Itga11 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itga11
Entrez Gene ID	319480
Full Name	integrin alpha 11
Synonyms	4732459H24Rik
General protein information	Preferred Names integrin alpha 11 Names integrin alpha-11 integrin a11
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 B

mRNA and Protein(s)

mRNA	Protein	Name
NM_176922.5	NP_795896.4	integrin alpha-11 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	ITGA11	NP_001004439.1
Rattus norvegicus (Norway rat)	Itga11	NP_001101626.1
Gallus gallus (chicken)	ITGA11	XP_004943980.1
Danio rerio (zebrafish)	itga11a	NP_001166098.1
Pan troglodytes (chimpanzee)	ITGA11	XP_510503.3
	ITGA11	XP_001083531.2
Canis lupus familiaris (dog)	ITGA11	XP_005638763.1
Mus musculus (house mouse)	Itga11	NP_795896.4
Danio rerio (zebrafish)	itga11b	XP_695559.5
Xenopus tropicalis (tropical clawed frog)	itga11	XP_002932992.1
Bos taurus (cattle)	ITGA11	XP_002690571.2

Gene Ontology
Bibliography

Related articles in PubMed

Overexpression of integrin ?11 induces cardiac fibrosis in mice.
Romaine A, S?rensen IW, Zeltz C, Lu N, Erusappan PM, Melleby AO, Zhang L, Bendiksen B, Robinson EL, Aronsen JM, Herum KM, Danielsen HE, Sjaastad I, Christensen G, Gullberg D
Acta physiologica (Oxford, England)(2017 Aug)

The ?11 integrin mediates fibroblast-extracellular matrix-cardiomyocyte interactions in health and disease.
Civitarese RA, Talior-Volodarsky I, Desjardins JF, Kabir G, Switzer J, Mitchell M, Kapus A, McCulloch CA, Gullberg D, Connelly KA
American journal of physiology. Heart and circulatory physiology311(1)H96-H106(2016 Jul)

Stromal Integrin ?11?1 Affects RM11 Prostate and 4T1 Breast Xenograft Tumors Differently.
Reigstad I, Smeland HY, Skogstrand T, Sortland K, Schmid MC, Reed RK, Stuhr L
PloS one11(3)e0151663(2016)

Mmu-miR-126a-3p plays a role in murine embryo implantation by regulating Itga11.
Li Z, Jia J, Gou J, Tong A, Liu X, Zhao X, Yi T
Reproductive biomedicine online31(3)384-93(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Deletion of ITGA11 in diabetic mice attenuates cardiac fibrosis progression but does not improve cardiac function. Impairments of cardiac function in null mice appear to be due to a novel role of ITGA11 in regulating cardiomyocyte growth and organization and myofibril development.
Title: The ?11 integrin mediates fibroblast-extracellular matrix-cardiomyocyte interactions in health and disease.

In NSCLC xenografts in Itga11-knockout mice, collagen cross-linking is associated with stromal alpha11 expression. Loss of tumor stromal alpha11 expression was correlated with decreased collagen reorganization and stiffness.
Title: Integrin ?11?1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer.

Deficiency of stromal integrin alpha11beta1 showed different effects on tumor growth and collagen fibril diameter depending on tumor type, but no effect on tumor interstitial fluid pressure or development of lung metastasis.
Title: Stromal Integrin ?11?1 Affects RM11 Prostate and 4T1 Breast Xenograft Tumors Differently.

miR-126a-3p may play a major role in embryo implantation by regulating Itga11, possibly through impairing cell migratory and invasive capacity.
Title: Mmu-miR-126a-3p plays a role in murine embryo implantation by regulating Itga11.

Dermal fibroblasts lacking alpha11beta1 are unable to efficiently convert to myofibroblasts, resulting in scar tissue with compromised tensile strength.
Title: Reduced granulation tissue and wound strength in the absence of ?11?1 integrin.

The following Itga11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itga11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu05751	NM_176922.5 Latest version!	Mus musculus integrin alpha 11 (Itga11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$699.30 $999.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itga11 ( NM_176922.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_795896.4 Mus musculus integrin alpha 11 (Itga11), mRNA.

