Psmb3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Psmb3
Entrez Gene ID	26446
Full Name	proteasome (prosome, macropain) subunit, beta type 3
Synonyms	AL033320,C10-II
General protein information	Preferred Names proteasome (prosome, macropain) subunit, beta type 3 Names proteasome subunit beta type-3 proteasome chain 13 proteasome component C10-II proteasome theta chain
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11 D\|11 61.07 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_011971.4	NP_036101.1	proteasome subunit beta type-3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Psmb3	NP_036101.1
Rattus norvegicus (Norway rat)	Psmb3	NP_058981.1
Gallus gallus (chicken)	PSMB3	XP_418119.2
Danio rerio (zebrafish)	psmb3	NP_001123295.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001697	XP_003435908.1
Eremothecium gossypii	AGOS_ABR217C	NP_983166.2
Arabidopsis thaliana (thale cress)	PBC1	NP_564149.1
Xenopus tropicalis (tropical clawed frog)	psmb3	NP_001016503.1
Homo sapiens (human)	PSMB3	NP_002786.2
Neurospora crassa	NCU03304	XP_964481.2
	PSMB3	XP_001084269.1
Canis lupus familiaris (dog)	PSMB3	NP_001239086.1
Arabidopsis thaliana (thale cress)	PBC2	NP_565156.1
Bos taurus (cattle)	PSMB3	NP_001029768.1
Drosophila melanogaster (fruit fly)	Prosbeta3	NP_649858.1
Caenorhabditis elegans (roundworm)	pbs-3	NP_494913.1
Saccharomyces cerevisiae (baker's yeast)	PUP3	NP_011020.3
Kluyveromyces lactis	KLLA0E20197g	XP_454865.1
Schizosaccharomyces pombe (fission yeast)	pup3	NP_587985.1
Magnaporthe oryzae (rice blast fungus)	MGG_04551	XP_003710932.1
Oryza sativa (rice)	Os06g0643100	NP_001058176.1

Gene Ontology
Bibliography

Related articles in PubMed

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Dai N, Zhao L, Wrighting D, Kr?mer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J
Cell metabolism21(4)609-21(2015 Apr)

PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.
Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S
Molecular and cellular biology30(15)3864-74(2010 Aug)

Mapping the murine cardiac 26S proteasome complexes.
Gomes AV, Zong C, Edmondson RD, Li X, Stefani E, Zhang J, Jones RC, Thyparambil S, Wang GW, Qiao X, Bardag-Gorce F, Ping P
Circulation research99(4)362-71(2006 Aug)

Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
McClive PJ, Hurley TM, Sarraj MA, van den Bergen JA, Sinclair AH
Genesis (New York, N.Y. : 2000)37(2)84-90(2003 Oct)

Mutagenic transgene insertion into a region of high gene density and multiple linkage disruptions on mouse chromosome 11.
Kleiter N, Artner I, Gmachl N, Ghaffari-Tabrizi N, Kratochwil K
Cytogenetic and genome research97(1-2)100-5(2002)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

located within a 185-kb contig surrounding a transgene on chromosome 11
Title: Mutagenic transgene insertion into a region of high gene density and multiple linkage disruptions on mouse chromosome 11.

The following Psmb3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psmb3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09230	NM_011971.4 Latest version!	Mus musculus proteasome (prosome, macropain) subunit, beta type 3 (Psmb3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Psmb3 ( NM_011971.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036101.1 Mus musculus proteasome (prosome, macropain) subunit, beta type 3 (Psmb3), mRNA.

