Syne2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Syne2
Entrez Gene ID	319565
Full Name	spectrin repeat containing, nuclear envelope 2
Synonyms	6820443O06Rik,AW546258,Cpfl8,D12Ertd777e,KASH2,NUA,Nesp2g,dice,mKIAA1011
General protein information	Preferred Names spectrin repeat containing, nuclear envelope 2 Names nesprin-2 KASH domain-containing protein 2 diminished cone electroretinogram nesprin 2 nuance nuclear envelope spectrin repeat protein 2 nucleus and actin connecting element protein synaptic nuclear envelope 2 synaptic nuclear envelope protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 12 Map Location: 12 C3\|12 33.11 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001005510.2	NP_001005510.2	nesprin-2

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	SYNE2	XP_003641488.2
Danio rerio (zebrafish)	syne2b	XP_005157085.1
Xenopus tropicalis (tropical clawed frog)	syne2	XP_002933763.2
Bos taurus (cattle)	SYNE2	NP_001193515.1
Homo sapiens (human)	SYNE2	NP_878918.2
Mus musculus (house mouse)	Syne2	NP_001005510.2
Pan troglodytes (chimpanzee)	SYNE2	XP_003314416.1
Rattus norvegicus (Norway rat)	Syne2	XP_006240318.1
	SYNE2	XP_002805134.1
Canis lupus familiaris (dog)	SYNE2	XP_547851.3

Gene Ontology
Bibliography

Related articles in PubMed

p63 Transcription Factor Regulates Nuclear?Shape and Expression of Nuclear?Envelope-Associated Genes in Epidermal Keratinocytes.
Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A
The Journal of investigative dermatology137(10)2157-2167(2017 Oct)

Nesprin 1?2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.
Stroud MJ, Feng W, Zhang J, Veevers J, Fang X, Gerace L, Chen J
The Journal of cell biology216(7)1915-1924(2017 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

nesprin-2G is subject to mechanical tension in adherent fibroblasts
Title: Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension.

SYNE2 is important for normal retinal development. We have determined that not only is photoreceptor nuclear migration affected, but also the positions of Muller glia and secondary neurons are disturbed early in retinal development
Title: A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and M?ller Glia.

nesprin-dependent recruitment of kinesin-1 to the nuclear envelope through the interaction of a conserved LEWD motif with kinesin light chain might be a general mechanism for cell-type-specific nuclear positioning during development.
Title: Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.

Loss of Nesprin 1 or 2, or both, led to impairment of gene expression changes in response to biomechanical stimuli. These data suggest a model whereby biomechanical signals are communicated from proteins of the outer nuclear membrane
Title: Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

ectopic expression of BRAP2 inhibits nuclear localization of HMG20A and NuMA1, and prevents nuclear envelope accumulation of SYNE2
Title: The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins.

The following Syne2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Syne2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20946	NM_001005510.2 Latest version!	Mus musculus spectrin repeat containing, nuclear envelope 2 (Syne2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Syne2 ( NM_001005510.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001005510.2 Mus musculus spectrin repeat containing, nuclear envelope 2 (Syne2), mRNA.

Price & Availability↑

CloneID	OMu20946
Clone ID Related Accession (Same CDS sequence)	NM_001005510.2
Accession Version	NM_001005510.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 20625bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Mus musculus(house mouse)
Product	nesprin-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC159897.2, AC166991.5, AC115714.14 and AC164121.3. On or before Jul 25, 2007 this sequence version replaced XM_001001846.1, XM_917083.3, NM_176945.2, NM_001005510.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849381 [ECO:0000350] ##Evidence-Data-END##

