Lax1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lax1
Entrez Gene ID	240754
Full Name	lymphocyte transmembrane adaptor 1
Synonyms	A530029E09,E430019B13Rik
General protein information	Preferred Names lymphocyte transmembrane adaptor 1 Names lymphocyte transmembrane adapter 1 linker for activation of X cells membrane-associated adapter protein LAX
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 E4

mRNA and Protein(s)

mRNA	Protein	Name
NM_001159649.1	NP_001153121.1	lymphocyte transmembrane adapter 1
XM_030253996.1	XP_030109856.1	lymphocyte transmembrane adapter 1 isoform X3
XM_006529557.4	XP_006529620.1	lymphocyte transmembrane adapter 1 isoform X1
XM_030253995.1	XP_030109855.1	lymphocyte transmembrane adapter 1 isoform X2
XM_006529557.3	XP_006529620.1	lymphocyte transmembrane adapter 1 isoform X1
NM_172842.3	NP_766430.3	lymphocyte transmembrane adapter 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LAX1	XP_001156566.1
Mus musculus (house mouse)	Lax1	NP_001153121.1
Homo sapiens (human)	LAX1	NP_060243.2
Bos taurus (cattle)	LAX1	NP_001015674.1
Rattus norvegicus (Norway rat)	Lax1	NP_001017491.1
	LAX1	XP_001101278.1
Canis lupus familiaris (dog)	LAX1	XP_003434375.2

Gene Ontology
Bibliography

Related articles in PubMed

Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX.
Arndt B, Kalinski T, Reinhold D, Thielitz A, Roessner A, Schraven B, Simeoni L
Journal of leukocyte biology93(3)353-62(2013 Mar)

Molecular genetic analysis of two loci (Ity2 and Ity3) involved in the host response to infection with Salmonella typhimurium using congenic mice and expression profiling.
Sancho-Shimizu V, Khan R, Mostowy S, Larivi?re L, Wilkinson R, Riendeau N, Behr M, Malo D
Genetics177(2)1125-39(2007 Oct)

Negative regulation of Fc epsilonRI-mediated signaling and mast cell function by the adaptor protein LAX.
Zhu M, Rhee I, Liu Y, Zhang W
The Journal of biological chemistry281(27)18408-13(2006 Jul)

Negative regulation of lymphocyte activation by the adaptor protein LAX.
Zhu M, Granillo O, Wen R, Yang K, Dai X, Wang D, Zhang W
Journal of immunology (Baltimore, Md. : 1950)174(9)5612-9(2005 May)

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.
Zhu M, Janssen E, Leung K, Zhang W
The Journal of biological chemistry277(48)46151-8(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SIT and LAX are important negative regulators of immune responses that functionally cooperate.
Title: Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX.

LAX negatively regulates mast cell function
Title: Negative regulation of Fc epsilonRI-mediated signaling and mast cell function by the adaptor protein LAX.

Upon T or B cell activation, the LAX protein is up-regulated dramatically. This in vivo study of LAX-deficient mice demonstrates that LAX functions as a negative regulator in lymphocyte signaling.
Title: Negative regulation of lymphocyte activation by the adaptor protein LAX.

The following Lax1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lax1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04144	NM_001159649.1 Latest version!	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu04144	NM_172842.3 Latest version!	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu04144	XM_006529557.4 Latest version!	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu85158	XM_030253995.1 Latest version!	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu85159	XM_030253996.1 Latest version!	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu04144	XM_006529557.3	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lax1 ( NM_001159649.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001153121.1 Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04144
Clone ID Related Accession (Same CDS sequence)	NM_001159649.1 , XM_006529557.4 , XM_006529557.3 , NM_172842.3
Accession Version	NM_001159649.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	lymphocyte transmembrane adapter 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124338.11 and AY090785.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK040834.1, AK088503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153121.1
CDS	399..1622
Translation	MYSTPAPPEVTRRNSEPSTRQGTLGSLQGEKGQIIFPGFVVLLTIILVIIAACILWSWKKQKKRPVPYFQVAPSLTLPPPRHRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEAPQANGSLQMHRVSVHTVEYSVNIYDNGTVPQMCRHLASSTHHVCVRTSRSNPSISSKESNDYVNIPTVEDTCETLTRIESTPENHLGLPSALRLEFAEGGHAGCGNATDHDGFWAPGPKCSDSLSDGDDLSQTSNDYVNMTGLDLENIQENRPRGAFQCCRDYENVPWVDTNESQLPTLEEVASSTVDHREPVWRTLSSVYHMAFQPSAQSEDSAMVHREEQSSEDSSDYETVLVAELEGRDWKQGPGTQHPSDEGTPGDLAGKLCEVVYPAGSLATETSDEDA

