Kdm3b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdm3b
Entrez Gene ID	277250
Full Name	KDM3B lysine (K)-specific demethylase 3B
Synonyms	5830462I21Rik,JHDM2B,Jmjd1b,mKIAA1082
General protein information	Preferred Names KDM3B lysine (K)-specific demethylase 3B Names lysine-specific demethylase 3B jmjC domain-containing histone demethylation protein 2B jumonji domain containing 1B jumonji domain-containing protein 1B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001081256.1	NP_001074725.1	lysine-specific demethylase 3B

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KDM3B	XP_517956.3
Mus musculus (house mouse)	Kdm3b	NP_001074725.1
Danio rerio (zebrafish)	wu:fe01c10	XP_005173195.1
	KDM3B	XP_002804573.1
Gallus gallus (chicken)	KDM3B	XP_004945121.1
Xenopus tropicalis (tropical clawed frog)	kdm3b	XP_002936894.1
Bos taurus (cattle)	KDM3B	XP_003586349.1
Homo sapiens (human)	KDM3B	NP_057688.2
Canis lupus familiaris (dog)	KDM3B	XP_531921.3
Rattus norvegicus (Norway rat)	Kdm3b	XP_006254677.1

Gene Ontology
Bibliography

Related articles in PubMed

The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function.
Liu Z, Chen X, Zhou S, Liao L, Jiang R, Xu J
International journal of biological sciences11(5)494-507(2015)

Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors.
Liu Z, Oyola MG, Zhou S, Chen X, Liao L, Tien JC, Mani SK, Xu J
International journal of biological sciences11(12)1447-57(2015)

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.
Burton A, Muller J, Tu S, Padilla-Longoria P, Guccione E, Torres-Padilla ME
Cell reports5(3)687-701(2013 Nov)

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Developmental cell18(4)675-85(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results demonstrate that Kdm3b-mediated H3K9 demethylation plays essential roles in maintenance of the circulating IGF-1, postnatal somatic growth, circulating 17beta-estradiol, and female reproductive function.
Title: The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function.

findings indicate that Kdm3b is required for normal spermatogenesis and sexual behaviors in male mice
Title: Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors.

The following Kdm3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu13040	NM_001081256.1 Latest version!	Mus musculus KDM3B lysine (K)-specific demethylase 3B (Kdm3b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1294.30 $1849.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdm3b ( NM_001081256.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001074725.1 Mus musculus KDM3B lysine (K)-specific demethylase 3B (Kdm3b), mRNA.

