Mpzl3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mpzl3
Entrez Gene ID	319742
Full Name	myelin protein zero-like 3
Synonyms	5430427F17Rik,A530065I17Rik,rc
General protein information	Preferred Names myelin protein zero-like 3 Names myelin protein zero-like protein 3 Ig-like domain-containing protein UNQ2966
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9 A5.2\|9 24.84 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001093749.3	NP_001087218.1	myelin protein zero-like protein 3 precursor
NM_001093749.2	NP_001087218.1	myelin protein zero-like protein 3 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MPZL3	NP_001091520.1
Mus musculus (house mouse)	Mpzl3	NP_001087218.1
Rattus norvegicus (Norway rat)	Mpzl3	NP_001102230.1
Pan troglodytes (chimpanzee)	MPZL3	XP_003313381.1
	MPZL3	XP_001096649.1
Gallus gallus (chicken)	MPZL3	NP_001239214.1
Xenopus tropicalis (tropical clawed frog)	mpzl3	NP_001120135.1
Homo sapiens (human)	MPZL3	NP_938016.1
Canis lupus familiaris (dog)	MPZL3	XP_546503.3

Gene Ontology
Bibliography

Related articles in PubMed

Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.
Inoue SI, Takahara S, Yoshikawa T, Niihori T, Yanai K, Matsubara Y, Aoki Y
Human molecular genetics26(23)4715-4727(2017 Dec)

Loss of MPZL3 function causes seborrhoeic dermatitis-like phenotype in mice.
Wikramanayake TC, Borda LJ, Kirsner RS, Wang Y, Duffort S, Reyes-Capo A, Barsam A, Urbieta M, Perez VL
Experimental dermatology26(8)736-738(2017 Aug)

Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots.
Leiva AG, Chen AL, Devarajan P, Chen Z, Damanpour S, Hall JA, Bianco AC, Li J, Badiavas EV, Zaias J, Miteva M, Romanelli P, Nouri K, Cao Wikramanayake T
The Journal of investigative dermatology134(7)1817-1827(2014 Jul)

Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis.
Czyzyk TA, Andrews JL, Coskun T, Wade MR, Hawkins ED, Lockwood JF, Varga G, Sahr AE, Chen Y, Brozinick JT, Kikly K, Statnick MA
American journal of physiology. Endocrinology and metabolism305(2)E282-92(2013 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mpzl3 has a novel physiological role in controlling body weight regulation, energy expenditure, glycemic control, and hepatic triglyceride synthesis in mice
Title: Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis.

novel gene encoding a predicted adhesion protein whose mutation in the rc/rc mice likely caused the rc phenotype
Title: Mutation in Mpzl3, a novel [corrected] gene encoding a predicted [corrected] adhesion protein, in the rough coat (rc) mice with severe skin and hair abnormalities.

The following Mpzl3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mpzl3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu14132	NM_001093749.3 Latest version!	Mus musculus myelin protein zero-like 3 (Mpzl3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
View Old Accession Versions >>
OMu14132	NM_001093749.2	Mus musculus myelin protein zero-like 3 (Mpzl3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mpzl3 ( NM_001093749.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001087218.1 Mus musculus myelin protein zero-like 3 (Mpzl3), mRNA.

