Lig4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lig4
Entrez Gene ID	319583
Full Name	ligase IV, DNA, ATP-dependent
Synonyms	5830471N16Rik,tiny
General protein information	Preferred Names ligase IV, DNA, ATP-dependent Names DNA ligase 4 DNA ligase IV polydeoxyribonucleotide synthase [ATP] 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 A1.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_176953.3	NP_795927.2	DNA ligase 4
NM_001377042.1	NP_001363971.1	DNA ligase 4
XM_017312854.1	XP_017168343.1	DNA ligase 4 isoform X1
NM_176953.4	NP_795927.2	DNA ligase 4

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Lig4	NP_001099565.1
Drosophila melanogaster (fruit fly)	Lig4	NP_572907.1
Magnaporthe oryzae (rice blast fungus)	MGG_12899	XP_003712808.1
Bos taurus (cattle)	LIG4	NP_001178055.1
Saccharomyces cerevisiae (baker's yeast)	DNL4	NP_014647.1
Eremothecium gossypii	AGOS_ACR008W	NP_983411.1
Gallus gallus (chicken)	LIG4	NP_001025987.1
Kluyveromyces lactis	KLLA0D01089g	XP_453119.1
Neurospora crassa	NCU06264	XP_962868.1
Mus musculus (house mouse)	Lig4	NP_795927.2
Danio rerio (zebrafish)	lig4	NP_001096593.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000623	XP_310455.4
Arabidopsis thaliana (thale cress)	ATLIG4	NP_568851.2
Homo sapiens (human)	LIG4	NP_001091738.1
Pan troglodytes (chimpanzee)	LIG4	XP_003314254.1
Canis lupus familiaris (dog)	LIG4	XP_005634152.1
Schizosaccharomyces pombe (fission yeast)	lig4	NP_587888.2
Xenopus tropicalis (tropical clawed frog)	lig4	NP_001016981.1

Gene Ontology
Bibliography

Related articles in PubMed

Synthetic lethality between PAXX and XLF in mammalian development.
Balmus G, Barros AC, Wijnhoven PW, Lescale C, Hasse HL, Boroviak K, le Sage C, Doe B, Speak AO, Galli A, Jacobsen M, Deriano L, Adams DJ, Blackford AN, Jackson SP
Genes & development30(19)2152-2157(2016 Oct)

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.
Dooley J, Tian L, Schonefeldt S, Delghingaro-Augusto V, Garcia-Perez JE, Pasciuto E, Di Marino D, Carr EJ, Oskolkov N, Lyssenko V, Franckaert D, Lagou V, Overbergh L, Vandenbussche J, Allemeersch J, Chabot-Roy G, Dahlstrom JE, Laybutt DR, Petrovsky N, Socha L, Gevaert K, Jetten AM, Lambrechts D, Linterman MA, Goodnow CC, Nolan CJ, Lesage S, Schlenner SM, Liston A
Nature genetics48(5)519-27(2016 05)

HELB Is a Feedback Inhibitor of DNA End Resection.
Tk?? J, Xu G, Adhikary H, Young JTF, Gallo D, Escribano-D?az C, Krietsch J, Orthwein A, Munro M, Sol W, Al-Hakim A, Lin ZY, Jonkers J, Borst P, Brown GW, Gingras AC, Rottenberg S, Masson JY, Durocher D
Molecular cell61(3)405-418(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data firmly demonstrate Lig4(R278H) activity renders nonhomologous end-joining (NHEJ) DNA repair to be more error-prone, and predict increased error-prone NHEJ and A-EJ suppression as the cause of defective B lymphopoiesis in Lig4 patients.
Title: The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.

To promote homology-directed r at the expense of nonhomologous end joining , we targeted DNA ligase IV, a key enzyme in the NHEJ pathway, using the inhibitor Scr7. This approach should be applicable to other customizable endonucleases
Title: Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.

Lig4 and XRCC1 double-deficient cells switch as efficiently as Lig4-deficient cells, clearly indicating that XRCC1 is dispensable for A-EJ in CH12F3 cells during class switch recombination
Title: X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining.

These studies provide insight into the interplay between DNA damage responses in the developing brain and the DNA ligase IV plat the role in repairing endogenously arising DNA double-strand breaks.
Title: Requirement for DNA ligase IV during embryonic neuronal development.

