Dazap2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dazap2
Entrez Gene ID	23994
Full Name	DAZ associated protein 2
Synonyms	AI314727,Brbp,Gcap28,Prtb,gt6-12,mKIAA0058
General protein information	Preferred Names DAZ associated protein 2 Names DAZ-associated protein 2 deleted in azoospermia-associated protein 2 granule cell antiserum positive 28 proline-rich protein expressed in brain
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 F1\|15 56.36 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006520986.3	XP_006521049.1	DAZ-associated protein 2 isoform X1
NM_011873.2	NP_036003.2	DAZ-associated protein 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	DAZAP2	XP_005636871.1
Homo sapiens (human)	DAZAP2	NP_055579.1
Mus musculus (house mouse)	Dazap2	NP_036003.2
Danio rerio (zebrafish)	dazap2	NP_956087.1
Xenopus tropicalis (tropical clawed frog)	dazap2	NP_989336.1
Bos taurus (cattle)	DAZAP2	NP_001029873.1
Pan troglodytes (chimpanzee)	DAZAP2	XP_003952239.1

Gene Ontology
Bibliography

Related articles in PubMed

TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.
Zepp JA, Wu L, Qian W, Ouyang W, Aronica M, Erzurum S, Li X
Journal of immunology (Baltimore, Md. : 1950)194(6)2826-37(2015 Mar)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

Dazap2 modulates transcription driven by the Wnt effector TCF-4.
Lukas J, Mazna P, Valenta T, Doubravska L, Pospichalova V, Vojtechova M, Fafilek B, Ivanek R, Plachy J, Novak J, Korinek V
Nucleic acids research37(9)3007-20(2009 May)

Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling.
Winkel A, Stricker S, Tylzanowski P, Seiffart V, Mundlos S, Gross G, Hoffmann A
Cellular signalling20(11)2134-44(2008 Nov)

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Nagase T, Ohara O, Koga H
DNA research : an international journal for rapid publication of reports on genes and genomes10(4)167-80(2003 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that TNF receptor associated factor 4 (TRAF4) recruited the E3-ligase SMURF2, to degrade the IL-25R-inhibitory molecule DAZ associated protein 2 (DAZAP2).
Title: TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.

This paper reveals that the mouse DAZAP2 homolog interacts with Sox6 and may be involved in the regulation of a cardiac L-type Ca2+ channel.
Title: Sox6 regulation of cardiac myocyte development.

role as an immediate early, serum-responsive, and adhesion-inducible gene with possible involvement in cell cycle control, adhesion, and proliferation
Title: Proline-rich transcript of the brain (prtb) is a serum-responsive gene in osteoblasts and upregulated during adhesion.

The following Dazap2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dazap2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu51321	XM_006520986.3 Latest version!	Mus musculus DAZ associated protein 2 (Dazap2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu09049	NM_011873.2 Latest version!	Mus musculus DAZ associated protein 2 (Dazap2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dazap2 ( XM_006520986.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521049.1 Mus musculus DAZ associated protein 2 (Dazap2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51321
Clone ID Related Accession (Same CDS sequence)	XM_006520986.3
Accession Version	XM_006520986.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	DAZ-associated protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520986.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGCTG CATTTCCTGG CGCCTCATTG TATCTGCCTA TGGCCCAGTC TGTGGCTGTT 
GGGCCTCTAG GCTCCACAAT CCCCATGGCT TATTATCCAG TTGGTCCCAT CTATCCACCT 
GGCTCAGCAG TGTTGGTGGA AGGAGGGTAT GATGCAGGTG CCAGATTTGG AGCTGGTGCC 
ACTGCTGGCA ACATTCCTCC TCCACCTCCT GGATGCCCTC CCAACGCTGC TCAGCTCGCA 
GTCATGCAGG GAGCCAACGT CCTTGTAACT CAGCGCAAGG GAAACTTCTT CATGGGTGGC 
TCAGATGGTG GCTACACCAT TTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521049.1
CDS	441..767
Translation	MSAAFPGASLYLPMAQSVAVGPLGSTIPMAYYPVGPIYPPGSAVLVEGGYDAGARFGAGATAGNIPPPPPGCPPNAAQLAVMQGANVLVTQRKGNFFMGGSDGGYTIW

Target ORF information:

RefSeq Version	XM_006520986.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus DAZ associated protein 2 (Dazap2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520986.3

ORF Insert Sequence:

ATGTCAGCTG CATTTCCTGG CGCCTCATTG TATCTGCCTA TGGCCCAGTC TGTGGCTGTT 
GGGCCTCTAG GCTCCACAAT CCCCATGGCT TATTATCCAG TTGGTCCCAT CTATCCACCT 
GGCTCAGCAG TGTTGGTGGA AGGAGGGTAT GATGCAGGTG CCAGATTTGG AGCTGGTGCC 
ACTGCTGGCA ACATTCCTCC TCCACCTCCT GGATGCCCTC CCAACGCTGC TCAGCTCGCA 
GTCATGCAGG GAGCCAACGT CCTTGTAACT CAGCGCAAGG GAAACTTCTT CATGGGTGGC 
TCAGATGGTG GCTACACCAT TTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dazap2 ( NM_011873.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036003.2 Mus musculus DAZ associated protein 2 (Dazap2), mRNA.

