H2bc6 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	H2bc6
Entrez Gene ID	319179
Full Name	histone cluster 1, H2be
General protein information	Preferred Names histone cluster 1, H2be Names histone H2B type 1-C/E/G histone 1, H2be
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 A3.1
Summary	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family and generates multiple transcripts through alternative splicing, the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Aug 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_178194.4	NP_835501.1	histone H2B type 1-C/E/G
NM_001177653.1	NP_001171124.1	histone H2B type 1-C/E/G
NM_001290530.1	NP_001277459.1	histone H2B type 1-C/E/G

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC618012	XP_002695948.2
Canis lupus familiaris (dog)	LOC100856099	XP_003640205.1
Pan troglodytes (chimpanzee)	LOC471880	XP_527258.1
Mus musculus (house mouse)	Hist1h2be	NP_001171124.1
Homo sapiens (human)	HIST1H2BF	NP_003513.1
Rattus norvegicus (Norway rat)	LOC100365043	XP_006254051.1

Gene Ontology
Bibliography

Related articles in PubMed

Histone H2B as a functionally important plasminogen receptor on macrophages.
Das R, Burke T, Plow EF
Blood110(10)3763-72(2007 Nov)

The human and mouse replication-dependent histone genes.
Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ
Genomics80(5)487-98(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following H2bc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the H2bc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu13934	NM_178194.4 Latest version!	Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu13934	NM_001290530.1 Latest version!	Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu13934	NM_001177653.1 Latest version!	Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

H2bc6 ( NM_178194.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_835501.1 Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu13934
Clone ID Related Accession (Same CDS sequence)	NM_178194.4 , NM_001177653.1 , NM_001290530.1
Accession Version	NM_178194.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	histone H2B type 1-C/E/G
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK030546.1, AK049948.1 and BF471999.1. On Apr 22, 2010 this sequence version replaced NM_178194.3. Transcript Variant: This variant (2) lacks internal 4 nts at an alternate splice site in the 5' UTR, as compared to variant 1. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK030546.1, SRR1660821.38066.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTGAGC CAGCCAAGTC CGCTCCCGCC CCGAAGAAGG GCTCCAAGAA GGCTGTCACC 
AAGGCCCAGA AGAAGGACGG CAAGAAGCGC AAGCGCAGCC GCAAGGAGAG CTACTCGGTG 
TACGTGTACA AGGTGCTGAA GCAAGTGCAC CCCGACACCG GCATCTCCTC CAAGGCCATG 
GGCATCATGA ACTCGTTCGT GAACGACATC TTCGAGCGCA TCGCGGGCGA GGCGTCCCGC 
CTGGCGCATT ACAACAAGCG CTCGACCATC ACATCCCGGG AGATCCAGAC GGCCGTGCGC 
CTGCTGCTGC CCGGGGAGCT GGCCAAGCAC GCGGTGTCGG AGGGCACCAA GGCTGTCACC 
AAGTACACCA GCTCCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_835501.1
CDS	220..600
Translation	MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK

Target ORF information:

RefSeq Version	NM_178194.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178194.4

ORF Insert Sequence:

ATGCCTGAGC CAGCCAAGTC CGCTCCCGCC CCGAAGAAGG GCTCCAAGAA GGCTGTCACC 
AAGGCCCAGA AGAAGGACGG CAAGAAGCGC AAGCGCAGCC GCAAGGAGAG CTACTCGGTG 
TACGTGTACA AGGTGCTGAA GCAAGTGCAC CCCGACACCG GCATCTCCTC CAAGGCCATG 
GGCATCATGA ACTCGTTCGT GAACGACATC TTCGAGCGCA TCGCGGGCGA GGCGTCCCGC 
CTGGCGCATT ACAACAAGCG CTCGACCATC ACATCCCGGG AGATCCAGAC GGCCGTGCGC 
CTGCTGCTGC CCGGGGAGCT GGCCAAGCAC GCGGTGTCGG AGGGCACCAA GGCTGTCACC 
AAGTACACCA GCTCCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

