Plxna4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plxna4
Entrez Gene ID	243743
Full Name	plexin A4
Synonyms	9330117B14,Plxa4,mKIAA1550
General protein information	Preferred Names plexin A4 Names plexin-A4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 A3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_175750.3	NP_786926.2	plexin-A4 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	PLXNA4	NP_065962.1
Mus musculus (house mouse)	Plxna4	NP_786926.2
Danio rerio (zebrafish)	plxna4	NP_001004495.1
	PLXNA4	XP_001099233.2
Bos taurus (cattle)	PLXNA4	NP_001178433.1
Xenopus tropicalis (tropical clawed frog)	plxna4	XP_002931894.2
Pan troglodytes (chimpanzee)	PLXNA4	XP_001136153.2
Canis lupus familiaris (dog)	PLXNA4	XP_539370.2
Rattus norvegicus (Norway rat)	Plxna4a	XP_003749761.1
Gallus gallus (chicken)	PLXNA4B	XP_425513.4

Gene Ontology
Bibliography

Related articles in PubMed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.
Pauerstein PT, Tellez K, Willmarth KB, Park KM, Hsueh B, Efsun Arda H, Gu X, Aghajanian H, Deisseroth K, Epstein JA, Kim SK
Development (Cambridge, England)144(20)3744-3754(2017 10)

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.
Gu Z, Kalambogias J, Yoshioka S, Han W, Li Z, Kawasawa YI, Pochareddy S, Li Z, Liu F, Xu X, Wijeratne HRS, Ueno M, Blatz E, Salomone J, Kumanogoh A, Rasin MR, Gebelein B, Weirauch MT, Sestan N, Martin JH, Yoshida Y
Science (New York, N.Y.)357(6349)400-404(2017 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

work reveals a 2-fold role of the PlxnA ectodomains: imposing a pre-signaling autoinhibitory separation for the cytoplasmic domains via intermolecular head-to-stalk interactions and supporting dimerization-based PlxnA activation upon ligand binding.
Title: Structural Basis for Plexin Activation and Regulation.

Both CLU and PLXNA4 have been genetically associated with Alzheimer disease (AD) risk and our data thus provide a direct relationship between two AD risk genes. Our data suggest that increasing the levels of PLXNA4 or targeting CLU-PLXNA4 interactions may have therapeutic value in AD.
Title: Identification of plexin A4 as a novel clusterin receptor links two Alzheimer's disease risk genes.

These findings suggest that by interacting with PlexA4, TrkA plays a crucial role in redirecting local Sema3A signaling to retrograde axonal transport, thereby regulating dendritic GluA2 localization and patterning.
Title: TrkA mediates retrograde semaphorin 3A signaling through plexin A4 to regulate dendritic branching.

Results suggest that semaphoring 6a activates plexin 4a by disrupting an inhibitory plexin dimer and inducing the active dimer
Title: Class A Plexins Are Organized as Preformed Inactive Dimers on the Cell Surface.

Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.
Title: Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.

The following Plxna4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plxna4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21428	NM_175750.3 Latest version!	Mus musculus plexin A4 (Plxna4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1392.30 $1989.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plxna4 ( NM_175750.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_786926.2 Mus musculus plexin A4 (Plxna4), mRNA.

