Rnf19a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rnf19a
Entrez Gene ID	30945
Full Name	ring finger protein 19A
Synonyms	AA032313,Dorfin,Rnf19,UIP117,Ubce7ip2,XYbp
General protein information	Preferred Names ring finger protein 19A Names E3 ubiquitin-protein ligase RNF19A UBCM4-interacting protein 117 XY body protein double ring-finger protein gametogenesis-expressed protein GEG-154 ring finger protein (C3HC4 type) 19 ubiquitin conjugating enzyme 7 interacting protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 B3.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006520081.3	XP_006520144.1	E3 ubiquitin-protein ligase RNF19A isoform X1
NM_013923.2	NP_038951.1	E3 ubiquitin-protein ligase RNF19A
NM_001357631.1	NP_001344560.1	E3 ubiquitin-protein ligase RNF19A

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	RNF19A	XP_418362.3
	RNF19A	XP_002805474.1
Xenopus tropicalis (tropical clawed frog)	rnf19a	NP_001116899.1
Homo sapiens (human)	RNF19A	NP_001267468.1
Pan troglodytes (chimpanzee)	RNF19A	XP_001152507.1
Bos taurus (cattle)	RNF19A	NP_001178260.1
Danio rerio (zebrafish)	LOC557995	XP_686250.4
Canis lupus familiaris (dog)	RNF19A	XP_848454.1
Rattus norvegicus (Norway rat)	Rnf19a	NP_001124032.1
Mus musculus (house mouse)	Rnf19a	NP_038951.1

Gene Ontology
Bibliography

Related articles in PubMed

Mice lacking the PSD-95-interacting E3 ligase, Dorfin/Rnf19a, display reduced adult neurogenesis, enhanced long-term potentiation, and impaired contextual fear conditioning.
Park H, Yang J, Kim R, Li Y, Lee Y, Lee C, Park J, Lee D, Kim H, Kim E
Scientific reports516410(2015 Nov)

Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.
Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G
Journal of neuroscience research88(1)123-35(2010 Jan)

Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.
Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G
The Journal of biological chemistry282(38)28087-95(2007 Sep)

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.
Evsikov AV, Graber JH, Brockman JM, Hampl A, Holbrook AE, Singh P, Eppig JJ, Solter D, Knowles BB
Genes & development20(19)2713-27(2006 Oct)

Transcriptome analysis of mouse stem cells and early embryos.
Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MS
PLoS biology1(3)E74(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that Dorfin may regulate adult neurogenesis, synaptic plasticity, and contextual fear memory.
Title: Mice lacking the PSD-95-interacting E3 ligase, Dorfin/Rnf19a, display reduced adult neurogenesis, enhanced long-term potentiation, and impaired contextual fear conditioning.

In addition to causing a decrease in the amount of mutant SOD1 protein in the spinal cord, Dorfin overexpression ameliorated neurological phenotypes and motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis.
Title: Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.

Dorfin ubiquitylated mutant SOD1 by recognizing the Cys(6)- and Cys(111)-disulfide cross-linked form and targeted it for proteasomal degradation
Title: Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.

The following Rnf19a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rnf19a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu50698	NM_001357631.1 Latest version!	Mus musculus ring finger protein 19A (Rnf19a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu50698	XM_006520081.3 Latest version!	Mus musculus ring finger protein 19A (Rnf19a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu10166	NM_013923.2 Latest version!	Mus musculus ring finger protein 19A (Rnf19a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rnf19a ( NM_001357631.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001344560.1 Mus musculus ring finger protein 19A (Rnf19a), mRNA.

