Prkra cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prkra
Entrez Gene ID	23992
Full Name	protein kinase, interferon inducible double stranded RNA dependent activator
Synonyms	AV120107,PRK,Pact,RAX,lear
General protein information	Preferred Names protein kinase, interferon inducible double stranded RNA dependent activator Names interferon-inducible double-stranded RNA-dependent protein kinase activator A PKR-associated protein X PKR-associating protein X protein activator of the interferon-induced protein kinase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_011871.2	NP_036001.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A
XM_030250934.1	XP_030106794.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1
XM_011239518.2	XP_011237820.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2
XM_011239517.2	XP_011237819.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1
XM_017318023.1	XP_017173512.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X3
XM_030250935.1	XP_030106795.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2
XM_017318023.2	XP_017173512.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X3
NM_011871.3	NP_036001.1	interferon-inducible double-stranded RNA-dependent protein kinase activator A

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009781	XP_318876.4
Xenopus tropicalis (tropical clawed frog)	prkra	XP_004917795.1
Rattus norvegicus (Norway rat)	Prkra	NP_001019951.1
Drosophila melanogaster (fruit fly)	loqs	NP_609646.1
	PRKRA	XP_001098685.1
Canis lupus familiaris (dog)	PRKRA	XP_545545.2
Danio rerio (zebrafish)	prkra	NP_001082830.1
Homo sapiens (human)	PRKRA	NP_003681.1
Pan troglodytes (chimpanzee)	PRKRA	XP_515940.2
Bos taurus (cattle)	PRKRA	NP_001039335.1
Mus musculus (house mouse)	Prkra	NP_036001.1

Gene Ontology
Bibliography

Related articles in PubMed

PACT is required for MDA5-mediated immunoresponses triggered by Cardiovirus infection via interaction with LGP2.
Miyamoto M, Komuro A
Biochemical and biophysical research communications494(1-2)227-233(2017 12)

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.
Dickerman BK, White CL, Kessler PM, Sadler AJ, Williams BR, Sen GC
The FEBS journal282(24)4766-81(2015 Dec)

PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load.
Poon DC, Ho YS, You R, Tse HL, Chiu K, Chang RC
Journal of neuroinflammation12212(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PACT interacts with LGP2 and this interaction is enhanced by encephalomyocarditis virus (EMCV) infection. In vitro interaction analyses using purified recombinant proteins confirmed that the single-stranded Theiler's murine encephalitis virus genome enhanced the interaction between LGP2 and PACT.
Title: PACT is required for MDA5-mediated immunoresponses triggered by Cardiovirus infection via interaction with LGP2.

Data (including data from studies in transgenic/knockout mice) suggest that PACT/RAX (protein activator of protein kinase R) functions as negative regulator of PKR/Eif2ak2 (protein kinase R) in development of postnatal anterior pituitary tissue.
Title: The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.

Deficiency of PKR diminished peripheral inflammatory responses following E. coli
Title: PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load.

These findings demonstrated a novel function of PACT/RAX in the regulation of neuronal migration.
Title: PACT/RAX regulates the migration of cerebellar granule neurons in the developing cerebellum.

The protein kinase PKR is critical for LPS-induced iNOS production but is dispensable for inflammasome activation in macrophages.
Title: The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages.

The following Prkra gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prkra cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu69160	XM_011239517.2 Latest version!	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu69161	XM_011239518.2 Latest version!	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu19641	NM_011871.3 Latest version!	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu69160	XM_030250934.1 Latest version!	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu69161	XM_030250935.1 Latest version!	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu80244	XM_017318023.2 Latest version!	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu80244	XM_017318023.1	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu19641	NM_011871.2	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prkra ( XM_011239517.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237819.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69160
Clone ID Related Accession (Same CDS sequence)	XM_030250934.1 , XM_011239517.2
Accession Version	XM_011239517.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011239517.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGTC AATTGTGGAT GGGTGGCCAA GCCTCAATTG GACCGACCAG AACCCAAGAT 
TTTGTCTTAA ACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237819.1
CDS	100..1197
Translation	MAERGGAERLGREGVWPALPRRGPASPSFSSCPLAGGRQAAIRGASKRQRGHAPLGNWPTWRGRTQIHTSLDCCGQPSLLAMSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIGQLWMGGQASIGPTRTQDFVLNS

Target ORF information:

RefSeq Version	XM_011239517.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239517.2

ORF Insert Sequence:

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGTC AATTGTGGAT GGGTGGCCAA GCCTCAATTG GACCGACCAG AACCCAAGAT 
TTTGTCTTAA ACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prkra ( XM_011239518.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237820.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu69161
Clone ID Related Accession (Same CDS sequence)	XM_011239518.2 , XM_030250935.1
Accession Version	XM_011239518.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011239518.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGCT TCAGGGACCA AGGCCAGGTC TCCAGGCTTG TGCAGCAAGT GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237820.1
CDS	100..1176
Translation	MAERGGAERLGREGVWPALPRRGPASPSFSSCPLAGGRQAAIRGASKRQRGHAPLGNWPTWRGRTQIHTSLDCCGQPSLLAMSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIGFRDQGQVSRLVQQVP

Target ORF information:

RefSeq Version	XM_011239518.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239518.2

ORF Insert Sequence:

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGCT TCAGGGACCA AGGCCAGGTC TCCAGGCTTG TGCAGCAAGT GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prkra ( XM_017318023.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173512.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu80244
Clone ID Related Accession (Same CDS sequence)	XM_017318023.1 , XM_017318023.2
Accession Version	XM_017318023.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGATC CATCCAAACA GCCGAAGAAC CAGCTGAATC CAATTGGCTC ATTACAGGAA 
TTAGCAATTC ACCATGGCTG GCGACTTCCT GAATATACCC TTTCCCAGGA AGGAGGACCG 
GCTCATAAGA GGGAATACAC CACGATCTGC AGGCTTGAAT CATTCATGGA AACTGGAAAG 
GGGGCATCAA AAAAACAAGC CAAGAGAAAT GCTGCTGAGA AATTTCTCGC CAAGTTTAGT 
AATATTTCTC CAGAGAACCA CATTTCTCTA ACGAACGTGG TTGGACATTC CCTAGGATGC 
ACTTGGCACT CCTTGAGGAA TTCCCCTGGT GAGAAGATCA ACCTCCTGAA AAGGAGCCTC 
CTCAGTCTCC CGAACACAGA CTACATCCAG CTGCTTAGTG AGATTGCCAG CGAGCAAGGC 
TTTAACATAA CGTATTTGGA TATAGAGGAG CTGAGTGCCA ACGGACAGTA TCAGTGTCTC 
GCAGAGCTGT CCACCAGTCC TATCACCGTG TGTCACGGCT CAGGCATCTC CTGTGGCAAT 
GCACAGAGTG ACGCTGCTCA CAATGCTCTG CAGTATTTAA AGATAATAGC AGAAAGAAAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173512.1
CDS	188..790
Translation	MPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK

Target ORF information:

RefSeq Version	XM_017318023.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318023.1

ORF Insert Sequence:

ATGCCTGATC CATCCAAACA GCCGAAGAAC CAGCTGAATC CAATTGGCTC ATTACAGGAA 
TTAGCAATTC ACCATGGCTG GCGACTTCCT GAATATACCC TTTCCCAGGA AGGAGGACCG 
GCTCATAAGA GGGAATACAC CACGATCTGC AGGCTTGAAT CATTCATGGA AACTGGAAAG 
GGGGCATCAA AAAAACAAGC CAAGAGAAAT GCTGCTGAGA AATTTCTCGC CAAGTTTAGT 
AATATTTCTC CAGAGAACCA CATTTCTCTA ACGAACGTGG TTGGACATTC CCTAGGATGC 
ACTTGGCACT CCTTGAGGAA TTCCCCTGGT GAGAAGATCA ACCTCCTGAA AAGGAGCCTC 
CTCAGTCTCC CGAACACAGA CTACATCCAG CTGCTTAGTG AGATTGCCAG CGAGCAAGGC 
TTTAACATAA CGTATTTGGA TATAGAGGAG CTGAGTGCCA ACGGACAGTA TCAGTGTCTC 
GCAGAGCTGT CCACCAGTCC TATCACCGTG TGTCACGGCT CAGGCATCTC CTGTGGCAAT 
GCACAGAGTG ACGCTGCTCA CAATGCTCTG CAGTATTTAA AGATAATAGC AGAAAGAAAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prkra ( NM_011871.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036001.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), mRNA.