ATGGCCGCTA GCCCTGTGCT GCCCACGGAA GATGGAGAGG GTTTCTTGGG CATTGATGAT 
CTACACTTTT CACTGCAAGC TGAGCAGGAG GACACTCAGA AGAAAACCTT CACCTGCTGG 
ATAAACTCAC AGCTGGCAAA GCACACACCT CCCTCAGTTG TATCTGACTT ATTCGCAGAC 
ATCAAGAAGG GGCATGTCCT CCTGGACCTG TTGGAAGTCC TCTCGGGACA GCAGTTGCCT 
CGGGATAAAG GATCTAATAC ATTCCAGTGC AGAATCAACA TAGAACATGC CCTGACATTC 
CTGAAAAACA GATCTATCAA GCTAATAAAT ATCCATGTTG CTGACATTGT AGAAGGAAAC 
CCGTCCATTA TCCTTGGCCT GATCTGGACC ATCATCCTGC ACTTTCATAT TGAGAAGCTC 
GCTCAGACTC TGTCTTGCGA TTACAATCAA CCTTCACCGG AGGTTGTGAG CGTGGCTGCC 
TCATCTCCTA CCTCAAGTCC TCCCACTAAG AAGTGCTCCA AGGCTCAAGC TCAGGCAAGA 
TGGCAGTGGT CTGCCAAGAA GGCTCTTCTG CAGTGGGCTC AGGAGCAGTG TGCCAGGTCT 
GAGTCTGTCA ATGTGACAGA TTTTAAGTCA AGCTGGAGAA ATGGGATGGC TTTTTTGGCT 
GTCATTCATG CCTTGCGACC AGACCTGATT GACATGGACA GCATGAGGCA CAGATCCAAC 
AAAGACAATC TGAAAGAGGC CTTCAGGATC GCAGAACATG AGCTGAAGAT CCCCAAATTG 
CTGGAACCAG AAGATGTAGA TGTCGTGAAT CCTGATGAGA AGTCCATCAT GACTTACGTG 
GCGCAGTTCC TGAAGTATTC GAAGGATGCG CCTGGCCCCG GGGATTCCAC ACAGGCCAAG 
GTAAGGGATG CTCTGGTCTG GCTAACTCTG CAAGAGAAGA GATTCCAGAA GATGCTGAAG 
GACTCAGCAA GTGAGACCTA CTGTAACAAG TATCATAGTC TGCTGTCATT TATGGAGTCA 
CTGAATGAAG AAAAGGAATC CTTCATTGAT GTCCTGTCAC TGAAAGGGAG GATGGGAGAG 
CTGAATGAAG ATGAATCACG GCTGAGACAA GGCTGGACCA GCCTCATGCA CCAGGTCGCT 
GCGTGGAGAG CCCAACTGGA TGACGCCTTG CCTTCACCGC TCAAAGAGAC CGAAGCGTGG 
CTGAAGGACA TAGAGGGTGT TGTGCAAGAA GGGGTGCCGA CCTCCCAGAG TTACTCTGAA 
GCCAGGACTC TGATCCAAGG GAAACTATCT TCATTCAAGA GTCTGATGGG CAGCTTTGAC 
TATCATTCGG ATGTTCTCAT GGCCTTTCAA TCCAATGCCG AGAAGAGCCT GCCAGCTGTG 
CCTCCTGTTA AACTGGAGGA GATGACAAGA CGAATCAACA ACGTTTTGGG TAAAAACTTC 
ATCCCACTCC TGGAGTTTCA TGACTCTAAG TGCTCAGTTC TGGCTTTGCT TGATGAAGCG 
AAGGCCAAGT TGGATGTCTG GAACGGCACT TATGAGAGCA AGGAGTCTGT GGAAGTCCTG 
CTGGAAGACT GGCATAAATT TACTGGAGAA AAAAAGTTCC TAATTCAACT TGATGCTTCT 
TTTCAAAAAT GTGAAGAAAT GTATAAGAAC TCGGCCAGAG AATGTGAGAG TATTAGAGAG 
GAGTATATGA TGCTGGAAAA GAATGTTCAC TCGTGCAGAC AATACATCCA TAACACGAAG 
GCCACACTGC AAAGAGCACT GATGTCTTGG GCAACTTTCG AGGAAGATCT CGCCCTACTA 
AAGGCTTCTT TTGACTTGAC AAAGAAGGAA CAAATTAAAG AGGTTCCCGT TGAGACCCTC 
TTGCAGTGGA ACACAAAACA CACATCTTTG AATGAGGTGG GGAGTTTCCT GATTGGAGTC 
AGCAGTAGAG AAGTTGCCGC ATCTATTTCT AAAGAACTGA GAAGGCTCAA TAAAAGATGG 
AGAAAGTTCA TCACCAAAAC TCCACTTCTG AAACTGCCAC TCGTGAAAAT TCAGGACCAG 
CCCCCTGGGA ACAGTTCTGG AACGAGTCTG TCTAAGGAGT CAGCTATGGC AGCAGAGCCT 
GGTGGAAGCC GTGGTGAGGA TGTAAAGGCT GCGGAAAAGC AGGAAGTAGA AGACGAAGAG 
TCAGCCGGAC AATTGAAAGT GAACGAAGAA GTTGAAGGAC TCATCAAGCA GGTGACAATC 
TGGGAGTCAC AAACCAAATC CATCTTGGAT CTCCTCCAAC ATGGAGACCA TGCCGATGGC 
TCCTCAGCAG ACACCTTGCA GCATCTTATT GCTAAAGGCT CTGTGTATGA GGAACTTCTG 
GCCAGAACCG AAGATACTTT ACAGATGGAT GTTCAAAGTC CTTCGAACCT GGAGCCCTTC 
CAAAATGTCC TCAGAGCTGG CCTTCAGGCA AAGATCCAAG AAGCTAAACA AGGAGTTCAG 
ATCACCATGG TAGAATTGTC TGCAGTGTTG AAGAACTTAA GTGATGAACC ACTGGAGCTA 
GACCTGGGGC TAAAGGTGGA GGAAGCGCAG AAGGAGCTGG AGGTCTCCAT CTTGAGAGCC 
GAGCAGTTAC TCGGGCAAAG AGAGCGCCCT GGTGGATTCC TCTTGAAGTA CAAGGAAGCA 
TTGGAAATTC TTAATACCAA TAGTCTGGCC AAGTATCTTC GAGCTGTTGA AGAACTGAAG 
CGTACTGTCC CCGGTGGTGC GAAGCTGCAG CTGGAAGAAC AGAGTCGAGT CGCAAGTGCC 
AAGTGGGAGC CGCTCCGTCA TGAAATTTCT TTGTATCTCC AACAACTAAA AATAGCTATT 
GAAGAAGAAA AGCTTAGAGA CAATATTGCG AGACTTGAAA AGCAAATAAA TAAAGAAAAG 
AAGCTTATCC GGAGAGGCAG GACCAGGGGC CTCCGCAAGG AGCACGAGGC TTGCTTGTCT 
CCGGAAAGCA TCAAGTGCCA GCTAGAACAC CATGTGGGTG TCTTGAGGGT GCTGTGCGAG 
GAGCTGACAT CACCAGAGGA TCAACAAGAA TTGAAGAGAG CACTCCGAGA TTACGAACAA 
AAGATAGCGA GACTTCTGAA ATGTGCTTCT GAGATTCACA CAACCCTGCA GTCCTCCCAG 
GGAGGTGCAT TGGAGGAGAG GAGTGCCTTG ATCACAACTG AGAATGGCAG AAGGGATGCC 
GATGGCGAGG TACCACTTGA GATACCAGAC AACCAGCTGT CAACTGAAAA GGCGATGGAA 
CCCATTAAGA ATTTTAGCCA GACATCAGAA TTAAAGCCTC AGCAAGAAGA AAGCATTATG 
GAGAAGGAAG GAAAGGATTG CAGCGCCTCT CTAAGTGACT TACAGGAGAG GTATGACACA 
CAAAGGGGGC TTCTTGAGCA ACACCTGCAA GACAGCAAAT CCAGGGTGAC GTCTGACTTT 
GCCAGTGAGC AGGAGAGGAG CAGCGCCTGC CTGCAGAGTA AACTGGCAGA ACTGCAGGTC 
TTACTGGCTG ACACTGATGC TCACTGGGAG AAGTTTGAAA TCACTTCACT GAATTTAAGA 
AGACTGATGA GCGACGCGGA GAAGCCTGTG CTTAACCAGG AGAGAGACTT ATTAAAGGGG 
AATGAACAGG TTCTTCACGG GCTTCTTAAC ACCAGAATGG AGTCACTGGA GATGGCGCTG 
CAGATAGTAC TTCCTCTGGA GAAGGAGTGT TCTCTCCTGT GTGCCTCTGA CCTGCCCCTC 
TGCACAGTGG CTGTCCAGGA CCTGCATCCT GTTGAGATTG ATGGTGTCTA TCAGAACCTG 
CGGGATATCC GAGATTCCAT CGCAAAGCAG ATCAGAGTCT GTACCAGTTT GGAGGAGCCG 
AGTAACTCTG TACCAAGGGA GTTACACACA CTAGATCAGT GTGCGATCCA GGACATTGTG 
CTGAAGTGCA GACTCCAGCT GGAGACCATG AACCAGAAGG TAGAGATGAG GGAGGATGCC 
CTGGATGCTC TGGAAGGGTT TTTGGCATCT CTGAGAGCAG CTAAGCTCTC TGCTGAGCTC 
CCTGCAGACC GTCCTGCCCC GAAAGCACCA GAAGTGCTGA GTGAAGACAT TCTCCTGATG 
AAAGAGAAGG CCGGGCCTTT GGATGAACGC CTGAGGACAC TTGGCATAAA CATTAAGGAT 
GCCGAGGGAG GGGAGAATAC CACCTGTGAA AGACTGGTCG GTGCATTGTC AGTAAACTTA 
GTGGCCATGG ATGGCCAGAG TAAAGAGGAA GGACCTCCTG AGGACAAGAA GTTACTGGAA 
GCTTGTAGTT CCAAAAATCT CGAGCTCTTT AAAAACATTC AAGACCTCCA GAATCAGATC 
AGTAAAATTG GTCTTAAGGA TCCTACTGCT CCAGCCGTGA AGCATCGGAA AAAGTCATTA 
CTCAGGCTGG ATAAGGACCT AGATGGATTG GAAGAAGAAA AGGTGCGCAT ACAAAAAATA 
GCTGGCTCTC TCCCACGATT CAAGGATGGC AGTGAGAAAA ACGTGATTCA ACAGTGTGAA 
GACACAGCAG CCTTGTGGGA GAGTACGAAA GCTTCTGTCA CAGAGAGCCT TGAACAGTGT 
GGAAGTGCTC TGGAGCTCTT ACGACAATAT CAGAATATTA AAAACAACTT GACAGCTTTG 
ATTCAGAAGG AAGAGGGCAT CATCTCCCAG CAAGCTTCCT ACATGGGAAA GGACAACCTG 
AAGAAGAAGA TAGCCGAGAT TGAAACTGTC AAAGAAGAAT TCAGCGACCA TTTAGAAGTT 
GTAGACAAGA TAAATCAGAT TTGTAAAAAC CTACAATATC ATCTGAATAA AATGAAAACC 
TTTGAAGACC CCCCCTTTGA AAAAGAGGCT AATGCTATTG TGGACAGATG GCTTGATATT 
AATGAGAAGA CAGAAGAATA TGGTGAAAAT CTTGGCCGAG CGCTGGCCTT GTGGGACAAA 
CTTTTCATCA TAAAAAACAA CATCGATGAG TGGACTGAAC AGATCCTTGG GAAAGCAGAA 
TCCCATGAGC TGACTGAGGA GGACAGAGGA AGGCTGAAGG AAGAGTTAAA AGTACTCGAA 
GAGCAAAGTG CAGAATTTTC TAGAAGAGTG GCTGACATAC AGTCGTTGCT TCAGAGCAAT 
GAGAAACCAC TTGAACTGCA GGTCATGGAG TCCTCTGTCC TGAGCAAGAT GAAAGATGTG 
AAAACACATG TCGCAGGGGG ATCCAACAGC TATGCGCCCA GTGGGAGCAC AGCTGAGCTG 
AGAGAGGATC TGGACCAGGC CAAGACCCAG ATGGGGATGA CTGAGTCCCT CCTGAATGCC 
TTGTCTCCCT CTGATAGCCT GGAGATCTTC ACAAAGCTTG AGGAAATCCA ACAGCAGATC 
TTTCAGCAGA AGCACAGTAT GACGGTCCTG GAAAATCAAA TAGGGTGCCT CACTCCAGAG 
CTCTCCGAAC TGAAAAGACA GTACGCAAGT GTCAGCAATC TATTTAATAC CAAAAAGAAC 
GCGCTGCAGG ACCACTTTGC CACGTTCCTG AACGAGCAGT GTAAGAACTT TAACGACTGG 
TTCAGCAACG TCAAAACGAA TCTTCAGGAG TGTTTTGAAC CACCAGAAAC AAAACTGAGC 
CTGGAACAAA GGCTGCAAAA ACTTTCTGAT TTCTTGACTC TTGGAGGAGG AAACAGTAAA 
ATACAGCAGG TAGAGACCGT CCTACAGCAT GTGAAGATGC TCTTACCCAA AGCACACGTG 
AAGGAGCTTG ACAGCTGGCT CAGGAGTCAA GAACTGGAAT TAGAAAATAT GGAGTCCATA 
TGCCAGGCCC GAGCAGGGGA ACTGAATAAC TCCTTTCAGC AGCTACTGAG ATTGGAAGAT 
GATTGCAGAA GCCTAAGTAA GTGGCTGACT AATCAAGAAG AGAACTGGGG AAAAATGGAA 
GTATCAGGAG AGCGAATGGA TCTGTTTTCC CAAGCATTGA CTAGGAAGAG GGAGCAGTTT 
GAGACTGTGG CCCAGCTAAG TGACTCTCTG AAGGAGCATG GGCTCACCGA GGGAGAAGAG 
ACAATCAAAG AATCCACACA TCTGATCGAT AGATACCAGG CTTTATGGAG ACAATTACAC 
GAAATTGAGG AAGAGGATAA GTTACCAGCG GCCGAAGACC AGAGCTTTAA CGATCTTGCT 
GATGATGTAA TTCACTGGAT AAAAGAGATT AAAGAGTCCC TTATGGCTTT GAATTCATCA 
GAAGGCAAAA TGCCACTCGA AGAAAGAATC CAAAAAATAA AGGAAATCAT TGCCTTGAAG 
CCAGAAGGAG ATGCTAAGAT CCAGATGGTA ATGAGACAAG CGGAACACTG TGAGGCCCCG 
CTGGCTCAAG AGACCTTTAC GGACCTCAGC AACCAGTGGG ACAGCACGCT CCACCTCGCC 
AACACATACC TCAGCCATCA AGAAAAGCTT GTACTAGAAG GAGAAAAGTA TTTGCAGAGT 
AAGGAGGACC TGAGGCTGAT GCTCACAGAG CTGAAGAAGC AGCAAGAAGC AGGCTTTGCT 
CTACAGCCTG GGTTGCCAGA GAAGCAGGCC CAGTTAAAAA TTTATAAGAA ATTCCTCCAG 
AAAGCCCAAG ATTTGACATC CTTGCTAGAG GAGCTAAAAT CTCAGGGCAA TTACCTCTTG 
GAGTGCACTA AAAATCCCAG CTTCAGCGAG GAGCCGTGGC TAGAAGTGAA GCACCTGCAT 
GAGAGCCTTC TCCAGCAGCT CCAGGATTCT GTGCAAAAAT TAGAGGGTCA TGTTCAAGAA 