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CloneID	OMu13040
Clone ID Related Accession (Same CDS sequence)	NM_001081256.1
Accession Version	NM_001081256.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5289bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	lysine-specific demethylase 3B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC114820.4. On Feb 6, 2007 this sequence version replaced XM_619530.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC151084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACG CGGCGGCCTC CCCGGTGGGC AAGCGGCTGT TGCTTCTGTT CGCGGACCCT 
ACGGCCTCAG CTTCGGCCTC GGCCCCCACG GCGGCGGCGG TAGTGAGCGG AGATCCTGGG 
CCTGCGCTGC GCACTCGGGC CTGGAGGGCC GGCACGGTGC GGGCCATGAG CGGGGCGGTG 
CCCCAGGACC TAGCGATCTT TGTGGAGTTT GACGGCTGTA ACTGGAAGCA GCACTCCTGG 
GTTAAGGTTC ACGCTGAAGA CGTGCTTGCG CTTCTGCTGG AAGGCTCACT TGTTTGGGCT 
CCCCGGAAGG ACCCCGTCCT TCTGCAGGGC ACCCGAGTCC CAGTTGCCCA GTGGCCAGCC 
CTGACTTTCA CCCCCCTAGT AGATAAGCTG GGGTTGGGGT CTGTGGTGCC AGTTGAATAC 
CTTGTGGATC GAGAGCTTCG TTTCCTGTCG GATGCTAATG GGATGCATCT GTTCCAGATG 
GGAACAGATG TTCAAAATCA GATTCTTTTA GAACATGCTG CATTAAGAGA GACAGTTAAT 
GCTTTGATCA GTGACCAAAA GCTACAAGAG ATTTTCAGCC GAGGTCCCTA TAGTGTCCAG 
GGCCACAGAG TCAAGGTCTA CCAACCCGAA GGAGAGGAAG TATGGCTCTG TGGTGTTGTG 
AGCCGTCAGG ACTCAGTCAC CCGTCTTATG GAAGTGTCTA TAACTGAGAC TGGTGAGGTC 
AAGTCAGTAG ATCCCAGACT CACCCACGTG ATGCTGATGG ACAGCTCGAC ACCACAGAGT 
GAGGGGGGTA CCATAAAAGC AGTAAAATCT TCCAAAGGAA AGAAGAAGAG AGAGAGCATA 
GAGGGGAGAG ATGGCCGGAG GAGGAAAAGT GCTTCGGACT CTGGGTGTGA CCCTGCTACA 
AAGAAATTAA AAGGAGACAG GGGTGAAGTA GACAGTAATG GGAGTGATGG AGGTGAGGCA 
AGCCGAGGGC CCTGGAAAGG AGGTAATGCC AGTGGAGAGC CAGGGCTGGA GCAGAGAGCC 
AAGCAGCCAC CGTCTACATT TGTTCCCCAG ATTAACCGCA ACATTCGCTT TGCCACTTAC 
ACCAAAGAAA ACGGCAGAAC TCTGGTGGTA CAGGATGAGC CTGTAGGTGG GGATACGCCC 
GTCCCTTTCA CTCCGTATGC TTCAGCCACA GGTCAGACAC CTTTGGCCCC AGAGGTAGGT 
GGAGCTGAAA ACAAAGAGGC GGGAAAAACG CTGGAACAAG TTAGCCAGGG CATGGTGGCT 
TCAGCAGCTG TAGTCACTAC CGCCAGCTCC ACCCCAACCA CGGTGAGGAT CTCAGACACT 