Price & Availability↑

CloneID	OMu09049
Clone ID Related Accession (Same CDS sequence)	NM_011873.2
Accession Version	NM_011873.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Mus musculus(house mouse)
Product	DAZ-associated protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC014808.1. On Jun 19, 2003 this sequence version replaced NM_011873.1. ##Evidence-Data-START## Transcript exon combination :: BC014808.1, BC083347.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAACAGCA AAGGTCAATA TCCAACACAG CCTACCTACC CTGTGCAACC TCCTGGGAAT 
CCAGTATATC CTCAGACCTT ACATCTTCCT CAGGCTCCAC CCTATACTGA TGCTCCACCT 
GCATATTCAG AGCTCTATCG TCCAAGCTTT GTTCATCCAG GGGCTGCCAC AGTCCCCACC 
ATGTCAGCTG CATTTCCTGG CGCCTCATTG TATCTGCCTA TGGCCCAGTC TGTGGCTGTT 
GGGCCTCTAG GCTCCACAAT CCCCATGGCT TATTATCCAG TTGGTCCCAT CTATCCACCT 
GGCTCAGCAG TGTTGGTGGA AGGAGGGTAT GATGCAGGTG CCAGATTTGG AGCTGGTGCC 
ACTGCTGGCA ACATTCCTCC TCCACCTCCT GGATGCCCTC CCAACGCTGC TCAGCTCGCA 
GTCATGCAGG GAGCCAACGT CCTTGTAACT CAGCGCAAGG GAAACTTCTT CATGGGTGGC 
TCAGATGGTG GCTACACCAT TTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036003.2
CDS	51..557
Translation	MNSKGQYPTQPTYPVQPPGNPVYPQTLHLPQAPPYTDAPPAYSELYRPSFVHPGAATVPTMSAAFPGASLYLPMAQSVAVGPLGSTIPMAYYPVGPIYPPGSAVLVEGGYDAGARFGAGATAGNIPPPPPGCPPNAAQLAVMQGANVLVTQRKGNFFMGGSDGGYTIW

Target ORF information:

RefSeq Version	NM_011873.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus DAZ associated protein 2 (Dazap2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011873.2

ORF Insert Sequence:

ATGAACAGCA AAGGTCAATA TCCAACACAG CCTACCTACC CTGTGCAACC TCCTGGGAAT 
CCAGTATATC CTCAGACCTT ACATCTTCCT CAGGCTCCAC CCTATACTGA TGCTCCACCT 
GCATATTCAG AGCTCTATCG TCCAAGCTTT GTTCATCCAG GGGCTGCCAC AGTCCCCACC 
ATGTCAGCTG CATTTCCTGG CGCCTCATTG TATCTGCCTA TGGCCCAGTC TGTGGCTGTT 
GGGCCTCTAG GCTCCACAAT CCCCATGGCT TATTATCCAG TTGGTCCCAT CTATCCACCT 
GGCTCAGCAG TGTTGGTGGA AGGAGGGTAT GATGCAGGTG CCAGATTTGG AGCTGGTGCC 
ACTGCTGGCA ACATTCCTCC TCCACCTCCT GGATGCCCTC CCAACGCTGC TCAGCTCGCA 
GTCATGCAGG GAGCCAACGT CCTTGTAACT CAGCGCAAGG GAAACTTCTT CATGGGTGGC 
TCAGATGGTG GCTACACCAT TTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.
Journal of immunology (Baltimore, Md. : 1950)194(6)2826-37(2015 Mar)
Zepp JA,Wu L,Qian W,Ouyang W,Aronica M,Erzurum S,Li X

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

Dazap2 modulates transcription driven by the Wnt effector TCF-4.
Nucleic acids research37(9)3007-20(2009 May)
Lukas J,Mazna P,Valenta T,Doubravska L,Pospichalova V,Vojtechova M,Fafilek B,Ivanek R,Plachy J,Novak J,Korinek V

Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling.
Cellular signalling20(11)2134-44(2008 Nov)
Winkel A,Stricker S,Tylzanowski P,Seiffart V,Mundlos S,Gross G,Hoffmann A

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
DNA research : an international journal for rapid publication of reports on genes and genomes10(4)167-80(2003 Aug)
Okazaki N,Kikuno R,Ohara R,Inamoto S,Koseki H,Hiraoka S,Saga Y,Nagase T,Ohara O,Koga H

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Dazap2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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