Lig4-deficient B cells have reduced, but still substantial, immunoglobulins class switch recombination
Title: Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

The following Lig4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lig4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05774	XM_017312854.1 Latest version!	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$531.30 $759.00
OMu05774	NM_176953.4 Latest version!	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu05774	NM_001377042.1 Latest version!	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OMu05774	NM_176953.3	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$531.30 $759.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lig4 ( NM_176953.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_795927.2 Mus musculus ligase IV, DNA, ATP-dependent (Lig4), mRNA.

Price & Availability↑

CloneID	OMu05774
Clone ID Related Accession (Same CDS sequence)	NM_176953.3 , NM_001377042.1 , XM_017312854.1 , NM_176953.4
Accession Version	NM_176953.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-19
Organism	Mus musculus(house mouse)
Product	DNA ligase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ088420.1, AK030966.1 and AC138397.4. On Jan 12, 2006 this sequence version replaced NM_176953.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148081.1, SRR1660821.21429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_795927.2
CDS	323..3058
Translation	MASSQTSQTVAAHVPFADLCSTLERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNRKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDAQKLLNYRTPSGARTDAGDFAMIAYFVLKPRCLQKGSLTIQQVNELLDLVASNNSGKKKDLVKKSLLQLITQSSALEQKWLIRMIIKDLKLGISQQTIFSIFHNDAVELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAVADVERVEKDMKQQSFYIETKLDGERMQMHKDGALYRYFSRNGYNYTDQFGESPQEGSLTPFIHNAFGTDVQACILDGEMMAYNPTTQTFMQKGVKFDIKRMVEDSGLQTCYSVFDVLMVNKKKLGRETLRKRYEILSSTFTPIQGRIEIVQKTQAHTKKEVVDALNDAIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYVSGLMDELDVLIVGGYWGKGSRGGMMSHFLCAVAETPPPGDRPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILCGTEKPEVYIEPQNSVIVQIKAAEIVPSDMYKTGSTLRFPRIEKIRDDKEWHECMTLGDLEQLRGKASGKLATKHLHVGDDDEPREKRRKPISKTKKAIRIIEHLKAPNLSNVNKVSNVFEDVEFCVMSGLDGYPKADLENRIAEFGGYIVQNPGPDTYCVIAGSENVRVKNIISSDKNDVVKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDTDLDQLKEVFLGIKPSEQQTPEEMAPVIADLECRYSWDHSPLSMFRHYTIYLDLYAVINDLSSRIEATRLGITALELRFHGAKVVSCLSEGVSHVIIGEDQRRVTDFKIFRRMLKKKFKILQESWVSDSVDKGELQEENQYLL

Target ORF information:

RefSeq Version	NM_176953.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176953.3

ORF Insert Sequence:

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lig4 ( XM_017312854.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017168343.1 Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu05774
Clone ID Related Accession (Same CDS sequence)	NM_176953.3 , NM_001377042.1 , XM_017312854.1 , NM_176953.4
Accession Version	XM_017312854.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	DNA ligase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017168343.1
CDS	199..2934
Translation	MASSQTSQTVAAHVPFADLCSTLERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNRKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDAQKLLNYRTPSGARTDAGDFAMIAYFVLKPRCLQKGSLTIQQVNELLDLVASNNSGKKKDLVKKSLLQLITQSSALEQKWLIRMIIKDLKLGISQQTIFSIFHNDAVELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAVADVERVEKDMKQQSFYIETKLDGERMQMHKDGALYRYFSRNGYNYTDQFGESPQEGSLTPFIHNAFGTDVQACILDGEMMAYNPTTQTFMQKGVKFDIKRMVEDSGLQTCYSVFDVLMVNKKKLGRETLRKRYEILSSTFTPIQGRIEIVQKTQAHTKKEVVDALNDAIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYVSGLMDELDVLIVGGYWGKGSRGGMMSHFLCAVAETPPPGDRPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILCGTEKPEVYIEPQNSVIVQIKAAEIVPSDMYKTGSTLRFPRIEKIRDDKEWHECMTLGDLEQLRGKASGKLATKHLHVGDDDEPREKRRKPISKTKKAIRIIEHLKAPNLSNVNKVSNVFEDVEFCVMSGLDGYPKADLENRIAEFGGYIVQNPGPDTYCVIAGSENVRVKNIISSDKNDVVKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDTDLDQLKEVFLGIKPSEQQTPEEMAPVIADLECRYSWDHSPLSMFRHYTIYLDLYAVINDLSSRIEATRLGITALELRFHGAKVVSCLSEGVSHVIIGEDQRRVTDFKIFRRMLKKKFKILQESWVSDSVDKGELQEENQYLL

