Pde11a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pde11a
Entrez Gene ID	241489
Full Name	phosphodiesterase 11A
Synonyms	6330414F14Rik,A630086N24Rik,Gm350,PDE11A1
General protein information	Preferred Names phosphodiesterase 11A Names dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A cAMP and cGMP phosphodiesterase 11A
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001081033.2	NP_001074502.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
XM_006499453.2	XP_006499516.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1
XM_006499454.2	XP_006499517.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X2
NM_001081033.1	NP_001074502.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
NM_001081033.3	NP_001074502.1	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PDE11A	XP_005640467.1
	PDE11A	XP_001097592.1
Danio rerio (zebrafish)	pde11a	XP_689838.4
Drosophila melanogaster (fruit fly)	Pde6	NP_650369.3
Homo sapiens (human)	PDE11A	NP_058649.3
Gallus gallus (chicken)	PDE11A	XP_421985.4
Bos taurus (cattle)	PDE11A	NP_001192351.1
Mus musculus (house mouse)	Pde11a	NP_001074502.1
Rattus norvegicus (Norway rat)	Pde11a	NP_543169.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004119	XP_312997.5
Xenopus tropicalis (tropical clawed frog)	pde11a	XP_002934646.1

Gene Ontology
Bibliography

Related articles in PubMed

PDE11A negatively regulates lithium responsivity.
Pathak G, Agostino MJ, Bishara K, Capell WR, Fisher JL, Hegde S, Ibrahim BA, Pilarzyk K, Sabin C, Tuczkewycz T, Wilson S, Kelly MP
Molecular psychiatry22(12)1714-1724(2017 Dec)

Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity.
Paul A, Crow M, Raudales R, He M, Gillis J, Huang ZJ
Cell171(3)522-539.e20(2017 Oct)

Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice.
Hegde S, Capell WR, Ibrahim BA, Klett J, Patel NS, Sougiannis AT, Kelly MP
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology41(12)2920-2931(2016 Nov)

PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain.
Hegde S, Ji H, Oliver D, Patel NS, Poupore N, Shtutman M, Kelly MP
Neuroscience335151-69(2016 Oct)

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A, Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR
Neuron83(2)309-323(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data of this study suggest PDE11A is selectively required for the proper consolidation of recognition and associative social memories.
Title: Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice.

PDE11A is a key regulator of the oxytocin pathway and membrane signaling, consistent with its pivotal role in regulating social behavior
Title: PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain.

PDE11A knockout mice show subtle psychiatric-disease-related deficits, including hyperactivity in an open field, increased sensitivity to the glutamate N-methyl-D-aspartate receptor antagonist MK-801, as well as deficits in social behaviors
Title: Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes.