Price & Availability↑

CloneID	OMu21428
Clone ID Related Accession (Same CDS sequence)	NM_175750.3
Accession Version	NM_175750.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5682bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	plexin-A4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC158678.6, AB073228.1, AC153629.3 and BF456700.1. On Apr 1, 2008 this sequence version replaced NM_175750.2. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB073228.1, BC141298.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGAAAGCCA TGCCCTGGAA CTGGACTTGC CTGCTCTCCC ACCTGCTGGT GGTAGGGATG 
GGCTCCTCCA CTCTGCTTCC ACGACAGCCA CCCCAGCTGT CTCAGAAGCC TTCCTTTGTG 
ACATTCCGAG GGGAGCCTGC TGAGGGCTTC AATCACCTTG TGGTGGATGA GAGGACAGGG 
CACATTTATT TGGGGGCTGT CAACAGAATC TACAAACTCT CTAGTGACCT CAAAGTCTTG 
GTGACTCATC AGACAGGGCC AGATGAGGAC AACCCCAAGT GTTACCCACC TCGGATTGTT 
CAGACCTGCA ATGAGCCTCT GGCCAGCACC AATAACGTCA ACAAGATGCT GCTTATAGAC 
TACAAAGAAA ACAGGCTGAT CGCGTGTGGG AGCCTGTACC AGGGTATCTG CAAGCTCCTG 
AGGCTAGAGG ACCTCTTCAA GTTGGGAGAG CCCTTTCACA AGAAGGAACA TTATCTCTCG 
GGGGTTAACG AGAGTGGCTC AGTCTTTGGG GTGATTGTTT CCTACAGCAA CTTTGATGAT 
AAACTCTTTA TTGCCACAGC AGTGGATGGC AAACCTGAAT ATTTTCCTAC CATCTCCAGC 
AGGAAGCTGA CTAAGAACTC TGAGGCCGAT GGCATGTTTG CTTACGTTTT CCATGATGAA 
TTTGTGGCCT CTATGATTAA GATCCCTTCA GACACTTTCA CGGTTATCCC CGACTTTGAC 
ATCTACTACG TCTATGGCTT CAGCAGTGGC AATTTTGTCT ACTTTTTGAC CCTTCAGCCA 
GAGATGGTGT CTCCCCCAGG CTCCACGACA AAGGAGCAGG TGTACACCTC AAAGCTTGTG 
AGGCTTTGCA AAGAGGACAC AGCCTTTAAC TCCTACGTAG AGGTGCCCAT TGGCTGTGAG 
CGCAATGGGG TGGAGTATCG CTTGTTACAG GCTGCCTACT TGTCTAAAGC TGGTGCAGTG 
CTTGGCCGGA CCCTAGGAGT CCGCCCAGAT GACGACCTCC TCTTCACCGT CTTCTCCAAG 
GGCCAGAAGC GGAAGATGAA ATCTCTGGAT GAGTCTGCCC TGTGCATCTT CATCTTGAAG 
CAGATCAATG ATCGCATTAA GGACCGCCTG CAGTCCTGTT ATAGGGGTGA GGGAACACTA 
GACCTGGCCT GGCTCAAGGT GAAGGACATC CCTTGCAGCA GTGCGCTCCT TACTATTGAT 
GACAACTTCT GTGGCCTGGA TATGAATGCT CCTCTGGGAG TTTCCGAAAT GGTGCGTGGC 
ATTCCAGTCT TCACAGAAGA CAGGGACCGC ATGACTTCTG TCATCGCCTA TGTCTACAAG 
AACCACTCAC TGGCCTTCGT GGGCACCAAA AGTGGCAAGC TGAAGAAGAT CCGGGTTGAT 