Price & Availability↑

CloneID	OMu05751
Clone ID Related Accession (Same CDS sequence)	NM_176922.5
Accession Version	NM_176922.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	integrin alpha-11 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB840351.1, AY124460.1, AK028821.1 and BB731359.1. On Mar 27, 2009 this sequence version replaced NM_176922.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058716.1, AY124460.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGGACTTTC CCAGGGGCCT CCTGGTGGCC TGGACCCTCA GCCTTTGGCC AGGATTCACG 
GACACCTTCA ATATGGATAC CAGAAATCCC CGGGTCATTG CTGGTCCCAG TGCTGCCTTC 
TTTGGCTACA CAGTACAGCA GCATGATATC AGTGGCAAGA AGTGGTTGGT TGTGGGTGCC 
CCAATGGAAA CCAATGGCCA TCAGAAGACA GGAGACGTAT ACAAATGTCC GGTAACCCAG 
GGCAACTGCA CCAAGCTCAA CCTGGGCAGG GTCACTCTGT CCAATGTGTC TGAGAGGAAG 
GACAACATGC GCCTCGGCCT GAGCCTTGCC ACCAACCCCA AGGACAACAG CTTCCTGGCC 
TGCAGCCCTC TCTGGTCGCA CGAGTGTGGA AGCTCCTACT ACACCACTGG CATGTGCTCA 
CGGGTCAACT CCAACTTCAG ATTCTCTAAG ACGGTAGCTC CGGCACTTCA GAGGTGCCAG 
ACTTACATGG ACATCGTCAT TGTCTTAGAT GGCTCCAACA GCATCTACCC CTGGGTGGAG 
GTCCAACACT TCCTCATCAA TATCCTCAAA AAGTTCTACA TTGGCCCCGG CCAGATCCAG 
GTCGGAATAG TCCAGTATGG AGAAGATGCC GTCCATGAGT TCCACCTTAA TGACTACAGG 
TCTGTAAAAG ATGTGGTGGA AGCCGCCAGC CACATTGAGC AGAGAGGAGG GACAGAGACC 
CGCACGGCAT TTGGCATTGA ATTTGCACGC TCGGAGGCTT TCCAGAAGGG TGGAAGAAAA 
GGGGCCAAGA AAGTGATGAT TGTCATCACG GACGGGGAAT CCCACGACAG CCCAGACCTG 
GAGAAGGTGA TCCGGCAGAG CGAGAAGGAC AACGTGACCA GATACGCTGT GGCCGTTTTG 
GGCTACTACA ACCGCAGGGG GATCAATCCA GAGACTTTTC TAAATGAAAT CAAATACATC 
GCCAGCGACC CTGACGACAA GCACTTCTTC AACGTCACAG ATGAGGCGGC CCTGAAGGAC 
ATTGTTGATG CCCTTGGGGA CAGGATCTTC AGCTTGGAAG GCACCAACAA GAATGAGACC 
TCTTTTGGGC TGGAGATGTC GCAGACTGGC TTTTCTTCAC ATGTGGTAGA GGATGGGATC 
CTGCTGGGAG CTGTGGGAGC CTATGACTGG AACGGGGCGG TGCTGAAGGA GACAAGTGCT 
GGCAAGGTGA TTCCTCACCG AGAGTCCTAC CTTAAGGAGT TTCCAGAGGA GCTGAAGAAC 