CACAGTTCCT ACCAGGTTTG CCTCACAGAC CTAAGCTCCA CACTGGATGA TATCTCCAAG 
GAATATTTCA GTCTTTGTGA TGGATCTAAG GACCAAATAA TGGCTAAGGA GAGAATGCAG 
AAGTTACAGG AGCTGGAGAG CAGACTCCGT TTCCAAGGCG GTGCGTTAAA GAAGGCTTCT 
GCTTTAGCGA AATCCATCAA GCAAAATACA TCTTCAGTGG GACAGAAGAT TATTAAAGAT 
GACATAAGAT CGCTTAAGTA TAAACAAAAG GATTTGGAAA ACAGAATCGA ATCTGCCAAG 
CAGGAGACTG AAAACGGTCT CAACAGCATC CTTAAATCCA AAAGCTCAAC AGAAAAACAT 
GTAAAGTTTT CTCTGCCAGT TGAAGAGATG CCGGCCACTT CTGAGGTGCC CAAGCCCACT 
CGGGAGTCGG CAGCCGTGGG CGAGTCAGGA GGAGCCCGGG AAACAAACAC GAACTCAGCT 
GTGGAAATGA TTTTGTCAAA ACAACTTTCT CTCAATGTTC AAGAAAGCAT GCAAAACGCC 
CAAGATGAGC GGGAAGTCAA CGAGCTGCAG AATCAACCTT TAGAATTGGA CATTATGTTA 
AGAAATGAAC AATTAAAAGG GATGGAGGAA TTATCTACTC ACTTAGAAGC AAGAAGAGCA 
GCCATTGAAC TTCTGGAACA GTCGCAGCAT CTCAACCAAA CAGAAGAGCA AGCCTTGGTT 
CTGCCCGCCG CCAGACCTTC AGTGTGCCAC TTGGGCAGTC TACAGCAGGA GCTTCATACC 
TTGAAGAAAA CTAAAGAAAG ACAGTATGGC CTCCTTAGTG GTTTTCAAGA CCAGCTGGTG 
ATGGCTGAAG CCTCCCTGAA CACCTCCTTG GCAGAAGTGG AAAGCCTCAA AATAGGCTCG 
CTAGACAGTG CAACCTATCT GGGGAAAATC AAGAAGTTCC TGGGGTCCGT GGAAAACCAG 
CAAGGCTCAC TGAGCAAGCT TCGCACCGAG TGGGCACATT TATCCAGCCT CCTGGCGGCC 
GCAGACCAGA AGCTGGTGGA GAGCCAAATG AAGCACCTTG AACATGGGTG GGAACTTGTG 
GAGCAGCTGG CTCACAGGAA GTGTTTCCAG CAAGCCACAG AACACAGCGA ACTCACCTGC 
CTCCTGGAGA AGCTCCAGGA CCTTAAGGTT TCTCTGCATC AGCAGCAACA GCGCCTAACG 
CTAAGTCTGA ACTCTCCAGG ACAACAGGCG GCGATCGTGG ACATGGTCAC TCCAGCCGCT 
GAGCTCCAGG CAATCAAGTG TGAGTTTTCT GGCTTAAAGT GGCAAGCTGA GCTTCACATG 
AAGAGGCTTT GGGGAGAAAA GGATAAGAAA ACTCTGGAAG ATGCAATAAA TAATTTGAAT 
AAGCAAATGG AAGCACTGGA GCCGTTAAAC CGAGAGGTAG AAAATCGGAT TAAAAAGTGT 
GAGCTCCAGA ACAGGATAAA GGAGACTCTG TCCTGGGTCA AGAACACGAT GGCGGAGCTC 
GTTGTTCCCA TCGCCCTTCT CCCTGACAAC ATCCTTTCTC AGATCAGAAA GTGCAAGCTG 
ATTCACGATG GCATTCTGGG TAACCAGCAG GCAGTGGAGT TGCTGGTGGA AGAGGTCAGA 
GGCATCACCC CCAGCCTTGC ACCATGTGAG GGTGACGGTT TAAATGCTCT CCTGGAGGAT 
TTACAGAGCC AACACCAAGC ACTGCTTTTA AAATCAACTG AGAGGTCCCA GCAACTAGAA 
CTGAAGTTGG AAGAAAAAAG CAAACTGTTT GCGATTATAG GTAAGGTTCA GCTCACGCTT 
GAAGAAAGCG AAACACTGAT GTCGCCCACG GGGGACAGAG CCTCCACGGA AGCCGAGCTG 
GAACGTCGCC TCGCCATCCT GAAGGCATCC CAGCAGCAGC TGCAAGACAC GGAGAGCGCA 
CTCTCGGCCC ATCTTCAAGA ACTTACAAAT GCCTACAAGG ACGCAAACGT GTTTGAGAGA 
TTATTTCTGG ATGATCAGTT AAAAAATCTC AAAGCAAGGA CCAACAGAAC ACAGAGATTC 
CTTCAAAACA ACGGTAGCGA ACTCAAGCAG AAGATGGAGT CTTACAGAGA ATTCCATGAC 
AAAGCAGCAG TGCTTCAGAA AGAGGCTGAG TGCATCCTGC ATGGTGGACT TCTCCCGCTC 
CGTCAAGAGC TGGAGCAGGA TGCCAAAGAG CAGCTCGGCA ATCTTAGAGA CAAGCTGGCT 
GCTATTCGAG GCAGTCTCTC ACAAGTGTTG ACATCTGAAG AAGTGTTTGA CACTATAGGG 
CTAAGCTGGG ATGGTTCACT GCTAGCACGG TTACAAACCC AAGTGCTTGA AAGGGAGAGA 
GAAGTGGAAG GAAAAATTAA GCAGCTGGAC ACATTTTTAA TAGCACGGGA CAGACACCAG 
GCATCGATAA GTAAGATAAG GGCTGTGGAT CTGCAGATTA AGAAAGGGGC TGAATCACTA 
CTGAAAGTCC CCAGTATGTC ACCAGAAAGC ACTCTGCTCA ATGCACAAAC TTTGATTCAG 
AAAATTGAAA AATCCAAACG CTTGCGTGAT GAGATAATCA GGAAATTAAG CAAAAACGAG 
GCTTTTGACG ACTCGTTCAA AGAGAGCGAG ATGCAGCGAC TAAAGCTATG TGCAGAAGAG 
AATTCTAGGC TTCAAGAGGC TCTCCAGAAC ATGCTGCTAG AATTGCAACC AAGAGAAATG 
GGCGAAAAGG AATTCCGAGA GAAGCTAGAA AACGCCCTAC ATGTTTTAAA GCAAATACAG 
TCTCGGTTAC AGCAGCCTTT ATGTGTAAAT TTGGGGGTTC AACATATTCA ACACGAGAAG 
GAGACCTGGG AAGCATTTGG CGAGCAAGTC GAGGCAGAAA TGTGTGGTCT TAGAGCCGTG 
AGGATTACCG AAGAGCAAAG AGAAGAAAAC GATTCTGGAA CCGGTGGCAT GGAGGCAAAA 
TTACGGGACA TTGAAGGTCT TCACATGGAG CTTAGCAAAA GCATTAGTCT ACGTGCAGAT 
GTCCTGAACG ATGCTTATGA CAGTGCAAAC CGCTATGACG AGTTAGTAGC TGGGGCATTG 
AGAATCATCA CGTCCCTGGA AGCCACGCTT TTGTCGTACA GAGTAGACCT TCACAATCCC 
CAAAAGACAC TGGAGCTGGC ACACCTTAAA CAAGAGGAAC TGCAATCCTC CGTAGCTGAT 
TTACGGAGCC TCACCGAGAC TTTGGGGGCT ATCTCCAGCC CTGAGGCCAA AGAGCAACTT 
CGTTGTACTT TAGAAGTTCT AGCAGCTAAG AATTCAGCCT TGAAGGCAGG GCTGGAAGCC 
CAGGAGGCCG AGGAGGAAAG GTGCCTGGAG AATTACAAAT GCTTTAGAAA AATGAAAGAA 
GAAATTTGCT CTCGGCTCAG GAAAATGGAG ATGGATCTCG GACAGTCCAT ATTCCCGTTG 
CCCAGGTCTT ACAAAGAAGC CTTAGCGCGC CTGGAACAGA GCAAGGCGCT AACATCAAAT 
CTCCTGTCAA CCAAAGAAGA CTTAGTGAAA CTCCGTCAGC TCCTCAGACA CCTGAGATGC 
AGGAGCACAG AAAACGATGC CACATGCGCG CTTGGGGTGG CCTCCGCTCT GTGGGAGAAG 
TGGCTGAGTT TGCTGGAAGC CGCCAGAGAG TGGCAGCAGT GGGGTGGAGA GCTGAAGAGA 
GAGTGGAAGT TCATCAGTGA GGAGATTGAG CGAGAAGCAA TAATTTTAGA GACTCTTCAG 
GAGGACCTTC CAGAAATTTC CAAAACAAAC GCAGCTCCCA CCGAGGAACT CTGGCAGTTG 
TTGGACTCTC TGTGCCAGCA CCAGGAGAGT GTGGAGAAGC AGCAGCTGCT GCTGGCCCTG 
CTTCTACAGC GTGTCAGGAG TATCCAGAAC ATTCCCGAAG GCACCGAGAC CGGGGAAACC 
ATCCCGGCAC TTCAGGAGAT TGGGTCTATG CAAGAACGGT GCGACAGGCT TCTTCACACA 
ACTCGAAAGA ATAAGGACCT GGTCCAGGCC GAAATCCAGG CACAGCAGTC TTTCCTAAAG 
GAAATAAAGG ATGTGAAGCG TGTATTTGAA CAAATCTCAA CTTCTTTCCC AAACTTGGCA 
CCGGAAGGCC ACCCAGAACG GGCAGAACAG TTTGAGGAGC TGCGGAGCAT TCTTCAGAAA 
GGCAAGCTGA GTTTCGAGAA CATTATGGAA AAACTGCGCA TCAAGTATTC CGAGATGTAC 
AGCATAGTCC CTGCGGAGAT CGGATCCCAG GTGGAAGAAT GCAGGAGTGC CCTAGAGGAT 
GCTGAGGAGA AGATGAGCAG TGAAGTCTCA AAGAGCTCAC CATCAAGCAT CATGAGGAGG 
AAAATAGAGA GGATTAACAA CGGGCTCCAT TGTGTTGAAA AAATGCTGCA ACAGAAAAGC 
AGAAACATTG AGGAAGCTCA CGAAATCCAA AAGAAAATAT GGGATGAGCT CGACCTCTGG 
CATTCCAAGC TGAACGAGCT GGACTCTGAA GTTCAGGACT TCGTCGAGCA GGACCCAGGA 
CAGGCGCAAG AATGGATGGA CAACTTGATG GCTCCTTTCC AGCAACATCA ACAAGTATCC 
CAGAGAGCAG AATCCAGAAC CTCGCAGCTC AACAAGGCCA CGATCAAGAT GGAAGAATAC 
AATGATCTTC TGAAGAGTAC AGAGGTGTGG ATAGAAAAGA CCAGTTGTTT GCTGGCCAAC 
CCTGCCTGCT ATGACTCTTC AAGGACCCTT AGCCACCGCG CCAGCACCCT CCAGATGGCT 
CTGGAAGATT CTGAGCAGAA ACACAGCCTT CTACATTCAA TTTTCACGGA TCTAGAAGAC 
CTGTCAATCA TTTTTGAAAC AGATGACTTA ATCCAGACCA TTCACGAGTT AAGTGACCAG 
GTGGCCGCTT TACAGCAACA GATAATGGAG GCCCTCCCAC ACGTCCAGCA GGTGGCAGAT 
GATGTGGTTG CGATCGAGTC TGAAGTAAAA GCAATGGAGA AAAAGGTTGC AAAGATCAAA 
GCTATCCTCT TATCCAAAGA AATATTTGAT TTTCCACCTG AAGAACATCT CAAGCATGGG 
GAGGTCATAC TTGAAAACAT CCATCCCATG AAAAAGACTA TTGCTGAGAT AATGACTTAC 
CAAGTGGAAC TGAGGCTGCC CCAGACGGGA ACCAAGCCCC TGCCTGTGTT TCAGAGGACA 
AGCCAGCTTT TACAAGATGT GAAACTCTTG GAAAATGTGA CTCAGGAACA AAATGAGTTA 
CTGAAGGTTG TCATAAAGCA GACTGCTGAA TGTGATGAAG AAATAGACAG TCTGAAGCAG 
ATGTTAACTA ACTACTCAGC TGAGATCTCC CCTGAACATG TGTCACAGAA CCAAGTGGCC 
GACCTGCCGT CGTTACAGGG AGAGATGGAA AGGTTGGAAA AGCAGATTCT GAATCTAAAC 
CAGAAGAAGG AGGATCTGCT AGTGGACTTG AAGACTGCTG TACTGAACCT TCATGAGCAC 
CTGAAACAAG AACAGCAAGA AGTAGGAGAC AAGCCCTCTG CAGGCGCCTC CGAGTGTACA 
GTGGCCGAGA GGGATGCTTC AGAAAGGAAG CTGAGCAGAA CAAACTCCAT GTCTTTCCTG 
CCAGTGGTCA AGGAGGAGGC CGAAGAAAGC TCCGTGAAGA GCGAAGATGG ACGTAGGAGA 
ACAGAGCCAC CGTCCGCATC CTGGTCTTTT CTGGGGAAAC ACAGCAAGGA CCTGGAAGGG 
GATGGGGCAT CCTCCTCCTC CTCAGCCACC ATCGTGCAGG ATGCAGATGG GAGAATTAGC 
ACCTGTGACA GCTCCATGGT GCATATCATT GCCCCAGACT CGGGAAGCAC CGAGGAAGGA 
CCAGCACCAT CCCCGAGGCT CAGCCAAACA GACGAGGGTG CCACACCCCC CATTGAAGCT 
GCACTCCTGG ACTTTCCTAG AGAACAAGGA GCTTTTGAGT CCACCGTGGA GAGAAGTAGG 
CCTCGGCCTG CAGACATCCT CCGTGTCTGC AAGACCCAAG TGGCCAAGCT GGAGCTGTGG 
CTGCAACAAG CCAACGTGGC CTTTGAGCCA GAAACTGTAG ACGCGGACAT GCAACAGGTG 
GTGGAAGAGG AGCTGGCGGG GTGCCAGGCT ATGCTGACAG AGATTGAGTA CAAGGTCGCC 
TCTCTGCTAG AGACGTGCAA AGACCAGGGC CTGGGAGACT GTGGGACCAC TCAGCAGGAG 
GCCGAGGCCC TTTCCTGGAA ACTCAAGACT GTGAAGTGCA ACTTGGAAAA GGTCCAGATG 
GTGCTTCAGG AGAAGTTCAG TGAGGACCAG CATCCCTCCA CTCTTAAGAA ACCGTCAGAG 
CCCCACGACG TCGACCAGCC AGCTGGCCTT TCTGAGCTTG ACTCTGTCCT AACTGAAAGG 
CCACAGTTCA GCAGACAGAA GGATGCTCCC CAGCCACAGA TTCTGGAGTT AAAACCATCA 
GAGCAGAAAG ATTTAATCAA GTTCACAGAA CTGAATGCCA AGAAAACATG GCTGCAGGGT 
CACCAAGAGA ATGAAGATGC AAATCGGCAA TCAGCTTCCA GCAGCAAGGT CCCTAGTCCT 
GGGAATGCAG CATCAGATTC AACCTTGCCA CTTCAGGCCC AGAGCGGTGA CAAGTGGCAG 
TATCTTCACC ATGAACTAAC ATCAAGACCA AATCCCTCCG TACCTCAGCT TGTGGAGCCT 
CAGGTGGCCC TAACTACAAG TACTCTGCCC AGTGTGAGCG TGTATAACTT TAGATGCCCT 
