Snx17 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snx17
Entrez Gene ID	266781
Full Name	sorting nexin 17
Synonyms	5830447M19Rik,AI790646,D5Ertd260e,b2b1625.1Clo,mKIAA0064
General protein information	Preferred Names sorting nexin 17 Names sorting nexin-17
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 B1

mRNA and Protein(s)

mRNA	Protein	Name
XM_011240733.2	XP_011239035.1	sorting nexin-17 isoform X1
NM_153680.2	NP_710147.1	sorting nexin-17
XM_011240733.3	XP_011239035.1	sorting nexin-17 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SNX17	NP_055563.1
Canis lupus familiaris (dog)	SNX17	XP_540126.2
Bos taurus (cattle)	SNX17	NP_001015638.1
Mus musculus (house mouse)	Snx17	NP_710147.1
Caenorhabditis elegans (roundworm)	snx-17	NP_001076763.1
Pan troglodytes (chimpanzee)	SNX17	XP_515357.3
Gallus gallus (chicken)	SNX17	XP_419999.4
	SNX17	XP_001089913.2
Rattus norvegicus (Norway rat)	Snx17	NP_001011981.1
Danio rerio (zebrafish)	snx17	NP_001038622.2
Drosophila melanogaster (fruit fly)	CG5734	NP_609353.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011491	XP_317811.4
Xenopus tropicalis (tropical clawed frog)	snx17	NP_998873.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetic link between renal birth defects and congenital heart disease.
San Agustin JT, Klena N, Granath K, Panigrahy A, Stewart E, Devine W, Strittmatter L, Jonassen JA, Liu X, Lo CW, Pazour GJ
Nature communications711103(2016 Mar)

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.
Pan J, Mor G, Ju W, Zhong J, Luo X, Aldo PB, Zhong M, Yu Y, Jenkins EC, Brown WT, Zhong N
American journal of reproductive immunology (New York, N.Y. : 1989)74(3)237-57(2015 Sep)

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

Sorting nexin 17 prevents lysosomal degradation of ?1 integrins by binding to the ?1-integrin tail.
B?ttcher RT, Stremmel C, Meves A, Meyer H, Widmaier M, Tseng HY, F?ssler R
Nature cell biology14(6)584-92(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results identify SNX17 as a beta1-integrin-tail-binding protein that interacts with the free Kindlin-binding site in endosomes to stabilize beta1 integrins, resulting in their recycling to the cell surface where they can be reused
Title: Sorting nexin 17 prevents lysosomal degradation of ?1 integrins by binding to the ?1-integrin tail.

SNX17 regulates amyloid precursor protein trafficking and processing in the early endosomes
Title: Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.

results identify SNX17 as a novel adaptor protein for LDLR family members and define a novel mechanism for modulation of their endocytic activity (SNX17; sorting nexin 17)
Title: The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

The following Snx17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snx17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19943	NM_153680.2 Latest version!	Mus musculus sorting nexin 17 (Snx17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$279.30 $399.00
OMu74306	XM_011240733.3 Latest version!	Mus musculus sorting nexin 17 (Snx17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu74306	XM_011240733.2	Mus musculus sorting nexin 17 (Snx17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snx17 ( XM_011240733.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239035.1 Mus musculus sorting nexin 17 (Snx17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu74306
Clone ID Related Accession (Same CDS sequence)	XM_011240733.2 , XM_011240733.3
Accession Version	XM_011240733.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	sorting nexin-17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011240733.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAACC GGGTTGGCCT GAACCTGCTT TATGCTCAGA CGGTGTCAGA CATTGAGCAT 
GGCTGGATCC TGGTCACCAA AGAGCAGCAC CGGCAGCTCA AATCTCTGCA AGAGAAGGTC 
TCCAAAAAGG AGTTCTTGCG GCTGGCCCAA ACTCTGCGGC ACTATGGCTA TCTGCGCTTT 
GATGCCTGTG TGGCTGACTT TCCAGAGAAG GATTGCCCTG TTGTGGTGAG CGCAGGCAAC 
AGTGAGCTCA GTCTCCAGCT GCGACTACCA GGCCAGCAAC TCCGTGAAGG CTCTTTCCGT 
GTTACCCGAA TGCGATGCTG GCGGGTCACC TCCTCTGTGC CACTCCCTAG TGGGGGCACG 
AGCAGTCCAA GCCGGGGTCG GGGTGAGGTT CGCCTGGAAC TGGCTTTTGA ATACCTCATG 
AGCAAGGACC GGCTACAGTG GGTCACCATC ACCAGCCCAC AGGCTATCAT GATGAGCATC 
TGCCTGCAGT CCATGGTAGA TGAGCTGATG GTGAAGAAAT CTGGGGGCAG TATCAGGAAG 
ATGCTGCGCC GGCGGGTGGG GGGCACCCTG AGACGTTCAG ACAGCCAGCA AGCAGTGAAG 
TCCCCACCAT TGCTCGAGTC ACCAGACGCC AGCCGGGAGT CCATGGTGAA ACTCTCAAGT 
AAACTGAGTG CTGTGAGCTT GCGGGGGATT GGCAGTCCCA GCACAGATGC CAGTGCCAGT 
GCCGTCCACG GCAATTTCGC CTTCGAGGGC ATTGGAGATG AGGATCTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239035.1
CDS	745..1515
Translation	MENRVGLNLLYAQTVSDIEHGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGGTSSPSRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDASRESMVKLSSKLSAVSLRGIGSPSTDASASAVHGNFAFEGIGDEDL

