Clec4a1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clec4a1
Entrez Gene ID	269799
Full Name	C-type lectin domain family 4, member a1
Synonyms	BC049354,Dcir4
General protein information	Preferred Names C-type lectin domain family 4, member a1 Names C-type lectin domain family 4, member a1 dendritic cell inhibitory receptor 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 F2

mRNA and Protein(s)

mRNA	Protein	Name
NM_199311.2	NP_955015.1	C-type lectin domain family 4, member a1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ZNF705A	XP_003313522.1
Mus musculus (house mouse)	Clec4a1	NP_955015.1
Rattus norvegicus (Norway rat)	Clec4a1	NP_001005890.1
Homo sapiens (human)	ZNF705A	NP_001004328.1

Gene Ontology
Bibliography

Related articles in PubMed

DCIR3 and DCIR4 are co-expressed on inflammatory and patrolling monocytes.
Hsu Y, Okada R, Nishimura T, Kawasaki N, Yamamoto K, Matsumoto N
Biochemical and biophysical research communications494(3-4)440-445(2017 12)

Dendritic cell inhibitory receptor 4 (DCIR4) is preferentially expressed on inflammatory and patrolling monocytes.
Kameda Y, Hanayama M, Kishimoto A, Kume M, Yamamoto K, Matsumoto N
Biochemical and biophysical research communications480(2)215-221(2016 11)

Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex.
Flornes LM, Bryceson YT, Spurkland A, Lorentzen JC, Dissen E, Fossum S
Immunogenetics56(7)506-17(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The anti- DCIR3 antibody established in this study, together with the previously established anti-DCIR1 and anti-DCIR4 antibodies, would be a valuable tool to investigate biology and pathophysiology of monocytes.
Title: DCIR3 and DCIR4 are co-expressed on inflammatory and patrolling monocytes.

DCIR4 is preferentially expressed on the two major populations of monocytes: inflammatory and patrolling monocytes.
Title: Dendritic cell inhibitory receptor 4 (DCIR4) is preferentially expressed on inflammatory and patrolling monocytes.

The following Clec4a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clec4a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09444	NM_199311.2 Latest version!	Mus musculus C-type lectin domain family 4, member a1 (Clec4a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clec4a1 ( NM_199311.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_955015.1 Mus musculus C-type lectin domain family 4, member a1 (Clec4a1), mRNA.

Price & Availability↑

CloneID	OMu09444
Clone ID Related Accession (Same CDS sequence)	NM_199311.2
Accession Version	NM_199311.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-23
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 4, member a1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK626014.1 and BC049354.1. On Feb 23, 2011 this sequence version replaced NM_199311.1. ##Evidence-Data-START## Transcript exon combination :: BC049354.1, BQ715169.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATTAC CAAACATTTA TACTGACGTG AACTTCAAAA ATCAACCTGT TTCCTCAGGC 
CTCATCTCAG ACTCGTCTTC ATGTACCGTC TCAGACTCGT CTTCAGCTCT CCCAAAGAAG 
ACCACTATTC ACAAAAGTAA CCCTGGCTTT CCCAGGCTGC TTCTTGCCTT GTGGATATTT 
TTCCTGCTGT TGGCAATCTT ATTCTCTGTT GCTCTGATCA TTTTATTTCA AATGTATTCT 
GATCTCCTTG AAGAAAAATA TACTCTAGAA CGACTGAATC ACGCAAGATT GCATTGTGTA 
AAAAACCACT CGTCTGTAGA AGACAAAGTC TGGAGCTGTT GTCCAAAGAA TTGGAAGCCA 
TTTGATTCCC ACTGCTACTT CACTTCCCGT GACACTGCAT CCTGGAGTAA GAGTGAAGAG 
AAGTGCTCCC TCAGGGGTGC TCATCTGCTG GTGATCCAGA GCCAGGAAGA GCAGGATTTC 
ATCACCAACA CTCTGAACCC TCGTGCTGCT TATTATGTGG GGCTGTCAGA TCCAAAGGGC 
CATGGACAAT GGCAGTGGGT TGATCAGACA CCATATGATC AAAATGCCAC ATCCTGGCAC 
TCAGATGAAC CCAGTGGCAA CACTGAATTT TGTGTTGTGC TAAGTTATCA TCCAAACGTT 
AAAGGATGGG GCTGGAGTGT CGCCCCTTGT GATGGTGATC ATAGGTTGAT TTGTGAGATG 
AGGCAGCTCT ATGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_955015.1
CDS	127..864
Translation	MALPNIYTDVNFKNQPVSSGLISDSSSCTVSDSSSALPKKTTIHKSNPGFPRLLLALWIFFLLLAILFSVALIILFQMYSDLLEEKYTLERLNHARLHCVKNHSSVEDKVWSCCPKNWKPFDSHCYFTSRDTASWSKSEEKCSLRGAHLLVIQSQEEQDFITNTLNPRAAYYVGLSDPKGHGQWQWVDQTPYDQNATSWHSDEPSGNTEFCVVLSYHPNVKGWGWSVAPCDGDHRLICEMRQLYV

