Lrrc4b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrrc4b
Entrez Gene ID	272381
Full Name	leucine rich repeat containing 4B
Synonyms	A830007M12,Lrig4
General protein information	Preferred Names leucine rich repeat containing 4B Names leucine-rich repeat-containing protein 4B NGL-3 leucine-rich repeats and immunoglobulin-like domains 4 netrin-G3 ligand
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_198250.1	NP_937893.1	leucine-rich repeat-containing protein 4B precursor

Pathways from BioSystems

Homologies

	LRRC4B	XP_001116118.1
Rattus norvegicus (Norway rat)	Lrrc4b	NP_001258010.1
Xenopus tropicalis (tropical clawed frog)	lrrc4b	NP_001096358.1
Homo sapiens (human)	LRRC4B	NP_001073926.1
Pan troglodytes (chimpanzee)	LRRC4B	XP_524348.2
Canis lupus familiaris (dog)	LRRC4B	XP_005616320.1
Bos taurus (cattle)	LRRC4B	NP_001179210.1
Mus musculus (house mouse)	Lrrc4b	NP_937893.1

Gene Ontology
Bibliography

Related articles in PubMed

NGL-3-induced presynaptic differentiation of hippocampal neurons in an afadin-dependent, nectin-1-independent manner.
Maruo T, Mandai K, Miyata M, Sakakibara S, Wang S, Sai K, Itoh Y, Kaito A, Fujiwara T, Mizoguchi A, Takai Y
Genes to cells : devoted to molecular & cellular mechanisms22(8)742-755(2017 Aug)

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.
Wentzel C, Sommer JE, Nair R, Stiefvater A, Sibarita JB, Scheiffele P
Neuron78(6)1012-23(2013 Jun)

IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase ?.
Yoshida T, Yasumura M, Uemura T, Lee SJ, Ra M, Taguchi R, Iwakura Y, Mishina M
The Journal of neuroscience : the official journal of the Society for Neuroscience31(38)13485-99(2011 Sep)

LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development.
Mandai K, Guo T, St Hillaire C, Meabon JS, Kanning KC, Bothwell M, Ginty DD
Neuron63(5)614-27(2009 Sep)

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.
Homma S, Shimada T, Hikake T, Yaginuma H
Gene expression patterns : GEP9(1)1-26(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NGL-3 induced differentiation of hippocampal mossy fibers. This activity of NGL-3 was dependent on afadin, but not the afadin-binding presynaptic nectin-1.
Title: NGL-3-induced presynaptic differentiation of hippocampal neurons in an afadin-dependent, nectin-1-independent manner.

The following Lrrc4b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrrc4b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu18034	NM_198250.1 Latest version!	Mus musculus leucine rich repeat containing 4B (Lrrc4b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrrc4b ( NM_198250.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_937893.1 Mus musculus leucine rich repeat containing 4B (Lrrc4b), mRNA.