Target ORF information:

RefSeq Version	XM_011240733.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sorting nexin 17 (Snx17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240733.2

ORF Insert Sequence:

ATGGAGAACC GGGTTGGCCT GAACCTGCTT TATGCTCAGA CGGTGTCAGA CATTGAGCAT 
GGCTGGATCC TGGTCACCAA AGAGCAGCAC CGGCAGCTCA AATCTCTGCA AGAGAAGGTC 
TCCAAAAAGG AGTTCTTGCG GCTGGCCCAA ACTCTGCGGC ACTATGGCTA TCTGCGCTTT 
GATGCCTGTG TGGCTGACTT TCCAGAGAAG GATTGCCCTG TTGTGGTGAG CGCAGGCAAC 
AGTGAGCTCA GTCTCCAGCT GCGACTACCA GGCCAGCAAC TCCGTGAAGG CTCTTTCCGT 
GTTACCCGAA TGCGATGCTG GCGGGTCACC TCCTCTGTGC CACTCCCTAG TGGGGGCACG 
AGCAGTCCAA GCCGGGGTCG GGGTGAGGTT CGCCTGGAAC TGGCTTTTGA ATACCTCATG 
AGCAAGGACC GGCTACAGTG GGTCACCATC ACCAGCCCAC AGGCTATCAT GATGAGCATC 
TGCCTGCAGT CCATGGTAGA TGAGCTGATG GTGAAGAAAT CTGGGGGCAG TATCAGGAAG 
ATGCTGCGCC GGCGGGTGGG GGGCACCCTG AGACGTTCAG ACAGCCAGCA AGCAGTGAAG 
TCCCCACCAT TGCTCGAGTC ACCAGACGCC AGCCGGGAGT CCATGGTGAA ACTCTCAAGT 
AAACTGAGTG CTGTGAGCTT GCGGGGGATT GGCAGTCCCA GCACAGATGC CAGTGCCAGT 
GCCGTCCACG GCAATTTCGC CTTCGAGGGC ATTGGAGATG AGGATCTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snx17 ( NM_153680.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_710147.1 Mus musculus sorting nexin 17 (Snx17), mRNA.