The following Pde11a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pde11a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu30435	XM_006499454.2 Latest version!	Mus musculus phosphodiesterase 11A (Pde11a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu01562	NM_001081033.3 Latest version!	Mus musculus phosphodiesterase 11A (Pde11a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OMu30434	XM_006499453.2 Latest version!	Mus musculus phosphodiesterase 11A (Pde11a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OMu01562	NM_001081033.1	Mus musculus phosphodiesterase 11A (Pde11a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$545.30 $779.00
OMu01562	NM_001081033.2	Mus musculus phosphodiesterase 11A (Pde11a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$545.30 $779.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pde11a ( XM_006499454.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499517.1 Mus musculus phosphodiesterase 11A (Pde11a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu30435
Clone ID Related Accession (Same CDS sequence)	XM_006499454.2
Accession Version	XM_006499454.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2943bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006499454.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGTGCTG TCGTACCACG CCACGTGTTC CAAGGCTGAA 
GTCGACAAGT TTAAGGCAGC CAACATCCCT CTGGTGTCGG AACTGGCCAT CGATGACATC 
CATTTCGATG ACTTTTCCCT TGATGTTGAT GCCATGATCA CAGCCGCTCT ACGGATGTTC 
ATGGAGCTGG GGATGGTACA GAAATTTAAA ATCGACTATG AGACCCTGTG CAGGTGGCTT 
CTGACGGTAA GGAAAAACTA TCGGATGGTT CTCTACCACA ACTGGAGACA TGCCTTCAAC 
GTGTGCCAAC TGATGTTTGC CATGCTAACT ACTGCTGGGT TCCAAGAGAT TCTGACCGAG 
GTGGAAATTT TAGCGGTGAT TGTGGGATGC CTGTGTCATG ACCTCGACCA CAGGGGAACC 
AACAATGCCT TCCAAGCTAA GAGTGACTCT GCACTGGCCC AGCTCTACGG GACCTCGGCG 
ACCTTGGAGC ATCACCATTT TAACCATGCT GTGATGATCC TTCAGAGTGA GGGTCACAAC 
ATCTTTGCTA ATTTGTCCTC CAAGGAATAC AGTGACCTCA TGCAGCTCCT GAAGCAGTCA 
ATATTAGCCA CAGACCTCAC GCTCTACTTT GAGAGAAGAA CTGAGTTCTT CGAGCTTGTC 
AGGAAAGGAG ACTACGATTG GAGCATCACA AGCCACCGAG ATGTGTTCCG ATCAATGTTA 
ATGACAGCCT GTGACCTTGG AGCCGTGACC AAACCGTGGG AGATCTCCAG ACAGGTGGCT 
GAACTTGTAA CCAGCGAGTT CTTTGAACAA GGAGATCGGG AGAGGTCGGA ACTCAAGCTC 
ACTCCCTCTG CTATTTTTGA CCGGAACCGG AAAGATGAAC TGCCTCGGTT GCAGCTGGAG 
TGGATTGATA GCATCTGCAT GCCTTTGTAT CAGAGCATCG GCAGCAACAT CCGTGGTCCT 
GAGTTTCTCA CAGAAAGCAC AGAGCTTGCA TTCTTTGTCT ACTTGAATGA GTCCCTGACA 
ACTGGTGGCT GGGAAGGGGA TAGTCTACTT CTGTTCTTTG CAGGCCTTGG TGAAGGTCAA 
TGCAAAACTG AAACCAATGC TGGATTCAGT GGCTGCCAAC CGAAGGAAGT GGGAAGAGTT 
GCACCAAAAA AGACTACAGG TCTCGGCTGC CTCCCCAGAC CCTGCCAGTC CCATGGTGGC 
CGGGGAAGAC AGACTGTAAA CCACCCAGAG CCGCTGCGCC ACCCTGTGGT CGGGAGGGTC 
CTCCGCATCC TGAACTACTT GCTTTGGTTG AACCGCAACA TCCTATTGGT TCAGCTCGGA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499517.1
CDS	539..3481
Translation	MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASSLAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQSIGSNIRGPEFLTESTELAFFVYLNESLTTGGWEGDSLLLFFAGLGEGQCKTETNAGFSGCQPKEVGRVAPKKTTGLGCLPRPCQSHGGRGRQTVNHPEPLRHPVVGRVLRILNYLLWLNRNILLVQLG

Target ORF information:

RefSeq Version	XM_006499454.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphodiesterase 11A (Pde11a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499454.2

ORF Insert Sequence:

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGTGCTG TCGTACCACG CCACGTGTTC CAAGGCTGAA 
GTCGACAAGT TTAAGGCAGC CAACATCCCT CTGGTGTCGG AACTGGCCAT CGATGACATC 
CATTTCGATG ACTTTTCCCT TGATGTTGAT GCCATGATCA CAGCCGCTCT ACGGATGTTC 
ATGGAGCTGG GGATGGTACA GAAATTTAAA ATCGACTATG AGACCCTGTG CAGGTGGCTT 
CTGACGGTAA GGAAAAACTA TCGGATGGTT CTCTACCACA ACTGGAGACA TGCCTTCAAC 
GTGTGCCAAC TGATGTTTGC CATGCTAACT ACTGCTGGGT TCCAAGAGAT TCTGACCGAG 
GTGGAAATTT TAGCGGTGAT TGTGGGATGC CTGTGTCATG ACCTCGACCA CAGGGGAACC 
AACAATGCCT TCCAAGCTAA GAGTGACTCT GCACTGGCCC AGCTCTACGG GACCTCGGCG 
ACCTTGGAGC ATCACCATTT TAACCATGCT GTGATGATCC TTCAGAGTGA GGGTCACAAC 
ATCTTTGCTA ATTTGTCCTC CAAGGAATAC AGTGACCTCA TGCAGCTCCT GAAGCAGTCA 
ATATTAGCCA CAGACCTCAC GCTCTACTTT GAGAGAAGAA CTGAGTTCTT CGAGCTTGTC 
AGGAAAGGAG ACTACGATTG GAGCATCACA AGCCACCGAG ATGTGTTCCG ATCAATGTTA 
ATGACAGCCT GTGACCTTGG AGCCGTGACC AAACCGTGGG AGATCTCCAG ACAGGTGGCT 
GAACTTGTAA CCAGCGAGTT CTTTGAACAA GGAGATCGGG AGAGGTCGGA ACTCAAGCTC 
ACTCCCTCTG CTATTTTTGA CCGGAACCGG AAAGATGAAC TGCCTCGGTT GCAGCTGGAG 
TGGATTGATA GCATCTGCAT GCCTTTGTAT CAGAGCATCG GCAGCAACAT CCGTGGTCCT 
GAGTTTCTCA CAGAAAGCAC AGAGCTTGCA TTCTTTGTCT ACTTGAATGA GTCCCTGACA 
ACTGGTGGCT GGGAAGGGGA TAGTCTACTT CTGTTCTTTG CAGGCCTTGG TGAAGGTCAA 
TGCAAAACTG AAACCAATGC TGGATTCAGT GGCTGCCAAC CGAAGGAAGT GGGAAGAGTT 
GCACCAAAAA AGACTACAGG TCTCGGCTGC CTCCCCAGAC CCTGCCAGTC CCATGGTGGC 
CGGGGAAGAC AGACTGTAAA CCACCCAGAG CCGCTGCGCC ACCCTGTGGT CGGGAGGGTC 
CTCCGCATCC TGAACTACTT GCTTTGGTTG AACCGCAACA TCCTATTGGT TCAGCTCGGA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pde11a ( NM_001081033.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001074502.1 Mus musculus phosphodiesterase 11A (Pde11a), mRNA.

Price & Availability↑

CloneID	OMu01562
Clone ID Related Accession (Same CDS sequence)	NM_001081033.2 , NM_001081033.1 , NM_001081033.3
Accession Version	NM_001081033.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2802bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-27
Organism	Mus musculus(house mouse)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL845373.12, AL929133.4 and AL772341.12. On Apr 26, 2018 this sequence version replaced NM_001081033.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC158125.1, SRR1660823.191717.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC AGTGGCTGCC 
AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC TGCCTCCCCA 
GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074502.1
CDS	187..2988
Translation	MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASSLAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQKRLQVSAASPDPASPMVAGEDRL

Target ORF information:

RefSeq Version	NM_001081033.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphodiesterase 11A (Pde11a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001081033.2

ORF Insert Sequence:

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC AGTGGCTGCC 
AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC TGCCTCCCCA 
GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pde11a ( NM_001081033.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001074502.1 Mus musculus phosphodiesterase 11A (Pde11a), mRNA.