ACAGCTGACG AACTGCAAGC TTACACCACC CAACTTGAAG AGCTACGCCA AGAAGCAAAC 
ACTATTCAGA CACAGGGAAG TATGACGGAA GAGACGTATA TCAGTTTGGA TAAAAGATTA 
TTTGAACTCT TTCTGAGCCT CAGTCGGTGC CTGGGCAGTG TGGAGGGGCT GCTGCAGAGA 
CCTGGGTTAC TCAGAGAGGA TGCATGTGCC CAGCAGGTGT TCTTCCAGAA ACTGGCTCTT 
GAGCTGAAGA AACTTTATTT AGCTCTGGGT GACAAGAAGG ATGATTTTCT GAAAGCTGTG 
ACTTGGCCTG GCAAGGAAGC CACGTTGCTA CCAGAATGTA TTGATGCTCT GACAGTCAGC 
CTGGAGAGTG TGCAGAGCAG AGCTGCCTGG AGGGACGCAT CCCTGAAGGC CGGCCTTGAG 
CACAGCCGCA GCTACCAGAA TGAAGTAAAG CGATTATACA GCCAACTCAT CAAGAAGAAG 
ACGGCTTTGC AACAGTCTTT GAACGAAATC AGTGGGCAGA GTATTAGCAA ACAGCTTCAG 
AAAGCAGATG TGCATACAGC AGAGCTGCAG AACTCTGAGA AGCAAGTCGC CAAACTGAGA 
GACGAAGGGG AGAGGCTCCG TTTCCCTCAT GGTTTACTCC AGGACGTCTA CAAGTTGGAG 
GATGTTCTTG ACAGTATGTG GGGAATCCTG AGAGCCAGAT ACTTAGAACT CAGCAGCCCC 
TTCCTCTCCA AGAGCCTGCA GACCTTGCTT CAAGGCATGG CGGAGCTAGT CAGTATTGGA 
AAAGGAAAGC TGGCCGCTGA CCCTTTGCAA CACGCCAAGA GCAAAGCTGC TTTGCAGGCC 
CAGTTACAAG ATCACAAGGC GTTTTTCCAG AAGCTTGTGG CCGACATGTT GTTGATTCAA 
ACCTATTCGG CAACAATGTT TCCACCTTCG TTACAAAAGG GAGAGGGATT TGGAGCAGAG 
CAAGTTGCGG AAGTGAGAGC CCTGGAGGAA GAGGCCTGCC TGCGTGGTGC GCAGCTTCAG 
AGCATGCTAC AGAAATGGGA AGAATTTGAT GATAACTATG CATCCCTTGA GAAGGACCTG 
GAAGCTCTCA TCTCTTCGCT GCCCTCCGTG AGTTTGGTGG AAGAGACGGA GGAGAGATTG 
CTGGAAAGGA TTTCATTTTA CCAGCAAATA AAAAGAAACA TTGATGGGAA GCATGCCCGG 
CTTTGCCAAA CCTTGAATGA AGGCAGACAG CTGGCAGCAT CTGTGAGCTG TCCTGAGCCA 
GAGGGCCAGA TCGCGAGGCT GGAAGAGCAA TGGCTGTCCC TCAACAAGAG AATCGACCAG 
GAGCTCCACC GACTGCAAAC CCTTCTTAAG CACCTTCTCA GTTACAGCAG AGATTCAGAT 
GAGCTAACCC GGTGGCTGGA GACTTCTCAG CAAACGTTGA ATTACTGGAA AGAACAATCC 
CTCAACGTGT CCCAGGACCT GAATACAATC AGAAGCAACA TAGACAGATT TTTTAAATTT 
TCCAAGGAAG TCGATGAGAG GTCCTCCCTG AAGTCCGCAG TCATGAGTAC TGGGAACCAA 
CTTCTCCACC TGAAAGAGGC AGACACGGCC ACACTGAGAG CCTCTTTAGC ACAATTTGAA 
CAGAAGTGGA CAGTGCTCAT AACTCAGCTT CCAGACATAC AAGAGAAACT TCACCAGCTT 
CAGATGGAGA AATTGCCGTC CCGAGAAGCA ATCTCCGAGA TGATCAGCTG GATGAACGCC 
GTGGAGCCTC AGGCGGCGGG CAAGGATACC GAGCTCTCAA AGAGTTCTGC GTCTCAGGTG 
AAACATCTTC TGCAGAAGCT CAAGGAGTTC AGGATGGAAA TGGACTACAA GCAATGGGTA 
GTTGACTTTG TTAACCAGTC GCTGCTCCAG CTAAGCACCT GTGACGTAGA AAGCAAGCGC 
TATGAAAGGA CGGAGTTTGC TGAGCACCTC GGGGAGATGA ACCGCCAGTG GCAGCGAGTG 
CACGGAACCC TGAATAGAAA GATACAACAT TTGGAACAAC TTTTGGAAAG TATCACTGAG 
AATGAAAACA AAGTACAGAA TTTGAACAGC TGGTTGGAGG CACAGGAAGA AAGGCTGAAG 
ATGCTACAAA AACCCGAAAG TGCCGTCTCC ATGGAGAAGC TGTTACTGGA CTGCCAGGAT 
ATAGAAAACC AGCTTGCCCT GAAATCTAAA GCTCTGGACG AGTTGAGACA AAGTTCTCTG 
ACAATGGATG GGGGAGACGT GCCATTGTTA GAAGACATGG CATCTGGAAT TGTTGAGCTG 
TTTCAAAAGA AGAATAACGT GACCAGCCAG GTCCACCAGC TCAGAGCTTC TGTGCAATCA 
GTACTACAGG AGTGGAAGGC CTGTGACAAG CTCTATGATG AGGCCACCAT GAGGACAACC 
CAACTCACAT ATTCCATGGA GCACAGCAAG CCTGCGGTCT TATCGTTGCA GGCCTTGGCC 
TGCCAGGTGC AGAACCTTGA GGCCCTTCAG GATGAAGCTG AGAACGGGGA ACGGAGCTGG 
GAGAAACTGC AGGAGGTCAT TGGCAGACTC AAAGCTTCCT GCCCCTCCAT GGCTGGCATA 
ATCGAAGAGA AATGCCAGGA TGCTCATTCG AGGTGGACCC AAGTGAACCA AGACCTCGCA 
GACCAGTTGC AGGAGGCCCG AGGGCAGCTG CAGCTCTGGA AGGCTCCTCA CAATGCTCAC 
GCAGAAGCGG CAGCCTGGCT GCAGCAGCAG GAAGCAAAGT TCCAACAGCT TGCCAACACC 
AATCTGTCTG GAGACAACCT GGCAGATATC CTGCCACGGG CCCTGAAGGA CATAAAGGGG 
CTGCAGAGTG ACCTGCAGAA GACCAAAGAG GCCTTCCTGG AAAATTCTAC CCTCTCGGAT 
CAGCTGCCAC AGCCTGAGGA GCGCAGCACC CCTGGGCTCC ATTCTGGACA GCGGCACTCC 
CTCCAGACAG CTGCCTATTT AGAAAAGATG CTGCTGGCAA AATCAAATGA ATTTGAGATT 
GTTCTGGCAC AGTTTAAGGA TTTTACAGAC CGGCTGGCAT ATTCAAAAGA CCTTATTGTG 
CACAAGGAAG AAAATCTGAA TAAACTTTAC CATGAAGAGA AAGAAGAAGT TCCTGACTTG 
TTCCTGAACC ACGTGCTGGC CCTGACAGCC CAGTCACCTG ACATTGAACG TTTGAATGAA 
GAGAGCCTCA GGCTTCCCCT CAGTGACGTA ACAATAAAAA CATTACAAAG CTTGAACCGG 
CAGTGGATCC GGGCTACGGC CACAGCGCTG GACCACTACA GCGAACTTCA GGGAAATGGG 
TTGAATGAAA AGTTCCTTCA TTACTGTGAA AGATGGATCC AAGTTCTGGA GAAGATCCAA 
GAATCACTTT CAGTGGAGGT TGCCCACAGC CTCCCTGCTC TACTGGAGCA ACAGAAAACC 
TACGAGATAT TAGAAGCTGA AGTCTCTACA AACCAGGCAG TCGCTGACGC TTATGTGACC 
CAGTCCTTAC AACTCCTGGA CACAGCAGAA ATAGAAAAGA GACCAGAATT TGTCTCTGAA 
TTCTCCAAGC TGTCAGACCA ATGGCAGAGG GCCGCCCGGG GTGTTCGGCA GAGGAAGTGT 
GACATCAGCA GGCTGGTGAC ACAGTGGCGG TTCTTTACCA CCTCTGTGGA GGACTTGCTG 
CGGTTCCTCG CCGACACCAG CCAACTACTG TCTGCAGTGA AGGAGCAGGA CTGTTACAGC 
CTCTGCCAAA CCAGGCGCCT GGTCCACGAG CTGAAGAGCA AAGAGATCCA TCTTCAGAGG 
TGGCGAACAA CGTACGCACT GGCCTTGGAA GCCGGGGAGA AGTTGCGGAA CACACCCAGC 
CCAGAAACGA GAGAATTCGT AGACGGACAA ATCAGCAGGC TTCAGGAAAG CTGGAAGGAC 
ACTGAGCTTA GCCTGGGAGA GGTGATCAGC CGGCTCCAGA GCACTGCAGA GACCTGGGAC 
CAATGTAAAA AGAAAATCAA GAAGCTGAAA AAGAGGCTGC AGGCTCTGAA GGCACAAAGC 
GAAGATCCCC TTCCTGAGCT TCACGAGGCC CTCCATGAAG AAAAGGAGCT GATTAAGGAA 
GTAGAGAAGT CTCTGGCTAA CTGGACGCAC AGCTTGAAAG AACTTCAGAC TATGAAGGCC 
GACTTGAGCC AGCACATCCT GGCGGAGGAC GTGACGGTTC TGAAGGAGCA GATCCAGCTT 
TTGCACAGAC AATGGGAGGA CCTCTGCCTA AGAGTGGCTA TCCGCAAGCA GGAGATTGAA 
GACAGACTCA ATTCGTGGAT CGTGTTCAAT GAGAAAAATA AAGAACTGTG TGCTTGGCTG 
GTCCAGATGG AAAACAAAGT TCTACAGACA GCAGATGTCA GCATTGAAGA AATGATCGAA 
AAGCTACAGA AAGACTGTAT GGAAGAAATC AGCTTATTCA CAGAAAACAA ACTGCAGCTG 
AAGCAGATGG GCGACCAGCT GATCAAGGCC AGCAGCAAGG CCAAGGCGGC TGAGCTGGAG 
GAGAAGCTCA GCAAGATCAA CGACCGCTGG CAGCATCTCT TTGACGTCAT CGGATCAAGG 
GTGAAGAAGC TGAAGGAGAC GTTTGCTTTC ATTCAGCAGT TAGACAAAAA CATGAGCAAC 
CTTCGTACCT GGTTGGCTCG CATTGAGTCT GAGCTCTCCA AGCCTGTTGT CTACGACGTC 
TGCGATAACC AGGAGATCCA GAAGAGGCTT GCTGAGCAGC AGGATCTGCA GCGAGATATC 
GAACAACACA GTGCAGGGGT GGAGTCTGTG TTTAATATCT GTGACGTCCT TCTGCATGAC 
TCTGATGCCT GTGCCAATGA AACGGAGTGT GACTCAATCC AGCAGACCAC CAGGAGCCTG 
GACAGGCGCT GGAGGAACAT TTGTGCCATG TCAATGGAGC GACGCATGAA AATCGAGGAG 
ACCTGGCGGC TTTGGCAGAA ATTTTTAGAT GACTATTCTC GCTTCGAGGA CTGGCTCAAG 
TCGGCCGAGA GGACAGCGGC CTGCCCTAAT TCCTCCGAGG TGTTGTATAC AAATGCCAAA 
GAGGAGCTGA AACGGTTTGA GGCCTTTCAG CGGCAGATTC ACGAACGACT GACACAGCTG 
GAGCTCATCA ACAAGCAGTA CCGGCGGCTG GCTCGAGAGA ACCGCACCGA CACAGCCAGC 
AAGCTGAAGC AGATGGTGCA CGAGGGCAAC CAGCGCTGGG ACAATCTGCA GAAGCGGGTC 
ACAGCCATCC TGCGGAGACT CAGGTACTTC ACCAACCAGA GGGAAGAGTT TGAGGGCACC 
AGGGAGAGCA TTCTGGTTTG GCTCACAGAA ATGGACCTGC AGCTGACCAA CGTAGAACAC 
TTCTCAGAGA GTGACGCTGA GGACAAGATG CGCCAACTGA ACGGCTTCCA ACAGGAGATC 
ACACTGAACA CCAACAAGAT CGACCAGCTC ATCGTGTTTG GGGAGCAGCT CATTCAGAAG 
AGTGAGCCCC TCGACGCCGT CCTGATCGAG GACGAGCTAG AGGAGCTGCA CCGCTACTGT 
CAGGAGGTGT TCGGCAGAGT GTCTCGCTTC CACCGCCGCC TGACCTCCCA CACCCCGGGC 
TTAGATGATG AGAAGGAGGC GTCTGAGAAT GAGACGGACA TAGAAGACCC CAGGGAGATC 
CAGGCTGACT CTTGGCGTAA GAGGAGAGAG AGCGAGGAGC CCACATCTCC CCAGTCACTG 
TGTCACCTTG TGCCTCCGGC TCTGGGACAT GAGCGGTCTG GCTGTGAGAC CCCCGTCAGT 
GTGGACTCTA TCCCTCTGGA GTGGGATCAC ACAGGTGACG TGGGGGGATC CTCTTCTCAT 
GAAGACGACG AGGAGGGCCC ATTCTACAGC GCACTGTCAG GTAAATCCAT TTCTGAGGGC 
CACCCGTGGC ATGTTCCTGA CAGCCCTTCC CATTCCAAGC ATCACTACAA ACACATGGAA 
GGTGACAGGA CTGAGGCACC AGTCCCCACA GATGCCAGCA CGCCTTTCAA ATCAGACTAT 
GTAAAGCTGC TATTACGTCA AGGCACCGAT GACAGCAAAG AAGGCTTAAA GGAGGCTCAG 
CAGGAAGATG AGCAGCTGGC CACTTTAACG GGACAGCAGC CAGGTGCCTT CGACAGGTGG 
GAGCTGATCC AGGCGCAGGA GCTTCACAGC AAGCTCAGGC TCAAACAGAC CGTGCAGCAG 
CTCAAGTCTG ACATCGGCAG CATCGCTGCT TGGCTTGGGA AAACTGAGGC CGAGCTGGAA 
GCTCTGAAGT TGGCCGAGCC TCCCTCTGAC ATCCAGGAAA TAGCGCTCAG GGTGAAGAGA 
CTGCAAGAGA TACTAAAAGC CTTCGATACC TACAAGGCCT TGATGGTCTC CGTCAATGTG 
AGCCACAAGG AATATCTGCC AAGCCAGAGC CCCGAAGCCA CAGAACTCCA AAATAGACTC 
CATCAGCTGA GCCTGTCCTG GGACTCGGTC CAGGGCGTAT TGGACAGCTG GCGAGGAGAC 
TTACGGCAGT CACTCATGCA GTGCCAGGAC TTTCACCAGC TGAGTCAAGA CTTGCTCCTG 
TGGCTAGCGA CAGCAGAGAG CCGCAGGCAG AAGGCGCATG TCACCAGCCC AGAGGCCGAC 
CGCCAGGTCC TCCTGGAGTG TCAGAAAGAC CTAATGCGCC TAGAAAAGGA GTTGGTAGCC 
CGTCAGCCTC AAGTCAGCTC CTTGCGGGAG ATTTCCTCCA GCCTTCTGGT GAAGGGGCAA 