Price & Availability↑

CloneID	OMu50698
Clone ID Related Accession (Same CDS sequence)	XM_006520081.3 , NM_001357631.1
Accession Version	NM_001357631.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	E3 ubiquitin-protein ligase RNF19A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC147366.5 and AC121577.3. On Nov 4, 2017 this sequence version replaced XM_006520081.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK082665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGCAAGAAC AAGAAATAAG TTTTATTTTT AAGTATAATG AAGGGCTGTG TATGAACATT 
GACTCTGACT CAATTCTGAT GAGCATTTTA GACATGAGTT TACATCAGCA AATGGGCTCA 
GATAGAGATC TTCAGTCTTC TACTTCCTCC GTGAGCTTGC CTTCTGTCAA AAAGGCACCC 
AAACAGAGAA GGATTTCAAT AGGCTCTCTC TTTCGGAGGA AGAAGGACAG CAAACGAAAA 
TCAAGGGAGC TCAATGGTGG AGTGGATGGA ATTGCAAGTA TTGAGAGTAT ACATTCTGAA 
ATGTGTGCTG ATAAGAACTC CATTTTCTCT ACAAATACCT CTTCTGACAA TGGATTGACT 
TCCATCAGCA AACAAATTGG AGACTTTATA GAATGTCCTT TGTGCCTTTT ACGGCATTCT 
AAAGACAGAT TTCCTGATAT AATGACATGC CACCATAGAT CTTGTGTGGA TTGCTTACGA 
CAATACCTAA GGATAGAAAT CTCTGAAAGT AGAGTTAATA TCAGTTGTCC AGAATGCACT 
GAACGGTTTA ATCCTCATGA CATTCGCTTG ATATTAAGTG ATGATGTCTT AATGGAAAAA 
TATGAAGAAT TTATGCTTCG ACGGTGGCTT GTTGCAGATC CTGACTGTAG GTGGTGTCCG 
GCTCCAGACT GTGGATACGC TGTGATAGCA TTTGGATGTG CCAGCTGTCC AAAACTAACT 
TGTGGGCGAG AAGGCTGTGG AACAGAGTTT TGCTACCACT GTAAACAGAT CTGGCATCCA 
AACCAGACCT GTGATGCTGC TCGACAGGAA AGAGCCCAAA GTTTACGCTT AAGAACTATA 
CGTTCTTCAT CTATTAGTTA CAGCCAGGAA TCTGGAGCAG CAGCTGATGA TATAAAGCCA 
TGTCCACGAT GTGCTGCTTA TATAATAAAG ATGAATGATG GGAGTTGCAA TCATATGACA 
TGTGCTGTCT GTGGTTGTGA GTTTTGTTGG CTATGTATGA AAGAAATCTC CGATTTACAT 
TATCTAAGTC CCTCAGGTTG TACTTTTTGG GGGAAGAAAC CCTGGAGCCG AAAGAAGAAA 
ATCCTGTGGC AGCTGGGAAC CCTTGTTGGT GCTCCCGTAG GGATTGCTCT CATAGCTGGC 
ATTGCCATTC CCGCCATGAT CATTGGCATT CCTGTGTACG TGGGCCGCAA GATTCATAAT 
CGCTATGAAG GCAAAGATGT TTCAAAACAT AAGCGGAATC TGGCCATAGC AGGCGGTGTC 
ACCCTGTCTG TAATCGTGTC TCCGGTGGTA GCTGCAGTGA CTGTAGGCAT TGGTGTTCCC 
ATCATGCTAG CTTATGTCTA TGGTGTGGTC CCAATTTCTC TCTGCCGAAG TGGGGGTTGT 
GGTGTCTCTG CGGGCAATGG GAAAGGAGTG AGGATTGAGT TTGATGATGA GAATGACATA 
AACGTCGGTG GGACTAACGC AGCCATAGAG AAGGGAACAG CATGGAAGTG CAAGTGGATA 
TTGAGTCAAA GCCATTCAAG TTCCGACACA ACAGTGGAAG CAGCAGTGTG GATGACAGTG 
GTGCTACCCG AGGCCACACA GGCGGGGCGT CCAGTGGCTT GCCCGAAGGT AAATCCAGTG 
CTACCAAGTG GTCCAAGGAA GCAACAGGAG GAAAAAAGTC AAAAAGTGGT AAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001344560.1
CDS	319..1995
Translation	MQEQEISFIFKYNEGLCMNIDSDSILMSILDMSLHQQMGSDRDLQSSTSSVSLPSVKKAPKQRRISIGSLFRRKKDSKRKSRELNGGVDGIASIESIHSEMCADKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIEKGTAWKCKWILSQSHSSSDTTVEAAVWMTVVLPEATQAGRPVACPKVNPVLPSGPRKQQEEKSQKVVN

Target ORF information:

RefSeq Version	NM_001357631.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ring finger protein 19A (Rnf19a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001357631.1

ORF Insert Sequence:

ATGCAAGAAC AAGAAATAAG TTTTATTTTT AAGTATAATG AAGGGCTGTG TATGAACATT 
GACTCTGACT CAATTCTGAT GAGCATTTTA GACATGAGTT TACATCAGCA AATGGGCTCA 
GATAGAGATC TTCAGTCTTC TACTTCCTCC GTGAGCTTGC CTTCTGTCAA AAAGGCACCC 
AAACAGAGAA GGATTTCAAT AGGCTCTCTC TTTCGGAGGA AGAAGGACAG CAAACGAAAA 
TCAAGGGAGC TCAATGGTGG AGTGGATGGA ATTGCAAGTA TTGAGAGTAT ACATTCTGAA 
ATGTGTGCTG ATAAGAACTC CATTTTCTCT ACAAATACCT CTTCTGACAA TGGATTGACT 
TCCATCAGCA AACAAATTGG AGACTTTATA GAATGTCCTT TGTGCCTTTT ACGGCATTCT 
AAAGACAGAT TTCCTGATAT AATGACATGC CACCATAGAT CTTGTGTGGA TTGCTTACGA 
CAATACCTAA GGATAGAAAT CTCTGAAAGT AGAGTTAATA TCAGTTGTCC AGAATGCACT 
GAACGGTTTA ATCCTCATGA CATTCGCTTG ATATTAAGTG ATGATGTCTT AATGGAAAAA 
TATGAAGAAT TTATGCTTCG ACGGTGGCTT GTTGCAGATC CTGACTGTAG GTGGTGTCCG 
GCTCCAGACT GTGGATACGC TGTGATAGCA TTTGGATGTG CCAGCTGTCC AAAACTAACT 
TGTGGGCGAG AAGGCTGTGG AACAGAGTTT TGCTACCACT GTAAACAGAT CTGGCATCCA 
AACCAGACCT GTGATGCTGC TCGACAGGAA AGAGCCCAAA GTTTACGCTT AAGAACTATA 
CGTTCTTCAT CTATTAGTTA CAGCCAGGAA TCTGGAGCAG CAGCTGATGA TATAAAGCCA 
TGTCCACGAT GTGCTGCTTA TATAATAAAG ATGAATGATG GGAGTTGCAA TCATATGACA 
TGTGCTGTCT GTGGTTGTGA GTTTTGTTGG CTATGTATGA AAGAAATCTC CGATTTACAT 
TATCTAAGTC CCTCAGGTTG TACTTTTTGG GGGAAGAAAC CCTGGAGCCG AAAGAAGAAA 
ATCCTGTGGC AGCTGGGAAC CCTTGTTGGT GCTCCCGTAG GGATTGCTCT CATAGCTGGC 
ATTGCCATTC CCGCCATGAT CATTGGCATT CCTGTGTACG TGGGCCGCAA GATTCATAAT 
CGCTATGAAG GCAAAGATGT TTCAAAACAT AAGCGGAATC TGGCCATAGC AGGCGGTGTC 
ACCCTGTCTG TAATCGTGTC TCCGGTGGTA GCTGCAGTGA CTGTAGGCAT TGGTGTTCCC 
ATCATGCTAG CTTATGTCTA TGGTGTGGTC CCAATTTCTC TCTGCCGAAG TGGGGGTTGT 
GGTGTCTCTG CGGGCAATGG GAAAGGAGTG AGGATTGAGT TTGATGATGA GAATGACATA 
AACGTCGGTG GGACTAACGC AGCCATAGAG AAGGGAACAG CATGGAAGTG CAAGTGGATA 
TTGAGTCAAA GCCATTCAAG TTCCGACACA ACAGTGGAAG CAGCAGTGTG GATGACAGTG 
GTGCTACCCG AGGCCACACA GGCGGGGCGT CCAGTGGCTT GCCCGAAGGT AAATCCAGTG 
CTACCAAGTG GTCCAAGGAA GCAACAGGAG GAAAAAAGTC AAAAAGTGGT AAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnf19a ( XM_006520081.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520144.1 Mus musculus ring finger protein 19A (Rnf19a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50698
Clone ID Related Accession (Same CDS sequence)	XM_006520081.3 , NM_001357631.1