CATGCAGCAT ACCTAGGGTA CACGGTGACG TCGGTTGTGT CCTCCAGGCA GGGGCGGGTG 
TATGTGGCTG GAGCCCCCAG ATTCAACCAT ACTGGCAAGG TCATTCTATT CAGCATGCAC 
AACAACCGGA GCCTCACCAT CCACCAGGCT CTTCGGGGCG AGCAGATAGG CTCCTACTTT 
GGGAGTGAGA TTACCTCAGT GGACGTCAAT GATGACAGAG TGACAGATGT GCTGCTGGTG 
GGTGCACCCA TGTACTTCAG CGAGGGCCGA GAGCGAGGCA AGGTGTATGT CTACAACCTG 
AGACAGAACC GGTTTGTTTA TAATGGCACT CTGAAGGATT CCCACAGCTA CCAGAACGCC 
CGGTTCGGGT CCTGCATCGC CTCTGTTCAA GACCTCAACC AAGATTCCTA CAATGATGTG 
GTGGTGGGGG CCCCTCTGGA GGACAGCCAC AGAGGGGCCA TCTACATCTT CCATGGCTTC 
CAAACCAATA TCCTGAAGAA GCCCATGCAG AGAATAACAG CCTCGGAGCT GGCTCCTGGC 
CTGCAGCATT TTGGCTGCAG CATCCACGGA CAACTGGACC TCAATGAGGA TGGGCTTGTG 
GACCTAGCAG TGGGCGCCCT GGGCAACGCT GTGGTTTTGT GGGCCCGCCC TGTAGTTCAA 
ATCAACGCCA GCCTCCACTT TGAGCCTTCC AAGATCAACA TCTTCCACAA GGACTGCAAG 
CGCAATGGCA GGGATGCCAC CTGCCTGGCC GCCTTCCTCT GCTTCATACC CATCTTCCTG 
GCACCCCACT TCCAAACAGC AACCGTCGGC ATCAGGTACA ATGCAACCAT GGATGAGAGG 
CGGTATATGC CGCGGGCACA TCTGGACGAG GGCGGAGACC AGTTCACCAA CAGAGCCGTC 
CTGCTCTCCT CTGGCCAGGA ACACTGTCAA AGGATCAACT TCCATGTCCT GGACACTGCA 
GACTACGTGA AGCCAGTGGC CTTCTCCGTG GAGTACTCCC TAGAGGACCC TGACAACGGC 
CCCATGCTGG ACAACGGCTG GCCCACTACG CTCAGAGTGT CGGTGCCCTT CTGGAATGGC 
TGTAATGAGG ATGAACACTG TGTCCCTGAC CTTGTACTGG ATGCTCGGAG TGACCTGCCC 
ACTGCCATGG AGTACTGCCA GCGGGTGCTG GGGAGGCCGG CGCAGGACTG CTCCAGCTAC 
ACCCTGTCCT TCGACACCAC TGTCTTCATC ATAGAGAGCA CGCGCCGCCG GGTGGCAGTG 
GAGGCCACGC TGGAGAACAG AGGAGAGAAT GCTTACAGCG CCGTCCTCAA CATCTCCCAG 
TCAGAGAACC TTCAGTTTGC CAGCCTGATC CAGAAGGATG ACTCAGACAA CAGCATCGAG 
TGTGTGAACG AGGAGAGGCG GCTTCACAAG AAAGTCTGCA ACGTCAGCTA CCCCTTCTTC 
AGAGCCAAGG CCAAGGTGGC TTTCCGTCTG GATTTCGAGT TCAGCAAGTC TGTGTTTCTG 
CACCATCTTC AGATCCATCT GGGTGCCGGC AGTGACAGTC ACGAGCAAGA CAGCACCGCA 
GACGATAACA CGGCCCTCCT GCGCTTCCAC CTCAAATATG AAGCAGACGT CCTCTTTACC 
AGAAGCAGCA GCCTGAGCCA CTTCGAGGTC AAGGCAAACA GCTCACTTGA GAGCTATGAT 