GGAGAAGACT ACATTGAGGC CGAAGAGAAG GTCCACGTGA TCGAGAAGAA ACTCAAGCAA 
CTGCAAGAGC AAGTGGCTCA AGATCTGATG TCCTTGCAGA GAAGCCTGGA TCCGGATGCT 
TCTCTAACCA GCTTTGATGA GGTGGACTCA GGAGAACAGC TCCCAGCAGC CTTTGCAAAG 
AGTCCAAGGC CCCGCTGGAC CTTCTTGGAA GAGGAAGAGG AGGAGGAGGA GACAGACAGC 
AGGATGCCCC ACCTCGACAG CCCCGGCAGC TCCCAGCCGA GACGCTCCTT CCTCTCAAGG 
GTGATCAGGG CAGCGCTACC GTTGCAGCTG CTTCTGCTGC TGCTGCTGCT CCTGGCCTGC 
CTGCTACCTG CCTCTGAAGA TGACTACAGC TGCACCCAGG CCAACAACTT TGCCCGATCC 
TTCTACCCCA TGCTGCGGTA CACCAACGGG CCACCTCCCA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005510.2
CDS	210..20834
Translation	MAASPVLPTEDGEGFLGIDDLHFSLQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGSNTFQCRINIEHALTFLKNRSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKLAQTLSCDYNQPSPEVVSVAASSPTSSPPTKKCSKAQAQARWQWSAKKALLQWAQEQCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKEAFRIAEHELKIPKLLEPEDVDVVNPDEKSIMTYVAQFLKYSKDAPGPGDSTQAKVRDALVWLTLQEKRFQKMLKDSASETYCNKYHSLLSFMESLNEEKESFIDVLSLKGRMGELNEDESRLRQGWTSLMHQVAAWRAQLDDALPSPLKETEAWLKDIEGVVQEGVPTSQSYSEARTLIQGKLSSFKSLMGSFDYHSDVLMAFQSNAEKSLPAVPPVKLEEMTRRINNVLGKNFIPLLEFHDSKCSVLALLDEAKAKLDVWNGTYESKESVEVLLEDWHKFTGEKKFLIQLDASFQKCEEMYKNSARECESIREEYMMLEKNVHSCRQYIHNTKATLQRALMSWATFEEDLALLKASFDLTKKEQIKEVPVETLLQWNTKHTSLNEVGSFLIGVSSREVAASISKELRRLNKRWRKFITKTPLLKLPLVKIQDQPPGNSSGTSLSKESAMAAEPGGSRGEDVKAAEKQEVEDEESAGQLKVNEEVEGLIKQVTIWESQTKSILDLLQHGDHADGSSADTLQHLIAKGSVYEELLARTEDTLQMDVQSPSNLEPFQNVLRAGLQAKIQEAKQGVQITMVELSAVLKNLSDEPLELDLGLKVEEAQKELEVSILRAEQLLGQRERPGGFLLKYKEALEILNTNSLAKYLRAVEELKRTVPGGAKLQLEEQSRVASAKWEPLRHEISLYLQQLKIAIEEEKLRDNIARLEKQINKEKKLIRRGRTRGLRKEHEACLSPESIKCQLEHHVGVLRVLCEELTSPEDQQELKRALRDYEQKIARLLKCASEIHTTLQSSQGGALEERSALITTENGRRDADGEVPLEIPDNQLSTEKAMEPIKNFSQTSELKPQQEESIMEKEGKDCSASLSDLQERYDTQRGLLEQHLQDSKSRVTSDFASEQERSSACLQSKLAELQVLLADTDAHWEKFEITSLNLRRLMSDAEKPVLNQERDLLKGNEQVLHGLLNTRMESLEMALQIVLPLEKECSLLCASDLPLCTVAVQDLHPVEIDGVYQNLRDIRDSIAKQIRVCTSLEEPSNSVPRELHTLDQCAIQDIVLKCRLQLETMNQKVEMREDALDALEGFLASLRAAKLSAELPADRPAPKAPEVLSEDILLMKEKAGPLDERLRTLGINIKDAEGGENTTCERLVGALSVNLVAMDGQSKEEGPPEDKKLLEACSSKNLELFKNIQDLQNQISKIGLKDPTAPAVKHRKKSLLRLDKDLDGLEEEKVRIQKIAGSLPRFKDGSEKNVIQQCEDTAALWESTKASVTESLEQCGSALELLRQYQNIKNNLTALIQKEEGIISQQASYMGKDNLKKKIAEIETVKEEFSDHLEVVDKINQICKNLQYHLNKMKTFEDPPFEKEANAIVDRWLDINEKTEEYGENLGRALALWDKLFIIKNNIDEWTEQILGKAESHELTEEDRGRLKEELKVLEEQSAEFSRRVADIQSLLQSNEKPLELQVMESSVLSKMKDVKTHVAGGSNSYAPSGSTAELREDLDQAKTQMGMTESLLNALSPSDSLEIFTKLEEIQQQIFQQKHSMTVLENQIGCLTPELSELKRQYASVSNLFNTKKNALQDHFATFLNEQCKNFNDWFSNVKTNLQECFEPPETKLSLEQRLQKLSDFLTLGGGNSKIQQVETVLQHVKMLLPKAHVKELDSWLRSQELELENMESICQARAGELNNSFQQLLRLEDDCRSLSKWLTNQEENWGKMEVSGERMDLFSQALTRKREQFETVAQLSDSLKEHGLTEGEETIKESTHLIDRYQALWRQLHEIEEEDKLPAAEDQSFNDLADDVIHWIKEIKESLMALNSSEGKMPLEERIQKIKEIIALKPEGDAKIQMVMRQAEHCEAPLAQETFTDLSNQWDSTLHLANTYLSHQEKLVLEGEKYLQSKEDLRLMLTELKKQQEAGFALQPGLPEKQAQLKIYKKFLQKAQDLTSLLEELKSQGNYLLECTKNPSFSEEPWLEVKHLHESLLQQLQDSVQKLEGHVQEHSSYQVCLTDLSSTLDDISKEYFSLCDGSKDQIMAKERMQKLQELESRLRFQGGALKKASALAKSIKQNTSSVGQKIIKDDIRSLKYKQKDLENRIESAKQETENGLNSILKSKSSTEKHVKFSLPVEEMPATSEVPKPTRESAAVGESGGARETNTNSAVEMILSKQLSLNVQESMQNAQDEREVNELQNQPLELDIMLRNEQLKGMEELSTHLEARRAAIELLEQSQHLNQTEEQALVLPAARPSVCHLGSLQQELHTLKKTKERQYGLLSGFQDQLVMAEASLNTSLAEVESLKIGSLDSATYLGKIKKFLGSVENQQGSLSKLRTEWAHLSSLLAAADQKLVESQMKHLEHGWELVEQLAHRKCFQQATEHSELTCLLEKLQDLKVSLHQQQQRLTLSLNSPGQQAAIVDMVTPAAELQAIKCEFSGLKWQAELHMKRLWGEKDKKTLEDAINNLNKQMEALEPLNREVENRIKKCELQNRIKETLSWVKNTMAELVVPIALLPDNILSQIRKCKLIHDGILGNQQAVELLVEEVRGITPSLAPCEGDGLNALLEDLQSQHQALLLKSTERSQQLELKLEEKSKLFAIIGKVQLTLEESETLMSPTGDRASTEAELERRLAILKASQQQLQDTESALSAHLQELTNAYKDANVFERLFLDDQLKNLKARTNRTQRFLQNNGSELKQKMESYREFHDKAAVLQKEAECILHGGLLPLRQELEQDAKEQLGNLRDKLAAIRGSLSQVLTSEEVFDTIGLSWDGSLLARLQTQVLEREREVEGKIKQLDTFLIARDRHQASISKIRAVDLQIKKGAESLLKVPSMSPESTLLNAQTLIQKIEKSKRLRDEIIRKLSKNEAFDDSFKESEMQRLKLCAEENSRLQEALQNMLLELQPREMGEKEFREKLENALHVLKQIQSRLQQPLCVNLGVQHIQHEKETWEAFGEQVEAEMCGLRAVRITEEQREENDSGTGGMEAKLRDIEGLHMELSKSISLRADVLNDAYDSANRYDELVAGALRIITSLEATLLSYRVDLHNPQKTLELAHLKQEELQSSVADLRSLTETLGAISSPEAKEQLRCTLEVLAAKNSALKAGLEAQEAEEERCLENYKCFRKMKEEICSRLRKMEMDLGQSIFPLPRSYKEALARLEQSKALTSNLLSTKEDLVKLRQLLRHLRCRSTENDATCALGVASALWEKWLSLLEAAREWQQWGGELKREWKFISEEIEREAIILETLQEDLPEISKTNAAPTEELWQLLDSLCQHQESVEKQQLLLALLLQRVRSIQNIPEGTETGETIPALQEIGSMQERCDRLLHTTRKNKDLVQAEIQAQQSFLKEIKDVKRVFEQISTSFPNLAPEGHPERAEQFEELRSILQKGKLSFENIMEKLRIKYSEMYSIVPAEIGSQVEECRSALEDAEEKMSSEVSKSSPSSIMRRKIERINNGLHCVEKMLQQKSRNIEEAHEIQKKIWDELDLWHSKLNELDSEVQDFVEQDPGQAQEWMDNLMAPFQQHQQVSQRAESRTSQLNKATIKMEEYNDLLKSTEVWIEKTSCLLANPACYDSSRTLSHRASTLQMALEDSEQKHSLLHSIFTDLEDLSIIFETDDLIQTIHELSDQVAALQQQIMEALPHVQQVADDVVAIESEVKAMEKKVAKIKAILLSKEIFDFPPEEHLKHGEVILENIHPMKKTIAEIMTYQVELRLPQTGTKPLPVFQRTSQLLQDVKLLENVTQEQNELLKVVIKQTAECDEEIDSLKQMLTNYSAEISPEHVSQNQVADLPSLQGEMERLEKQILNLNQKKEDLLVDLKTAVLNLHEHLKQEQQEVGDKPSAGASECTVAERDASERKLSRTNSMSFLPVVKEEAEESSVKSEDGRRRTEPPSASWSFLGKHSKDLEGDGASSSSSATIVQDADGRISTCDSSMVHIIAPDSGSTEEGPAPSPRLSQTDEGATPPIEAALLDFPREQGAFESTVERSRPRPADILRVCKTQVAKLELWLQQANVAFEPETVDADMQQVVEEELAGCQAMLTEIEYKVASLLETCKDQGLGDCGTTQQEAEALSWKLKTVKCNLEKVQMVLQEKFSEDQHPSTLKKPSEPHDVDQPAGLSELDSVLTERPQFSRQKDAPQPQILELKPSEQKDLIKFTELNAKKTWLQGHQENEDANRQSASSSKVPSPGNAASDSTLPLQAQSGDKWQYLHHELTSRPNPSVPQLVEPQVALTTSTLPSVSVYNFRCPTADELQAYTTQLEELRQEANTIQTQGSMTEETYISLDKRLFELFLSLSRCLGSVEGLLQRPGLLREDACAQQVFFQKLALELKKLYLALGDKKDDFLKAVTWPGKEATLLPECIDALTVSLESVQSRAAWRDASLKAGLEHSRSYQNEVKRLYSQLIKKKTALQQSLNEISGQSISKQLQKADVHTAELQNSEKQVAKLRDEGERLRFPHGLLQDVYKLEDVLDSMWGILRARYLELSSPFLSKSLQTLLQGMAELVSIGKGKLAADPLQHAKSKAALQAQLQDHKAFFQKLVADMLLIQTYSATMFPPSLQKGEGFGAEQVAEVRALEEEACLRGAQLQSMLQKWEEFDDNYASLEKDLEALISSLPSVSLVEETEERLLERISFYQQIKRNIDGKHARLCQTLNEGRQLAASVSCPEPEGQIARLEEQWLSLNKRIDQELHRLQTLLKHLLSYSRDSDELTRWLETSQQTLNYWKEQSLNVSQDLNTIRSNIDRFFKFSKEVDERSSLKSAVMSTGNQLLHLKEADTATLRASLAQFEQKWTVLITQLPDIQEKLHQLQMEKLPSREAISEMISWMNAVEPQAAGKDTELSKSSASQVKHLLQKLKEFRMEMDYKQWVVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWQRVHGTLNRKIQHLEQLLESITENENKVQNLNSWLEAQEERLKMLQKPESAVSMEKLLLDCQDIENQLALKSKALDELRQSSLTMDGGDVPLLEDMASGIVELFQKKNNVTSQVHQLRASVQSVLQEWKACDKLYDEATMRTTQLTYSMEHSKPAVLSLQALACQVQNLEALQDEAENGERSWEKLQEVIGRLKASCPSMAGIIEEKCQDAHSRWTQVNQDLADQLQEARGQLQLWKAPHNAHAEAAAWLQQQEAKFQQLANTNLSGDNLADILPRALKDIKGLQSDLQKTKEAFLENSTLSDQLPQPEERSTPGLHSGQRHSLQTAAYLEKMLLAKSNEFEIVLAQFKDFTDRLAYSKDLIVHKEENLNKLYHEEKEEVPDLFLNHVLALTAQSPDIERLNEESLRLPLSDVTIKTLQSLNRQWIRATATALDHYSELQGNGLNEKFLHYCERWIQVLEKIQESLSVEVAHSLPALLEQQKTYEILEAEVSTNQAVADAYVTQSLQLLDTAEIEKRPEFVSEFSKLSDQWQRAARGVRQRKCDISRLVTQWRFFTTSVEDLLRFLADTSQLLSAVKEQDCYSLCQTRRLVHELKSKEIHLQRWRTTYALALEAGEKLRNTPSPETREFVDGQISRLQESWKDTELSLGEVISRLQSTAETWDQCKKKIKKLKKRLQALKAQSEDPLPELHEALHEEKELIKEVEKSLANWTHSLKELQTMKADLSQHILAEDVTVLKEQIQLLHRQWEDLCLRVAIRKQEIEDRLNSWIVFNEKNKELCAWLVQMENKVLQTADVSIEEMIEKLQKDCMEEISLFTENKLQLKQMGDQLIKASSKAKAAELEEKLSKINDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDNQEIQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTNAKEELKRFEAFQRQIHERLTQLELINKQYRRLARENRTDTASKLKQMVHEGNQRWDNLQKRVTAILRRLRYFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDAEDKMRQLNGFQQEITLNTNKIDQLIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSHTPGLDDEKEASENETDIEDPREIQADSWRKRRESEEPTSPQSLCHLVPPALGHERSGCETPVSVDSIPLEWDHTGDVGGSSSHEDDEEGPFYSALSGKSISEGHPWHVPDSPSHSKHHYKHMEGDRTEAPVPTDASTPFKSDYVKLLLRQGTDDSKEGLKEAQQEDEQLATLTGQQPGAFDRWELIQAQELHSKLRLKQTVQQLKSDIGSIAAWLGKTEAELEALKLAEPPSDIQEIALRVKRLQEILKAFDTYKALMVSVNVSHKEYLPSQSPEATELQNRLHQLSLSWDSVQGVLDSWRGDLRQSLMQCQDFHQLSQDLLLWLATAESRRQKAHVTSPEADRQVLLECQKDLMRLEKELVARQPQVSSLREISSSLLVKGQGEDYIEAEEKVHVIEKKLKQLQEQVAQDLMSLQRSLDPDASLTSFDEVDSGEQLPAAFAKSPRPRWTFLEEEEEEEETDSRMPHLDSPGSSQPRRSFLSRVIRAALPLQLLLLLLLLLACLLPASEDDYSCTQANNFARSFYPMLRYTNGPPPT