GGCCTTGCAT CAGGGACTGG GCCGGAAAAA CAGAAAGGCA GCTGGTCGCA GGCCTCAGGA 
GAGAATTCAA GAAATTCTAG TCTGGCCTCT TCTGGATTTG GAGTGTCTCT CTCAAGTTTG 
TCACAACCAT TGACTTTTGG AAGTGGACGG AGCCAGTCCA ATGGAGTTTT AGCCACAGAT 
AACAAGCCTT TGGGCTTCTC TTTCAGCTGC AGCTCTGCAT CAGAGTCTCA GAAGGACTCC 
GATCTCTCCA AGAACTTGTT TTTTCAATGC ATGTCCCAAA ATGTACCCAG CACTAACTAC 
CTGAGCAGGG TTTCAGAGAG CGTGGCCGAT GACTCCTCGA GCAGGGATTC CTTCACACAA 
AGCCTCGAGA GCCTGACTTC AGGCCTGTGT AAAGGCAGAT CTGTTCTCGG AGCAGATACT 
CAGCCAGGTC CCAAGGCCGG CAGCTCTGTG GACCGAAAAG TGCCTGCAGA GTCCATGCCC 
ACCCTTACTC CAGCCTTCCC ACGGAGTCTC CTAAATACCC GCACCCCAGA GAATCATGAA 
AATCTATTTT TACAGCCCCC GAAACTGTCC CGAGAAGAAC CTTCTAACCC TTTCCTGGCG 
TTTGTGGAGA AAGTGGAACA CAGCCCTTTC AGCAGCTTTG TGTCTCAGGC ATCAGGTAGC 
TCTTCCTCTG CTACCTCTGT CACCTCAAAG GCAACAGCCA GCTGGCCTGA GTCTCACTCC 
TCTGCAGAGT CTGCACCTTT AGCAAAGAAA AAGCCCCTCT TTATTACAAC TGACTCCTCC 
AAGCTGGTAT CTGGTGTTCT GGGCTCCGCT CTCAGCACTG GGAGTCCGAG TCTCTCTGCA 
GTGGGGAATG GCCGCTCCAG CTCGCCCACC AACAGCCTCA CCCAACCTAT TGAGATGCCT 
ACTCTCTCCT CCAGTCCCAC AGAAGAGAGG CCAACTGTGG GGCCTGGCCA GCAGGACAAT 
CCGCTCCTCA AAACCTTCAG TACCGTCTTT GGCAGGCACT CAGGCAGCTT TCTCTCCGCC 
CCAGCAGAGT TTGCACAGGA GAACAAAGCA CCTTTTGAAG CTGTAAAAAG GTTCTCATTG 
GATGAGCGAA GCTTGGCTTG CAGACAGGAT TCGGACTCCA GCACCAACAG TGACCTGTCA 
GATCTGAGCG ACTCAGAGGA GCAGCTGCAG GCCAAGAGTG GCCTGAAGGG GATTCCAGAG 
CACCTGATGG GGAAGCTAGG CCCCAACGGG GAGCGTAGTG CTGAGCTGCT ACTGGGCAAG 
GGCAAAGGGA AGCAGGCCCC AAAGGGCCGG CCCCGGACTG CTCCCCTGAA AGTTGGCCAG 
TCGGTGCTGA AGGACGTGAG TAAAGTAAGG AAGCTGAAGC AGTCTGGAGA GCCCTTCCTG 
CAGGACGGCT CCTGCATCAA CGTGGCGCCT CACTTGCACA AGTGCCGAGA GTGCCGCCTG 
GAGAGGTACC GCAAGTTTAA GGAACAGGAG CAAGATGATT CTACTGTAGC CTGCCGCTTC 
TTTCACTTCC GGAGGTTGGT CTTCACTCGA AAGGGGGTGC TCCGTGTGGA GGGATTTCTG 
AGCCCCCAGC AGAGTGACCC GGATGCCATG AACCTGTGGA TCCCCTCTTC CTCCCTAGCA 
GAAGGAATAG ACCTAGAAAC CTCAAAATAC ATCTTGGCCA ATGTTGGGGA CCAGTTCTGT 
CAGCTTGTAA TGTCTGAGAA GGAGGCCATG ATGATGGTGG AGCCACACCA GAAAGTGGCG 
TGGAAGCGAG CAGTGCGTGG AGTTCGGGAG ATGTGTGATG TGTGTGAGAC AACCCTCTTC 