Accession Version	XM_006520081.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	E3 ubiquitin-protein ligase RNF19A isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520081.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAGAAC AAGAAATAAG TTTTATTTTT AAGTATAATG AAGGGCTGTG TATGAACATT 
GACTCTGACT CAATTCTGAT GAGCATTTTA GACATGAGTT TACATCAGCA AATGGGCTCA 
GATAGAGATC TTCAGTCTTC TACTTCCTCC GTGAGCTTGC CTTCTGTCAA AAAGGCACCC 
AAACAGAGAA GGATTTCAAT AGGCTCTCTC TTTCGGAGGA AGAAGGACAG CAAACGAAAA 
TCAAGGGAGC TCAATGGTGG AGTGGATGGA ATTGCAAGTA TTGAGAGTAT ACATTCTGAA 
ATGTGTGCTG ATAAGAACTC CATTTTCTCT ACAAATACCT CTTCTGACAA TGGATTGACT 
TCCATCAGCA AACAAATTGG AGACTTTATA GAATGTCCTT TGTGCCTTTT ACGGCATTCT 
AAAGACAGAT TTCCTGATAT AATGACATGC CACCATAGAT CTTGTGTGGA TTGCTTACGA 
CAATACCTAA GGATAGAAAT CTCTGAAAGT AGAGTTAATA TCAGTTGTCC AGAATGCACT 
GAACGGTTTA ATCCTCATGA CATTCGCTTG ATATTAAGTG ATGATGTCTT AATGGAAAAA 
TATGAAGAAT TTATGCTTCG ACGGTGGCTT GTTGCAGATC CTGACTGTAG GTGGTGTCCG 
GCTCCAGACT GTGGATACGC TGTGATAGCA TTTGGATGTG CCAGCTGTCC AAAACTAACT 
TGTGGGCGAG AAGGCTGTGG AACAGAGTTT TGCTACCACT GTAAACAGAT CTGGCATCCA 
AACCAGACCT GTGATGCTGC TCGACAGGAA AGAGCCCAAA GTTTACGCTT AAGAACTATA 
CGTTCTTCAT CTATTAGTTA CAGCCAGGAA TCTGGAGCAG CAGCTGATGA TATAAAGCCA 
TGTCCACGAT GTGCTGCTTA TATAATAAAG ATGAATGATG GGAGTTGCAA TCATATGACA 
TGTGCTGTCT GTGGTTGTGA GTTTTGTTGG CTATGTATGA AAGAAATCTC CGATTTACAT 
TATCTAAGTC CCTCAGGTTG TACTTTTTGG GGGAAGAAAC CCTGGAGCCG AAAGAAGAAA 
ATCCTGTGGC AGCTGGGAAC CCTTGTTGGT GCTCCCGTAG GGATTGCTCT CATAGCTGGC 
ATTGCCATTC CCGCCATGAT CATTGGCATT CCTGTGTACG TGGGCCGCAA GATTCATAAT 
CGCTATGAAG GCAAAGATGT TTCAAAACAT AAGCGGAATC TGGCCATAGC AGGCGGTGTC 
ACCCTGTCTG TAATCGTGTC TCCGGTGGTA GCTGCAGTGA CTGTAGGCAT TGGTGTTCCC 
ATCATGCTAG CTTATGTCTA TGGTGTGGTC CCAATTTCTC TCTGCCGAAG TGGGGGTTGT 
GGTGTCTCTG CGGGCAATGG GAAAGGAGTG AGGATTGAGT TTGATGATGA GAATGACATA 
AACGTCGGTG GGACTAACGC AGCCATAGAG AAGGGAACAG CATGGAAGTG CAAGTGGATA 
TTGAGTCAAA GCCATTCAAG TTCCGACACA ACAGTGGAAG CAGCAGTGTG GATGACAGTG 
GTGCTACCCG AGGCCACACA GGCGGGGCGT CCAGTGGCTT GCCCGAAGGT AAATCCAGTG 
CTACCAAGTG GTCCAAGGAA GCAACAGGAG GAAAAAAGTC AAAAAGTGGT AAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520144.1
CDS	270..1946
Translation	MQEQEISFIFKYNEGLCMNIDSDSILMSILDMSLHQQMGSDRDLQSSTSSVSLPSVKKAPKQRRISIGSLFRRKKDSKRKSRELNGGVDGIASIESIHSEMCADKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIEKGTAWKCKWILSQSHSSSDTTVEAAVWMTVVLPEATQAGRPVACPKVNPVLPSGPRKQQEEKSQKVVN