Target ORF information:

RefSeq Version	XM_017312854.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017312854.1

ORF Insert Sequence:

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lig4 ( NM_001377042.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001363971.1 Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu05774
Clone ID Related Accession (Same CDS sequence)	NM_176953.3 , NM_001377042.1 , XM_017312854.1 , NM_176953.4
Accession Version	NM_001377042.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-10
Organism	Mus musculus(house mouse)
Product	DNA ligase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK030029.1 and AC138397.4. On Dec 10, 2019 this sequence version replaced XM_017312854.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK030029.1, BB616463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164133 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001363971.1
CDS	198..2933
Translation	MASSQTSQTVAAHVPFADLCSTLERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNRKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDAQKLLNYRTPSGARTDAGDFAMIAYFVLKPRCLQKGSLTIQQVNELLDLVASNNSGKKKDLVKKSLLQLITQSSALEQKWLIRMIIKDLKLGISQQTIFSIFHNDAVELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAVADVERVEKDMKQQSFYIETKLDGERMQMHKDGALYRYFSRNGYNYTDQFGESPQEGSLTPFIHNAFGTDVQACILDGEMMAYNPTTQTFMQKGVKFDIKRMVEDSGLQTCYSVFDVLMVNKKKLGRETLRKRYEILSSTFTPIQGRIEIVQKTQAHTKKEVVDALNDAIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYVSGLMDELDVLIVGGYWGKGSRGGMMSHFLCAVAETPPPGDRPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILCGTEKPEVYIEPQNSVIVQIKAAEIVPSDMYKTGSTLRFPRIEKIRDDKEWHECMTLGDLEQLRGKASGKLATKHLHVGDDDEPREKRRKPISKTKKAIRIIEHLKAPNLSNVNKVSNVFEDVEFCVMSGLDGYPKADLENRIAEFGGYIVQNPGPDTYCVIAGSENVRVKNIISSDKNDVVKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDTDLDQLKEVFLGIKPSEQQTPEEMAPVIADLECRYSWDHSPLSMFRHYTIYLDLYAVINDLSSRIEATRLGITALELRFHGAKVVSCLSEGVSHVIIGEDQRRVTDFKIFRRMLKKKFKILQESWVSDSVDKGELQEENQYLL

Target ORF information:

RefSeq Version	NM_001377042.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001377042.1

ORF Insert Sequence:

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lig4 ( NM_176953.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_795927.2 Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu05774
Clone ID Related Accession (Same CDS sequence)	NM_176953.3 , NM_001377042.1 , XM_017312854.1 , NM_176953.4
Accession Version	NM_176953.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-11
Organism	Mus musculus(house mouse)
Product	DNA ligase 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ088420.1, AK030966.1 and AC138397.4. On Dec 10, 2019 this sequence version replaced NM_176953.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK148081.1, AK083353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_795927.2
CDS	311..3046
Translation	MASSQTSQTVAAHVPFADLCSTLERIQKGKDRAEKIRHFKEFLDSWRKFHDALHKNRKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPREGKDAQKLLNYRTPSGARTDAGDFAMIAYFVLKPRCLQKGSLTIQQVNELLDLVASNNSGKKKDLVKKSLLQLITQSSALEQKWLIRMIIKDLKLGISQQTIFSIFHNDAVELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAVADVERVEKDMKQQSFYIETKLDGERMQMHKDGALYRYFSRNGYNYTDQFGESPQEGSLTPFIHNAFGTDVQACILDGEMMAYNPTTQTFMQKGVKFDIKRMVEDSGLQTCYSVFDVLMVNKKKLGRETLRKRYEILSSTFTPIQGRIEIVQKTQAHTKKEVVDALNDAIDKREEGIMVKHPLSIYKPDKRGEGWLKIKPEYVSGLMDELDVLIVGGYWGKGSRGGMMSHFLCAVAETPPPGDRPSVFHTLCRVGSGYTMKELYDLGLKLAKYWKPFHKKSPPSSILCGTEKPEVYIEPQNSVIVQIKAAEIVPSDMYKTGSTLRFPRIEKIRDDKEWHECMTLGDLEQLRGKASGKLATKHLHVGDDDEPREKRRKPISKTKKAIRIIEHLKAPNLSNVNKVSNVFEDVEFCVMSGLDGYPKADLENRIAEFGGYIVQNPGPDTYCVIAGSENVRVKNIISSDKNDVVKPEWLLECFKTKTCVPWQPRFMIHMCPSTKQHFAREYDCYGDSYFVDTDLDQLKEVFLGIKPSEQQTPEEMAPVIADLECRYSWDHSPLSMFRHYTIYLDLYAVINDLSSRIEATRLGITALELRFHGAKVVSCLSEGVSHVIIGEDQRRVTDFKIFRRMLKKKFKILQESWVSDSVDKGELQEENQYLL