Target ORF information:

RefSeq Version	NM_199311.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 4, member a1 (Clec4a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199311.2

ORF Insert Sequence:

ATGGCATTAC CAAACATTTA TACTGACGTG AACTTCAAAA ATCAACCTGT TTCCTCAGGC 
CTCATCTCAG ACTCGTCTTC ATGTACCGTC TCAGACTCGT CTTCAGCTCT CCCAAAGAAG 
ACCACTATTC ACAAAAGTAA CCCTGGCTTT CCCAGGCTGC TTCTTGCCTT GTGGATATTT 
TTCCTGCTGT TGGCAATCTT ATTCTCTGTT GCTCTGATCA TTTTATTTCA AATGTATTCT 
GATCTCCTTG AAGAAAAATA TACTCTAGAA CGACTGAATC ACGCAAGATT GCATTGTGTA 
AAAAACCACT CGTCTGTAGA AGACAAAGTC TGGAGCTGTT GTCCAAAGAA TTGGAAGCCA 
TTTGATTCCC ACTGCTACTT CACTTCCCGT GACACTGCAT CCTGGAGTAA GAGTGAAGAG 
AAGTGCTCCC TCAGGGGTGC TCATCTGCTG GTGATCCAGA GCCAGGAAGA GCAGGATTTC 
ATCACCAACA CTCTGAACCC TCGTGCTGCT TATTATGTGG GGCTGTCAGA TCCAAAGGGC 
CATGGACAAT GGCAGTGGGT TGATCAGACA CCATATGATC AAAATGCCAC ATCCTGGCAC 
TCAGATGAAC CCAGTGGCAA CACTGAATTT TGTGTTGTGC TAAGTTATCA TCCAAACGTT 
AAAGGATGGG GCTGGAGTGT CGCCCCTTGT GATGGTGATC ATAGGTTGAT TTGTGAGATG 
AGGCAGCTCT ATGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DCIR3 and DCIR4 are co-expressed on inflammatory and patrolling monocytes.
Biochemical and biophysical research communications494(3-4)440-445(2017 12)
Hsu Y,Okada R,Nishimura T,Kawasaki N,Yamamoto K,Matsumoto N

Dendritic cell inhibitory receptor 4 (DCIR4) is preferentially expressed on inflammatory and patrolling monocytes.
Biochemical and biophysical research communications480(2)215-221(2016 11)
Kameda Y,Hanayama M,Kishimoto A,Kume M,Yamamoto K,Matsumoto N

Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex.
Immunogenetics56(7)506-17(2004 Oct)
Flornes LM,Bryceson YT,Spurkland A,Lorentzen JC,Dissen E,Fossum S