Target ORF information:

RefSeq Version	NM_001159649.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159649.1

ORF Insert Sequence:

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lax1 ( NM_172842.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_766430.3 Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu04144
Clone ID Related Accession (Same CDS sequence)	NM_001159649.1 , XM_006529557.4 , XM_006529557.3 , NM_172842.3
Accession Version	NM_172842.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Mus musculus(house mouse)
Product	lymphocyte transmembrane adapter 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC124338.11 and AY090785.1. On Apr 25, 2009 this sequence version replaced NM_172842.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC042765.1, BF536786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849383 [ECO:0000348] ##Evidence-Data-END##

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_766430.3
CDS	301..1524
Translation	MYSTPAPPEVTRRNSEPSTRQGTLGSLQGEKGQIIFPGFVVLLTIILVIIAACILWSWKKQKKRPVPYFQVAPSLTLPPPRHRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEAPQANGSLQMHRVSVHTVEYSVNIYDNGTVPQMCRHLASSTHHVCVRTSRSNPSISSKESNDYVNIPTVEDTCETLTRIESTPENHLGLPSALRLEFAEGGHAGCGNATDHDGFWAPGPKCSDSLSDGDDLSQTSNDYVNMTGLDLENIQENRPRGAFQCCRDYENVPWVDTNESQLPTLEEVASSTVDHREPVWRTLSSVYHMAFQPSAQSEDSAMVHREEQSSEDSSDYETVLVAELEGRDWKQGPGTQHPSDEGTPGDLAGKLCEVVYPAGSLATETSDEDA

Target ORF information:

RefSeq Version	NM_172842.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172842.3

ORF Insert Sequence:

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lax1 ( XM_006529557.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529620.1 Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu04144
Clone ID Related Accession (Same CDS sequence)	NM_001159649.1 , XM_006529557.4 , XM_006529557.3 , NM_172842.3
Accession Version	XM_006529557.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	lymphocyte transmembrane adapter 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006529557.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529620.1
CDS	883..2106
Translation	MYSTPAPPEVTRRNSEPSTRQGTLGSLQGEKGQIIFPGFVVLLTIILVIIAACILWSWKKQKKRPVPYFQVAPSLTLPPPRHRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEAPQANGSLQMHRVSVHTVEYSVNIYDNGTVPQMCRHLASSTHHVCVRTSRSNPSISSKESNDYVNIPTVEDTCETLTRIESTPENHLGLPSALRLEFAEGGHAGCGNATDHDGFWAPGPKCSDSLSDGDDLSQTSNDYVNMTGLDLENIQENRPRGAFQCCRDYENVPWVDTNESQLPTLEEVASSTVDHREPVWRTLSSVYHMAFQPSAQSEDSAMVHREEQSSEDSSDYETVLVAELEGRDWKQGPGTQHPSDEGTPGDLAGKLCEVVYPAGSLATETSDEDA

Target ORF information:

RefSeq Version	XM_006529557.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529557.3

ORF Insert Sequence:

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lax1 ( XM_006529557.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529620.1 Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.

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CloneID	OMu04144
Clone ID Related Accession (Same CDS sequence)	NM_001159649.1 , XM_006529557.4 , XM_006529557.3 , NM_172842.3
Accession Version	XM_006529557.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	lymphocyte transmembrane adapter 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529557.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529620.1
CDS	876..2099
Translation	MYSTPAPPEVTRRNSEPSTRQGTLGSLQGEKGQIIFPGFVVLLTIILVIIAACILWSWKKQKKRPVPYFQVAPSLTLPPPRHRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEAPQANGSLQMHRVSVHTVEYSVNIYDNGTVPQMCRHLASSTHHVCVRTSRSNPSISSKESNDYVNIPTVEDTCETLTRIESTPENHLGLPSALRLEFAEGGHAGCGNATDHDGFWAPGPKCSDSLSDGDDLSQTSNDYVNMTGLDLENIQENRPRGAFQCCRDYENVPWVDTNESQLPTLEEVASSTVDHREPVWRTLSSVYHMAFQPSAQSEDSAMVHREEQSSEDSSDYETVLVAELEGRDWKQGPGTQHPSDEGTPGDLAGKLCEVVYPAGSLATETSDEDA