GGGCCCAAGG GAAATGCCCT CCAATATGAG ACTGTGCAGG TGGTGGACTC AGGACCAGTC 
CTCCGGGACA TGGCCTTTTC CAAGGACCAC GAGCAACTCT ACATCATGTC AGAAAGGCAG 
CTTACCAGAG TTCCTGTGGA GTCCTGTGGG CAGTACCGGA GCTGTGGCGA GTGTCTTGGC 
TCAGGTGACC CCCATTGTGG CTGGTGTGTG CTCCACAACA CGTGCACCCG GAAGGAACGG 
TGTGAACGCT CCAGAGAACC CCGAAGGTTT GCCTCAGAGA TGAAGCAGTG TGTCCGGCTG 
ACGGTCCATC CCAACAACAT CTCTGTCTCT CAGTACAACG TGCTGCTGGT CCTAGAGACA 
TACAATGTCC CGGAGCTGTC AGCAGGTGTC AACTGTACCT TTGAAGATCT GTCAGAGATG 
GATGGGCTGG TAATAGGCAA TCAGATCCAG TGCTACTCCC CTGCAGCCAA GGAAGTGCCC 
CGGATCATCA CAGAAAATGG GGACCATCAT GTTGTCCAGC TGCAACTCAA GTCAAAGGAG 
ACTGGGATGA CCTTCGCCAG CACCAGCTTT GTCTTCTACA ACTGCAGTGT CCACAATTCA 
TGCCTGTCCT GTGTGGAGAG CCCGTACCGT TGCCACTGGT GTAAATACCG GCATGTTTGT 
ACTCACGACC CCAACACATG CTCCTTCCAG GAAGGCCGAG TGAAGCTACC TGAGGACTGC 
CCCCAGCTGC TGCGAGTGGA CAAGATCCTC GTTCCAGTAG AGGTGATCAA GCCCATCACT 
CTGAAGGCTA AGAACCTCCC ACAGCCTCAG TCGGGACAGA GAGGCTACGA GTGCATCTTG 
AACATCCAGG GCATCGAGCA GAGGGTACCT GCTCTGCGCT TCAACAGCTC CAGTGTGCAG 
TGTCAGAACA CCTCCTATTC CTATGAAGGA ATGGAGATCA ACAACCTGCC AGTGGAGTTG 
ACAGTCGTGT GGAATGGACA CTTCAACATT GACAACCCAG CTCAGAATAA AGTTTACCTC 
TACAAGTGTG GAGCCATGCG CGAGAGCTGT GGGCTGTGCC TCAAGGCCGA CCCGGATTTC 
GAGTGTGGCT GGTGTCAGAG CCCAGGCCAG TGTACCCTGC GCCAGCACTG CCCTGCCCAT 
GAGAGCCGGT GGTTGGAACT GTCGGGGGCC AACAGCAAGT GCACCAACCC TCGTATCACA 
GAGATCATCC CAGTGACGGG CCCTCGAGAA GGGGGCACCA AGGTCACCAT CCGAGGGGAG 
AACTTGGGCC TGGAATTCCG TGACATTGCA TCACACGTGA AAGTGGCTGG TGTGGAATGC 
AGCCCCTTGG TGGATGGCTA CATCCCAGCT GAACAGATCG TGTGTGAGAT GGGTGAGGCC 
AAGCCTAGCC AGCATGCAGG CTTTGTGGAG ATCTGTGTGG CTGTGTGTCG GCCTGAGTTC 
ATGGCCCGCT CTTCGCAGCT CTATTACTTC ATGACTCTGA CCCTCGCAGA TCTGAAGCCC 
AACCGAGGAC CCATGTCTGG GGGGACACAG GTTACCATCA CAGGTACCAA CTTGAATGCA 
GGCAGCAATG TTGTGGTGAT GTTCGGGAGC CAGCCCTGCC TCTTCCACAG GCGCTCTCCA 
TCCTACATTA TCTGTAACAC TACATCCTCA GAGGAGGTGC TGGACATGAA GGTGACTGTG 
CAGGTGGACA GGGCCAGGAT CCGCCAGGAC CTGGTCTTTC AGTACGTGGA GGACCCCACC 
ATTGTGCGGA TTGAACCAGA ATGGAGCATT GTCAGTGGGA ACACACCTAT TGCTGTCTGG 
