Pskh1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pskh1
Entrez Gene ID	244631
Full Name	protein serine kinase H1
Synonyms	AW539964,E130013P03Rik,b2b1230Clo
General protein information	Preferred Names protein serine kinase H1 Names serine/threonine-protein kinase H1 Mutant line 1230 PSK-H1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_173432.2	NP_775608.1	serine/threonine-protein kinase H1

Pathways from BioSystems

Homologies

	PSKH1	XP_001095342.1
Canis lupus familiaris (dog)	PSKH1	XP_005620862.1
Bos taurus (cattle)	PSKH1	NP_001068881.1
Mus musculus (house mouse)	Pskh1	NP_775608.1
Gallus gallus (chicken)	PSKH1	NP_001264611.1
Danio rerio (zebrafish)	pskh1	NP_001018546.1
Homo sapiens (human)	PSKH1	NP_006733.1
Caenorhabditis elegans (roundworm)	R06A10.4	NP_490820.1
Pan troglodytes (chimpanzee)	PSKH1	XP_523507.2
Xenopus tropicalis (tropical clawed frog)	pskh1	NP_001017030.1

Gene Ontology
Bibliography

Related articles in PubMed

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Potter PK, Bowl MR, Jeyarajan P, Wisby L, Blease A, Goldsworthy ME, Simon MM, Greenaway S, Michel V, Barnard A, Aguilar C, Agnew T, Banks G, Blake A, Chessum L, Dorning J, Falcone S, Goosey L, Harris S, Haynes A, Heise I, Hillier R, Hough T, Hoslin A, Hutchison M, King R, Kumar S, Lad HV, Law G, MacLaren RE, Morse S, Nicol T, Parker A, Pickford K, Sethi S, Starbuck B, Stelma F, Cheeseman M, Cross SH, Foster RG, Jackson IJ, Peirson SN, Thakker RV, Vincent T, Scudamore C, Wells S, El-Amraoui A, Petit C, Acevedo-Arozena A, Nolan PM, Cox R, Mallon AM, Brown SD
Nature communications712444(2016 Aug)

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Burnicka-Turek O, Steimle JD, Huang W, Felker L, Kamp A, Kweon J, Peterson M, Reeves RH, Maslen CL, Gruber PJ, Yang XH, Shendure J, Moskowitz IP
Human molecular genetics25(14)3011-3028(2016 07)

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)

Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.
Keegan CE, Hutz JE, Else T, Adamska M, Shah SP, Kent AE, Howes JM, Beamer WG, Hammer GD
Human molecular genetics14(1)113-23(2005 Jan)

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes.
Paronetto MP, Giorda E, Carsetti R, Rossi P, Geremia R, Sette C
The EMBO journal23(23)4649-59(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Pskh1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pskh1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04628	NM_173432.2 Latest version!	Mus musculus protein serine kinase H1 (Pskh1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pskh1 ( NM_173432.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_775608.1 Mus musculus protein serine kinase H1 (Pskh1), mRNA.