Target ORF information:

RefSeq Version	XM_006529557.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529557.4

ORF Insert Sequence:

ATGTACAGCA CCCCGGCCCC TCCAGAGGTC ACAAGAAGGA ACTCAGAGCC CAGCACTCGG 
CAGGGGACTC TTGGCAGCCT GCAGGGAGAG AAAGGCCAGA TCATCTTCCC TGGCTTTGTC 
GTGCTCCTGA CCATCATCCT GGTCATCATA GCTGCCTGTA TCCTGTGGAG CTGGAAGAAA 
CAGAAGAAGC GGCCTGTTCC TTACTTCCAA GTAGCTCCAT CGTTGACTCT GCCTCCACCC 
AGACATCGAG CCAAAAATAT TTATGACTTC TTGCCCCGGC AGCAGACAGA GCTGGGGAGA 
CATCAGTTGA GTGGTTTCAG TACCGAGAGC CTCCTCTCCA GAGCATCTGA CAGCCCTGAG 
CCTGAGGCCC CCCAAGCCAA TGGTTCCCTT CAGATGCATA GAGTGTCCGT TCATACTGTG 
GAGTATTCAG TAAACATCTA TGACAATGGC ACAGTGCCCC AGATGTGCAG GCACCTGGCC 
TCCTCAACAC ATCATGTCTG TGTCAGAACT TCCAGAAGTA ACCCCAGCAT TTCTTCCAAG 
GAGTCAAATG ATTATGTCAA TATCCCCACA GTAGAGGACA CCTGTGAGAC TCTAACTCGC 
ATAGAAAGCA CTCCTGAAAA TCACCTTGGT CTTCCAAGTG CCCTGCGGCT GGAGTTTGCT 
GAAGGAGGGC ATGCAGGCTG TGGGAATGCC ACGGACCACG ATGGTTTTTG GGCTCCAGGA 
CCCAAGTGCA GTGATTCACT CAGCGACGGA GACGATTTAT CTCAGACTTC AAATGACTAC 
GTCAATATGA CAGGGTTGGA TCTTGAGAAC ATCCAAGAGA ATCGACCCAG GGGAGCTTTT 
CAGTGCTGCA GAGATTATGA AAATGTCCCA TGGGTAGATA CCAATGAGAG CCAGCTGCCG 
ACTCTGGAAG AAGTGGCATC GTCAACTGTA GACCACAGGG AACCTGTCTG GAGGACCCTC 
TCTTCAGTGT ATCATATGGC ATTTCAGCCG TCGGCACAGA GTGAGGACAG TGCCATGGTC 
CATAGAGAAG AGCAGTCAAG CGAAGACTCC AGTGACTATG AGACTGTGCT GGTTGCTGAG 
TTAGAAGGCA GGGACTGGAA GCAGGGACCT GGTACTCAGC ATCCTTCTGA TGAAGGAACA 
CCAGGCGACC TAGCTGGAAA GCTCTGTGAG GTGGTCTACC CTGCTGGGTC TTTAGCCACC 
GAAACATCTG ATGAAGATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lax1 ( XM_030253995.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030109855.1 Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X2, mRNA.