Price & Availability↑

CloneID	OMu18034
Clone ID Related Accession (Same CDS sequence)	NM_198250.1
Accession Version	NM_198250.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Mus musculus(house mouse)
Product	leucine-rich repeat-containing protein 4B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC060263.1. On Dec 7, 2005 this sequence version replaced XM_907133.1. ##Evidence-Data-START## Transcript exon combination :: BC060263.1, CX204940.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCAGG CCCACATCCG CGGCTCCCCG TGCCCCTTGC TGCCGCCTGG TAGGATGTCC 
TGGCCCCACG GGGCTCTCTT GCTCCTGTGG CTCTTCTCCC CACCCCTGAG GGCTGGTGGG 
GGCGGTGTGG CCGTGACCTC AGCCGCTGGA GGAGGCTCCC CGCCAGCCAC CTCCTGCCCA 
GCCGCCTGCT CCTGCAGCAA CCAGGCCAGC CGGGTGATCT GCACGCGGAG GGAGCTGGCC 
GAGGTGCCAG CCAGCATCCC TGTCAACACC CGCTACCTGA ACCTGCAAGA GAACAGCATC 
CAGGTGATCC GCACGGACAC ATTCAAGCAC CTCCGGCACC TGGAGATCCT GCAGCTGAGC 
AAGAACCTGG TGCGAAAGAT CGAGGTGGGA GCGTTCAATG GGCTGCCCAG TCTCAACACA 
CTGGAACTCT TCGACAACCG GCTGACAACC GTGCCCACGC AGGCCTTTGA GTACCTGTCC 
AAGCTCCGGG AGCTGTGGCT GCGCAACAAC CCCATCGAAA GCATCCCATC CTATGCCTTC 
AACCGTGTGC CCTCACTGCG CCGCCTAGAC CTGGGCGAGC TGAAGAGGCT GGAGTACATA 
TCTGAGGCGG CCTTCGAGGG GCTGGTGAAC CTGCGCTACC TCAACCTGGG CATGTGCAAC 
CTAAAGGACA TCCCCAACCT CACAGCACTT GTGCGCCTGG AGGAGCTGGA GCTGTCCGGG 
AACCGGCTGG ACCTAATTCG CCCTGGCTCC TTCCAGGGCC TCACCAGCCT GCGCAAGCTG 
TGGCTGATGC ATGCCCAAGT GGCCACCATC GAGCGAAACG CCTTCGACGA CCTCAAGTCG 
CTGGAGGAGC TGAACCTGTC CCACAACAAC CTGATGTCGC TGCCGCACGA CCTTTTCACG 
CCCCTTCACC GCCTGGAGCG TGTCCACCTG AACCACAACC CCTGGCATTG TAACTGTGAT 
GTGCTGTGGC TCAGCTGGTG GCTGAAGGAG ACAGTGCCCA GCAATACCAC ATGCTGCGCA 
CGCTGCCACG CGCCCGCCGG CCTCAAGGGC CGCTACATTG GCGAGCTAGA CCAGTCGCAC 
TTCACCTGCT ATGCCCCGGT CATCGTGGAG CCACCCACAG ACCTCAATGT CACCGAGGGC 
ATGGCGGCTG AGCTCAAGTG CCGCACAGGC ACATCCATGA CGTCGGTCAA CTGGCTGACA 
CCTAACGGCA CGCTCATGAC GCACGGTTCC TATCGTGTGC GCATTTCAGT GCTGCACGAT 
GGCACACTCA ACTTCACCAA TGTCACCGTG CAGGACACGG GCCAGTACAC GTGCATGGTG 
ACAAACTCGG CTGGCAACAC TACTGCCTCG GCCACGCTTA ACGTGTCGGC CGTGGACCCC 
GTGGCTGCGG GAGGGCCCGG TGGCGGGGGC CCAGGGGGTG GGGGCGGTGC AGGGGGCGCG 
GGCGGATACA CCTACTTCAC CACGGTGACC GTGGAGACGC TGGAGACGCA GCCGGGGGAG 
GAGGCCCAGC AGCCCCGAGG TACTGAGAAG GAGCCCCCGG GGCCCACGAC TGATGGCGCG 
TGGGGCGGCG GCCGGCCTGA TGCTGCAGCC CCGGCCTCGG CGTCCACCAC GGCACCGGCC 
CCGCGCTCCT CGCGGCCCAC GGAGAAGGCT TTCACGGTGC CCATCACGGA CGTGACGGAG 
AATGCGCTTA AGGACCTAGA CGATGTCATG AAGACCACCA AAATCATCAT CGGCTGCTTC 
GTGGCCATCA CCTTCATGGC CGCCGTGATG CTGGTGGCCT TCTACAAGCT GCGCAAGCAG 
CACCAGCTGC ACAAGCACCA CGGGCCCACG CGCACTGTGG AGATCATCAA CGTGGAGGAC 
GAGCTGCCCG CCGCCTCCGC TGTGTCGGTG GCTGCGGCCG CCGCGGTGGC TGGAGGCGCG 
GGCGTGGGTG GGGACAGCCA CCTGGCCCTT CCGGCGCTGG AGCGAGACCA CCTCAATCAC 
CACCACTACG TTGCGGCCGC CTTCAAGGCG CACTACGGCG GCAACCCGGG AGGCGGGTGC 
GGGGCCAAAG GCCCCGGCCT CAACTCCATC CACGAACCTC TGCTCTTCAA GAGCGGCTCC 
AAGGAGAACG TGCAAGAGAC ACAAATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937893.1
CDS	81..2210
Translation	MAQAHIRGSPCPLLPPGRMSWPHGALLLLWLFSPPLRAGGGGVAVTSAAGGGSPPATSCPAACSCSNQASRVICTRRELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGPGGGGPGGGGGAGGAGGYTYFTTVTVETLETQPGEEAQQPRGTEKEPPGPTTDGAWGGGRPDAAAPASASTTAPAPRSSRPTEKAFTVPITDVTENALKDLDDVMKTTKIIIGCFVAITFMAAVMLVAFYKLRKQHQLHKHHGPTRTVEIINVEDELPAASAVSVAAAAAVAGGAGVGGDSHLALPALERDHLNHHHYVAAAFKAHYGGNPGGGCGAKGPGLNSIHEPLLFKSGSKENVQETQI

