Abcg5 cDNA ORF clone, Mus musculus(house mouse)

Inhibition of Ceramide Decreased the Expression of ATP-Binding Cassette Transporter G5/8 mRNA in an Animal Model of Cholesterol Gallstone.
Kim HJ, Kim JS, Oh S, Yoo HS
Digestive diseases (Basel, Switzerland)35(5)439-443(2017)

Evidence that the adenosine triphosphate-binding cassette G5/G8-independent pathway plays a determinant role in cholesterol gallstone formation in mice.
Wang HH, Li X, Patel SB, Wang DQ
Hepatology (Baltimore, Md.)64(3)853-64(2016 09)

Hepatic ABCG5/G8 overexpression substantially increases biliary cholesterol secretion but does not impact in?vivo macrophage-to-feces RCT.
Dikkers A, de Boer JF, Groen AK, Tietge UJ
Atherosclerosis243(2)402-6(2015 Dec)

GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice.
Wang Y, Su K, Sabeva NS, Ji A, van der Westhuyzen DR, Foufelle F, Gao X, Graf GA
Metabolism: clinical and experimental64(11)1435-43(2015 Nov)

The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.
Chase TH, Lyons BL, Bronson RT, Foreman O, Donahue LR, Burzenski LM, Gott B, Lane P, Harris B, Ceglarek U, Thiery J, Wittenburg H, Thon JN, Italiano JE Jr, Johnson KR, Shultz LD
Blood115(6)1267-76(2010 Feb)

ABCG5 and ABCG8 mRNA levels were significantly increased in cholesterol group and less increased in myriocin group, relative to that in normal group.
Title: Inhibition of Ceramide Decreased the Expression of ATP-Binding Cassette Transporter G5/8 mRNA in an Animal Model of Cholesterol Gallstone.

The ABCG5/G8-independent pathway plays an important role in regulating biliary cholesterol secretion, and gallstone formation, which works independently of the ABCG5/G8 pathway.
Title: Evidence that the adenosine triphosphate-binding cassette G5/G8-independent pathway plays a determinant role in cholesterol gallstone formation in mice.

ABCG5/G8 mediate mass biliary cholesterol secretion but not from a reverse cholesterol transport-relevant pool.
Title: Hepatic ABCG5/G8 overexpression substantially increases biliary cholesterol secretion but does not impact in?vivo macrophage-to-feces RCT.

AdGRP78 reduced expression of lipogenic genes and plasma triglycerides in the db/db strain. Both G5 and G8 protein levels increased as did total biliary cholesterol
Title: GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice.

The data demonstrate that Abcg5/Abcg8 deficiency reduces the uptake and secretion of both dietary triacylglycerols and cholesterol by the intestine, suggesting a novel role for the sterol transporter in the formation and secretion of chylomicrons.
Title: ABCG5/G8 deficiency in mice reduces dietary triacylglycerol and cholesterol transport into the lymph.