GGAACTCACC TGGACCTCAT ACAGAACCCA CAGATCCGTG CCAAGCATGG AGGAAAAGAA 
CACATCAACA TCTGTGAGGT CCTAAATGCT ACAGAGATGA CCTGCCAGGC TCCAGCCCTT 
GCCCTGGGTC CCGACCACCA GTCAGATCTC ACTGAGAGGC CTGAAGAATT TGGTTTCATC 
CTGGACAATG TCCAGTCTCT GCTAATTCTC AACAAGACCA ACTTCACCTA TTATCCTAAC 
CCCGTGTTTG AGGCTTTCAG TCCCTCGGGA ATCCTGGAGC TCAAGCCGGG CACCCCCATT 
ATCCTAAAGG GCAAGAACTT GATCCCGCCT GTGGCCGGAG GCAATGTGAA GCTGAACTAC 
ACCGTGCTGG TTGGGGAGAA ACCATGCACC GTGACAGTAT CAGATGTGCA GCTGCTCTGC 
GAGTCTCCCA ACCTCATCGG CAGGCACAAA GTGATGGCAC GGGTGGGTGG CATGGAGTAT 
TCCCCTGGGA TGGTATACAT CGCCCCAGAC AGCCCGCTCA GCCTGCCCGC CATTGTCAGC 
ATCGCGGTGG CTGGTGGCCT CCTCATCATC TTCATCGTGG CCGTACTCAT CGCCTACAAA 
CGCAAATCCC GAGAAAGTGA CCTCACGCTG AAGAGGTTGC AGATGCAGAT GGACAACCTT 
GAGTCCCGTG TGGCGCTGGA GTGCAAGGAA GCTTTTGCCG AGCTGCAGAC AGATATCCAT 
GAGCTTACCA GTGACCTGGA TGGAGCTGGG ATTCCCTTTC TGGACTACAG AACCTATACC 
ATGCGGGTGC TGTTCCCAGG GATTGAAGAC CACCCTGTGC TACGAGACCT TGAGGTCCCA 
GGCTACCGGC AGGAGCGTGT GGAGAAAGGA CTCAAGCTCT TCGCCCAGCT CATCAACAAC 
AAGGTGTTCC TGCTCTCTTT CATCCGCACT CTGGAGTCTC AGCGCAGTTT TTCCATGCGC 
GACCGAGGTA ACGTGGCCTC CCTCATCATG ACGGTACTTC AGAGCAAGCT AGAGTATGCC 
ACTGACGTGC TGAAGCAGCT ACTGGCTGAC CTCATTGATA AGAACCTGGA GAGCAAGAAC 
CACCCCAAGC TGCTGCTCAG GAGGACGGAG TCGGTGGCCG AGAAGATGTT GACTAATTGG 
TTCACTTTCC TCCTCTACAA GTTCCTCAAG GAGTGTGCTG GGGAGCCACT CTTCTCCCTG 
TTCTGTGCCA TCAAGCAGCA GATGGAGAAG GGCCCCATTG ATGCCATCAC CGGAGAGGCC 
CGCTACTCGC TAAGTGAGGA CAAACTCATC CGACAGCAGA TTGAATATAA AACCTTGGTC 
CTGAGCTGTG TCAGTCCAGA TAATGTTAAC AGCCCAGAGG TCCCAGTGAA GATCCTCAAC 
TGTGACACCA TCACTCAGGT CAAAGAGAAG ATCCTAGATG CCATCTTCAA GAATGTCCCG 
TGCTCCCATA GGCCCAAAGC TGCAGACATG GATCTAGAGT GGCGACAAGG AAGTGGGGCG 
AGGATGATCC TGCAGGACGA AGATATCACC ACCAAGATCG AGAATGATTG GAAGAGACTC 
AACACAGTAG CCCACTACCA GGTACCAGAT GGTTCTGTGG TGGCTTTAGT GTCCAAGCAA 
GTGACAGCCT ACAATGCAGT GAACAACTCC ACTGTCTCCA GGACTTCAGC AAGTAAATAT 
GAGAACATGA TCCGGTACAC AGGCAGCCCT GACAGCCTCC GTTCCCGGAC ACCCATGATC 
ACCCCTGACC TGGAAAGCGG GGTCAAGCTT TGGCATCTGG TGAAGAACCA TGAACATGGA 
GACCAGAAGG AGGGGGACCG GGGGAGCAAG ATGGTGTCTG AGATCTATCT GACACGACTA 
