Cadm4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cadm4
Entrez Gene ID	260299
Full Name	cell adhesion molecule 4
Synonyms	Igdf4c,Igsf4c,Tsll2
General protein information	Preferred Names cell adhesion molecule 4 Names cell adhesion molecule 4 NECL-4 SynCAM 4 TSLC1-like 2 TSLC1-like protein 2 immunoglobulin superfamily, member 4C membrane glycoprotein Tsll2 nectin-like protein 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 A3

mRNA and Protein(s)

mRNA	Protein	Name
NM_153112.3	NP_694752.1	cell adhesion molecule 4 precursor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	cadm4	NP_001007429.1
Pan troglodytes (chimpanzee)	CADM4	XP_512719.4
Canis lupus familiaris (dog)	CADM4	XP_541580.3
Bos taurus (cattle)	CADM4	XP_002695203.2
Rattus norvegicus (Norway rat)	Cadm4	NP_001040572.1
Homo sapiens (human)	CADM4	NP_660339.1
Mus musculus (house mouse)	Cadm4	NP_694752.1
Xenopus tropicalis (tropical clawed frog)	LOC100488420	XP_002939173.1

Gene Ontology
Bibliography

Related articles in PubMed

SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.
Suresh S, Durakoglugil D, Zhou X, Zhu B, Comerford SA, Xing C, Xie XJ, York B, O'Donnell KA
PLoS genetics13(3)e1006650(2017 Mar)

The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation.
Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y
PloS one10(4)e0124259(2015)

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y
PloS one10(3)e0121550(2015)

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, ?estan N, Gage FH, Lein ES
Development (Cambridge, England)140(22)4633-44(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Necl-4 is dispensable for axonal myelination in the developing nervous system.
Title: Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination.

findings imply that 4.1G plays a role in spermatogenesis by mediating cell-cell adhesion between spermatogenic and Sertoli cells through its interaction with NECL4 on Sertoli cells
Title: Lack of protein 4.1G causes altered expression and localization of the cell adhesion molecule nectin-like 4 in testis and can cause male infertility.

The following Cadm4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cadm4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu02318	NM_153112.3 Latest version!	Mus musculus cell adhesion molecule 4 (Cadm4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cadm4 ( NM_153112.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_694752.1 Mus musculus cell adhesion molecule 4 (Cadm4), mRNA.

Price & Availability↑

CloneID	OMu02318
Clone ID Related Accession (Same CDS sequence)	NM_153112.3
Accession Version	NM_153112.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	cell adhesion molecule 4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK143204.1. On Apr 5, 2007 this sequence version replaced NM_153112.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK143204.1, AY059394.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCGGG CCCGGCGCTT CCAGTGGCCG CTGCTGCTGC TGTGGGCGGC CGCGGCGGGG 
CCAGGGACGG GACAGGAAGT ACAGACCGAG AATGTGACTG TGGCTGAGGG TGGGGTGGCT 
GAGATCACCT GCCGTCTGCA TCAGTACGAT GGGTCCATAG TCGTCATTCA GAACCCAGCC 
CGGCAGACCC TCTTTTTCAA TGGCACCAGA GCTCTGAAGG ACGAGCGATT CCAGCTGGAG 
GAGTTCTCCC CGCGCCGGGT GCGCATCAGG CTCTCAGACG CCCGCCTGGA GGACGAGGGG 
GGTTACTTCT GCCAGCTCTA CACGGAGGAC ACCCACCATC AGATCGCCAC GCTCACTGTC 
TTAGTGGCTC CGGAGAATCC TGTGGTGGAG GTCCGAGAGC AAGCAGTGGA GGGCGGCGAG 
GTGGAACTCA GCTGCCTGGT TCCGCGGTCG CGCCCCGCAG CGGTCCTGCG CTGGTATCGG 
GATCGCAAGG AGTTGAAAGG AGTGAGCAGC GGCCAGGAGA ACGGCAAGGT GTGGAGCGTG 
GCAAGCACCG TGCGGTTCCG TGTGGATCGC AAGGACGACG GTGGTATTGT CATCTGCGAA 
GCACAGAACC AGGCGCTGCC CTCGGGACAC AGCAAGCAGA CGCAGTACGT GCTGGATGTG 
CAGTATTCCC CCACAGCGCG GATCCACGCC TCTCAAGCTG TAGTGAGGGA GGGAGACACT 
CTGGTGCTGA CCTGTGCTGT CACAGGGAAC CCCAGGCCAA ACCAGATCCG CTGGAACCGT 
GGGAATGAGT CTCTGCCAGA GAGGGCGGAG GCGGTGGGCG AGACGCTCAC GCTACCTGGC 
CTGGTATCTG CAGATAACGG CACCTACACC TGCGAGGCGG CGAACAAGCA CGGCCACGCG 
AGGGCGCTCT ACGTGCTTGT GGTCTATGAC CCCGGTGCAG TGGTAGAGGC TCAGACATCG 
GTTCCTTACG CCATTGTGGG CGGCATCCTG GCGCTACTGG TGTTTCTGAT CATATGTGTG 
CTAGTGGGCA TGGTCTGGTG CTCCGTCCGA CAGAAGGGAT CCTATCTGAC CCATGAGGCC 
AGTGGCTTGG ATGAGCAGGG AGAAGCCAGA GAAGCCTTCC TCAATGGCGG CGATGGACAC 
AAACGGAAAG AAGAATTCTT CATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_694752.1
CDS	77..1243
Translation	MGRARRFQWPLLLLWAAAAGPGTGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRSRPAAVLRWYRDRKELKGVSSGQENGKVWSVASTVRFRVDRKDDGGIVICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEAANKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLNGGDGHKRKEEFFI

Target ORF information:

RefSeq Version	NM_153112.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cell adhesion molecule 4 (Cadm4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153112.3

ORF Insert Sequence:

ATGGGCCGGG CCCGGCGCTT CCAGTGGCCG CTGCTGCTGC TGTGGGCGGC CGCGGCGGGG 
CCAGGGACGG GACAGGAAGT ACAGACCGAG AATGTGACTG TGGCTGAGGG TGGGGTGGCT 
GAGATCACCT GCCGTCTGCA TCAGTACGAT GGGTCCATAG TCGTCATTCA GAACCCAGCC 
CGGCAGACCC TCTTTTTCAA TGGCACCAGA GCTCTGAAGG ACGAGCGATT CCAGCTGGAG 
GAGTTCTCCC CGCGCCGGGT GCGCATCAGG CTCTCAGACG CCCGCCTGGA GGACGAGGGG 
GGTTACTTCT GCCAGCTCTA CACGGAGGAC ACCCACCATC AGATCGCCAC GCTCACTGTC 
TTAGTGGCTC CGGAGAATCC TGTGGTGGAG GTCCGAGAGC AAGCAGTGGA GGGCGGCGAG 
GTGGAACTCA GCTGCCTGGT TCCGCGGTCG CGCCCCGCAG CGGTCCTGCG CTGGTATCGG 
GATCGCAAGG AGTTGAAAGG AGTGAGCAGC GGCCAGGAGA ACGGCAAGGT GTGGAGCGTG 
GCAAGCACCG TGCGGTTCCG TGTGGATCGC AAGGACGACG GTGGTATTGT CATCTGCGAA 
GCACAGAACC AGGCGCTGCC CTCGGGACAC AGCAAGCAGA CGCAGTACGT GCTGGATGTG 
CAGTATTCCC CCACAGCGCG GATCCACGCC TCTCAAGCTG TAGTGAGGGA GGGAGACACT 
CTGGTGCTGA CCTGTGCTGT CACAGGGAAC CCCAGGCCAA ACCAGATCCG CTGGAACCGT 
GGGAATGAGT CTCTGCCAGA GAGGGCGGAG GCGGTGGGCG AGACGCTCAC GCTACCTGGC 
CTGGTATCTG CAGATAACGG CACCTACACC TGCGAGGCGG CGAACAAGCA CGGCCACGCG 
AGGGCGCTCT ACGTGCTTGT GGTCTATGAC CCCGGTGCAG TGGTAGAGGC TCAGACATCG 
GTTCCTTACG CCATTGTGGG CGGCATCCTG GCGCTACTGG TGTTTCTGAT CATATGTGTG 
CTAGTGGGCA TGGTCTGGTG CTCCGTCCGA CAGAAGGGAT CCTATCTGAC CCATGAGGCC 
AGTGGCTTGG ATGAGCAGGG AGAAGCCAGA GAAGCCTTCC TCAATGGCGG CGATGGACAC 
AAACGGAAAG AAGAATTCTT CATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.
PLoS genetics13(3)e1006650(2017 Mar)
Suresh S,Durakoglugil D,Zhou X,Zhu B,Comerford SA,Xing C,Xie XJ,York B,O'Donnell KA

The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation.
PloS one10(4)e0124259(2015)
Yamana S,Tokiyama A,Mizutani K,Hirata K,Takai Y,Rikitake Y

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
PloS one10(3)e0121550(2015)
Gu Z,Imai F,Kim IJ,Fujita H,Katayama Ki,Mori K,Yoshihara Y,Yoshida Y

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Development (Cambridge, England)140(22)4633-44(2013 Nov)
Miller JA,Nathanson J,Franjic D,Shim S,Dalley RA,Shapouri S,Smith KA,Sunkin SM,Bernard A,Bennett JL,Lee CK,Hawrylycz MJ,Jones AR,Amaral DG,?estan N,Gage FH,Lein ES

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Cadm4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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