Price & Availability↑

CloneID	OMu19641
Clone ID Related Accession (Same CDS sequence)	NM_011871.2 , NM_011871.3
Accession Version	NM_011871.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL928867.9. On Nov 17, 2006 this sequence version replaced NM_011871.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF083032.1, BC011311.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137, SAMN01164139 [ECO:0000348] ##Evidence-Data-END##

ATGTCCCATA GCAGGCATCG TGCCGAGGCC CCGCCGCTGC AGCGCGAGGA CAGCGGGACC 
TTCAGTTTGG GCAAGATGAT AACAGCTAAG CCTGGGAAAA CACCGATTCA GGTATTGCAC 
GAGTACGGCA TGAAGACCAA GAACATTCCA GTTTATGAAT GTGAAAGATC CGATGTGCAA 
GTACACGTGC CCACTTTCAC CTTCAGAGTA ACCGTTGGTG ACATAACTTG CACAGGTGAA 
GGTACAAGTA AGAAGCTGGC GAAGCACAGA GCTGCGGAGG CCGCCATAAA CATTTTGAAA 
GCCAATGCAA GTATTTGCTT TGCAGTTCCT GACCCCTTAA TGCCTGATCC ATCCAAACAG 
CCGAAGAACC AGCTGAATCC AATTGGCTCA TTACAGGAAT TAGCAATTCA CCATGGCTGG 
CGACTTCCTG AATATACCCT TTCCCAGGAA GGAGGACCGG CTCATAAGAG GGAATACACC 
ACGATCTGCA GGCTTGAATC ATTCATGGAA ACTGGAAAGG GGGCATCAAA AAAACAAGCC 
AAGAGAAATG CTGCTGAGAA ATTTCTCGCC AAGTTTAGTA ATATTTCTCC AGAGAACCAC 
ATTTCTCTAA CGAACGTGGT TGGACATTCC CTAGGATGCA CTTGGCACTC CTTGAGGAAT 
TCCCCTGGTG AGAAGATCAA CCTCCTGAAA AGGAGCCTCC TCAGTCTCCC GAACACAGAC 
TACATCCAGC TGCTTAGTGA GATTGCCAGC GAGCAAGGCT TTAACATAAC GTATTTGGAT 
ATAGAGGAGC TGAGTGCCAA CGGACAGTAT CAGTGTCTCG CAGAGCTGTC CACCAGTCCT 
ATCACCGTGT GTCACGGCTC AGGCATCTCC TGTGGCAATG CACAGAGTGA CGCTGCTCAC 
AATGCTCTGC AGTATTTAAA GATAATAGCA GAAAGAAAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036001.1
CDS	139..1080
Translation	MSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK

Target ORF information:

RefSeq Version	NM_011871.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011871.2

ORF Insert Sequence:

ATGTCCCATA GCAGGCATCG TGCCGAGGCC CCGCCGCTGC AGCGCGAGGA CAGCGGGACC 
TTCAGTTTGG GCAAGATGAT AACAGCTAAG CCTGGGAAAA CACCGATTCA GGTATTGCAC 
GAGTACGGCA TGAAGACCAA GAACATTCCA GTTTATGAAT GTGAAAGATC CGATGTGCAA 
GTACACGTGC CCACTTTCAC CTTCAGAGTA ACCGTTGGTG ACATAACTTG CACAGGTGAA 
GGTACAAGTA AGAAGCTGGC GAAGCACAGA GCTGCGGAGG CCGCCATAAA CATTTTGAAA 
GCCAATGCAA GTATTTGCTT TGCAGTTCCT GACCCCTTAA TGCCTGATCC ATCCAAACAG 
CCGAAGAACC AGCTGAATCC AATTGGCTCA TTACAGGAAT TAGCAATTCA CCATGGCTGG 
CGACTTCCTG AATATACCCT TTCCCAGGAA GGAGGACCGG CTCATAAGAG GGAATACACC 
ACGATCTGCA GGCTTGAATC ATTCATGGAA ACTGGAAAGG GGGCATCAAA AAAACAAGCC 
AAGAGAAATG CTGCTGAGAA ATTTCTCGCC AAGTTTAGTA ATATTTCTCC AGAGAACCAC 
ATTTCTCTAA CGAACGTGGT TGGACATTCC CTAGGATGCA CTTGGCACTC CTTGAGGAAT 
TCCCCTGGTG AGAAGATCAA CCTCCTGAAA AGGAGCCTCC TCAGTCTCCC GAACACAGAC 
TACATCCAGC TGCTTAGTGA GATTGCCAGC GAGCAAGGCT TTAACATAAC GTATTTGGAT 
ATAGAGGAGC TGAGTGCCAA CGGACAGTAT CAGTGTCTCG CAGAGCTGTC CACCAGTCCT 
ATCACCGTGT GTCACGGCTC AGGCATCTCC TGTGGCAATG CACAGAGTGA CGCTGCTCAC 
AATGCTCTGC AGTATTTAAA GATAATAGCA GAAAGAAAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prkra ( NM_011871.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036001.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), mRNA.