TTGGCCACAA AGGGCACACT GCAGAAGTTT GTGGATGACC TATTCGAGAC CATCTTCAGT 
ACGGCCCACC GTGGCTCCGC TCTGCCGCTA GCCATCAAGT ACATGTTTGA CTTCCTCGAT 
GAGCAGGCTG ATAAGCACGG CATCCATGAC CCGCACGTCC GCCACACCTG GAAGAGCAAC 
TGCCTGCCCC TACGGTTTTG GGTGAATATG ATCAAGAACC CTCAGTTTGT GTTTGACATC 
CATAAGAACA GCATCACGGA TGCCTGTCTC TCTGTGGTGG CCCAGACCTT CATGGACTCC 
TGCTCCACTT CGGAGCACCG ACTGGGCAAG GATTCCCCCT CCAACAAGCT GCTCTATGCC 
AAGGACATCC CCAGCTACAA GAACTGGGTA GAGAGGTATT ATTCAGACAT TGGGAAGATG 
CCGGCAATAA GTGACCAGGA CATGAATGCA TACCTGGCCG AGCAGTCGCG GATGCACATG 
AATGAGTTCA ATACGATGAG TGCGCTCTCA GAGATCTTCT CCTATGTGGG CAAATACAGT 
GAGGAGATCC TTGGACCCCT GGACCATGAT GACCAGTGTG GAAAGCAGAA ACTGGCTTAC 
AAACTAGAAC AAGTCATAAC TCTCATGAGC TTAGACAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_786926.2
CDS	975..6656
Translation	MKAMPWNWTCLLSHLLVVGMGSSTLLPRQPPQLSQKPSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHQTGPDEDNPKCYPPRIVQTCNEPLASTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPFHKKEHYLSGVNESGSVFGVIVSYSNFDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTVIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERNGVEYRLLQAAYLSKAGAVLGRTLGVRPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKDRLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPKGNALQYETVQVVDSGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYRSCGECLGSGDPHCGWCVLHNTCTRKERCERSREPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVIGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPNTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGIEQRVPALRFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVYLYKCGAMRESCGLCLKADPDFECGWCQSPGQCTLRQHCPAHESRWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLADLKPNRGPMSGGTQVTITGTNLNAGSNVVVMFGSQPCLFHRRSPSYIICNTTSSEEVLDMKVTVQVDRARIRQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYPNPVFEAFSPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLVLSCVSPDNVNSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTVAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKLWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS

Target ORF information:

RefSeq Version	NM_175750.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus plexin A4 (Plxna4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175750.3

ORF Insert Sequence:

ATGAAAGCCA TGCCCTGGAA CTGGACTTGC CTGCTCTCCC ACCTGCTGGT GGTAGGGATG 
GGCTCCTCCA CTCTGCTTCC ACGACAGCCA CCCCAGCTGT CTCAGAAGCC TTCCTTTGTG 
ACATTCCGAG GGGAGCCTGC TGAGGGCTTC AATCACCTTG TGGTGGATGA GAGGACAGGG 
CACATTTATT TGGGGGCTGT CAACAGAATC TACAAACTCT CTAGTGACCT CAAAGTCTTG 
GTGACTCATC AGACAGGGCC AGATGAGGAC AACCCCAAGT GTTACCCACC TCGGATTGTT 
CAGACCTGCA ATGAGCCTCT GGCCAGCACC AATAACGTCA ACAAGATGCT GCTTATAGAC 
TACAAAGAAA ACAGGCTGAT CGCGTGTGGG AGCCTGTACC AGGGTATCTG CAAGCTCCTG 
AGGCTAGAGG ACCTCTTCAA GTTGGGAGAG CCCTTTCACA AGAAGGAACA TTATCTCTCG 
GGGGTTAACG AGAGTGGCTC AGTCTTTGGG GTGATTGTTT CCTACAGCAA CTTTGATGAT 
AAACTCTTTA TTGCCACAGC AGTGGATGGC AAACCTGAAT ATTTTCCTAC CATCTCCAGC 
AGGAAGCTGA CTAAGAACTC TGAGGCCGAT GGCATGTTTG CTTACGTTTT CCATGATGAA 
TTTGTGGCCT CTATGATTAA GATCCCTTCA GACACTTTCA CGGTTATCCC CGACTTTGAC 
ATCTACTACG TCTATGGCTT CAGCAGTGGC AATTTTGTCT ACTTTTTGAC CCTTCAGCCA 
GAGATGGTGT CTCCCCCAGG CTCCACGACA AAGGAGCAGG TGTACACCTC AAAGCTTGTG 
AGGCTTTGCA AAGAGGACAC AGCCTTTAAC TCCTACGTAG AGGTGCCCAT TGGCTGTGAG 
CGCAATGGGG TGGAGTATCG CTTGTTACAG GCTGCCTACT TGTCTAAAGC TGGTGCAGTG 
CTTGGCCGGA CCCTAGGAGT CCGCCCAGAT GACGACCTCC TCTTCACCGT CTTCTCCAAG 
GGCCAGAAGC GGAAGATGAA ATCTCTGGAT GAGTCTGCCC TGTGCATCTT CATCTTGAAG 
CAGATCAATG ATCGCATTAA GGACCGCCTG CAGTCCTGTT ATAGGGGTGA GGGAACACTA 
GACCTGGCCT GGCTCAAGGT GAAGGACATC CCTTGCAGCA GTGCGCTCCT TACTATTGAT 
GACAACTTCT GTGGCCTGGA TATGAATGCT CCTCTGGGAG TTTCCGAAAT GGTGCGTGGC 
ATTCCAGTCT TCACAGAAGA CAGGGACCGC ATGACTTCTG TCATCGCCTA TGTCTACAAG 
AACCACTCAC TGGCCTTCGT GGGCACCAAA AGTGGCAAGC TGAAGAAGAT CCGGGTTGAT 
GGGCCCAAGG GAAATGCCCT CCAATATGAG ACTGTGCAGG TGGTGGACTC AGGACCAGTC 
CTCCGGGACA TGGCCTTTTC CAAGGACCAC GAGCAACTCT ACATCATGTC AGAAAGGCAG 
CTTACCAGAG TTCCTGTGGA GTCCTGTGGG CAGTACCGGA GCTGTGGCGA GTGTCTTGGC 
TCAGGTGACC CCCATTGTGG CTGGTGTGTG CTCCACAACA CGTGCACCCG GAAGGAACGG 
TGTGAACGCT CCAGAGAACC CCGAAGGTTT GCCTCAGAGA TGAAGCAGTG TGTCCGGCTG 
ACGGTCCATC CCAACAACAT CTCTGTCTCT CAGTACAACG TGCTGCTGGT CCTAGAGACA 
TACAATGTCC CGGAGCTGTC AGCAGGTGTC AACTGTACCT TTGAAGATCT GTCAGAGATG 
GATGGGCTGG TAATAGGCAA TCAGATCCAG TGCTACTCCC CTGCAGCCAA GGAAGTGCCC 
CGGATCATCA CAGAAAATGG GGACCATCAT GTTGTCCAGC TGCAACTCAA GTCAAAGGAG 
ACTGGGATGA CCTTCGCCAG CACCAGCTTT GTCTTCTACA ACTGCAGTGT CCACAATTCA 
