Gene Symbol | Adamts4 |
Entrez Gene ID | 240913 |
Full Name | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 |
Synonyms | ADAM-TS4,ADAMTS-2,ADMP-1 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome | |
Summary | This gene encodes a member of 'a disintegrin and metalloproteinase with thrombospondin motifs' (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active zinc-dependent aggrecanase enzyme that degrades cartilage. [provided by RefSeq, Jul 2016]. |