Target ORF information:

RefSeq Version	NM_198250.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus leucine rich repeat containing 4B (Lrrc4b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198250.1

ORF Insert Sequence:

ATGGCGCAGG CCCACATCCG CGGCTCCCCG TGCCCCTTGC TGCCGCCTGG TAGGATGTCC 
TGGCCCCACG GGGCTCTCTT GCTCCTGTGG CTCTTCTCCC CACCCCTGAG GGCTGGTGGG 
GGCGGTGTGG CCGTGACCTC AGCCGCTGGA GGAGGCTCCC CGCCAGCCAC CTCCTGCCCA 
GCCGCCTGCT CCTGCAGCAA CCAGGCCAGC CGGGTGATCT GCACGCGGAG GGAGCTGGCC 
GAGGTGCCAG CCAGCATCCC TGTCAACACC CGCTACCTGA ACCTGCAAGA GAACAGCATC 
CAGGTGATCC GCACGGACAC ATTCAAGCAC CTCCGGCACC TGGAGATCCT GCAGCTGAGC 
AAGAACCTGG TGCGAAAGAT CGAGGTGGGA GCGTTCAATG GGCTGCCCAG TCTCAACACA 
CTGGAACTCT TCGACAACCG GCTGACAACC GTGCCCACGC AGGCCTTTGA GTACCTGTCC 
AAGCTCCGGG AGCTGTGGCT GCGCAACAAC CCCATCGAAA GCATCCCATC CTATGCCTTC 
AACCGTGTGC CCTCACTGCG CCGCCTAGAC CTGGGCGAGC TGAAGAGGCT GGAGTACATA 
TCTGAGGCGG CCTTCGAGGG GCTGGTGAAC CTGCGCTACC TCAACCTGGG CATGTGCAAC 
CTAAAGGACA TCCCCAACCT CACAGCACTT GTGCGCCTGG AGGAGCTGGA GCTGTCCGGG 
AACCGGCTGG ACCTAATTCG CCCTGGCTCC TTCCAGGGCC TCACCAGCCT GCGCAAGCTG 
TGGCTGATGC ATGCCCAAGT GGCCACCATC GAGCGAAACG CCTTCGACGA CCTCAAGTCG 
CTGGAGGAGC TGAACCTGTC CCACAACAAC CTGATGTCGC TGCCGCACGA CCTTTTCACG 
CCCCTTCACC GCCTGGAGCG TGTCCACCTG AACCACAACC CCTGGCATTG TAACTGTGAT 
GTGCTGTGGC TCAGCTGGTG GCTGAAGGAG ACAGTGCCCA GCAATACCAC ATGCTGCGCA 
CGCTGCCACG CGCCCGCCGG CCTCAAGGGC CGCTACATTG GCGAGCTAGA CCAGTCGCAC 
TTCACCTGCT ATGCCCCGGT CATCGTGGAG CCACCCACAG ACCTCAATGT CACCGAGGGC 
ATGGCGGCTG AGCTCAAGTG CCGCACAGGC ACATCCATGA CGTCGGTCAA CTGGCTGACA 
CCTAACGGCA CGCTCATGAC GCACGGTTCC TATCGTGTGC GCATTTCAGT GCTGCACGAT 
GGCACACTCA ACTTCACCAA TGTCACCGTG CAGGACACGG GCCAGTACAC GTGCATGGTG 
ACAAACTCGG CTGGCAACAC TACTGCCTCG GCCACGCTTA ACGTGTCGGC CGTGGACCCC 
GTGGCTGCGG GAGGGCCCGG TGGCGGGGGC CCAGGGGGTG GGGGCGGTGC AGGGGGCGCG 
GGCGGATACA CCTACTTCAC CACGGTGACC GTGGAGACGC TGGAGACGCA GCCGGGGGAG 