TGCCTGTCCT GTGTGGAGAG CCCGTACCGT TGCCACTGGT GTAAATACCG GCATGTTTGT 
ACTCACGACC CCAACACATG CTCCTTCCAG GAAGGCCGAG TGAAGCTACC TGAGGACTGC 
CCCCAGCTGC TGCGAGTGGA CAAGATCCTC GTTCCAGTAG AGGTGATCAA GCCCATCACT 
CTGAAGGCTA AGAACCTCCC ACAGCCTCAG TCGGGACAGA GAGGCTACGA GTGCATCTTG 
AACATCCAGG GCATCGAGCA GAGGGTACCT GCTCTGCGCT TCAACAGCTC CAGTGTGCAG 
TGTCAGAACA CCTCCTATTC CTATGAAGGA ATGGAGATCA ACAACCTGCC AGTGGAGTTG 
ACAGTCGTGT GGAATGGACA CTTCAACATT GACAACCCAG CTCAGAATAA AGTTTACCTC 
TACAAGTGTG GAGCCATGCG CGAGAGCTGT GGGCTGTGCC TCAAGGCCGA CCCGGATTTC 
GAGTGTGGCT GGTGTCAGAG CCCAGGCCAG TGTACCCTGC GCCAGCACTG CCCTGCCCAT 
GAGAGCCGGT GGTTGGAACT GTCGGGGGCC AACAGCAAGT GCACCAACCC TCGTATCACA 
GAGATCATCC CAGTGACGGG CCCTCGAGAA GGGGGCACCA AGGTCACCAT CCGAGGGGAG 
AACTTGGGCC TGGAATTCCG TGACATTGCA TCACACGTGA AAGTGGCTGG TGTGGAATGC 
AGCCCCTTGG TGGATGGCTA CATCCCAGCT GAACAGATCG TGTGTGAGAT GGGTGAGGCC 
AAGCCTAGCC AGCATGCAGG CTTTGTGGAG ATCTGTGTGG CTGTGTGTCG GCCTGAGTTC 
ATGGCCCGCT CTTCGCAGCT CTATTACTTC ATGACTCTGA CCCTCGCAGA TCTGAAGCCC 
AACCGAGGAC CCATGTCTGG GGGGACACAG GTTACCATCA CAGGTACCAA CTTGAATGCA 
GGCAGCAATG TTGTGGTGAT GTTCGGGAGC CAGCCCTGCC TCTTCCACAG GCGCTCTCCA 
TCCTACATTA TCTGTAACAC TACATCCTCA GAGGAGGTGC TGGACATGAA GGTGACTGTG 
CAGGTGGACA GGGCCAGGAT CCGCCAGGAC CTGGTCTTTC AGTACGTGGA GGACCCCACC 
ATTGTGCGGA TTGAACCAGA ATGGAGCATT GTCAGTGGGA ACACACCTAT TGCTGTCTGG 
GGAACTCACC TGGACCTCAT ACAGAACCCA CAGATCCGTG CCAAGCATGG AGGAAAAGAA 
CACATCAACA TCTGTGAGGT CCTAAATGCT ACAGAGATGA CCTGCCAGGC TCCAGCCCTT 
GCCCTGGGTC CCGACCACCA GTCAGATCTC ACTGAGAGGC CTGAAGAATT TGGTTTCATC 
CTGGACAATG TCCAGTCTCT GCTAATTCTC AACAAGACCA ACTTCACCTA TTATCCTAAC 
CCCGTGTTTG AGGCTTTCAG TCCCTCGGGA ATCCTGGAGC TCAAGCCGGG CACCCCCATT 
ATCCTAAAGG GCAAGAACTT GATCCCGCCT GTGGCCGGAG GCAATGTGAA GCTGAACTAC 
ACCGTGCTGG TTGGGGAGAA ACCATGCACC GTGACAGTAT CAGATGTGCA GCTGCTCTGC 
GAGTCTCCCA ACCTCATCGG CAGGCACAAA GTGATGGCAC GGGTGGGTGG CATGGAGTAT 
TCCCCTGGGA TGGTATACAT CGCCCCAGAC AGCCCGCTCA GCCTGCCCGC CATTGTCAGC 
ATCGCGGTGG CTGGTGGCCT CCTCATCATC TTCATCGTGG CCGTACTCAT CGCCTACAAA 
CGCAAATCCC GAGAAAGTGA CCTCACGCTG AAGAGGTTGC AGATGCAGAT GGACAACCTT 
GAGTCCCGTG TGGCGCTGGA GTGCAAGGAA GCTTTTGCCG AGCTGCAGAC AGATATCCAT 
GAGCTTACCA GTGACCTGGA TGGAGCTGGG ATTCCCTTTC TGGACTACAG AACCTATACC 
ATGCGGGTGC TGTTCCCAGG GATTGAAGAC CACCCTGTGC TACGAGACCT TGAGGTCCCA 
GGCTACCGGC AGGAGCGTGT GGAGAAAGGA CTCAAGCTCT TCGCCCAGCT CATCAACAAC 
AAGGTGTTCC TGCTCTCTTT CATCCGCACT CTGGAGTCTC AGCGCAGTTT TTCCATGCGC 