AATATCCACT GGGTCTGTCG GAAATGTGGA TTTGGGGTCT GCCTTGACTG TTACCGGCTC 
AGGAAAAGCC GTCCAAGGAG TGAGACAGAA GAAATGGGGG ATGAGGAAGT TTTCTCCTGG 
CTGAAGTGTG CAAAGGGGCA GTCCCACGAA CCAGAAAACC TCATGCCCAC CCAGATCATC 
CCTGGCACAG CGCTTTACAA TATTGGAGAC ATGGTACACG CTGCCCGGGG AAAGTGGGGG 
ATTAAAGCTA ACTGCCCTTG TATAAGTCGG CAAAGCAAAT CTGTTTTGAG ACCTGCTGTC 
ACCAATGGGA TATCACAGCT TCCCAGTGTA ACCCCTAGTG CCTCTTCTGG AAACGAAACT 
ACCTTCTCAA GCGGAGGCGG AGCTGCAGCG GTCACAAATC CAGAGCCAGA CCAAGTTCCC 
AAAGGTGCTG GCACTGACGG CAGATCTGAG GAGCCCCTAA AAGCAGAAGG TTCTGCGTCA 
AATAGCAATA GTGAACTAAA AGCCATCAGG CCCCCGTGCC CGGACACAGC CCCTCCTTCC 
TCTGCTCTGC ATTGGTTGGC CGACTTAGCA ACTCAGAAGG CGAAAGAAGA AACGAAAGAT 
GCAGGGTCCC TGCGGTCGGT GCTCAATAAG GAGTCTCATT CACCCTTTGG GCTGGACTCA 
TTCAACTCTA CTGCAAAAGT CTCTCCATTG ACTCCAAAGC TTTTTAACAG CCTGTTACTG 
GGTCCCACTG CCTCCAACAG CAAAACTGAG GGTTCTAGTC TTCGAGACCT CCTTCACTCT 
GGGCCCGGAA AGCTTCCTCA AACCCCCCTG GATACAGGCA TACCCTTCCC CCCTGTTTTC 
TCTTCATCCT CAGCAGTAGC GAAGAGCAAA GCCAGCCTAC CCGACTTCCT CGACCACATC 
ATCGCCTCAG TGGTAGAAAA CAAGAAAACC TCAGATCCCT CAAAGCGGTC CTGCAACCTG 
ACCGACACCC AGAAGGAGGT GAAGGAGATG GCGATGGGGC TGAATGTGCT CGACCCCCAC 
ACGTCTCACT CCTGGCTCTG CGACGGGCGC CTTCTGTGTC TCCATGACCC CAGCAACAAA 
AATAACTGGA AGATCTTCCG AGAGTGTTGG AAACAAGGCC AGCCAGTGCT AGTTTCAGGG 
GTGCATAAAA AGCTCAAGTC TGAACTCTGG AAGCCGGAAG CCTTCAGCCA GGAGTTTGGA 
GACCAGGACG TGGACTTGGT GAACTGCAGG AATTGTGCTA TCATTTCCGA TGTTAAAGTT 
CGAGATTTCT GGGATGGCTT TGAGATCATA TGCAAGAGAC TACGGTCAGA AGATGGGCAG 
CCAATGGTGC TCAAACTCAA AGACTGGCCC CCTGGGGAAG ATTTCCGGGA CATGATGCCT 
ACAAGGTTTG AAGATCTGAT GGAGAATCTT CCTCTTCCAG AATATACCAA ACGAGATGGC 
AGGCTCAATC TGGCTTCTAG GCTACCCAGC TACTTTGTAA GGCCTGATCT GGGCCCCAAG 
ATGTACAACG CCTATGGTTT GATAACAGCA GAAGACAGAA GAGTTGGTAC AACAAATCTT 
CATTTAGATG TGTCAGACGC TGTTAATGTG ATGGTGTATG TTGGGATCCC TGTCGGGGAG 
GGTGCTCACG ATGAAGAAGT ACTCAAAACT ATTGATGAGG GAGATGCTGA TGAGGTGACC 
AAGCAGAGGA TTCATGATGG CAAAGAGAAG CCAGGAGCTT TATGGCACAT TTATGCAGCG 
AAGGATGCAG AGAAGATCCG AGAGCTGCTC CGGAAGGTTG GAGAAGAGCA AGGCCAAGAG 
AATCCTCCAG ATCATGACCC AATTCATGAC CAAAGTTGGT ATCTGGACCA GATCCTCCGA 