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CloneID	OMu85158
Clone ID Related Accession (Same CDS sequence)	XM_030253995.1
Accession Version	XM_030253995.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	lymphocyte transmembrane adapter 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTTCTC CAGCATTCCC AAGCCCAAAT CCTATGGCCA CCTGGAGCAT GACACCTGGT 
TTTCCTCCTA GAGAGAAAGG CCAGATCATC TTCCCTGGCT TTGTCGTGCT CCTGACCATC 
ATCCTGGTCA TCATAGCTGC CTGTATCCTG TGGAGCTGGA AGAAACAGAA GAAGCGGCCT 
GTTCCTTACT TCCAAGTAGC TCCATCGTTG ACTCTGCCTC CACCCAGACA TCGAGCCAAA 
AATATTTATG ACTTCTTGCC CCGGCAGCAG ACAGAGCTGG GGAGACATCA GTTGAGTGGT 
TTCAGTACCG AGAGCCTCCT CTCCAGAGCA TCTGACAGCC CTGAGCCTGA GGCCCCCCAA 
GCCAATGGTT CCCTTCAGAT GCATAGAGTG TCCGTTCATA CTGTGGAGTA TTCAGTAAAC 
ATCTATGACA ATGGCACAGT GCCCCAGATG TGCAGGCACC TGGCCTCCTC AACACATCAT 
GTCTGTGTCA GAACTTCCAG AAGTAACCCC AGCATTTCTT CCAAGGAGTC AAATGATTAT 
GTCAATATCC CCACAGTAGA GGACACCTGT GAGACTCTAA CTCGCATAGA AAGCACTCCT 
GAAAATCACC TTGGTCTTCC AAGTGCCCTG CGGCTGGAGT TTGCTGAAGG AGGGCATGCA 
GGCTGTGGGA ATGCCACGGA CCACGATGGT TTTTGGGCTC CAGGACCCAA GTGCAGTGAT 
TCACTCAGCG ACGGAGACGA TTTATCTCAG ACTTCAAATG ACTACGTCAA TATGACAGGG 
TTGGATCTTG AGAACATCCA AGAGAATCGA CCCAGGGGAG CTTTTCAGTG CTGCAGAGAT 
TATGAAAATG TCCCATGGGT AGATACCAAT GAGAGCCAGC TGCCGACTCT GGAAGAAGTG 
GCATCGTCAA CTGTAGACCA CAGGGAACCT GTCTGGAGGA CCCTCTCTTC AGTGTATCAT 
ATGGCATTTC AGCCGTCGGC ACAGAGTGAG GACAGTGCCA TGGTCCATAG AGAAGAGCAG 
TCAAGCGAAG ACTCCAGTGA CTATGAGACT GTGCTGGTTG CTGAGTTAGA AGGCAGGGAC 
TGGAAGCAGG GACCTGGTAC TCAGCATCCT TCTGATGAAG GAACACCAGG CGACCTAGCT 
GGAAAGCTCT GTGAGGTGGT CTACCCTGCT GGGTCTTTAG CCACCGAAAC ATCTGATGAA 
GATGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030109855.1
CDS	5162..6370
Translation	MSSPAFPSPNPMATWSMTPGFPPREKGQIIFPGFVVLLTIILVIIAACILWSWKKQKKRPVPYFQVAPSLTLPPPRHRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEAPQANGSLQMHRVSVHTVEYSVNIYDNGTVPQMCRHLASSTHHVCVRTSRSNPSISSKESNDYVNIPTVEDTCETLTRIESTPENHLGLPSALRLEFAEGGHAGCGNATDHDGFWAPGPKCSDSLSDGDDLSQTSNDYVNMTGLDLENIQENRPRGAFQCCRDYENVPWVDTNESQLPTLEEVASSTVDHREPVWRTLSSVYHMAFQPSAQSEDSAMVHREEQSSEDSSDYETVLVAELEGRDWKQGPGTQHPSDEGTPGDLAGKLCEVVYPAGSLATETSDEDA

Target ORF information:

RefSeq Version	XM_030253995.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030253995.1

ORF Insert Sequence:

ATGTCTTCTC CAGCATTCCC AAGCCCAAAT CCTATGGCCA CCTGGAGCAT GACACCTGGT 
TTTCCTCCTA GAGAGAAAGG CCAGATCATC TTCCCTGGCT TTGTCGTGCT CCTGACCATC 
ATCCTGGTCA TCATAGCTGC CTGTATCCTG TGGAGCTGGA AGAAACAGAA GAAGCGGCCT 
GTTCCTTACT TCCAAGTAGC TCCATCGTTG ACTCTGCCTC CACCCAGACA TCGAGCCAAA 
AATATTTATG ACTTCTTGCC CCGGCAGCAG ACAGAGCTGG GGAGACATCA GTTGAGTGGT 
TTCAGTACCG AGAGCCTCCT CTCCAGAGCA TCTGACAGCC CTGAGCCTGA GGCCCCCCAA 
GCCAATGGTT CCCTTCAGAT GCATAGAGTG TCCGTTCATA CTGTGGAGTA TTCAGTAAAC 
ATCTATGACA ATGGCACAGT GCCCCAGATG TGCAGGCACC TGGCCTCCTC AACACATCAT 
GTCTGTGTCA GAACTTCCAG AAGTAACCCC AGCATTTCTT CCAAGGAGTC AAATGATTAT 
GTCAATATCC CCACAGTAGA GGACACCTGT GAGACTCTAA CTCGCATAGA AAGCACTCCT 
GAAAATCACC TTGGTCTTCC AAGTGCCCTG CGGCTGGAGT TTGCTGAAGG AGGGCATGCA 
GGCTGTGGGA ATGCCACGGA CCACGATGGT TTTTGGGCTC CAGGACCCAA GTGCAGTGAT 
TCACTCAGCG ACGGAGACGA TTTATCTCAG ACTTCAAATG ACTACGTCAA TATGACAGGG 
TTGGATCTTG AGAACATCCA AGAGAATCGA CCCAGGGGAG CTTTTCAGTG CTGCAGAGAT 
TATGAAAATG TCCCATGGGT AGATACCAAT GAGAGCCAGC TGCCGACTCT GGAAGAAGTG 
GCATCGTCAA CTGTAGACCA CAGGGAACCT GTCTGGAGGA CCCTCTCTTC AGTGTATCAT 
ATGGCATTTC AGCCGTCGGC ACAGAGTGAG GACAGTGCCA TGGTCCATAG AGAAGAGCAG 
TCAAGCGAAG ACTCCAGTGA CTATGAGACT GTGCTGGTTG CTGAGTTAGA AGGCAGGGAC 
TGGAAGCAGG GACCTGGTAC TCAGCATCCT TCTGATGAAG GAACACCAGG CGACCTAGCT 
GGAAAGCTCT GTGAGGTGGT CTACCCTGCT GGGTCTTTAG CCACCGAAAC ATCTGATGAA 
GATGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lax1 ( XM_030253996.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030109856.1 Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu85159
Clone ID Related Accession (Same CDS sequence)	XM_030253996.1
Accession Version	XM_030253996.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 831bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	lymphocyte transmembrane adapter 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATAGAG TGTCCGTTCA TACTGTGGAG TATTCAGTAA ACATCTATGA CAATGGCACA 
GTGCCCCAGA TGTGCAGGCA CCTGGCCTCC TCAACACATC ATGTCTGTGT CAGAACTTCC 
AGAAGTAACC CCAGCATTTC TTCCAAGGAG TCAAATGATT ATGTCAATAT CCCCACAGTA 
GAGGACACCT GTGAGACTCT AACTCGCATA GAAAGCACTC CTGAAAATCA CCTTGGTCTT 
CCAAGTGCCC TGCGGCTGGA GTTTGCTGAA GGAGGGCATG CAGGCTGTGG GAATGCCACG 
GACCACGATG GTTTTTGGGC TCCAGGACCC AAGTGCAGTG ATTCACTCAG CGACGGAGAC 
GATTTATCTC AGACTTCAAA TGACTACGTC AATATGACAG GGTTGGATCT TGAGAACATC 
CAAGAGAATC GACCCAGGGG AGCTTTTCAG TGCTGCAGAG ATTATGAAAA TGTCCCATGG 
GTAGATACCA ATGAGAGCCA GCTGCCGACT CTGGAAGAAG TGGCATCGTC AACTGTAGAC 
CACAGGGAAC CTGTCTGGAG GACCCTCTCT TCAGTGTATC ATATGGCATT TCAGCCGTCG 
GCACAGAGTG AGGACAGTGC CATGGTCCAT AGAGAAGAGC AGTCAAGCGA AGACTCCAGT 
GACTATGAGA CTGTGCTGGT TGCTGAGTTA GAAGGCAGGG ACTGGAAGCA GGGACCTGGT 
ACTCAGCATC CTTCTGATGA AGGAACACCA GGCGACCTAG CTGGAAAGCT CTGTGAGGTG 
GTCTACCCTG CTGGGTCTTT AGCCACCGAA ACATCTGATG AAGATGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030109856.1
CDS	449..1279
Translation	MHRVSVHTVEYSVNIYDNGTVPQMCRHLASSTHHVCVRTSRSNPSISSKESNDYVNIPTVEDTCETLTRIESTPENHLGLPSALRLEFAEGGHAGCGNATDHDGFWAPGPKCSDSLSDGDDLSQTSNDYVNMTGLDLENIQENRPRGAFQCCRDYENVPWVDTNESQLPTLEEVASSTVDHREPVWRTLSSVYHMAFQPSAQSEDSAMVHREEQSSEDSSDYETVLVAELEGRDWKQGPGTQHPSDEGTPGDLAGKLCEVVYPAGSLATETSDEDA