Price & Availability↑

CloneID	OMu19641
Clone ID Related Accession (Same CDS sequence)	NM_011871.2 , NM_011871.3
Accession Version	NM_011871.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928867.9. On Apr 24, 2018 this sequence version replaced NM_011871.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK155112.1, BC011311.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCCATA GCAGGCATCG TGCCGAGGCC CCGCCGCTGC AGCGCGAGGA CAGCGGGACC 
TTCAGTTTGG GCAAGATGAT AACAGCTAAG CCTGGGAAAA CACCGATTCA GGTATTGCAC 
GAGTACGGCA TGAAGACCAA GAACATTCCA GTTTATGAAT GTGAAAGATC CGATGTGCAA 
GTACACGTGC CCACTTTCAC CTTCAGAGTA ACCGTTGGTG ACATAACTTG CACAGGTGAA 
GGTACAAGTA AGAAGCTGGC GAAGCACAGA GCTGCGGAGG CCGCCATAAA CATTTTGAAA 
GCCAATGCAA GTATTTGCTT TGCAGTTCCT GACCCCTTAA TGCCTGATCC ATCCAAACAG 
CCGAAGAACC AGCTGAATCC AATTGGCTCA TTACAGGAAT TAGCAATTCA CCATGGCTGG 
CGACTTCCTG AATATACCCT TTCCCAGGAA GGAGGACCGG CTCATAAGAG GGAATACACC 
ACGATCTGCA GGCTTGAATC ATTCATGGAA ACTGGAAAGG GGGCATCAAA AAAACAAGCC 
AAGAGAAATG CTGCTGAGAA ATTTCTCGCC AAGTTTAGTA ATATTTCTCC AGAGAACCAC 
ATTTCTCTAA CGAACGTGGT TGGACATTCC CTAGGATGCA CTTGGCACTC CTTGAGGAAT 
TCCCCTGGTG AGAAGATCAA CCTCCTGAAA AGGAGCCTCC TCAGTCTCCC GAACACAGAC 
TACATCCAGC TGCTTAGTGA GATTGCCAGC GAGCAAGGCT TTAACATAAC GTATTTGGAT 
ATAGAGGAGC TGAGTGCCAA CGGACAGTAT CAGTGTCTCG CAGAGCTGTC CACCAGTCCT 
ATCACCGTGT GTCACGGCTC AGGCATCTCC TGTGGCAATG CACAGAGTGA CGCTGCTCAC 
AATGCTCTGC AGTATTTAAA GATAATAGCA GAAAGAAAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036001.1
CDS	172..1113
Translation	MSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK

Target ORF information:

RefSeq Version	NM_011871.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011871.3

ORF Insert Sequence:

ATGTCCCATA GCAGGCATCG TGCCGAGGCC CCGCCGCTGC AGCGCGAGGA CAGCGGGACC 
TTCAGTTTGG GCAAGATGAT AACAGCTAAG CCTGGGAAAA CACCGATTCA GGTATTGCAC 
GAGTACGGCA TGAAGACCAA GAACATTCCA GTTTATGAAT GTGAAAGATC CGATGTGCAA 
GTACACGTGC CCACTTTCAC CTTCAGAGTA ACCGTTGGTG ACATAACTTG CACAGGTGAA 
GGTACAAGTA AGAAGCTGGC GAAGCACAGA GCTGCGGAGG CCGCCATAAA CATTTTGAAA 
GCCAATGCAA GTATTTGCTT TGCAGTTCCT GACCCCTTAA TGCCTGATCC ATCCAAACAG 
CCGAAGAACC AGCTGAATCC AATTGGCTCA TTACAGGAAT TAGCAATTCA CCATGGCTGG 
CGACTTCCTG AATATACCCT TTCCCAGGAA GGAGGACCGG CTCATAAGAG GGAATACACC 
ACGATCTGCA GGCTTGAATC ATTCATGGAA ACTGGAAAGG GGGCATCAAA AAAACAAGCC 
AAGAGAAATG CTGCTGAGAA ATTTCTCGCC AAGTTTAGTA ATATTTCTCC AGAGAACCAC 
ATTTCTCTAA CGAACGTGGT TGGACATTCC CTAGGATGCA CTTGGCACTC CTTGAGGAAT 
TCCCCTGGTG AGAAGATCAA CCTCCTGAAA AGGAGCCTCC TCAGTCTCCC GAACACAGAC 
TACATCCAGC TGCTTAGTGA GATTGCCAGC GAGCAAGGCT TTAACATAAC GTATTTGGAT 
ATAGAGGAGC TGAGTGCCAA CGGACAGTAT CAGTGTCTCG CAGAGCTGTC CACCAGTCCT 
ATCACCGTGT GTCACGGCTC AGGCATCTCC TGTGGCAATG CACAGAGTGA CGCTGCTCAC 
AATGCTCTGC AGTATTTAAA GATAATAGCA GAAAGAAAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prkra ( XM_030250934.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106794.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu69160
Clone ID Related Accession (Same CDS sequence)	XM_030250934.1 , XM_011239517.2
Accession Version	XM_030250934.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGTC AATTGTGGAT GGGTGGCCAA GCCTCAATTG GACCGACCAG AACCCAAGAT 
TTTGTCTTAA ACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106794.1
CDS	106..1203
Translation	MAERGGAERLGREGVWPALPRRGPASPSFSSCPLAGGRQAAIRGASKRQRGHAPLGNWPTWRGRTQIHTSLDCCGQPSLLAMSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIGQLWMGGQASIGPTRTQDFVLNS

Target ORF information:

RefSeq Version	XM_030250934.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250934.1

ORF Insert Sequence:

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGTC AATTGTGGAT GGGTGGCCAA GCCTCAATTG GACCGACCAG AACCCAAGAT 
TTTGTCTTAA ACTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prkra ( XM_030250935.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106795.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu69161
Clone ID Related Accession (Same CDS sequence)	XM_011239518.2 , XM_030250935.1
Accession Version	XM_030250935.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGCT TCAGGGACCA AGGCCAGGTC TCCAGGCTTG TGCAGCAAGT GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106795.1
CDS	106..1182
Translation	MAERGGAERLGREGVWPALPRRGPASPSFSSCPLAGGRQAAIRGASKRQRGHAPLGNWPTWRGRTQIHTSLDCCGQPSLLAMSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIGFRDQGQVSRLVQQVP

Target ORF information:

RefSeq Version	XM_030250935.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250935.1

ORF Insert Sequence:

ATGGCAGAGA GGGGCGGGGC AGAGAGGCTG GGCAGAGAGG GGGTGTGGCC GGCTCTTCCG 
CGCCGAGGCC CCGCCTCTCC TTCCTTCTCC TCCTGTCCCT TAGCTGGAGG GAGGCAGGCA 
GCGATTCGAG GGGCGTCCAA GCGGCAGCGC GGGCACGCTC CTCTCGGGAA CTGGCCGACG 
TGGAGAGGGA GGACCCAGAT CCACACTTCT CTTGATTGCT GTGGCCAGCC GTCCCTTCTC 
GCCATGTCCC ATAGCAGGCA TCGTGCCGAG GCCCCGCCGC TGCAGCGCGA GGACAGCGGG 
ACCTTCAGTT TGGGCAAGAT GATAACAGCT AAGCCTGGGA AAACACCGAT TCAGGTATTG 
CACGAGTACG GCATGAAGAC CAAGAACATT CCAGTTTATG AATGTGAAAG ATCCGATGTG 
CAAGTACACG TGCCCACTTT CACCTTCAGA GTAACCGTTG GTGACATAAC TTGCACAGGT 
GAAGGTACAA GTAAGAAGCT GGCGAAGCAC AGAGCTGCGG AGGCCGCCAT AAACATTTTG 
AAAGCCAATG CAAGTATTTG CTTTGCAGTT CCTGACCCCT TAATGCCTGA TCCATCCAAA 
CAGCCGAAGA ACCAGCTGAA TCCAATTGGC TCATTACAGG AATTAGCAAT TCACCATGGC 
TGGCGACTTC CTGAATATAC CCTTTCCCAG GAAGGAGGAC CGGCTCATAA GAGGGAATAC 
ACCACGATCT GCAGGCTTGA ATCATTCATG GAAACTGGAA AGGGGGCATC AAAAAAACAA 
GCCAAGAGAA ATGCTGCTGA GAAATTTCTC GCCAAGTTTA GTAATATTTC TCCAGAGAAC 
CACATTTCTC TAACGAACGT GGTTGGACAT TCCCTAGGAT GCACTTGGCA CTCCTTGAGG 
AATTCCCCTG GTGAGAAGAT CAACCTCCTG AAAAGGAGCC TCCTCAGTCT CCCGAACACA 
GACTACATCC AGCTGCTTAG TGAGATTGCC AGCGAGCAAG GCTTTAACAT AACGTATTTG 
GATATAGGCT TCAGGGACCA AGGCCAGGTC TCCAGGCTTG TGCAGCAAGT GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prkra ( XM_017318023.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017173512.1 Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu80244
Clone ID Related Accession (Same CDS sequence)	XM_017318023.1 , XM_017318023.2
Accession Version	XM_017318023.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_017318023.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGATC CATCCAAACA GCCGAAGAAC CAGCTGAATC CAATTGGCTC ATTACAGGAA 
TTAGCAATTC ACCATGGCTG GCGACTTCCT GAATATACCC TTTCCCAGGA AGGAGGACCG 
GCTCATAAGA GGGAATACAC CACGATCTGC AGGCTTGAAT CATTCATGGA AACTGGAAAG 
GGGGCATCAA AAAAACAAGC CAAGAGAAAT GCTGCTGAGA AATTTCTCGC CAAGTTTAGT 
AATATTTCTC CAGAGAACCA CATTTCTCTA ACGAACGTGG TTGGACATTC CCTAGGATGC 
ACTTGGCACT CCTTGAGGAA TTCCCCTGGT GAGAAGATCA ACCTCCTGAA AAGGAGCCTC 
CTCAGTCTCC CGAACACAGA CTACATCCAG CTGCTTAGTG AGATTGCCAG CGAGCAAGGC 
TTTAACATAA CGTATTTGGA TATAGAGGAG CTGAGTGCCA ACGGACAGTA TCAGTGTCTC 
GCAGAGCTGT CCACCAGTCC TATCACCGTG TGTCACGGCT CAGGCATCTC CTGTGGCAAT 
GCACAGAGTG ACGCTGCTCA CAATGCTCTG CAGTATTTAA AGATAATAGC AGAAAGAAAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017173512.1
CDS	534..1136
Translation	MPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK

Target ORF information:

RefSeq Version	XM_017318023.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus protein kinase, interferon inducible double stranded RNA dependent activator (Prkra), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017318023.2

ORF Insert Sequence:

ATGCCTGATC CATCCAAACA GCCGAAGAAC CAGCTGAATC CAATTGGCTC ATTACAGGAA 
TTAGCAATTC ACCATGGCTG GCGACTTCCT GAATATACCC TTTCCCAGGA AGGAGGACCG 
GCTCATAAGA GGGAATACAC CACGATCTGC AGGCTTGAAT CATTCATGGA AACTGGAAAG 
GGGGCATCAA AAAAACAAGC CAAGAGAAAT GCTGCTGAGA AATTTCTCGC CAAGTTTAGT 
AATATTTCTC CAGAGAACCA CATTTCTCTA ACGAACGTGG TTGGACATTC CCTAGGATGC 
ACTTGGCACT CCTTGAGGAA TTCCCCTGGT GAGAAGATCA ACCTCCTGAA AAGGAGCCTC 
CTCAGTCTCC CGAACACAGA CTACATCCAG CTGCTTAGTG AGATTGCCAG CGAGCAAGGC 
TTTAACATAA CGTATTTGGA TATAGAGGAG CTGAGTGCCA ACGGACAGTA TCAGTGTCTC 
GCAGAGCTGT CCACCAGTCC TATCACCGTG TGTCACGGCT CAGGCATCTC CTGTGGCAAT 
GCACAGAGTG ACGCTGCTCA CAATGCTCTG CAGTATTTAA AGATAATAGC AGAAAGAAAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PACT is required for MDA5-mediated immunoresponses triggered by Cardiovirus infection via interaction with LGP2.
Biochemical and biophysical research communications494(1-2)227-233(2017 12)
Miyamoto M,Komuro A

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.
The FEBS journal282(24)4766-81(2015 Dec)
Dickerman BK,White CL,Kessler PM,Sadler AJ,Williams BR,Sen GC

PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load.
Journal of neuroinflammation12212(2015 Nov)
Poon DC,Ho YS,You R,Tse HL,Chiu K,Chang RC

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Prkra cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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