Price & Availability↑

CloneID	OMu09230
Clone ID Related Accession (Same CDS sequence)	NM_011971.4
Accession Version	NM_011971.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	proteasome subunit beta type-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL596123.32. On Apr 28, 2007 this sequence version replaced NM_011971.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK153162.1, BG921975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCTATTA TGTCCTATAA TGGAGGGGCC GTCATGGCCA TGAAGGGAAA GAACTGTGTG 
GCCATCGCTG CAGACAGACG TTTCGGGATC CAGGCCCAGA TGGTGACCAC GGACTTCCAG 
AAGATCTTTC CCATGGGTGA CAGGCTCTAC ATAGGCCTGG CCGGCCTGGC CACTGACGTC 
CAGACAGTTG CCCAGCGTCT CAAGTTCCGA CTGAACTTGT ATGAGCTGAA AGAAGGTCGA 
CAGATCAAGC CTTACACCCT CATGAGCATG GTGGCCAACC TCCTGTATGA GAAGCGGTTC 
GGTCCCTACT ACACAGAGCC TGTCATTGCT GGCCTGGACC CGAAGACCTT CAAGCCCTTC 
ATTTGCTCTC TGGACCTCAT TGGCTGTCCC ATGGTGACTG ATGACTTTGT AGTCAGTGGT 
ACCTGCTCCG AACAAATGTA TGGGATGTGT GAGTCTCTCT GGGAGCCCAA CATGGATCCA 
GAACACCTGT TTGAAACCAT TTCTCAGGCC ATGCTGAACG CGGTGGACCG GGATGCCGTG 
TCGGGCATGG GCGTCATCGT CCACGTCATT GAGAAAGACA AGATCACCAC CAGGACGCTG 
AAGGCCCGGA TGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036101.1
CDS	55..672
Translation	MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHVIEKDKITTRTLKARMD

Target ORF information:

RefSeq Version	NM_011971.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus proteasome (prosome, macropain) subunit, beta type 3 (Psmb3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011971.4

ORF Insert Sequence:

ATGTCTATTA TGTCCTATAA TGGAGGGGCC GTCATGGCCA TGAAGGGAAA GAACTGTGTG 
GCCATCGCTG CAGACAGACG TTTCGGGATC CAGGCCCAGA TGGTGACCAC GGACTTCCAG 
AAGATCTTTC CCATGGGTGA CAGGCTCTAC ATAGGCCTGG CCGGCCTGGC CACTGACGTC 
CAGACAGTTG CCCAGCGTCT CAAGTTCCGA CTGAACTTGT ATGAGCTGAA AGAAGGTCGA 
CAGATCAAGC CTTACACCCT CATGAGCATG GTGGCCAACC TCCTGTATGA GAAGCGGTTC 
GGTCCCTACT ACACAGAGCC TGTCATTGCT GGCCTGGACC CGAAGACCTT CAAGCCCTTC 
ATTTGCTCTC TGGACCTCAT TGGCTGTCCC ATGGTGACTG ATGACTTTGT AGTCAGTGGT 
ACCTGCTCCG AACAAATGTA TGGGATGTGT GAGTCTCTCT GGGAGCCCAA CATGGATCCA 
GAACACCTGT TTGAAACCAT TTCTCAGGCC ATGCTGAACG CGGTGGACCG GGATGCCGTG 
TCGGGCATGG GCGTCATCGT CCACGTCATT GAGAAAGACA AGATCACCAC CAGGACGCTG 
AAGGCCCGGA TGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.
Cell metabolism21(4)609-21(2015 Apr)
Dai N,Zhao L,Wrighting D,Kr?mer D,Majithia A,Wang Y,Cracan V,Borges-Rivera D,Mootha VK,Nahrendorf M,Thorburn DR,Minichiello L,Altshuler D,Avruch J

PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.
Molecular and cellular biology30(15)3864-74(2010 Aug)
Sasaki K,Hamazaki J,Koike M,Hirano Y,Komatsu M,Uchiyama Y,Tanaka K,Murata S

Mapping the murine cardiac 26S proteasome complexes.
Circulation research99(4)362-71(2006 Aug)
Gomes AV,Zong C,Edmondson RD,Li X,Stefani E,Zhang J,Jones RC,Thyparambil S,Wang GW,Qiao X,Bardag-Gorce F,Ping P

Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
Genesis (New York, N.Y. : 2000)37(2)84-90(2003 Oct)
McClive PJ,Hurley TM,Sarraj MA,van den Bergen JA,Sinclair AH

Mutagenic transgene insertion into a region of high gene density and multiple linkage disruptions on mouse chromosome 11.
Cytogenetic and genome research97(1-2)100-5(2002)
Kleiter N,Artner I,Gmachl N,Ghaffari-Tabrizi N,Kratochwil K