GGCATCGGAC CTCCGTTCAA CTGTGTTTTC AAGGTGCAGA ACCTGGGCTT TTTCCCCATC 
CACGGGGTGA TGATGAAGAT CACTGTGCCC ATCGCCACCA GGGGTGGCAA CCGCCTGCTG 
ATGTTGAGGG ACTTCTTCAC CGACCAGGGC AACACATCCT GTAACATCTG GGGGAACAGC 
ACAGAGTACA GGAGTACCCC AACTGAGGAA GATCTGAGCC ATGCCCCACA GAGGAATCAC 
AGCAACTCCG ACGTGGTCTC CATCATCTGC AACCTGAGGC TGGCCCCCAG CCAGGAGACC 
AGCTTCTACC TGGTGGGAAA CCTGTGGCTG ACATCTCTGA AAGCACTCAA GTACAGGTCT 
CTGAAGATCA CAGTCAACGC CGCCTTGCAG AGGCAGTTCC ACAGCCCCTT CATCTTCCGA 
GAGGAAGACC CTAGCCGCCA GGTCACATTT GAGATCTCCA AGCAAGAAGA CTGGCAGGTC 
CCCATCTGGA TCATCGTGGG CAGCACTCTG GGGGGCCTCT TGCTGCTGGC CCTGCTGGTC 
CTGGCACTGT GGAAGCTCGG TTTTTTTAAA AGTGCCAAGC GCAAGAGGGA ACCTGGCCTA 
GGCCCCATCC CCAAAGAGCT CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_795896.4
CDS	91..3657
Translation	MDFPRGLLVAWTLSLWPGFTDTFNMDTRNPRVIAGPSAAFFGYTVQQHDISGKKWLVVGAPMETNGHQKTGDVYKCPVTQGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVEVQHFLINILKKFYIGPGQIQVGIVQYGEDAVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHDSPDLEKVIRQSEKDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGILLGAVGAYDWNGAVLKETSAGKVIPHRESYLKEFPEELKNHAAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFSMHNNRSLTIHQALRGEQIGSYFGSEITSVDVNDDRVTDVLLVGAPMYFSEGRERGKVYVYNLRQNRFVYNGTLKDSHSYQNARFGSCIASVQDLNQDSYNDVVVGAPLEDSHRGAIYIFHGFQTNILKKPMQRITASELAPGLQHFGCSIHGQLDLNEDGLVDLAVGALGNAVVLWARPVVQINASLHFEPSKINIFHKDCKRNGRDATCLAAFLCFIPIFLAPHFQTATVGIRYNATMDERRYMPRAHLDEGGDQFTNRAVLLSSGQEHCQRINFHVLDTADYVKPVAFSVEYSLEDPDNGPMLDNGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLGRPAQDCSSYTLSFDTTVFIIESTRRRVAVEATLENRGENAYSAVLNISQSENLQFASLIQKDDSDNSIECVNEERRLHKKVCNVSYPFFRAKAKVAFRLDFEFSKSVFLHHLQIHLGAGSDSHEQDSTADDNTALLRFHLKYEADVLFTRSSSLSHFEVKANSSLESYDGIGPPFNCVFKVQNLGFFPIHGVMMKITVPIATRGGNRLLMLRDFFTDQGNTSCNIWGNSTEYRSTPTEEDLSHAPQRNHSNSDVVSIICNLRLAPSQETSFYLVGNLWLTSLKALKYRSLKITVNAALQRQFHSPFIFREEDPSRQVTFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFKSAKRKREPGLGPIPKELK

Target ORF information:

RefSeq Version	NM_176922.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus integrin alpha 11 (Itga11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176922.5

ORF Insert Sequence:

ATGGACTTTC CCAGGGGCCT CCTGGTGGCC TGGACCCTCA GCCTTTGGCC AGGATTCACG 
GACACCTTCA ATATGGATAC CAGAAATCCC CGGGTCATTG CTGGTCCCAG TGCTGCCTTC 
TTTGGCTACA CAGTACAGCA GCATGATATC AGTGGCAAGA AGTGGTTGGT TGTGGGTGCC 
CCAATGGAAA CCAATGGCCA TCAGAAGACA GGAGACGTAT ACAAATGTCC GGTAACCCAG 
GGCAACTGCA CCAAGCTCAA CCTGGGCAGG GTCACTCTGT CCAATGTGTC TGAGAGGAAG 
GACAACATGC GCCTCGGCCT GAGCCTTGCC ACCAACCCCA AGGACAACAG CTTCCTGGCC 
TGCAGCCCTC TCTGGTCGCA CGAGTGTGGA AGCTCCTACT ACACCACTGG CATGTGCTCA 
CGGGTCAACT CCAACTTCAG ATTCTCTAAG ACGGTAGCTC CGGCACTTCA GAGGTGCCAG 
ACTTACATGG ACATCGTCAT TGTCTTAGAT GGCTCCAACA GCATCTACCC CTGGGTGGAG 
GTCCAACACT TCCTCATCAA TATCCTCAAA AAGTTCTACA TTGGCCCCGG CCAGATCCAG 
GTCGGAATAG TCCAGTATGG AGAAGATGCC GTCCATGAGT TCCACCTTAA TGACTACAGG 
TCTGTAAAAG ATGTGGTGGA AGCCGCCAGC CACATTGAGC AGAGAGGAGG GACAGAGACC 
CGCACGGCAT TTGGCATTGA ATTTGCACGC TCGGAGGCTT TCCAGAAGGG TGGAAGAAAA 
GGGGCCAAGA AAGTGATGAT TGTCATCACG GACGGGGAAT CCCACGACAG CCCAGACCTG 
GAGAAGGTGA TCCGGCAGAG CGAGAAGGAC AACGTGACCA GATACGCTGT GGCCGTTTTG 
GGCTACTACA ACCGCAGGGG GATCAATCCA GAGACTTTTC TAAATGAAAT CAAATACATC 
GCCAGCGACC CTGACGACAA GCACTTCTTC AACGTCACAG ATGAGGCGGC CCTGAAGGAC 
ATTGTTGATG CCCTTGGGGA CAGGATCTTC AGCTTGGAAG GCACCAACAA GAATGAGACC 
TCTTTTGGGC TGGAGATGTC GCAGACTGGC TTTTCTTCAC ATGTGGTAGA GGATGGGATC 
CTGCTGGGAG CTGTGGGAGC CTATGACTGG AACGGGGCGG TGCTGAAGGA GACAAGTGCT 
GGCAAGGTGA TTCCTCACCG AGAGTCCTAC CTTAAGGAGT TTCCAGAGGA GCTGAAGAAC 
CATGCAGCAT ACCTAGGGTA CACGGTGACG TCGGTTGTGT CCTCCAGGCA GGGGCGGGTG 
TATGTGGCTG GAGCCCCCAG ATTCAACCAT ACTGGCAAGG TCATTCTATT CAGCATGCAC 
AACAACCGGA GCCTCACCAT CCACCAGGCT CTTCGGGGCG AGCAGATAGG CTCCTACTTT 
GGGAGTGAGA TTACCTCAGT GGACGTCAAT GATGACAGAG TGACAGATGT GCTGCTGGTG 
GGTGCACCCA TGTACTTCAG CGAGGGCCGA GAGCGAGGCA AGGTGTATGT CTACAACCTG 
AGACAGAACC GGTTTGTTTA TAATGGCACT CTGAAGGATT CCCACAGCTA CCAGAACGCC 
CGGTTCGGGT CCTGCATCGC CTCTGTTCAA GACCTCAACC AAGATTCCTA CAATGATGTG 
GTGGTGGGGG CCCCTCTGGA GGACAGCCAC AGAGGGGCCA TCTACATCTT CCATGGCTTC 
CAAACCAATA TCCTGAAGAA GCCCATGCAG AGAATAACAG CCTCGGAGCT GGCTCCTGGC 
CTGCAGCATT TTGGCTGCAG CATCCACGGA CAACTGGACC TCAATGAGGA TGGGCTTGTG 
GACCTAGCAG TGGGCGCCCT GGGCAACGCT GTGGTTTTGT GGGCCCGCCC TGTAGTTCAA 
ATCAACGCCA GCCTCCACTT TGAGCCTTCC AAGATCAACA TCTTCCACAA GGACTGCAAG 
CGCAATGGCA GGGATGCCAC CTGCCTGGCC GCCTTCCTCT GCTTCATACC CATCTTCCTG 
GCACCCCACT TCCAAACAGC AACCGTCGGC ATCAGGTACA ATGCAACCAT GGATGAGAGG 
CGGTATATGC CGCGGGCACA TCTGGACGAG GGCGGAGACC AGTTCACCAA CAGAGCCGTC 
CTGCTCTCCT CTGGCCAGGA ACACTGTCAA AGGATCAACT TCCATGTCCT GGACACTGCA 