Price & Availability↑

CloneID	OMu19943
Clone ID Related Accession (Same CDS sequence)	NM_153680.2
Accession Version	NM_153680.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1413bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	sorting nexin-17
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC114619.9. On Nov 17, 2006 this sequence version replaced NM_153680.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC026571.1, BC023732.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCACTTTT CCATTCCTGA AACGGAGTCC CGCAGTGGGG ACAGCGGCGG CTCCGCCTAC 
GTGGCCTATA ACATTCACGT GAATGGAGTC CTGCACTGTC GGGTGCGCTA CAGCCAGCTT 
CTGGGGCTGC ACGAGCAGCT TCGGAAGGAG TATGGGGCCA ACGTGGTTCC TGCATTCCCC 
CCAAAGAAGC TGTTCTCTTT GACCCCTGCA GAGGTGGAGC AGAGGAGAGA GCAGTTGGAG 
AAGTACATGC AAGCTGTTCG GCAAGACCCA TTGCTTGGGA GCAGTGAGAC TTTTAATAGC 
TTTCTACGTC GGGCCCAACA GGAGACCCAA CAGGTGCCCA CAGAGGAGGT TTCCTTGGAA 
GTGCTGCTCA GCAATGGACA GAAAGTTCTG GTAACTGTGC TAACTTCTGA CCAGACAGAA 
GATGTCCTGG AGGCTGTGGC TGCAAAGCTG GATCTTCCAG ATGACTTGAT CGGATATTTT 
AGTCTCTTCC TTGTTCGAGA AAAAGAAGAT GGAGCCTTTT CTTTTGTACG GAAGCTGCAG 
GAGTTTGAAC TGCCTTATGT TTCTGTTACC AGTCTTCGGA GTCAAGAGTA TAAGATTGTG 
CTCAGAAAGA GTTATTGGGA CTCTGCCTAT GACGACGATG TCATGGAGAA CCGGGTTGGC 
CTGAACCTGC TTTATGCTCA GACGGTGTCA GACATTGAGC ATGGCTGGAT CCTGGTCACC 
AAAGAGCAGC ACCGGCAGCT CAAATCTCTG CAAGAGAAGG TCTCCAAAAA GGAGTTCTTG 
CGGCTGGCCC AAACTCTGCG GCACTATGGC TATCTGCGCT TTGATGCCTG TGTGGCTGAC 
TTTCCAGAGA AGGATTGCCC TGTTGTGGTG AGCGCAGGCA ACAGTGAGCT CAGTCTCCAG 
CTGCGACTAC CAGGCCAGCA ACTCCGTGAA GGCTCTTTCC GTGTTACCCG AATGCGATGC 
TGGCGGGTCA CCTCCTCTGT GCCACTCCCT AGTGGGGGCA CGAGCAGTCC AAGCCGGGGT 
CGGGGTGAGG TTCGCCTGGA ACTGGCTTTT GAATACCTCA TGAGCAAGGA CCGGCTACAG 
TGGGTCACCA TCACCAGCCC ACAGGCTATC ATGATGAGCA TCTGCCTGCA GTCCATGGTA 
GATGAGCTGA TGGTGAAGAA ATCTGGGGGC AGTATCAGGA AGATGCTGCG CCGGCGGGTG 
GGGGGCACCC TGAGACGTTC AGACAGCCAG CAAGCAGTGA AGTCCCCACC ATTGCTCGAG 
TCACCAGACG CCAGCCGGGA GTCCATGGTG AAACTCTCAA GTAAACTGAG TGCTGTGAGC 
TTGCGGGGGA TTGGCAGTCC CAGCACAGAT GCCAGTGCCA GTGCCGTCCA CGGCAATTTC 
GCCTTCGAGG GCATTGGAGA TGAGGATCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_710147.1
CDS	100..1512
Translation	MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVVPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVTVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQEFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIEHGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGGTSSPSRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDASRESMVKLSSKLSAVSLRGIGSPSTDASASAVHGNFAFEGIGDEDL

Target ORF information:

RefSeq Version	NM_153680.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus sorting nexin 17 (Snx17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153680.2

ORF Insert Sequence:

ATGCACTTTT CCATTCCTGA AACGGAGTCC CGCAGTGGGG ACAGCGGCGG CTCCGCCTAC 
GTGGCCTATA ACATTCACGT GAATGGAGTC CTGCACTGTC GGGTGCGCTA CAGCCAGCTT 
CTGGGGCTGC ACGAGCAGCT TCGGAAGGAG TATGGGGCCA ACGTGGTTCC TGCATTCCCC 
CCAAAGAAGC TGTTCTCTTT GACCCCTGCA GAGGTGGAGC AGAGGAGAGA GCAGTTGGAG 
AAGTACATGC AAGCTGTTCG GCAAGACCCA TTGCTTGGGA GCAGTGAGAC TTTTAATAGC 
TTTCTACGTC GGGCCCAACA GGAGACCCAA CAGGTGCCCA CAGAGGAGGT TTCCTTGGAA 
GTGCTGCTCA GCAATGGACA GAAAGTTCTG GTAACTGTGC TAACTTCTGA CCAGACAGAA 
GATGTCCTGG AGGCTGTGGC TGCAAAGCTG GATCTTCCAG ATGACTTGAT CGGATATTTT 
AGTCTCTTCC TTGTTCGAGA AAAAGAAGAT GGAGCCTTTT CTTTTGTACG GAAGCTGCAG 
GAGTTTGAAC TGCCTTATGT TTCTGTTACC AGTCTTCGGA GTCAAGAGTA TAAGATTGTG 
CTCAGAAAGA GTTATTGGGA CTCTGCCTAT GACGACGATG TCATGGAGAA CCGGGTTGGC 
CTGAACCTGC TTTATGCTCA GACGGTGTCA GACATTGAGC ATGGCTGGAT CCTGGTCACC 
AAAGAGCAGC ACCGGCAGCT CAAATCTCTG CAAGAGAAGG TCTCCAAAAA GGAGTTCTTG 
CGGCTGGCCC AAACTCTGCG GCACTATGGC TATCTGCGCT TTGATGCCTG TGTGGCTGAC 
TTTCCAGAGA AGGATTGCCC TGTTGTGGTG AGCGCAGGCA ACAGTGAGCT CAGTCTCCAG 
CTGCGACTAC CAGGCCAGCA ACTCCGTGAA GGCTCTTTCC GTGTTACCCG AATGCGATGC 
TGGCGGGTCA CCTCCTCTGT GCCACTCCCT AGTGGGGGCA CGAGCAGTCC AAGCCGGGGT 
CGGGGTGAGG TTCGCCTGGA ACTGGCTTTT GAATACCTCA TGAGCAAGGA CCGGCTACAG 
TGGGTCACCA TCACCAGCCC ACAGGCTATC ATGATGAGCA TCTGCCTGCA GTCCATGGTA 
GATGAGCTGA TGGTGAAGAA ATCTGGGGGC AGTATCAGGA AGATGCTGCG CCGGCGGGTG 
GGGGGCACCC TGAGACGTTC AGACAGCCAG CAAGCAGTGA AGTCCCCACC ATTGCTCGAG 
TCACCAGACG CCAGCCGGGA GTCCATGGTG AAACTCTCAA GTAAACTGAG TGCTGTGAGC 
TTGCGGGGGA TTGGCAGTCC CAGCACAGAT GCCAGTGCCA GTGCCGTCCA CGGCAATTTC 
GCCTTCGAGG GCATTGGAGA TGAGGATCTG TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snx17 ( XM_011240733.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239035.1 Mus musculus sorting nexin 17 (Snx17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu74306
Clone ID Related Accession (Same CDS sequence)	XM_011240733.2 , XM_011240733.3
Accession Version	XM_011240733.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	sorting nexin-17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011240733.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAACC GGGTTGGCCT GAACCTGCTT TATGCTCAGA CGGTGTCAGA CATTGAGCAT 
GGCTGGATCC TGGTCACCAA AGAGCAGCAC CGGCAGCTCA AATCTCTGCA AGAGAAGGTC 
TCCAAAAAGG AGTTCTTGCG GCTGGCCCAA ACTCTGCGGC ACTATGGCTA TCTGCGCTTT 
GATGCCTGTG TGGCTGACTT TCCAGAGAAG GATTGCCCTG TTGTGGTGAG CGCAGGCAAC 
AGTGAGCTCA GTCTCCAGCT GCGACTACCA GGCCAGCAAC TCCGTGAAGG CTCTTTCCGT 
GTTACCCGAA TGCGATGCTG GCGGGTCACC TCCTCTGTGC CACTCCCTAG TGGGGGCACG 
AGCAGTCCAA GCCGGGGTCG GGGTGAGGTT CGCCTGGAAC TGGCTTTTGA ATACCTCATG 
AGCAAGGACC GGCTACAGTG GGTCACCATC ACCAGCCCAC AGGCTATCAT GATGAGCATC 
TGCCTGCAGT CCATGGTAGA TGAGCTGATG GTGAAGAAAT CTGGGGGCAG TATCAGGAAG 
ATGCTGCGCC GGCGGGTGGG GGGCACCCTG AGACGTTCAG ACAGCCAGCA AGCAGTGAAG 
TCCCCACCAT TGCTCGAGTC ACCAGACGCC AGCCGGGAGT CCATGGTGAA ACTCTCAAGT 
AAACTGAGTG CTGTGAGCTT GCGGGGGATT GGCAGTCCCA GCACAGATGC CAGTGCCAGT 
GCCGTCCACG GCAATTTCGC CTTCGAGGGC ATTGGAGATG AGGATCTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239035.1
CDS	858..1628
Translation	MENRVGLNLLYAQTVSDIEHGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGGTSSPSRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDASRESMVKLSSKLSAVSLRGIGSPSTDASASAVHGNFAFEGIGDEDL