Target ORF information:

RefSeq Version	NM_001005510.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus spectrin repeat containing, nuclear envelope 2 (Syne2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005510.2

ORF Insert Sequence:

ATGGCCGCTA GCCCTGTGCT GCCCACGGAA GATGGAGAGG GTTTCTTGGG CATTGATGAT 
CTACACTTTT CACTGCAAGC TGAGCAGGAG GACACTCAGA AGAAAACCTT CACCTGCTGG 
ATAAACTCAC AGCTGGCAAA GCACACACCT CCCTCAGTTG TATCTGACTT ATTCGCAGAC 
ATCAAGAAGG GGCATGTCCT CCTGGACCTG TTGGAAGTCC TCTCGGGACA GCAGTTGCCT 
CGGGATAAAG GATCTAATAC ATTCCAGTGC AGAATCAACA TAGAACATGC CCTGACATTC 
CTGAAAAACA GATCTATCAA GCTAATAAAT ATCCATGTTG CTGACATTGT AGAAGGAAAC 
CCGTCCATTA TCCTTGGCCT GATCTGGACC ATCATCCTGC ACTTTCATAT TGAGAAGCTC 
GCTCAGACTC TGTCTTGCGA TTACAATCAA CCTTCACCGG AGGTTGTGAG CGTGGCTGCC 
TCATCTCCTA CCTCAAGTCC TCCCACTAAG AAGTGCTCCA AGGCTCAAGC TCAGGCAAGA 
TGGCAGTGGT CTGCCAAGAA GGCTCTTCTG CAGTGGGCTC AGGAGCAGTG TGCCAGGTCT 
GAGTCTGTCA ATGTGACAGA TTTTAAGTCA AGCTGGAGAA ATGGGATGGC TTTTTTGGCT 
GTCATTCATG CCTTGCGACC AGACCTGATT GACATGGACA GCATGAGGCA CAGATCCAAC 
AAAGACAATC TGAAAGAGGC CTTCAGGATC GCAGAACATG AGCTGAAGAT CCCCAAATTG 
CTGGAACCAG AAGATGTAGA TGTCGTGAAT CCTGATGAGA AGTCCATCAT GACTTACGTG 
GCGCAGTTCC TGAAGTATTC GAAGGATGCG CCTGGCCCCG GGGATTCCAC ACAGGCCAAG 
GTAAGGGATG CTCTGGTCTG GCTAACTCTG CAAGAGAAGA GATTCCAGAA GATGCTGAAG 
GACTCAGCAA GTGAGACCTA CTGTAACAAG TATCATAGTC TGCTGTCATT TATGGAGTCA 
CTGAATGAAG AAAAGGAATC CTTCATTGAT GTCCTGTCAC TGAAAGGGAG GATGGGAGAG 
CTGAATGAAG ATGAATCACG GCTGAGACAA GGCTGGACCA GCCTCATGCA CCAGGTCGCT 
GCGTGGAGAG CCCAACTGGA TGACGCCTTG CCTTCACCGC TCAAAGAGAC CGAAGCGTGG 
CTGAAGGACA TAGAGGGTGT TGTGCAAGAA GGGGTGCCGA CCTCCCAGAG TTACTCTGAA 
GCCAGGACTC TGATCCAAGG GAAACTATCT TCATTCAAGA GTCTGATGGG CAGCTTTGAC 
TATCATTCGG ATGTTCTCAT GGCCTTTCAA TCCAATGCCG AGAAGAGCCT GCCAGCTGTG 
CCTCCTGTTA AACTGGAGGA GATGACAAGA CGAATCAACA ACGTTTTGGG TAAAAACTTC 
ATCCCACTCC TGGAGTTTCA TGACTCTAAG TGCTCAGTTC TGGCTTTGCT TGATGAAGCG 
AAGGCCAAGT TGGATGTCTG GAACGGCACT TATGAGAGCA AGGAGTCTGT GGAAGTCCTG 
CTGGAAGACT GGCATAAATT TACTGGAGAA AAAAAGTTCC TAATTCAACT TGATGCTTCT 
TTTCAAAAAT GTGAAGAAAT GTATAAGAAC TCGGCCAGAG AATGTGAGAG TATTAGAGAG 
GAGTATATGA TGCTGGAAAA GAATGTTCAC TCGTGCAGAC AATACATCCA TAACACGAAG 
GCCACACTGC AAAGAGCACT GATGTCTTGG GCAACTTTCG AGGAAGATCT CGCCCTACTA 
AAGGCTTCTT TTGACTTGAC AAAGAAGGAA CAAATTAAAG AGGTTCCCGT TGAGACCCTC 
TTGCAGTGGA ACACAAAACA CACATCTTTG AATGAGGTGG GGAGTTTCCT GATTGGAGTC 
AGCAGTAGAG AAGTTGCCGC ATCTATTTCT AAAGAACTGA GAAGGCTCAA TAAAAGATGG 
AGAAAGTTCA TCACCAAAAC TCCACTTCTG AAACTGCCAC TCGTGAAAAT TCAGGACCAG 
CCCCCTGGGA ACAGTTCTGG AACGAGTCTG TCTAAGGAGT CAGCTATGGC AGCAGAGCCT 
GGTGGAAGCC GTGGTGAGGA TGTAAAGGCT GCGGAAAAGC AGGAAGTAGA AGACGAAGAG 
TCAGCCGGAC AATTGAAAGT GAACGAAGAA GTTGAAGGAC TCATCAAGCA GGTGACAATC 
TGGGAGTCAC AAACCAAATC CATCTTGGAT CTCCTCCAAC ATGGAGACCA TGCCGATGGC 
TCCTCAGCAG ACACCTTGCA GCATCTTATT GCTAAAGGCT CTGTGTATGA GGAACTTCTG 
GCCAGAACCG AAGATACTTT ACAGATGGAT GTTCAAAGTC CTTCGAACCT GGAGCCCTTC 
CAAAATGTCC TCAGAGCTGG CCTTCAGGCA AAGATCCAAG AAGCTAAACA AGGAGTTCAG 
ATCACCATGG TAGAATTGTC TGCAGTGTTG AAGAACTTAA GTGATGAACC ACTGGAGCTA 
GACCTGGGGC TAAAGGTGGA GGAAGCGCAG AAGGAGCTGG AGGTCTCCAT CTTGAGAGCC 
GAGCAGTTAC TCGGGCAAAG AGAGCGCCCT GGTGGATTCC TCTTGAAGTA CAAGGAAGCA 
TTGGAAATTC TTAATACCAA TAGTCTGGCC AAGTATCTTC GAGCTGTTGA AGAACTGAAG 
CGTACTGTCC CCGGTGGTGC GAAGCTGCAG CTGGAAGAAC AGAGTCGAGT CGCAAGTGCC 
AAGTGGGAGC CGCTCCGTCA TGAAATTTCT TTGTATCTCC AACAACTAAA AATAGCTATT 
GAAGAAGAAA AGCTTAGAGA CAATATTGCG AGACTTGAAA AGCAAATAAA TAAAGAAAAG 
AAGCTTATCC GGAGAGGCAG GACCAGGGGC CTCCGCAAGG AGCACGAGGC TTGCTTGTCT 
CCGGAAAGCA TCAAGTGCCA GCTAGAACAC CATGTGGGTG TCTTGAGGGT GCTGTGCGAG 
GAGCTGACAT CACCAGAGGA TCAACAAGAA TTGAAGAGAG CACTCCGAGA TTACGAACAA 
AAGATAGCGA GACTTCTGAA ATGTGCTTCT GAGATTCACA CAACCCTGCA GTCCTCCCAG 
GGAGGTGCAT TGGAGGAGAG GAGTGCCTTG ATCACAACTG AGAATGGCAG AAGGGATGCC 
GATGGCGAGG TACCACTTGA GATACCAGAC AACCAGCTGT CAACTGAAAA GGCGATGGAA 
CCCATTAAGA ATTTTAGCCA GACATCAGAA TTAAAGCCTC AGCAAGAAGA AAGCATTATG 
GAGAAGGAAG GAAAGGATTG CAGCGCCTCT CTAAGTGACT TACAGGAGAG GTATGACACA 
CAAAGGGGGC TTCTTGAGCA ACACCTGCAA GACAGCAAAT CCAGGGTGAC GTCTGACTTT 
GCCAGTGAGC AGGAGAGGAG CAGCGCCTGC CTGCAGAGTA AACTGGCAGA ACTGCAGGTC 
TTACTGGCTG ACACTGATGC TCACTGGGAG AAGTTTGAAA TCACTTCACT GAATTTAAGA 
AGACTGATGA GCGACGCGGA GAAGCCTGTG CTTAACCAGG AGAGAGACTT ATTAAAGGGG 
AATGAACAGG TTCTTCACGG GCTTCTTAAC ACCAGAATGG AGTCACTGGA GATGGCGCTG 
CAGATAGTAC TTCCTCTGGA GAAGGAGTGT TCTCTCCTGT GTGCCTCTGA CCTGCCCCTC 
TGCACAGTGG CTGTCCAGGA CCTGCATCCT GTTGAGATTG ATGGTGTCTA TCAGAACCTG 
CGGGATATCC GAGATTCCAT CGCAAAGCAG ATCAGAGTCT GTACCAGTTT GGAGGAGCCG 
AGTAACTCTG TACCAAGGGA GTTACACACA CTAGATCAGT GTGCGATCCA GGACATTGTG 
CTGAAGTGCA GACTCCAGCT GGAGACCATG AACCAGAAGG TAGAGATGAG GGAGGATGCC 
CTGGATGCTC TGGAAGGGTT TTTGGCATCT CTGAGAGCAG CTAAGCTCTC TGCTGAGCTC 
CCTGCAGACC GTCCTGCCCC GAAAGCACCA GAAGTGCTGA GTGAAGACAT TCTCCTGATG 
AAAGAGAAGG CCGGGCCTTT GGATGAACGC CTGAGGACAC TTGGCATAAA CATTAAGGAT 
GCCGAGGGAG GGGAGAATAC CACCTGTGAA AGACTGGTCG GTGCATTGTC AGTAAACTTA 
GTGGCCATGG ATGGCCAGAG TAAAGAGGAA GGACCTCCTG AGGACAAGAA GTTACTGGAA 
GCTTGTAGTT CCAAAAATCT CGAGCTCTTT AAAAACATTC AAGACCTCCA GAATCAGATC 
AGTAAAATTG GTCTTAAGGA TCCTACTGCT CCAGCCGTGA AGCATCGGAA AAAGTCATTA 
CTCAGGCTGG ATAAGGACCT AGATGGATTG GAAGAAGAAA AGGTGCGCAT ACAAAAAATA 
GCTGGCTCTC TCCCACGATT CAAGGATGGC AGTGAGAAAA ACGTGATTCA ACAGTGTGAA 
GACACAGCAG CCTTGTGGGA GAGTACGAAA GCTTCTGTCA CAGAGAGCCT TGAACAGTGT 
GGAAGTGCTC TGGAGCTCTT ACGACAATAT CAGAATATTA AAAACAACTT GACAGCTTTG 
ATTCAGAAGG AAGAGGGCAT CATCTCCCAG CAAGCTTCCT ACATGGGAAA GGACAACCTG 
AAGAAGAAGA TAGCCGAGAT TGAAACTGTC AAAGAAGAAT TCAGCGACCA TTTAGAAGTT 
GTAGACAAGA TAAATCAGAT TTGTAAAAAC CTACAATATC ATCTGAATAA AATGAAAACC 
TTTGAAGACC CCCCCTTTGA AAAAGAGGCT AATGCTATTG TGGACAGATG GCTTGATATT 
AATGAGAAGA CAGAAGAATA TGGTGAAAAT CTTGGCCGAG CGCTGGCCTT GTGGGACAAA 
CTTTTCATCA TAAAAAACAA CATCGATGAG TGGACTGAAC AGATCCTTGG GAAAGCAGAA 
TCCCATGAGC TGACTGAGGA GGACAGAGGA AGGCTGAAGG AAGAGTTAAA AGTACTCGAA 
GAGCAAAGTG CAGAATTTTC TAGAAGAGTG GCTGACATAC AGTCGTTGCT TCAGAGCAAT 
GAGAAACCAC TTGAACTGCA GGTCATGGAG TCCTCTGTCC TGAGCAAGAT GAAAGATGTG 
AAAACACATG TCGCAGGGGG ATCCAACAGC TATGCGCCCA GTGGGAGCAC AGCTGAGCTG 
AGAGAGGATC TGGACCAGGC CAAGACCCAG ATGGGGATGA CTGAGTCCCT CCTGAATGCC 
TTGTCTCCCT CTGATAGCCT GGAGATCTTC ACAAAGCTTG AGGAAATCCA ACAGCAGATC 
TTTCAGCAGA AGCACAGTAT GACGGTCCTG GAAAATCAAA TAGGGTGCCT CACTCCAGAG 
CTCTCCGAAC TGAAAAGACA GTACGCAAGT GTCAGCAATC TATTTAATAC CAAAAAGAAC 
GCGCTGCAGG ACCACTTTGC CACGTTCCTG AACGAGCAGT GTAAGAACTT TAACGACTGG 
TTCAGCAACG TCAAAACGAA TCTTCAGGAG TGTTTTGAAC CACCAGAAAC AAAACTGAGC 
CTGGAACAAA GGCTGCAAAA ACTTTCTGAT TTCTTGACTC TTGGAGGAGG AAACAGTAAA 
ATACAGCAGG TAGAGACCGT CCTACAGCAT GTGAAGATGC TCTTACCCAA AGCACACGTG 
AAGGAGCTTG ACAGCTGGCT CAGGAGTCAA GAACTGGAAT TAGAAAATAT GGAGTCCATA 
TGCCAGGCCC GAGCAGGGGA ACTGAATAAC TCCTTTCAGC AGCTACTGAG ATTGGAAGAT 
GATTGCAGAA GCCTAAGTAA GTGGCTGACT AATCAAGAAG AGAACTGGGG AAAAATGGAA 
GTATCAGGAG AGCGAATGGA TCTGTTTTCC CAAGCATTGA CTAGGAAGAG GGAGCAGTTT 
GAGACTGTGG CCCAGCTAAG TGACTCTCTG AAGGAGCATG GGCTCACCGA GGGAGAAGAG 
ACAATCAAAG AATCCACACA TCTGATCGAT AGATACCAGG CTTTATGGAG ACAATTACAC 
GAAATTGAGG AAGAGGATAA GTTACCAGCG GCCGAAGACC AGAGCTTTAA CGATCTTGCT 
GATGATGTAA TTCACTGGAT AAAAGAGATT AAAGAGTCCC TTATGGCTTT GAATTCATCA 
GAAGGCAAAA TGCCACTCGA AGAAAGAATC CAAAAAATAA AGGAAATCAT TGCCTTGAAG 
CCAGAAGGAG ATGCTAAGAT CCAGATGGTA ATGAGACAAG CGGAACACTG TGAGGCCCCG 
CTGGCTCAAG AGACCTTTAC GGACCTCAGC AACCAGTGGG ACAGCACGCT CCACCTCGCC 
AACACATACC TCAGCCATCA AGAAAAGCTT GTACTAGAAG GAGAAAAGTA TTTGCAGAGT 
AAGGAGGACC TGAGGCTGAT GCTCACAGAG CTGAAGAAGC AGCAAGAAGC AGGCTTTGCT 
CTACAGCCTG GGTTGCCAGA GAAGCAGGCC CAGTTAAAAA TTTATAAGAA ATTCCTCCAG 
AAAGCCCAAG ATTTGACATC CTTGCTAGAG GAGCTAAAAT CTCAGGGCAA TTACCTCTTG 
GAGTGCACTA AAAATCCCAG CTTCAGCGAG GAGCCGTGGC TAGAAGTGAA GCACCTGCAT 
GAGAGCCTTC TCCAGCAGCT CCAGGATTCT GTGCAAAAAT TAGAGGGTCA TGTTCAAGAA 
CACAGTTCCT ACCAGGTTTG CCTCACAGAC CTAAGCTCCA CACTGGATGA TATCTCCAAG 
GAATATTTCA GTCTTTGTGA TGGATCTAAG GACCAAATAA TGGCTAAGGA GAGAATGCAG 
AAGTTACAGG AGCTGGAGAG CAGACTCCGT TTCCAAGGCG GTGCGTTAAA GAAGGCTTCT 
GCTTTAGCGA AATCCATCAA GCAAAATACA TCTTCAGTGG GACAGAAGAT TATTAAAGAT 