GAGGCCCAGC AGCCCCGAGG TACTGAGAAG GAGCCCCCGG GGCCCACGAC TGATGGCGCG 
TGGGGCGGCG GCCGGCCTGA TGCTGCAGCC CCGGCCTCGG CGTCCACCAC GGCACCGGCC 
CCGCGCTCCT CGCGGCCCAC GGAGAAGGCT TTCACGGTGC CCATCACGGA CGTGACGGAG 
AATGCGCTTA AGGACCTAGA CGATGTCATG AAGACCACCA AAATCATCAT CGGCTGCTTC 
GTGGCCATCA CCTTCATGGC CGCCGTGATG CTGGTGGCCT TCTACAAGCT GCGCAAGCAG 
CACCAGCTGC ACAAGCACCA CGGGCCCACG CGCACTGTGG AGATCATCAA CGTGGAGGAC 
GAGCTGCCCG CCGCCTCCGC TGTGTCGGTG GCTGCGGCCG CCGCGGTGGC TGGAGGCGCG 
GGCGTGGGTG GGGACAGCCA CCTGGCCCTT CCGGCGCTGG AGCGAGACCA CCTCAATCAC 
CACCACTACG TTGCGGCCGC CTTCAAGGCG CACTACGGCG GCAACCCGGG AGGCGGGTGC 
GGGGCCAAAG GCCCCGGCCT CAACTCCATC CACGAACCTC TGCTCTTCAA GAGCGGCTCC 
AAGGAGAACG TGCAAGAGAC ACAAATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NGL-3-induced presynaptic differentiation of hippocampal neurons in an afadin-dependent, nectin-1-independent manner.
Genes to cells : devoted to molecular & cellular mechanisms22(8)742-755(2017 Aug)
Maruo T,Mandai K,Miyata M,Sakakibara S,Wang S,Sai K,Itoh Y,Kaito A,Fujiwara T,Mizoguchi A,Takai Y

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.
Neuron78(6)1012-23(2013 Jun)
Wentzel C,Sommer JE,Nair R,Stiefvater A,Sibarita JB,Scheiffele P

IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase ?.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(38)13485-99(2011 Sep)
Yoshida T,Yasumura M,Uemura T,Lee SJ,Ra M,Taguchi R,Iwakura Y,Mishina M

LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development.
Neuron63(5)614-27(2009 Sep)
Mandai K,Guo T,St Hillaire C,Meabon JS,Kanning KC,Bothwell M,Ginty DD

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.
Gene expression patterns : GEP9(1)1-26(2009 Jan)
Homma S,Shimada T,Hikake T,Yaginuma H

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Lrrc4b cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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