Price & Availability↑

CloneID	OMu01562
Clone ID Related Accession (Same CDS sequence)	NM_001081033.2 , NM_001081033.1 , NM_001081033.3
Accession Version	NM_001081033.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2802bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Mus musculus(house mouse)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL845373.12, AL929133.4 and AL772341.12. On Feb 6, 2007 this sequence version replaced XM_001003960.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC158125.1, SRR1660823.191717.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC AGTGGCTGCC 
AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC TGCCTCCCCA 
GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074502.1
CDS	47..2848
Translation	MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASSLAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQKRLQVSAASPDPASPMVAGEDRL

Target ORF information:

RefSeq Version	NM_001081033.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphodiesterase 11A (Pde11a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001081033.1

ORF Insert Sequence:

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC AGTGGCTGCC 
AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC TGCCTCCCCA 
GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pde11a ( NM_001081033.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001074502.1 Mus musculus phosphodiesterase 11A (Pde11a), mRNA.

Price & Availability↑

CloneID	OMu01562
Clone ID Related Accession (Same CDS sequence)	NM_001081033.2 , NM_001081033.1 , NM_001081033.3
Accession Version	NM_001081033.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2802bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-04
Organism	Mus musculus(house mouse)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL845373.12, AL929133.4 and AL772341.12. On Dec 5, 2019 this sequence version replaced NM_001081033.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC158125.1, SRR1660825.191717.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC AGTGGCTGCC 
AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC TGCCTCCCCA 
GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074502.1
CDS	332..3133
Translation	MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASSLAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQKRLQVSAASPDPASPMVAGEDRL

Target ORF information:

RefSeq Version	NM_001081033.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphodiesterase 11A (Pde11a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001081033.3

ORF Insert Sequence:

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC AGTGGCTGCC 
AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC TGCCTCCCCA 
GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pde11a ( XM_006499453.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499516.1 Mus musculus phosphodiesterase 11A (Pde11a), transcript variant X1, mRNA.

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CloneID	OMu30434
Clone ID Related Accession (Same CDS sequence)	XM_006499453.2
Accession Version	XM_006499453.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3036bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006499453.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGAGCA TCGGCAGCAA CATCCGTGGT CCTGAGTTTC TCACAGAAAG CACAGAGCTT 
GCATTCTTTG TCTACTTGAA TGAGTCCCTG ACAACTGGTG GCTGGGAAGG GGATAGTCTA 
CTTCTGTTCT TTGCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC 
AGTGGCTGCC AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC 
TGCCTCCCCA GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AAACCACCCA 
GAGCCGCTGC GCCACCCTGT GGTCGGGAGG GTCCTCCGCA TCCTGAACTA CTTGCTTTGG 
TTGAACCGCA ACATCCTATT GGTTCAGCTC GGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499516.1
CDS	539..3574
Translation	MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASSLAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQSIGSNIRGPEFLTESTELAFFVYLNESLTTGGWEGDSLLLFFAGLGEGQCKTETNAGFSGCQPKEVGRVAPKKTTGLGCLPRPCQSHGGRGRQTVNHPEPLRHPVVGRVLRILNYLLWLNRNILLVQLG

Target ORF information:

RefSeq Version	XM_006499453.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus phosphodiesterase 11A (Pde11a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499453.2

ORF Insert Sequence:

ATGGCAGCCT CCCGCCTGGA CTTCGGGGAG GTGGAAACTT TCCTGGATAG GCACCCAGAG 
TTGTTTGAAG ATTACTTGAT GCGAAAAGGA AAACAGGAAC TGGTGGACAA GTGGCTACAA 
AGGCACACTT CTGGACAGGG GGCTTCAAGC CTGAGGCCTG CCCTGGCTGG CGCTAGCAGC 
TTGGCTCAGA GCAATGCTAA AGGCAGCCCT GGCATAGGTG GTGGTGCTGG ACCCCAGGGC 
TCTGCCCACA GCCATCCCAC GCCCGGTGGT GGGGAAAGTG CTGGGGTTCC CTTGAGTCCC 
AGTTGGGCCA GTGGCAGCCG GGGTGATGGC AGCCTGCAGC GGAGAGCTTC GCAGAAAGAG 
CTGAGGAAGA GCTTTGCCCG CTCCAAAGCC ATCCATGTGA ACAGGACCTA CGATGAACAG 
GTGACCTCCC GGGCCCAGGA GCCCCTGAGC AGTGTCCGGA GGAGAGCCCT GCTCAGAAAG 
GCCAGCTCTC TGCCCCCCAC CACAGCTCAC ATTCTAAGTG CCCTGCTGGA ATCGAGGGTG 
AATCTGCCTC AGTATCCCCC TACGGCCATC GACTACAAAT GCCACCTCAA AAAGCATAAC 
GAGCGCCAGT TTTTCCTGGA ACTGGTCAAG GACATCTCCA ATGACCTTGA CCTCACCAGC 
CTAAGCTACA AGATCCTCAT CTTTGTCTGT CTCATGGTGG ACGCTGACCG TTGCTCTCTC 
TTCTTAGTGG AAGGGGCAGC TGCTGGCAAG AAGACGTTGG TCTCCAAGTT TTTTGATGTG 
CACGCAGGAA CCCCACTGCT CCCCTGCAGT AGCACAGAGA ACTCAAATGA GGTGCAAGTC 
CCCTGGGGCA AAGGTATCAT TGGCTATGTC GGGGAACACG GAGAAACTGT TAACATCCCG 
GATGCCTACC AGGACCGAAG ATTCAATGAT GAAATTGACA AGCTGACTGG ATACAAGACA 
AAATCACTAT TGTGCATGCC CATTCGGAAC AGCGACGGGG AGATTATCGG TGTGGCCCAG 
GCGATAAATA AGGTCCCTGA GGGTGCTCCA TTTACAGAAG ATGACGAAAA AGTTATGCAA 
ATGTATCTTC CGTTCTGTGG AATCGCCATA TCTAATGCTC AGCTCTTCGC TGCCTCAAGG 
AAAGAATACG AAAGAAGCAG GGCCCTGCTG GAGGTGGTCA ATGACCTCTT TGAAGAACAG 
ACTGATCTGG AAAAGATTGT CAAGAAAATA ATGCATCGGG CCCAAACTCT GCTGAAATGT 
GAACGCTGTT CCGTCTTACT TCTAGAAGAC ATTGAGTCCC CAGTGGTGAA GTTTACCAAA 
TCCTTTGAAC TGATGTCCCC AAAGTGCAGC GCTGATGCTG AGAACAGTTT CAAAGAGAGT 
GTGGAGAAAT CGTCTTACTC TGACTGGCTG ATAAACAACA GCATCGCTGA GCTGGTTGCT 
TCGACAGGCC TTCCTGTGAA TGTCAGCGAT GCCTACCAGG ACCCACGCTT TGACGCTGAG 
GCTGACCAGA TATCTGGTTT TCATATAAGA TCTGTTCTCT GTGTCCCCAT TTGGAACAGC 
AACCACCAAA TAATTGGGGT GGCTCAAGTG TTGAACAGAC TCGACGGAAA ACCTTTTGAT 
GATGCAGACC AAAGGCTTTT TGAGGCCTTT GTCATCTTTT GTGGCCTTGG TATTAACAAC 
ACAATTATGT ACGATCAAGT GAAGAAGTCC TGGGCCAAGC AGTCTGTGGC CCTTGATGTG 
CTGTCGTACC ACGCCACGTG TTCCAAGGCT GAAGTCGACA AGTTTAAGGC AGCCAACATC 
CCTCTGGTGT CGGAACTGGC CATCGATGAC ATCCATTTCG ATGACTTTTC CCTTGATGTT 
GATGCCATGA TCACAGCCGC TCTACGGATG TTCATGGAGC TGGGGATGGT ACAGAAATTT 
AAAATCGACT ATGAGACCCT GTGCAGGTGG CTTCTGACGG TAAGGAAAAA CTATCGGATG 
GTTCTCTACC ACAACTGGAG ACATGCCTTC AACGTGTGCC AACTGATGTT TGCCATGCTA 
ACTACTGCTG GGTTCCAAGA GATTCTGACC GAGGTGGAAA TTTTAGCGGT GATTGTGGGA 