Price & Availability↑

CloneID	OMu04628
Clone ID Related Accession (Same CDS sequence)	NM_173432.2
Accession Version	NM_173432.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1275bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	serine/threonine-protein kinase H1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC050128.1. On Jun 19, 2003 this sequence version replaced NM_173432.1. ##Evidence-Data-START## Transcript exon combination :: BC050128.1, AK166338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGCTGTG GGACAAGCAA GGTCCTTCCT GAGCCACCCA AGGATGTCCA GCTGGATCTG 
GTCAAGAAAG TGGAGCCCTT CAGTGGCACT AAGAATGATG TATACAAGCA CTTCATCACA 
GAGGTGGACA GTGTTGGCCC TCTCAAAGCT GGCTTCCCAG CTACTAGTCA GTATGCACCT 
CCCTGCCCTG GTGTTCCCAA TACTGGCCAC ACAGCGCCTC CTTCAGAACC ACCACGAAGG 
GCCAGGGTGG CAAAGTACAG GGCCAAATTT GACCCACGAG TGACAGCTAA GTATGATATA 
AAGGCCCTAA TTGGGCGAGG CAGCTTTAGC CGAGTGGTAC GTGTGGAGCA CCGGGCAACC 
CGACAGCCAT ATGCTATCAA GATGATAGAG ACCAAGTACC GAGAAGGGCG GGAGGTGTGT 
GAGTCCGAGC TCCGAGTGCT GCGCCGGGTG CGCCACGCCA ACATCATCCA GCTGGTAGAA 
GTGTTTGAGA CACAGGAGCG TGTATATATG GTGATGGAGC TGGCCACTGG CGGTGAGCTC 
TTTGACCGGA TTATTGCCAA GGGTTCTTTC ACTGAACGAG ATGCCACAAG AGTGCTTCAA 
ATGGTACTGG ATGGTGTCCG GTATCTTCAT GCCCTTGGCA TTACACACCG AGACCTCAAG 
CCTGAGAATC TCCTTTACTA CCACCCAGGC ACTGACTCCA AGATCATCAT CACTGACTTT 
GGCTTGGCCA GTGCCCGGAA GAAAGGTGAC GACTGCCTGA TGAAGACCAC GTGCGGCACA 
CCTGAGTACA TTGCTCCTGA GGTTCTGGTG CGAAAACCCT ACACCAATTC CGTGGATATG 
TGGGCACTGG GTGTCATTGC CTACATCCTG CTCAGCGGCA CCATGCCCTT TGAGGATGAC 
AACCGCACCC GGCTATACCG GCAGATCCTC AGGGGCAAAT ACAGTTATCT GGGGGAGCCC 
TGGCCTAGTG TATCTAATCT GGCCAAGGAC TTCATTGACC GCCTGCTGAC CGTGGACCCT 
GGAGCCCGGA TGACTGCACT GCAGGCCCTA AGACACCCAT GGGTAGTAAG CATGGCAGCC 
TCTTCATCCA TGAAGAATCT GCACCGATCC ATCTCCCAGA ATCTCCTCAA GCGGGCTTCC 
TCTCGTTGCC AGAGCACCAA GTCTTCCCAG TCCACGCGTT CCAGCCGCTC CACTCGTTCC 
AACAAGTCAC GCCGTGTTCG GGAGCGCGAA CTGCGGGAGC TTAACCTGCG CTATCAACAG 
CAGTATAACG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775608.1
CDS	138..1412
Translation	MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKNDVYKHFITEVDSVGPLKAGFPATSQYAPPCPGVPNTGHTAPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG

Target ORF information:

RefSeq Version	NM_173432.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein serine kinase H1 (Pskh1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173432.2

ORF Insert Sequence:

ATGGGCTGTG GGACAAGCAA GGTCCTTCCT GAGCCACCCA AGGATGTCCA GCTGGATCTG 
GTCAAGAAAG TGGAGCCCTT CAGTGGCACT AAGAATGATG TATACAAGCA CTTCATCACA 
GAGGTGGACA GTGTTGGCCC TCTCAAAGCT GGCTTCCCAG CTACTAGTCA GTATGCACCT 
CCCTGCCCTG GTGTTCCCAA TACTGGCCAC ACAGCGCCTC CTTCAGAACC ACCACGAAGG 
GCCAGGGTGG CAAAGTACAG GGCCAAATTT GACCCACGAG TGACAGCTAA GTATGATATA 
AAGGCCCTAA TTGGGCGAGG CAGCTTTAGC CGAGTGGTAC GTGTGGAGCA CCGGGCAACC 
CGACAGCCAT ATGCTATCAA GATGATAGAG ACCAAGTACC GAGAAGGGCG GGAGGTGTGT 
GAGTCCGAGC TCCGAGTGCT GCGCCGGGTG CGCCACGCCA ACATCATCCA GCTGGTAGAA 
GTGTTTGAGA CACAGGAGCG TGTATATATG GTGATGGAGC TGGCCACTGG CGGTGAGCTC 
TTTGACCGGA TTATTGCCAA GGGTTCTTTC ACTGAACGAG ATGCCACAAG AGTGCTTCAA 
ATGGTACTGG ATGGTGTCCG GTATCTTCAT GCCCTTGGCA TTACACACCG AGACCTCAAG 
CCTGAGAATC TCCTTTACTA CCACCCAGGC ACTGACTCCA AGATCATCAT CACTGACTTT 
GGCTTGGCCA GTGCCCGGAA GAAAGGTGAC GACTGCCTGA TGAAGACCAC GTGCGGCACA 
CCTGAGTACA TTGCTCCTGA GGTTCTGGTG CGAAAACCCT ACACCAATTC CGTGGATATG 
TGGGCACTGG GTGTCATTGC CTACATCCTG CTCAGCGGCA CCATGCCCTT TGAGGATGAC 
AACCGCACCC GGCTATACCG GCAGATCCTC AGGGGCAAAT ACAGTTATCT GGGGGAGCCC 
TGGCCTAGTG TATCTAATCT GGCCAAGGAC TTCATTGACC GCCTGCTGAC CGTGGACCCT 
GGAGCCCGGA TGACTGCACT GCAGGCCCTA AGACACCCAT GGGTAGTAAG CATGGCAGCC 
TCTTCATCCA TGAAGAATCT GCACCGATCC ATCTCCCAGA ATCTCCTCAA GCGGGCTTCC 
TCTCGTTGCC AGAGCACCAA GTCTTCCCAG TCCACGCGTT CCAGCCGCTC CACTCGTTCC 
AACAAGTCAC GCCGTGTTCG GGAGCGCGAA CTGCGGGAGC TTAACCTGCG CTATCAACAG 
CAGTATAACG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Nature communications712444(2016 Aug)
Potter PK,Bowl MR,Jeyarajan P,Wisby L,Blease A,Goldsworthy ME,Simon MM,Greenaway S,Michel V,Barnard A,Aguilar C,Agnew T,Banks G,Blake A,Chessum L,Dorning J,Falcone S,Goosey L,Harris S,Haynes A,Heise I,Hillier R,Hough T,Hoslin A,Hutchison M,King R,Kumar S,Lad HV,Law G,MacLaren RE,Morse S,Nicol T,Parker A,Pickford K,Sethi S,Starbuck B,Stelma F,Cheeseman M,Cross SH,Foster RG,Jackson IJ,Peirson SN,Thakker RV,Vincent T,Scudamore C,Wells S,El-Amraoui A,Petit C,Acevedo-Arozena A,Nolan PM,Cox R,Mallon AM,Brown SD

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Human molecular genetics25(14)3011-3028(2016 07)
Burnicka-Turek O,Steimle JD,Huang W,Felker L,Kamp A,Kweon J,Peterson M,Reeves RH,Maslen CL,Gruber PJ,Yang XH,Shendure J,Moskowitz IP

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Nature521(7553)520-4(2015 May)
Li Y,Klena NT,Gabriel GC,Liu X,Kim AJ,Lemke K,Chen Y,Chatterjee B,Devine W,Damerla RR,Chang C,Yagi H,San Agustin JT,Thahir M,Anderton S,Lawhead C,Vescovi A,Pratt H,Morgan J,Haynes L,Smith CL,Eppig JT,Reinholdt L,Francis R,Leatherbury L,Ganapathiraju MK,Tobita K,Pazour GJ,Lo CW

Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.
Human molecular genetics14(1)113-23(2005 Jan)
Keegan CE,Hutz JE,Else T,Adamska M,Shah SP,Kent AE,Howes JM,Beamer WG,Hammer GD

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes.
The EMBO journal23(23)4649-59(2004 Nov)
Paronetto MP,Giorda E,Carsetti R,Rossi P,Geremia R,Sette C

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Pskh1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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