Target ORF information:

RefSeq Version	XM_011240733.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus sorting nexin 17 (Snx17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011240733.3

ORF Insert Sequence:

ATGGAGAACC GGGTTGGCCT GAACCTGCTT TATGCTCAGA CGGTGTCAGA CATTGAGCAT 
GGCTGGATCC TGGTCACCAA AGAGCAGCAC CGGCAGCTCA AATCTCTGCA AGAGAAGGTC 
TCCAAAAAGG AGTTCTTGCG GCTGGCCCAA ACTCTGCGGC ACTATGGCTA TCTGCGCTTT 
GATGCCTGTG TGGCTGACTT TCCAGAGAAG GATTGCCCTG TTGTGGTGAG CGCAGGCAAC 
AGTGAGCTCA GTCTCCAGCT GCGACTACCA GGCCAGCAAC TCCGTGAAGG CTCTTTCCGT 
GTTACCCGAA TGCGATGCTG GCGGGTCACC TCCTCTGTGC CACTCCCTAG TGGGGGCACG 
AGCAGTCCAA GCCGGGGTCG GGGTGAGGTT CGCCTGGAAC TGGCTTTTGA ATACCTCATG 
AGCAAGGACC GGCTACAGTG GGTCACCATC ACCAGCCCAC AGGCTATCAT GATGAGCATC 
TGCCTGCAGT CCATGGTAGA TGAGCTGATG GTGAAGAAAT CTGGGGGCAG TATCAGGAAG 
ATGCTGCGCC GGCGGGTGGG GGGCACCCTG AGACGTTCAG ACAGCCAGCA AGCAGTGAAG 
TCCCCACCAT TGCTCGAGTC ACCAGACGCC AGCCGGGAGT CCATGGTGAA ACTCTCAAGT 
AAACTGAGTG CTGTGAGCTT GCGGGGGATT GGCAGTCCCA GCACAGATGC CAGTGCCAGT 
GCCGTCCACG GCAATTTCGC CTTCGAGGGC ATTGGAGATG AGGATCTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic link between renal birth defects and congenital heart disease.
Nature communications711103(2016 Mar)
San Agustin JT,Klena N,Granath K,Panigrahy A,Stewart E,Devine W,Strittmatter L,Jonassen JA,Liu X,Lo CW,Pazour GJ

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.
American journal of reproductive immunology (New York, N.Y. : 1989)74(3)237-57(2015 Sep)
Pan J,Mor G,Ju W,Zhong J,Luo X,Aldo PB,Zhong M,Yu Y,Jenkins EC,Brown WT,Zhong N

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Nature521(7553)520-4(2015 May)
Li Y,Klena NT,Gabriel GC,Liu X,Kim AJ,Lemke K,Chen Y,Chatterjee B,Devine W,Damerla RR,Chang C,Yagi H,San Agustin JT,Thahir M,Anderton S,Lawhead C,Vescovi A,Pratt H,Morgan J,Haynes L,Smith CL,Eppig JT,Reinholdt L,Francis R,Leatherbury L,Ganapathiraju MK,Tobita K,Pazour GJ,Lo CW

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

Sorting nexin 17 prevents lysosomal degradation of ?1 integrins by binding to the ?1-integrin tail.
Nature cell biology14(6)584-92(2012 May)
B?ttcher RT,Stremmel C,Meves A,Meyer H,Widmaier M,Tseng HY,F?ssler R

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Snx17 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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