TGCCTGTGTC ATGACCTCGA CCACAGGGGA ACCAACAATG CCTTCCAAGC TAAGAGTGAC 
TCTGCACTGG CCCAGCTCTA CGGGACCTCG GCGACCTTGG AGCATCACCA TTTTAACCAT 
GCTGTGATGA TCCTTCAGAG TGAGGGTCAC AACATCTTTG CTAATTTGTC CTCCAAGGAA 
TACAGTGACC TCATGCAGCT CCTGAAGCAG TCAATATTAG CCACAGACCT CACGCTCTAC 
TTTGAGAGAA GAACTGAGTT CTTCGAGCTT GTCAGGAAAG GAGACTACGA TTGGAGCATC 
ACAAGCCACC GAGATGTGTT CCGATCAATG TTAATGACAG CCTGTGACCT TGGAGCCGTG 
ACCAAACCGT GGGAGATCTC CAGACAGGTG GCTGAACTTG TAACCAGCGA GTTCTTTGAA 
CAAGGAGATC GGGAGAGGTC GGAACTCAAG CTCACTCCCT CTGCTATTTT TGACCGGAAC 
CGGAAAGATG AACTGCCTCG GTTGCAGCTG GAGTGGATTG ATAGCATCTG CATGCCTTTG 
TATCAGAGCA TCGGCAGCAA CATCCGTGGT CCTGAGTTTC TCACAGAAAG CACAGAGCTT 
GCATTCTTTG TCTACTTGAA TGAGTCCCTG ACAACTGGTG GCTGGGAAGG GGATAGTCTA 
CTTCTGTTCT TTGCAGGCCT TGGTGAAGGT CAATGCAAAA CTGAAACCAA TGCTGGATTC 
AGTGGCTGCC AACCGAAGGA AGTGGGAAGA GTTGCACCAA AAAAGACTAC AGGTCTCGGC 
TGCCTCCCCA GACCCTGCCA GTCCCATGGT GGCCGGGGAA GACAGACTGT AAACCACCCA 
GAGCCGCTGC GCCACCCTGT GGTCGGGAGG GTCCTCCGCA TCCTGAACTA CTTGCTTTGG 
TTGAACCGCA ACATCCTATT GGTTCAGCTC GGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PDE11A negatively regulates lithium responsivity.
Molecular psychiatry22(12)1714-1724(2017 Dec)
Pathak G,Agostino MJ,Bishara K,Capell WR,Fisher JL,Hegde S,Ibrahim BA,Pilarzyk K,Sabin C,Tuczkewycz T,Wilson S,Kelly MP

Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity.
Cell171(3)522-539.e20(2017 Oct)
Paul A,Crow M,Raudales R,He M,Gillis J,Huang ZJ

Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology41(12)2920-2931(2016 Nov)
Hegde S,Capell WR,Ibrahim BA,Klett J,Patel NS,Sougiannis AT,Kelly MP

PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain.
Neuroscience335151-69(2016 Oct)
Hegde S,Ji H,Oliver D,Patel NS,Poupore N,Shtutman M,Kelly MP

A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron83(2)309-323(2014 Jul)
Thompson CL,Ng L,Menon V,Martinez S,Lee CK,Glattfelder K,Sunkin SM,Henry A,Lau C,Dang C,Garcia-Lopez R,Martinez-Ferre A,Pombero A,Rubenstein JLR,Wakeman WB,Hohmann J,Dee N,Sodt AJ,Young R,Smith K,Nguyen TN,Kidney J,Kuan L,Jeromin A,Kaykas A,Miller J,Page D,Orta G,Bernard A,Riley Z,Smith S,Wohnoutka P,Hawrylycz MJ,Puelles L,Jones AR

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Pde11a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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