H2bc6 ( NM_001177653.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001171124.1 Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu13934
Clone ID Related Accession (Same CDS sequence)	NM_178194.4 , NM_001177653.1 , NM_001290530.1
Accession Version	NM_001177653.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Mus musculus(house mouse)
Product	histone H2B type 1-C/E/G
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK049948.1, AK030546.1 and BF471999.1. Transcript Variant: This variant (1) and variants 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK049948.1, SRR1660825.61310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTGAGC CAGCCAAGTC CGCTCCCGCC CCGAAGAAGG GCTCCAAGAA GGCTGTCACC 
AAGGCCCAGA AGAAGGACGG CAAGAAGCGC AAGCGCAGCC GCAAGGAGAG CTACTCGGTG 
TACGTGTACA AGGTGCTGAA GCAAGTGCAC CCCGACACCG GCATCTCCTC CAAGGCCATG 
GGCATCATGA ACTCGTTCGT GAACGACATC TTCGAGCGCA TCGCGGGCGA GGCGTCCCGC 
CTGGCGCATT ACAACAAGCG CTCGACCATC ACATCCCGGG AGATCCAGAC GGCCGTGCGC 
CTGCTGCTGC CCGGGGAGCT GGCCAAGCAC GCGGTGTCGG AGGGCACCAA GGCTGTCACC 
AAGTACACCA GCTCCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171124.1
CDS	194..574
Translation	MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK

Target ORF information:

RefSeq Version	NM_001177653.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001177653.1

ORF Insert Sequence:

ATGCCTGAGC CAGCCAAGTC CGCTCCCGCC CCGAAGAAGG GCTCCAAGAA GGCTGTCACC 
AAGGCCCAGA AGAAGGACGG CAAGAAGCGC AAGCGCAGCC GCAAGGAGAG CTACTCGGTG 
TACGTGTACA AGGTGCTGAA GCAAGTGCAC CCCGACACCG GCATCTCCTC CAAGGCCATG 
GGCATCATGA ACTCGTTCGT GAACGACATC TTCGAGCGCA TCGCGGGCGA GGCGTCCCGC 
CTGGCGCATT ACAACAAGCG CTCGACCATC ACATCCCGGG AGATCCAGAC GGCCGTGCGC 
CTGCTGCTGC CCGGGGAGCT GGCCAAGCAC GCGGTGTCGG AGGGCACCAA GGCTGTCACC 
AAGTACACCA GCTCCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

H2bc6 ( NM_001290530.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001277459.1 Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu13934
Clone ID Related Accession (Same CDS sequence)	NM_178194.4 , NM_001177653.1 , NM_001290530.1
Accession Version	NM_001290530.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	histone H2B type 1-C/E/G
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK049948.1. Transcript Variant: This variant (3) is intronless and contains a palindromic termination sequence instead of a polyA signal and tail. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AK049948.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTGAGC CAGCCAAGTC CGCTCCCGCC CCGAAGAAGG GCTCCAAGAA GGCTGTCACC 
AAGGCCCAGA AGAAGGACGG CAAGAAGCGC AAGCGCAGCC GCAAGGAGAG CTACTCGGTG 
TACGTGTACA AGGTGCTGAA GCAAGTGCAC CCCGACACCG GCATCTCCTC CAAGGCCATG 
GGCATCATGA ACTCGTTCGT GAACGACATC TTCGAGCGCA TCGCGGGCGA GGCGTCCCGC 
CTGGCGCATT ACAACAAGCG CTCGACCATC ACATCCCGGG AGATCCAGAC GGCCGTGCGC 
CTGCTGCTGC CCGGGGAGCT GGCCAAGCAC GCGGTGTCGG AGGGCACCAA GGCTGTCACC 
AAGTACACCA GCTCCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277459.1
CDS	15..395
Translation	MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK

Target ORF information:

RefSeq Version	NM_001290530.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus H2B clustered histone 6 (H2bc6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290530.1

ORF Insert Sequence:

ATGCCTGAGC CAGCCAAGTC CGCTCCCGCC CCGAAGAAGG GCTCCAAGAA GGCTGTCACC 
AAGGCCCAGA AGAAGGACGG CAAGAAGCGC AAGCGCAGCC GCAAGGAGAG CTACTCGGTG 
TACGTGTACA AGGTGCTGAA GCAAGTGCAC CCCGACACCG GCATCTCCTC CAAGGCCATG 
GGCATCATGA ACTCGTTCGT GAACGACATC TTCGAGCGCA TCGCGGGCGA GGCGTCCCGC 
CTGGCGCATT ACAACAAGCG CTCGACCATC ACATCCCGGG AGATCCAGAC GGCCGTGCGC 
CTGCTGCTGC CCGGGGAGCT GGCCAAGCAC GCGGTGTCGG AGGGCACCAA GGCTGTCACC 
AAGTACACCA GCTCCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Histone H2B as a functionally important plasminogen receptor on macrophages.
Blood110(10)3763-72(2007 Nov)
Das R,Burke T,Plow EF

The human and mouse replication-dependent histone genes.
Genomics80(5)487-98(2002 Nov)
Marzluff WF,Gongidi P,Woods KR,Jin J,Maltais LJ

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H2bc6 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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