Target ORF information:

RefSeq Version	XM_030253996.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lymphocyte transmembrane adaptor 1 (Lax1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030253996.1

ORF Insert Sequence:

ATGCATAGAG TGTCCGTTCA TACTGTGGAG TATTCAGTAA ACATCTATGA CAATGGCACA 
GTGCCCCAGA TGTGCAGGCA CCTGGCCTCC TCAACACATC ATGTCTGTGT CAGAACTTCC 
AGAAGTAACC CCAGCATTTC TTCCAAGGAG TCAAATGATT ATGTCAATAT CCCCACAGTA 
GAGGACACCT GTGAGACTCT AACTCGCATA GAAAGCACTC CTGAAAATCA CCTTGGTCTT 
CCAAGTGCCC TGCGGCTGGA GTTTGCTGAA GGAGGGCATG CAGGCTGTGG GAATGCCACG 
GACCACGATG GTTTTTGGGC TCCAGGACCC AAGTGCAGTG ATTCACTCAG CGACGGAGAC 
GATTTATCTC AGACTTCAAA TGACTACGTC AATATGACAG GGTTGGATCT TGAGAACATC 
CAAGAGAATC GACCCAGGGG AGCTTTTCAG TGCTGCAGAG ATTATGAAAA TGTCCCATGG 
GTAGATACCA ATGAGAGCCA GCTGCCGACT CTGGAAGAAG TGGCATCGTC AACTGTAGAC 
CACAGGGAAC CTGTCTGGAG GACCCTCTCT TCAGTGTATC ATATGGCATT TCAGCCGTCG 
GCACAGAGTG AGGACAGTGC CATGGTCCAT AGAGAAGAGC AGTCAAGCGA AGACTCCAGT 
GACTATGAGA CTGTGCTGGT TGCTGAGTTA GAAGGCAGGG ACTGGAAGCA GGGACCTGGT 
ACTCAGCATC CTTCTGATGA AGGAACACCA GGCGACCTAG CTGGAAAGCT CTGTGAGGTG 
GTCTACCCTG CTGGGTCTTT AGCCACCGAA ACATCTGATG AAGATGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX.
Journal of leukocyte biology93(3)353-62(2013 Mar)
Arndt B,Kalinski T,Reinhold D,Thielitz A,Roessner A,Schraven B,Simeoni L

Molecular genetic analysis of two loci (Ity2 and Ity3) involved in the host response to infection with Salmonella typhimurium using congenic mice and expression profiling.
Genetics177(2)1125-39(2007 Oct)
Sancho-Shimizu V,Khan R,Mostowy S,Larivi?re L,Wilkinson R,Riendeau N,Behr M,Malo D

Negative regulation of Fc epsilonRI-mediated signaling and mast cell function by the adaptor protein LAX.
The Journal of biological chemistry281(27)18408-13(2006 Jul)
Zhu M,Rhee I,Liu Y,Zhang W

Negative regulation of lymphocyte activation by the adaptor protein LAX.
Journal of immunology (Baltimore, Md. : 1950)174(9)5612-9(2005 May)
Zhu M,Granillo O,Wen R,Yang K,Dai X,Wang D,Zhang W

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.
The Journal of biological chemistry277(48)46151-8(2002 Nov)
Zhu M,Janssen E,Leung K,Zhang W

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Lax1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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