Target ORF information:

RefSeq Version	NM_176953.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ligase IV, DNA, ATP-dependent (Lig4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176953.4

ORF Insert Sequence:

ATGGCTTCCT CACAAACTTC ACAAACTGTT GCAGCTCATG TCCCCTTTGC AGACTTATGT 
TCCACACTAG AACGGATACA GAAAGGTAAA GACCGTGCAG AAAAAATCAG GCACTTCAAG 
GAGTTTTTGG ATTCGTGGAG AAAATTTCAT GATGCCCTTC ATAAGAACAG AAAGGACGTT 
ACAGACTCTT TTTACCCTGC AATGAGACTC ATTCTCCCCC AGTTAGAAAG AGAGAGGATG 
GCTTATGGAA TCAAAGAAAC CATGCTCGCT AAGCTCTACA TCGAATTGCT GAACTTACCA 
CGAGAAGGCA AGGATGCCCA GAAGCTCCTC AATTACCGAA CCCCCAGTGG AGCTCGCACG 
GATGCTGGGG ACTTTGCCAT GATTGCATAC TTTGTTTTGA AGCCAAGGTG CTTACAGAAA 
GGAAGCTTAA CCATACAGCA GGTAAATGAA CTCTTAGACT TAGTTGCCAG CAATAACTCT 
GGCAAAAAAA AAGACCTAGT GAAAAAGAGC CTTCTTCAGT TAATAACCCA GAGTTCAGCA 
CTGGAGCAAA AATGGCTGAT TCGCATGATT ATCAAAGACT TAAAGCTTGG CATCAGTCAG 
CAAACAATAT TTTCCATTTT CCACAATGAT GCAGTTGAGT TGCACAACGT CACCACAGAT 
CTGGAAAAGG TCTGCAGGCA GCTGCATGAC CCCTCTGTAG GGCTTAGTGA CATCTCTATC 
ACTCTGTTTT CTGCCTTTAA GCCAATGCTA GCTGCTGTAG CAGACGTGGA GCGTGTGGAG 
AAGGACATGA AGCAGCAGAG TTTCTACATC GAAACTAAGC TTGATGGTGA GCGCATGCAG 
ATGCACAAAG ATGGCGCGCT GTACCGGTAC TTCTCCAGAA ACGGTTACAA CTATACCGAC 
CAGTTTGGTG AATCTCCACA GGAAGGCTCT CTCACCCCAT TTATTCACAA TGCGTTCGGG 
ACAGATGTGC AAGCGTGCAT CCTTGACGGT GAGATGATGG CCTACAACCC AACAACACAG 
ACTTTCATGC AGAAGGGGGT CAAGTTTGAT ATCAAAAGGA TGGTGGAAGA TTCTGGCCTA 
CAGACTTGTT ACTCTGTTTT TGACGTACTG ATGGTTAATA AGAAGAAGCT AGGGCGCGAG 
ACTCTTAGGA AGAGGTATGA GATCCTTAGT AGCACTTTCA CACCCATACA AGGCCGCATA 
GAAATAGTGC AGAAAACTCA AGCTCATACA AAGAAGGAAG TAGTGGATGC ATTAAATGAT 
GCCATAGACA AGAGAGAAGA GGGGATCATG GTTAAACACC CTCTGTCCAT TTACAAGCCA 
GACAAAAGAG GTGAAGGGTG GCTAAAGATT AAACCAGAGT ACGTCAGTGG ACTAATGGAT 
GAATTAGACG TCCTAATTGT GGGGGGCTAC TGGGGTAAAG GTTCACGAGG TGGCATGATG 
TCTCACTTTT TGTGTGCAGT GGCAGAGACA CCACCTCCTG GTGACAGGCC ATCTGTATTC 
CACACTCTGT GCCGTGTTGG GTCTGGTTAC ACCATGAAAG AACTCTATGA CCTGGGCTTG 
AAATTGGCAA AATACTGGAA GCCTTTTCAT AAGAAATCTC CACCAAGTAG CATTCTGTGT 
GGTACAGAGA AGCCGGAAGT GTACATAGAG CCTCAGAACT CTGTCATTGT TCAGATCAAG 
GCAGCTGAGA TCGTCCCCAG TGACATGTAC AAGACTGGCT CCACCCTGCG CTTCCCACGC 
ATCGAAAAGA TCAGAGATGA CAAAGAGTGG CACGAATGTA TGACACTGGG TGACTTGGAG 