Target ORF information:

RefSeq Version	XM_006520081.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus ring finger protein 19A (Rnf19a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520081.3

ORF Insert Sequence:

ATGCAAGAAC AAGAAATAAG TTTTATTTTT AAGTATAATG AAGGGCTGTG TATGAACATT 
GACTCTGACT CAATTCTGAT GAGCATTTTA GACATGAGTT TACATCAGCA AATGGGCTCA 
GATAGAGATC TTCAGTCTTC TACTTCCTCC GTGAGCTTGC CTTCTGTCAA AAAGGCACCC 
AAACAGAGAA GGATTTCAAT AGGCTCTCTC TTTCGGAGGA AGAAGGACAG CAAACGAAAA 
TCAAGGGAGC TCAATGGTGG AGTGGATGGA ATTGCAAGTA TTGAGAGTAT ACATTCTGAA 
ATGTGTGCTG ATAAGAACTC CATTTTCTCT ACAAATACCT CTTCTGACAA TGGATTGACT 
TCCATCAGCA AACAAATTGG AGACTTTATA GAATGTCCTT TGTGCCTTTT ACGGCATTCT 
AAAGACAGAT TTCCTGATAT AATGACATGC CACCATAGAT CTTGTGTGGA TTGCTTACGA 
CAATACCTAA GGATAGAAAT CTCTGAAAGT AGAGTTAATA TCAGTTGTCC AGAATGCACT 
GAACGGTTTA ATCCTCATGA CATTCGCTTG ATATTAAGTG ATGATGTCTT AATGGAAAAA 
TATGAAGAAT TTATGCTTCG ACGGTGGCTT GTTGCAGATC CTGACTGTAG GTGGTGTCCG 
GCTCCAGACT GTGGATACGC TGTGATAGCA TTTGGATGTG CCAGCTGTCC AAAACTAACT 
TGTGGGCGAG AAGGCTGTGG AACAGAGTTT TGCTACCACT GTAAACAGAT CTGGCATCCA 
AACCAGACCT GTGATGCTGC TCGACAGGAA AGAGCCCAAA GTTTACGCTT AAGAACTATA 
CGTTCTTCAT CTATTAGTTA CAGCCAGGAA TCTGGAGCAG CAGCTGATGA TATAAAGCCA 
TGTCCACGAT GTGCTGCTTA TATAATAAAG ATGAATGATG GGAGTTGCAA TCATATGACA 
TGTGCTGTCT GTGGTTGTGA GTTTTGTTGG CTATGTATGA AAGAAATCTC CGATTTACAT 
TATCTAAGTC CCTCAGGTTG TACTTTTTGG GGGAAGAAAC CCTGGAGCCG AAAGAAGAAA 
ATCCTGTGGC AGCTGGGAAC CCTTGTTGGT GCTCCCGTAG GGATTGCTCT CATAGCTGGC 
ATTGCCATTC CCGCCATGAT CATTGGCATT CCTGTGTACG TGGGCCGCAA GATTCATAAT 
CGCTATGAAG GCAAAGATGT TTCAAAACAT AAGCGGAATC TGGCCATAGC AGGCGGTGTC 
ACCCTGTCTG TAATCGTGTC TCCGGTGGTA GCTGCAGTGA CTGTAGGCAT TGGTGTTCCC 
ATCATGCTAG CTTATGTCTA TGGTGTGGTC CCAATTTCTC TCTGCCGAAG TGGGGGTTGT 
GGTGTCTCTG CGGGCAATGG GAAAGGAGTG AGGATTGAGT TTGATGATGA GAATGACATA 
AACGTCGGTG GGACTAACGC AGCCATAGAG AAGGGAACAG CATGGAAGTG CAAGTGGATA 
TTGAGTCAAA GCCATTCAAG TTCCGACACA ACAGTGGAAG CAGCAGTGTG GATGACAGTG 
GTGCTACCCG AGGCCACACA GGCGGGGCGT CCAGTGGCTT GCCCGAAGGT AAATCCAGTG 
CTACCAAGTG GTCCAAGGAA GCAACAGGAG GAAAAAAGTC AAAAAGTGGT AAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rnf19a ( NM_013923.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038951.1 Mus musculus ring finger protein 19A (Rnf19a), mRNA.