GACTACGTGA AGCCAGTGGC CTTCTCCGTG GAGTACTCCC TAGAGGACCC TGACAACGGC 
CCCATGCTGG ACAACGGCTG GCCCACTACG CTCAGAGTGT CGGTGCCCTT CTGGAATGGC 
TGTAATGAGG ATGAACACTG TGTCCCTGAC CTTGTACTGG ATGCTCGGAG TGACCTGCCC 
ACTGCCATGG AGTACTGCCA GCGGGTGCTG GGGAGGCCGG CGCAGGACTG CTCCAGCTAC 
ACCCTGTCCT TCGACACCAC TGTCTTCATC ATAGAGAGCA CGCGCCGCCG GGTGGCAGTG 
GAGGCCACGC TGGAGAACAG AGGAGAGAAT GCTTACAGCG CCGTCCTCAA CATCTCCCAG 
TCAGAGAACC TTCAGTTTGC CAGCCTGATC CAGAAGGATG ACTCAGACAA CAGCATCGAG 
TGTGTGAACG AGGAGAGGCG GCTTCACAAG AAAGTCTGCA ACGTCAGCTA CCCCTTCTTC 
AGAGCCAAGG CCAAGGTGGC TTTCCGTCTG GATTTCGAGT TCAGCAAGTC TGTGTTTCTG 
CACCATCTTC AGATCCATCT GGGTGCCGGC AGTGACAGTC ACGAGCAAGA CAGCACCGCA 
GACGATAACA CGGCCCTCCT GCGCTTCCAC CTCAAATATG AAGCAGACGT CCTCTTTACC 
AGAAGCAGCA GCCTGAGCCA CTTCGAGGTC AAGGCAAACA GCTCACTTGA GAGCTATGAT 
GGCATCGGAC CTCCGTTCAA CTGTGTTTTC AAGGTGCAGA ACCTGGGCTT TTTCCCCATC 
CACGGGGTGA TGATGAAGAT CACTGTGCCC ATCGCCACCA GGGGTGGCAA CCGCCTGCTG 
ATGTTGAGGG ACTTCTTCAC CGACCAGGGC AACACATCCT GTAACATCTG GGGGAACAGC 
ACAGAGTACA GGAGTACCCC AACTGAGGAA GATCTGAGCC ATGCCCCACA GAGGAATCAC 
AGCAACTCCG ACGTGGTCTC CATCATCTGC AACCTGAGGC TGGCCCCCAG CCAGGAGACC 
AGCTTCTACC TGGTGGGAAA CCTGTGGCTG ACATCTCTGA AAGCACTCAA GTACAGGTCT 
CTGAAGATCA CAGTCAACGC CGCCTTGCAG AGGCAGTTCC ACAGCCCCTT CATCTTCCGA 
GAGGAAGACC CTAGCCGCCA GGTCACATTT GAGATCTCCA AGCAAGAAGA CTGGCAGGTC 
CCCATCTGGA TCATCGTGGG CAGCACTCTG GGGGGCCTCT TGCTGCTGGC CCTGCTGGTC 
CTGGCACTGT GGAAGCTCGG TTTTTTTAAA AGTGCCAAGC GCAAGAGGGA ACCTGGCCTA 
GGCCCCATCC CCAAAGAGCT CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Overexpression of integrin ?11 induces cardiac fibrosis in mice.
Acta physiologica (Oxford, England)(2017 Aug)
Romaine A,S?rensen IW,Zeltz C,Lu N,Erusappan PM,Melleby AO,Zhang L,Bendiksen B,Robinson EL,Aronsen JM,Herum KM,Danielsen HE,Sjaastad I,Christensen G,Gullberg D

The ?11 integrin mediates fibroblast-extracellular matrix-cardiomyocyte interactions in health and disease.
American journal of physiology. Heart and circulatory physiology311(1)H96-H106(2016 Jul)
Civitarese RA,Talior-Volodarsky I,Desjardins JF,Kabir G,Switzer J,Mitchell M,Kapus A,McCulloch CA,Gullberg D,Connelly KA

Stromal Integrin ?11?1 Affects RM11 Prostate and 4T1 Breast Xenograft Tumors Differently.
PloS one11(3)e0151663(2016)
Reigstad I,Smeland HY,Skogstrand T,Sortland K,Schmid MC,Reed RK,Stuhr L

Mmu-miR-126a-3p plays a role in murine embryo implantation by regulating Itga11.
Reproductive biomedicine online31(3)384-93(2015 Sep)
Li Z,Jia J,Gou J,Tong A,Liu X,Zhao X,Yi T

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Itga11 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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