Price & Availability↑

CloneID	OMu14132
Clone ID Related Accession (Same CDS sequence)	NM_001093749.3 , NM_001093749.2
Accession Version	NM_001093749.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Mus musculus(house mouse)
Product	myelin protein zero-like protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC122305.4 and EF102773.1. On Feb 13, 2018 this sequence version replaced NM_001093749.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EF102773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCTGG CAAGAGGAAC AGTAGGAGGC CGTGGCTGCG CTCTCTTTCC ACTGCTGAGC 
ATCCTAGTCG TCCAGGGTGC GCGTATCGTC CTCTCCTTGG AGATAAGTGC CGATGCTCAC 
GTCCGAGGCT ATGTGGGAGA GAAGATCAAG TTGAAATGCA CCTTCAAGTC ATCTTCAGAT 
GTCACTGACA AGCTGACCAT AGACTGGACA TACCGCCCTC CCAGCAGCAG CCGCACAGAG 
TCTATTTTTC ACTATCAGTC TTTCCAGTAC CCGACCACAG CGGGCACATT CCGAGACCGG 
ATCTCCTGGG CCGGAAATGT CTACAAAGGG GATGCGTCCA TCAGTATCAG CAACCCCACT 
CTAAAGGACA ATGGGACGTT CAGCTGTGCT GTGAAGAACC CTCCAGACGT GTACCACAAT 
ATCCCCCTAA CAGAGCTCAC GGTCACAGAA AGGGGGTTCG GCACCATGCT GTCTTCTGTG 
GCCCTTCTCT CCATCCTCGT CTTCGTCCCC TCAGCAGTGG TGGTCATTCT GCTGCTGGTG 
CGAATGGGGA GGAAGGCAAC AGGGGTGCAG AAGAGGAGCA GGTCTGGCTA TAAGAAGTCT 
TCCATTGAAG TTTCCGATGA CACTGACCAG GAGGACAGCA ATGACTGCAT GACGAGGCTT 
TGTGTCCGCT GTGCAGAGTG TCTGGATTCA GACTACGAAG AAGAGGCGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001087218.1
CDS	63..776
Translation	MQLARGTVGGRGCALFPLLSILVVQGARIVLSLEISADAHVRGYVGEKIKLKCTFKSSSDVTDKLTIDWTYRPPSSSRTESIFHYQSFQYPTTAGTFRDRISWAGNVYKGDASISISNPTLKDNGTFSCAVKNPPDVYHNIPLTELTVTERGFGTMLSSVALLSILVFVPSAVVVILLLVRMGRKATGVQKRSRSGYKKSSIEVSDDTDQEDSNDCMTRLCVRCAECLDSDYEEEAY

Target ORF information:

RefSeq Version	NM_001093749.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus myelin protein zero-like 3 (Mpzl3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001093749.3

ORF Insert Sequence:

ATGCAGCTGG CAAGAGGAAC AGTAGGAGGC CGTGGCTGCG CTCTCTTTCC ACTGCTGAGC 
ATCCTAGTCG TCCAGGGTGC GCGTATCGTC CTCTCCTTGG AGATAAGTGC CGATGCTCAC 
GTCCGAGGCT ATGTGGGAGA GAAGATCAAG TTGAAATGCA CCTTCAAGTC ATCTTCAGAT 
GTCACTGACA AGCTGACCAT AGACTGGACA TACCGCCCTC CCAGCAGCAG CCGCACAGAG 
TCTATTTTTC ACTATCAGTC TTTCCAGTAC CCGACCACAG CGGGCACATT CCGAGACCGG 
ATCTCCTGGG CCGGAAATGT CTACAAAGGG GATGCGTCCA TCAGTATCAG CAACCCCACT 
CTAAAGGACA ATGGGACGTT CAGCTGTGCT GTGAAGAACC CTCCAGACGT GTACCACAAT 
ATCCCCCTAA CAGAGCTCAC GGTCACAGAA AGGGGGTTCG GCACCATGCT GTCTTCTGTG 
GCCCTTCTCT CCATCCTCGT CTTCGTCCCC TCAGCAGTGG TGGTCATTCT GCTGCTGGTG 
CGAATGGGGA GGAAGGCAAC AGGGGTGCAG AAGAGGAGCA GGTCTGGCTA TAAGAAGTCT 
TCCATTGAAG TTTCCGATGA CACTGACCAG GAGGACAGCA ATGACTGCAT GACGAGGCTT 
TGTGTCCGCT GTGCAGAGTG TCTGGATTCA GACTACGAAG AAGAGGCGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mpzl3 ( NM_001093749.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001087218.1 Mus musculus myelin protein zero-like 3 (Mpzl3), mRNA.