Price & Availability↑

CloneID	OMu10166
Clone ID Related Accession (Same CDS sequence)	NM_013923.2
Accession Version	NM_013923.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	E3 ubiquitin-protein ligase RNF19A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY207861.1, AK147768.1, CO432840.1, DV656092.1 and CN695058.1. On Mar 24, 2007 this sequence version replaced NM_013923.1. ##Evidence-Data-START## Transcript exon combination :: AK147768.1, SRR1660813.36883.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAGAAC AAGAAATAAG TTTTATTTTT AAGTATAATG AAGGGCTGTG TATGAACATT 
GACTCTGACT CAATTCTGAT GAGCATTTTA GACATGAGTT TACATCAGCA AATGGGCTCA 
GATAGAGATC TTCAGTCTTC TACTTCCTCC GTGAGCTTGC CTTCTGTCAA AAAGGCACCC 
AAACAGAGAA GGATTTCAAT AGGCTCTCTC TTTCGGAGGA AGAAGGACAG CAAACGAAAA 
TCAAGGGAGC TCAATGGTGG AGTGGATGGA ATTGCAAGTA TTGAGAGTAT ACATTCTGAA 
ATGTGTGCTG ATAAGAACTC CATTTTCTCT ACAAATACCT CTTCTGACAA TGGATTGACT 
TCCATCAGCA AACAAATTGG AGACTTTATA GAATGTCCTT TGTGCCTTTT ACGGCATTCT 
AAAGACAGAT TTCCTGATAT AATGACATGC CACCATAGAT CTTGTGTGGA TTGCTTACGA 
CAATACCTAA GGATAGAAAT CTCTGAAAGT AGAGTTAATA TCAGTTGTCC AGAATGCACT 
GAACGGTTTA ATCCTCATGA CATTCGCTTG ATATTAAGTG ATGATGTCTT AATGGAAAAA 
TATGAAGAAT TTATGCTTCG ACGGTGGCTT GTTGCAGATC CTGACTGTAG GTGGTGTCCG 
GCTCCAGACT GTGGATACGC TGTGATAGCA TTTGGATGTG CCAGCTGTCC AAAACTAACT 
TGTGGGCGAG AAGGCTGTGG AACAGAGTTT TGCTACCACT GTAAACAGAT CTGGCATCCA 
AACCAGACCT GTGATGCTGC TCGACAGGAA AGAGCCCAAA GTTTACGCTT AAGAACTATA 
CGTTCTTCAT CTATTAGTTA CAGCCAGGAA TCTGGAGCAG CAGCTGATGA TATAAAGCCA 
TGTCCACGAT GTGCTGCTTA TATAATAAAG ATGAATGATG GGAGTTGCAA TCATATGACA 
TGTGCTGTCT GTGGTTGTGA GTTTTGTTGG CTATGTATGA AAGAAATCTC CGATTTACAT 
TATCTAAGTC CCTCAGGTTG TACTTTTTGG GGGAAGAAAC CCTGGAGCCG AAAGAAGAAA 
ATCCTGTGGC AGCTGGGAAC CCTTGTTGGT GCTCCCGTAG GGATTGCTCT CATAGCTGGC 
ATTGCCATTC CCGCCATGAT CATTGGCATT CCTGTGTACG TGGGCCGCAA GATTCATAAT 
CGCTATGAAG GCAAAGATGT TTCAAAACAT AAGCGGAATC TGGCCATAGC AGGCGGTGTC 
ACCCTGTCTG TAATCGTGTC TCCGGTGGTA GCTGCAGTGA CTGTAGGCAT TGGTGTTCCC 
ATCATGCTAG CTTATGTCTA TGGTGTGGTC CCAATTTCTC TCTGCCGAAG TGGGGGTTGT 
GGTGTCTCTG CGGGCAATGG GAAAGGAGTG AGGATTGAGT TTGATGATGA GAATGACATA 
AACGTCGGTG GGACTAACGC AGCCATAGAT ACAACATCAG TAGCAGAAGC AAGGCACAAC 
CCTAGCATAG GAGAGGGAAG TGTCGGCGGC CTGACTGGCA GTTTGAGTGC AAGTGGAAGC 
CACATGGATC GAATAGGCAC CATTAGAGAC AACCTGAGTG AGACAGCGAG CACCATGGCA 
TTAGCTGGAG CTAGTATCAC GGGCAGTCTG TCGGGAAGTG CCATGGTAAA CTGTTTCAAC 
AGGTTGGAAG TACAAGCAGA CGTACAGAAA GAACGGTGTA GTCTCAGTGG AGAGTCTGGC 
ACAGTGAGCT TGGGAACAGT TAGTGATAAC GCCAGCACCA AAGCAATGGC GGGATCCATT 
CTCAACTCCT ACATCCCTCT GGACAGAGAA GGGAACAGCA TGGAAGTGCA AGTGGATATT 
GAGTCAAAGC CATTCAAGTT CCGACACAAC AGTGGAAGCA GCAGTGTGGA TGACAGTGGT 
GCTACCCGAG GCCACACAGG CGGGGCGTCC AGTGGCTTGC CCGAAGGTAA ATCCAGTGCT 
ACCAAGTGGT CCAAGGAAGC AACAGGAGGA AAAAAGTCAA AAAGTGGTAA ACTGAGGAAA 
AAGGGTAACA TGAAGATCAA TGAGACCAGA GAGGACATGG ATGCACAGTT GTTAGAGCAA 
CAAAGCACGA ACTCAAGTGA GTTTGAGGCG CCATCCCTCA GTGACAGCAT GCCGTCTGTA 
GCAGATTCCC ACTCCAGTCA TTTTTCTGAA TTTAGCTGCT CAGACTTAGA AAGCATGAGA 
ACGTCCTGTA GTCACGGCTC CAGTGATTGC CACGCCCGCT TCACAGCTGT GAACACCCTT 
CCTGAGGTAG AAAACGACCG ACTGGAGAAC TCACCACACC AGTGCAGCAG CGCTCTGCTT 
TCCAAAGCTG CTTCCTGTTC AGATGTCCCA CAGCCCAGCC ATGCTGCAGA CGAGCATGGC 
ACCAGCAGAA GTGGGGGGAA GCCTATGGTG GATTTGTGTT TTGGTGATGC ACTGAGAGAG 
ACAAATAATA ACCACTCGCA CCAGACAGCA GACCTGAAAG TTGCTGTCCA GACTGAAATT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038951.1
CDS	319..2841
Translation	MQEQEISFIFKYNEGLCMNIDSDSILMSILDMSLHQQMGSDRDLQSSTSSVSLPSVKKAPKQRRISIGSLFRRKKDSKRKSRELNGGVDGIASIESIHSEMCADKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNAAIDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGTIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDREGNSMEVQVDIESKPFKFRHNSGSSSVDDSGATRGHTGGASSGLPEGKSSATKWSKEATGGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMRTSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSSALLSKAASCSDVPQPSHAADEHGTSRSGGKPMVDLCFGDALRETNNNHSHQTADLKVAVQTEI