AAGCGACTCT TTGAAGAGTA TGGTGTGCAA GGCTGGGCCA TTGTGCAGTT CCTGGGTGAC 
GCTGTCTTCA TCCCTGCTGG AGCCCCGCAC CAGGTTCACA ATCTGTACAG TTGCATAAAG 
GTCGCAGAAG ATTTTGTATC TCCAGAGCAC GTGAAGCACT GTTTCCGCCT GACTCAGGAA 
TTCAGGCATC TCTCCAACAC TCACACCAAT CATGAGGATA AGCTACAGGT GAAGAACATC 
ATATACCACG CAGTGAAAGA CGCTGTCGGC ACTCTCAAGG CCCACGAATC CAAGCTCGCA 
AGGTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074725.1
CDS	124..5412
Translation	MADAAASPVGKRLLLLFADPTASASASAPTAAAVVSGDPGPALRTRAWRAGTVRAMSGAVPQDLAIFVEFDGCNWKQHSWVKVHAEDVLALLLEGSLVWAPRKDPVLLQGTRVPVAQWPALTFTPLVDKLGLGSVVPVEYLVDRELRFLSDANGMHLFQMGTDVQNQILLEHAALRETVNALISDQKLQEIFSRGPYSVQGHRVKVYQPEGEEVWLCGVVSRQDSVTRLMEVSITETGEVKSVDPRLTHVMLMDSSTPQSEGGTIKAVKSSKGKKKRESIEGRDGRRRKSASDSGCDPATKKLKGDRGEVDSNGSDGGEASRGPWKGGNASGEPGLEQRAKQPPSTFVPQINRNIRFATYTKENGRTLVVQDEPVGGDTPVPFTPYASATGQTPLAPEVGGAENKEAGKTLEQVSQGMVASAAVVTTASSTPTTVRISDTGLASGTGPEKQKGSWSQASGENSRNSSLASSGFGVSLSSLSQPLTFGSGRSQSNGVLATDNKPLGFSFSCSSASESQKDSDLSKNLFFQCMSQNVPSTNYLSRVSESVADDSSSRDSFTQSLESLTSGLCKGRSVLGADTQPGPKAGSSVDRKVPAESMPTLTPAFPRSLLNTRTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFVSQASGSSSSATSVTSKATASWPESHSSAESAPLAKKKPLFITTDSSKLVSGVLGSALSTGSPSLSAVGNGRSSSPTNSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSTVFGRHSGSFLSAPAEFAQENKAPFEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKSGLKGIPEHLMGKLGPNGERSAELLLGKGKGKQAPKGRPRTAPLKVGQSVLKDVSKVRKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLVFTRKGVLRVEGFLSPQQSDPDAMNLWIPSSSLAEGIDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQSKSVLRPAVTNGISQLPSVTPSASSGNETTFSSGGGAAAVTNPEPDQVPKGAGTDGRSEEPLKAEGSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETKDAGSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNSKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSSSSAVAKSKASLPDFLDHIIASVVENKKTSDPSKRSCNLTDTQKEVKEMAMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPVGEGAHDEEVLKTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQILRKRLFEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVGTLKAHESKLARS

Target ORF information:

RefSeq Version	NM_001081256.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus KDM3B lysine (K)-specific demethylase 3B (Kdm3b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001081256.1

ORF Insert Sequence:

ATGGCGGACG CGGCGGCCTC CCCGGTGGGC AAGCGGCTGT TGCTTCTGTT CGCGGACCCT 
ACGGCCTCAG CTTCGGCCTC GGCCCCCACG GCGGCGGCGG TAGTGAGCGG AGATCCTGGG 
CCTGCGCTGC GCACTCGGGC CTGGAGGGCC GGCACGGTGC GGGCCATGAG CGGGGCGGTG 
CCCCAGGACC TAGCGATCTT TGTGGAGTTT GACGGCTGTA ACTGGAAGCA GCACTCCTGG 
GTTAAGGTTC ACGCTGAAGA CGTGCTTGCG CTTCTGCTGG AAGGCTCACT TGTTTGGGCT 
CCCCGGAAGG ACCCCGTCCT TCTGCAGGGC ACCCGAGTCC CAGTTGCCCA GTGGCCAGCC 
CTGACTTTCA CCCCCCTAGT AGATAAGCTG GGGTTGGGGT CTGTGGTGCC AGTTGAATAC 
CTTGTGGATC GAGAGCTTCG TTTCCTGTCG GATGCTAATG GGATGCATCT GTTCCAGATG 
GGAACAGATG TTCAAAATCA GATTCTTTTA GAACATGCTG CATTAAGAGA GACAGTTAAT 
GCTTTGATCA GTGACCAAAA GCTACAAGAG ATTTTCAGCC GAGGTCCCTA TAGTGTCCAG 
GGCCACAGAG TCAAGGTCTA CCAACCCGAA GGAGAGGAAG TATGGCTCTG TGGTGTTGTG 
AGCCGTCAGG ACTCAGTCAC CCGTCTTATG GAAGTGTCTA TAACTGAGAC TGGTGAGGTC 
AAGTCAGTAG ATCCCAGACT CACCCACGTG ATGCTGATGG ACAGCTCGAC ACCACAGAGT 
GAGGGGGGTA CCATAAAAGC AGTAAAATCT TCCAAAGGAA AGAAGAAGAG AGAGAGCATA 
GAGGGGAGAG ATGGCCGGAG GAGGAAAAGT GCTTCGGACT CTGGGTGTGA CCCTGCTACA 
AAGAAATTAA AAGGAGACAG GGGTGAAGTA GACAGTAATG GGAGTGATGG AGGTGAGGCA 
AGCCGAGGGC CCTGGAAAGG AGGTAATGCC AGTGGAGAGC CAGGGCTGGA GCAGAGAGCC 
AAGCAGCCAC CGTCTACATT TGTTCCCCAG ATTAACCGCA ACATTCGCTT TGCCACTTAC 
ACCAAAGAAA ACGGCAGAAC TCTGGTGGTA CAGGATGAGC CTGTAGGTGG GGATACGCCC 
GTCCCTTTCA CTCCGTATGC TTCAGCCACA GGTCAGACAC CTTTGGCCCC AGAGGTAGGT 
GGAGCTGAAA ACAAAGAGGC GGGAAAAACG CTGGAACAAG TTAGCCAGGG CATGGTGGCT 
TCAGCAGCTG TAGTCACTAC CGCCAGCTCC ACCCCAACCA CGGTGAGGAT CTCAGACACT 
GGCCTTGCAT CAGGGACTGG GCCGGAAAAA CAGAAAGGCA GCTGGTCGCA GGCCTCAGGA 
GAGAATTCAA GAAATTCTAG TCTGGCCTCT TCTGGATTTG GAGTGTCTCT CTCAAGTTTG 
TCACAACCAT TGACTTTTGG AAGTGGACGG AGCCAGTCCA ATGGAGTTTT AGCCACAGAT 
AACAAGCCTT TGGGCTTCTC TTTCAGCTGC AGCTCTGCAT CAGAGTCTCA GAAGGACTCC 
GATCTCTCCA AGAACTTGTT TTTTCAATGC ATGTCCCAAA ATGTACCCAG CACTAACTAC 
CTGAGCAGGG TTTCAGAGAG CGTGGCCGAT GACTCCTCGA GCAGGGATTC CTTCACACAA 
AGCCTCGAGA GCCTGACTTC AGGCCTGTGT AAAGGCAGAT CTGTTCTCGG AGCAGATACT 
CAGCCAGGTC CCAAGGCCGG CAGCTCTGTG GACCGAAAAG TGCCTGCAGA GTCCATGCCC 
ACCCTTACTC CAGCCTTCCC ACGGAGTCTC CTAAATACCC GCACCCCAGA GAATCATGAA 