CAGCTGAGGG GGAAAGCATC TGGGAAGCTT GCCACGAAAC ACCTTCATGT AGGTGATGAT 
GATGAACCTA GAGAAAAAAG GCGGAAGCCC ATCTCCAAGA CGAAGAAAGC CATTAGAATC 
ATTGAACACT TAAAAGCACC CAACCTTTCT AACGTAAACA AAGTTTCCAA TGTATTTGAA 
GATGTTGAGT TTTGTGTTAT GAGTGGATTA GATGGTTATC CAAAGGCTGA CCTAGAGAAC 
AGAATTGCAG AATTCGGTGG TTATATAGTA CAGAATCCAG GCCCGGATAC ATACTGTGTT 
ATTGCAGGTT CTGAGAACGT TAGAGTGAAA AACATTATTT CTTCAGATAA AAATGATGTT 
GTCAAGCCCG AGTGGCTTTT AGAGTGTTTT AAGACAAAAA CATGCGTGCC GTGGCAACCT 
CGCTTTATGA TTCACATGTG CCCGTCGACA AAGCAGCATT TTGCCCGTGA GTATGACTGC 
TATGGTGATA GCTATTTTGT TGACACAGAT TTGGATCAAT TGAAAGAAGT GTTTCTAGGA 
ATTAAACCCA GTGAGCAGCA GACTCCTGAA GAAATGGCCC CTGTGATTGC TGACTTAGAA 
TGTCGTTATT CCTGGGACCA CTCTCCTCTC AGTATGTTTC GACATTACAC CATTTATTTG 
GACTTGTATG CTGTTATTAA TGACTTGAGT TCCAGAATTG AAGCCACGAG ATTAGGTATT 
ACAGCCCTTG AGCTGCGGTT TCATGGAGCA AAGGTGGTTT CCTGCTTATC TGAAGGGGTA 
TCTCATGTTA TCATTGGGGA GGATCAGAGA CGAGTTACTG ACTTTAAAAT ATTCAGAAGA 
ATGCTTAAGA AAAAGTTTAA AATCCTGCAA GAAAGTTGGG TGTCCGATTC AGTAGACAAG 
GGCGAACTGC AGGAGGAAAA CCAGTATTTG CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Synthetic lethality between PAXX and XLF in mammalian development.
Genes & development30(19)2152-2157(2016 Oct)
Balmus G,Barros AC,Wijnhoven PW,Lescale C,Hasse HL,Boroviak K,le Sage C,Doe B,Speak AO,Galli A,Jacobsen M,Deriano L,Adams DJ,Blackford AN,Jackson SP

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.
Nature genetics48(5)519-27(2016 05)
Dooley J,Tian L,Schonefeldt S,Delghingaro-Augusto V,Garcia-Perez JE,Pasciuto E,Di Marino D,Carr EJ,Oskolkov N,Lyssenko V,Franckaert D,Lagou V,Overbergh L,Vandenbussche J,Allemeersch J,Chabot-Roy G,Dahlstrom JE,Laybutt DR,Petrovsky N,Socha L,Gevaert K,Jetten AM,Lambrechts D,Linterman MA,Goodnow CC,Nolan CJ,Lesage S,Schlenner SM,Liston A

HELB Is a Feedback Inhibitor of DNA End Resection.
Molecular cell61(3)405-418(2016 Feb)
Tk?? J,Xu G,Adhikary H,Young JTF,Gallo D,Escribano-D?az C,Krietsch J,Orthwein A,Munro M,Sol W,Al-Hakim A,Lin ZY,Jonkers J,Borst P,Brown GW,Gingras AC,Rottenberg S,Masson JY,Durocher D

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Lig4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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