTT CCTTTACCAA GACCCCCATG GACCTCACCA TCCGTGCCGG GGCCATGGCC 
CGCCTGGAGT GTGCTGCCGT GGGGCACCCA GCCCCACAGA TAGCCTGGCA GAAGGATGGA 
GGCACGGACT TCCCGGCCGC CCGAGAGAGA CGCATGCACG TGATGCCCGA GGATGACGTC 
TTCTTCATCG TGGACGTGAA GATCGAGGAC ATCGGGGTTT ACAGCTGCAC AGCTCAGAAC 
AGTGCAGGGA GCGTCTCTGC AAACGCAACC CTGACTGTGC TAGAGACGCC GTCATTTTTG 
CGGCCCCTGT TAGACAGAAC CGTCACCAAG GGAGAAACAG CGGTCCTGCA GTGCATTGCT 
GGAGGGAGCC CGCCCCCTCG GCTGAACTGG ACGAAAGATG ACAGCCCTTT GGTGGTGACC 
GAGAGGCACT TTTTTGCAGC AGGCAACCAG CTGCTGATCA TCGTGGACTC GGACGTCAGC 
GACGCCGGGA AATACACGTG TGAGATGTCC AATACCCTTG GCACCGAGAG AGGCAACGTT 
CGCCTCAGTG TGATCCCTAC TCCGACCTGC GACTCCCCTC ACATGACTGC CCCATCGCTG 
GACGGCGATG GATGGGCCAC CGTGGGCGTG GTGATCATAG CTGTGGTTTG CTGTGTGGTG 
GGCACATCCC TCGTGTGGGT GGTCATCATA TACCACACAA GGCGGAGGAA CGAAGACTGC 
AGCATTACCA ACACAGATGA GACCAACTTG CCGGCTGACA TCCCTAGTTA TCTATCATCT 
CAGGGAACAC TAGCTGACAG GCAGGACGGG TACATCTCCT CAGAAAGCGG AAGTCACCAC 
CAGTTCGTGA CTTCTTCGGG AGGCGGATTT TTCTTACCAC AACACGACGG TGCTGGGACC 
TGCCATTTTG ACGACAGCAG TGAGGCTGAT GTGGAAGCCG CTTCTGACCC GTTTCTTTGC 
CCATTCGTGG GCTCCACAGG CCCTGTGTAT CTACAGGGGA ATCTGTACAG CCCAGATCCA 
TTTGAAGTTT ATCTTCCAGG TTGCAGCTCT GACCCGAGGA CCGCTTTAAT GGATCACTGT 
GAGTCCAGCT ACGTGAAGCA GGACCGCTTC TCCTGTGCTC GTCCCTCAGA GGAACCCTGT 
GAACGGAGCC TCAAGAGCAT CCCATGGCCA CATTCCAGAA AGCTCACCGA CTCCACATAT 
CCTCCGAATG AGGGACACAC AGTTCAGACT CTGTGTCTAA ACAAGTCCTC CGTGGATTTC 
AGTACAGGGC CGGAACCAGG ATCGGCTACT TCAAGTAACT CATTCATGGG AACCTTCGGA 
AAACCTCTGA GGAGACCACA CCTGGATGCC TTTTCAAGCT CCGCACAACC GCCAGACTGT 
CAGCCAAGGC CCTGTCACGG GAAATCGCTT TCCTCGCCAG AGCTGGACTC TGAATCAGAA 
GAAAATGACA AAGAAAGGAC AGATTTTCGG GAAGAGAATC ACAGGTGTAC TTATCAACAG 
ATATTCCACA CTTACAGGAC TCCAGATTGC CAGCCTTGTG ATTCAGACAC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cardiac hypertrophy and decreased high-density lipoprotein cholesterol in Lrig3-deficient mice.
American journal of physiology. Regulatory, integrative and comparative physiology310(11)R1045-52(2016 Jun)
Hellstr?m M,Ericsson M,Johansson B,Faraz M,Anderson F,Henriksson R,Nilsson SK,Hedman H

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
Developmental cell35(5)537-52(2015 Dec)
van Erp S,van den Heuvel DM,Fujita Y,Robinson RA,Hellemons AJ,Adolfs Y,Van Battum EY,Blokhuis AM,Kuijpers M,Demmers JA,Hedman H,Hoogenraad CC,Siebold C,Yamashita T,Pasterkamp RJ

Radial glia require PDGFD-PDGFR? signalling in human but not mouse neocortex.
Nature515(7526)264-8(2014 Nov)
Lui JH,Nowakowski TJ,Pollen AA,Javaherian A,Kriegstein AR,Oldham MC

In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear.
PLoS genetics9(9)e1003824(2013)
Del Rio T,Nishitani AM,Yu WM,Goodrich LV

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Developmental biology360(2)415-25(2011 Dec)
Tamplin OJ,Cox BJ,Rossant J

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Lrig3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報