AATCTATTTT TACAGCCCCC GAAACTGTCC CGAGAAGAAC CTTCTAACCC TTTCCTGGCG 
TTTGTGGAGA AAGTGGAACA CAGCCCTTTC AGCAGCTTTG TGTCTCAGGC ATCAGGTAGC 
TCTTCCTCTG CTACCTCTGT CACCTCAAAG GCAACAGCCA GCTGGCCTGA GTCTCACTCC 
TCTGCAGAGT CTGCACCTTT AGCAAAGAAA AAGCCCCTCT TTATTACAAC TGACTCCTCC 
AAGCTGGTAT CTGGTGTTCT GGGCTCCGCT CTCAGCACTG GGAGTCCGAG TCTCTCTGCA 
GTGGGGAATG GCCGCTCCAG CTCGCCCACC AACAGCCTCA CCCAACCTAT TGAGATGCCT 
ACTCTCTCCT CCAGTCCCAC AGAAGAGAGG CCAACTGTGG GGCCTGGCCA GCAGGACAAT 
CCGCTCCTCA AAACCTTCAG TACCGTCTTT GGCAGGCACT CAGGCAGCTT TCTCTCCGCC 
CCAGCAGAGT TTGCACAGGA GAACAAAGCA CCTTTTGAAG CTGTAAAAAG GTTCTCATTG 
GATGAGCGAA GCTTGGCTTG CAGACAGGAT TCGGACTCCA GCACCAACAG TGACCTGTCA 
GATCTGAGCG ACTCAGAGGA GCAGCTGCAG GCCAAGAGTG GCCTGAAGGG GATTCCAGAG 
CACCTGATGG GGAAGCTAGG CCCCAACGGG GAGCGTAGTG CTGAGCTGCT ACTGGGCAAG 
GGCAAAGGGA AGCAGGCCCC AAAGGGCCGG CCCCGGACTG CTCCCCTGAA AGTTGGCCAG 
TCGGTGCTGA AGGACGTGAG TAAAGTAAGG AAGCTGAAGC AGTCTGGAGA GCCCTTCCTG 
CAGGACGGCT CCTGCATCAA CGTGGCGCCT CACTTGCACA AGTGCCGAGA GTGCCGCCTG 
GAGAGGTACC GCAAGTTTAA GGAACAGGAG CAAGATGATT CTACTGTAGC CTGCCGCTTC 
TTTCACTTCC GGAGGTTGGT CTTCACTCGA AAGGGGGTGC TCCGTGTGGA GGGATTTCTG 
AGCCCCCAGC AGAGTGACCC GGATGCCATG AACCTGTGGA TCCCCTCTTC CTCCCTAGCA 
GAAGGAATAG ACCTAGAAAC CTCAAAATAC ATCTTGGCCA ATGTTGGGGA CCAGTTCTGT 
CAGCTTGTAA TGTCTGAGAA GGAGGCCATG ATGATGGTGG AGCCACACCA GAAAGTGGCG 
TGGAAGCGAG CAGTGCGTGG AGTTCGGGAG ATGTGTGATG TGTGTGAGAC AACCCTCTTC 
AATATCCACT GGGTCTGTCG GAAATGTGGA TTTGGGGTCT GCCTTGACTG TTACCGGCTC 
AGGAAAAGCC GTCCAAGGAG TGAGACAGAA GAAATGGGGG ATGAGGAAGT TTTCTCCTGG 
CTGAAGTGTG CAAAGGGGCA GTCCCACGAA CCAGAAAACC TCATGCCCAC CCAGATCATC 
CCTGGCACAG CGCTTTACAA TATTGGAGAC ATGGTACACG CTGCCCGGGG AAAGTGGGGG 
ATTAAAGCTA ACTGCCCTTG TATAAGTCGG CAAAGCAAAT CTGTTTTGAG ACCTGCTGTC 
ACCAATGGGA TATCACAGCT TCCCAGTGTA ACCCCTAGTG CCTCTTCTGG AAACGAAACT 
ACCTTCTCAA GCGGAGGCGG AGCTGCAGCG GTCACAAATC CAGAGCCAGA CCAAGTTCCC 
AAAGGTGCTG GCACTGACGG CAGATCTGAG GAGCCCCTAA AAGCAGAAGG TTCTGCGTCA 
AATAGCAATA GTGAACTAAA AGCCATCAGG CCCCCGTGCC CGGACACAGC CCCTCCTTCC 
TCTGCTCTGC ATTGGTTGGC CGACTTAGCA ACTCAGAAGG CGAAAGAAGA AACGAAAGAT 
GCAGGGTCCC TGCGGTCGGT GCTCAATAAG GAGTCTCATT CACCCTTTGG GCTGGACTCA 
TTCAACTCTA CTGCAAAAGT CTCTCCATTG ACTCCAAAGC TTTTTAACAG CCTGTTACTG 
GGTCCCACTG CCTCCAACAG CAAAACTGAG GGTTCTAGTC TTCGAGACCT CCTTCACTCT 
GGGCCCGGAA AGCTTCCTCA AACCCCCCTG GATACAGGCA TACCCTTCCC CCCTGTTTTC 