Target ORF information:

RefSeq Version	NM_013923.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ring finger protein 19A (Rnf19a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013923.2

ORF Insert Sequence:

ATGCAAGAAC AAGAAATAAG TTTTATTTTT AAGTATAATG AAGGGCTGTG TATGAACATT 
GACTCTGACT CAATTCTGAT GAGCATTTTA GACATGAGTT TACATCAGCA AATGGGCTCA 
GATAGAGATC TTCAGTCTTC TACTTCCTCC GTGAGCTTGC CTTCTGTCAA AAAGGCACCC 
AAACAGAGAA GGATTTCAAT AGGCTCTCTC TTTCGGAGGA AGAAGGACAG CAAACGAAAA 
TCAAGGGAGC TCAATGGTGG AGTGGATGGA ATTGCAAGTA TTGAGAGTAT ACATTCTGAA 
ATGTGTGCTG ATAAGAACTC CATTTTCTCT ACAAATACCT CTTCTGACAA TGGATTGACT 
TCCATCAGCA AACAAATTGG AGACTTTATA GAATGTCCTT TGTGCCTTTT ACGGCATTCT 
AAAGACAGAT TTCCTGATAT AATGACATGC CACCATAGAT CTTGTGTGGA TTGCTTACGA 
CAATACCTAA GGATAGAAAT CTCTGAAAGT AGAGTTAATA TCAGTTGTCC AGAATGCACT 
GAACGGTTTA ATCCTCATGA CATTCGCTTG ATATTAAGTG ATGATGTCTT AATGGAAAAA 
TATGAAGAAT TTATGCTTCG ACGGTGGCTT GTTGCAGATC CTGACTGTAG GTGGTGTCCG 
GCTCCAGACT GTGGATACGC TGTGATAGCA TTTGGATGTG CCAGCTGTCC AAAACTAACT 
TGTGGGCGAG AAGGCTGTGG AACAGAGTTT TGCTACCACT GTAAACAGAT CTGGCATCCA 
AACCAGACCT GTGATGCTGC TCGACAGGAA AGAGCCCAAA GTTTACGCTT AAGAACTATA 
CGTTCTTCAT CTATTAGTTA CAGCCAGGAA TCTGGAGCAG CAGCTGATGA TATAAAGCCA 
TGTCCACGAT GTGCTGCTTA TATAATAAAG ATGAATGATG GGAGTTGCAA TCATATGACA 
TGTGCTGTCT GTGGTTGTGA GTTTTGTTGG CTATGTATGA AAGAAATCTC CGATTTACAT 
TATCTAAGTC CCTCAGGTTG TACTTTTTGG GGGAAGAAAC CCTGGAGCCG AAAGAAGAAA 
ATCCTGTGGC AGCTGGGAAC CCTTGTTGGT GCTCCCGTAG GGATTGCTCT CATAGCTGGC 
ATTGCCATTC CCGCCATGAT CATTGGCATT CCTGTGTACG TGGGCCGCAA GATTCATAAT 
CGCTATGAAG GCAAAGATGT TTCAAAACAT AAGCGGAATC TGGCCATAGC AGGCGGTGTC 
ACCCTGTCTG TAATCGTGTC TCCGGTGGTA GCTGCAGTGA CTGTAGGCAT TGGTGTTCCC 
ATCATGCTAG CTTATGTCTA TGGTGTGGTC CCAATTTCTC TCTGCCGAAG TGGGGGTTGT 
GGTGTCTCTG CGGGCAATGG GAAAGGAGTG AGGATTGAGT TTGATGATGA GAATGACATA 
AACGTCGGTG GGACTAACGC AGCCATAGAT ACAACATCAG TAGCAGAAGC AAGGCACAAC 
CCTAGCATAG GAGAGGGAAG TGTCGGCGGC CTGACTGGCA GTTTGAGTGC AAGTGGAAGC 
CACATGGATC GAATAGGCAC CATTAGAGAC AACCTGAGTG AGACAGCGAG CACCATGGCA 
TTAGCTGGAG CTAGTATCAC GGGCAGTCTG TCGGGAAGTG CCATGGTAAA CTGTTTCAAC 
AGGTTGGAAG TACAAGCAGA CGTACAGAAA GAACGGTGTA GTCTCAGTGG AGAGTCTGGC 
ACAGTGAGCT TGGGAACAGT TAGTGATAAC GCCAGCACCA AAGCAATGGC GGGATCCATT 
CTCAACTCCT ACATCCCTCT GGACAGAGAA GGGAACAGCA TGGAAGTGCA AGTGGATATT 
GAGTCAAAGC CATTCAAGTT CCGACACAAC AGTGGAAGCA GCAGTGTGGA TGACAGTGGT 
GCTACCCGAG GCCACACAGG CGGGGCGTCC AGTGGCTTGC CCGAAGGTAA ATCCAGTGCT 
ACCAAGTGGT CCAAGGAAGC AACAGGAGGA AAAAAGTCAA AAAGTGGTAA ACTGAGGAAA 
AAGGGTAACA TGAAGATCAA TGAGACCAGA GAGGACATGG ATGCACAGTT GTTAGAGCAA 
CAAAGCACGA ACTCAAGTGA GTTTGAGGCG CCATCCCTCA GTGACAGCAT GCCGTCTGTA 
GCAGATTCCC ACTCCAGTCA TTTTTCTGAA TTTAGCTGCT CAGACTTAGA AAGCATGAGA 
ACGTCCTGTA GTCACGGCTC CAGTGATTGC CACGCCCGCT TCACAGCTGT GAACACCCTT 
CCTGAGGTAG AAAACGACCG ACTGGAGAAC TCACCACACC AGTGCAGCAG CGCTCTGCTT 
TCCAAAGCTG CTTCCTGTTC AGATGTCCCA CAGCCCAGCC ATGCTGCAGA CGAGCATGGC 
ACCAGCAGAA GTGGGGGGAA GCCTATGGTG GATTTGTGTT TTGGTGATGC ACTGAGAGAG 
ACAAATAATA ACCACTCGCA CCAGACAGCA GACCTGAAAG TTGCTGTCCA GACTGAAATT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mice lacking the PSD-95-interacting E3 ligase, Dorfin/Rnf19a, display reduced adult neurogenesis, enhanced long-term potentiation, and impaired contextual fear conditioning.
Scientific reports516410(2015 Nov)
Park H,Yang J,Kim R,Li Y,Lee Y,Lee C,Park J,Lee D,Kim H,Kim E

Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.
Journal of neuroscience research88(1)123-35(2010 Jan)
Sone J,Niwa J,Kawai K,Ishigaki S,Yamada S,Adachi H,Katsuno M,Tanaka F,Doyu M,Sobue G

Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.
The Journal of biological chemistry282(38)28087-95(2007 Sep)
Niwa J,Yamada S,Ishigaki S,Sone J,Takahashi M,Katsuno M,Tanaka F,Doyu M,Sobue G

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.
Genes & development20(19)2713-27(2006 Oct)
Evsikov AV,Graber JH,Brockman JM,Hampl A,Holbrook AE,Singh P,Eppig JJ,Solter D,Knowles BB

Transcriptome analysis of mouse stem cells and early embryos.
PLoS biology1(3)E74(2003 Dec)
Sharov AA,Piao Y,Matoba R,Dudekula DB,Qian Y,VanBuren V,Falco G,Martin PR,Stagg CA,Bassey UC,Wang Y,Carter MG,Hamatani T,Aiba K,Akutsu H,Sharova L,Tanaka TS,Kimber WL,Yoshikawa T,Jaradat SA,Pantano S,Nagaraja R,Boheler KR,Taub D,Hodes RJ,Longo DL,Schlessinger D,Keller J,Klotz E,Kelsoe G,Umezawa A,Vescovi AL,Rossant J,Kunath T,Hogan BL,Curci A,D'Urso M,Kelso J,Hide W,Ko MS

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Rnf19a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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