GACATAAGAT CGCTTAAGTA TAAACAAAAG GATTTGGAAA ACAGAATCGA ATCTGCCAAG 
CAGGAGACTG AAAACGGTCT CAACAGCATC CTTAAATCCA AAAGCTCAAC AGAAAAACAT 
GTAAAGTTTT CTCTGCCAGT TGAAGAGATG CCGGCCACTT CTGAGGTGCC CAAGCCCACT 
CGGGAGTCGG CAGCCGTGGG CGAGTCAGGA GGAGCCCGGG AAACAAACAC GAACTCAGCT 
GTGGAAATGA TTTTGTCAAA ACAACTTTCT CTCAATGTTC AAGAAAGCAT GCAAAACGCC 
CAAGATGAGC GGGAAGTCAA CGAGCTGCAG AATCAACCTT TAGAATTGGA CATTATGTTA 
AGAAATGAAC AATTAAAAGG GATGGAGGAA TTATCTACTC ACTTAGAAGC AAGAAGAGCA 
GCCATTGAAC TTCTGGAACA GTCGCAGCAT CTCAACCAAA CAGAAGAGCA AGCCTTGGTT 
CTGCCCGCCG CCAGACCTTC AGTGTGCCAC TTGGGCAGTC TACAGCAGGA GCTTCATACC 
TTGAAGAAAA CTAAAGAAAG ACAGTATGGC CTCCTTAGTG GTTTTCAAGA CCAGCTGGTG 
ATGGCTGAAG CCTCCCTGAA CACCTCCTTG GCAGAAGTGG AAAGCCTCAA AATAGGCTCG 
CTAGACAGTG CAACCTATCT GGGGAAAATC AAGAAGTTCC TGGGGTCCGT GGAAAACCAG 
CAAGGCTCAC TGAGCAAGCT TCGCACCGAG TGGGCACATT TATCCAGCCT CCTGGCGGCC 
GCAGACCAGA AGCTGGTGGA GAGCCAAATG AAGCACCTTG AACATGGGTG GGAACTTGTG 
GAGCAGCTGG CTCACAGGAA GTGTTTCCAG CAAGCCACAG AACACAGCGA ACTCACCTGC 
CTCCTGGAGA AGCTCCAGGA CCTTAAGGTT TCTCTGCATC AGCAGCAACA GCGCCTAACG 
CTAAGTCTGA ACTCTCCAGG ACAACAGGCG GCGATCGTGG ACATGGTCAC TCCAGCCGCT 
GAGCTCCAGG CAATCAAGTG TGAGTTTTCT GGCTTAAAGT GGCAAGCTGA GCTTCACATG 
AAGAGGCTTT GGGGAGAAAA GGATAAGAAA ACTCTGGAAG ATGCAATAAA TAATTTGAAT 
AAGCAAATGG AAGCACTGGA GCCGTTAAAC CGAGAGGTAG AAAATCGGAT TAAAAAGTGT 
GAGCTCCAGA ACAGGATAAA GGAGACTCTG TCCTGGGTCA AGAACACGAT GGCGGAGCTC 
GTTGTTCCCA TCGCCCTTCT CCCTGACAAC ATCCTTTCTC AGATCAGAAA GTGCAAGCTG 
ATTCACGATG GCATTCTGGG TAACCAGCAG GCAGTGGAGT TGCTGGTGGA AGAGGTCAGA 
GGCATCACCC CCAGCCTTGC ACCATGTGAG GGTGACGGTT TAAATGCTCT CCTGGAGGAT 
TTACAGAGCC AACACCAAGC ACTGCTTTTA AAATCAACTG AGAGGTCCCA GCAACTAGAA 
CTGAAGTTGG AAGAAAAAAG CAAACTGTTT GCGATTATAG GTAAGGTTCA GCTCACGCTT 
GAAGAAAGCG AAACACTGAT GTCGCCCACG GGGGACAGAG CCTCCACGGA AGCCGAGCTG 
GAACGTCGCC TCGCCATCCT GAAGGCATCC CAGCAGCAGC TGCAAGACAC GGAGAGCGCA 
CTCTCGGCCC ATCTTCAAGA ACTTACAAAT GCCTACAAGG ACGCAAACGT GTTTGAGAGA 
TTATTTCTGG ATGATCAGTT AAAAAATCTC AAAGCAAGGA CCAACAGAAC ACAGAGATTC 
CTTCAAAACA ACGGTAGCGA ACTCAAGCAG AAGATGGAGT CTTACAGAGA ATTCCATGAC 
AAAGCAGCAG TGCTTCAGAA AGAGGCTGAG TGCATCCTGC ATGGTGGACT TCTCCCGCTC 
CGTCAAGAGC TGGAGCAGGA TGCCAAAGAG CAGCTCGGCA ATCTTAGAGA CAAGCTGGCT 
GCTATTCGAG GCAGTCTCTC ACAAGTGTTG ACATCTGAAG AAGTGTTTGA CACTATAGGG 
CTAAGCTGGG ATGGTTCACT GCTAGCACGG TTACAAACCC AAGTGCTTGA AAGGGAGAGA 
GAAGTGGAAG GAAAAATTAA GCAGCTGGAC ACATTTTTAA TAGCACGGGA CAGACACCAG 
GCATCGATAA GTAAGATAAG GGCTGTGGAT CTGCAGATTA AGAAAGGGGC TGAATCACTA 
CTGAAAGTCC CCAGTATGTC ACCAGAAAGC ACTCTGCTCA ATGCACAAAC TTTGATTCAG 
AAAATTGAAA AATCCAAACG CTTGCGTGAT GAGATAATCA GGAAATTAAG CAAAAACGAG 
GCTTTTGACG ACTCGTTCAA AGAGAGCGAG ATGCAGCGAC TAAAGCTATG TGCAGAAGAG 
AATTCTAGGC TTCAAGAGGC TCTCCAGAAC ATGCTGCTAG AATTGCAACC AAGAGAAATG 
GGCGAAAAGG AATTCCGAGA GAAGCTAGAA AACGCCCTAC ATGTTTTAAA GCAAATACAG 
TCTCGGTTAC AGCAGCCTTT ATGTGTAAAT TTGGGGGTTC AACATATTCA ACACGAGAAG 
GAGACCTGGG AAGCATTTGG CGAGCAAGTC GAGGCAGAAA TGTGTGGTCT TAGAGCCGTG 
AGGATTACCG AAGAGCAAAG AGAAGAAAAC GATTCTGGAA CCGGTGGCAT GGAGGCAAAA 
TTACGGGACA TTGAAGGTCT TCACATGGAG CTTAGCAAAA GCATTAGTCT ACGTGCAGAT 
GTCCTGAACG ATGCTTATGA CAGTGCAAAC CGCTATGACG AGTTAGTAGC TGGGGCATTG 
AGAATCATCA CGTCCCTGGA AGCCACGCTT TTGTCGTACA GAGTAGACCT TCACAATCCC 
CAAAAGACAC TGGAGCTGGC ACACCTTAAA CAAGAGGAAC TGCAATCCTC CGTAGCTGAT 
TTACGGAGCC TCACCGAGAC TTTGGGGGCT ATCTCCAGCC CTGAGGCCAA AGAGCAACTT 
CGTTGTACTT TAGAAGTTCT AGCAGCTAAG AATTCAGCCT TGAAGGCAGG GCTGGAAGCC 
CAGGAGGCCG AGGAGGAAAG GTGCCTGGAG AATTACAAAT GCTTTAGAAA AATGAAAGAA 
GAAATTTGCT CTCGGCTCAG GAAAATGGAG ATGGATCTCG GACAGTCCAT ATTCCCGTTG 
CCCAGGTCTT ACAAAGAAGC CTTAGCGCGC CTGGAACAGA GCAAGGCGCT AACATCAAAT 
CTCCTGTCAA CCAAAGAAGA CTTAGTGAAA CTCCGTCAGC TCCTCAGACA CCTGAGATGC 
AGGAGCACAG AAAACGATGC CACATGCGCG CTTGGGGTGG CCTCCGCTCT GTGGGAGAAG 
TGGCTGAGTT TGCTGGAAGC CGCCAGAGAG TGGCAGCAGT GGGGTGGAGA GCTGAAGAGA 
GAGTGGAAGT TCATCAGTGA GGAGATTGAG CGAGAAGCAA TAATTTTAGA GACTCTTCAG 
GAGGACCTTC CAGAAATTTC CAAAACAAAC GCAGCTCCCA CCGAGGAACT CTGGCAGTTG 
TTGGACTCTC TGTGCCAGCA CCAGGAGAGT GTGGAGAAGC AGCAGCTGCT GCTGGCCCTG 
CTTCTACAGC GTGTCAGGAG TATCCAGAAC ATTCCCGAAG GCACCGAGAC CGGGGAAACC 
ATCCCGGCAC TTCAGGAGAT TGGGTCTATG CAAGAACGGT GCGACAGGCT TCTTCACACA 
ACTCGAAAGA ATAAGGACCT GGTCCAGGCC GAAATCCAGG CACAGCAGTC TTTCCTAAAG 
GAAATAAAGG ATGTGAAGCG TGTATTTGAA CAAATCTCAA CTTCTTTCCC AAACTTGGCA 
CCGGAAGGCC ACCCAGAACG GGCAGAACAG TTTGAGGAGC TGCGGAGCAT TCTTCAGAAA 
GGCAAGCTGA GTTTCGAGAA CATTATGGAA AAACTGCGCA TCAAGTATTC CGAGATGTAC 
AGCATAGTCC CTGCGGAGAT CGGATCCCAG GTGGAAGAAT GCAGGAGTGC CCTAGAGGAT 
GCTGAGGAGA AGATGAGCAG TGAAGTCTCA AAGAGCTCAC CATCAAGCAT CATGAGGAGG 
AAAATAGAGA GGATTAACAA CGGGCTCCAT TGTGTTGAAA AAATGCTGCA ACAGAAAAGC 
AGAAACATTG AGGAAGCTCA CGAAATCCAA AAGAAAATAT GGGATGAGCT CGACCTCTGG 
CATTCCAAGC TGAACGAGCT GGACTCTGAA GTTCAGGACT TCGTCGAGCA GGACCCAGGA 
CAGGCGCAAG AATGGATGGA CAACTTGATG GCTCCTTTCC AGCAACATCA ACAAGTATCC 
CAGAGAGCAG AATCCAGAAC CTCGCAGCTC AACAAGGCCA CGATCAAGAT GGAAGAATAC 
AATGATCTTC TGAAGAGTAC AGAGGTGTGG ATAGAAAAGA CCAGTTGTTT GCTGGCCAAC 
CCTGCCTGCT ATGACTCTTC AAGGACCCTT AGCCACCGCG CCAGCACCCT CCAGATGGCT 
CTGGAAGATT CTGAGCAGAA ACACAGCCTT CTACATTCAA TTTTCACGGA TCTAGAAGAC 
CTGTCAATCA TTTTTGAAAC AGATGACTTA ATCCAGACCA TTCACGAGTT AAGTGACCAG 
GTGGCCGCTT TACAGCAACA GATAATGGAG GCCCTCCCAC ACGTCCAGCA GGTGGCAGAT 
GATGTGGTTG CGATCGAGTC TGAAGTAAAA GCAATGGAGA AAAAGGTTGC AAAGATCAAA 
GCTATCCTCT TATCCAAAGA AATATTTGAT TTTCCACCTG AAGAACATCT CAAGCATGGG 
GAGGTCATAC TTGAAAACAT CCATCCCATG AAAAAGACTA TTGCTGAGAT AATGACTTAC 
CAAGTGGAAC TGAGGCTGCC CCAGACGGGA ACCAAGCCCC TGCCTGTGTT TCAGAGGACA 
AGCCAGCTTT TACAAGATGT GAAACTCTTG GAAAATGTGA CTCAGGAACA AAATGAGTTA 
CTGAAGGTTG TCATAAAGCA GACTGCTGAA TGTGATGAAG AAATAGACAG TCTGAAGCAG 
ATGTTAACTA ACTACTCAGC TGAGATCTCC CCTGAACATG TGTCACAGAA CCAAGTGGCC 
GACCTGCCGT CGTTACAGGG AGAGATGGAA AGGTTGGAAA AGCAGATTCT GAATCTAAAC 
CAGAAGAAGG AGGATCTGCT AGTGGACTTG AAGACTGCTG TACTGAACCT TCATGAGCAC 
CTGAAACAAG AACAGCAAGA AGTAGGAGAC AAGCCCTCTG CAGGCGCCTC CGAGTGTACA 
GTGGCCGAGA GGGATGCTTC AGAAAGGAAG CTGAGCAGAA CAAACTCCAT GTCTTTCCTG 
CCAGTGGTCA AGGAGGAGGC CGAAGAAAGC TCCGTGAAGA GCGAAGATGG ACGTAGGAGA 
ACAGAGCCAC CGTCCGCATC CTGGTCTTTT CTGGGGAAAC ACAGCAAGGA CCTGGAAGGG 
GATGGGGCAT CCTCCTCCTC CTCAGCCACC ATCGTGCAGG ATGCAGATGG GAGAATTAGC 
ACCTGTGACA GCTCCATGGT GCATATCATT GCCCCAGACT CGGGAAGCAC CGAGGAAGGA 
CCAGCACCAT CCCCGAGGCT CAGCCAAACA GACGAGGGTG CCACACCCCC CATTGAAGCT 
GCACTCCTGG ACTTTCCTAG AGAACAAGGA GCTTTTGAGT CCACCGTGGA GAGAAGTAGG 
CCTCGGCCTG CAGACATCCT CCGTGTCTGC AAGACCCAAG TGGCCAAGCT GGAGCTGTGG 
CTGCAACAAG CCAACGTGGC CTTTGAGCCA GAAACTGTAG ACGCGGACAT GCAACAGGTG 
GTGGAAGAGG AGCTGGCGGG GTGCCAGGCT ATGCTGACAG AGATTGAGTA CAAGGTCGCC 
TCTCTGCTAG AGACGTGCAA AGACCAGGGC CTGGGAGACT GTGGGACCAC TCAGCAGGAG 
GCCGAGGCCC TTTCCTGGAA ACTCAAGACT GTGAAGTGCA ACTTGGAAAA GGTCCAGATG 
GTGCTTCAGG AGAAGTTCAG TGAGGACCAG CATCCCTCCA CTCTTAAGAA ACCGTCAGAG 
CCCCACGACG TCGACCAGCC AGCTGGCCTT TCTGAGCTTG ACTCTGTCCT AACTGAAAGG 
CCACAGTTCA GCAGACAGAA GGATGCTCCC CAGCCACAGA TTCTGGAGTT AAAACCATCA 
GAGCAGAAAG ATTTAATCAA GTTCACAGAA CTGAATGCCA AGAAAACATG GCTGCAGGGT 
CACCAAGAGA ATGAAGATGC AAATCGGCAA TCAGCTTCCA GCAGCAAGGT CCCTAGTCCT 
GGGAATGCAG CATCAGATTC AACCTTGCCA CTTCAGGCCC AGAGCGGTGA CAAGTGGCAG 
TATCTTCACC ATGAACTAAC ATCAAGACCA AATCCCTCCG TACCTCAGCT TGTGGAGCCT 
CAGGTGGCCC TAACTACAAG TACTCTGCCC AGTGTGAGCG TGTATAACTT TAGATGCCCT 
ACAGCTGACG AACTGCAAGC TTACACCACC CAACTTGAAG AGCTACGCCA AGAAGCAAAC 
ACTATTCAGA CACAGGGAAG TATGACGGAA GAGACGTATA TCAGTTTGGA TAAAAGATTA 
TTTGAACTCT TTCTGAGCCT CAGTCGGTGC CTGGGCAGTG TGGAGGGGCT GCTGCAGAGA 
CCTGGGTTAC TCAGAGAGGA TGCATGTGCC CAGCAGGTGT TCTTCCAGAA ACTGGCTCTT 
GAGCTGAAGA AACTTTATTT AGCTCTGGGT GACAAGAAGG ATGATTTTCT GAAAGCTGTG 
ACTTGGCCTG GCAAGGAAGC CACGTTGCTA CCAGAATGTA TTGATGCTCT GACAGTCAGC 
CTGGAGAGTG TGCAGAGCAG AGCTGCCTGG AGGGACGCAT CCCTGAAGGC CGGCCTTGAG 
CACAGCCGCA GCTACCAGAA TGAAGTAAAG CGATTATACA GCCAACTCAT CAAGAAGAAG 
ACGGCTTTGC AACAGTCTTT GAACGAAATC AGTGGGCAGA GTATTAGCAA ACAGCTTCAG 
AAAGCAGATG TGCATACAGC AGAGCTGCAG AACTCTGAGA AGCAAGTCGC CAAACTGAGA 
GACGAAGGGG AGAGGCTCCG TTTCCCTCAT GGTTTACTCC AGGACGTCTA CAAGTTGGAG 