TCTTCATCCT CAGCAGTAGC GAAGAGCAAA GCCAGCCTAC CCGACTTCCT CGACCACATC 
ATCGCCTCAG TGGTAGAAAA CAAGAAAACC TCAGATCCCT CAAAGCGGTC CTGCAACCTG 
ACCGACACCC AGAAGGAGGT GAAGGAGATG GCGATGGGGC TGAATGTGCT CGACCCCCAC 
ACGTCTCACT CCTGGCTCTG CGACGGGCGC CTTCTGTGTC TCCATGACCC CAGCAACAAA 
AATAACTGGA AGATCTTCCG AGAGTGTTGG AAACAAGGCC AGCCAGTGCT AGTTTCAGGG 
GTGCATAAAA AGCTCAAGTC TGAACTCTGG AAGCCGGAAG CCTTCAGCCA GGAGTTTGGA 
GACCAGGACG TGGACTTGGT GAACTGCAGG AATTGTGCTA TCATTTCCGA TGTTAAAGTT 
CGAGATTTCT GGGATGGCTT TGAGATCATA TGCAAGAGAC TACGGTCAGA AGATGGGCAG 
CCAATGGTGC TCAAACTCAA AGACTGGCCC CCTGGGGAAG ATTTCCGGGA CATGATGCCT 
ACAAGGTTTG AAGATCTGAT GGAGAATCTT CCTCTTCCAG AATATACCAA ACGAGATGGC 
AGGCTCAATC TGGCTTCTAG GCTACCCAGC TACTTTGTAA GGCCTGATCT GGGCCCCAAG 
ATGTACAACG CCTATGGTTT GATAACAGCA GAAGACAGAA GAGTTGGTAC AACAAATCTT 
CATTTAGATG TGTCAGACGC TGTTAATGTG ATGGTGTATG TTGGGATCCC TGTCGGGGAG 
GGTGCTCACG ATGAAGAAGT ACTCAAAACT ATTGATGAGG GAGATGCTGA TGAGGTGACC 
AAGCAGAGGA TTCATGATGG CAAAGAGAAG CCAGGAGCTT TATGGCACAT TTATGCAGCG 
AAGGATGCAG AGAAGATCCG AGAGCTGCTC CGGAAGGTTG GAGAAGAGCA AGGCCAAGAG 
AATCCTCCAG ATCATGACCC AATTCATGAC CAAAGTTGGT ATCTGGACCA GATCCTCCGA 
AAGCGACTCT TTGAAGAGTA TGGTGTGCAA GGCTGGGCCA TTGTGCAGTT CCTGGGTGAC 
GCTGTCTTCA TCCCTGCTGG AGCCCCGCAC CAGGTTCACA ATCTGTACAG TTGCATAAAG 
GTCGCAGAAG ATTTTGTATC TCCAGAGCAC GTGAAGCACT GTTTCCGCCT GACTCAGGAA 
TTCAGGCATC TCTCCAACAC TCACACCAAT CATGAGGATA AGCTACAGGT GAAGAACATC 
ATATACCACG CAGTGAAAGA CGCTGTCGGC ACTCTCAAGG CCCACGAATC CAAGCTCGCA 
AGGTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function.
International journal of biological sciences11(5)494-507(2015)
Liu Z,Chen X,Zhou S,Liao L,Jiang R,Xu J

Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors.
International journal of biological sciences11(12)1447-57(2015)
Liu Z,Oyola MG,Zhou S,Chen X,Liao L,Tien JC,Mani SK,Xu J

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.
Cell reports5(3)687-701(2013 Nov)
Burton A,Muller J,Tu S,Padilla-Longoria P,Guccione E,Torres-Padilla ME

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Developmental cell18(4)675-85(2010 Apr)
Guo G,Huss M,Tong GQ,Wang C,Li Sun L,Clarke ND,Robson P

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Kdm3b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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