GACCGAGGTA ACGTGGCCTC CCTCATCATG ACGGTACTTC AGAGCAAGCT AGAGTATGCC 
ACTGACGTGC TGAAGCAGCT ACTGGCTGAC CTCATTGATA AGAACCTGGA GAGCAAGAAC 
CACCCCAAGC TGCTGCTCAG GAGGACGGAG TCGGTGGCCG AGAAGATGTT GACTAATTGG 
TTCACTTTCC TCCTCTACAA GTTCCTCAAG GAGTGTGCTG GGGAGCCACT CTTCTCCCTG 
TTCTGTGCCA TCAAGCAGCA GATGGAGAAG GGCCCCATTG ATGCCATCAC CGGAGAGGCC 
CGCTACTCGC TAAGTGAGGA CAAACTCATC CGACAGCAGA TTGAATATAA AACCTTGGTC 
CTGAGCTGTG TCAGTCCAGA TAATGTTAAC AGCCCAGAGG TCCCAGTGAA GATCCTCAAC 
TGTGACACCA TCACTCAGGT CAAAGAGAAG ATCCTAGATG CCATCTTCAA GAATGTCCCG 
TGCTCCCATA GGCCCAAAGC TGCAGACATG GATCTAGAGT GGCGACAAGG AAGTGGGGCG 
AGGATGATCC TGCAGGACGA AGATATCACC ACCAAGATCG AGAATGATTG GAAGAGACTC 
AACACAGTAG CCCACTACCA GGTACCAGAT GGTTCTGTGG TGGCTTTAGT GTCCAAGCAA 
GTGACAGCCT ACAATGCAGT GAACAACTCC ACTGTCTCCA GGACTTCAGC AAGTAAATAT 
GAGAACATGA TCCGGTACAC AGGCAGCCCT GACAGCCTCC GTTCCCGGAC ACCCATGATC 
ACCCCTGACC TGGAAAGCGG GGTCAAGCTT TGGCATCTGG TGAAGAACCA TGAACATGGA 
GACCAGAAGG AGGGGGACCG GGGGAGCAAG ATGGTGTCTG AGATCTATCT GACACGACTA 
TTGGCCACAA AGGGCACACT GCAGAAGTTT GTGGATGACC TATTCGAGAC CATCTTCAGT 
ACGGCCCACC GTGGCTCCGC TCTGCCGCTA GCCATCAAGT ACATGTTTGA CTTCCTCGAT 
GAGCAGGCTG ATAAGCACGG CATCCATGAC CCGCACGTCC GCCACACCTG GAAGAGCAAC 
TGCCTGCCCC TACGGTTTTG GGTGAATATG ATCAAGAACC CTCAGTTTGT GTTTGACATC 
CATAAGAACA GCATCACGGA TGCCTGTCTC TCTGTGGTGG CCCAGACCTT CATGGACTCC 
TGCTCCACTT CGGAGCACCG ACTGGGCAAG GATTCCCCCT CCAACAAGCT GCTCTATGCC 
AAGGACATCC CCAGCTACAA GAACTGGGTA GAGAGGTATT ATTCAGACAT TGGGAAGATG 
CCGGCAATAA GTGACCAGGA CATGAATGCA TACCTGGCCG AGCAGTCGCG GATGCACATG 
AATGAGTTCA ATACGATGAG TGCGCTCTCA GAGATCTTCT CCTATGTGGG CAAATACAGT 
GAGGAGATCC TTGGACCCCT GGACCATGAT GACCAGTGTG GAAAGCAGAA ACTGGCTTAC 
AAACTAGAAC AAGTCATAAC TCTCATGAGC TTAGACAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.
Development (Cambridge, England)144(20)3744-3754(2017 10)
Pauerstein PT,Tellez K,Willmarth KB,Park KM,Hsueh B,Efsun Arda H,Gu X,Aghajanian H,Deisseroth K,Epstein JA,Kim SK

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.
Science (New York, N.Y.)357(6349)400-404(2017 07)
Gu Z,Kalambogias J,Yoshioka S,Han W,Li Z,Kawasawa YI,Pochareddy S,Li Z,Liu F,Xu X,Wijeratne HRS,Ueno M,Blatz E,Salomone J,Kumanogoh A,Rasin MR,Gebelein B,Weirauch MT,Sestan N,Martin JH,Yoshida Y

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Plxna4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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