GATGTTCTTG ACAGTATGTG GGGAATCCTG AGAGCCAGAT ACTTAGAACT CAGCAGCCCC 
TTCCTCTCCA AGAGCCTGCA GACCTTGCTT CAAGGCATGG CGGAGCTAGT CAGTATTGGA 
AAAGGAAAGC TGGCCGCTGA CCCTTTGCAA CACGCCAAGA GCAAAGCTGC TTTGCAGGCC 
CAGTTACAAG ATCACAAGGC GTTTTTCCAG AAGCTTGTGG CCGACATGTT GTTGATTCAA 
ACCTATTCGG CAACAATGTT TCCACCTTCG TTACAAAAGG GAGAGGGATT TGGAGCAGAG 
CAAGTTGCGG AAGTGAGAGC CCTGGAGGAA GAGGCCTGCC TGCGTGGTGC GCAGCTTCAG 
AGCATGCTAC AGAAATGGGA AGAATTTGAT GATAACTATG CATCCCTTGA GAAGGACCTG 
GAAGCTCTCA TCTCTTCGCT GCCCTCCGTG AGTTTGGTGG AAGAGACGGA GGAGAGATTG 
CTGGAAAGGA TTTCATTTTA CCAGCAAATA AAAAGAAACA TTGATGGGAA GCATGCCCGG 
CTTTGCCAAA CCTTGAATGA AGGCAGACAG CTGGCAGCAT CTGTGAGCTG TCCTGAGCCA 
GAGGGCCAGA TCGCGAGGCT GGAAGAGCAA TGGCTGTCCC TCAACAAGAG AATCGACCAG 
GAGCTCCACC GACTGCAAAC CCTTCTTAAG CACCTTCTCA GTTACAGCAG AGATTCAGAT 
GAGCTAACCC GGTGGCTGGA GACTTCTCAG CAAACGTTGA ATTACTGGAA AGAACAATCC 
CTCAACGTGT CCCAGGACCT GAATACAATC AGAAGCAACA TAGACAGATT TTTTAAATTT 
TCCAAGGAAG TCGATGAGAG GTCCTCCCTG AAGTCCGCAG TCATGAGTAC TGGGAACCAA 
CTTCTCCACC TGAAAGAGGC AGACACGGCC ACACTGAGAG CCTCTTTAGC ACAATTTGAA 
CAGAAGTGGA CAGTGCTCAT AACTCAGCTT CCAGACATAC AAGAGAAACT TCACCAGCTT 
CAGATGGAGA AATTGCCGTC CCGAGAAGCA ATCTCCGAGA TGATCAGCTG GATGAACGCC 
GTGGAGCCTC AGGCGGCGGG CAAGGATACC GAGCTCTCAA AGAGTTCTGC GTCTCAGGTG 
AAACATCTTC TGCAGAAGCT CAAGGAGTTC AGGATGGAAA TGGACTACAA GCAATGGGTA 
GTTGACTTTG TTAACCAGTC GCTGCTCCAG CTAAGCACCT GTGACGTAGA AAGCAAGCGC 
TATGAAAGGA CGGAGTTTGC TGAGCACCTC GGGGAGATGA ACCGCCAGTG GCAGCGAGTG 
CACGGAACCC TGAATAGAAA GATACAACAT TTGGAACAAC TTTTGGAAAG TATCACTGAG 
AATGAAAACA AAGTACAGAA TTTGAACAGC TGGTTGGAGG CACAGGAAGA AAGGCTGAAG 
ATGCTACAAA AACCCGAAAG TGCCGTCTCC ATGGAGAAGC TGTTACTGGA CTGCCAGGAT 
ATAGAAAACC AGCTTGCCCT GAAATCTAAA GCTCTGGACG AGTTGAGACA AAGTTCTCTG 
ACAATGGATG GGGGAGACGT GCCATTGTTA GAAGACATGG CATCTGGAAT TGTTGAGCTG 
TTTCAAAAGA AGAATAACGT GACCAGCCAG GTCCACCAGC TCAGAGCTTC TGTGCAATCA 
GTACTACAGG AGTGGAAGGC CTGTGACAAG CTCTATGATG AGGCCACCAT GAGGACAACC 
CAACTCACAT ATTCCATGGA GCACAGCAAG CCTGCGGTCT TATCGTTGCA GGCCTTGGCC 
TGCCAGGTGC AGAACCTTGA GGCCCTTCAG GATGAAGCTG AGAACGGGGA ACGGAGCTGG 
GAGAAACTGC AGGAGGTCAT TGGCAGACTC AAAGCTTCCT GCCCCTCCAT GGCTGGCATA 
ATCGAAGAGA AATGCCAGGA TGCTCATTCG AGGTGGACCC AAGTGAACCA AGACCTCGCA 
GACCAGTTGC AGGAGGCCCG AGGGCAGCTG CAGCTCTGGA AGGCTCCTCA CAATGCTCAC 
GCAGAAGCGG CAGCCTGGCT GCAGCAGCAG GAAGCAAAGT TCCAACAGCT TGCCAACACC 
AATCTGTCTG GAGACAACCT GGCAGATATC CTGCCACGGG CCCTGAAGGA CATAAAGGGG 
CTGCAGAGTG ACCTGCAGAA GACCAAAGAG GCCTTCCTGG AAAATTCTAC CCTCTCGGAT 
CAGCTGCCAC AGCCTGAGGA GCGCAGCACC CCTGGGCTCC ATTCTGGACA GCGGCACTCC 
CTCCAGACAG CTGCCTATTT AGAAAAGATG CTGCTGGCAA AATCAAATGA ATTTGAGATT 
GTTCTGGCAC AGTTTAAGGA TTTTACAGAC CGGCTGGCAT ATTCAAAAGA CCTTATTGTG 
CACAAGGAAG AAAATCTGAA TAAACTTTAC CATGAAGAGA AAGAAGAAGT TCCTGACTTG 
TTCCTGAACC ACGTGCTGGC CCTGACAGCC CAGTCACCTG ACATTGAACG TTTGAATGAA 
GAGAGCCTCA GGCTTCCCCT CAGTGACGTA ACAATAAAAA CATTACAAAG CTTGAACCGG 
CAGTGGATCC GGGCTACGGC CACAGCGCTG GACCACTACA GCGAACTTCA GGGAAATGGG 
TTGAATGAAA AGTTCCTTCA TTACTGTGAA AGATGGATCC AAGTTCTGGA GAAGATCCAA 
GAATCACTTT CAGTGGAGGT TGCCCACAGC CTCCCTGCTC TACTGGAGCA ACAGAAAACC 
TACGAGATAT TAGAAGCTGA AGTCTCTACA AACCAGGCAG TCGCTGACGC TTATGTGACC 
CAGTCCTTAC AACTCCTGGA CACAGCAGAA ATAGAAAAGA GACCAGAATT TGTCTCTGAA 
TTCTCCAAGC TGTCAGACCA ATGGCAGAGG GCCGCCCGGG GTGTTCGGCA GAGGAAGTGT 
GACATCAGCA GGCTGGTGAC ACAGTGGCGG TTCTTTACCA CCTCTGTGGA GGACTTGCTG 
CGGTTCCTCG CCGACACCAG CCAACTACTG TCTGCAGTGA AGGAGCAGGA CTGTTACAGC 
CTCTGCCAAA CCAGGCGCCT GGTCCACGAG CTGAAGAGCA AAGAGATCCA TCTTCAGAGG 
TGGCGAACAA CGTACGCACT GGCCTTGGAA GCCGGGGAGA AGTTGCGGAA CACACCCAGC 
CCAGAAACGA GAGAATTCGT AGACGGACAA ATCAGCAGGC TTCAGGAAAG CTGGAAGGAC 
ACTGAGCTTA GCCTGGGAGA GGTGATCAGC CGGCTCCAGA GCACTGCAGA GACCTGGGAC 
CAATGTAAAA AGAAAATCAA GAAGCTGAAA AAGAGGCTGC AGGCTCTGAA GGCACAAAGC 
GAAGATCCCC TTCCTGAGCT TCACGAGGCC CTCCATGAAG AAAAGGAGCT GATTAAGGAA 
GTAGAGAAGT CTCTGGCTAA CTGGACGCAC AGCTTGAAAG AACTTCAGAC TATGAAGGCC 
GACTTGAGCC AGCACATCCT GGCGGAGGAC GTGACGGTTC TGAAGGAGCA GATCCAGCTT 
TTGCACAGAC AATGGGAGGA CCTCTGCCTA AGAGTGGCTA TCCGCAAGCA GGAGATTGAA 
GACAGACTCA ATTCGTGGAT CGTGTTCAAT GAGAAAAATA AAGAACTGTG TGCTTGGCTG 
GTCCAGATGG AAAACAAAGT TCTACAGACA GCAGATGTCA GCATTGAAGA AATGATCGAA 
AAGCTACAGA AAGACTGTAT GGAAGAAATC AGCTTATTCA CAGAAAACAA ACTGCAGCTG 
AAGCAGATGG GCGACCAGCT GATCAAGGCC AGCAGCAAGG CCAAGGCGGC TGAGCTGGAG 
GAGAAGCTCA GCAAGATCAA CGACCGCTGG CAGCATCTCT TTGACGTCAT CGGATCAAGG 
GTGAAGAAGC TGAAGGAGAC GTTTGCTTTC ATTCAGCAGT TAGACAAAAA CATGAGCAAC 
CTTCGTACCT GGTTGGCTCG CATTGAGTCT GAGCTCTCCA AGCCTGTTGT CTACGACGTC 
TGCGATAACC AGGAGATCCA GAAGAGGCTT GCTGAGCAGC AGGATCTGCA GCGAGATATC 
GAACAACACA GTGCAGGGGT GGAGTCTGTG TTTAATATCT GTGACGTCCT TCTGCATGAC 
TCTGATGCCT GTGCCAATGA AACGGAGTGT GACTCAATCC AGCAGACCAC CAGGAGCCTG 
GACAGGCGCT GGAGGAACAT TTGTGCCATG TCAATGGAGC GACGCATGAA AATCGAGGAG 
ACCTGGCGGC TTTGGCAGAA ATTTTTAGAT GACTATTCTC GCTTCGAGGA CTGGCTCAAG 
TCGGCCGAGA GGACAGCGGC CTGCCCTAAT TCCTCCGAGG TGTTGTATAC AAATGCCAAA 
GAGGAGCTGA AACGGTTTGA GGCCTTTCAG CGGCAGATTC ACGAACGACT GACACAGCTG 
GAGCTCATCA ACAAGCAGTA CCGGCGGCTG GCTCGAGAGA ACCGCACCGA CACAGCCAGC 
AAGCTGAAGC AGATGGTGCA CGAGGGCAAC CAGCGCTGGG ACAATCTGCA GAAGCGGGTC 
ACAGCCATCC TGCGGAGACT CAGGTACTTC ACCAACCAGA GGGAAGAGTT TGAGGGCACC 
AGGGAGAGCA TTCTGGTTTG GCTCACAGAA ATGGACCTGC AGCTGACCAA CGTAGAACAC 
TTCTCAGAGA GTGACGCTGA GGACAAGATG CGCCAACTGA ACGGCTTCCA ACAGGAGATC 
ACACTGAACA CCAACAAGAT CGACCAGCTC ATCGTGTTTG GGGAGCAGCT CATTCAGAAG 
AGTGAGCCCC TCGACGCCGT CCTGATCGAG GACGAGCTAG AGGAGCTGCA CCGCTACTGT 
CAGGAGGTGT TCGGCAGAGT GTCTCGCTTC CACCGCCGCC TGACCTCCCA CACCCCGGGC 
TTAGATGATG AGAAGGAGGC GTCTGAGAAT GAGACGGACA TAGAAGACCC CAGGGAGATC 
CAGGCTGACT CTTGGCGTAA GAGGAGAGAG AGCGAGGAGC CCACATCTCC CCAGTCACTG 
TGTCACCTTG TGCCTCCGGC TCTGGGACAT GAGCGGTCTG GCTGTGAGAC CCCCGTCAGT 
GTGGACTCTA TCCCTCTGGA GTGGGATCAC ACAGGTGACG TGGGGGGATC CTCTTCTCAT 
GAAGACGACG AGGAGGGCCC ATTCTACAGC GCACTGTCAG GTAAATCCAT TTCTGAGGGC 
CACCCGTGGC ATGTTCCTGA CAGCCCTTCC CATTCCAAGC ATCACTACAA ACACATGGAA 
GGTGACAGGA CTGAGGCACC AGTCCCCACA GATGCCAGCA CGCCTTTCAA ATCAGACTAT 
GTAAAGCTGC TATTACGTCA AGGCACCGAT GACAGCAAAG AAGGCTTAAA GGAGGCTCAG 
CAGGAAGATG AGCAGCTGGC CACTTTAACG GGACAGCAGC CAGGTGCCTT CGACAGGTGG 
GAGCTGATCC AGGCGCAGGA GCTTCACAGC AAGCTCAGGC TCAAACAGAC CGTGCAGCAG 
CTCAAGTCTG ACATCGGCAG CATCGCTGCT TGGCTTGGGA AAACTGAGGC CGAGCTGGAA 
GCTCTGAAGT TGGCCGAGCC TCCCTCTGAC ATCCAGGAAA TAGCGCTCAG GGTGAAGAGA 
CTGCAAGAGA TACTAAAAGC CTTCGATACC TACAAGGCCT TGATGGTCTC CGTCAATGTG 
AGCCACAAGG AATATCTGCC AAGCCAGAGC CCCGAAGCCA CAGAACTCCA AAATAGACTC 
CATCAGCTGA GCCTGTCCTG GGACTCGGTC CAGGGCGTAT TGGACAGCTG GCGAGGAGAC 
TTACGGCAGT CACTCATGCA GTGCCAGGAC TTTCACCAGC TGAGTCAAGA CTTGCTCCTG 
TGGCTAGCGA CAGCAGAGAG CCGCAGGCAG AAGGCGCATG TCACCAGCCC AGAGGCCGAC 
CGCCAGGTCC TCCTGGAGTG TCAGAAAGAC CTAATGCGCC TAGAAAAGGA GTTGGTAGCC 
CGTCAGCCTC AAGTCAGCTC CTTGCGGGAG ATTTCCTCCA GCCTTCTGGT GAAGGGGCAA 
GGAGAAGACT ACATTGAGGC CGAAGAGAAG GTCCACGTGA TCGAGAAGAA ACTCAAGCAA 
CTGCAAGAGC AAGTGGCTCA AGATCTGATG TCCTTGCAGA GAAGCCTGGA TCCGGATGCT 
TCTCTAACCA GCTTTGATGA GGTGGACTCA GGAGAACAGC TCCCAGCAGC CTTTGCAAAG 
AGTCCAAGGC CCCGCTGGAC CTTCTTGGAA GAGGAAGAGG AGGAGGAGGA GACAGACAGC 
AGGATGCCCC ACCTCGACAG CCCCGGCAGC TCCCAGCCGA GACGCTCCTT CCTCTCAAGG 
GTGATCAGGG CAGCGCTACC GTTGCAGCTG CTTCTGCTGC TGCTGCTGCT CCTGGCCTGC 
CTGCTACCTG CCTCTGAAGA TGACTACAGC TGCACCCAGG CCAACAACTT TGCCCGATCC 
TTCTACCCCA TGCTGCGGTA CACCAACGGG CCACCTCCCA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

p63 Transcription Factor Regulates Nuclear?Shape and Expression of Nuclear?Envelope-Associated Genes in Epidermal Keratinocytes.
The Journal of investigative dermatology137(10)2157-2167(2017 Oct)
Rapisarda V,Malashchuk I,Asamaowei IE,Poterlowicz K,Fessing MY,Sharov AA,Karakesisoglou I,Botchkarev VA,Mardaryev A

Nesprin 1?2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.
The Journal of cell biology216(7)1915-1924(2017 Jul)
Stroud MJ,Feng W,Zhang J,Veevers J,Fang X,Gerace L,Chen J

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Syne2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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