Price & Availability↑

CloneID	OMu14132
Clone ID Related Accession (Same CDS sequence)	NM_001093749.3 , NM_001093749.2
Accession Version	NM_001093749.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-01
Organism	Mus musculus(house mouse)
Product	myelin protein zero-like protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC122305.4 and EF102773.1. On Nov 13, 2013 this sequence version replaced NM_001093749.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EF102773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCTGG CAAGAGGAAC AGTAGGAGGC CGTGGCTGCG CTCTCTTTCC ACTGCTGAGC 
ATCCTAGTCG TCCAGGGTGC GCGTATCGTC CTCTCCTTGG AGATAAGTGC CGATGCTCAC 
GTCCGAGGCT ATGTGGGAGA GAAGATCAAG TTGAAATGCA CCTTCAAGTC ATCTTCAGAT 
GTCACTGACA AGCTGACCAT AGACTGGACA TACCGCCCTC CCAGCAGCAG CCGCACAGAG 
TCTATTTTTC ACTATCAGTC TTTCCAGTAC CCGACCACAG CGGGCACATT CCGAGACCGG 
ATCTCCTGGG CCGGAAATGT CTACAAAGGG GATGCGTCCA TCAGTATCAG CAACCCCACT 
CTAAAGGACA ATGGGACGTT CAGCTGTGCT GTGAAGAACC CTCCAGACGT GTACCACAAT 
ATCCCCCTAA CAGAGCTCAC GGTCACAGAA AGGGGGTTCG GCACCATGCT GTCTTCTGTG 
GCCCTTCTCT CCATCCTCGT CTTCGTCCCC TCAGCAGTGG TGGTCATTCT GCTGCTGGTG 
CGAATGGGGA GGAAGGCAAC AGGGGTGCAG AAGAGGAGCA GGTCTGGCTA TAAGAAGTCT 
TCCATTGAAG TTTCCGATGA CACTGACCAG GAGGACAGCA ATGACTGCAT GACGAGGCTT 
TGTGTCCGCT GTGCAGAGTG TCTGGATTCA GACTACGAAG AAGAGGCGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001087218.1
CDS	63..776
Translation	MQLARGTVGGRGCALFPLLSILVVQGARIVLSLEISADAHVRGYVGEKIKLKCTFKSSSDVTDKLTIDWTYRPPSSSRTESIFHYQSFQYPTTAGTFRDRISWAGNVYKGDASISISNPTLKDNGTFSCAVKNPPDVYHNIPLTELTVTERGFGTMLSSVALLSILVFVPSAVVVILLLVRMGRKATGVQKRSRSGYKKSSIEVSDDTDQEDSNDCMTRLCVRCAECLDSDYEEEAY

Target ORF information:

RefSeq Version	NM_001093749.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus myelin protein zero-like 3 (Mpzl3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001093749.2

ORF Insert Sequence:

ATGCAGCTGG CAAGAGGAAC AGTAGGAGGC CGTGGCTGCG CTCTCTTTCC ACTGCTGAGC 
ATCCTAGTCG TCCAGGGTGC GCGTATCGTC CTCTCCTTGG AGATAAGTGC CGATGCTCAC 
GTCCGAGGCT ATGTGGGAGA GAAGATCAAG TTGAAATGCA CCTTCAAGTC ATCTTCAGAT 
GTCACTGACA AGCTGACCAT AGACTGGACA TACCGCCCTC CCAGCAGCAG CCGCACAGAG 
TCTATTTTTC ACTATCAGTC TTTCCAGTAC CCGACCACAG CGGGCACATT CCGAGACCGG 
ATCTCCTGGG CCGGAAATGT CTACAAAGGG GATGCGTCCA TCAGTATCAG CAACCCCACT 
CTAAAGGACA ATGGGACGTT CAGCTGTGCT GTGAAGAACC CTCCAGACGT GTACCACAAT 
ATCCCCCTAA CAGAGCTCAC GGTCACAGAA AGGGGGTTCG GCACCATGCT GTCTTCTGTG 
GCCCTTCTCT CCATCCTCGT CTTCGTCCCC TCAGCAGTGG TGGTCATTCT GCTGCTGGTG 
CGAATGGGGA GGAAGGCAAC AGGGGTGCAG AAGAGGAGCA GGTCTGGCTA TAAGAAGTCT 
TCCATTGAAG TTTCCGATGA CACTGACCAG GAGGACAGCA ATGACTGCAT GACGAGGCTT 
TGTGTCCGCT GTGCAGAGTG TCTGGATTCA GACTACGAAG AAGAGGCGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.
Human molecular genetics26(23)4715-4727(2017 Dec)
Inoue SI,Takahara S,Yoshikawa T,Niihori T,Yanai K,Matsubara Y,Aoki Y

Loss of MPZL3 function causes seborrhoeic dermatitis-like phenotype in mice.
Experimental dermatology26(8)736-738(2017 Aug)
Wikramanayake TC,Borda LJ,Kirsner RS,Wang Y,Duffort S,Reyes-Capo A,Barsam A,Urbieta M,Perez VL

Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots.
The Journal of investigative dermatology134(7)1817-1827(2014 Jul)
Leiva AG,Chen AL,Devarajan P,Chen Z,Damanpour S,Hall JA,Bianco AC,Li J,Badiavas EV,Zaias J,Miteva M,Romanelli P,Nouri K,Cao Wikramanayake T

Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis.
American journal of physiology. Endocrinology and metabolism305(2)E282-92(2013 Jul)
Czyzyk TA,Andrews JL,Coskun T,Wade MR,Hawkins ED,Lockwood JF,Varga G,Sahr AE,Chen Y,Brozinick JT,Kikly K,Statnick MA

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Mpzl3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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